134 research outputs found
Height and timing of growth spurt during puberty in young people living with vertically acquired HIV in Europe and Thailand.
- Author
- Abou-Rayyah ACM
- Aebi-Popp K
- Akarathum N
- Alfayate S
- Alvarez C
- Alvarez S
- An PK
- Anagnostopoulos A
- Ananpatharachai P
- Angel Roa M
- Angeles Munoz M
- Angulo R
- Anguvaa L
- Antoinette Frick M
- Antonio Couceiro J
- Apilanez M
- Asner S
- Attavinijtrakarn P
- Back NKT
- Badillo K
- Badolato R
- Bakker Y
- Baldi F
- Ball C
- Bamford A
- Bandi S
- Battegay M
- Baumann M
- Beceiro J
- Belfrage E
- Benson C
- Bergsma D
- Berkhout B
- Bernardi S
- Bernasconi E
- Bernatoniene J
- Bezemer DO
- Bezemer M
- Blake E
- Blazquez D
- Boni J
- Bont LJ
- Boucher CAB
- Braun DL
- Breton R
- Bridgwood A
- Bruzzese E
- Bucher HC
- Bunjongpak S
- Bustillo M
- Butler K
- Butler K
- Calavia O
- Callaghan A
- Calmy A
- Cavassini M
- Cellini M
- Chailoet S
- Christie S
- Ciuffi A
- Clapson M
- Clarke DRL
- Cliffe L
- Clough S
- Colino E
- Coll M
- Collado P
- Collins IJ
- Collins IJ
- Consolini R
- Conway S
- Cook C
- Cornelissen MTE
- Coupland U
- Crichton S
- Cristiano L
- Daniels J
- Dapena M
- De Boer CG
- De Groot L
- De Groot-de Jonge H
- De Jong A
- De Martino M
- De Miguel E
- De Tejada BM
- De Tejada MB
- Decker L
- Delforge M
- Di Biagio A
- Dobson D
- Dodi I
- Doerholt K
- Doerholt K
- Doherty C
- Dollenmaier G
- Dona D
- Doroba M
- Dowie M
- Duenas J
- Duncan K
- Duppenthaler A
- Egger M
- Eisenhut M
- El Berkaoui A
- Elzi L
- Ene L
- Erba P
- Escosa L
- Esposito S
- Evans J
- Fairbrother K
- Falcon L
- Faldella G
- Faust SN
- Fehr J
- Fellay J
- Fernandez Mc Phee C
- Fidler K
- Flood T
- Flynn J
- Fortuny C
- Foster C
- Fraaij PLA
- Francini K
- Francis K
- Freeman A
- Freeman H
- Furrer H
- Fux CA
- Gabiano C
- Galli L
- Gamell A
- Garazzino S
- Garcia Hortelano M
- Garcia L
- Garrote E
- Garzon M
- Gavilan C
- Geelen SPM
- Geerlinks J
- Genovese O
- Giacomet V
- Giaquinto C
- Gibb DM
- Gloria Andres A
- Goetghebuer T
- Gomez Sirvent J
- Goodall R
- Gordon A
- Grande A
- Grawe C
- Greenberg M
- Grivell S
- Guerrero C
- Guillen S
- Gunthard HF
- Gurtin D
- Haerry D
- Hagas V
- Hague R
- Hainaut M
- Hancock J
- Hanpinitsak S
- Hansudewechakul R
- Harper L
- Harrison I
- Hasse B
- Hawkins S
- Henriet SS
- Herranz M
- Hillebregt M
- Hirsch HH
- Hoffmann M
- Hongsiriwon S
- Hosli I
- Huber M
- Ibberson L
- Isabel Gonzalez-Tome M
- Isabel Menasalvas A
- Isabel Piqueras A
- Jaisieng N
- Jareno E
- Jimenez de Ory S
- Jones L
- Jose Mellado M
- Jose Munoz M
- Jose Romero F
- Jourdain G
- Judd A
- Jurriaans S
- Kahlert CR
- Kaiser L
- Kamonpakorn N
- Kanjanavanit S
- Karnchanamayul W
- Kawilapat S
- Keiser O
- Kenny J
- Klein N
- Klein N
- Klimkait T
- Knoester M
- Koopmans MPG
- Koops J
- Kottanattu L
- Kouyos RD
- Kovari H
- Krikajornkitti S
- Kruijne E
- Kuekou HT
- Kwanchaipanich R
- Labutina S
- Larovere D
- Lawtongkum W
- Layangool P
- Le Coeur S
- Le Prevost M
- Lecompte TM
- Ledergerber B
- Lees Y
- Lendinez F
- Lertpienthum N
- Letting G
- Lillo M
- Lipreri R
- Lisi C
- Lo Vecchio A
- Lodewijk C
- Lopez N
- Losada B
- Lucas E
- Lucksanapisitkul P
- Luis Santos J
- Luisa Navarro M
- Lyall H
- Lyall H
- Maccabruni A
- Manyika F
- Marczynska M
- Martinetti G
- Martinez J
- Marugan V
- Marzolini C
- Mateo M
- Mayol L
- Mazza A
- McMaster P
- McMaster P
- Meijering R
- Mekmullica J
- Mendez M
- Menson E
- Metzner KJ
- Miloenko M
- Monrose C
- Montagnani C
- Montesdeoca A
- Montesinos E
- Moreno D
- Mueller N
- Munjishvili L
- Mur A
- Murau F
- Murphy PMC
- Na-Rajsima S
- Nanta S
- Nantarukchaikul M
- Naratee N
- Nauta N
- Naver L
- Neth O
- Ngampiyaskul C
- Nicca D
- Niesters HGM
- Noguera A
- Noguera-Julian A
- Nsangi E
- Ochoa C
- Offerman B
- Okhonskaia L
- Oldakowska A
- Olmeo P
- Paioni P
- Pajkrt D
- Paling E
- Pantaleo G
- Pas SD
- Patrizia O
- Peeck B
- Pellegatta A
- Percival E
- Perez A
- Perez C
- Perez-Hoyos S
- Perreau M
- Peters H
- Phanomcheong S
- Pickering A
- Pineda V
- Pocheville I
- Pokorska-Spiewak M
- Polli C
- Pope S
- Popielska J
- Potchalongsin S
- Price V
- Prieto L
- Prime K
- Prime K
- Puangsombat A
- Raethke M
- Rahamat-Langendoen J
- Rampon O
- Rauch A
- Ree C
- Regtop R
- Reiss P
- Riordan A
- Riordan A
