238 research outputs found

    Too Tired to Think Outside the Box? An Analysis of Ego Depletion\u27s Effects on Creativity

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    Recent research suggests that complex tasks that require self-control to complete, such as strenuous tests or complicated decisions, put a strain on the limited resource known as the ego. The ego is thought to be a kind of mental energy reserve that can be depleted with use. Previous studies have shown that, not only is it possible to deplete the ego, but this depletion leads to poor performance on various later tasks involving skills such as decision making, cognitive extrapolation, reasoning, and self-control. Two models in particular have gained support recently: the resource model –involving blood glucose– and the trade-off model – involving distribution of attention. Because both creativity and the ego are thought to be biologically based and because cognitive flexibility, which has been shown to be highly correlated with creativity, seems to require a fairly high level of processing like other processes on which ego depletion has been shown to have a negative effect, it is reasonable to suggest that ego depletion would cause a decrease in creativity as well

    Pursuing Clean Energy Equitably

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    This paper explores the opportunities for a ‘just transition’ to low carbon and sustainable energy systems; one that addresses the current inequities in the distribution of energy benefits and their human and ecological costs. In order to prioritize policies that address energy poverty alleviation and sustainability concerns, national action and higher levels of international cooperation and coordination are required to steer public policy towards a broader range of public interests. This also implies re-directing the vast sums of private energy finance that currently serve a narrow set of interests. This paper considers how national and global energy governance must adapt and change to ensure a just transition to low carbon and sustainable energy systems. Creating a low carbon and sustainable energy transition will face significant challenges in overcoming opposition from a broad array of interest groups. The challenges of guiding a just transition are amplified by the relinquishing of government control over the energy sector in many countries and the current weak and fragmented state of global energy governance. The necessary changes in energy decision making will entail complex trade-offs and rebound effects that make strong, participatory and transparent institutional arrangements essential in order to govern such challenges equitably. In this respect, procedural justice is critical to achieving distributive justice and to creating a simultaneously rapid, sustainable and equitable transition to clean energy futures

    Distributed Disdrometer and Rain Gauge Measurement Infrastructure Developed for GPM Ground Validation

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    Global Precipitation Mission (GPM)retrieval algorithm validation requires datasets characterizing the 4-D structure, variability, and correlation properties of hydrometeor particle size distributions (PSD) and accumulations over satellite fields of view (FOV;<10 km). Collection of this data provides a means to assess retrieval errors related to beam filling and algorithm PSD assumptions. Hence, GPM Ground Validation is developing a deployable network of precipitation gauges and disdrometers to provide fine-scale measurements of PSD and precipitation accumulation variability. These observations will be combined with dual-frequency, polarimetric, and profiling radar data in a bootstrapping fashion to extend validated PSD measurements to a large coverage domain. Accordingly, a total of 24 Parsivel disdrometers(PD), 5 3rd-generation 2D Video Disdrometers (2DVD), 70 tipping bucket rain gauges (TBRG),9 weighing gauges, 7 Hot-Plate precipitation sensors (HP), and 3 Micro Rain Radars (MRR) have been procured. In liquid precipitation the suite of TBRG, PD and 2DVD instruments will quantify a broad spectrum of rain rate and PSD variability at sub-kilometer scales. In the envisioned network configuration 5 2DVDs will act as reference points for 16 collocated PD and TBRG measurements. We find that PD measurements provide similar measures of the rain PSD as observed with collocated 2DVDs (e.g., D0, Nw) for rain rates less than 15 mm/hr. For heavier rain rates we will rely on 2DVDs for PSD information. For snowfall we will combine point-redundant observations of SWER distributed over three or more locations within a FOV. Each location will contain at least one fenced weighing gauge, one HP, two PDs, and a 2DVD. MRRs will also be located at each site to extend the measurement to the column. By collecting SWER measurements using different instrument types that employ different measurement techniques our objective is to separate measurement uncertainty from natural variability in SWER and PSD. As demonstrated using C3VP polarimetric radar, gauge, and 2DVD/PD datasets these measurements can be combined to bootstrap an area wide SWER estimate via constrained modification of density-diameter and radar reflectivity-snowfall relationships. These data will be combined with snowpack, airborne microphysics, radar, radiometer, and tropospheric sounding data to refine GPM snowfall retrievals. The gauge and disdrometer instruments are being developed to operate autonomously when necessary using solar power and wireless communications. These systems will be deployed in numerous field campaigns through 2016. Planned deployment of these systems include field campaigns in Finland (2010), Oklahoma (2011), Canada (2012) and North Carolina (2013). GPM will also deploy 20 pairs of TBRGs within a 25 km2 region along the Virginia coast under NASA NPOL radar coverage in order to quantify errors in point-area rainfall measurements

