264 research outputs found
Short-term efficacy of physical interventions in osteoarthritic knee pain. A systematic review and meta-analysis of randomised placebo-controlled trials.
- Author
- A Andrianakos
- A Fargas-Babjak
- A Gur
- A Khadilkar
- A Molsberger
- A White
- AF Shaughnessy
- Anne E Ljunggren
- AR Jadad
- AS Quirk
- B Hegedus
- B Lewis
- B Nivbrant
- BM Berman
- BĂ„rd Bogen
- C Sangdee
- C Witt
- CJ Derry
- CR Smith
- D Carroll
- D Lewis
- DH Trock
- DH Trock
- DJ Hunter
- DT Felson
- E Naredo
- EM Roos
- ES Pessoa
- EW Ehrich
- F Angst
- F Song
- F Tubach
- GL Cheing
- H Jensen
- HH Dubben
- J Low
- J Stelian
- J Vas
- Jan M Bjordal
- JB Walker
- JH Kellgren
- JM Bjordal
- JM Bjordal
- JM Bjordal
- JM Bjordal
- JM Bjordal
- JM Bjordal
- JP Ioannidis
- K Grimmer
- K Ishimaru
- KA Sluka
- KD Brandt
- KG Baker
- KM Jordan
- KM Jordan
- L Brosseau
- L Chesterton
- M Egger
- M Osiri
- M Yurtkuran
- M Yurtkuran
- Mark I Johnson
- MI Johnson
- MJ Smith
- MJA Klaber
- MP Steultjens
- N Bellamy
- N Bellamy
- N Pipitone
- N Wiebe
- P Barlas
- P Nicolakis
- P Taylor
- P White
- PM Bulow
- PM Peloso
- PP Law
- R Defrin
- R Lubart
- Roberta Chow
- Rodrigo AB Lopes-Martins
- S Götte
- SM Cowan
- T Harlow
- VJ Robertson
- W Takeda
- World Association for Laser Therapy - WALT
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2007
- Field of study
BACKGROUND: Treatment efficacy of physical agents in osteoarthritis of the knee (OAK) pain has been largely unknown, and this systematic review was aimed at assessing their short-term efficacies for pain relief. METHODS: Systematic review with meta-analysis of efficacy within 1-4 weeks and at follow up at 1-12 weeks after the end of treatment. RESULTS: 36 randomised placebo-controlled trials (RCTs) were identified with 2434 patients where 1391 patients received active treatment. 33 trials satisfied three or more out of five methodological criteria (Jadad scale). The patient sample had a mean age of 65.1 years and mean baseline pain of 62.9 mm on a 100 mm visual analogue scale (VAS). Within 4 weeks of the commencement of treatment manual acupuncture, static magnets and ultrasound therapies did not offer statistically significant short-term pain relief over placebo. Pulsed electromagnetic fields offered a small reduction in pain of 6.9 mm [95% CI: 2.2 to 11.6] (n = 487). Transcutaneous electrical nerve stimulation (TENS, including interferential currents), electro-acupuncture (EA) and low level laser therapy (LLLT) offered clinically relevant pain relieving effects of 18.8 mm [95% CI: 9.6 to 28.1] (n = 414), 21.9 mm [95% CI: 17.3 to 26.5] (n = 73) and 17.7 mm [95% CI: 8.1 to 27.3] (n = 343) on VAS respectively versus placebo control. In a subgroup analysis of trials with assumed optimal doses, short-term efficacy increased to 22.2 mm [95% CI: 18.1 to 26.3] for TENS, and 24.2 mm [95% CI: 17.3 to 31.3] for LLLT on VAS. Follow-up data up to 12 weeks were sparse, but positive effects seemed to persist for at least 4 weeks after the course of LLLT, EA and TENS treatment was stopped. CONCLUSION: TENS, EA and LLLT administered with optimal doses in an intensive 2-4 week treatment regimen, seem to offer clinically relevant short-term pain relief for OAK
Search for pair-produced long-lived neutral particles decaying to jets in the ATLAS hadronic calorimeter in ppcollisions at âs=8TeV
- Author
- Aad G
- Abbott B
- Abdallah J
- Abdinov O
- Aben R
- Abi B
- Abolins M
- AbouZeid OS
- Abramowicz H
- Abreu H
- Abreu R
- Abulaiti Y
- Acharya BS
- Adamczyk L
- Adams DL
- Adelman J
- Adomeit S
- Adye T
- Agatonovic-Jovin T
- Aguilar-Saavedra JA
- Agustoni M
- Ahlen SP
- Ahmadov F
- Aielli G
- Akerstedt H
- Akesson TP