- Rius N
- Rojo P
- Roman V
- Romano A
- Rovira N
- Rudin C
- Ruggeri M
- Ruijs Y
- Ruiz B
- Rutkens T
- Saavedra J
- Sainz T
- Saipanya A
- Salvini F
- Santa A
- Santos M
- Scherpbier H
- Scherpbier HJ
- Scherrer AU
- Schinkel CJ
- Schmid P
- Schnorr P
- Scholvinck EH
- Schoorl M
- Schuurman R
- Seery P
- Segal S
- Segarra I
- Shackley F
- Shackley F
- Sharland M
- Sharpe G
- Shingadia D
- Shingadia D
- Sloper K
- Smit C
- Smit C
- Smyth A
- Soeria-Atmadja S
- Soler-Palacin P
- Southall S
- Speck R
- Spoulou V
- Srirojana S
- Stelma FF
- Stockle M
- Storey S
- Storey S
- Strik-Albers R
- Suaysod R
- Subramaniam B
- Suriyaboon T
- Tagliabue C
- Taramasso L
- Tarr P
- Techakunakorn P
- Terol P
- Than-in-at K
- Thanasiri P
- Theansavettrakul S
- Thompson F
- Thorne C
- Thrasyvoulou L
- Tomas Ramos J
- Tovo PA
- Trkola A
- Tudor-Williams G
- Tudor-Williams G
- Tuijn E
- Tuk B
- Turkova A
- Vallmanya T
- Van Aerde K
- Van de Flier M
- Van de Sande L
- Van den Akker M
- Van der Kelen E
- Van der Knaap LC
- Van der Meer R
- Van der Vliet S
- Van Kampen JJA
- Van Leer-Buter CC
- Van Looy N
- Van Rossum AMC
- Van Sighem A
- Veenenberg L
- Venturini E
- Verduyn-Lunel F
- Vermont CL
- Vernazza P
- Visser EG
- Voronin E
- Wagner N
- Walsh A
- Wanchaitanawong V
- Wandeler G
- Wannarit P
- Warachit B
- Watanayothin S
- Weber R
- Weijsenfeld AM
- Welch S
- Welch S
- Wensing AMJ
- Williams B
- Wisse A
- Wit FWMN
- Witte EC
- Wolfs TFW
- Wolthers KC
- Woudstra T
- Wyler CA
- Yannoulias A
- Yeadon S
- Yerly S
- Zaaijer HL
- Zaheri S
- Zawadka K
- Publication venue
- 'Ovid Technologies (Wolters Kluwer Health)'
- Publication date
- 01/01/2019
- Field of study
OBJECTIVE: The aim of this study was to describe growth during puberty in young people with vertically acquired HIV. DESIGN: Pooled data from 12 paediatric HIV cohorts in Europe and Thailand. METHODS: One thousand and ninety-four children initiating a nonnucleoside reverse transcriptase inhibitor or boosted protease inhibitor based regimen aged 1-10 years were included. Super Imposition by Translation And Rotation (SITAR) models described growth from age 8 years using three parameters (average height, timing and shape of the growth spurt), dependent on age and height-for-age z-score (HAZ) (WHO references) at antiretroviral therapy (ART) initiation. Multivariate regression explored characteristics associated with these three parameters. RESULTS: At ART initiation, median age and HAZ was 6.4 [interquartile range (IQR): 2.8, 9.0] years and -1.2 (IQR: -2.3 to -0.2), respectively. Median follow-up was 9.1 (IQR: 6.9, 11.4) years. In girls, older age and lower HAZ at ART initiation were independently associated with a growth spurt which occurred 0.41 (95% confidence interval 0.20-0.62) years later in children starting ART age 6 to 10 years compared with 1 to 2 years and 1.50 (1.21-1.78) years later in those starting with HAZ less than -3 compared with HAZ at least -1. Later growth spurts in girls resulted in continued height growth into later adolescence. In boys starting ART with HAZ less than -1, growth spurts were later in children starting ART in the oldest age group, but for HAZ at least -1, there was no association with age. Girls and boys who initiated ART with HAZ at least -1 maintained a similar height to the WHO reference mean. CONCLUSION: Stunting at ART initiation was associated with later growth spurts in girls. Children with HAZ at least -1 at ART initiation grew in height at the level expected in HIV negative children of a comparable age
Height and timing of growth spurt during puberty in young people living with vertically acquired HIV in Europe and Thailand
- Author
- Alvarez S.
- Angulo R.
- Apilanez M.
- Back NKT.
- Badillo K.
- Badolato R.
- Bakker Y.
- Baldi F.
- Beceiro J.
- Belfrage E.
- Bergsma D.
- Berkhout B.
- Bernardi S.
- Bezemer DO.
- Bezemer M.
- Blazquez D.
- Bont LJ.
- Boucher CAB.
- Bruzzese E.
- Bustillo M.
- Calavia O.
- Cellini M.
- Colino E.
- Coll M.
- Collado P.
- Collins I.J.
- Consolini R.
- Cornelissen MTE.
- Couceiro JA.
- Coupland U.
- Crichton S.
- Cristiano L.
- de Boer CG.
- de Groot L.
- de Groot-de Jonge H.
- de Jong A.
- de Martino M.
- de Ory SJ.
- de Tejada BM.
- Decker L.
- Delforge M.
- Di Biagio A.
