A Tamed Nobility? An Evaluation of the Relationship between the English Monarchy and the Late Medieval Peerage

The fifteenth century in England was an extremely tumultuous period. The beginning of the century saw the continuation and eventual end of the Hundred Years War while the latter half saw a period of noble-led civil war known as the Wars of the Roses. The Wars of the Roses lasted for approximately thirty years and spanned the reigns of four kings: Henry VI, Edward IV, Richard III, and Henry VII. The English peerage was intimately involved throughout the entire conflict. Nobles such as Richard, Duke of York and Richard, Earl of Salisbury were responsible for beginning the Wars of the Roses, and other members of the nobility supported the Duke of York and the deposition of Henry VI in favor of Edward IV in 1461. Nine years later, Richard, Earl of Warwick and George, Duke of Clarence were responsible for the brief deposition of Edward IV. In 1483, the Duke of Buckingham aided Richard III in usurping his young nephew. Finally, in 1485, John, Earl of Oxford, Jasper, Earl of Pembroke, and Thomas, Lord Stanley were integral in placing Henry VII on the throne. Some scholars have argued that Henry VII recognized that the main cause of the previous thirty years of civil war was the unrestrained and independent nobility which is why he sought to tame his nobility. This study will look at the Calendar of the Patent Rolls, Calendar of the Fine Rolls, Calendar of the Charter Rolls, and Calendar of the Close Rolls from the reigns of the four kings intimately involved with the Wars of the Roses and its immediate aftermath. These sources will be used to examine the patronage given to the nobility by each king as well as any punitive measures taken against the nobility for misbehavior. This evidence will show that Henry VII did, in fact, tame his nobility. He did so by restricting his patronage to the nobility in comparison to his predecessors. He also placed troublesome nobles under repressive bonds to ensure their loyalty

Magnetospheric Multiscale Mission (MMS) Phase 2B Navigation Performance

The Magnetospheric Multiscale (MMS) formation flying mission, which consists of four spacecraft flying in a tetrahedral formation, has challenging navigation requirements associated with determining and maintaining the relative separations required to meet the science requirements. The baseline navigation concept for MMS is for each spacecraft to independently estimate its position, velocity and clock states using GPS pseudorange data provided by the Goddard Space Flight Center-developed Navigator receiver and maneuver acceleration measurements provided by the spacecraft's attitude control subsystem. State estimation is performed onboard in real-time using the Goddard Enhanced Onboard Navigation System flight software, which is embedded in the Navigator receiver. The current concept of operations for formation maintenance consists of a sequence of two maintenance maneuvers that is performed every 2 weeks. Phase 2b of the MMS mission, in which the spacecraft are in 1.2 x 25 Earth radii orbits with nominal separations at apogee ranging from 30 km to 400 km, has the most challenging navigation requirements because, during this phase, GPS signal acquisition is restricted to less than one day of the 2.8-day orbit. This paper summarizes the results from high-fidelity simulations to determine if the MMS navigation requirements can be met between and immediately following the maintenance maneuver sequence in Phase 2b

Are Advanced Practice Registered Nurses In Mississippi Participating In Practices That Advocate The Nursing Profession

Previous research studies have focused on patient outcomes related to healthcare interventions, but there is little research available regarding nurses’ involvement in activities that would advance the profession. Advanced Practice Registered Nurses’ (APRN) contributions to the healthcare system lead to direct improvement of patient outcomes through research, mentoring new professionals, and participating in professional organizations. The theoretical motivation behind the study is Ray’s Theory of Bureaucratic Caring that proposed healthcare personnel consider incorporation of the business aspects of healthcare to propel nursing into the future. Ray dared nurses to become leaders in the field, understand the corporate aspects of health care, evolve bedside nursing through research activity, and build future nurse leaders with political and mentorship works. The study considers characteristics Ray demanded nurses take to control the future of the profession and advance the nurse’s role in healthcare. The study will assess current level of involvement of APRNs in three activities that directly advance the profession. Survey questions will address demographic information and the degree of participation in the three specific activities. The study will use a quantitative approach through randomized surveys distributed through face-to-face encounters, Survey Monkey, social media, and email. Inclusion criteria is limited to practicing APRNs within any specialty with a master’s level education or higher

Differences in the Use and Perceptions of Evidence-Based Practice between Occupational Therapy Students and Practitioners

This study explored differences in perceptions of evidence-based practice (EBP) between occupational therapy (OT) students and practitioners. Researchers aimed to understand student and practitioner perceptions of barriers, knowledge, attitudes, and confidence in EBP. Occupational therapy students (n=61) and practitioners (n=21) completed an online researcher-created survey and the Evidence-Based Practice Confidence (EPIC) Scale survey. Results indicated practitioners were more confident in utilizing EBP than students, particularly when identifying a gap in knowledge related to a patient (p = \u3c.001) deciding on a course of action for a client (p = \u3c.001), and assessing the efficacy of EBP on client outcomes (p = \u3c.001). This finding was inconsistent with previous research, which may be due to more practitioners receiving formal education on EBP. It is critical for OT education to support student learning and application of clinical reasoning throughout the EBP process in order to increase confidence. This study was limited by the use of a homogenous population from a single university

