28 research outputs found
Young Children’s Use of Mobile Technology: Impacts on Self-Regulation and Aggression
- Author
- Publication venue
- 'University of Windsor Leddy Library'
- Publication date
- 27/09/2018
- Field of study
The present study tested the displacement hypothesis, which proposed that mobile technology use disrupts important daily activities and social interactions that are important for the development of young children’s self-regulation skills (Gentile et al., 2012). As a result of this displacement, children are more likely to become dysregulated and aggressive. Participants were 174 caregivers (n = 157 mothers) who reported on their children aged 2 to 5 years old (n = 100 male). All participants completed self-report questionnaires assessing their own technology use, interference in the parent-child relationship due to mobile technology, and the use of mobile technology as a parenting tool. Caregivers also reported on their children’s use of mobile technology, participation in the environment, self-regulation, aggressive behaviour, and temperament. A subset of 15 caregivers (n = 14 mothers) also answered open-ended interview questions about their attitudes, perceptions, and experiences regarding mobile technology use in the family. The analyses revealed that mobile technology use by both caregivers and children negatively impacted young children’s self-regulation and aggressive behaviour. Greater use of mobile technology was found to displace daily activities and social interactions, leading to greater dysregulation and aggression. Results also demonstrated that greater use of mobile technology as parenting tools mediated the relation between greater mobile technology use and children’s aggressive behaviour. A thematic analysis of caregivers’ interviews revealed that caregivers have many strategies to monitor their children’s media activity, concerns about the negative impacts of mobile technology, and tensions about using these devices in the family. The novelty of these findings address gaps in the literature by identifying various ways in which mobile technology can interfere with young children’s daily lives in a way that is detrimental for the development of their self-regulation and aggressive behaviour
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- Kettleborough Ross
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- Madabhushi Ramki
- Madu Renita C.
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- Nwokenkwo Stanley
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- Omotosho Bamidele
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- Perez Lesette M.
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- Schatzkamer Kyriena L.
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- Subramanian Sandhya
- Sudbrak Ralf
- Sugnet Charles W.
- Sulston John
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- Sun Hui
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- Sun Min
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- Sun Yongqiao
- Sun Yu
- Sun Yue
- Sutherland Grant R.
- Sutherland Robert D.
- Sutton Angelica E.
- Svatek Amanda F.
- Svetz Jessica
- Svetz Leah Anne
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- Tan Xinyu
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- Tatsuyama Miho
- Tatum Owatha I.
- Taudien Stefan
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- Tian Chaoguang
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- Tong Jingli
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- Tsukamoto Yumi
- Tsuruoka Hiromi
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- Zhang Xiuqing
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- Zhang Yilin
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- Zhang Yuzhi
- Zhang Zhengdong
- Zhao Hongmei
- Zhao Lijian
- Zhao Shenru
- Zhao Zhijing
- Zhen Zhicheng
- Zheng Haibo
- Zhong Ming
- Zhou Carol
- Zhou Haixia
- Zhou Jianling
- Zhou Nannan
- Zhou Xinfeng
- Zhou Yan
- Zhou Yang
- Zhou Yi
- Zhu Bingying
- Zhu Bofeng
- Zhu Fenghua
- Zhu Genfeng
- Zhu Genfeng
- Zhu Miao
- Zhu Ning
- Zhu Yongge
- Zhu Zhen
- Zhuang Shitao
- Zierten Deborah
- Zimmer Andrew
- Zody Michael C.
- Zollo Massimo
- Zorrilla Sara E.
