514 research outputs found
Platform adaptive trial of novel antivirals for early treatment of COVID-19 In the community (PANORAMIC): protocol for a randomised, controlled, open-label, adaptive platform trial of community novel antiviral treatment of COVID-19 in people at increased risk of more severe disease
- Author
- Allen Julie
- Andersson Monique I
- Barrett Sarah
- Bateman Clare
- Benysek Magdalena
- Breuer Judith
- Butler Christopher C
- Carson-Stevens Andrew
- Chalk Jem
- Coates Maria
- Cureton Lucy
- Davies Jennifer
- Dobson Melissa
- Dorward Jienchi
- Evans Philip
- Francis Nick
- Gbinigie Oghenekome
- Hadley Elizabeth
- Harris Victoria
- Hart Nigel
- Hayward Gail
- Hobbs Richard
- Holmes Jane
- Hood Kerenza
- Jani Bhautesh
- Khoo Saye
- Koshkouei Mona
- Lavallee Layla
- Little Paul
- Lowe David M
- Lown Mark
- Madden Tracie-Ann
- Marion Joe
- Nguyen-Van-Tam Jonathan
- Ogburn Emma
- Patel Mahendra
- Petrou Stavros
- Png May Ee
- Rahman Najib
- Raymundo-Wood Ivy
- Richards Duncan
- Rutter Heather
- Saville Benjamin R
- Standing Joseph F
- Thomas Nicholas PB
- Ustianowski Andrew
- van Hecke Oliver
- Yu Ly-Mee
- Publication venue
- 'BMJ'
- Publication date
- 01/07/2023
- Field of study
Introduction: There is an urgent need to determine the safety, effectiveness and cost-effectiveness of novel antiviral treatments for COVID-19 in vaccinated patients in the community at increased risk of morbidity and mortality from COVID-19.
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Methods and analysis: PANORAMIC is a UK-wide, open-label, prospective, adaptive, multiarm platform, randomised clinical trial that evaluates antiviral treatments for COVID-19 in the community. A master protocol governs the addition of new antiviral treatments as they become available, and the introduction and cessation of existing interventions via interim analyses. The first two interventions to be evaluated are molnupiravir (Lagevrio) and nirmatrelvir/ritonavir (Paxlovid). Eligibility criteria: community-dwelling within 5 days of onset of symptomatic COVID-19 (confirmed by PCR or lateral flow test), and either (1) aged 50 years and over, or (2) aged 18–49 years with qualifying comorbidities. Registration occurs via the trial website and by telephone. Recruitment occurs remotely through the central trial team, or in person through clinical sites. Participants are randomised to receive either usual care or a trial drug plus usual care. Outcomes are collected via a participant-completed daily electronic symptom diary for 28 days post randomisation. Participants and/or their Trial Partner are contacted by the research team after days 7, 14 and 28 if the diary is not completed, or if the participant is unable to access the diary. The primary efficacy endpoint is all-cause, non-elective hospitalisation and/or death within 28 days of randomisation. Multiple prespecified interim analyses allow interventions to be stopped for futility or superiority based on prespecified decision criteria. A prospective economic evaluation is embedded within the trial.
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Ethics and dissemination: Ethical approval granted by South Central–Berkshire REC number: 21/SC/0393; IRAS project ID: 1004274. Results will be presented to policymakers and at conferences, and published in peer-reviewed journals.
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Trial registration number: ISRCTN30448031; EudraCT number: 2021-005748-31
Extinction filters mediate the global effects of habitat fragmentation on animals
- Author
- Arroyo-Rodríguez Víctor
- Banks-Leite Cristina
- Barlow Jos
- Betts Matthew G.
- Eigenbrod Felix
- Ewers Robert M.
- Faria Deborah
- Fletcher Robert J.
- Hadley Adam S.
- Hawes Joseph E.
- Holt Robert D.
- Klingbeil Brian
- Kormann Urs
- Lens Luc
- Levi Taal
- Medina-Rangel Guido F.
- Melles Stephanie L.
- Mezger Dirk
- Morante-Filho José C.
- Orme C. David L.
- Peres Carlos A.
- Pfeifer Marion
- Phalan Benjamin T.
- Pidgeon Anna
- Possingham Hugh
- Ribeiro Danilo B.
- Ripple William J.
- Slade Eleanor M.
- Somarriba Eduardo
- Tobias Joseph A.
- Tylianakis Jason M.
- Urbina-Cardona J. Nicolás
- Valente Jonathon J.
- Watling James I.
- Wearn Oliver R.
- Wells Konstans
- Wolf Christopher
- Wood Eric
- Young Richard
- Publication venue
- 'American Association for the Advancement of Science (AAAS)'
- Publication date
- 01/01/2019
- Field of study
Habitat loss is the primary driver of biodiversity decline worldwide, but the effects of fragmentation (the spatial arrangement of remaining habitat) are debated. We tested the hypothesis that forest fragmentation sensitivity—affected by avoidance of habitat edges—should be driven by historical exposure to, and therefore species’ evolutionary responses to disturbance. Using a database containing 73 datasets collected worldwide (encompassing 4489 animal species), we found that the proportion of fragmentation-sensitive species was nearly three times as high in regions with low rates of historical disturbance compared with regions with high rates of disturbance (i.e., fires, glaciation, hurricanes, and deforestation). These disturbances coincide with a latitudinal gradient in which sensitivity increases sixfold at low versus high latitudes. We conclude that conservation efforts to limit edges created by fragmentation will be most important in the world’s tropical forests
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The impact of the metabotropic glutamate receptor and other gene family interaction networks on autism.
- Author
- AGP Consortium
- Almeida Joana
- Anagnostou Evdokia
- Anney Richard
- Bacchelli Elena
- Bailey Anthony
- Baird Gillian
- Battaglia Agatino
- Bernier Raphael
- Betancur Catalina
- Bolshakova Nadia
- Bolton Patrick
- Bourgeron Thomas
- Brennan Sean
- Buxbaum Joseph
- Bölte Sven
- Café Cátia
- Casey Jillian
- Chiocchetti Andreas
- Conceição Inês
- Connolly John
- Conroy Judith
- Cook Edwin
- Coon Hilary
- Correia Catarina
- Cuccaro Michael
- Dawson Geraldine
- De Jonge Maretha
- Delorme Richard
- Devlin Bernie
- Duketis Eftichia
- Duque Frederico
- Ennis Sean
- Fernandez Bridget
- Folstein Susan
- Freitag Christine
- Gallagher Louise
- Geschwind Daniel
- Gilbert John
- Gill Michael
- Gillberg Christopher
- Glessner Joseph
- Green Andrew
- Green Jonathan
- Guter Stephen
- Hadley Dexter
- Haines Jonathan
- Hakonarson Hakon
- Hallmayer Joachim
- Jacob Suma
- Kao Charlly
- Kim Cecilia
- Kini Akshata
- Klauck Sabine
- Klei Lambertus
- Kolevzon Alexander
- Le Couteur Ann
- Leboyer Marion
- Lord Catherine
- Maestrini Elena
- Magalhaes Tiago
- Mcgrew Susan
- Mentch Frank
- Merikangas Alison
- Minshew Nancy
- Mohamed-Hadley Alisha
- Monaco Anthony
- Mouga Susana
- Nurnberger John
- Oliveira Barbara
- Oliveira Guiomar
- Pagnamenta Alistair
- Parr Jeremy
- Paterson Andrew
- Pellegrino Renata
- Pericak-Vance Margaret
- Pinto Dalila
- Poustka Fritz
- Qiu Haijun
- Regan Regina
- Roberts Wendy
- Rogé Bernadette
- Schellenberg Gerard
- Scherer Stephen
- Soorya Latha
- Sutcliffe James
- Szatmari Peter
- Thomas Kelly
- Thompson Ann
- Van Engeland Herman
- Vazquez Lyam
- Vicente Astrid
- Vieland Veronica
- Vorstman Jacob
- Wallace Simon
- Wijsman Ellen
- Wittemeyer Kerstin
- Wu Zhi Liang
- Zwaigenbaum Lonnie
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2014
- Field of study
International audienceAlthough multiple reports show that defective genetic networks underlie the aetiology of autism, few have translated into pharmacotherapeutic opportunities. Since drugs compete with endogenous small molecules for protein binding, many successful drugs target large gene families with multiple drug binding sites. Here we search for defective gene family interaction networks (GFINs) in 6,742 patients with the ASDs relative to 12,544 neurologically normal controls, to find potentially druggable genetic targets. We find significant enrichment of structural defects (P≤2.40E-09, 1.8-fold enrichment) in the metabotropic glutamate receptor (GRM) GFIN, previously observed to impact attention deficit hyperactivity disorder (ADHD) and schizophrenia. Also, the MXD-MYC-MAX network of genes, previously implicated in cancer, is significantly enriched (P≤3.83E-23, 2.5-fold enrichment), as is the calmodulin 1 (CALM1) gene interaction network (P≤4.16E-04, 14.4-fold enrichment), which regulates voltage-independent calcium-activated action potentials at the neuronal synapse. We find that multiple defective gene family interactions underlie autism, presenting new translational opportunities to explore for therapeutic interventions
BIOFRAG: A new database for analysing BIOdiversity responses to forest FRAGmentation
- Author
- Arroyo Rodríguez Víctor
- Baeten Lander
- Banks Leite Cristina
- Barlow Jos
- Betts Matthew G.
