244 research outputs found

    Análisis del efecto de la tributación sobre la competitividad de los países

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    En este estudio se hace una revisión bibliográfica de las diferentes aproximaciones a la definición de competitividad, de tributación y a la relación que existe entre estos dos conceptos, para posteriormente realizar una relación empírica de los mismos -- A diferencia de otros estudios, la competitividad se analiza a partir de la Productividad Total de los Factores (PTF) y la tributación no se unifica en un único índice, sino que se descompone en sus tres principales variables: número de pagos, tiempo requerido para pagar impuestos y tasa total de impuestos sobre ganancias comerciales -- El análisis estadístico realizado sugiere la existencia de una correlación entre la competitividad (medida como PTF) y la tasa de impuestos sobre las ganancias comerciales, además de mostrar que esta correlación es negativa -- Adicionalmente, muestra que el efecto de la tributación sobre la competitividad es contemporáneo -- Las otras dos variables tributarias no mostraron correlación alguna con la PT

    Quantification of anaerobic cellulolytic bacteria from the rumen of cattle : comparison of three techniques

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    ABSTRACT: Rumen microorganisms are responsible for digestion of plants material consumed by ruminants. Cellulolytic bacteria have the ability to degrade structural carbohydrates, so the abundance and enzymatic activity of these is essential for developing strategies to manipulate the rumen fermentation. Objective Compare the methods for quantification of bacterial growth: most probable number, viable cell count and Roll-tube plate for enumeration of rumen bacteria. Materials and methods Comparative experimental study. We evaluated three methods for quantification of bacterial growth: most probable number, viable cell count and Roll-tube plate with respect to the density and diversity of ruminal cellulolytic bacteria in rumen fluid samples collected from two cannulated Holstein females to rumen. Results High and positive correlation was observed with statistical significance (0.826; p=0.000) between the quantification of viable cells by the Roll Tube method and the plaque viable cells quantification method. Another correlation, this time negative, moderated and weak, was observed between the quantification of viable cells obtained by the “most probable number” method with the Roll Tube method and the plaque method too. (-0.514; p=0.237;-0.374; p=0.147 respectively). The results from the determination coefficient corroborate this information. On the one hand, the “most probable number” method detected low diversity, on the other hand the other methods (Roll Tube and plaque), demonstrated consistency with regard to density and bacteria diversity. Conclusions The data suggest that the technique of counting viable cells in plaque may be most appropriate to quantify ruminal cellulolytic bacteria.RESUMEN: Los microorganismos del rumen son los responsables de la digestión del material vegetal que consumen los rumiantes. Las bacterias celulolíticas poseen la capacidad de degradar carbohidratos estructurales, por lo cual la abundancia y actividad enzimática de éstas es esencial para la formulación de estrategias de manipulación de la fermentación ruminal. Objetivo Comparar los métodos de cuantificación de crecimiento bacteriano: número más probable, recuento de células viables en placa y Roll-tube para la enumeración de bacterias celulolíticas del rumen. Materiales y métodos Estudio experimental comparativo. Se evaluaron tres métodos de cuantificación de crecimiento bacteriano: número más probable, recuento de células viables en placa y Roll-tube, con respecto a la densidad y diversidad de bacterias celulolíticas ruminales en muestras de contenido ruminal recolectadas de dos hembras de raza Holstein canuladas al rumen. Resultados Se observó correlación positiva, de tipo alta con significancia estadística (0,826; p = 0,000) entre la cuantificación de células viables por el método de Roll-Tube y la cuantificación en placa, y una correlación negativa y de tipo moderada débil entre la cuantificación de células viables obtenidas por el método del número más probable con el método Roll-Tube (-0,514; p = 0,237), y negativa y de tipo débil entre la cuantificación con el método de número más probable y recuento en placa (-0,374; p = 0,147). Los resultados del coeficiente de determinación corroboran este dato. Con el número más probable se detectó baja diversidad, mientras que los métodos de recuento de células viables en placa y Roll-Tube mostraron consistencia respecto a densidad y diversidad de bacterias. Conclusiones Los resultados sugieren que la técnica de recuento de células viables en placa puede ser la más adecuada para cuantificar bacterias celulolíticas ruminales

    Treatment with tocilizumab or corticosteroids for COVID-19 patients with hyperinflammatory state: a multicentre cohort study (SAM-COVID-19)