- Akimoto G
- Akimov AV
- Alberghi GL
- Albert J
- Albrand S
- Aleksa M
- Aleksandrov IN
- Alexa C
- Alexander G
- Alexandre G
- Alexopoulos T
- Alhroob M
- Alimonti G
- Alio L
- Alison J
- Allbrooke BMM
- Allison LJ
- Allport PP
- Aloisio A
- Alonso A
- Alonso F
- Alpigiani C
- Altheimer A
- Alviggi MG
- Amako K
- Amelung C
- Amidei D
- Amorim A
- Amoroso S
- Amram N
- Amundsen G
- Anastopoulos C
- Ancu LS
- Andari N
- Andeen T
- Anders CF
- Anders G
- Anderson KJ
- Andrade Filho LMD
- Andreazza A
- Andrei V
- Anduaga XS
- Angelidakis S
- Angelozzi I
- Anger P
- Angerami A
- Anghinolfi F
- Anisenkov AV
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- Antos J
- Anulli F
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- Apolle R
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- Argyropoulos S
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- Zutshi V
- Zwalinski L
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2014
- Field of study
The ATLAS detector at the Large Hadron Collider at CERN is used to search for the decay of a scalar boson to a pair of long-lived particles, neutral under the Standard Model gauge group, in 20.3fbâ1of data collected in protonâproton collisions at âs=8TeV. This search is sensitive to long-lived particles that decay to Standard Model particles producing jets at the outer edge of the ATLAS electromagnetic calorimeter or inside the hadronic calorimeter. No significant excess of events is observed. Limits are reported on the product of the scalar boson production cross section times branching ratio into long-lived neutral particles as a function of the proper lifetime of the particles. Limits are reported for boson masses from 100 GeVto 900 GeV, and a long-lived neutral particle mass from 10 GeVto 150 GeV
Search for new phenomena in final states with an energetic jet and large missing transverse momentum in pp collisions at â s = 8 TeV with the ATLAS detector
- Author
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- Abbott DC
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- Abhayasinghe DK
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- Zhemchugov A
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- Zivkovic L
- Zobernig G
- Zoccoli A
- Zoch K
- Zorbas TG
- Zou R
- Zu Theenhausen HM
- Zwalinski L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2015
- Field of study
Results of a search for new phenomena in final states with an energetic jet and large missing transverse momentum are reported. The search uses 20.3 fbâ1 of â s = 8 TeV data collected in 2012 with the ATLAS detector at the LHC. Events are required to have at least one jet with pT > 120 GeV and no leptons. Nine signal regions are considered with increasing missing transverse momentum requirements between Emiss T > 150 GeV and Emiss T > 700 GeV. Good agreement is observed between the number of events in data and Standard Model expectations. The results are translated into exclusion limits on models with either large extra spatial dimensions, pair production of weakly interacting dark matter candidates, or production of very light gravitinos in a gauge-mediated supersymmetric model. In addition, limits on the production of an invisibly decaying Higgs-like boson leading to similar topologies in the final state are presente
Identification of Pathogenicity-Related Genes in the Vascular Wilt Fungus Verticillium dahliae by Agrobacterium tumefaciens-Mediated T-DNA Insertional Mutagenesis
- Author
- A Carroll
- A Klimes
- A Tzima
- AW Peplow
- CB Michielse
- CJ Knight
- CL Gough
- D White
- DA Shah
- DP Roberts
- E Brunner
- ED Mullins
- EF Fradin
- G Lorenzo De
- GE Vallad
- GF Pegg
- H Ochman
- HS Rho
- IF Parra