- Zuo Lin
- Publication venue
- LSU Digital Commons
- Publication date
- 21/10/2004
- Field of study
The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead
Impact of opioid-free analgesia on pain severity and patient satisfaction after discharge from surgery: multispecialty, prospective cohort study in 25 countries
- Author
- Aamir Faiqa Binte
- Aamir Syed Roohan
- Ababneh Adnan
- Abbal Muhammad Anas
- Abbas Ahmed M
- Abbas Mostafa
- Abd-Albain Montasir A
- Abdalei Abdulwahab
- Abdalla Ahmed
- Abdalla Ahmed Yassir
- Abdalla Mohamed Galal Ali
- Abdalla Zainab
- Abdallah Mohamed M
- Abdalmahmoud Noon Ezzeldien
- Abdalsadeg Rowa
- Abdelaal Ahmed M
- Abdelbagi Alnazeer Y
- Abdelbaky Mostafa
- Abdelbaset Doaa
- AbdElbaset Esraa
- Abdelbast Menhag
- Abdelfatah Mohammed Abdelnasser
- Abdelgawad Samia
- Abdelhamid Mohamed M
- Abdeljaber Mahmoud
- Abdelkhalig Mubarak
- Abdelmaksoud Mohamed
- Abdelmeguid Rana
- Abdelmelek Dhia Errahmane
- Abdelnaeam Samah
- Abdelnasser Mohammad K
- Abdelrahim Najwa
- Abdelrahman Amira
- Abdelrahman Ayman
- Abdelsalam Hebatalla
- Abdelsamed Enas Abdelbaset
- Abdelwahab Khaled
- Abdoun Meriem
- Abdulali Fatima
- Abdulaziz Mohamed
- Abdulla Dheba Almukhtar
- Abdullah Bahiyah
- Abdullah Bahiyah
- Abdullah Walaa
- Abdullahi Habiba Ibrahim
- Abdulrahman Ahmed
- Abdulrasheed Lubabatu
- Abdulwahed Eman
- Abdulwahed Eman
- Abeysirigunawardana Dewmi
- Abidin Muhammad Fihmi Zainal
- Abiola Olukayode
- Abiyere Henry
- Abodina Ahmed Mohammed
- Aboelela Reham
- AboElfarh Hadeer Elsaeed
- Aboudlal Husein
- AbouHiekal Osama
- Aboulfotouh Ahmed
- Abozid Anwaar
- Abubaker Noora
- Abubaker Noora
- Abufanas Asma
- Abughanima Mahmoud
- Abuhashem Shehab
- Abulafia Daniel
- Abushaala Fatima
- Abushanab Khaled
- AbuShawareb Issa
- Abuuqteish Hamza
- Abuzaho Amany
- Achem Arome
- Adam Eithar
- Adam Mohammed
- Adam Mohammed A
- Addalla Mohamed
- Addley Jordan
- Adeleye Gbadebo
- Adeniyi Adebayo
- Adewole Nathaniel
- Adeyemo Olabisi
- Adeyeye Ademola
- Adeyeye Ademola
- Adly Michael
- Adnan Siti Nasyirah Nisya
- Ads Adel Mohamed
- Ads Alaa Mohamed
- Adze Joel Amwe
- Afeikhena Ehis
- Agida Teddy
- Agilla Hamza
- Agnew Emilie
- Agu Joy Onyekachi
- Ahmad Zatul Akmar
- Ahmed Abdalla
- Ahmed Ahmed
- Ahmed Ahmed
- Ahmed Alaaaldeen
- Ahmed Entisar
- Ahmed Habeeba
- Ahmed Hatem
- Ahmed Reem
- Ahmed Rehab
- Ahmed Rihab
- Ahmed Rogia Ahmed Abdalla
- Ahmed Ruaa
- Ahmed Sharwany
- Ahmed Uzair
- Ahmed Wahiba
- Ahmeed Sultan
- Airede Lydia Regina
- Aitchison Lori
- Ajredini Mirac
- Ajulo Adeshina A
- Akaba Godwin
- Akasha Mazin
- Akbar Maha Ghulam
- Akbuz Seyma Orcan
- Akdere Hakan
- Akın Bilge
- Akkaya Ege Nur
- Akpamgbo Chukwunonso Nnamdi
- Akwaisah Ayoub
- Al Hammoud Amr
- Al Rawashdeh Toka
- Al-Baw Mahmoud
- Al-Dahdouh Mosheer
- Al-Haek Safa’
- Al-Hazaimeh Mo'ath
- Al-issawi Dima
- Al-Issawi Subhi
- Al-jammal Maryam
- Al-Juaifari Maytham A
- Al-Mwajeh Tesneem
- Al-Omary Sohaib
- Al-Quossi Mohammed
- Al-Shambaty Yasir Babkir Ali
- Al-Shami Qotadah
- Al-Smirat Heba
- Al-Tahayneh Sief-Addeen
- Al-Touny Aiman
- Al-Touny Shimaa
- Al-zawaydeh Alia
- Alaa Ali
- Alabed Ebtihal
- Alagelli Fatma
- Alagoz Ahmet Can
