749 research outputs found
Investigation of Temperature Effects into Long-Span Bridges via Hybrid Sensing and Supervised Regression Models
Temperature is an important environmental factor for long-span bridges because it induces thermal loads on structural components that cause considerable displacements, stresses, and structural damage. Hence, it is critical to acquire up-to-date information on the status, sustainability, and serviceability of long-span bridges under daily and seasonal temperature fluctuations. This paper intends to investigate the effects of temperature variability on structural displacements obtained from remote sensing and represent their relationship using supervised regression models. In contrast to other studies in this field, one of the contributions of this paper is to leverage hybrid sensing as a combination of contact and non-contact sensors for measuring temperature data and structural responses. Apart from temperature, other unmeasured environmental and operational conditions may affect structural displacements of long-span bridges separately or simultaneously. For this issue, this paper incorporates a correlation analysis between the measured predictor (temperature) and response (displacement) data using a linear correlation measure, the Pearson correlation coefficient, as well as nonlinear correlation measures, namely the Spearman and Kendall correlation coefficients and the maximal information criterion, to determine whether the measured environmental factor is dominant or other unmeasured conditions affect structural responses. Finally, three supervised regression techniques based on a linear regression model, Gaussian process regression, and support vector regression are considered to model the relationship between temperature and structural displacements and to conduct the prediction process. Temperature and limited displacement data related to three long-span bridges are used to demonstrate the results of this research. The aim of this research is to assess and realize whether contact-based sensors installed in a bridge structure for measuring environmental and/or operational factors are sufficient or if it is necessary to consider further sensors and investigations
Impact of climate changes on water resources availability in the Orontes River Watershed: case of Homs Governorate in Syria
The role of extracellular polymers on Staphylococcus epidermidis biofilm biomass and metabolic activity
Staphylococcus epidermidis is now well established as being a major nosocomial
pathogen, associated with indwelling medical devices. Its major virulence factor is related with
the ability to adhere to indwelling medical devices, with consequent biofilm formation.
The present study aimed to evaluate the role of polysaccharides and proteins on
biofilm biomass and metabolic activity of five S. epidermidis clinical isolates. For this purpose,
S. epidermis biofilms, formed on acrylic coupons, were characterized in terms of total biofilm
biomass, determined through crystal violet assay, cell concentration, established by colony
forming units (CFU) enumeration, and biofilm matrix composition, which was assessed for
polysaccharides and proteins content. Biofilm metabolic activity was evaluated by two distinct
methods: glucose uptake and XTT reduction assays. According to the results, S. epidermidis
strains revealed different abilities for biofilm formation. In fact, some strains were able to form
thicker biofilms than others and this is important because biofilm formation is considered one
of the major virulence factors of S. epidermidis species. S. epidermidis 1457 was the strain that
produced the larger amount of biofilm and strain LE7 was the lowest biofilm producer, and
these were also the highest and the lowest polysaccharides producers, respectively. This
suggests a certain degree of correlation between exopolysaccharides production and total
amount of biomass formed. Besides, comparing the results obtained, in terms of
exopolysaccharides production and biofilm cellular activity, it seems clear that a strong
production of exopolysaccharides can lead to a decrease in the metabolic activity of cells,
which was the case of S. epidermidis 1457. The protein concentration also varied among
strains, with the biofilm matrix of S. epidermidis 9142 presenting a higher concentration of
proteins comparing to the remaining strains. This fact indicates the different levels of
importance that matrix proteins can have on biofilm composition among strains albeit overall,
it is suggested that extracellular protein production it is not a determinant factor for biofilm
total biomass, despite its qualitative value.
In conclusion, this work provided a reliable approach for a better understanding of S.
