Assessment of Sustainable Development

The objective of this paper is to introduce fuzzy set theory and develop fuzzy mathematical models to assess sustainable development based on context-dependent economic, ecological, and societal sustainability indicators. Membership functions are at the core of fuzzy models, and define the degree to which indicators contribute to development. Although a decision-making process regarding sustainable development is subjective, fuzzy set theory links human expectations about development, expressed in linguistic propositions, to numerical data, expressed in measurements of sustainability indicators. In the future, practical implementation of such models will be based on elicitation of expert knowledge to construct a membership function. The fuzzy models developed in this paper provide a novel approach to support decisions regarding sustainable development.agriculture;assessment;fuzzy set theory;sustainable development

Eliciting Expert Knowledge for Fuzzy Evaluation of Agricultural Production Systems

Public concern nowadays is an important frame of reference for thedevelopment of agricultural production systems. The development ofsuch systems, therefore, involves both society level and productionsystem level. Following Zadeh's principle of incompatibility,information obtained at production system level is interpreted atsociety level in linguistic terms. Fuzzy models promise to be avaluable tool as they link measurable information to linguisticinterpretation using membership functions. The objective of this paperis to outline a procedure which deals with criticism regarding theinherent subjectivity in the construction of membership functions whenusing expert knowledge. The procedure guarantees the selection ofappropriate expert knowledge, and provides a guideline supporting theselection of methods to elicit expert knowledge and constructmembership functions. Also on the basis of the results in anillustrative example, it is concluded that the procedure outlined inthis paper suitably deals with criticism regarding membershipfunctions and, therefore, enables a practical implementation of fuzzyevaluation of agricultural production systems. Current researchimplements the procedure to build a fuzzy model which evaluates eggproduction systems in relation to public concern about the welfare oflaying hens.evaluation;subjectivity;expert knowledge;fuzzy models;knowledge elicitation

Assessment of Sustainable Development

The objective of this paper is to introduce fuzzy set theory and develop fuzzy mathematical models to assess sustainable development based on context-dependent economic, ecological, and societal sustainability indicators. Membership functions are at the core of fuzzy models, and define the degree to which indicators contribute to development. Although a decision-making process regarding sustainable development is subjective, fuzzy set theory links human expectations about development, expressed in linguistic propositions, to numerical data, expressed in measurements of sustainability indicators. In the future, practical implementation of such models will be based on elicitation of expert knowledge to construct a membership function. The fuzzy models developed in this paper provide a novel approach to support decisions regarding sustainable development

Eliciting Expert Knowledge for Fuzzy Evaluation of Agricultural Production Systems

Public concern nowadays is an important frame of reference for the development of agricultural production systems. The development of such systems, therefore, involves both society level and production system level. Following Zadeh's principle of incompatibility, information obtained at production system level is interpreted at society level in linguistic terms. Fuzzy models promise to be a valuable tool as they link measurable information to linguistic interpretation using membership functions. The objective of this paper is to outline a procedure which deals with criticism regarding the inherent subjectivity in the construction of membership functions when using expert knowledge. The procedure guarantees the selection of appropriate expert knowledge, and provides a guideline supporting the selection of methods to elicit expert knowledge and construct membership functions. Also on the basis of the results in an illustrative example, it is concluded that the procedure outlined in this paper suitably deals with criticism regarding membership functions and, therefore, enables a practical implementation of fuzzy evaluation of agricultural production systems. Current research implements the procedure to build a fuzzy model which evaluates egg production systems in relation to public concern about the welfare of laying hens

Diffusion profile of macromolecules within and between human skin layers for (trans)dermal drug delivery

Delivering a drug into and through the skin is of interest as the skin can act as an alternative drug administration route for oral delivery. The development of new delivery methods, such as microneedles, makes it possible to not only deliver small molecules into the skin, which are able to pass the outer layer of the skin in therapeutic amounts, but also macromolecules. To provide insight into the administration of these molecules into the skin, the aim of this study was to assess the transport of macromolecules within and between its various layers. The diffusion coefficients in the epidermis and several locations in the papillary and reticular dermis were determined for fluorescein dextran of 40 and 500 kDa using a combination of fluorescent recovery after photobleaching experiments and finite element analysis. The diffusion coefficient was significantly higher for 40 kDa than 500 kDa dextran, with median values of 23 and 9 µm2/s in the dermis, respectively. The values only marginally varied within and between papillary and reticular dermis. For the 40 kDa dextran, the diffusion coefficient in the epidermis was twice as low as in the dermis layers. The adopted method may be used for other macromolecules, which are of interest for dermal and transdermal drug delivery. The knowledge about diffusion in the skin is useful to optimize (trans)dermal drug delivery systems to target specific layers or cells in the human skin

Jet size dependence of single jet suppression in lead-lead collisions at sqrt(s(NN)) = 2.76 TeV with the ATLAS detector at the LHC