- Bradley Andrew V.
- Brunet Joerg
- Cerezo Blandón Alexis Mauricio
- Cisneros Laura M.
- Collard Stuart
- Da Silva Motta Catarina
- Duguay Stephanie
- D´Cruze Neil
- Eggermont Hilde
- Eigenbrod Félix
- Ewers Robert M.
- Gardner Toby A.
- Hadley Adam S.
- Hanson Thor R.
- Hawes Joseph E.
- Heartsill Scalley Tamara
- Klingbeil Brian T.
- Kolb Annette
- Kormann Urs
- Kumar Sunil
- Lachat Thibault
- Lakeman Fraser Poppy
- Lantschner María Victoria
- Laurance William F.
- Leal Inara R.
- Lefebvre Veronique
- Lens Luc
- Marsh Charles J.
- Medina Rangel Guido F.
- Melles Stephanie
- Mezger Dirk
- Oldekop Johan A.
- Overal Williams L.
- Owen Charlotte
- Peres Carlos A.
- Pfeifer Marion
- Phalan Ben
- Pidgeon Anna Michle
- Pilia Oriana
- Possingham Hugh P.
- Possingham Max L.
- Raheem Dinarzarde C.
- Ribeiro Neto Jose D.
- Ribeiro Danilo B.
- Robinson Douglas W.
- Robinson Richard
- Rytwinski Trina
- Scherber Christoph
- Slade Eleanor M.
- Somarriba Eduardo
- Stouffer Philip C.
- Struebig Matthew J.
- Teja Tscharntke
- Tylianakis Jason M.
- Tyre Andrew J.
- Urbina Cardona Jose N.
- Vasconcelos Heraldo L.
- Wearn Oliver
- Wells Konstans
- Willig Michael R.
- Wood Eric
- Young Richard P.
- Publication venue
- 'Wiley'
- Publication date
- 01/05/2014
- Field of study
Habitat fragmentation studies are producing inconsistent and complex results across which it is nearly impossible to synthesise. Consistent analytical techniques can be applied to primary datasets, if stored in a flexible database that allows simple data retrieval for subsequent analyses. Method: We developed a relational database linking data collected in the field to taxonomic nomenclature, spatial and temporal plot attributes and further environmental variables (e.g. information on biogeographic region. Typical field assessments include measures of biological variables (e.g. presence, abundance, ground cover) of one species or a set of species linked to a set of plots in fragments of a forested landscape. Conclusion: The database currently holds records of 5792 unique species sampled in 52 landscapes in six of eight biogeographic regions: mammals 173, birds 1101, herpetofauna 284, insects 2317, other arthropods: 48, plants 1804, snails 65. Most species are found in one or two landscapes, but some are found in four. Using the huge amount of primary data on biodiversity response to fragmentation becomes increasingly important as anthropogenic pressures from high population growth and land demands are increasing. This database can be queried to extract data for subsequent analyses of the biological response to forest fragmentation with new metrics that can integrate across the components of fragmented landscapes. Meta-analyses of findings based on consistent methods and metrics will be able to generalise over studies allowing inter-comparisons for unified answers. The database can thus help researchers in providing findings for analyses of trade-offs between land use benefits and impacts on biodiversity and to track performance of management for biodiversity conservation in human-modified landscapes.Fil: Pfeifer, Marion. Imperial College London; Reino UnidoFil: Lefebvre, Veronique. Imperial College London; Reino UnidoFil: Gardner, Toby A.. Stockholm Environment Institute; SueciaFil: Arroyo Rodríguez, Víctor. Universidad Nacional Autónoma de México; MéxicoFil: Baeten, Lander. University of Ghent; BélgicaFil: Banks Leite, Cristina. Imperial College London; Reino UnidoFil: Barlow, Jos. Lancaster University; Reino UnidoFil: Betts, Matthew G.. State University of Oregon; Estados UnidosFil: Brunet, Joerg. Swedish University of Agricultural Sciences; SueciaFil: Cerezo Blandón, Alexis Mauricio. Universidad de Buenos Aires. Facultad de Agronomía. Departamento de Métodos Cuantitativos y Sistemas de Información; ArgentinaFil: Cisneros, Laura M.. University of Connecticut; Estados UnidosFil: Collard, Stuart. Nature Conservation Society of South Australia; AustraliaFil: D´Cruze, Neil. The World Society for the Protection of Animals; Reino UnidoFil: Da Silva Motta, Catarina. Ministério da Ciência, Tecnologia, Inovações. Instituto Nacional de Pesquisas da Amazônia; BrasilFil: Duguay, Stephanie. Carleton University; CanadáFil: Eggermont, Hilde. University of Ghent; BélgicaFil: Eigenbrod, Félix. University of Southampton; Reino UnidoFil: Hadley, Adam S.. State University of Oregon; Estados UnidosFil: Hanson, Thor R.. No especifíca;Fil: Hawes, Joseph E.. University of East Anglia; Reino UnidoFil: Heartsill Scalley, Tamara. United State Department of Agriculture. Forestry Service; Puerto RicoFil: Klingbeil, Brian T.. University of Connecticut; Estados UnidosFil: Kolb, Annette. Universitat Bremen; AlemaniaFil: Kormann, Urs. Universität Göttingen; AlemaniaFil: Kumar, Sunil. State University of Colorado - Fort Collins; Estados UnidosFil: Lachat, Thibault. Swiss Federal Institute for Forest; SuizaFil: Lakeman Fraser, Poppy. Imperial College London; Reino UnidoFil: Lantschner, María Victoria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca; Argentina. Instituto Nacional de Tecnología Agropecuaria. Centro Regional Patagonia Norte. Estación Experimental Agropecuaria San Carlos de Bariloche; ArgentinaFil: Laurance, William F.. James Cook University; AustraliaFil: Leal, Inara R.. Universidade Federal de Pernambuco; BrasilFil: Lens, Luc. University of Ghent; BélgicaFil: Marsh, Charles J.. University of Leeds; Reino UnidoFil: Medina Rangel, Guido F.. Universidad Nacional de Colombia; ColombiaFil: Melles, Stephanie. University of Toronto; CanadáFil: Mezger, Dirk. Field Museum of Natural History; Estados UnidosFil: Oldekop, Johan A.. University of Sheffield; Reino UnidoFil: Overal , Williams L.. Museu Paraense Emílio Goeldi. Departamento de Entomologia; BrasilFil: Owen, Charlotte. Imperial College London; Reino UnidoFil: Peres, Carlos A.. University of East Anglia; Reino UnidoFil: Phalan, Ben. University of Southampton; Reino UnidoFil: Pidgeon, Anna Michle. University of Wisconsin; Estados UnidosFil: Pilia, Oriana. Imperial College London; Reino UnidoFil: Possingham, Hugh P.. Imperial College London; Reino Unido. The University Of Queensland; AustraliaFil: Possingham, Max L.. No especifíca;Fil: Raheem, Dinarzarde C.. Royal Belgian Institute of Natural Sciences; Bélgica. Natural History Museum; Reino UnidoFil: Ribeiro, Danilo B.. Universidade Federal do Mato Grosso do Sul; BrasilFil: Ribeiro Neto, Jose D.. Universidade Federal de Pernambuco; BrasilFil: Robinson, Douglas W.. State University of Oregon; Estados UnidosFil: Robinson, Richard. Manjimup Research Centre; AustraliaFil: Rytwinski, Trina. Carleton University; CanadáFil: Scherber, Christoph. Universität Göttingen; AlemaniaFil: Slade, Eleanor M.. University of Oxford; Reino UnidoFil: Somarriba, Eduardo. Centro Agronómico Tropical de Investigación y Enseñanza; Costa RicaFil: Stouffer, Philip C.. State University of Louisiana; Estados UnidosFil: Struebig, Matthew J.. University of Kent; Reino UnidoFil: Tylianakis, Jason M.. University College London; Estados Unidos. Imperial College London; Reino UnidoFil: Teja, Tscharntke. Universität Göttingen; AlemaniaFil: Tyre, Andrew J.. Universidad de Nebraska - Lincoln; Estados UnidosFil: Urbina Cardona, Jose N.. Pontificia Universidad Javeriana; ColombiaFil: Vasconcelos, Heraldo L.. Universidade Federal de Uberlandia; BrasilFil: Wearn, Oliver. Imperial College London; Reino Unido. The Zoological Society of London; Reino UnidoFil: Wells, Konstans. University of Adelaide; AustraliaFil: Willig, Michael R.. University of Connecticut; Estados UnidosFil: Wood, Eric. University of Wisconsin; Estados UnidosFil: Young, Richard P.. Durrell Wildlife Conservation Trust; Reino UnidoFil: Bradley, Andrew V.. Imperial College London; Reino UnidoFil: Ewers, Robert M.. Imperial College London; Reino Unid
