Coupling architecture between INS/GPS for precise navigation on set paths

GPS offers the advantage of providing high long-term position accuracy with residual errors that affect the final positioning solution to a few meters with a sampling frequency of 1 Hz (Marston et al. in Decis Support Syst 51:176–189, 2011 [1]). The signals are also subject to obstruction and interference, so GPS receivers cannot be relied upon for a continuous navigation solution. On the contrary, the inertial navigation system has a sampling frequency of at least 50 Hz and exhibits low noise in the short term. In this research, a prototype based on development cards is implemented for the coupling of the inertial navigation system with GPS to improve the precision of navigation on a trajectory

Servicio de entrenamiento en técnicas reproductivas en rumiantes menores: una experiencia de 30 años que continúa. Comunicación

Publicado en: Revista Argentina de Producción Animal. Vol. 42 (Sup. 1) : 10 (2022). Enseñanza Extensión y Vinculación. EEV 10Desde el año 1990, el Grupo de Reproducción y Genética del INTA Bariloche ha realizado, en forma continua, cursos de entrenamiento en técnicas reproductivas para ovinos y caprinos en las temáticas de congelamiento seminal, sincronización de celos, inseminación artificial y transferencia y vitrificación de embriones. Estos cursos están destinados a estudiantes universitarios avanzados, profesionales del sector privado, personal idóneo de establecimientos agropecuarios, profesores universitarios y de escuelas agropecuarias, así como profesionales de organismos públicos (Ley Caprina, Ente de la Región Sur de Río Negro, Dirección de Agricultura y Ganadería del Neuquén, Programa Social Agropecuario, Cambio Rural de las diversas regiones del país y personal profesional de distintas Estaciones Experimentales del INTA).Estación Experimental Agropecuaria BarilocheFil: Cueto, Marcela Isabel. Instituto Nacional de Tecnologia Agropecuaria (INTA). Estacion Experimental Agropecuaria Bariloche. Area Produccion Animal; ArgentinaFil: Bruno Galarraga, María Macarena. Instituto Nacional de Tecnologia Agropecuaria (INTA). Estacion Experimental Agropecuaria Bariloche. Area Produccion Animal; ArgentinaFil: Fernandez, Jimena. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Bariloche. Area Produccion Animal; ArgentinaFil: Fernandez, Jimena. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias; ArgentinaFil: Lopez, Patricia Elisabet. Instituto Nacional de Tecnologia Agropecuaria (INTA). Estacion Experimental Agropecuaria Bariloche. Area Produccion Animal; ArgentinaFil: Giovannini, Nicolas. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Bariloche. Area Produccion Animal; ArgentinaFil: Gibbons, Alejandro Eduardo. Instituto Nacional de Tecnologia Agropecuaria (INTA). Estacion Experimental Agropecuaria Bariloche. Area Produccion Animal. Grupo de Reproducción y Genética; Argentin

Search for dark matter produced in association with bottom or top quarks in √s = 13 TeV pp collisions with the ATLAS detector

A search for weakly interacting massive particle dark matter produced in association with bottom or top quarks is presented. Final states containing third-generation quarks and miss- ing transverse momentum are considered. The analysis uses 36.1 fb−1 of proton–proton collision data recorded by the ATLAS experiment at √s = 13 TeV in 2015 and 2016. No significant excess of events above the estimated backgrounds is observed. The results are in- terpreted in the framework of simplified models of spin-0 dark-matter mediators. For colour- neutral spin-0 mediators produced in association with top quarks and decaying into a pair of dark-matter particles, mediator masses below 50 GeV are excluded assuming a dark-matter candidate mass of 1 GeV and unitary couplings. For scalar and pseudoscalar mediators produced in association with bottom quarks, the search sets limits on the production cross- section of 300 times the predicted rate for mediators with masses between 10 and 50 GeV and assuming a dark-matter mass of 1 GeV and unitary coupling. Constraints on colour- charged scalar simplified models are also presented. Assuming a dark-matter particle mass of 35 GeV, mediator particles with mass below 1.1 TeV are excluded for couplings yielding a dark-matter relic density consistent with measurements

Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

Abstract Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries

Suplementación energético-proteica pre y post destete en crías de cabras Angora

El objetivo de este estudio fue evaluar el efecto de la suplementación energético-proteica en crías Angora sobre: - Peso y Condición corporal en el pre y post destete - Producción de Mohair a la primera y segunda esquila - Capacidad de servicio de los machos a los 17 meses de edadEstación Experimental Agropecuaria BarilocheFil: Bruno Galarraga, María Macarena. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Bariloche. Laboratorio de Reproducción de Rumiantes Menores; ArgentinaFil: Cueto, Marcela Isabel. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Bariloche. Laboratorio de Reproducción de Rumiantes Menores; ArgentinaFil: Giovannini, Nicolas. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Bariloche; ArgentinaFil: Fernández, Jimena. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Bariloche. Laboratorio de Reproducción de Rumiantes Menores; ArgentinaFil: Gibbons, Alejandro Eduardo. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Bariloche. Área de Producción Animal. Laboratorio de Reproducción de Rumiantes Menores; ArgentinaFil: Villar, Maria Laura. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Bariloche; ArgentinaFil: Villagra, Edgar Sebastián. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Bariloche; Argentin

Murine and Non-Human Primate Dendritic Cell Targeting Nanoparticles for <i>in Vivo</i> Generation of Regulatory T‑Cells

Porous silicon nanoparticles (pSiNP), modified to target dendritic cells (DC), provide an alternate strategy for the delivery of immunosuppressive drugs. Here, we aimed to develop a DC-targeting pSiNP displaying c-type lectin, dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin (DC-SIGN), and CD11c monoclonal antibodies. The <i>in vivo</i> tracking of these fluorescent DC-targeting nanoparticles was assessed in both C57BL/6 mice and common marmosets (<i>Callithrix jacchus</i>) by intravenous injection (20 mg/kg). Rapamycin and ovalbumin (OVA)_323–339 peptide loaded pSiNP were employed to evaluate their ability to generate murine CD4⁺CD25⁺FoxP3⁺ regulatory T-cells <i>in vivo</i> within OVA sensitized mice. <i>In vivo,</i> pSiNP migrated to the liver, kidneys, lungs, and spleen in both mice and marmosets. Flow cytometry confirmed pSiNP uptake by splenic and peripheral blood DC when functionalized with targeting antibodies. C57BL/6 OVA sensitized mice injected with CD11c-pSiNP loaded with rapamycin + OVA_323–339 produced a 5-fold higher number of splenic regulatory T-cells compared to control mice, at 40 days post-pSiNP injection. These results demonstrate the importance of the immobilized targeting antibodies to enhance cellular uptake and enable the <i>in vivo</i> generation of splenic regulatory T-cells