- Dodi I.
- Doerholt K.
- Dona D.
- Doroba M.
- Duenas J.
- El Berkaoui A.
- Ene L.
- Erba P.
- Escosa L.
- Esposito S.
- Falcon L.
- Faldella G.
- Fortuny C.
- Fraaij PLA.
- Frick MA.
- Gabiano C.
- Galli L.
- Gamell A.
- Garazzino S.
- Garcia L.
- Garrote E.
- Garzon M.
- Geelen SPM.
- Geerlinks J.
- Genovese O.
- Giacomet V.
- Giaquinto C.
- Gibb D.M.
- Goetghebuer T.
- Gonzalez-Tome MI.
- Goodall R.
- Grande A.
- Grivell S.
- Guerrero C.
- Guillen S.
- Hainaut M.
- Henriet SSV.
- Herranz M.
- Hillebregt M.
- Hortelano MG.
- Jourdain G.
- Judd A.
- Jurriaans S.
- Knoester M.
- Koopmans MPG.
- Koops J.
- Kruijne E.
- Kuekou HT.
- Labutina S.
- Larovere D.
- Le Coeur S.
- Lendinez F.
- Lillo M.
- Lipreri R.
- Lisi C.
- Lo Vecchio A.
- Lodewijk C.
- Lopez N.
- Losada B.
- Lucas E.
- Maccabruni A.
- Marczynska M.
- Martinez J.
- Mateo M.
- Mayol L.
- Mazza A.
- Mc Phee CF.
- Meijering R.
- Mellado MJ.
- Mendez M.
- Miloenko M.
- Montagnani C.
- Montesdeoca A.
- Moreno D.
- Munjishvili L.
- Munoz MA.
- Munoz MJ.
- Mur A.
- Nauta N.
- Navarro M.L.
- Neth O.
- Niesters HGM.
- Noguera A.
- Noguera-Julian A.
- Okhonskaia L.
- Oldakowska A.
- Olmeo P.
- Pajkrt D.
- Paling E.
- Pas SD.
- Patrizia O.
- Peeck B.
- Pellegatta A.
- Perez A.
- Perez C.
- Perez-Hoyos S.
- Pineda V.
- Pocheville I.
- Pokorska-Spiewak M.
- Popielska J.
- Prieto L.
- Raethke M.
- Rahamat-Langendoen J.
- Ramos J.T.
- Rampon O.
- Ree C.
- Regtop R.
- Reiss P.
- Rius N.
- Roa MA.
- Rojo P.
- Roman V.
- Romano A.
- Romero FJ.
- Rovira N.
- Ruggeri M.
- Ruijs Y.
- Ruiz B.
- Rutkens T.
- Saavedra J.
- Sainz T.
- Salvini F.
- Santa Ansone.
- Santos JL.
- Santos M.
- Scherpbier H.
- Scherpbier HJ.
- Schinkel CJ.
- Schnorr P.
- Scholvinck EH.
- Schoorl M.
- Schuurman R.
- Sirvent JG.
- Smit C.
- Smit C.
- Soler-Palacin P.
- Spoulou V.
- Stelma FF.
- Strik-Albers R.
- Tagliabue C.
- Taramasso L.
- Terol P.
- Thorne C.
- Tovo PA.
- Tuijn E.
- Tuk B.
- Vallmanya T.
- van Aerde K.
- van de Flier M.
- van de Sande L.
- van den Akker M.
- Van der Kelen E.
- van der Knaap LC.
- van der Meer R.
- van der Vliet S.
- van Kampen JJA.
- van Leer-Buter CC.
- van Rossum AMC.
- van Sighem AI.
- Veenenberg L.
- Venturini E.
- Verduyn-Lunel F.
- Vermont CL.
- Visser EG.
- Voronin E.
- Weijsenfeld AM.
- Wensing AMJ.
- Wisse A.
- Wit FWMN.
- Witte EC.
- Wolfs TFW.
- Wolthers KC.
- Woudstra T.
- Zaaijer HL.
- Zaheri S.
- Zawadka K.
- Publication venue
- 'Ovid Technologies (Wolters Kluwer Health)'
- Publication date
- 01/01/2019
- Field of study
Objective: The aim of this study was to describe growth during puberty in young people with vertically acquired HIV.
Design: Pooled data from 12 paediatric HIV cohorts in Europe and Thailand.
Methods: One thousand and ninety-four children initiating a nonnucleoside reverse transcriptase inhibitor or boosted protease inhibitor based regimen aged 1-10 years were included. Super Imposition by Translation And Rotation (SITAR) models described growth from age 8 years using three parameters (average height, timing and shape of the growth spurt), dependent on age and height-for-age z-score (HAZ) (WHO references) at antiretroviral therapy (ART) initiation. Multivariate regression explored characteristics associated with these three parameters.
Results: At ART initiation, median age and HAZ was 6.4 [interquartile range (IQR): 2.8, 9.0] years and -1.2 (IQR: -2.3 to -0.2), respectively. Median follow-up was 9.1 (IQR: 6.9, 11.4) years. In girls, older age and lower HAZ at ART initiation were independently associated with a growth spurt which occurred 0.41 (95% confidence interval 0.20-0.62) years later in children starting ART age 6 to 10 years compared with 1 to 2 years and 1.50 (1.21-1.78) years later in those starting with HAZ less than -3 compared with HAZ at least -1. Later growth spurts in girls resulted in continued height growth into later adolescence. In boys starting ART with HAZ less than -1, growth spurts were later in children starting ART in the oldest age group, but for HAZ at least -1, there was no association with age. Girls and boys who initiated ART with HAZ at least -1 maintained a similar height to the WHO reference mean.
