Navegar é impreciso: um estudo comparado das críticas de Antonio Candido e Eduardo Lourenço

Doutoramento em Estudos CulturaisEsta tese move-se através de leituras dialogantes do crítico literário, mas também sociólogo brasileiro, Antonio Candido e do crítico literário, também filósofo cultural português, Eduardo Lourenço. Pretende-se um estudo comparado, em especial, de seus ensaísmos de crítica literária, e busca compreender o que separa a intimidade hermenêutica dos dois autores, ambos adeptos de uma transposição de fronteiras do conhecimento. Parte por contrapor as ideias de contradição e heterodoxia, perscrutando, em suas obras, o peso que elas tiveram na construção de uma metodologia crítica, ainda que bastante intuitiva nos dois casos, e como sustentam suas distintas análises literárias: estético-social, para Candido, e estético-ontológica, para Lourenço. Mais especificamente, esta tese empenha-se em refletir sobre seus pensamentos a respeito da crítica literária, suas compreensões no que tange às identidades culturais nacionais, e mesmo transnacionais, sobre o papel que podemos conceder à literatura no mundo contemporâneo enquanto modo de aproximação ao complexo sentido da liberdade, e como encontram no ensaio, cada qual ao seu modo, uma forma não-forma donde emergir suas críticas literárias e pensamentos, que, embora distantes no que há de mais essencial, coincidem na total entrega à primazia do texto literário.This thesis moves within the dialogue readings of the literary critic, but also Brazilian sociologist, Antonio Candido and the literary critic, as well Portuguese cultural philosopher, Eduardo Lourenço. We intent with this comparative study, and especially, of their essays of literary critic, and search to understand what separate the hermeneutics intimacy of these two authors, both supporters of a transposition of the frontiers of knowledge. We start by opposing the ideas of contradiction and heterodoxy, peering, in their works, the weight that they had in the construction of a critical methodology, although very intuitive in both cases, and how they maintain their distinct literary analysis: aesthetic-social for Candido, and aesthetic-ontological, to Lourenço. More specifically, this thesis intents to reflect their thoughts on literary criticism, their comprehensions of the national cultural identities, and even transnational, of the role that we can concede to literature in the contemporary world as a way of approaching to the complex sense of freedom, and how they find within the essay, each in his own way, a form of non form from where to emerge of their literary criticism and thoughts, which, although distant in what is of most essential, coincide on total commitment to the primacy of the literary text

Environmental drivers of water use for Caatinga woody plant species: combining remote sensing phenology and sap flow measurements

Abstract: We investigated the water use of Caatinga vegetation, the largest seasonally dry forest in South America. We identified and analysed the environmental drivers of phenology in woody species and their relationship with transpiration. To monitor the phenological evolution we used remote sensing indices at different spatial and temporal scales: normalized difference vegetation index (NDVI), soil adjusted vegetation index (SAVI), and green chromatic coordinate (GCC). To represent the phenology we used the GCC extracted from in-situ automated digital camera images; indices calculated based on sensors included NDVI, SAVI and GCC from Sentinel-2A and B satellites images, and NDVI products MYD13Q1 and MOD13Q1 from moderate-resolution imaging spectroradiometer (MODIS). Environmental drivers included continuously monitored rainfall, air temperature, soil moisture, net radiation, and vapour pressure deficit. To monitor soil water status and vegetation water use we installed soil moisture sensors along three soil profiles and sap flow sensors for five plant species. Our study demonstrated that the near-surface GCC data played an important role in allowing individual monitoring of species whereas the species’ sap flow data correlated better with NDVI, SAVI and GCC than with species’ near-surface GCC. The wood density appeared to affect the transpiration cessation times in the dry season given species with the lowest wood density reach negligible values of transpiration earlier in the season than those with high woody density. Our results show that soil water availability is the main limiting factor for transpiration during more than 80 % of the year, and that both the phenological response and water use are directly related to water availability when relative saturation of the soil profile falls below 0.25

