The Italian “No Mommy” women. Motivations for childlessness in the North-East of Italy.

Nowadays about 20% of the female population of industrialized countries conclude their fertility cycle without experiencing motherhood, in the face of a deliberate choice or of certain conditions that have occurred in the courses of life. The procreative project is characterized as one of the many aspects of personal fulfillment on which every woman can decide whether to invest or not, choosing the times and the ways. The present study aims to provide a picture of the No Mommy phenomenon in the North East of Italy, through 50 interviews with women without children: efforts were made to understand what are the motivations underlying childlessness and what are the related factors. Analyses have allowed to identify five different profiles characterizing the childlessness, besides showing the importance of the personal factors (childhood experience, affective relationships, aspirations and expectations) in comparison to the structural factors (economic and working condition, presence of services for childhood)

Le risposte dei servizi ai bisogni delle famiglie adottive: l’accompagnamento nel post-adozione.

Il capitolo presenta una ricerca sulle adozioni internazionali in Italia, principale paese di accoglienza nel contesto europeo, secondo solo agli Stati Uniti a livello mondiale. Attraverso l’analisi delle cartelle sociali di 359 famiglie, sono stati raccolti i dati circa l’evoluzione dell’adozione di 424 bambini. I risultati mostrano come il triennio di postadozione si configuri come un periodo fondamentale per il recupero delle capacità dei minori, in cui le coppie percepiscono le Equipe Adozioni come un importante punto di appoggio, insieme all’importanza data alle reti familiari e sociali, che permettono al bambino di inserirsi positivamente nel nuovo tessuto sociale

Questioni di genere. Quale genere di questioni?

Le questioni di genere all\u2019interno del servizio sociale acquisiscono particolare rilevanza per due principali motivi: la declinazione tipicamente femminile della professione e il costante ma mutevole contatto con un\u2019utenza differenziata in termini di et\ue0, genere, provenienza, cultura. Nel tempo la professione ha spesso sentito il peso delle proprie origini fondate sul lavoro di cura, cercando legittimazione dal punto di vista accademico, istituzionale e sociale. La carenza di riscontri in tal senso che per anni ha accompagnato gli assistenti sociali nel lavoro quotidiano, ha lasciato un alone di incertezza legato alla percezione di mancato riconoscimento come figure professionali. A partire da questa cornice, ci si chiede allora che cosa significhi essere un assistente sociale, essere una donna e dover costruire relazioni di aiuto sempre pi\uf9 complesse in termini di richieste, bisogni e risorse disponibili nei confronti di nuove realt\ue0, come quella dei cittadini migranti che spesso hanno visioni completamente differenti in merito al genere e alla costruzione dei ruoli del maschile e del femminile

The use of discretion in decision-making by social workers at child protection services in Italy

Child protection social workers in Italy operate within a context apparently lacking reference laws on procedures to be implemented in selecting the most appropriate intervention measures for a child\u2019s welfare. The result is a situation leaving significant operational discretion up to each professional who, although able to choose the best possible intervention based on each specific case and on local resources, also risks creating profound inequalities. The objective of this research was to identify the criteria according to which decisions are taken by child protection services social workers in Italy. Three focus groups were formed of 22 social workers operating in protection services in three cities of the Veneto region, in north-eastern Italy. The results highlight certain significant convergences on the social worker\u2019s decision-making criteria, together with the lack of both shared practices, also within individual services, and the use of standardised methods. Moreover, there is a strong shift of decision-making toward the individual rather than the institution and based on experiential-intuitive methods, rather than scientific-analytical ones

Seismic imaging of Late Miocene (Messinian) evaporites from Western Mediterranean back-arc basins

An analysis of multichannel seismic reflection data was conducted focusing on the comparison between the Messinian Salinity Crisis (MSC) and Plio-Quaternary (PQ) evolution of the eastern Sardo-Proven\ue7al and northern Algero- Balearic basins and related margins in the West Mediterranean Sea. Both basins were completely opened during the MSC and their well-defined seismic stratigraphy is very similar in the deep parts. The primary difference between these two basins is due to their different pre-MSC extensional history, including the opening age and the stretching factors. These factors influenced the occurrence of post-MSC salt tectonics on these margins