Conclusion: Stunting at ART initiation was associated with later growth spurts in girls. Children with HAZ at least -1 at ART initiation grew in height at the level expected in HIV negative children of a comparable age
Charged-particle distributions at low transverse momentum in âs=13 13 TeV pp interactions measured with the ATLAS detector at the LHC
- Author
- Aaboud M
- Aad G
- Abbott B
- Abdallah J
- Abdinov O
- Abeloos B
- Aben R
- AbouZeid OS
- Abraham NL
- Abramowicz H
- Abreu H
- Abreu R
- Abulaiti Y
- Acharya BS
- Adam ER
- Adamczyk L
- Adams DL
- Adelman J
- Adomeit S
- Adye T
- Affolder AA
- Agatonovic-Jovin T
- Agricola J
- Aguilar-Saavedra JA
- Ahlen SP
- Ahmadov F
- Aielli G
- Akerstedt H
- Akesson TPA
- Akimov AV
- Alberghi GL
- Alberich LC
- Albert J
- Albrand S
- Aleksa M
- Aleksandrov IN
- Alexa C
- Alexander G
- Alexopoulos T
- Alhroob M
- Ali B
- Aliev M
- Alimonti G
- Alison J
- Alkire SP
- Allbrooke BMM
- Allen BW
- Allport PP
- Aloisio A
- Alonso A
- Alonso F
- Alpigiani C
- Alstaty M
- Alviggi MG
- Amadio BT
- Amako K
- Amelung C
- Amidei D
- Amorim A
- Amoroso S
- Amundsen G
- Anastopoulos C
- Ancu LS
- Andari N
- Andeen T
- Anders CF
- Anders G
- Anders JK
- Anderson KJ
- Andreazza A
- Andrei V
- Angelidakis S
- Angelozzi I
- Anger P
- Angerami A
- Anghinolfi F
- Anisenkov AV
- Anjos N
- Annovi A
- Antel C
- Antonelli M
- Antonov A
- Anulli F
- Aoki M
- Arabidze G
- Arai Y
- Aranda CP
- Araque JP
- Araya ST
- Arce ATH
- Arduh FA
- Arguin J-F
- Argyropoulos S
- Arik M
- Armadans RC
- Armbruster AJ
- Armitage LJ
- Arnaez O
- Arnold H
- Arratia M
- Arslan O
- Artamonov A
- Artoni G
- Artz S
- Asai S
- Asbah N
- Ashkenazi A
- Asman B
- Asquith L
- Assamagan K
- Astalos R
- Astigarraga MEP
- Atkinson M
- Atlay NB
- Augsten K
- Avolio G
- Axen B
- Ayoub MK
- Azuelos G
- Baak MA
- Baas AE
- Baca MJ
- Bachacou H
- Bachas K
- Backes M
- Backhaus M
- Bagiacchi P
- Bagnaia P
- Bai Y
- Baines JT
- Baker OK
- Baldin EM
- Balek P
- Balestri T
- Balli F
- Balunas WK
- Banas E
- Banerjee S
- Bannoura AAE
- Barajas CAC
- Barak L
- Barberio EL
- Barberis D
- Barbero M
- Barillari T
- Barisits M-S
- Barklow T
- Barlow N
- Barnes SL
- Barnett BM
- Barnett RM
- Barnovska Z
- Baroncelli A
- Barone G
- Barr AJ
- Barreiro F
- Bartoldus R
- Barton AE
- Bartos P
- Basalaev A
- Bassalat A
- Bates RL
- Batista SJ
- Batley JR
- Battaglia M
- Bauce M
- Bauer F
- Bawa HS
- Beacham JB
- Beattie MD
- Beau T
- Beauchemin PH
- Bechtle P
- Beck HP
- Becker K
- Becker M
- Beckingham M
- Becot C
- Beddall A
- Beddall AJ
- Bednyakov VA
- Bedognetti M
- Bee CP
- Beemster LJ
- Beermann TA
- Begel M
- Behr JK
- Belanger-Champagne C
- Bell AS
- Bella G
- Bella LA
- Bellagamba L
- Bellerive A
- Bellomo M
- Belotskiy K
- Beltramello O
- Belyaev NL
- Benary O
- Benchekroun D
- Bender M
- Bendtz K
- Benekos N
- Benhammou Y
- Benitez J
- Benjamin DP
- Bensinger JR
- Bentvelsen S
- Beresford L
- Beretta M
- Berge D
- Berger N
- Beringer J
- Berlendis S
- Berlingen JM
- Bernard NR
- Bernius C
- Bernlochner FU
- Berry T
- Berta P
- Bertella C
- Bertoli G
- Bertolucci F
- Bertram IA
- Bertsche C
- Bertsche D
- Besjes GJ
- Bessner M
- Besson N
- Betancourt C
- Bethke S
- Bevan AJ
- Bhimji W
- Bianchi RM
- Bianchini L
- Bianco M
- Biebel O
- Biedermann D
- Bielski R
- Biesuz NV
- Biglietti M
- Bilokon H
- Bindi M
- Binet S
- Bingul A
- Bini C
- Biondi S
- Bjergaard DM
- Black CW
- Black JE
- Black KM
- Blackburn D
- Blair RE
- Blanchard J-B
- Blanco JE
- Blazek T
- Bloch I
- Blocker C
- Blum W
- Blumenschein U
- Blunier S
- Bobbink GJ
- Bobrovnikov VS
- Bocchetta SS
- Bocci A
- Bock C
- Boehler M
- Boeriu OEV
- Boerner D
- Bogaerts JA
- Bogavac D
- Bogdanchikov AG
- Bohm C
- Boisvert V
- Bokan P
- Bold T
- Boldyrev AS
- Bomben M
- Bona M
- Boonekamp M
- Borisov A
- Borissov G
- Bortfeldt J
- Bortoletto D
- Bortolotto V
- Bos K
- Boscherini D
- Bosman M
- Boudreau J
- Bouffard J
- Bouhova-Thacker EV
- Boumediene D
- Bourdarios C
- Boutle SK
- Boveia A
- Boyd J
- Boyko IR
- Bracinik J
- Brandt A
- Brandt G
- Brandt O
- Bratzler U
- Brau B
- Brau JE
- Braun HM
- Bravo AG
- Brendlinger K
- Brennan AJ
- Brenner L
- Brenner R
- Bressler S
- Bret MC
- Bristow TM
- Britton D
- Britzger D
- Brochu FM
- Brock I
- Brock R
- Brooijmans G
- Brooks T
- Brooks WK
- Brosamer J
- Brost E
- Broughton JH
- Bruncko D
- Bruneliere R
- Bruni A
- Bruni G
- Bruni LS
- Brunt BH
- Bruschi M
- Bruscino N
- Bryant P
- Bryngemark L
- Buanes T
- Buat Q
- Buchholz P
- Buckley AG
- Budagov IA
- Buehrer F
- Bugge MK
- Bulekov O
- Bullock D
- Burckhart H
- Burdin S
- Burgard CD
- Burghgrave B
- Burka K
- Burke S
- Burmeister I
- Burr JTP
- Busato E
- Buscher D
- Buscher V
- Bussey P
- Butler JM
- Buttar CM
- Butterworth JM
- Butti P
- Buttinger W
- Buzatu A
- Buzykaev AR
- Bylund OB
- Caforio D
- Cairo VM
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- Zaitsev AM
- Zakharchuk N
- Zalieckas J
- Zaman A
- Zambito S
- Zanello L
- Zanzi D
- Zeitnitz C
- Zeman M
- Zemla A
- Zeng JC
- Zeng Q
- Zengel K
- Zenin O
- Zenis T
- Zerwas D
- Zhang D
- Zhang F
- Zhang G