Population Genetics of GYPB and Association Study between GYPB*S/s Polymorphism and Susceptibility to P. falciparum Infection in the Brazilian Amazon
- Author
- A Macgregor
- AA Escalante
- AF Cowman
- AK Bei
- AM Deans
- Andréa R. Rossit
- B Beiguelman
- B Lell
- CA Facer
- CA Facer
- CA Lobo
- CE Cavasini
- CE Cavasini
- CH Huang
- CH Huang
- CV Jennings
- Daiane C. Costa
- Daphne R. T. Amaral
- DC Mayer
- DE Neafsey
- DF Conrad
- DJ Schaid
- DJ Weatherall
- DM Altshuler
- Eduardo Tarazona-Santos
- F Montoya
- F Tajima
- F Tajima
- G Ayodo
- G Hashmi
- G Hashmi
- G Pasvol
- G Pasvol
- G Pasvol
- GA Watterson
- Georges Snounou
- GH Vos
- GR Fraser
- HY Wang
- J Baum
- J Baum
- JBS Haldane
- JC Barrett
- JK Pritchard
- JK Pritchard
- JM Akey
- JN Okoyeh
- JR Storry
- JR Storry
- KT Montgomery
- L Castilho
- LH Miller
- LH Miller
- LH Miller
- Lilian Castilho
- Luciana W. Zuccherato
- M Contreras
- M Kimura
- M Machado
- M Stephens
- Mariano G. Zalis
- Marion E. Reid
- MC Campbell
- MC da Silva
- ME Reid
- ME Reid
- Moara Machado
- N Li
- Natália G. Furlani
- NP Santos
- OO Blumenfeld
- P Michon
- P Unger
- PA Zimmerman
- PB Booth
- PB Booth
- PB Booth
- PC Sabeti
- PD Issitt
- R Carter
- R Omoto
- RB McGhee
- RF Lowe
- Ricardo L. Machado
- RLD Machado
- RM Durbin
- Sara Lustigman
- SH Williamson
- Sidney E. B. Santos
- SJ Allen
- SL Lake
- SP Field
- SR Grossman
- SS Patel
- SS Patel
- SW Serjeantson
- TJ Hadley
- V Ramensky
- W Baleotti Jr
- W Baleotti Jr
- W Dahr
- W Dahr
- WG Hill
- YX Fu
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2011
- Field of study
Merozoites of Plasmodium falciparum invade through several pathways using different RBC receptors. Field isolates appear to use a greater variability of these receptors than laboratory isolates. Brazilian field isolates were shown to mostly utilize glycophorin A-independent invasion pathways via glycophorin B (GPB) and/or other receptors. The Brazilian population exhibits extensive polymorphism in blood group antigens, however, no studies have been done to relate the prevalence of the antigens that function as receptors for P. falciparum and the ability of the parasite to invade. Our study aimed to establish whether variation in the GYPB*S/s alleles influences susceptibility to infection with P. falciparum in the admixed population of Brazil.Two groups of Brazilian Amazonians from Porto Velho were studied: P. falciparum infected individuals (cases); and uninfected individuals who were born and/or have lived in the same endemic region for over ten years, were exposed to infection but have not had malaria over the study period (controls). The GPB Ss phenotype and GYPB*S/s alleles were determined by standard methods. Sixty two Ancestry Informative Markers were genotyped on each individual to estimate admixture and control its potential effect on the association between frequency of GYPB*S and malaria infection.GYPB*S is associated with host susceptibility to infection with P. falciparum; GYPB*S/GYPB*S and GYPB*S/GYPB*s were significantly more prevalent in the in the P. falciparum infected individuals than in the controls (69.87% vs. 49.75%; P<0.02). Moreover, population genetics tests applied on the GYPB exon sequencing data suggest that natural selection shaped the observed pattern of nucleotide diversity.Epidemiological and evolutionary approaches suggest an important role for the GPB receptor in RBC invasion by P. falciparum in Brazilian Amazons. Moreover, an increased susceptibility to infection by this parasite is associated with the GPB S+ variant in this population
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure.
- Author
- Abecasis GR
- Abecasis GR
- Abecasis Goncalo R.
- Absher D
- Absher D
- Aherrahrou Z
- Ahmadi KR
- Alavere Helene
- Alizadeh Behrooz Z.
- Altshuler D
- Altshuler David
- Amin Najaf
- Andersen K
- Andrews JS
- Aragam J
- Arking DE
- Arnett DK
- Arora Pankaj
- Aspelund T
- Aspelund T
- Aspelund Thor
- Assime TL
- Assimes TL
- Assimes TL
- Atkinson EJ
- Attwood T
- Aulchenko YS
- Aulchenko YS
- Aulchenko YS
- Aulchenko Yurii
- Badola S
- Bakker SJ
- Ball SG
- Balmforth AJ
- Bandinelli Stefania
- Barbalic M
- Barroso In S.
- Beckmann J
- Beckmann Jacques S.
- Beilby John P.
- Bekaert S
- Belz S
- Benjamin E
- Benjamin EJ
- Benjamin EJ
- Bergman Richard N.
- Bergmann Sven
- Bickel C
- Bilo HJ
- Bis J
- Bis JC
- Bis JC
- Bis Joshua C
- Blankenberg S
- Blankenberg S
- Blankenberg S
- Blettner M
- Boban M
- Boban Mladen
- Bochud M
- Bochud Murielle
- Boehnke Michael
- Boerwinkle E
- Boerwinkle E
- Boerwinkle E
- Boerwinkle E
- Boerwinkle Eric
- Boomsma Dorret I.
- Borecki I
- Bragg-Gresham Jennifer L.
- Brandstätter A
- Braund P
- Braund PS
- Breteler Monique
- Brown MJ
- Bruse P
- Buckley Brendan
- Burke Gregory L
- Burnett MS
- Burtt N
- Böger CA
- Böhm BO
- Cambien F
- Cambien F
- Campbell H
- Campbell S
- Campbell Harry
- Caulfield MJ
- Caulfield Mark J.
- Cavalieri M
- Chakravarti Aravinda
- Chambers JC
- Chambers John C.
- Chang PP
- Chasman DI
- Chasman Daniel I.
- Chen IY
- Chen L
- Chen L
- Chen Yii-Der Ida
- Clarke Robert
- Cockcroft JR
- Collins Francis S.
- Connell JM
- Cook HT
- Cooper J
- Coresh J
- Cornelia M. McEniery CM
- Cornelis MC
- Corre Tanguy
- Corsi Anna Maria
- Cotlarciuc I
- Couper D
- Crisp-Hihn A
- Cupples L
- Cupples LA
- Cupples LA
- Curhan GC
- D'Adamo Adamo Pio
- Dandona S
- Davey Smith G
- Davies Gail
- de Andrade M
- De Backer GG
- De Bacquer D
- de Boer IH
- De Buyzere ML
- De Geus Eco J. C.
- de Jong PE
- De Meyer T
- de Silva R
- Deary Ian J.
- Debette Stéphanie
- Deckers JW
- Dehghan A
- Dehghan A
- Dehghan A
- Dehghan A
- Dehghan A
- Del Greco M Fabiola
- Deloukas P
- Deloukas P
- Demissie S
- Demissie-Banjaw S
- Deng G
- Destefano Anita L.
- Devaney J
- Devuyst O
- Dikkeschei LD
- Dimkovic N
- Ding J
- Dobnig H
- Dockrell M
- Doering A
- Dominiczak A
- Döring Angela
- Dörr M
- Dörr Marcus
- Eardman J
- Ebrahim S
- Eggermann T
- Ehret Georg B.
- Eiriksdottir G
- Eiriksdottir G
- Ellinghaus D
- Elliott P
- Elliott Paul
- Elosua R
- Emilsson Valur
- Endlich K
- Epstein SE
- Erdmann J
- Erdmann J
- Erdmann J
- Erdmann J
- Erdmann J
- Erdmann J
- Erdmann Jeanette
- Esko Tõnu
- Eyheramendy Susana
- Fabretto Antonella
- Facheris Maurizio
- Faletra Flavio
- Farrall M
- Farrall Martin
- Feitosa M
- Felix JF
- Felix JF
- Felix JF
- Felix SB
- Felix Janine F.