- Alameen Hind
- Alameen Maram
- Alamlih Laith
- Alaqoubi Retaj
- Alarabi Rehab
- Alariby Fatima
- Alatefi Dawood
- Alathameen Nassar
- Albakosh Bashir Abobaker
- Albanopoulos Konstantinos
- Albarhomy Osama
- Albarki Aisha
- Albashaireh Alaa
- Albatni Safa Sasi
- Albayadi Eslam
- Alboon Mosab
- Alboridy Muneera
- Alboueishi Asraa Ali
- Aldeges Marwan
- Aldreawi Mohammed
- Alflite Asil Omar Saleh
- Alfrijat Tamam
- Alfrjani Tariq
- Algabbasi Salima
- Algatanesh Nassib
- Alhadad Qamrah
- Alhaddad Hoda Salem
- Alhaleem Ayah
- Alhaleeq Saif
- Alharam Abtisam
- Alhashimi Abdulhadi Mohammed Alhadi
- Alhassan Monzer
- Alhudhairy Sara
- Ali Ahmed
- Ali Aml
- Ali Doua
- Ali Eithar M
- Ali Iqra Fatima Munawar
- Ali Maab
- Ali Manal
- Ali Muhammad
- Ali Radwa
- Ali Rawan Alsheikh
- Ali Rzan Ali Hamedelneel
- Ali Shehroz
- Aliosin Oleg
- Aljamal Mohammad
- Aljamal Sarah
- Alkaraja Layth
- Alkaseek Akram
- Alkazali Mustafa
- Alkchr Hayat Ben Hasan Mohamed A A
- Alkhatib Abed Alazeez
- Allam Shereen
- Almahroush Marin
- Almakki Doha Mohammed Ahmed
- Alnajjar Lara
- Alnajjar Majjd
- Alnatsheh Wesam
- Alnour Ammar
- Alomar Rabiaa
- Alomari Yazan
- Alqaarh Aya
- Alragig Zahra
- Alrifae Ghaliya Mohamed H
- Alrosan Risan
- Alsagoff Sharifah Nor Amirah Syed Abdul Latiff
- Alsaid Hamza
- Alsaify Esmat
- Alsaih Sawsan
- Alsari Najah
- Alshareea Entisar
- Alshawadfy Abdelrhman
- Alshawesh Aisha
- Alsheik Ahmad
- Alsori Mohamed
- Alsoudani Ali
- Altabbaa Hashem
- Altahir Mohamed
- Altair Mawadda
- Altaweel Ahmad
- Altughar Bushra
- Alvarez Matias
- Alvarez-Lozada Luis Adrian
- Alvarez-Lozada Luis Adrian
- Alwahaib Anas
- Alwash Mohammed
- Alzarga Ali
- Alzarouq Ebtisam
- Alzarroug Amal
- Alzghoul Bader
- Alzyoud Osama
- Amarasekara Mishka
- Amary Marwa
- Ametov Amet
- Amin Mostafa K
- Aminu Bashiru
- Aminu Muhammad Baffah
- Ammar Ahmed Siddique
- Amro Dana
- Ananthapadmanabhan Shravankrishna
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- Vance Lucille
- Vanguardia Kristina
- Vanguardia Maria Kristina
- Vanzuylekom Katie
- Varesano Marco
- Varghese Chris
- Varghese Chris
- Velenciuc Natalia
- Vermeulen Wikus
- Vidanagama Sasini
- Vimalan Vineeth
- Virani Sehar Salim
- Vollenhoven Beverley
- Vong Crystal
- Vrakopoulou Gavriella Zoi
- Vu Jennifer
- Vu Jennifer
- Waaka Nicholas
- Wadhwa Sanya
- Wagaarachchi Prabhath
- Waheed Ayesha Akbar
- Waldin Lucy
- Walsh Eamon
- Walters Chris
- Wang Bill
- Wang Christine
- Wang Erica
- Wang Grace
- Wang Katie
- Wang Nicole Qiwen
- Wang Pengnan
- Wang Qiwen
- Wang Shelley
- Wang Yantong
- Wang Zixuan
- Waqar Usama
- Waraich Abdullah
- Ward Jack
- Wardeh Salah Abu
- Wasim Tayyiba
- Watson David
- Watson David
- Wedatalla Mansour
- Weeda Lewis
- Wells Cameron
- Wells Cameron
- Wells Cameron
- Wells Oliver
- Werenski Hope
- Wijayaratne Rivindu
- Wijetunga Asanka
- Williams Brittany
- Williams Peter
- Wilson Thomas
- Windsor John
- Windsor John
- Winthrop Lily
- Withanage Indrajith
- Wong James
- Wong Jason
- Wong Kenneth
- Wong King Ho
- Wong Patrick
- Wong Samantha
- Woodbridge Christian
- Wright Deborah
- Wright Deborah
- Wright Deborah
- Wu Alan
- Wu Alan
- Wu Chun-Yen
- Wu Hongyi