- Zhang H
- Zhang J
- Zhang L
- Zhang R
- Zhang R
- Zhang X
- Zhang Z
- Zhao X
- Zhao Y
- Zhao Z
- Zhemchugov A
- Zhong J
- Zhou B
- Zhou C
- Zhou L
- Zhou L
- Zhou M
- Zhou N
- Zhu CG
- Zhu H
- Zhu J
- Zhu Y
- Zhuang X
- Zhukov K
- Zibell A
- Zieminska D
- Zimine NI
- Zimmermann C
- Zimmermann S
- Zinonos Z
- Zinser M
- Ziolkowski M
- Zivkovic L
- Zobernig G
- Zoccoli A
- Zwalinski L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2016
- Field of study
Measurements of distributions of charged particles produced in protonâproton collisions with a centre-of-mass energy of 13 TeV are presented. The data were recorded by the ATLAS detector at the LHC and correspond to an integrated luminosity of 151 ÎŒb â1 ÎŒbâ1 . The particles are required to have a transverse momentum greater than 100 MeV and an absolute pseudorapidity less than 2.5. The charged-particle multiplicity, its dependence on transverse momentum and pseudorapidity and the dependence of the mean transverse momentum on multiplicity are measured in events containing at least two charged particles satisfying the above kinematic criteria. The results are corrected for detector effects and compared to the predictions from several Monte Carlo event generators
Measurement of W+Wâ production in association with one jet in protonâproton collisions at sqrt(s) = 8TeV with the ATLAS detector
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- Aad G
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- Abdallah J
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- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2016
- Field of study
The production of W boson pairs in association with one jet in pp collisions at View the MathML sources=8 TeV is studied using data corresponding to an integrated luminosity of 20.3 fbâ1 collected by the ATLAS detector during 2012 at the CERN Large Hadron Collider. The cross section is measured in a fiducial phase-space region defined by the presence of exactly one electron and one muon, missing transverse momentum and exactly one jet with a transverse momentum above 25 GeV and a pseudorapidity of |η|<4.5|η|<4.5. The leptons are required to have opposite electric charge and to pass transverse momentum and pseudorapidity requirements. The fiducial cross section is found to be View the MathML sourceÏWWfid,1-jet=136±6(stat)±14(syst)±3(lumi) fb. In combination with a previous measurement restricted to leptonic final states with no associated jets, the fiducial cross section of WW production with zero or one jet is measured to be View the MathML sourceÏWWfid,â€1-jet=511±9(stat)±26(syst)±10(lumi) fb. The ratio of fiducial cross sections in final states with one and zero jets is determined to be 0.36±0.050.36±0.05. Finally, a total cross section extrapolated from the fiducial measurement of WW production with zero or one associated jet is reported. The measurements are compared to theoretical predictions and found in good agreement
Measurement of VH, H â b b ÂŻ production as a function of the vector-boson transverse momentum in 13 TeV pp collisions with the ATLAS detector
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- Zhemchugov A
- Zheng Z
- Zhong D
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- Zhulanov V
- Zieminska D
- Zimine NI
- Zimmermann S
- Zinonos Z
- Ziolkowski M
- Zivkovic L
- Zobernig G
- Zoccoli A
- Zoch K
- Zorbas TG
- Zou R
- Zu Theenhausen HM
- Zwalinski L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2019
- Field of study
Cross-sections of associated production of a Higgs boson decaying into bottom-quark pairs and an electroweak gauge boson, W or Z, decaying into leptons are measured as a function of the gauge boson transverse momentum. The measurements are performed in kinematic fiducial volumes defined in the `simplified template cross-section' framework. The results are obtained using 79.8 fb-1 of proton-proton collisions recorded by the ATLAS detector at the Large Hadron Collider at a centre-of-mass energy of 13 TeV. All measurements are found to be in agreement with the Standard Model predictions, and limits are set on the parameters of an effective Lagrangian sensitive to modifications of the Higgs boson couplings to the electroweak gauge bosons
Search for pair production of Higgs bosons in the bbÂŻbbÂŻ final state using proton-proton collisions at âs=13ââTeV with the ATLAS detector
- Author
- Aaboud M
- Aad G
- Abbott B
- Abdallah J
- Abdinov O
- Abeloos B
- Aben R
- AbouZeid OS
- Abraham NL
- Abramowicz H
- Abreu H
- Abreu R
- Abulaiti Y
- Acharya BS
- Adamczyk L
- Adams DL
- Adelman J
- Adomeit S
- Adye T
- Affolder AA
- Agatonovic-Jovin T
- Agricola J
- Aguilar-Saavedra JA
- Ahlen SP
- Ahmadov F
- Aielli G
- Akerstedt H
- Akesson TPA
- Akimov AV
- Alberghi GL
- Alberich LC
- Albert J
- Albrand S
- Aleksa M
- Aleksandrov IN
- Alexa C
- Alexander G
- Alexopoulos T
- Alhroob M
- Aliev M
- Alimonti G
- Alison J
- Alkire SP
- Allbrooke BMM
- Allen BW
- Allport PP
- Aloisio A
- Alonso A
- Alonso F
- Alpigiani C
- Alstaty M
- Alviggi MG
- Amadio BT
- Amako K
- Amelung C
- Amidei D