- Ferrucci L
- Ferrucci L
- Ferrucci L
- Ferrucci Luigi
- Fischer M
- Floege J
- Foad N
- Folsom A
- Folsom AR
- Fornage Myriam
- Forouhi NG
- Fortmann S
- Fox CS
- Fox ER
- Franke A
- Friedrich N
- Fu Jingyuan
- Fuchsberger C
- Gabriel SB
- Galan Pilar
- Gale DP
- Ganesh Santhi K.
- Gansevoort RT
- Gao X
- Gasparini Paolo
- Giallauria F
- Gibson Q
- Gider Pierre
- Gieger Christian
- Gillebert TC
- Glazer N
- Glazer NL
- Glazer NL
- Glazer NL
- Glazer Nicole L.
- Go A
- Goel Anuj
- Goodall AH
- Gottdiener JS
- Gottdiener JS
- Gracey J
- Grammer TB
- Gray E
- Greiser KH
- Gretarsdottir S
- Groop Leif
- Grosshennig A
- Grosshennig A
- Gudnason V
- Gudnason V
- Gudnason V
- Gudnason Vilmundur
- Guiducci C
- Gulcher JR
- Gulde S
- Guo Xiuqing
- Gwilliams R
- Gyllensten U
- Gyllensten Ulf B.
- Hadley David
- Haerting J
- Hakonarson HH
- Hall A
- Hall AS
- Haller Toomas
- Halperin E
- Halperin E
- Hamburg NM
- Hamsten Anders
- Han X
- Haritunians T
- Haritunians T
- Haritunians T
- Harris T
- Harris TB
- Harris TB
- Harris Tamara B.
- Hastie N
- Hayward C
- Hayward Caroline
- Heath Simon
- Heckbert S
- Heckbert SR
- Heckbert SR
- Hedblad B
- Heid IM
- Heimerl S
- Hengstenberg C
- Hengstenberg C
- Hengstenberg C
- Hengstenberg C
- Henneman Peter
- Hepkema BG
- Hercberg Serge
- Hernandez Dena
- Hernandez-Fuentes M
- Herrington DM
- Hlatky M
- Hoen Peter A. C. T.
- Hoffmann MM
- Hofman A
- Hofman A
- Hofman A
- Hofman A
- Hofman A
- Hofman Albert
- Holm H
- Holm H
- Holm Hilma
- Homan van der Heide JJ
- Homuth G
- Hopewell Jemma C.
- Hottenga Jouke-Jan
- Howard TD
- Hu FB
- Hung Joseph
- Hwang SJ
- Hwang Shih-Jen
- Hypponen E
- Igl W
- Igl Wilmar
- Illig T
- Illig T
- Imboden M
- Ingelsson E
- Iribarren C
- Isaacs A
- Isaacs A
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- Publication venue
- Nat Genet
- Publication date
- 01/01/2011
- Field of study
Numerous genetic loci have been associated with systolic blood pressure (SBP) and diastolic blood pressure (DBP) in Europeans. We now report genome-wide association studies of pulse pressure (PP) and mean arterial pressure (MAP). In discovery (N = 74,064) and follow-up studies (N = 48,607), we identified at genome-wide significance (P = 2.7 × 10(-8) to P = 2.3 × 10(-13)) four new PP loci (at 4q12 near CHIC2, 7q22.3 near PIK3CG, 8q24.12 in NOV and 11q24.3 near ADAMTS8), two new MAP loci (3p21.31 in MAP4 and 10q25.3 near ADRB1) and one locus associated with both of these traits (2q24.3 near FIGN) that has also recently been associated with SBP in east Asians. For three of the new PP loci, the estimated effect for SBP was opposite of that for DBP, in contrast to the majority of common SBP- and DBP-associated variants, which show concordant effects on both traits. These findings suggest new genetic pathways underlying blood pressure variation, some of which may differentially influence SBP and DBP
Differential cross section measurements for the production of a W boson in association with jets in proton–proton collisions at √s = 7 TeV
- Author
- Abbaneo Duccio
- Abbiendi Giovanni
- Abbrescia Marcello
- Abdullin Salavat
- Abdulsalam Abdulla
- Acosta Darin
- Acosta John Gabriel
- Adair Antony
- Adam Wolfgang
- Adams Mark Raymond
- Adams Todd
- Adiguzel Aytul
- Adler Volker
- Adzic Petar
- Agram Jean-Laurent
- Ahmad Ashfaq
- Ahmad Muhammad
- Ahuja Sudha
- Akchurin Nural
- Akgun Bora
- Akin Ilina Vasileva
- Alagoz Enver
- Albajar Carmen
- Albayrak Elif Asli
- Albergo Sebastiano
- Albrow Michael
- Alcaraz Maestre Juan
- Aldaya Martin Maria
- Alderweireldt Sara
- Aldá Júnior Walter Luiz
- Aleksandrov Aleksandar
- Alexander James
- Alimena Juliette
- Alverson George
- Alves Gilvan
- Amapane Nicola
- Amsler Claude
- Anagnostou Georgios
- Anderson Jacob
- Andrea Jeremy
- Andreev Vladimir
- Andreev Yuri
- Andrews Warren
- Androsov Konstantin
- Antonelli Louis
- Antunovic Zeljko
- Apanasevich Leonard
- Apollinari Giorgio
- Appelt Eric
- Apresyan Artur
- Apyan Aram
- Arcidiacono Roberta
- Arenton Michael Wayne
- Argiro Stefano
- Arneodo Michele
- Arora Sanjay
- Asavapibhop Burin
- Asawatangtrakuldee Chayanit
- Asin Ivan
- Askew Andrew
- Aslanoglou Xenofon
- Assran Yasser
- Ata Metin
- Attikis Alexandros
- Aubin Alexandre
- Auffray Etiennette
- Autermann Christian
- Auzinger Georg
- Avdeeva Ekaterina
- Avery Paul
- Avetisyan Aram
- Avila Carlos
- Azarkin Maksim
- Azhgirey Igor
- Aziz Tariq
- Azzi Patrizia
- Azzolini Virginia
- Azzurri Paolo
- Baarmand Marc M
- Babb John
- Baber Mark
- Bacchetta Nicola
- Bachmair Felix
- Bachtis Michail
- Baden Drew
- Baffioni Stephanie
- Bagliesi Giuseppe
- Bahtiyar Hüseyin
- Baillon Paul
- Bainbridge Robert
- Bakhshiansohi Hamed
- Bakirci Mustafa Numan
- Ball Austin
- Ban Yong
- Banerjee Sudeshna
- Banerjee Sunanda
- Bansal Monika
- Bansal Sunil
- Barbagli Giuseppe
- Barberis Emanuela
- Barbieri Richard
- Barbone Lucia
- Barfuss Anne-Fleur
- Bargassa Pedrame
- Barge Derek
- Baringer Philip
- Barker Anthony
- Barlas Esra
- Barnes Virgil E
- Barnett Bruce Arnold
- Barney David
- Barone Luciano
- Barth Christian
- Bartosik Nazar
- Basegmez Suzan
- Battilana Carlo
- Bauer Gerry
- Bauerdick Lothar AT
- Baumgartel Darin
- Baus Colin
- Bayshev Igor
- Bazterra Victor Eduardo
- Bean Alice
- Beauceron Stephanie
- Beaudette Florian
- Beaupere Nicolas
- Beernaert Kelly
- Behnamian Hadi
- Behr Joerg
- Behrenhoff Wolf
- Behrens Ulf
- Beirão Da Cruz E Silva Cristóvão
- Belforte Stefano
- Beliy Nikita
- Belknap Donald
- Bell Alan James
- Bell Ken W
- Bellan Riccardo
- Bellato Marco
- Beluffi Camille
- Belyaev Alexander
- Belyaev Andrey
- Benaglia Andrea
- Bencze Gyorgy
- Bendavid Joshua
- Benedetti Daniele
- Benelli Gabriele
- Benhabib Lamia
- Beni Noemi
- Benitez Jose F
- Benucci Leonardo
- Benussi Luigi
- Benvenuti Alberto
- Beranek Sarah
- Beretvas Andrew
- Bergauer Thomas
- Berger Joram
- Bergholz Matthias
- Beri Suman Bala
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- Bernardini Jacopo
- Bernet Colin
- Berry Douglas
- Berry Edmund
- Berryhill Jeffrey
- Bertl Willi
- Besancon Marc
- Betchart Burton
- Bethani Agni
- Betts Russell Richard
- Bhardwaj Ashutosh
- Bhat Pushpalatha C
- Bhatnagar Vipin
- Bhattacharya Saptaparna
- Bhattacharya Satyaki
- Bialkowska Helena
- Bian Jian-Guo
- Bianchi Giovanni
- Bianchini Lorenzo
- Bianco Stefano
- Biasini Maurizio
- Biino Cristina
- Bilei Gian Mario
- Bilin Bugra
- Bilki Burak
- Bilmis Selcuk
- Bisello Dario
- Bitioukov Sergei
- Blekman Freya
- Blobel Volker
- Bloch Daniel
- Bloch Philippe
- Bloom Kenneth
- Bluj Michal
- Blumenfeld Barry
- Blyweert Stijn
- Boccali Tommaso
- Bocci Andrea
- Bochenek Joseph
- Bodek Arie
- Bodlak Martin
- Boimska Bożena
- Bolla Gino
- Bolognesi Sara
- Bonacorsi Daniele
- Bonato Alessio
- Bondu Olivier
- Bontenackels Michael
- Boos Edouard
- Bornheim Adolf
- Borras Kerstin
- Bortignon Pierluigi
- Bortoletto Daniela
- Bose Suvadeep
- Bose Tulika