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    Objectives: The objective of this study was to estimate the association between tocilizumab or corticosteroids and the risk of intubation or death in patients with coronavirus disease 19 (COVID-19) with a hyperinflammatory state according to clinical and laboratory parameters. Methods: A cohort study was performed in 60 Spanish hospitals including 778 patients with COVID-19 and clinical and laboratory data indicative of a hyperinflammatory state. Treatment was mainly with tocilizumab, an intermediate-high dose of corticosteroids (IHDC), a pulse dose of corticosteroids (PDC), combination therapy, or no treatment. Primary outcome was intubation or death; follow-up was 21 days. Propensity score-adjusted estimations using Cox regression (logistic regression if needed) were calculated. Propensity scores were used as confounders, matching variables and for the inverse probability of treatment weights (IPTWs). Results: In all, 88, 117, 78 and 151 patients treated with tocilizumab, IHDC, PDC, and combination therapy, respectively, were compared with 344 untreated patients. The primary endpoint occurred in 10 (11.4%), 27 (23.1%), 12 (15.4%), 40 (25.6%) and 69 (21.1%), respectively. The IPTW-based hazard ratios (odds ratio for combination therapy) for the primary endpoint were 0.32 (95%CI 0.22-0.47; p < 0.001) for tocilizumab, 0.82 (0.71-1.30; p 0.82) for IHDC, 0.61 (0.43-0.86; p 0.006) for PDC, and 1.17 (0.86-1.58; p 0.30) for combination therapy. Other applications of the propensity score provided similar results, but were not significant for PDC. Tocilizumab was also associated with lower hazard of death alone in IPTW analysis (0.07; 0.02-0.17; p < 0.001). Conclusions: Tocilizumab might be useful in COVID-19 patients with a hyperinflammatory state and should be prioritized for randomized trials in this situatio

    Bose-Einstein correlations of charged hadrons in proton-proton collisions at s\sqrt s = 13 TeV

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    Bose-Einstein correlations of charged hadrons are measured over a broad multiplicity range, from a few particles up to about 250 reconstructed charged hadrons in proton-proton collisions at s \sqrt{s} = 13 TeV. The results are based on data collected using the CMS detector at the LHC during runs with a special low-pileup configuration. Three analysis techniques with different degrees of dependence on simulations are used to remove the non-Bose-Einstein background from the correlation functions. All three methods give consistent results. The measured lengths of homogeneity are studied as functions of particle multiplicity as well as average pair transverse momentum and mass. The results are compared with data from both CMS and ATLAS at s \sqrt{s} = 7 TeV, as well as with theoretical predictions.[graphic not available: see fulltext]Bose-Einstein correlations of charged hadrons are measured over a broad multiplicity range, from a few particles up to about 250 reconstructed charged hadrons in proton-proton collisions at s=\sqrt{s} = 13 TeV. The results are based on data collected using the CMS detector at the LHC during runs with a special low-pileup configuration. Three analysis techniques with different degrees of dependence on simulations are used to remove the non-Bose-Einstein background from the correlation functions. All three methods give consistent results. The measured lengths of homogeneity are studied as functions of particle multiplicity as well as average pair transverse momentum and mass. The results are compared with data from both CMS and ATLAS at s=\sqrt{s} = 7 TeV, as well as with theoretical predictions

    Search for dark matter in events with a leptoquark and missing transverse momentum in proton-proton collisions at 13 TeV

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    A search is presented for dark matter in proton-proton collisions at a center-of-mass energy of root s= 13 TeV using events with at least one high transverse momentum (p(T)) muon, at least one high-p(T) jet, and large missing transverse momentum. The data were collected with the CMS detector at the CERN LHC in 2016 and 2017, and correspond to an integrated luminosity of 77.4 fb(-1). In the examined scenario, a pair of scalar leptoquarks is assumed to be produced. One leptoquark decays to a muon and a jet while the other decays to dark matter and low-p(T) standard model particles. The signature for signal events would be significant missing transverse momentum from the dark matter in conjunction with a peak at the leptoquark mass in the invariant mass distribution of the highest p(T) muon and jet. The data are observed to be consistent with the background predicted by the standard model. For the first benchmark scenario considered, dark matter masses up to 500 GeV are excluded for leptoquark masses m(LQ) approximate to 1400 GeV, and up to 300 GeV for m(LQ) approximate to 1500 GeV. For the second benchmark scenario, dark matter masses up to 600 GeV are excluded for m(LQ) approximate to 1400 GeV. (C) 2019 The Author(s). Published by Elsevier B.V.Peer reviewe

    Measurement of the Splitting Function in &ITpp &ITand Pb-Pb Collisions at root&ITsNN&IT=5.02 TeV

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    Data from heavy ion collisions suggest that the evolution of a parton shower is modified by interactions with the color charges in the dense partonic medium created in these collisions, but it is not known where in the shower evolution the modifications occur. The momentum ratio of the two leading partons, resolved as subjets, provides information about the parton shower evolution. This substructure observable, known as the splitting function, reflects the process of a parton splitting into two other partons and has been measured for jets with transverse momentum between 140 and 500 GeV, in pp and PbPb collisions at a center-of-mass energy of 5.02 TeV per nucleon pair. In central PbPb collisions, the splitting function indicates a more unbalanced momentum ratio, compared to peripheral PbPb and pp collisions.. The measurements are compared to various predictions from event generators and analytical calculations.Peer reviewe