    Alabama Ground Operations during the Deep Convective Clouds and Chemistry Experiment

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    The Deep Convective Clouds and Chemistry (DC3) field campaign investigates the impact of deep, midlatitude convective clouds, including their dynamical, physical and lighting processes, on upper tropospheric composition and chemistry. DC3 science operations took place from 14 May to 30 June 2012. The DC3 field campaign utilized instrumented aircraft and ground ]based observations. The NCAR Gulfstream ]V (GV) observed a variety of gas ]phase species, radiation and cloud particle characteristics in the high ]altitude outflow of storms while the NASA DC ]8 characterized the convective inflow. Groundbased radar networks were used to document the kinematic and microphysical characteristics of storms. In order to study the impact of lightning on convective outflow composition, VHF ]based lightning mapping arrays (LMAs) provided detailed three ]dimensional measurements of flashes. Mobile soundings were utilized to characterize the meteorological environment of the convection. Radar, sounding and lightning observations were also used in real ]time to provide forecasting and mission guidance to the aircraft operations. Combined aircraft and ground ]based observations were conducted at three locations, 1) northeastern Colorado, 2) Oklahoma/Texas and 3) northern Alabama, to study different modes of deep convection in a variety of meteorological and chemical environments. The objective of this paper is to summarize the Alabama ground operations and provide a preliminary assessment of the ground ]based observations collected over northern Alabama during DC3. The multi ] Doppler, dual ]polarization radar network consisted of the UAHuntsville Advanced Radar for Meteorological and Operational Research (ARMOR), the UAHuntsville Mobile Alabama X ]band (MAX) radar and the Hytop (KHTX) Weather Surveillance Radar 88 Doppler (WSR ]88D). Lightning frequency and structure were observed in near real ]time by the NASA MSFC Northern Alabama LMA (NALMA). Pre ]storm and inflow proximity soundings were obtained with the UAHuntsville mobile sounding unit and the Redstone Arsenal (QAG) morning sounding

    Court Cases, Cultural Expertise and ´Female Genital Mutilation' in Europe

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    This chapter discusses adjudication, expertise, and cultural difference as it appears in criminal court cases concerning female genital cutting (FGM) in the EU, as reported in a 2015 comparative overview. It begins with the distinction between typical and atypical FGM cases; a distinction that connects court cases to the cultural realities of the practicing communities, suggesting that the lack of cultural knowledge can cause unnecessary suffering to families and/or individuals who wrongly undergo prosecution in alleged FGM cases. A contrario, the intervention of experts in FGM court cases could be a positive approach to assessing the legitimacy of public intervention in certain cases

    Generalized Connective Tissue Disease in Crtap-/- Mouse

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    Mutations in CRTAP (coding for cartilage-associated protein), LEPRE1 (coding for prolyl 3-hydroxylase 1 [P3H1]) or PPIB (coding for Cyclophilin B [CYPB]) cause recessive forms of osteogenesis imperfecta and loss or decrease of type I collagen prolyl 3-hydroxylation. A comprehensive analysis of the phenotype of the Crtap-/- mice revealed multiple abnormalities of connective tissue, including in the lungs, kidneys, and skin, consistent with systemic dysregulation of collagen homeostasis within the extracellular matrix. Both Crtap-/- lung and kidney glomeruli showed increased cellular proliferation. Histologically, the lungs showed increased alveolar spacing, while the kidneys showed evidence of segmental glomerulosclerosis, with abnormal collagen deposition. The Crtap-/- skin had decreased mechanical integrity. In addition to the expected loss of proline 986 3-hydroxylation in α1(I) and α1(II) chains, there was also loss of 3Hyp at proline 986 in α2(V) chains. In contrast, at two of the known 3Hyp sites in α1(IV) chains from Crtap-/- kidneys there were normal levels of 3-hydroxylation. On a cellular level, loss of CRTAP in human OI fibroblasts led to a secondary loss of P3H1, and vice versa. These data suggest that both CRTAP and P3H1 are required to maintain a stable complex that 3-hydroxylates canonical proline sites within clade A (types I, II, and V) collagen chains. Loss of this activity leads to a multi-systemic connective tissue disease that affects bone, cartilage, lung, kidney, and skin

    Tamiflu-Resistant but HA-Mediated Cell-to-Cell Transmission through Apical Membranes of Cell-Associated Influenza Viruses