- Wycliff Daniel
- Xiao Haotian
- Xie Maria
- Xu Cindy
- Xu William
- Xu William
- Xu William
- Yaghmour Jamal
- Yahya Bilal Shuaibu
- Yahya Rawad
- Yang Wah
- Yao Michelle
- Yao Sunny
- Yao Sunny
- Yasar Meltem
- Yasir Ruaa
- Yassin Mohamed
- Yavuz Dogancan
- Yavuz Ikranur
- Yaytokgil Muhammet
- Yazgan Yasemin
- Yee Su-Ann
- Yeung Justin
- Yeung Kar Long
- Yew Anthea
- Yi Kevin
- Yiannakopoulos Christos
- Yildirim Yasemin
- Yildiz Ahmet
- Yıldız Berkay
- Yilmaz Hakan
- Yin Chonghao
- Ying Geoffrey
- Yodkitydomying Chatnapa
- Yong Nathania
- Yoon Si Woo
- You Ha Seong
- Young Simon
- Young Stevie
- Younus Khadijah
- Yousif Fatima Imad
- Yousri Mohamed
- Youssef Ahmed A
- Youssef Arkan
- Yu Hoi Hang
- Yu Victor
- Yuan Grace
- Yue Bosco
- Yue Tiffany
- Yunos Mohamed Haseef Mohamed
- Yusuf Stephen
- Yuzgec Ayse Nilufer
- Zachomitros Fotios
- Zaed Moahmed
- Zafar Fatima
- Zaghloul Ahmed
- Zaheer Adil
- Zaidi Faseeh
- Zain Ahmad
- Zakaria Ahmed
- Zakaria Andee Dzulkarnaen
- Zakaria Mohd Zaim
- Zalloum Jihad
- Zamanbandhon Bushra
- Zambon Mattia
- Zapsalis Konstantinos
- Zargar Kamran
- Zarzour Mohamed A
- Zeng Raymond
- Zeng Raymond
- Zengin Kagan
- Zertuche Juventino Tadeo Guerrero
- Zhang Caitlin
- Zhang Edward
- Zhang Shane
- Zhang Yichi
- Zhao Hailin
- Zheng Helen
- Zhou Karen
- Zhou Yida
- Ziergiebel Felix
- Zou Peishan
- Zuylekom Kate Van
- Zuylekom Katie Van
- Zwain Yasir Adnan
- Zyul'korneeva Sof'ya
- Aladna Abdallah
- Aljoumaa Abdullah
- Nawfal Hamdi
- Niazi Ammar
- Publication venue
- Publication date
- 01/01/2024
- Field of study
Background: Balancing opioid stewardship and the need for adequate analgesia following discharge after surgery is challenging. This study aimed to compare the outcomes for patients discharged with opioid versus opioid-free analgesia after common surgical procedures.Methods: This international, multicentre, prospective cohort study collected data from patients undergoing common acute and elective general surgical, urological, gynaecological, and orthopaedic procedures. The primary outcomes were patient-reported time in severe pain measured on a numerical analogue scale from 0 to 100% and patient-reported satisfaction with pain relief during the first week following discharge. Data were collected by in-hospital chart review and patient telephone interview 1 week after discharge.Results: The study recruited 4273 patients from 144 centres in 25 countries; 1311 patients (30.7%) were prescribed opioid analgesia at discharge. Patients reported being in severe pain for 10 (i.q.r. 1-30)% of the first week after discharge and rated satisfaction with analgesia as 90 (i.q.r. 80-100) of 100. After adjustment for confounders, opioid analgesia on discharge was independently associated with increased pain severity (risk ratio 1.52, 95% c.i. 1.31 to 1.76; P < 0.001) and re-presentation to healthcare providers owing to side-effects of medication (OR 2.38, 95% c.i. 1.36 to 4.17; P = 0.004), but not with satisfaction with analgesia (beta coefficient 0.92, 95% c.i. -1.52 to 3.36; P = 0.468) compared with opioid-free analgesia. Although opioid prescribing varied greatly between high-income and low- and middle-income countries, patient-reported outcomes did not.Conclusion: Opioid analgesia prescription on surgical discharge is associated with a higher risk of re-presentation owing to side-effects of medication and increased patient-reported pain, but not with changes in patient-reported satisfaction. Opioid-free discharge analgesia should be adopted routinely