Práxis educativa inovadora na anatomia e na cirurgia: relato de experiência

Introdução: O fomento de uma práxis com um olhar interdisciplinar aprimora a aprendizagem e precisa ser encorajada. No curso de Medicina de nossa instituição, esta foi uma realidade para os componentes curriculares de Técnicas Cirúrgicas e Anatomia Humana. O objetivo desta metodologia inovadora foi, primordialmente, a necessidade de utilização racional dos animais de experimentação promovendo o acesso à dissecação para a aprendizagem das estruturas anatômicas e suas sintopias, bem como o manuseio de instrumentos cirúrgicos, indispensáveis para a formação médica integral. Objetivos: Relatar a experiência de alunos de Medicina com a técnica de dissecação em monoblocos suínos, bem como explorar seus pontos positivos e benefícios na aprendizagem e futura atuação médica. Relato de experiência: Esta realidade é possível por meio da coleta dos órgãos de suínos que são utilizados para pequenos procedimentos durante as aulas de Técnicas Cirúrgicas e que posteriormente são utilizados nos cursos da Anatomia. O fundamento teórico da coleta dos órgãos seguiu técnicas de necropsia, visando manter os órgãos em um monobloco desde a boca até o reto para posterior estudo por similaridade durante os cursos de dissecação. Conclusão: Esses métodos de aprendizagem anatômica e cirúrgica foram de extrema importância para a construção de profissionais capacitados, éticos, confiantes e com boas habilidades técnicas

Post-intervention Status in Patients With Refractory Myasthenia Gravis Treated With Eculizumab During REGAIN and Its Open-Label Extension

OBJECTIVE: To evaluate whether eculizumab helps patients with anti-acetylcholine receptor-positive (AChR+) refractory generalized myasthenia gravis (gMG) achieve the Myasthenia Gravis Foundation of America (MGFA) post-intervention status of minimal manifestations (MM), we assessed patients' status throughout REGAIN (Safety and Efficacy of Eculizumab in AChR+ Refractory Generalized Myasthenia Gravis) and its open-label extension. METHODS: Patients who completed the REGAIN randomized controlled trial and continued into the open-label extension were included in this tertiary endpoint analysis. Patients were assessed for the MGFA post-intervention status of improved, unchanged, worse, MM, and pharmacologic remission at defined time points during REGAIN and through week 130 of the open-label study. RESULTS: A total of 117 patients completed REGAIN and continued into the open-label study (eculizumab/eculizumab: 56; placebo/eculizumab: 61). At week 26 of REGAIN, more eculizumab-treated patients than placebo-treated patients achieved a status of improved (60.7% vs 41.7%) or MM (25.0% vs 13.3%; common OR: 2.3; 95% CI: 1.1-4.5). After 130 weeks of eculizumab treatment, 88.0% of patients achieved improved status and 57.3% of patients achieved MM status. The safety profile of eculizumab was consistent with its known profile and no new safety signals were detected. CONCLUSION: Eculizumab led to rapid and sustained achievement of MM in patients with AChR+ refractory gMG. These findings support the use of eculizumab in this previously difficult-to-treat patient population. CLINICALTRIALSGOV IDENTIFIER: REGAIN, NCT01997229; REGAIN open-label extension, NCT02301624. CLASSIFICATION OF EVIDENCE: This study provides Class II evidence that, after 26 weeks of eculizumab treatment, 25.0% of adults with AChR+ refractory gMG achieved MM, compared with 13.3% who received placebo

Minimal Symptom Expression' in Patients With Acetylcholine Receptor Antibody-Positive Refractory Generalized Myasthenia Gravis Treated With Eculizumab

The efficacy and tolerability of eculizumab were assessed in REGAIN, a 26-week, phase 3, randomized, double-blind, placebo-controlled study in anti-acetylcholine receptor antibody-positive (AChR+) refractory generalized myasthenia gravis (gMG), and its open-label extension

Optimasi Portofolio Resiko Menggunakan Model Markowitz MVO Dikaitkan dengan Keterbatasan Manusia dalam Memprediksi Masa Depan dalam Perspektif Al-Qur`an