- J Choi
- J Jeon
- JY Wang
- K Kapoor
- K Maruthachalam
- K Maruthachalam
- K. Maruthachalam
- K. V. Subbarao
- KF Dobinson
- L Harispe
- L Schaible
- M Novo
- MJA Groot de
- MR Thon
- P Bundock
- P Rauyaree
- P Talhinhas
- PJJ Hooykaas
- R Hayes
- R Prasad
- R. J. Hayes
- RF Selden
- RG Bhat
- RS Goswami
- S. J. Klosterman
- S. Kang
- SF Altschul
- SJ Grimme
- SJ Klosterman
- SJ Klosterman
- ST Koike
- TH Al-Samarrai
- V Meyer
- V Valaskova
- W Souza de
- X Chen
- Y Meng
- Y Yamamura
- Publication venue
- Humana Press Inc
- Publication date
- 01/01/2011
- Field of study
Verticillium dahliae is the causal agent of vascular wilt in many economically important crops worldwide. Identification of genes that control pathogenicity or virulence may suggest targets for alternative control methods for this fungus. In this study, Agrobacteriumtumefaciens-mediated transformation (ATMT) was applied for insertional mutagenesis of V. dahliae conidia. Southern blot analysis indicated that T-DNAs were inserted randomly into the V. dahliae genome and that 69% of the transformants were the result of single copy T-DNA insertion. DNA sequences flanking T-DNA insertion were isolated through inverse PCR (iPCR), and these sequences were aligned to the genome sequence to identify the genomic position of insertion. V. dahliae mutants of particular interest selected based on culture phenotypes included those that had lost the ability to form microsclerotia and subsequently used for virulence assay. Based on the virulence assay of 181 transformants, we identified several mutant strains of V. dahliae that did not cause symptoms on lettuce plants. Among these mutants, T-DNA was inserted in genes encoding an endoglucanase 1 (VdEg-1), a hydroxyl-methyl glutaryl-CoA synthase (VdHMGS), a major facilitator superfamily 1 (VdMFS1), and a glycosylphosphatidylinositol (GPI) mannosyltransferase 3 (VdGPIM3). These results suggest that ATMT can effectively be used to identify genes associated with pathogenicity and other functions in V. dahliae
Withholding or withdrawal of treatment under French rules: a study performed in 43 intensive care units
- Author
- A Esteban
- A Giannini
- A KĂŒbler
- A Yaguchi
- AE Barnato
- AR Parry-Jones
- CL Sprung
- CL Sprung
- CL Sprung
- CL Sprung
- D Cook
- D Wilkinson
- DB White
- DJ Cook
- DJC Wilkinson
- DN Forte
- DW Frost
- E Azoulay
- E Ferrand
- F Paruk
- G Bertolini
- H Hoel
- H-H BĂŒlow
- I Ouanes
- J Phua
- J-L Vincent
- JL Vincent
- JP Quenot
- JR Curtis
- JR Curtis
- JR Gall Le
- M Geurts
- MA Verkade
- ME Charlson
- ME Wilson
- MJ Silveira
- MJA Kamps
- N CĂŽte
- N Zamperetti
- NA Christakis
- O Lesieur
- R Robert
- RD Truog
- Société de Réanimation de Langue Française
- TE Quill
- V Metaxa
- WA Knaus
- WR McCabe
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Insulin receptor has tyrosine kinase activity toward Shc in rat liver
- Author
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
Measurement of the transverse polarization of Î and ÎÂŻ hyperons produced in proton-proton collisions at âs=7ââTeV using the ATLAS detector
- Author
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- Abbott B
- Abdallah J
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- Abramowicz H
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- Acharya BS
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- Alberghi GL
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- Allbrooke BMM
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- Zaidan R
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- Zemla A
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- Zhemchugov A
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- Zobernig G