- Amorim A
- Amoroso S
- Amundsen G
- Anastopoulos C
- Ancu LS
- Andari N
- Andeen T
- Anders CF
- Anders G
- Anders JK
- Anderson KJ
- Andreazza A
- Andrei V
- Angelidakis S
- Angelozzi I
- Anger P
- Angerami A
- Anghinolfi F
- Anisenkov AV
- Anjos N
- Annovi A
- Antonelli M
- Antonov A
- Anulli F
- Aoki M
- Arabidze G
- Arai Y
- Araque JP
- Arce ATH
- Arduh FA
- Arguin J-F
- Argyropoulos S
- Arik M
- Armadans RC
- Armbruster AJ
- Armitage LJ
- Arnaez O
- Arnold H
- Arratia M
- Arslan O
- Artamonov A
- Artoni G
- Artz S
- Asai S
- Asbah N
- Ashkenazi A
- Asman B
- Asquith L
- Assamagan K
- Astalos R
- Astigarraga MEP
- Atkinson M
- Atlay NB
- Augsten K
- Avolio G
- Axen B
- Ayoub MK
- Azuelos G
- Baak MA
- Baas AE
- Baca MJ
- Bachacou H
- Bachas K
- Backes M
- Backhaus M
- Bagiacchi P
- Bagnaia P
- Bai Y
- Baines JT
- Baker OK
- Baldin EM
- Balek P
- Balestri T
- Balli F
- Balunas WK
- Banas E
- Banerjee S
- Bannoura AAE
- Barajas CAC
- Barak L
- Barberio EL
- Barberis D
- Barbero M
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- Barklow T
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- Barnett BM
- Barnett RM
- Barnovska Z
- Baroncelli A
- Barone G
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- Barreiro F
- Bartoldus R
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- Basalaev A
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- Bates RL
- Batista SJ
- Batley JR
- Battaglia M
- Bauce M
- Bauer F
- Bawa HS
- Beacham JB
- Beattie MD
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- Beauchemin PH
- Bechtle P
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- Zobernig G
- Zoccoli A
- Zu Theenhausen HM
- Zur Nedden M
- Zurzolo G
- Zwalinski L
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 01/01/2016
- Field of study
A search for Higgs-boson pair production in the bb ÂŻ bb ÂŻ final state is carried out with 3.2ââfb â1 of proton-proton collision data collected at s â =13ââTeV with the ATLAS detector. The data are consistent with the estimated background and are used to set upper limits on the production cross section of Higgs-boson pairs times branching ratio to bb ÂŻ bb ÂŻ for both nonresonant and resonant production. In the case of resonant production of Kaluza-Klein gravitons within the Randall-Sundrum model, upper limits in the 24 to 91 fb range are obtained for masses between 600 and 3000 GeV, at the 95% confidence level. The production cross section times branching ratio for nonresonant Higgs-boson pairs is also constrained to be less than 1.22 pb, at the 95% confidence level
Spontaneous Breathing in Early Acute Respiratory Distress Syndrome: Insights From the Large Observational Study to UNderstand the Global Impact of Severe Acute Respiratory FailurE Study
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- Vercueil A
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- Zogheib EH
- Ăamendys-Silva SA
- Ănal N
- Publication venue
- 'Ovid Technologies (Wolters Kluwer Health)'
- Publication date
- 01/01/2019
- Field of study
OBJECTIVES: To describe the characteristics and outcomes of patients with acute respiratory distress syndrome with or without spontaneous breathing and to investigate whether the effects of spontaneous breathing on outcome depend on acute respiratory distress syndrome severity. DESIGN: Planned secondary analysis of a prospective, observational, multicentre cohort study. SETTING: International sample of 459 ICUs from 50 countries. PATIENTS: Patients with acute respiratory distress syndrome and at least 2 days of invasive mechanical ventilation and available data for the mode of mechanical ventilation and respiratory rate for the 2 first days. INTERVENTIONS: Analysis of patients with and without spontaneous breathing, defined by the mode of mechanical ventilation and by actual respiratory rate compared with set respiratory rate during the first 48 hours of mechanical ventilation. MEASUREMENTS AND MAIN RESULTS: Spontaneous breathing was present in 67% of patients with mild acute respiratory distress syndrome, 58% of patients with moderate acute respiratory distress syndrome, and 46% of patients with severe acute respiratory distress syndrome. Patients with spontaneous breathing were older and had lower acute respiratory distress syndrome severity, Sequential Organ Failure Assessment scores, ICU and hospital mortality, and were less likely to be diagnosed with acute respiratory distress syndrome by clinicians. In adjusted analysis, spontaneous breathing during the first 2 days was not associated with an effect on ICU or hospital mortality (33% vs 37%; odds ratio, 1.18 [0.92-1.51]; p = 0.19 and 37% vs 41%; odds ratio, 1.18 [0.93-1.50]; p = 0.196, respectively ). Spontaneous breathing was associated with increased ventilator-free days (13 [0-22] vs 8 [0-20]; p = 0.014) and shorter duration of ICU stay (11 [6-20] vs 12 [7-22]; p = 0.04). CONCLUSIONS: Spontaneous breathing is common in patients with acute respiratory distress syndrome during the first 48 hours of mechanical ventilation. Spontaneous breathing is not associated with worse outcomes and may hasten liberation from the ventilator and from ICU. Although these results support the use of spontaneous breathing in patients with acute respiratory distress syndrome independent of acute respiratory distress syndrome severity, the use of controlled ventilation indicates a bias toward use in patients with higher disease severity. In addition, because the lack of reliable data on inspiratory effort in our study, prospective studies incorporating the magnitude of inspiratory effort and adjusting for all potential severity confounders are required