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    The infection of viruses to a neighboring cell is considered to be beneficial in terms of evasion from host anti-virus defense systems. There are two pathways for viral infection to “right next door”: one is the virus transmission through cell-cell fusion by forming syncytium without production of progeny virions, and the other is mediated by virions without virus diffusion, generally designated cell-to-cell transmission. Influenza viruses are believed to be transmitted as cell-free virus from infected cells to uninfected cells. Here, we demonstrated that influenza virus can utilize cell-to-cell transmission pathway through apical membranes, by handover of virions on the surface of an infected cell to adjacent host cells. Live cell imaging techniques showed that a recombinant influenza virus, in which the neuraminidase gene was replaced with the green fluorescence protein gene, spreads from an infected cell to adjacent cells forming infected cell clusters. This type of virus spreading requires HA activation by protease treatment. The cell-to-cell transmission was also blocked by amantadine, which inhibits the acidification of endosomes required for uncoating of influenza virus particles in endosomes, indicating that functional hemagglutinin and endosome acidification by M2 ion channel were essential for the cell-to-cell influenza virus transmission. Furthermore, in the cell-to-cell transmission of influenza virus, progeny virions could remain associated with the surface of infected cell even after budding, for the progeny virions to be passed on to adjacent uninfected cells. The evidence that cell-to-cell transmission occurs in influenza virus lead to the caution that local infection proceeds even when treated with neuraminidase inhibitors

    Search for dark matter produced in association with bottom or top quarks in √s = 13 TeV pp collisions with the ATLAS detector

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    A search for weakly interacting massive particle dark matter produced in association with bottom or top quarks is presented. Final states containing third-generation quarks and miss- ing transverse momentum are considered. The analysis uses 36.1 fb−1 of proton–proton collision data recorded by the ATLAS experiment at √s = 13 TeV in 2015 and 2016. No significant excess of events above the estimated backgrounds is observed. The results are in- terpreted in the framework of simplified models of spin-0 dark-matter mediators. For colour- neutral spin-0 mediators produced in association with top quarks and decaying into a pair of dark-matter particles, mediator masses below 50 GeV are excluded assuming a dark-matter candidate mass of 1 GeV and unitary couplings. For scalar and pseudoscalar mediators produced in association with bottom quarks, the search sets limits on the production cross- section of 300 times the predicted rate for mediators with masses between 10 and 50 GeV and assuming a dark-matter mass of 1 GeV and unitary coupling. Constraints on colour- charged scalar simplified models are also presented. Assuming a dark-matter particle mass of 35 GeV, mediator particles with mass below 1.1 TeV are excluded for couplings yielding a dark-matter relic density consistent with measurements

    Impact of COVID-19 on cardiovascular testing in the United States versus the rest of the world

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    Objectives: This study sought to quantify and compare the decline in volumes of cardiovascular procedures between the United States and non-US institutions during the early phase of the coronavirus disease-2019 (COVID-19) pandemic. Background: The COVID-19 pandemic has disrupted the care of many non-COVID-19 illnesses. Reductions in diagnostic cardiovascular testing around the world have led to concerns over the implications of reduced testing for cardiovascular disease (CVD) morbidity and mortality. Methods: Data were submitted to the INCAPS-COVID (International Atomic Energy Agency Non-Invasive Cardiology Protocols Study of COVID-19), a multinational registry comprising 909 institutions in 108 countries (including 155 facilities in 40 U.S. states), assessing the impact of the COVID-19 pandemic on volumes of diagnostic cardiovascular procedures. Data were obtained for April 2020 and compared with volumes of baseline procedures from March 2019. We compared laboratory characteristics, practices, and procedure volumes between U.S. and non-U.S. facilities and between U.S. geographic regions and identified factors associated with volume reduction in the United States. Results: Reductions in the volumes of procedures in the United States were similar to those in non-U.S. facilities (68% vs. 63%, respectively; p = 0.237), although U.S. facilities reported greater reductions in invasive coronary angiography (69% vs. 53%, respectively; p < 0.001). Significantly more U.S. facilities reported increased use of telehealth and patient screening measures than non-U.S. facilities, such as temperature checks, symptom screenings, and COVID-19 testing. Reductions in volumes of procedures differed between U.S. regions, with larger declines observed in the Northeast (76%) and Midwest (74%) than in the South (62%) and West (44%). Prevalence of COVID-19, staff redeployments, outpatient centers, and urban centers were associated with greater reductions in volume in U.S. facilities in a multivariable analysis. Conclusions: We observed marked reductions in U.S. cardiovascular testing in the early phase of the pandemic and significant variability between U.S. regions. The association between reductions of volumes and COVID-19 prevalence in the United States highlighted the need for proactive efforts to maintain access to cardiovascular testing in areas most affected by outbreaks of COVID-19 infection
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