- Zoccoli A
- Zurzolo G
- Zwalinski L
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 01/12/2014
- Field of study
The transverse polarization of Î and ÎÂŻ hyperons produced in proton-proton collisions at a center-of-mass energy of 7 TeV is measured. The analysis uses 760ââÎŒbâ1 of minimum bias data collected by the ATLAS detector at the LHC in the year 2010. The measured transverse polarization averaged over Feynman xF from 5Ă10â5 to 0.01 and transverse momentum pT from 0.8 to 15 GeV is â0.010±0.005(stat)±0.004(syst) for Î and 0.002±0.006(stat)±0.004(syst) for ÎÂŻ. It is also measured as a function of xF and pT, but no significant dependence on these variables is observed. Prior to this measurement, the polarization was measured at fixed-target experiments with center-of-mass energies up to about 40 GeV. The ATLAS results are compatible with the extrapolation of a fit from previous measurements to the xF range covered by this measurement
Measurements of integrated and differential cross sections for isolated photon pair production in pp collisions at âs=8 TeV with the ATLAS detector
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- Yildirim E
- Yildiz HD
- Yorita K
- Yoshihara K
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- Yusuff I
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- Zaidan R
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- Zakharchuk N
- Zalieckas J
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- Zambito S
- Zanzi D
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- Zemla A
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- Zeng Q
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- Zhao Z
- Zhemchugov A
- Zhou B
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- Zhou M
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- Zhu CG
- Zhu H
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- Zhu Y
- Zhuang X
- Zhukov K
- Zibell A
- Zieminska D
- Zimine NI
- Zimmermann C
- Zimmermann S
- Zinonos Z
- Zinser M
- Ziolkowski M
- Zivkovic L
- Zobernig G
- Zoccoli A
- Zou R
- Zwalinski L
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 01/01/2017
- Field of study
A measurement of the production cross section for two isolated photons in proton-proton collisions at a center-of-mass energy of âs=8 TeV is presented. The results are based on an integrated luminosity of 20.2 fbâ1 recorded by the ATLAS detector at the Large Hadron Collider. The measurement considers photons with pseudorapidities satisfying |ηγ|40GeV and EÎłT,2>30 GeV for the two leading photons ordered in transverse energy produced in the interaction. The background due to hadronic jets and electrons is subtracted using data-driven techniques. The fiducial cross sections are corrected for detector effects and measured differentially as a function of six kinematic observables. The measured cross section integrated within the fiducial volume is 16.8 ± 0.8â pb . The data are compared to fixed-order QCD calculations at next-to-leading-order and next-to-next-to-leading-order accuracy as well as next-to-leading-order computations including resummation of initial-state gluon radiation at next-to-next-to-leading logarithm or matched to a parton shower, with relative uncertainties varying from 5% to 20%
Search for the b(b)over-bar decay of the Standard Model Higgs boson in associated (W/Z)H production with the ATLAS detector
- Author
- Aad G
- Abbott B
- Abdallah J
- Abdinov O
- Aben R
- Abi B
- Abolins M
- AbouZeid OS
- Abramowicz H
- Abreu H
- Abreu R
- Abulaiti Y
- Acharya BS
- Adam ER
- Adamczyk L
- Adams DL
- Adelman J
- Adomeit S
- Adye T
- Agatonovic-Jovin T
- Aguilar-Saavedra JA
- Agustoni M
- Ahlen SP