Identifying associations between diabetes and acute respiratory distress syndrome in patients with acute hypoxemic respiratory failure: an analysis of the LUNG SAFE database
- Author
- Abad Rd
- Abe T
- Abroug F
- Adams Jc
- Adamsson Ro
- Adolfsson A
- Aguilar Rz
- Aguirre Js
- Aguirre-Bermeo H
- Aisa Tm
- Aisiku I
- Ajetunmobi Oo
- Aker M
- Akyol Oo
- Al Dorzi Hm
- Al Jabbary As
- Albaiceta Gm
- Albarrak Mm
- Albiero D
- Alda Rs
- Alejandro Rv
- Alexander P
- Algaba Ă
- Aliaga Fa
- Alisasis Au
- Allan Rm
- Allue Rm
- Almekhlafi G
- Alonso Jg
- Altaf W
- Alvarez Am
- Alvarez J
- Amin P
- Amir F
- Amor M
- An Y
- Andersen Fh
- Andoh K
- Andruszkiewicz P
- Aneman A
- Antonelli Mm
- AntĂŽnio Acp
- Aoki N
- Appelberg H
- Arabi Y
- Arabi Ym
- Arabi Ym
- Araujo Am
- Arizmendi A
- Arnal Jm
- Artiga Mjd
- Artigas A
- Ascoli A
- Au Sm
- Avila Le
- Azad R
- Azevedo Lc
- Baboi L
- Badie Jc
- Bailey Im
- Bailey Mb
- Bajwa E
- Balkhi H
- Baltus T
- Banner-Goodspeed Vm
- Barberet G
- Baron Rm
- Baronia Ak
- Barratt-Due A
- Barros Fm
- Barros Nc
- Batra H
- Battle Ce
- Bauer Pr
- Beck E
- Beck O
- Bedreag Oh
- Beegle Sh
- Beitler Jr
- Bellani G
- Bellani Giacomo
- Beloncle F
- Benslama A
- Beraldo Do
- Berkelmans F
- Besset Sl
- Bettini Lr
- Beuret P
- Bezzi Mg
- Bhardwaj Vk
- Bhowmick K
- Biehler J
- Bihari S
- Biondi Rs
- Biscione Rr
- Bisso Mc
- Black Cs
- Blakeman Tc
- Blanco J
- Bolon S
- Borello Sa
- Borotto Ee
- Botteri M
- Bouchoucha S
- Boukhazna M
- Bouw Mj
- Boyd O
- Boyle Andrew J.
- Bramall J
- Braschi A
- Braschi A
- Brazzi L
- Breen Dm
- Briquet A
- Brito Va
- Brizuela M
- Broman Lm
- Brown Sm
- Browne Ts
- Bruhn Scar
- Brunettini B
- Bruns Mm
- Buensuseso Ja
- Bugedo G
- Buise Mp
- Bulpa Pa
- Bumbasierevic V
- Bumbasirevic V
- Burtenshaw Aj
- Burtin P
- Buzancais G
- BĂ©duneau G
- Camsooksai J
- Cani A
- Carbayo-Gorriz C
- Cardonnet Lp
- Careless Jp
- Carpentier D
- Carreño Ng
- Carteaux G
- Casalena P
- Casement J
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- Ăamendys-Silva Sa
- Ănal N
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2018
- Field of study
Background: Diabetes mellitus is a common co-existing disease in the critically ill. Diabetes mellitus may reduce the risk of acute respiratory distress syndrome (ARDS), but data from previous studies are conflicting. The objective of this study was to evaluate associations between pre-existing diabetes mellitus and ARDS in critically ill patients with acute hypoxemic respiratory failure (AHRF). Methods: An ancillary analysis of a global, multi-centre prospective observational study (LUNG SAFE) was undertaken. LUNG SAFE evaluated all patients admitted to an intensive care unit (ICU) over a 4-week period, that required mechanical ventilation and met AHRF criteria. Patients who had their AHRF fully explained by cardiac failure were excluded. Important clinical characteristics were included in a stepwise selection approach (forward and backward selection combined with a significance level of 0.05) to identify a set of independent variables associated with having ARDS at any time, developing ARDS (defined as ARDS occurring after day 2 from meeting AHRF criteria) and with hospital mortality. Furthermore, propensity score analysis was undertaken to account for the differences in baseline characteristics between patients with and without diabetes mellitus, and the association between diabetes mellitus and outcomes of interest was assessed on matched samples. Results: Of the 4107 patients with AHRF included in this study, 3022 (73.6%) patients fulfilled ARDS criteria at admission or developed ARDS during their ICU stay. Diabetes mellitus was a pre-existing co-morbidity in 913 patients (22.2% of patients with AHRF). In multivariable analysis, there was no association between diabetes mellitus and having ARDS (OR 0.93 (0.78-1.11); p = 0.39), developing ARDS late (OR 0.79 (0.54-1.15); p = 0.22), or hospital mortality in patients with ARDS (1.15 (0.93-1.42); p = 0.19). In a matched sample of patients, there was no association between diabetes mellitus and outcomes of interest. Conclusions: In a large, global observational study of patients with AHRF, no association was found between diabetes mellitus and having ARDS, developing ARDS, or outcomes from ARDS. Trial registration: NCT02010073. Registered on 12 December 2013
Epidemiology and patterns of tracheostomy practice in patients with acute respiratory distress syndrome in ICUs across 50 countries
- Author
- Abad RD
- Abe T
- Abe T.