- Botta Cristina
- Boudoul Gaelle
- Bouhali Othmane
- Bourilkov Dimitri
- Boutle Sarah
- Bradmiller-Feld John
- Braibant-Giacomelli Sylvie
- Branca Antonio
- Branson James G
- Breedon Richard
- Breto Guillermo
- Breuker Horst
- Brew Christopher
- Brigliadori Luca
- Brigljevic Vuko
- Brinkerhoff Andrew
- Brinson Jessica
- Broccolo Giuseppe
- Brochero Cifuentes Javier Andres
- Brochet Sébastien
- Brom Jean-Marie
- Brona Grzegorz
- Brooke James John
- Brown Robert M
- Brownson Eric
- Brun Hugues
- Bruner Christopher
- Bruno Giacomo
- Buchmann Marco-Andrea
- Buchmuller Oliver
- Bucinskaite Inga
- Bunkowski Karol
- Bunn Julian
- Buontempo Salvatore
- Burgmeier Armin
- Burkett Kevin
- Burton Darren
- Busson Philippe
- Busza Wit
- Butler Joel Nathan
- Butler Philip H
- Butz Erik
- Bylsma Ben
- Bäni Lukas
- Böser Christian
- Cabrillo Iban Jose
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- Chabert Eric Christian
- Chakaberia Irakli
- Chamizo Llatas Maria
- Chan Kwok Ming
- Chan Matthew
- Chang Paoti
- Chang Sunghyun
- Chang You-Hao
- Chang Yu-Wei
- Chanon Nicolas
- Chao Yuan
- Chaparro Sierra Luisa Fernanda
- Charaf Otman
- Charlot Claude
- Chasco Matthew
- Chasserat Julien
- Chatterjee Avishek
- Chatterjee Kalyanmoy
- Chatterjee Rajdeep Mohan
- Chauhan Sushil
- Checchia Paolo
- Chen Guo-Ming
- Chen He-Sheng
- Chen Kai-Feng
- Chen Kuan-Hsin
- Chen Mingshui
- Chen Po-Hsun
- Chen Yi
- Cheng Tongguang
- Cherepanov Vladimir
- Chertok Maxwell
- Cheung Harry
- Chhibra Simranjit Singh
- Chierici Roberto
- Chinellato Jose
- Chiochia Vincenzo
- Chiorboli Massimiliano
- Chlebana Frank
- Choi Minkyoo
- Choi Suyong
- Choi Young Kyu
- Choi Young-Il
- Chou John Paul
- Choudhary Brajesh C
- Choudhury Somnath
- Christopher Grant
- Chu Jennifer
- Chwalek Thorsten
- Ciangottini Diego
- Ciesielski Robert
- Cihangir Selcuk
- Cimmino Anna
- Ciocci Maria Agnese
- Cittolin Sergio
- Ciulli Vitaliano
- Civinini Carlo
- Claes Daniel R
- Clare Robert
- Clarida Warren
- Clement Emyr
- Clerbaux Barbara
- CMS Collaboration
- Cockerill David JA
- Codispoti Giuseppe
- Colafranceschi Stefano
- Colaleo Anna
- Cole Joanne
- Colino Nicanor
- Collard Caroline
- Colling David
- Contardo Didier
- Conte Eric
- Contreras-Campana Christian
- Contreras-Campana Emmanuel
- Conway John
- Conway Rylan
- Cooper Seth
- Cornelis Tom
- Correa Martins Junior Marcos
- Cossutti Fabio
- Costa Marco
- Costa Salvatore
- Costantini Silvia
- Costanza Francesco
- Couderc Fabrice
- Coughlan John A
- Cousins Robert
- Covarelli Roberto
- Cowden Christopher
- Cox Bradley
- Cox Peter Timothy
- Creanza Donato
- Cripps Nicholas
- Crucy Shannon
- Cuevas Javier
- Cuffiani Marco
- Cumalat John Perry
- Curry David
- Cussans David
- Custódio Analu
- Cutajar Michael
- Cutts David
- Cwiok Mikolaj
- Czellar Sandor
- D'Agnolo Raffaele Tito
- D'Alessandro Raffaello
- D'Alfonso Mariarosaria
- D'Enterria David
- D'Hondt Jorgen
- Da Costa Eliza Melo
- Da Silveira Gustavo Gil
- Dabrowski Anne
- Daci Nadir
- Dahmes Bryan
- Dahms Torsten
- Dalchenko Mykhailo
- Dall'Osso Martino
- Dallavalle Gaetano-Marco
- Damgov Jordan
- Danielson Thomas
- Das Souvik
- Daskalakis Georgios
- Dasu Sridhara
- Daubie Evelyne
- Dauncey Paul
- David Tinoco Mendes Andre
- Davies Gavin
- De Almeida Dias Flavia
- de Barbaro Pawel
- De Benedetti Abraham
- De Boer Wim
- De Cosa Annapaola
- De Filippis Nicola
- De Gruttola Michele
- De Guio Federico
- De Jesus Damiao Dilson
- De La Cruz Begona
- De La Cruz-Burelo Eduard
- De Lentdecker Gilles
- De Mattia Marco
- De Moraes Gregores Eduardo
- De Oliveira Martins Carley
- De Palma Mauro
- De Roeck Albert
- de Trocóniz Jorge F
- De Visscher Simon
- De Wolf Eddi A
- Degano Alessandro
- Deisher Amanda
- Deiters Konrad
- Dejardin Marc
- Del Re Daniele
- Delaere Christophe
- Delannoy Andrés G
- Delgado Peris Antonio
- Dell'Orso Roberto
- Della Negra Michel
- Della Ricca Giuseppe
- Demaria Natale
- Demina Regina
- Demiragli Zeynep
- Demortier Luc
- Denegri Daniel
- Depasse Pierre
- Dermenev Alexander
- Descroix Alexis
- Dewanjee Ram Krishna
- Dhingra Nitish
- Di Giovanni Gian Piero
- Di Guida Salvatore
- Di Marco Emanuele
- Di Matteo Leonardo
- Diamond Brendan
- Diemoz Marcella
- Dierlamm Alexander
- Dietz Charles
- Dietz-Laursonn Erik
- Diez Pardos Carmen
- Dildick Sven
- Dilsiz Kamuran
- Dimitrov Anton
- Dinardo Mauro Emanuele
- Dishaw Adam
- Dissertori Günther
- Dittmann Jay
- Dittmar Michael
- Dittmer Susan
- Dobrzynski Ludwik
- Dobson Marc
- Dobur Didar
- Dolen James
- Dominguez Aaron
- Dominik Wojciech
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- Smirnov Vitaly
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- Smith James
- Smith John
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- Wang Dayong
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- Wang Jian
- Wang Quan
- Wang Xianyou
- Wang Zheng
- Wardle Nicholas
- Wayand Stefan
- Wayne Mitchell
- Weber Hannsjoerg Artur
- Weber Hendrik
- Weber Martin
- Weber Matthias
- Weiler Thomas
- Weinberg Marc
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- Wendland Lauri
- Weng Yao
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- West Christopher
- Wetzel James
- Whitbeck Andrew
- Whitmore Juliana
- Wickramage Nadeesha
- Wilbur Scott
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- Wilkinson Richard
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- Winer Brian L
- Winn Dave
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- Wood John
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- Worm Steven
- Wright Douglas
- Wulsin Howard Wells
- Wulz Claudia-Elisabeth
- Wyslouch Bolek
- Wöhri Hermine Katharina
- Würthwein Frank
- Xiao Hong
- Xie Si
- Xie Wei
- Xu Lingshan
- Yagil Avraham
- Yalvac Metin
- Yang Fan
- Yang Mingming
- Yang Yong
- Yazgan Efe
- Yelton John
- Yetkin Taylan
- Yi Kai
- Yilmaz Yetkin
- Yohay Rachel
- Yoo Hwi Dong
- Yoo Jaehyeok
- York Andrew
- Yu Intae
- Yu Shin-Shan
- Yumiceva Francisco
- Yücel Mete
- Zabel James
- Zabi Alexandre
- Zablocki Jakub
- Zaganidis Nicolas
- Zakaria Mohammed
- Zalewski Piotr
- Zanetti Anna
- Zanetti Marco
- Zarubin Anatoli
- Zeinali Maryam
- Zenz Seth Conrad
- Zeuner Wolfram Dietrich
- Zeyrek Mehmet
- Zhang Jinzhong
- Zhang Linlin
- Zheng Yu
- Zhokin Alexander
- Zhu Ren-Yuan
- Zhukov Valery
- Zhukova Victoria
- Zito Giuseppe
- Zou Wei
- Zsigmond Anna Julia
- Zucchetta Alberto
- Zumerle Gianni
- Zuranski Andrzej
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2014
- Field of study