- Ahmadov F
- Aielli G
- Akerstedt H
- Akesson TPA
- Akimoto G
- Akimov AV
- Alberghi GL
- Albert J
- Albrand S
- Aleksa M
- Aleksandrov IN
- Alexa C
- Alexander G
- Alexandre G
- Alexopoulos T
- Alhroob M
- Alimonti G
- Alio L
- Alison J
- Allbrooke BMM
- Allison LJ
- Allport PP
- Aloisio A
- Alonso A
- Alonso F
- Alpigiani C
- Altheimer A
- Alviggi MG
- Amako K
- Amelung C
- Amidei D
- Amorim A
- Amoroso S
- Amram N
- Amundsen G
- Anastopoulos C
- Ancu LS
- Andari N
- Andeen T
- Anders G
- Andersb CF
- Anderson KJ
- Andreazza A
- Andrei V
- Anduaga XS
- Angelidakis S
- Angelozzi I
- Anger P
- Angerami A
- Anghinolfi F
- Anh TV
- Anisenkov AV
- Anjos N
- Annovi A
- Antonaki A
- Antonelli M
- Antonov A
- Antos J
- Anulli F
- Aoki M
- Apolle R
- Arabidze G
- Aracena I
- Arai Y
- Aranda CP
- Araque JP
- Arce ATH
- Arduh FA
- Arguin J-F
- Argyropoulos S
- Arik M
- Armadans RC
- Armbruster AJ
- Arnaez O
- Arnal V
- Arnold H
- Arratia M
- Arslan O
- Artamonov A
- Artoni G
- Asai S
- Asbah N
- Ashkenazi A
- Asman B
- Asquith L
- Assamagan K
- Astalos R
- Atkinson M
- Atlay NB
- Auerbach B
- Augsten K
- Aurousseau M
- Avolio G
- Axen B
- Azuelos G
- Azuma Y
- Baak MA
- Baas AE
- Bacci C
- Bachacou H
- Bachas K
- Backes M
- Backhaus M
- Badescu E
- Bagiacchi P
- Bagnaia P
- Bai Y
- Bain T
- Baines JT
- Baker OK
- Balek P
- Balli F
- Banas E
- Banerjee S
- Bannoura AAE
- Bansal V
- Bansil HS
- Barajas CAC
- Barak L
- Baranov SP
- Barberio EL
- Barberis D
- Barbero M
- Barillari T
- Barisonzi M
- Barklow T
- Barlow N
- Barnes SL
- Barnett BM
- Barnett RM
- Barnovska Z
- Baroncelli A
- Barone G
- Barr AJ
- Barreiro F
- Barrera CO
- Bartoldus R
- Barton AE
- Bartos P
- Bartsch V
- Bassalat A
- Basye A
- Bates RL
- Batley JR
- Battaglia M
- Battistin M
- Bauer F
- Bawa HS
- Beattie MD
- Beau T
- Beauchemin PH
- Beccherle R
- Bechtle P
- Beck HP
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- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2015
- Field of study
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Measurement of W+Wâ production in association with one jet in protonâproton collisions at sqrt(s) = 8TeV with the ATLAS detector
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- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2016
- Field of study
The production of W boson pairs in association with one jet in pp collisions at View the MathML sources=8 TeV is studied using data corresponding to an integrated luminosity of 20.3 fbâ1 collected by the ATLAS detector during 2012 at the CERN Large Hadron Collider. The cross section is measured in a fiducial phase-space region defined by the presence of exactly one electron and one muon, missing transverse momentum and exactly one jet with a transverse momentum above 25 GeV and a pseudorapidity of |η|<4.5|η|<4.5. The leptons are required to have opposite electric charge and to pass transverse momentum and pseudorapidity requirements. The fiducial cross section is found to be View the MathML sourceÏWWfid,1-jet=136±6(stat)±14(syst)±3(lumi) fb. In combination with a previous measurement restricted to leptonic final states with no associated jets, the fiducial cross section of WW production with zero or one jet is measured to be View the MathML sourceÏWWfid,â€1-jet=511±9(stat)±26(syst)±10(lumi) fb. The ratio of fiducial cross sections in final states with one and zero jets is determined to be 0.36±0.050.36±0.05. Finally, a total cross section extrapolated from the fiducial measurement of WW production with zero or one associated jet is reported. The measurements are compared to theoretical predictions and found in good agreement
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