Chemically Precise Glycoengineering Improves Human Insulin
- Author
- Amy H. Tran (4059022)
- Chen Zeng (34338)
- Daniel R Gulbranson (4636495)
- Jingshi Shen (1510480)
- Liqun Chen (325324)
- Patrick K. Chaffey (4636501)
- Theo N. Koelsch (4059025)
- Wei Liang (26352)
- Xiaoyang Guan (1867630)
- Xinfeng Wang (575501)
- Xiuli Wei (4636498)
- Yan Ouyang (342797)
- Yaohao Li (2581240)
- Yuan Ruan (116762)
- Zhongping Tan (1867627)
- Publication venue
- Publication date
- Field of study
Diabetes
is a leading cause of death worldwide and results in over
3 million annual deaths. While insulin manages the disease well, many
patients fail to comply with injection schedules, and despite significant
investment, a more convenient oral formulation of insulin is still
unavailable. Studies suggest that glycosylation may stabilize peptides
for oral delivery, but the demanding production of homogeneously glycosylated
peptides has hampered transition into the clinic. We report here the
first total synthesis of homogeneously glycosylated insulin. After
characterizing a series of insulin glycoforms with systematically
varied O-glycosylation sites and structures, we demonstrate that O-mannosylation
of insulin B-chain Thr27 reduces the peptide’s susceptibility
to proteases and self-association, both critical properties for oral
dosing, while maintaining full activity. This work illustrates the
promise of glycosylation as a general mechanism for regulating peptide
activity and expanding its therapeutic use
Genotypic variants at 2q33 and risk of esophageal squamous cell carcinoma in China: A meta-analysis of genome-wide association studies
- Author
- 1000 Genomes Project Consortium
- Abnet
- Ai-Fang Ji
- Ai-Li Li
- Alisa M. Goldstein
- Amy Hutchinson
- Bao-Ping Chen
- Barrett
- Bin Liu
- Brown
- Carol A. Giffen
- Chang-Dong Lu
- Chang-Wei Feng
- Chao Yuan
- Chaoyu Wang
- Charles C. Chung
- Chen
- Christian C. Abnet
- Chung
- Couch
- Cox
- Dan Li
- Dong Xie
- Dong-Yun Zhang
- En-Min Li
- Er-Tao Guo
- Fearnhead
- Fearnhead
- Feng Li
- Fu-Bao Chang
- Fu-Guo Zhu
- Fu-Sheng Gao
- Fu-You Zhou
- Gao
- Gao-Fu Zhang
- Grishin
- Guang-Yan Lei
- Guo-Lan Xing
- Guo-Shun Ma
- Hadano
- Hai Liu
- Hai-Lin Liu
- Haiman
- Hinkes
- Hong-Lei Li
- Hong-Li Lin
- Howie
- Hu
- Ilyar Sheyhidin
- Jeff Yuenger
- Ji-Li Chen
- Ji-Li Cui
- Ji-Lin Li
- Jia Chang
- Jia Huang
- Jian-Jun Miao
- Jian-Min Yuan
- Jian-Po Wang
- Jian-Ting Zhao
- Jian-Wei Kul
- Jian-Xue Yang
- Jiang-Man Li
- Jie Chen
- Jin Wang
- Jin-Chang Wei
- Jin-Cheng Dong
- Jin-Hu Fan
- Jin-Sheng Wang
- Jing Huang
- Jing Liu
- Jing-Jing Han
- Jing-Li Ren
- Joseph F. Fraumeni
- Jun-Yan Hong
- Kai Yu
- Kevin B. Jacobs
- Khor
- Lan
- Laurie Burdett
- Lei Fan
- Li
- Li Guo
- Li Wang
- Li-Dong Wang
- Li-Yan Xu
- Lian-Qun Zhang
- Liang Wang
