Is anodal transcranial direct current stimulation a potential ergogenic resource for muscle strength and effort perception? A critical review

Nas últimas décadas, vários estudos estão investigando a dose-resposta ideal em termos de frequência, intensidade e volume de treinamento para alcançar o aumento da força muscular, tanto em atletas quanto em não atletas. A dose-resposta é fundamental para a prescrição do treinamento, uma vez que sua manipulação equivocada pode acarretar alto risco de desenvolvimento de lesões por esforços repetitivos, bem como pelo não desenvolvimento da força esperada. Em indivíduos com nível avançado de treinamento de força, é extremamente importante aumentar sua intensidade e volume de treinamento. Nesse sentido, com os avanços encontrados na área de treinamento de força e a necessidade de novas estratégias para otimizar ganhos de força, um novo método vem ganhando força na literatura, a estimulação transcraniana por corrente contínua (ETCC). Portanto, o objetivo deste estudo é analisar criticamente os efeitos do ETCC como potencial recurso ergogênico para a realização de força muscular e percepção de esforço, bem como se seu uso é ético ou não. Para tanto, foram pesquisadas as bases de dados Pubmed/Medline, ISI Web of Knowledge e Scielo, apenas em inglês, e com as palavras-chave: força muscular, resistência muscular, estimulação transcraniana por corrente contínua, ETCC. Nós comparamos o efeito do ETCC anódico (ETCC-a) com uma condição sham/controle nos resultados de ETCC para força muscular e percepção de esforço força muscular e percepção de esforço. Nenhum estudo menciona efeitos colaterais negativos da intervenção. Os dados mostram diferenças entre os estudos que investigam os estudos de avaliação da força muscular e resistência muscular, em termos do uso bem sucedido de ETCC. Estudos que investigaram a eficiência do ETCC na melhora da força muscular demonstraram efeitos positivos do ETCC-a em 66,7% dos parâmetros testados. Amaioria dos dados mostra consistentemente a influência do ETCC-a na força muscular, mas não no desempenho de resistênciaEn las últimas décadas, diversos estudios están investigando la dosis-respuesta ideal en cuanto a la frecuencia, intensidad y volumen de entrenamiento para alcanzar el aumento de fuerza muscular, sea en atletas y no atletas. La dosis-respuesta es fundamental para la prescripción de entrenamiento, pues su manipulación equivocada puede llevar a un alto de riesgo de desarrollo de lesiones por esfuerzo repetitivo, así como para el no desarrollo de la fuerza esperada. En sujetos con nivel avanzado de entrenamiento de fuerza es extremadamente importante aumentar su intensidad y volumen de entrenamiento. En este sentido, con los avances encontrados en el área de entrenamiento de fuerza y la necesidad de nuevas estrategias para optimizar las ganancias de fuerza, un nuevo método está ganando fuerza en la literatura, la estimulación transcraneal por corriente continua (ETCC). Por lo tanto, el objetivo del presente estudio es analizar de forma crítica los efectos de la ETCC como potencial recurso ergogénico al desempeño de fuerza muscular y percepción de esfuerzo, así como si su uso es ético o no. Por lo tanto, se realizó una búsqueda en las bases de datos Pubmed/Medline, ISI Web of Knowledge y Scielo, solamente en inglés y con las palabras clave: fuerza muscular, resistencia muscular, estimulación transcraneal de corriente continua, ETCC. Comparamos el efecto de la ETCC anódica (ETCC-a) a una condición sham/control sobre los resultados de la fuerza muscular y percepción de esfuerzo. Ningún estudio menciona efectos secundarios negativos de la intervención. Los datos muestran diferencias entre los estudios que investigan la fuerza muscular y los estudios de evaluación de resistencia muscular, en lo que se refiere al uso exitoso de la ETCC. Los estudios que investigan la eficiencia de la ETCC en la mejora de la fuerza muscular demuestran efectos positivos de la ETCC-a en el 66,7% de los parámetros probados. La mayoría de los datos muestran consistentemente influencia de la ETCC-a en la fuerza muscular, pero no en el rendimiento de resistencia.In the last decades, several studies are investigating the optimal dose-response in terms of frequency, intensity and volume of training to achieve increased muscle strength in both athletes and non-athletes. Dose-response is critical to the prescription of training, since its mismanagement may pose a high risk of developing repetitive strain injuries as well as failure to develop the expected strength. In individuals with advanced level of strength training, it is extremely important to increase their intensity and training volume. In this sense, with the advances in the area of strength training and the need for new strategies to optimize force gains, a new method is gaining strength in the literature, the transcranial direct current stimulation (tDCS). Therefore, the purpose of this study is to critically analyze the effects of tDCS as a potential ergogenic resource for achieving muscle strength and perceived exertion, as well as whether its use is ethical or not. To do so, we searched the databases Pubmed/Medline, ISI Web of Knowledge and Scielo, in English only, and with the keywords: muscle strength, muscular endurance, transcranial direct current stimulation, tDCS. We compared the effect of anodic tDCS (a-tDCS) with a sham/control condition on muscle strength and perceived exertion results. No study mentions the negative side effects of the intervention. The data show differences between studies investigating studies of muscle strength and muscle endurance in terms of the successful use of tDCS. Studies that investigated tDCS efficiency in improving muscle strength demonstrated positive effects of a-tDCS on 66.7% of the parameters tested. Most data consistently show the influence of a-tDCS on muscle strength, but not on resistance performance.info:eu-repo/semantics/publishedVersio