epidermidis biofilms composition and metabolic activity
Blockade of Toll-like receptor 2 prevents spontaneous cytokine release from rheumatoid arthritis ex vivo synovial explant cultures
STELLAR: fast and exact local alignments
<p>Abstract</p> <p>Background</p> <p>Large-scale comparison of genomic sequences requires reliable tools for the search of local alignments. Practical local aligners are in general fast, but heuristic, and hence sometimes miss significant matches.</p> <p>Results</p> <p>We present here the local pairwise aligner STELLAR that has full sensitivity for <it>Δ</it>-alignments, i.e. guarantees to report all local alignments of a given minimal length and maximal error rate. The aligner is composed of two steps, filtering and verification. We apply the SWIFT algorithm for lossless filtering, and have developed a new verification strategy that we prove to be exact. Our results on simulated and real genomic data confirm and quantify the conjecture that heuristic tools like BLAST or BLAT miss a large percentage of significant local alignments.</p> <p>Conclusions</p> <p>STELLAR is very practical and fast on very long sequences which makes it a suitable new tool for finding local alignments between genomic sequences under the edit distance model. Binaries are freely available for Linux, Windows, and Mac OS X at <url>http://www.seqan.de/projects/stellar</url>. The source code is freely distributed with the SeqAn C++ library version 1.3 and later at <url>http://www.seqan.de</url>.</p
Measurement of the cross-section of high transverse momentum vector bosons reconstructed as single jets and studies of jet substructure in pp collisions at âs = 7 TeV with the ATLAS detector
This paper presents a measurement of the cross-section for high transverse momentum W and Z bosons produced in pp collisions and decaying to all-hadronic final states. The data used in the analysis were recorded by the ATLAS detector at the CERN Large Hadron Collider at a centre-of-mass energy of âs = 7 TeV;{\rm Te}{\rm V}4.6\;{\rm f}{{{\rm b}}^{-1}}{{p}_{{\rm T}}}\gt 320\;{\rm Ge}{\rm V}|\eta |\lt 1.9{{\sigma }_{W+Z}}=8.5\pm 1.7$ pb and is compared to next-to-leading-order calculations. The selected events are further used to study jet grooming techniques
Search for direct pair production of the top squark in all-hadronic final states in proton-proton collisions at sâ=8 TeV with the ATLAS detector
The results of a search for direct pair production of the scalar partner to the top quark using an integrated luminosity of 20.1fbâ1 of protonâproton collision data at âs = 8 TeV recorded with the ATLAS detector at the LHC are reported. The top squark is assumed to decay via tËâtÏË01 or tËâ bÏ˱1 âbW(â)ÏË01 , where ÏË01 (Ï˱1 ) denotes the lightest neutralino (chargino) in supersymmetric models. The search targets a fully-hadronic final state in events with four or more jets and large missing transverse momentum. No significant excess over the Standard Model background prediction is observed, and exclusion limits are reported in terms of the top squark and neutralino masses and as a function of the branching fraction of tË â tÏË01 . For a branching fraction of 100%, top squark masses in the range 270â645 GeV are excluded for ÏË01 masses below 30 GeV. For a branching fraction of 50% to either tË â tÏË01 or tË â bÏ˱1 , and assuming the Ï˱1 mass to be twice the ÏË01 mass, top squark masses in the range 250â550 GeV are excluded for ÏË01 masses below 60 GeV
Search for pair-produced long-lived neutral particles decaying to jets in the ATLAS hadronic calorimeter in ppcollisions at âs=8TeV
The ATLAS detector at the Large Hadron Collider at CERN is used to search for the decay of a scalar boson to a pair of long-lived particles, neutral under the Standard Model gauge group, in 20.3fbâ1of data collected in protonâproton collisions at âs=8TeV. This search is sensitive to long-lived particles that decay to Standard Model particles producing jets at the outer edge of the ATLAS electromagnetic calorimeter or inside the hadronic calorimeter. No significant excess of events is observed. Limits are reported on the product of the scalar boson production cross section times branching ratio into long-lived neutral particles as a function of the proper lifetime of the particles. Limits are reported for boson masses from 100 GeVto 900 GeV, and a long-lived neutral particle mass from 10 GeVto 150 GeV
Cost-Effective Joint Echo-NEXT Canceller Designs for 10GBase-T Ethernet Systems Based on a Shortened Impulse Response Filter (SIRF) Scheme
An update of the Worldwide Integrated Assessment (WIA) on systemic insecticides. Part 2: impacts on organisms and ecosystems
New information on the lethal and sublethal effects of neonicotinoids and fipronil on organisms is presented in this review, complementing the previous WIA in 2015. The high toxicity of these systemic insecticides to invertebrates has been confirmed and expanded to include more species and compounds. Most of the recent research has focused on bees and the sublethal and ecological impacts these insecticides have on pollinators. Toxic effects on other invertebrate taxa also covered predatory and parasitoid natural enemies and aquatic arthropods. Little, while not much new information has been gathered on soil organisms. The impact on marine coastal ecosystems is still largely uncharted. The chronic lethality of neonicotinoids to insects and crustaceans, and the strengthened evidence that these chemicals also impair the immune system and reproduction, highlights the dangers of this particular insecticidal classneonicotinoids and fipronil. , withContinued large scale â mostly prophylactic â use of these persistent organochlorine pesticides has the potential to greatly decreasecompletely eliminate populations of arthropods in both terrestrial and aquatic environments. Sublethal effects on fish, reptiles, frogs, birds and mammals are also reported, showing a better understanding of the mechanisms of toxicity of these insecticides in vertebrates, and their deleterious impacts on growth, reproduction and neurobehaviour of most of the species tested. This review concludes with a summary of impacts on the ecosystem services and functioning, particularly on pollination, soil biota and aquatic invertebrate communities, thus reinforcing the previous WIA conclusions (van der Sluijs et al. 2015)
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