- Liang-Dan Sun
- Linda M. Liao
- Ling Yuan
- Liu-Qin Yang
- Long-Qi Chen
- Lu-Wen Wang
- Luna
- Margaret A. Tucker
- Maxwell P. Lee
- Meredith Yeager
- Min Han
- Min Liu
- Ming Guo
- Minichiello
- Nan Hu
- Neal D. Freedman
- Ng
- Parkin
- Peng Zhang
- Philip R. Taylor
- Ping Tao
- Qi Zhou
- Qin-Xian Zhang
- Qing-Peng Kong
- Qirenwang Qige
- Ran Wang
- Sa Tang
- Sanford M. Dawsey
- She-Gan Gao
- Sheng-Li Zhou
- Shu-Qing Chen
- Shu-Wei Ren
- Sin-Yong Lian
- Son
- Song-Liang Qiu
- Stephen J. Chanock
- Stephens
- Sun
- Tai-Jing Liu
- Ti Ding
- Tian-Yun Wang
- Tran
- Umar
- Wan-Cai Yang
- Wan-Li Yin
- Wang
- Wang
- Wei Zhang
- Wei Zhang
- Wei Zheng
- Wei-Peng Wang
- Wen-Bin Yue
- Wen-Jing Fu
- Wen-Jun Yang
- Wen-Liang Zhu
- Wen-Yan Cui
- William Wheeler
- Wong-Ho Chow
- Woon-Puay Koh
- Wu Wei
- Xi Chen
- Xia Yang
- Xian-Bo Zuo
- Xian-Chang Li
- Xian-Zeng Wang
- Xiang Zhuang
- Xiao-Ou Shu
- Xiao-Shan Feng
- Xin Song
- Xin-Ying Jian
- Xiu-Feng Yang
- Xiu-Min Li
- Xiu-Qin Peng
- Xue
- Xue-Jun Zhang
- Xue-Ke Zhao
- Xue-Min Li
- Xue-Pin Fan
- Ya-Li Liu
- Yan Jin
- Yan Li
- Yan-Long Hu
- Yan-Rui Zhang
- Yi-Ming Mao
- Yin
- Yin Li
- Ying-Fa Zhou
- Yong-Bing Xiang
- You-Lin Qiao
- Yu Liu
- Yu-Tang Gao
- Yuan Yuan
- Yuan-Fang Chen
- Yue Wu
- Ze-Zhong Tang
- Zeng-Lin Fan
- Zhao
- Zhaoming Wang
- Zhi-Cai Liu
- Zhi-Chao Hou
- Zhi-Gang Guo
- Zhi-Guo Chen
- Zhi-Qin Bao
- Zhi-Qing Yuan
- Zhi-Yong Wu
- Zhong-Min Fan
- Zhou Wang
- Zi-Ming Dong
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/05/2012
- Field of study
10.1093/hmg/dds029Human Molecular Genetics2192132-2141HMGE
A review of methods for subtyping Yersinia pestis: From phenotypes to whole genome sequencing
- Author
- Achtman
- Achtman
- Adair
- Amy J. Vogler
- Anisimov
- Antonation
- Auerbach
- Baker
- Barros
- Barros
- Birdsell
- Bos
- Bos
- Buchrieser
- Cabanel
- Cavalcanti
- Chain
- Chain
- Chu
- Ciammaruconi
- Ciammaruconi
- Ciammaruconi
- Colman
- Cui
- Cui
- Cui
- Cummings
- Cáceres
- Dai
- Dai
- David M. Wagner
- Deng
- Devignat
- Dong
- Drancourt
- Drancourt
- Drancourt
- Duan
- Eppinger
- Eppinger
- Eppinger
- Eroshenko
- Galimand
- Garcia
- Gibbons
- Girard
- Glenn
- Guiyoule
- Guiyoule
- Haensch
- Hai
- Harbeck
- Hinchliffe
- Huang
- Huang
- Jansen
- Keim
- Keim
- Keim
- Kiefer
- Kingston
- Klevytska
- Kotetishvili
- Le Flèche
- Leal
- Li
- Li
- Li
- Li
- Li
- Liang
- Liang
- Lindler
- Losada
- Lowell
- Lowell
- Lucier
- Mahale
- Malou
- McAvin
- Meacham
- Morelli
- Motin
- Oliveira
- Parkhill
- Paul Keim
- Pearson
- Pearson
- Perry
- Platonov
- Pourcel
- Pourcel
- Power
- Pusch
- Qi
- Radnedge
- Radnedge
- Rakin
- Raoult
- Revazishvili
- Riehm
- Rotz
- Schuenemann
- Seifert
- Shen
- Shi
- Song
- Sun
- Torrea
- Touchman
- Tran
- Tran
- Trebesius
- Tsangaras
- Turingan
- Vergnaud
- Vergnaud
- Vogler
- Vogler
- Vogler
- Vogler
- Wagner
- Wang
- Wang
- Wei
- Wiechmann
- Wiechmann
- Yan
- Yang
- Zhang
- Zhang
- Zhou
- Zhou
- Zhou
- Publication venue
- 'Elsevier BV'
- Publication date
- Field of study
Joint analysis of three genome-wide association studies of esophageal squamous cell carcinoma in Chinese populations
- Author
- AD Coviello
- Ai-Li Li
