Synthesis and Characterization of copper oxide(II) nanoparticles prepared by hydrothermal process

تم استخدام طريقة الهدرجة الحرارية لتحضير جسيمات اوكسيد النحاس النانوية , يمكن تحضير جسيمات النحاس النانوية بدون استخدام المذيبات العضوية او مواد غالية الثمن بأستخدام الهدرجة الحرارية. حيود الاشعة السينية أكد بان جسيمات النحاس النانوية ذات تركيب احادي الميل , مع حجم حبيبي 20nm , كما ان التحليل بأستخدام مجهر القوة الذرية اوضح بأن قطر الحجم الحبيبي هو في ضمن المدى النانوي . التحليل بواسطة طيف ( FTIR )اكدت لنا بأن التركيب هو اوكسيد النحاس كما ان خصائص نمط الاهتزاز لأوكسجين-  نحاس تم تأكيده. تم دراسة الخواص البصرية بأستخدام الطيف المرئي للاشعة فوق البنفسجية والتي اوضحت بأن جسيمات النحاس تمتلك انحراف بأتجاه المنطقة المسماة (blue shift) , حيث تمتلك فجوة عالية طاقة (  (4.9eV, وان هذا ربما يعود الى تأثير الحصر الكمي لجسيمات اوكسيد النحاس النانوية.Hydrothermal process was  used to prepare CuO nanoparticles. CuO nanoparticles can be prepare without organic solvents, expensive raw materials by a hydrothermal method. XRD diffraction reveals that CuO nanoparticles have a monoclinic structure with particle size 20nm ,  and AFM analysis showed that the diameter of the Grain size is in a nanometer range. The analysis by FTIR spectra assure that the composition was CuO, and the  features of vibrational types of Cu–O were fixed. also the optical properties was analysed with UV–vis showed that  CuO nano particles have considerable a blue shift  , which have aband gab equal to (4.9 eV ) , and this is because the effect of quntum confienment of prepared CuO nano particles

Synthesis and Characterization of copper oxide(II) nanoparticles prepared by hydrothermal process

تم استخدام طريقة الهدرجة الحرارية لتحضير جسيمات اوكسيد النحاس النانوية , يمكن تحضير جسيمات النحاس النانوية بدون استخدام المذيبات العضوية او مواد غالية الثمن بأستخدام الهدرجة الحرارية. حيود الاشعة السينية أكد بان جسيمات النحاس النانوية ذات تركيب احادي الميل , مع حجم حبيبي 20nm , كما ان التحليل بأستخدام مجهر القوة الذرية اوضح بأن قطر الحجم الحبيبي هو في ضمن المدى النانوي . التحليل بواسطة طيف ( FTIR )اكدت لنا بأن التركيب هو اوكسيد النحاس كما ان خصائص نمط الاهتزاز لأوكسجين-  نحاس تم تأكيده. تم دراسة الخواص البصرية بأستخدام الطيف المرئي للاشعة فوق البنفسجية والتي اوضحت بأن جسيمات النحاس تمتلك انحراف بأتجاه المنطقة المسماة (blue shift) , حيث تمتلك فجوة عالية طاقة (  (4.9eV, وان هذا ربما يعود الى تأثير الحصر الكمي لجسيمات اوكسيد النحاس النانوية.     Hydrothermal process was  used to prepare CuO nanoparticles. CuO nanoparticles can be prepare without organic solvents, expensive raw materials by a hydrothermal method. XRD diffraction reveals that CuO nanoparticles have a monoclinic structure with particle size 20nm ,  and AFM analysis showed that the diameter of the Grain size is in a nanometer range. The analysis by FTIR spectra assure that the composition was CuO, and the  features of vibrational types of Cu–O were fixed. also the optical properties was analysed with UV–vis showed that  CuO nano particles have considerable a blue shift  , which have aband gab equal to (4.9 eV ) , and this is because the effect of quntum confienment of prepared CuO nano particles

Purchase of prescription and OTC medicines in Slovakia: factors influencing patients' expectations and satisfaction

ABSTRACT Slovakia is a country where the purchase of OTC (over the counter) medicines outside the pharmacy is not allowed by the government. This study aimed at evaluating patients' satisfaction and acceptance of community pharmacists. Customer's behaviour and expectations influencing the purchase of prescription and OTC medicines were analyzed. A structured questionnaire having 15 multiple-choice questions was used to analyze the descriptive parameters. Data collection lasted from January to February 2014. The sample size consisted of 357 high-school educated individuals under 40 years of age. The survey showed that the prescription and OTC medicines were bought equally. The participants reported a 96.0%, 96.3% and 90.2% satisfaction rate with willingness and approach of the community pharmacist, pharmacy services and provision of drug information respectively. As for the OTC medicines, 89.5% people considered the pharmacist an expert: 88.2% purchased medicines with pharmacist's recommendation, 97.8% needed a professional counselling and 97.2% required a pharmacist's guidance. As for the prescription drugs, only 72.1% considered the pharmacist an expert: 96.3% suggested that physician's prescription was significant and 88.3% considered pharmacist's guidance in the process of selection of prescription medicines nonessential. A comprehensible and respectable conversation was highly expected in regards to both the OTC and prescription medicines