Measurements are reported of differential cross sections for the production of a W boson, which decays into a muon and a neutrino, in association with jets, as a function of several variables, including the transverse momenta (pT) and pseudorapidities of the four leading jets, the scalar sum of jet transverse momenta (HT), and the difference in azimuthal angle between the directions of each jet and the muon. The data sample of pp collisions at a centre-of-mass energy of 7 TeV was collected with the CMS detector at the LHC and corresponds to an integrated luminosity of 5.0 fb[superscript −1]. The measured cross sections are compared to predictions from Monte Carlo generators, MadGraph + pythia and sherpa, and to next-to-leading-order calculations from BlackHat + sherpa. The differential cross sections are found to be in agreement with the predictions, apart from the pT distributions of the leading jets at high pT values, the distributions of the HT at high-HT and low jet multiplicity, and the distribution of the difference in azimuthal angle between the leading jet and the muon at low values.United States. Dept. of EnergyNational Science Foundation (U.S.)Alfred P. Sloan Foundatio
Optimasi Portofolio Resiko Menggunakan Model Markowitz MVO Dikaitkan dengan Keterbatasan Manusia dalam Memprediksi Masa Depan dalam Perspektif Al-Qur`an
- Author
- Aarrestad Thea Klaeboe
- Abbaneo Duccio
- Abbiendi Giovanni
- Abbrescia Marcello
- Abdullin Salavat
- Abdulsalam Abdulla
- Abercrombie Daniel
- Abu Zeid Shimaa
- Ackert Andrew
- Acosta Darin
- Acosta John Gabriel
- Adair Antony
- Adam Wolfgang
- Adams Jordon Rowe
- Adams Mark Raymond
- Adams Todd
- Adzic Petar
- Agapitos Antonis
- Aggleton Robin
- Agram Jean-Laurent
- Ahmad Ashfaq
- Ahmad Muhammad
- Ahmad Muhammad
- Ahmed Ijaz
- Ahuja Sudha
- Akchurin Nural
- Akgun Bora
- Al-bataineh Ayman
- Albergo Sebastiano
- Albert Andreas
- Albrow Michael
- Alcaraz Maestre Juan
- Aldaya Martin Maria
- Alderweireldt Sara
- Aldá Júnior Walter Luiz
- Aleksandrov Aleksandar
- Alexakhin Vadim
- Alexander James
- Alimena Juliette
- Allen Brandon
- Almond John
- Alunni Solestizi Luisa
- Alverson George
- Alves Fábio Lúcio
- Alves Gilvan
- Alyari Maral
- Amapane Nicola
- Amsler Claude
- Anagnostou Georgios
- Anderson Dustin
- Anderson Ian
- Andrea Jeremy
- Andreev Vladimir
- Andreev Yuri
- Andrews Michael Benjamin
- Androsov Konstantin
- Anelli Christopher
- Antonelli Louis
- Antropov Iurii
- Antunovic Zeljko
- Apanasevich Leonard
- Apollinari Giorgio
- Apresyan Artur
- Apyan Aram
- Arcaro Daniel
- Arcidiacono Roberta
- Arenton Michael Wayne
- Argiro Stefano
- Arneodo Michele
- Asavapibhop Burin
- Asawatangtrakuldee Chayanit
- Askew Andrew
- Attikis Alexandros
- Aubin Alexandre
- Auffray Etiennette
- Autermann Christian
- Auzinger Georg
- Avdeeva Ekaterina
- Avery Paul
- Avetisyan Aram
- Avila Carlos
- Azarkin Maksim
- Azhgirey Igor
- Aziz Tariq
- Azzi Patrizia
- Azzolini Virginia
- Azzurri Paolo
- Aşılar Ece
- Baarmand Marc M
- Baber Mark
- Bacchetta Nicola
- Bachmair Felix
- Bachtis Michail
- Baden Drew
- Baffioni Stephanie
- Bagliesi Giuseppe
- Bahinipati Seema
- Baillon Paul
- Bainbridge Robert
- Bakhshiansohi Hamed
- Ball Austin
- Ball Fionn
- Ban Yong
- Banerjee Sudeshna
- Banerjee Sunanda
- Bansal Sunil
- Barbagli Giuseppe
- Barberis Emanuela
- Barbieri Richard
- Bargassa Pedrame
- Baringer Philip
- Barker Anthony
- Barnes Virgil E
- Barney David
- Baron Owen
- Barone Luciano
- Barria Patrizia
- Barrio Luna Mar
- Bartek Rachel
- Barth Christian
- Bartosik Nazar
- Bartók Márton
- Baskakov Alexey
- Battilana Carlo
- Baty Austin
- Bauerdick Lothar AT
- Baumgartel Darin
- Baus Colin
- Bayshev Igor
- Bean Alice
- Beauceron Stephanie
- Beaudette Florian
- Beck Lana
- Beernaert Kelly
- Behera Prafulla Kumar
- Behnamian Hadi
- Behnke Olaf
- Behrens Ulf
- Bein Samuel
- Beirão Da Cruz E Silva Cristóvão
- Belchior Batista Das Chagas Ewerton
- Belforte Stefano
- Beliy Nikita
- Belknap Donald
- Bell Ken W
- Bellan Riccardo
- Belloni Alberto
- Beluffi Camille
- Belyaev Alexander
- Belyaev Andrey
- Benato Lisa
- Bencze Gyorgy
- Bendavid Joshua
- Benelli Gabriele
- Beni Noemi
- Benussi Luigi
- Benvenuti Alberto
- Beranek Sarah
- Beretvas Andrew
- Bergauer Thomas
- Berger Joram
- Beri Suman Bala
- Bernardes Cesar Augusto
- Bernardini Jacopo
- Bernet Colin
- Berry Douglas
- Berry Edmund
- Berryhill Jeffrey
- Bertl Willi
- Besancon Marc
- Betchart Burton
- Betts Russell Richard
- Bhandari Rohan
- Bhardwaj Ashutosh
- Bhat Pushpalatha C
- Bhatnagar Vipin
- Bhattacharya Rajarshi
- Bhattacharya Saptaparna
- Bhattacharya Satyaki
- Bhawandeep Bhawandeep
- Bhopatkar Vallary
- Bhowmik Sandeep
- Bi Ran
- Bialkowska Helena
- Bian Jian-Guo
- Bianchini Lorenzo
- Bianco Stefano
- Bierwagen Katharina
- Biino Cristina
- Bilei Gian Mario
- Bilin Bugra
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- Bin Anuar Afiq Aizuddin
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- Boccali Tommaso
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- Boletti Alessio
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- Bonacorsi Daniele
- Bonato Alessio
- Bondu Olivier
- Boos Edouard
- Boren Samuel
- Bornheim Adolf
- Borras Kerstin
- Bortignon Pierluigi
- Borzou Ahmad
- Bose Tulika
- Botta Cristina
- Boudoul Gaelle
- Bouhali Othmane
- Bourilkov Dimitri
- Bouvier Elvire
- Bowen James
- Bradmiller-Feld John
- Braghieri Alessandro
- Braibant-Giacomelli Sylvie
- Brandstetter Johannes
- Brandt Stephanie
- Branson James G
- Breedon Richard
- Breto Guillermo
- Brew Christopher
- Brianza Luca
- Brigliadori Luca
- Brigljevic Vuko
- Brinkerhoff Andrew
- Brinson Jessica
- Brito Lucas
- Brochero Cifuentes Javier Andres
- Brochet Sébastien
- Brodski Michael
- Brom Jean-Marie
- Brondolin Erica
- Brooke James John
- Brown Robert M
- Brun Hugues
- Bruner Christopher
- Bruno Giacomo
- Buchmuller Oliver
- Bucinskaite Inga
- Bundock Aaron
- Bunkowski Karol
- Bunn Julian
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- Burkett Kevin
- Burns Douglas
- Burns Dustin
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- Busson Philippe
- Busza Wit
- Butler Joel Nathan
- Butler Philip H
- Buttignol Michael
- Butz Erik
- Bylinkin Alexander
- Bylsma Ben
- Byszuk Adrian
- Bäni Lukas
- Cabrera Andrés
- Cabrillo Iban Jose
- Cadamuro Luca
- Caillol Cécile
- Cakir Altan
- Calabria Cesare
- Calderon De La Barca Sanchez Manuel
- Calderon Alicia
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- Call Kenneth
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- Campbell Alan
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- Carpinteyro Severiano
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- Carrillo Montoya Camilo Andres
- Carrillo Moreno Salvador
- Cartiglia Nicolo
- Carvalho Antunes De Oliveira Alexandra
- Carvalho Wagner
- Carver Matthew
- Casal Bruno
- Casarsa Massimo
- Casasso Stefano
- Castaldi Rino
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- Castilla-Valdez Heriberto
- Castiñeiras De Saa Juan Ramon
- Castle James
- Castro Andrea
- Caudron Adrien
- Cavallari Francesca
- Cavallo Francesca Romana
- Cavallo Nicola
- Cavanaugh Richard
- Celik Ali
- Centis Vignali Matteo
- Cepeda Maria
- Cerati Giuseppe Benedetto
- Cerci Salim
- Cerminara Gianluca
- Cerrada Marcos
- Chabert Eric Christian
- Chadeeva Marina