- Ai-Qun Wu
- AL Sherborne
- Alisa M Goldstein
- Amy Hutchinson
- AP Boyle
- Bao-Chi Liu
- Bao-Gen Ma
- Bei Li
- Bin Liu
- C Wu
- C Wu
- Carol Giffen
- CC Abnet
- CC Abnet
- Chang-Wei Feng
- Changdong Lu
- Chaoyu Wang
- Charles C Chung
- Chen Wu
- Christian C Abnet
- Chuanhai Guo
- Chunling Liu
- CS Yang
- Dianke Yu
- Dong Xie
- Dong-Yun Zhang
- Dongxin Lin
- DT Bishop
- En-Min Li
- Er-Tao Guo
- F Gu
- F Kamangar
- Fang-Heng Zhu
- Feng Li
- Fu-You Zhou
- GD Tran
- Guang-Yan Lei
- Guangfu Jin
- Guo Yuan
- Guo-Lan Xing
- H Ishikawa
- Haijun Yang
- Hong-Li Lin
- Hong-Zhang Hao
- Hongbing Shen
- Hui Meng
- Ilyar Sheyhidin
- Jeff Yuenger
- Ji-Li Cui
- Ji-Lin Li
- Jian-Min Yuan
- Jian-Wei Ku
- Jiang Chang
- Jianhua Fu
- Jie He
- Jin Wang
- Jin-Hu Fan
- Jing Liu
- Jing-Jing Han
- Jing-Li Ren
- Joseph F Fraumeni
- Jun-Yan Hong
- JW Han
- JX Bei
- Kai Yu
- Kan Zhai
- Kevin Jacobs
- Laurie Burdette
- LD Wang
- LD Ward
- Li Sun
- Li Wang
- Li-Dong Wang
- Li-Sha Chen
- Liang Wang
- Liang-Dan Sun
- Linda Liao
- Ling Yuan
- Liu-Qin Yang
- Lixuan Wei
- Long-Qi Chen
- Lu-Wen Wang
- Margaret A Tucker
- Maxwell P Lee
- Mei Zhang
- Meredith Yeager
- Min Han
- Mitchell Gail
- N Hu
- Nan Hu
- ND Freedman
- Neal D Freedman
- P Eck
- P Rajaraman
- Peng Zhang
- Peter Kraft
- Philip R Taylor
- Q Lan
- Qi-De Bao
- Qimin Zhan
- Qing-Peng Kong
- Qirenwang Qige
- QM Wang
- Ran Wang
- RB Kennedy
- S Li
- S Remeseiro
- Sa Tang
- Sanford M Dawsey
- She-Gan Gao
- Sheng-Li Zhou
- Shu-Qing Chen
- Shu-Wei Ren
- SI Berndt
- SL Slager
- SS Mirvish
- Stephen J Chanock
- Tangchun Wu
- Teng Ma
- Ti Ding
- V Enciso-Mora
- Wan-Cai Yang
- Wei Zhang
- Wei Zheng
- Wei-Xing Zhao
- Weihua Jia
- Wen Tan
- Wen-Bin Yue
- Wen-Jun Yang
- William A Wheeler
- Woon-Puay Koh
- Wu Wei
- Xi Chen
- Xian-Bo Zuo
- Xiao Liu
- Xiao-Hang Zhao
- Xiao-Ou Shu
- Xiao-Shan Feng
- Xiaoping Miao
- Xin Song
- Xin-Min Li
- Xiu-Min Li
- Xiu-Qing Peng
- Xue-Jun Zhang
- Xue-Ke Zhao
- Xue-Min Li
- Xue-Na Han
- Xue-Ping Fan
- Y Okada
- Ya-Li Liu
- Yan Li
- Yan Qiao
- Yan-Long Hu
- Yan-Rui Zhang
- Yang Ke
- Yi-Min Mao
- Yifeng Zhou
- Yin Li
- Ying Huang
- Ying-Fa Zhou
- Yixin Zeng
- Yong-Bing Xiang
- You-Lin Qiao
- Yu Liu
- Yu Liu
- Yu-Hua Yang
- Yu-Tang Gao
- Yuan Yuan
- Z Su
- Ze-Zhong Tang
- Zhaoming Wang
- Zhi-Chao Hou
- Zhi-Qing Yuan
- Zhibin Hu
- Zhihua Liu
- Zhonghu He
- Zhou Wang
- Zong-Min Fan
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
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- Li
- Li
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- Publication date
- 01/01/2015
- Field of study
Recommended from our members
Thank You Reviewers
- Author
- Adams Susan M
- Agarwala Tanuja
- Akbar Hammad
- Andrews Martha
- Ang Soon
- Arnold Stewart
- Ascigil Semra
- Bachrach Dan
- Bacon Nick
- Balkin David
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- Publication venue
- Publication date
- 01/02/2009
- Field of study
Reproducibility of fluorescent expression from engineered biological constructs in E. coli
- Author
- Abdirakhmanova Altynay
- Abtahi Kimia
- Acar Muradýye
- Adams David
- Adrian Julia Anna
- Afzal Remsha
- Agarwal Yash
- Ahsan Fasih M.