    Search for an L-mu - L-tau gauge boson using Z -> 4 mu events in proton-proton collisions at root s=13 TeV

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    A search for a narrow Z' gauge boson with a mass between 5 and 70 GeV resulting from an L-mu - L-tau U (1) local gauge symmetry is reported. Theories that predict such a particle have been proposed as an explanation of various experimental discrepancies, including the lack of a dark matter signal in direct-detection experiments, tension in the measurement of the anomalous magnetic moment of the muon, and reports of possible lepton flavor universality violation in B meson decays. A data sample of proton-proton collisions at a center-of-mass energy of 13 TeV is used, corresponding to an integrated luminosity of 77.3 fb(-1) recorded in 2016 and 2017 by the CMS detector at the LHC. Events containing four muons with an invariant mass near the standard model Z boson mass are analyzed, and the selection is further optimized to be sensitive to the events that may contain Z -> Z'mu mu -> 4 mu decays. The event yields are consistent with the standard model predictions. Upper limits of 10(-8)-10(-7) at 95% confidence level are set on the product of branching fractions B(Z -> Z'mu mu)B(Z' -> mu mu), depending on the Z' mass, which excludes a Z' boson coupling strength to muons above 0.004-0.3. These are the first dedicated limits on L-mu - L-tau models at the LHC and result in a significant increase in the excluded model parameter space. The results of this search may also be used to constrain the coupling strength of any light Z' gauge boson to muons. (C) 2019 The Author(s). Published by Elsevier B.V.Peer reviewe

    Measurement of electroweak WZ boson production and search for new physics in WZ + two jets events in pp collisions at √s=13TeV

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    A measurement of WZ electroweak (EW) vector boson scattering is presented. The measurement is performed in the leptonic decay modes WZ→ℓνℓ′ℓ′, where ℓ,ℓ′=e,μ. The analysis is based on a data sample of proton-proton collisions at √s=13 TeV at the LHC collected with the CMS detector and corresponding to an integrated luminosity of 35.9 fb−1. The WZ plus two jet production cross section is measured in fiducial regions with enhanced contributions from EW production and found to be consistent with standard model predictions. The EW WZ production in association with two jets is measured with an observed (expected) significance of 2.2 (2.5) standard deviations. Constraints on charged Higgs boson production and on anomalous quartic gauge couplings in terms of dimension-eight effective field theory operators are also presented

    Studies of Beauty Suppression via Nonprompt D-0 Mesons in Pb-Pb Collisions at root s(NN)=5.02 TeV

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    The transverse momentum spectra of D-0 mesons from b hadron decays are measured at midrapidity (vertical bar y vertical bar D-0 yield is found to be suppressed in the measured p(T) range from 2 to 100 GeV/c as compared to pp collisions. The suppression is weaker than that of prompt D-0 mesons and charged hadrons for p(T) around 10 GeV/c. While theoretical calculations incorporating partonic energy loss in the quark-gluon plasma can successfully describe the measured B -> D-0 suppression at higher p(T), the data show an indication of larger suppression than the model predictions in the range of 2 <p(T) <5 GeV/c.Peer reviewe

    Search for new phenomena in final states with two opposite-charge, same-flavor leptons, jets, and missing transverse momentum in pp collisions at √s=13 TeV

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    Search results are presented for physics beyond the standard model in final states with two opposite-charge, same-flavor leptons, jets, and missing transverse momentum. The data sample corresponds to an integrated luminosity of 35.9 fb−1 of proton-proton collisions at s√=13 TeV collected with the CMS detector at the LHC in 2016. The analysis uses the invariant mass of the lepton pair, searching for a kinematic edge or a resonant-like excess compatible with the Z boson mass. The search for a kinematic edge targets production of particles sensitive to the strong force, while the resonance search targets both strongly and electroweakly produced new physics. The observed yields are consistent with the expectations from the standard model, and the results are interpreted in the context of simplified models of supersymmetry. In a gauge mediated supersymmetry breaking (GMSB) model of gluino pair production with decay chains including Z bosons, gluino masses up to 1500–1770 GeV are excluded at the 95% confidence level depending on the lightest neutralino mass. In a model of electroweak chargino-neutralino production, chargino masses as high as 610 GeV are excluded when the lightest neutralino is massless. In GMSB models of electroweak neutralino-neutralino production, neutralino masses up to 500-650 GeV are excluded depending on the decay mode assumed. Finally, in a model with bottom squark pair production and decay chains resulting in a kinematic edge in the dilepton invariant mass distribution, bottom squark masses up to 980–1200 GeV are excluded depending on the mass of the next-to-lightest neutralino
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