Risk portfolio on modern finance has become increasingly technical, requiring the use of sophisticated mathematical tools in both research and practice. Since companies cannot insure themselves completely against risk, as human incompetence in predicting the future precisely that written in Al-Quran surah Luqman verse 34, they have to manage it to yield an optimal portfolio. The objective here is to minimize the variance among all portfolios, or alternatively, to maximize expected return among all portfolios that has at least a certain expected return. Furthermore, this study focuses on optimizing risk portfolio so called Markowitz MVO (Mean-Variance Optimization). Some theoretical frameworks for analysis are arithmetic mean, geometric mean, variance, covariance, linear programming, and quadratic programming. Moreover, finding a minimum variance portfolio produces a convex quadratic programming, that is minimizing the objective function ðð¥with constraintsð ð 𥠥 ðandð´ð¥ = ð. The outcome of this research is the solution of optimal risk portofolio in some investments that could be finished smoothly using MATLAB R2007b software together with its graphic analysis

Differential cross section measurements for the production of a W boson in association with jets in proton–proton collisions at √s = 7 TeV

Measurements are reported of differential cross sections for the production of a W boson, which decays into a muon and a neutrino, in association with jets, as a function of several variables, including the transverse momenta (pT) and pseudorapidities of the four leading jets, the scalar sum of jet transverse momenta (HT), and the difference in azimuthal angle between the directions of each jet and the muon. The data sample of pp collisions at a centre-of-mass energy of 7 TeV was collected with the CMS detector at the LHC and corresponds to an integrated luminosity of 5.0 fb[superscript −1]. The measured cross sections are compared to predictions from Monte Carlo generators, MadGraph + pythia and sherpa, and to next-to-leading-order calculations from BlackHat + sherpa. The differential cross sections are found to be in agreement with the predictions, apart from the pT distributions of the leading jets at high pT values, the distributions of the HT at high-HT and low jet multiplicity, and the distribution of the difference in azimuthal angle between the leading jet and the muon at low values.United States. Dept. of EnergyNational Science Foundation (U.S.)Alfred P. Sloan Foundatio

Search for stop and higgsino production using diphoton Higgs boson decays

Results are presented of a search for a "natural" supersymmetry scenario with gauge mediated symmetry breaking. It is assumed that only the supersymmetric partners of the top-quark (stop) and the Higgs boson (higgsino) are accessible. Events are examined in which there are two photons forming a Higgs boson candidate, and at least two b-quark jets. In 19.7 inverse femtobarns of proton-proton collision data at sqrt(s) = 8 TeV, recorded in the CMS experiment, no evidence of a signal is found and lower limits at the 95% confidence level are set, excluding the stop mass below 360 to 410 GeV, depending on the higgsino mass

Search for heavy resonances decaying to two Higgs bosons in final states containing four b quarks

A search is presented for narrow heavy resonances X decaying into pairs of Higgs bosons (H) in proton-proton collisions collected by the CMS experiment at the LHC at root s = 8 TeV. The data correspond to an integrated luminosity of 19.7 fb(-1). The search considers HH resonances with masses between 1 and 3 TeV, having final states of two b quark pairs. Each Higgs boson is produced with large momentum, and the hadronization products of the pair of b quarks can usually be reconstructed as single large jets. The background from multijet and t (t) over bar events is significantly reduced by applying requirements related to the flavor of the jet, its mass, and its substructure. The signal would be identified as a peak on top of the dijet invariant mass spectrum of the remaining background events. No evidence is observed for such a signal. Upper limits obtained at 95 confidence level for the product of the production cross section and branching fraction sigma(gg -> X) B(X -> HH -> b (b) over barb (b) over bar) range from 10 to 1.5 fb for the mass of X from 1.15 to 2.0 TeV, significantly extending previous searches. For a warped extra dimension theory with amass scale Lambda(R) = 1 TeV, the data exclude radion scalar masses between 1.15 and 1.55 TeV

Search for supersymmetry in events with one lepton and multiple jets in proton-proton collisions at root s=13 TeV

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