- Chamizo Llatas Maria
- Chang Paoti
- Chang You-Hao
- Chang Yu-Wei
- Chanon Nicolas
- Chao Yuan
- Chaparro Sierra Luisa Fernanda
- Chapon Emilien
- Charaf Otman
- Charlot Claude
- Chatterjee Kalyanmoy
- Chatterjee Rajdeep Mohan
- Chauhan Shubhanshu
- Chauhan Sushil
- Chaves Jorge
- Chawla Ridhi
- Chen Geng
- Chen Guo-Ming
- Chen He-Sheng
- Chen Kai-Feng
- Chen Mingshui
- Chen Po-Hsun
- Chen Ye
- Chen Yi
- Chen Zhenyu
- Chenarani Shirin
- Cheng Tongguang
- Cherepanov Vladimir
- Chertok Maxwell
- Cheung Harry
- Chhibra Simranjit Singh
- Chierici Roberto
- Chinellato Jose
- Chiorboli Massimiliano
- Chistov Ruslan
- Chlebana Frank
- Cho Sungwoong
- Choi Minkyoo
- Choi Suyong
- Choi Young-Il
- Chou John Paul
- Choudhary Brajesh C
- Choudhury Somnath
- Chtchipounov Leonid
- Chu Jennifer
- Chudasama Ruchi
- Chwalek Thorsten
- Ciangottini Diego
- Cieri Davide
- Cihangir Selcuk
- Cimmino Anna
- Ciocci Maria Agnese
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- Cirkovic Predrag
- Citron Matthew
- Cittolin Sergio
- Ciulli Vitaliano
- Civinini Carlo
- Claes Daniel R
- Clare Robert
- Clarida Warren
- Clarke Christopher
- Clement Emyr
- Clerbaux Barbara
- Cockerill David JA
- Cocoros Alice
- Codispoti Giuseppe
- Colafranceschi Stefano
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- Cole Joanne
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- Colombo Fabio
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- Contardo Didier
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- Cooperstein Stephane
- Cornelis Tom
- Corpe Louie
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- Costa Marco
- Costa Salvatore
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- Coubez Xavier
- Couderc Fabrice
- Coughlan John A
- Courbon Benoit
- Cousins Robert
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- Cowden Christopher
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- Cox Peter Timothy
- Creanza Donato
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- Cumalat John Perry
- Curras Esteban
- Curry David
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- Custódio Analu
- Cutts David
- Czellar Sandor
- D'Alessandro Raffaello
- D'Alfonso Mariarosaria
- D'Enterria David
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- Yazgan Efe
- Yelton John
- Yetkin Elif Asli
- Yetkin Taylan
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- Yilmaz Yetkin
- Yohay Rachel
- Yonamine Ryo
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- You Can
- Yu Geum Bong
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- Yu Shin-Shan
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- Yusli Mohd Nizam
- Zabel James
- Zabi Alexandre
- Zaganidis Nicolas
- Zagoździńska Agnieszka
- Zakaria Mohammed
- Zalewski Piotr
- Zanetti Anna
- Zanetti Marco
- Zarubin Anatoli
- Zeinali Maryam
- Zenoni Florian
- Zenz Seth Conrad
- Zeuner Wolfram Dietrich
- Zevi Della Porta Giovanni
- Zeyrek Mehmet
- Zghiche Amina
- Zhang Fengwangdong
- Zhang Huaqiao
- Zhang Jingyu
- Zhao Jingzhou
- Zhokin Alexander
- Zhu Ren-Yuan
- Zhukov Valery
- Zhukova Victoria
- Zientek Margaret
- Zolkapli Zukhaimira
- Zorbakir Ibrahim Soner
- Zorbilmez Caglar
- Zotto Pierluigi
- Zou David
- Zsigmond Anna Julia
- Zucchetta Alberto
- Zumerle Gianni
- Zuranski Andrzej
- Publication venue
- Sunan Kalijaga State Islamic University
- Publication date
- 01/01/2012
- Field of study
Risk portfolio on modern finance has become increasingly technical, requiring the use of sophisticated mathematical tools in both research and practice. Since companies cannot insure themselves completely against risk, as human incompetence in predicting the future precisely that written in Al-Quran surah Luqman verse 34, they have to manage it to yield an optimal portfolio. The objective here is to minimize the variance among all portfolios, or alternatively, to maximize expected return among all portfolios that has at least a certain expected return. Furthermore, this study focuses on optimizing risk portfolio so called Markowitz MVO (Mean-Variance Optimization). Some theoretical frameworks for analysis are arithmetic mean, geometric mean, variance, covariance, linear programming, and quadratic programming. Moreover, finding a minimum variance portfolio produces a convex quadratic programming, that is minimizing the objective function ðð¥with constraintsð ð 𥠥 ðandð´ð¥ = ð. The outcome of this research is the solution of optimal risk portofolio in some investments that could be finished smoothly using MATLAB R2007b software together with its graphic analysis
Juxtaposing BTE and ATE – on the role of the European insurance industry in funding civil litigation
- Author
- Abbaneo Duccio
- Abbiendi Giovanni
- Abbrescia Marcello
- Abdelalim Ahmed Ali
- Abdullin Salavat
- Abdulsalam Abdulla
- Acosta Darin
- Acosta John Gabriel
- Adair Antony
- Adam Wolfgang
- Adams Mark Raymond
- Adams Todd
- Adiguzel Aytul
- Adler Volker
- Adzic Petar
- Agram Jean-Laurent
- Aguilar-Benitez Manuel
- Ahmad Muhammad
- Ahuja Sudha
- Akchurin Nural
- Akgun Bora
- Akgun Ugur
- Akin Ilina Vasileva
- Alagoz Enver
- Albajar Carmen
- Albayrak Elif Asli
- Albergo Sebastiano
- Albrow Michael
- Alcaraz Maestre Juan
- Aldaya Martin Maria
- Alderweireldt Sara
- Aldá Júnior Walter Luiz
- Alexander James
- Aliev Takhmasib
- Alimena Juliette
- Almeida Nuno
- Alverson George
- Alves Gilvan
- Amapane Nicola
- Amsler Claude
- Anagnostou Georgios
- Anastassov Anton
- Anderson Jacob
- Andrea Jeremy
- Andreev Valeri
- Andreev Vladimir
- Andreev Yuri
- Andrews Warren
- Androsov Konstantin
- Antonelli Louis
- Antunovic Zeljko
- Apanasevich Leonard
- Apollinari Giorgio
- Appelt Eric
- Apresyan Artur
- Apyan Aram
- Arcidiacono Roberta
- Arenton Michael Wayne
- Arfaei Hessamaddin
- Argiro Stefano
- Arneodo Michele
- Arora Sanjay
- Asavapibhop Burin
- Asawatangtrakuldee Chayanit
- Asghar Muhammad Irfan
- Asin Ivan
- Askew Andrew
- Aslanoglou Xenofon
- Assran Yasser
- Ata Metin
- Attikis Alexandros
- Auffray Etiennette
- Autermann Christian Tobias
- Auzinger Georg
- Avdeeva Ekaterina
- Avery Paul
- Avetisyan Aram
- Avila Carlos
- Azarkin Maksim
- Azhgirey Igor
- Aziz Tariq
- Azzi Patrizia
- Azzolini Virginia
- Azzurri Paolo
- Baarmand Marc M.
- Babb John
- Bacchetta Nicola
- Bachmair Felix
- Bachtis Michail
- Baden Drew
- Baffioni Stephanie
- Bagliesi Giuseppe
- Bahtiyar Hüseyin
- Baillon Paul
- Bainbridge Robert
- Bakhshiansohi Hamed
- Bakirci Mustafa Numan
- Ball Austin
- Ban Yong
- Banerjee Sudeshna
- Banerjee Sunanda
- Bansal Monika
- Bansal Sunil
- Barbagli Giuseppe
- Barberis Emanuela
- Barbone Lucia
- Barfuss Anne-Fleur
- Bargassa Pedrame
- Barge Derek
- Baringer Philip
- Barker Anthony
- Barlas Esra
- Barnett Bruce Arnold
- Barney David
- Barone Luciano
- Bartalini Paolo
- Barth Christian
- Bartosik Nazar
- Basegmez Suzan
- Battilana Carlo
- Bauer Gerry
- Bauerdick Lothar A. T.