A Helicity-Based Method to Infer the CME Magnetic Field Magnitude in Sun and Geospace: Generalization and Extension to Sun-Like and M-Dwarf Stars and Implications for Exoplanet Habitability

Patsourakos et al. (Astrophys. J. 817, 14, 2016) and Patsourakos and Georgoulis (Astron. Astrophys. 595, A121, 2016) introduced a method to infer the axial magnetic field in flux-rope coronal mass ejections (CMEs) in the solar corona and farther away in the interplanetary medium. The method, based on the conservation principle of magnetic helicity, uses the relative magnetic helicity of the solar source region as input estimates, along with the radius and length of the corresponding CME flux rope. The method was initially applied to cylindrical force-free flux ropes, with encouraging results. We hereby extend our framework along two distinct lines. First, we generalize our formalism to several possible flux-rope configurations (linear and nonlinear force-free, non-force-free, spheromak, and torus) to investigate the dependence of the resulting CME axial magnetic field on input parameters and the employed flux-rope configuration. Second, we generalize our framework to both Sun-like and active M-dwarf stars hosting superflares. In a qualitative sense, we find that Earth may not experience severe atmosphere-eroding magnetospheric compression even for eruptive solar superflares with energies ~ 10^4 times higher than those of the largest Geostationary Operational Environmental Satellite (GOES) X-class flares currently observed. In addition, the two recently discovered exoplanets with the highest Earth-similarity index, Kepler 438b and Proxima b, seem to lie in the prohibitive zone of atmospheric erosion due to interplanetary CMEs (ICMEs), except when they possess planetary magnetic fields that are much higher than that of Earth.Comment: http://adsabs.harvard.edu/abs/2017SoPh..292...89

An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics

For a decade, The Cancer Genome Atlas (TCGA) program collected clinicopathologic annotation data along with multi-platform molecular profiles of more than 11,000 human tumors across 33 different cancer types. TCGA clinical data contain key features representing the democratized nature of the data collection process. To ensure proper use of this large clinical dataset associated with genomic features, we developed a standardized dataset named the TCGA Pan-Cancer Clinical Data Resource (TCGA-CDR), which includes four major clinical outcome endpoints. In addition to detailing major challenges and statistical limitations encountered during the effort of integrating the acquired clinical data, we present a summary that includes endpoint usage recommendations for each cancer type. These TCGA-CDR findings appear to be consistent with cancer genomics studies independent of the TCGA effort and provide opportunities for investigating cancer biology using clinical correlates at an unprecedented scale. Analysis of clinicopathologic annotations for over 11,000 cancer patients in the TCGA program leads to the generation of TCGA Clinical Data Resource, which provides recommendations of clinical outcome endpoint usage for 33 cancer types

Driver Fusions and Their Implications in the Development and Treatment of Human Cancers.

Gene fusions represent an important class of somatic alterations in cancer. We systematically investigated fusions in 9,624 tumors across 33 cancer types using multiple fusion calling tools. We identified a total of 25,664 fusions, with a 63% validation rate. Integration of gene expression, copy number, and fusion annotation data revealed that fusions involving oncogenes tend to exhibit increased expression, whereas fusions involving tumor suppressors have the opposite effect. For fusions involving kinases, we found 1,275 with an intact kinase domain, the proportion of which varied significantly across cancer types. Our study suggests that fusions drive the development of 16.5% of cancer cases and function as the sole driver in more than 1% of them. Finally, we identified druggable fusions involving genes such as TMPRSS2, RET, FGFR3, ALK, and ESR1 in 6.0% of cases, and we predicted immunogenic peptides, suggesting that fusions may provide leads for targeted drug and immune therapy

Search for leptophobic Z ' bosons decaying into four-lepton final states in proton-proton collisions at root s=8 TeV

Peer reviewe

Search for black holes and other new phenomena in high-multiplicity final states in proton-proton collisions at root s=13 TeV

Peer reviewe

Measurements of differential production cross sections for a Z boson in association with jets in pp collisions at root s=8 TeV

Peer reviewe