- Ainsworth Catherine
- Akan Madina
- Aktas Muhammed Fatih
- Al Azhar Muhammad
- Altintas Ali
- Ananda Cindy Suci
- Ananos Mathilde
- Ang Timothy
- Anlind Nils
- Appletion Evan
- Appleton Evan
- Arkhipenko Alexander
- Arroyo María Fernanda Sánchez
- Aruanno Marion
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- Aubert Pauline
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- Van Deuren Vincent
- Van Hese Laura
- Van Leeuwen Esther
- Van Raaphorst Renske
- Van Rijn Erwin
- Van Rosmalen Rik
- Van Smeden Laura
- Van Tiel Nina
- Van Wonterghem Laetitia
- Van't Hof Max
- Vandebroek Laurens
- Vandendaele Amelie
- Vasconcelos Graziele
- Vazquez Claudia Melissa Guerra
- Veening Jan Willem
- Verschooten Leen
- Vij Panya
- Vilar Marta Vazquez
- Viola John
- Von Chamier Lucas
- Von Kügelgen Nicolai
- Wadhams George
- Wahab Adam
- Walsh Kevin
- Wang Boxiang
- Wang Haotian
- Wang Lena
- Wang Weiyi
- Wang Xuan
- Wang Yingqi
- Wang Yushen
- Watkins Ella
- Weber Susanne
- Wehle Devin
- Wehrs Maren
- Wei Huang
- Wei Yang
- Wei Yibing
- Wellinger Lisa
- Wellman Rachel
- Weme Ruud Detert Oude
- Werchau Niels
- Westwood Georgina
- Wieden Hans Joachim
- Wieske Lianne
- Witarto Arief Budi
- Wojcik Emilia
- Wolter Moritz
- Wronska Anna
- Wu Fan
- Wu Guozhao
- Wu Qi
- Wu Wen Ying
- Xiang Daniel
- Xiangyue Hu
- Xiaojing Li
- Xiaomei Lin
- Xiaoran Yang
- Xu Zixuan
- Xunxun Luo
- Yamazaki Yuta
- Yan Jieyu
- Yan Keji
- Yan Ming
- Yan Xiaoshan
- Yang Kang
- Yang Yang
- Yang Yunjun
- Yao Ningning
- Yasunishi Shuhei
- Yen Zen Zen
- Yilmaz Mustafa
- Ying Oscar
- Young Hannah
- Young Paul
- Yousaf Waqar
- Yu Michelle
- Yuanzhan Yang
- Yuksel Seniz
- Yulianti
- Yushan Zhang
- Zach Pavel
- Zadey Siddhesh
- Zampronio Danilo Keiji
- Zaworski Julie
- Zeng Zhi
- Zhailauova Azhar
- Zhan Yi
- Zhang Haoqian Myelin
- Zhang Qianbin
- Zhang Ruihua
- Zhang Tangduo
- Zhang Zhaoran
- Zhao Hongxia
- Zhao Ruixue
- Zhaosen Wen
- Zhou Yineng
- Zhu Iowis
- Zhu Kwan Kwan
- Zimmermann Arne
- Zimont Allison
- Zixuan Erinn Sim
- Ávila Alejandro Gómez
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- 01/03/2016
- Field of study
We present results of the first large-scale interlaboratory study carried out in synthetic biology, as part of the 2014 and 2015 International Genetically Engineered Machine (iGEM) competitions. Participants at 88 institutions around the world measured fluorescence from three engineered constitutive constructs in E. coli. Few participants were able to measure absolute fluorescence, so data was analyzed in terms of ratios. Precision was strongly related to fluorescent strength, ranging from 1.54-fold standard deviation for the ratio between strong promoters to 5.75-fold for the ratio between the strongest and weakest promoter, and while host strain did not affect expression ratios, choice of instrument did. This result shows that high quantitative precision and reproducibility of results is possible, while at the same time indicating areas needing improved laboratory practices.Peer reviewe