- Baumgartel Darin
- Baus Colin
- Bayshev Igor
- Bazterra Victor Eduardo
- Bean Alice
- Beauceron Stephanie
- Beaudette Florian
- Beaupere Nicolas
- Beernaert Kelly
- Behr Joerg
- Behrenhoff Wolf
- Behrens Ulf
- Beirão Da Cruz E Silva Cristóvão
- Belforte Stefano
- Beliy Nikita
- Belknap Donald
- Bell Alan James
- Bell Ken W.
- Bellan Riccardo
- Beluffi Camille
- Belyaev Alexander
- Belyaev Andrey
- Benaglia Andrea
- Bencze Gyorgy
- Bendavid Joshua
- Benedetti Daniele
- Benelli Gabriele
- Benhabib Lamia
- Beni Noemi
- Benitez Jose F.
- Benucci Leonardo
- Benussi Luigi
- Benvenuti Alberto
- Beranek Sarah
- Beretvas Andrew
- Bergauer Thomas
- Berger Joram
- Bergholz Matthias
- Beri Suman Bala
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- Bernardini Jacopo
- Bernet Colin
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- Berry Edmund
- Berryhill Jeffrey
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- Besancon Marc
- Betchart Burton
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- Betts Russell Richard
- Bhardwaj Ashutosh
- Bhat Pushpalatha C.
- Bhatnagar Vipin
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- Bhattacharya Satyaki
- Bhatti Anwar
- Bialkowska Helena
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- Bloch Philippe
- Bloom Kenneth
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- Bornheim Adolf
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- Borrello Laura
- Bortignon Pierluigi
- Bortoletto Daniela
- Bose Suvadeep
- Bose Tulika
- Botta Cristina
- Boudoul Gaelle
- Bouhali Othmane
- Bourilkov Dimitri
- Boutle Sarah
- Braibant-Giacomelli Sylvie
- Branca Antonio
- Branson James G.
- Breedon Richard
- Breto Guillermo
- Breuker Horst
- Brew Christopher
- Brigliadori Luca
- Brigljevic Vuko
- Brinkerhoff Andrew
- Broccolo Giuseppe
- Brochero Cifuentes Javier Andres
- Brochet Sébastien
- Brom Jean-Marie
- Brona Grzegorz
- Brooke James John
- Brown Robert M.
- Brownson Eric
- Brun Hugues
- Bruno Giacomo
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- Yetkin Taylan
- Yi Kai
- Yilmaz Yetkin
- Yohay Rachel
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- Yoo Jaehyeok
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- Yumiceva Francisco
- Yun Jae Chul
- Yücel Mete
- Zabel James
- Zabi Alexandre
- Zablocki Jakub
- Zaganidis Nicolas
- Zakaria Mohammed
- Zalewski Piotr
- Zanetti Anna
- Zanetti Marco
- Zarubin Anatoli
- Zeinali Maryam
- Zeise Manuel
- Zenz Seth Conrad
- Zeuner Wolfram Dietrich
- Zeyrek Mehmet
- Zhang Jinzhong
- Zhang Linlin
- Zheng Yu
- Zhokin Alexander
- Zhu Ren-Yuan
- Zhukov Valery
- Zhukova Victoria
- Zielinski Marek
- Zito Giuseppe
- Zotto Pierluigi
- Zou Wei
- Zsigmond Anna Julia
- Zucchetta Alberto
- Zumerle Gianni
- Zuranski Andrzej
- Publication venue
- Publication date
- 01/01/2010
- Field of study
One of the ways in which legal services are financed, and indeed shaped, is through private insurance arrangement. Two contrasting types of legal expenses insurance contracts (LEI) seem to dominate in Europe: before the event (BTE) and after the event (ATE) legal expenses insurance. Notwithstanding institutional differences between different legal systems, BTE and ATE insurance arrangements may be instrumental if government policy is geared towards strengthening a market-oriented system of financing access to justice for individuals and business. At the same time, emphasizing the role of a private industry as a keeper of the gates to justice raises issues of accountability and transparency, not readily reconcilable with demands of competition. Moreover, multiple actors (clients, lawyers, courts, insurers) are involved, causing behavioural dynamics which are not easily predicted or influenced.
Against this background, this paper looks into BTE and ATE arrangements by analysing the particularities of BTE and ATE arrangements currently available in some European jurisdictions and by painting a picture of their respective markets and legal contexts. This allows for some reflection on the performance of BTE and ATE providers as both financiers and keepers. Two issues emerge from the analysis that are worthy of some further reflection. Firstly, there is the problematic long-term sustainability of some ATE products. Secondly, the challenges faced by policymakers that would like to nudge consumers into voluntarily taking out BTE LEI
Penilaian Kinerja Keuangan Koperasi di Kabupaten Pelalawan
- Author
- Abbaneo Duccio
- Abbiendi Giovanni
- Abbrescia Marcello
- Abdelalim Ahmed Ali
- Abdullin Salavat
- Abdulsalam Abdulla
- Acosta Darin
- Acosta John Gabriel
- Adair Antony
- Adam Wolfgang
- Adams Mark Raymond
- Adams Todd
- Adiguzel Aytul
- Adler Volker
- Adzic Petar
- Afanasiev Serguei
- Agram Jean-Laurent
- Aguilar-Benitez Manuel
- Ahmad Muhammad
- Ahuja Sudha
- Akchurin Nural
- Akgun Bora
- Akgun Ugur
- Akin Ilina Vasileva
- Alagoz Enver
- Albajar Carmen
- Albayrak Elif Asli
- Albergo Sebastiano
- Albrow Michael
- Alcaraz Maestre Juan
- Aldaya Martin Maria
- Alderweireldt Sara
- Aldá Júnior Walter Luiz
- Alexander James
- Aliev Takhmasib
- Alimena Juliette
- Almeida Nuno
- Alverson George
- Alves Gilvan
- Amapane Nicola
- Amsler Claude
- Anagnostou Georgios
- Anastassov Anton
- Anderson Jacob
- Andrea Jeremy
- Andreev Valeri
- Andreev Vladimir
- Andreev Yuri
- Andrews Warren
- Androsov Konstantin
- Antonelli Louis
- Antunovic Zeljko
- Apanasevich Leonard
- Apollinari Giorgio
- Appelt Eric
- Apresyan Artur
- Apyan Aram
- Arcidiacono Roberta
- Arenton Michael Wayne
- Arfaei Hessamaddin
- Argiro Stefano
- Arneodo Michele
- Arora Sanjay
- Asavapibhop Burin
- Asawatangtrakuldee Chayanit
- Asghar Muhammad Irfan
- Asin Ivan
- Askew Andrew
- Aslanoglou Xenofon
- Assran Yasser
- Ata Metin
- Attikis Alexandros
- Auffray Etiennette
- Autermann Christian Tobias
- Auzinger Georg
- Avdeeva Ekaterina
- Avery Paul
- Avetisyan Aram
- Avila Carlos
- Azarkin Maksim
- Azhgirey Igor
- Aziz Tariq
- Azzi Patrizia
- Azzolini Virginia
- Azzurri Paolo
- Baarmand Marc M.
- Babb John
- Bacchetta Nicola
- Bachmair Felix
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- Yu Intae
- Yu Shin-Shan
- Yumiceva Francisco
- Yun Jae Chul
- Yücel Mete
- Zabel James
- Zabi Alexandre
- Zablocki Jakub
- Zaganidis Nicolas
- Zakaria Mohammed
- Zalewski Piotr
- Zanetti Anna
- Zanetti Marco
- Zarubin Anatoli
- Zeinali Maryam
- Zeise Manuel
- Zenz Seth Conrad
- Zeuner Wolfram Dietrich
- Zeyrek Mehmet
- Zhang Jinzhong
- Zhang Linlin
- Zheng Yu
- Zhokin Alexander
- Zhu Ren-Yuan
- Zhukov Valery
- Zhukova Victoria
- Zielinski Marek
- Zito Giuseppe
- Zotto Pierluigi
- Zou Wei
- Zsigmond Anna Julia
- Zucchetta Alberto
- Zumerle Gianni
- Zuranski Andrzej
- Publication venue
- Riau University
- Publication date
- 01/01/2009
- Field of study
This paper describe development and financial performance of cooperative in District Pelalawan among 2007 - 2008. Studies on primary and secondary cooperative in 12 sub-districts. Method in this stady use performance measuring of productivity, efficiency, growth, liquidity, and solvability of cooperative. Productivity of cooperative in Pelalawan was highly but efficiency still low. Profit and income were highly, even liquidity of cooperative very high, and solvability was good
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