Validation of an open source, remote web‐based eye‐tracking method (WebGazer) for research in early childhood

Measuring eye movements remotely via the participant's webcam promises to be an attractive methodological addition to in-person eye-tracking in the lab. However, there is a lack of systematic research comparing remote web-based eye-tracking with in-lab eye-tracking in young children. We report a multi-lab study that compared these two measures in an anticipatory looking task with toddlers using WebGazer.js and jsPsych. Results of our remotely tested sample of 18-27-month-old toddlers (N = 125) revealed that web-based eye-tracking successfully captured goal-based action predictions, although the proportion of the goal-directed anticipatory looking was lower compared to the in-lab sample (N = 70). As expected, attrition rate was substantially higher in the web-based (42%) than the in-lab sample (10%). Excluding trials based on visual inspection of the match of time-locked gaze coordinates and the participant's webcam video overlayed on the stimuli was an important preprocessing step to reduce noise in the data. We discuss the use of this remote web-based method in comparison with other current methodological innovations. Our study demonstrates that remote web-based eye-tracking can be a useful tool for testing toddlers, facilitating recruitment of larger and more diverse samples; a caveat to consider is the larger drop-out rate

Refinement of the diagnostic approach for the identification of children and adolescents affected by familial hypercholesterolemia: Evidence from the LIPIGEN study

Background and aims: We aimed to describe the limitations of familiar hypercholesterolemia (FH) diagnosis in childhood based on the presence of the typical features of FH, such as physical sings of cholesterol accumulation and personal or family history of premature cardiovascular disease or hypercholesterolemia, comparing their prevalence in the adult and paediatric FH population, and to illustrate how additional information can lead to a more effective diagnosis of FH at a younger age.Methods: From the Italian LIPIGEN cohort, we selected 1188 (>= 18 years) and 708 (<18 years) genetically-confirmed heterozygous FH, with no missing personal FH features. The prevalence of personal and familial FH features was compared between the two groups. For a sub-group of the paediatric cohort (N = 374), data about premature coronary heart disease (CHD) in second-degree family members were also included in the evaluation.Results: The lower prevalence of typical FH features in children/adolescents vs adults was confirmed: the prevalence of tendon xanthoma was 2.1% vs 13.1%, and arcus cornealis was present in 1.6% vs 11.2% of the cohorts, respectively. No children presented clinical history of premature CHD or cerebral/peripheral vascular disease compared to 8.8% and 5.6% of adults, respectively. The prevalence of premature CHD in first-degree relatives was significantly higher in adults compared to children/adolescents (38.9% vs 19.7%). In the sub-cohort analysis, a premature CHD event in parents was reported in 63 out of 374 subjects (16.8%), but the percentage increased to 54.0% extending the evaluation also to second-degree relatives.Conclusions: In children, the typical FH features are clearly less informative than in adults. A more thorough data collection, adding information about second-degree relatives, could improve the diagnosis of FH at younger age

Lipoprotein(a) Genotype Influences the Clinical Diagnosis of Familial Hypercholesterolemia

: Background Evidence suggests that LPA risk genotypes are a possible contributor to the clinical diagnosis of familial hypercholesterolemia (FH). This study aimed at determining the prevalence of LPA risk variants in adult individuals with FH enrolled in the Italian LIPIGEN (Lipid Transport Disorders Italian Genetic Network) study, with (FH/M+) or without (FH/M-) a causative genetic variant. Methods and Results An lp(a) [lipoprotein(a)] genetic score was calculated by summing the number risk-increasing alleles inherited at rs3798220 and rs10455872 variants. Overall, in the 4.6% of 1695 patients with clinically diagnosed FH, the phenotype was not explained by a monogenic or polygenic cause but by genotype associated with high lp(a) levels. Among 765 subjects with FH/M- and 930 subjects with FH/M+, 133 (17.4%) and 95 (10.2%) were characterized by 1 copy of either rs10455872 or rs3798220 or 2 copies of either rs10455872 or rs3798220 (lp(a) score ≥1). Subjects with FH/M- also had lower mean levels of pretreatment low-density lipoprotein cholesterol than individuals with FH/M+ (t test for difference in means between FH/M- and FH/M+ groups <0.0001); however, subjects with FH/M- and lp(a) score ≥1 had higher mean (SD) pretreatment low-density lipoprotein cholesterol levels (223.47 [50.40] mg/dL) compared with subjects with FH/M- and lp(a) score=0 (219.38 [54.54] mg/dL for), although not statistically significant. The adjustment of low-density lipoprotein cholesterol levels based on lp(a) concentration reduced from 68% to 42% the proportion of subjects with low-density lipoprotein cholesterol level ≥190 mg/dL (or from 68% to 50%, considering a more conservative formula). Conclusions Our study supports the importance of measuring lp(a) to perform the diagnosis of FH appropriately and to exclude that the observed phenotype is driven by elevated levels of lp(a) before performing the genetic test for FH

Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories: a pooled analysis of 2181 population-based studies with 65 million participants

Summary Background Comparable global data on health and nutrition of school-aged children and adolescents are scarce. We aimed to estimate age trajectories and time trends in mean height and mean body-mass index (BMI), which measures weight gain beyond what is expected from height gain, for school-aged children and adolescents. Methods For this pooled analysis, we used a database of cardiometabolic risk factors collated by the Non-Communicable Disease Risk Factor Collaboration. We applied a Bayesian hierarchical model to estimate trends from 1985 to 2019 in mean height and mean BMI in 1-year age groups for ages 5–19 years. The model allowed for non-linear changes over time in mean height and mean BMI and for non-linear changes with age of children and adolescents, including periods of rapid growth during adolescence. Findings We pooled data from 2181 population-based studies, with measurements of height and weight in 65 million participants in 200 countries and territories. In 2019, we estimated a difference of 20 cm or higher in mean height of 19-year-old adolescents between countries with the tallest populations (the Netherlands, Montenegro, Estonia, and Bosnia and Herzegovina for boys; and the Netherlands, Montenegro, Denmark, and Iceland for girls) and those with the shortest populations (Timor-Leste, Laos, Solomon Islands, and Papua New Guinea for boys; and Guatemala, Bangladesh, Nepal, and Timor-Leste for girls). In the same year, the difference between the highest mean BMI (in Pacific island countries, Kuwait, Bahrain, The Bahamas, Chile, the USA, and New Zealand for both boys and girls and in South Africa for girls) and lowest mean BMI (in India, Bangladesh, Timor-Leste, Ethiopia, and Chad for boys and girls; and in Japan and Romania for girls) was approximately 9–10 kg/m2. In some countries, children aged 5 years started with healthier height or BMI than the global median and, in some cases, as healthy as the best performing countries, but they became progressively less healthy compared with their comparators as they grew older by not growing as tall (eg, boys in Austria and Barbados, and girls in Belgium and Puerto Rico) or gaining too much weight for their height (eg, girls and boys in Kuwait, Bahrain, Fiji, Jamaica, and Mexico; and girls in South Africa and New Zealand). In other countries, growing children overtook the height of their comparators (eg, Latvia, Czech Republic, Morocco, and Iran) or curbed their weight gain (eg, Italy, France, and Croatia) in late childhood and adolescence. When changes in both height and BMI were considered, girls in South Korea, Vietnam, Saudi Arabia, Turkey, and some central Asian countries (eg, Armenia and Azerbaijan), and boys in central and western Europe (eg, Portugal, Denmark, Poland, and Montenegro) had the healthiest changes in anthropometric status over the past 3·5 decades because, compared with children and adolescents in other countries, they had a much larger gain in height than they did in BMI. The unhealthiest changes—gaining too little height, too much weight for their height compared with children in other countries, or both—occurred in many countries in sub-Saharan Africa, New Zealand, and the USA for boys and girls; in Malaysia and some Pacific island nations for boys; and in Mexico for girls. Interpretation The height and BMI trajectories over age and time of school-aged children and adolescents are highly variable across countries, which indicates heterogeneous nutritional quality and lifelong health advantages and risks

Multiple Polymorphisms Affect Expression and Function of the Neuropeptide S Receptor (NPSR1)

Peer reviewe