Measurements of inclusive jet suppression in heavy ion collisions at the LHC provide direct sensitivity to the physics of jet quenching. In a sample of lead-lead collisions at sqrt(s) = 2.76 TeV corresponding to an integrated luminosity of approximately 7 inverse microbarns, ATLAS has measured jets with a calorimeter over the pseudorapidity interval |eta| < 2.1 and over the transverse momentum range 38 < pT < 210 GeV. Jets were reconstructed using the anti-kt algorithm with values for the distance parameter that determines the nominal jet radius of R = 0.2, 0.3, 0.4 and 0.5. The centrality dependence of the jet yield is characterized by the jet "central-to-peripheral ratio," Rcp. Jet production is found to be suppressed by approximately a factor of two in the 10% most central collisions relative to peripheral collisions. Rcp varies smoothly with centrality as characterized by the number of participating nucleons. The observed suppression is only weakly dependent on jet radius and transverse momentum. These results provide the first direct measurement of inclusive jet suppression in heavy ion collisions and complement previous measurements of dijet transverse energy imbalance at the LHC.Comment: 15 pages plus author list (30 pages total), 8 figures, 2 tables, submitted to Physics Letters B. All figures including auxiliary figures are available at http://atlas.web.cern.ch/Atlas/GROUPS/PHYSICS/PAPERS/HION-2011-02

Search for direct production of charginos and neutralinos in events with three leptons and missing transverse momentum in √s = 7 TeV pp collisions with the ATLAS detector

A search for the direct production of charginos and neutralinos in final states with three electrons or muons and missing transverse momentum is presented. The analysis is based on 4.7 fb−1 of proton–proton collision data delivered by the Large Hadron Collider and recorded with the ATLAS detector. Observations are consistent with Standard Model expectations in three signal regions that are either depleted or enriched in Z-boson decays. Upper limits at 95% confidence level are set in R-parity conserving phenomenological minimal supersymmetric models and in simplified models, significantly extending previous results

Search for displaced vertices arising from decays of new heavy particles in 7 TeV pp collisions at ATLAS

We present the results of a search for new, heavy particles that decay at a significant distance from their production point into a final state containing charged hadrons in association with a high-momentum muon. The search is conducted in a pp-collision data sample with a center-of-mass energy of 7 TeV and an integrated luminosity of 33 pb^-1 collected in 2010 by the ATLAS detector operating at the Large Hadron Collider. Production of such particles is expected in various scenarios of physics beyond the standard model. We observe no signal and place limits on the production cross-section of supersymmetric particles in an R-parity-violating scenario as a function of the neutralino lifetime. Limits are presented for different squark and neutralino masses, enabling extension of the limits to a variety of other models.Comment: 8 pages plus author list (20 pages total), 8 figures, 1 table, final version to appear in Physics Letters

Measurement of the polarisation of W bosons produced with large transverse momentum in pp collisions at sqrt(s) = 7 TeV with the ATLAS experiment

This paper describes an analysis of the angular distribution of W->enu and W->munu decays, using data from pp collisions at sqrt(s) = 7 TeV recorded with the ATLAS detector at the LHC in 2010, corresponding to an integrated luminosity of about 35 pb^-1. Using the decay lepton transverse momentum and the missing transverse energy, the W decay angular distribution projected onto the transverse plane is obtained and analysed in terms of helicity fractions f0, fL and fR over two ranges of W transverse momentum (ptw): 35 < ptw < 50 GeV and ptw > 50 GeV. Good agreement is found with theoretical predictions. For ptw > 50 GeV, the values of f0 and fL-fR, averaged over charge and lepton flavour, are measured to be : f0 = 0.127 +/- 0.030 +/- 0.108 and fL-fR = 0.252 +/- 0.017 +/- 0.030, where the first uncertainties are statistical, and the second include all systematic effects.Comment: 19 pages plus author list (34 pages total), 9 figures, 11 tables, revised author list, matches European Journal of Physics C versio

Observation of a new chi_b state in radiative transitions to Upsilon(1S) and Upsilon(2S) at ATLAS

The chi_b(nP) quarkonium states are produced in proton-proton collisions at the Large Hadron Collider (LHC) at sqrt(s) = 7 TeV and recorded by the ATLAS detector. Using a data sample corresponding to an integrated luminosity of 4.4 fb^-1, these states are reconstructed through their radiative decays to Upsilon(1S,2S) with Upsilon->mu+mu-. In addition to the mass peaks corresponding to the decay modes chi_b(1P,2P)->Upsilon(1S)gamma, a new structure centered at a mass of 10.530+/-0.005 (stat.)+/-0.009 (syst.) GeV is also observed, in both the Upsilon(1S)gamma and Upsilon(2S)gamma decay modes. This is interpreted as the chi_b(3P) system.Comment: 5 pages plus author list (18 pages total), 2 figures, 1 table, corrected author list, matches final version in Physical Review Letter