Summer 1970

The U.S. Nitrogen Industry by George C. Sweeney, Jr. (page 3) Learn the Oil Alphabet by Melvin E. Long (7) Weed Control with Repeated Applications of Tordon Herbicides by John W. Gibson (9) Plants Speed Formation of Soil by Brij L. Sawney (12) St. Augustine Decline (SAD) A Virus Disease of St. Augustine Grass by Norman L. McCoy, Robert W. Toler, and Jose Amador (15) The Problem of Responsibility for Recreation by Ronald F. Paige (19) Editorial (20) Massachusetts Fine Turf Conference (23) Dickinson Memorial Fund (23

Fabular: regression formulas as probabilistic programming

Regression formulas are a domain-specific language adopted by several R packages for describing an important and useful class of statistical models: hierarchical linear regressions. Formulas are succinct, expressive, and clearly popular, so are they a useful addition to probabilistic programming languages? And what do they mean? We propose a core calculus of hierarchical linear regression, in which regression coefficients are themselves defined by nested regressions (unlike in R). We explain how our calculus captures the essence of the formula DSL found in R. We describe the design and implementation of Fabular, a version of the Tabular schema-driven probabilistic programming language, enriched with formulas based on our regression calculus. To the best of our knowledge, this is the first formal description of the core ideas of R's formula notation, the first development of a calculus of regression formulas, and the first demonstration of the benefits of composing regression formulas and latent variables in a probabilistic programming language.Adam Ścibior received travel support from the DARPA PPAML programme. Marcin Szymczak was supported by Microsoft Research through its PhD Scholarship Programme.This is the author accepted manuscript. The final version is available from the Association of Computer Machinery via http://dx.doi.org/10.1145/2837614.283765

Characterization of Aptamer-Protein Complexes by X-ray Crystallography and Alternative Approaches

Aptamers are oligonucleotide ligands, either RNA or ssDNA, selected for high-affinity binding to molecular targets, such as small organic molecules, proteins or whole microorganisms. While reports of new aptamers are numerous, characterization of their specific interaction is often restricted to the affinity of binding (KD). Over the years, crystal structures of aptamer-protein complexes have only scarcely become available. Here we describe some relevant technical issues about the process of crystallizing aptamer-protein complexes and highlight some biochemical details on the molecular basis of selected aptamer-protein interactions. In addition, alternative experimental and computational approaches are discussed to study aptamer-protein interactions.

Measurements of fiducial and differential cross sections for Higgs boson production in the diphoton decay channel at s√=8 TeV with ATLAS

Measurements of fiducial and differential cross sections are presented for Higgs boson production in proton-proton collisions at a centre-of-mass energy of s√=8 TeV. The analysis is performed in the H → γγ decay channel using 20.3 fb−1 of data recorded by the ATLAS experiment at the CERN Large Hadron Collider. The signal is extracted using a fit to the diphoton invariant mass spectrum assuming that the width of the resonance is much smaller than the experimental resolution. The signal yields are corrected for the effects of detector inefficiency and resolution. The pp → H → γγ fiducial cross section is measured to be 43.2 ±9.4(stat.) − 2.9 + 3.2 (syst.) ±1.2(lumi)fb for a Higgs boson of mass 125.4GeV decaying to two isolated photons that have transverse momentum greater than 35% and 25% of the diphoton invariant mass and each with absolute pseudorapidity less than 2.37. Four additional fiducial cross sections and two cross-section limits are presented in phase space regions that test the theoretical modelling of different Higgs boson production mechanisms, or are sensitive to physics beyond the Standard Model. Differential cross sections are also presented, as a function of variables related to the diphoton kinematics and the jet activity produced in the Higgs boson events. The observed spectra are statistically limited but broadly in line with the theoretical expectations

Search for squarks and gluinos in events with isolated leptons, jets and missing transverse momentum at s√=8 TeV with the ATLAS detector

The results of a search for supersymmetry in final states containing at least one isolated lepton (electron or muon), jets and large missing transverse momentum with the ATLAS detector at the Large Hadron Collider are reported. The search is based on proton-proton collision data at a centre-of-mass energy s√=8 TeV collected in 2012, corresponding to an integrated luminosity of 20 fb−1. No significant excess above the Standard Model expectation is observed. Limits are set on supersymmetric particle masses for various supersymmetric models. Depending on the model, the search excludes gluino masses up to 1.32 TeV and squark masses up to 840 GeV. Limits are also set on the parameters of a minimal universal extra dimension model, excluding a compactification radius of 1/R c = 950 GeV for a cut-off scale times radius (ΛR c) of approximately 30