Isotopic and spin selectivity of H_2 adsorbed in bundles of carbon nanotubes

Due to its large surface area and strongly attractive potential, a bundle of carbon nanotubes is an ideal substrate material for gas storage. In addition, adsorption in nanotubes can be exploited in order to separate the components of a mixture. In this paper, we investigate the preferential adsorption of D_2 versus H_2(isotope selectivity) and of ortho versus para(spin selectivity) molecules confined in the one-dimensional grooves and interstitial channels of carbon nanotube bundles. We perform selectivity calculations in the low coverage regime, neglecting interactions between adsorbate molecules. We find substantial spin selectivity for a range of temperatures up to 100 K, and even greater isotope selectivity for an extended range of temperatures,up to 300 K. This isotope selectivity is consistent with recent experimental data, which exhibit a large difference between the isosteric heats of D_2 and H_2 adsorbed in these bundles.Comment: Paper submitted to Phys.Rev. B; 17 pages, 2 tables, 6 figure

Compton Scattering on the Deuteron in Baryon Chiral Perturbation Theory

Compton scattering on the deuteron is studied in the framework of baryon chiral perturbation theory to third order in small momenta, for photon energies of order the pion mass. The scattering amplitude is a sum of one- and two-nucleon mechanisms with no undetermined parameters. Our results are in good agreement with existing experimental data, and a prediction is made for higher-energy data being analyzed at SAL.Comment: 39 pages LaTeX, 19 figures (uses epsf

Measurement of D*+/- meson production in jets from pp collisions at sqrt(s) = 7 TeV with the ATLAS detector

This paper reports a measurement of D*+/- meson production in jets from proton-proton collisions at a center-of-mass energy of sqrt(s) = 7 TeV at the CERN Large Hadron Collider. The measurement is based on a data sample recorded with the ATLAS detector with an integrated luminosity of 0.30 pb^-1 for jets with transverse momentum between 25 and 70 GeV in the pseudorapidity range |eta| < 2.5. D*+/- mesons found in jets are fully reconstructed in the decay chain: D*+ -> D0pi+, D0 -> K-pi+, and its charge conjugate. The production rate is found to be N(D*+/-)/N(jet) = 0.025 +/- 0.001(stat.) +/- 0.004(syst.) for D*+/- mesons that carry a fraction z of the jet momentum in the range 0.3 < z < 1. Monte Carlo predictions fail to describe the data at small values of z, and this is most marked at low jet transverse momentum.Comment: 10 pages plus author list (22 pages total), 5 figures, 1 table, matches published version in Physical Review

Search for supersymmetry in final states with jets, missing transverse momentum and one isolated lepton in sqrt{s} = 7 TeV pp collisions using 1 fb-1 of ATLAS data

We present an update of a search for supersymmetry in final states containing jets, missing transverse momentum, and one isolated electron or muon, using 1.04 fb^-1 of proton-proton collision data at sqrt{s} = 7 TeV recorded by the ATLAS experiment at the LHC in the first half of 2011. The analysis is carried out in four distinct signal regions with either three or four jets and variations on the (missing) transverse momentum cuts, resulting in optimized limits for various supersymmetry models. No excess above the standard model background expectation is observed. Limits are set on the visible cross-section of new physics within the kinematic requirements of the search. The results are interpreted as limits on the parameters of the minimal supergravity framework, limits on cross-sections of simplified models with specific squark and gluino decay modes, and limits on parameters of a model with bilinear R-parity violation.Comment: 18 pages plus author list (30 pages total), 9 figures, 4 tables, final version to appear in Physical Review

Reducing heterotic M-theory to five dimensional supergravity on a manifold with boundary

This paper constructs the reduction of heterotic $M$-theory in eleven dimensions to a supergravity model on a manifold with boundary in five dimensions using a Calabi-Yau three-fold. New results are presented for the boundary terms in the action and for the boundary conditions on the bulk fields. Some general features of dualisation on a manifold with boundary are used to explain the origin of some topological terms in the action. The effect of gaugino condensation on the fermion boundary conditions leads to a `twist' in the chirality of the gravitino which can provide an uplifting mechanism in the vacuum energy to cancel the cosmological constant after moduli stabilisation.Comment: 16 pages, RevTe

The International Pulsar Timing Array: First data release

International audienceThe highly stable spin of neutron stars can be exploited for a variety of (astro)physical investigations. In particular, arrays of pulsars with rotational periods of the order of milliseconds can be used to detect correlated signals such as those caused by gravitational waves. Three such 'pulsar timing arrays' (PTAs) have been set up around the world over the past decades and collectively form the 'International' PTA (IPTA). In this paper, we describe the first joint analysis of the data from the three regional PTAs, i.e. of the first IPTA data set. We describe the available PTA data, the approach presently followed for its combination and suggest improvements for future PTA research. Particular attention is paid to subtle details (such as underestimation of measurement uncertainty and long-period noise) that have often been ignored but which become important in this unprecedentedly large and inhomogeneous data set. We identify and describe in detail several factors that complicate IPTA research and provide recommendations for future pulsar timing efforts. The first IPTA data release presented here (and available on-line) is used to demonstrate the IPTA's potential of improving upon gravitational-wave limit

Measurement of tau polarization in W->taunu decays with the ATLAS detector in pp collisions at sqrt(s) = 7 TeV

In this paper, a measurement of tau polarization in W->taunu decays is presented. It is measured from the energies of the decay products in hadronic tau decays with a single final state charged particle. The data, corresponding to an integrated luminosity of 24 pb^-1, were collected by the ATLAS experiment at the Large Hadron Collider in 2010. The measured value of the tau polarization is Ptau = -1.06 +/- 0.04 (stat) + 0.05 (syst) - 0.07 (syst), in agreement with the Standard Model prediction, and is consistent with a physically allowed 95% CL interval [-1,-0.91]. Measurements of tau polarization have not previously been made at hadron colliders.Comment: 10 pages plus author list (25 pages total), 4 figures, 4 tables, revised author list, matches published EPJC versio

Bio-based synthesis of oxidation resistant copper nanowires using an aqueous plant extract

Copper nanowires have recently emerged as promising nanomaterials for transparent conducting electrodes applications, however, their production commonly involves the use of harmful reagents. In this study, we describe for the first time a simple and cost-effective bio-based synthesis of copper nanowires using an aqueous plant extract (Eucalyptus globulus) as the reducing/stabilizing agent and oleic acid and oleylamine as surfactants. Well-dispersed crystalline copper nanowires (λmáx = 584–613 nm) were obtained with average diameters in the nanometric range (44 and 145 nm) and lengths in the micrometric range (from 5 to dozens of micrometres) using extract concentrations between 10 and 50 mg mL−1. Moreover, the aspect ratio of these nanowires can be adjusted (from around 14–20 to 160–400) by changing the experimental conditions, namely the use of oleic acid. Phenolic compounds were found to have a key role in this bioreduction process allowing to obtain practically only nanowires (without other morphologies). Nevertheless, the use of oleic acid/oleylamine is essential to manipulate their size and aspect ratio. Most importantly, these bio-based copper nanowires were found to be resistant under storage in ethanol and when submitted to air exposure, both for 2 weeks, certainly due to the adsorption of antioxidant biomolecules (phenolic) at their surface, thus avoiding the use of other polymeric protective layers. The conductivity of the CuNWs was found to be 0.009 S cm−1. As a result, this study opens a new standpoint in this field, “closing the door” to the use of hazardous reagents and synthetic polymeric protective layers, on the production of stable copper nanowires with potential application as conductive materials.publishe