- Abroug F
- Adams JC
- Adamsson RO
- Adolfsson A
- Aguilar RZ
- Aguirre JS
- Aguirre-Bermeo H
- Aisa TM
- Aisiku I
- Ajetunmobi OO
- Aker M
- Akyol OO
- Al Dorzi HM
- Al Jabbary AS
- Albaiceta GM
- Albarrak MM
- Albiero D
- Alda RS
- Alejandro RV
- Alexander P
- Algaba Ă
- Aliaga FA
- Alisasis AU
- Allan RM
- Allue RM
- Almekhlafi G
- Alonso JG
- Altaf W
- Alvarez AM
- Alvarez J
- Amin P
- Amir F
- Amor M
- An Y
- Andersen FH
- Andoh K
- Andruszkiewicz P
- Aneman A
- Antonelli MM
- AntĂŽnio ACP
- Aoki N
- Appelberg H
- Arabi Y
- Arabi YM
- Arabim YM
- Araujo AM
- Arizmendi A
- Arnal JM
- Artiga MJD
- Artigas A
- Ascoli A
- Au SM
- Avila LE
- Azad R
- Azevedo LC
- Baboi L
- Badie JC
- Bailey IM
- Bailey MB
- Bajwa E
- Balkhi H
- Baltus T
- Banner-Goodspeed VM
- Barberet G
- Baron RM
- Baronia AK
- Barratt-Due A
- Barros FM
- Barros NC
- Batra H
- Battle CE
- Bauer PR
- Beck E
- Beck O
- Bedreag OH
- Beegle SH
- Beitler JR
- Bellani G
- Bellani G.
- Beloncle F
- Benslama A
- Beraldo DO
- Berghe C
- Berkelmans F
- Besset SL
- Bettini LR
- Beuret P
- Bezzi MG
- Bhardwaj VK
- Bhowmick K
- Biehler J
- Bigot C
- Bihari S
- Biondi RS
- Biscione RR
- Bisso MC
- Black CS
- Blakeman TC
- Blanco J
- Bolon S
- Borello SA
- Borotto EE
- Botteri M
- Bouchoucha S
- Boukhazna M
- Bouw MJ
- Boyd O
- Bramall J
- Braschi A
- Brazzi L
- Breen DM
- Briquet A
- Brito VA
- Brizuela M
- Brochard L
- Broman LM
- Brown SM
- Browne TS
- Bruhn AR
- Brunettini B
- Bruns MM
- Buensuseso JA
- Bugedo G
- Buise MP
- Bulpa PA
- Bumbasierevic V
- Bumbasirevic V
- Burtenshaw AJ
- Burtin P
- Buzancais G
- BĂ©duneau G
- Camsooksai J
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- Ăamendys-Silva SA
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- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2018
- Field of study
Background: To better understand the epidemiology and patterns of tracheostomy practice for patients with acute respiratory distress syndrome (ARDS), we investigated the current usage of tracheostomy in patients with ARDS recruited into the Large Observational Study to Understand the Global Impact of Severe Acute Respiratory Failure (LUNG-SAFE) study. Methods: This is a secondary analysis of LUNG-SAFE, an international, multicenter, prospective cohort study of patients receiving invasive or noninvasive ventilation in 50 countries spanning 5 continents. The study was carried out over 4 weeks consecutively in the winter of 2014, and 459 ICUs participated. We evaluated the clinical characteristics, management and outcomes of patients that received tracheostomy, in the cohort of patients that developed ARDS on day 1-2 of acute hypoxemic respiratory failure, and in a subsequent propensity-matched cohort. Results: Of the 2377 patients with ARDS that fulfilled the inclusion criteria, 309 (13.0%) underwent tracheostomy during their ICU stay. Patients from high-income European countries (n = 198/1263) more frequently underwent tracheostomy compared to patients from non-European high-income countries (n = 63/649) or patients from middle-income countries (n = 48/465). Only 86/309 (27.8%) underwent tracheostomy on or before day 7, while the median timing of tracheostomy was 14 (Q1-Q3, 7-21) days after onset of ARDS. In the subsample matched by propensity score, ICU and hospital stay were longer in patients with tracheostomy. While patients with tracheostomy had the highest survival probability, there was no difference in 60-day or 90-day mortality in either the patient subgroup that survived for at least 5 days in ICU, or in the propensity-matched subsample. Conclusions: Most patients that receive tracheostomy do so after the first week of critical illness. Tracheostomy may prolong patient survival but does not reduce 60-day or 90-day mortality. Trial registration: ClinicalTrials.gov, NCT02010073. Registered on 12 December 2013
A search for pair-produced resonances in four-jet final states at root s=13 TeV with the ATLAS detector
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- Zhang P
- Zhang R
- Zhang R
- Zhang X
- Zhang Y
- Zhang Z
- Zhao X
- Zhao Y
- Zhao Z
- Zhemchugov A
- Zhou B
- Zhou C
- Zhou L
- Zhou M
- Zhou M
- Zhou N
- Zhu CG
- Zhu H
- Zhu J
- Zhu Y
- Zhuang X
- Zhukov K
- Zibell A
- Zieminska D
- Zimine NI
- Zimmermann C
- Zimmermann S
- Zinonos Z
- Zinser M
- Ziolkowski M
- Zivkovic L
- Zobernig G
- Zoccoli A
- Zou R
- zur Nedden M
- Zwalinski L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 03/04/2017
- Field of study
A search for massive coloured resonances which are pair-produced and decay into two jets is presented. The analysis uses 36.7 fbâ1
â
1
of â
s
= 13 TeV pp collision data recorded by the ATLAS experiment at the LHC in 2015 and 2016. No significant deviation from the background prediction is observed. Results are interpreted in a SUSY simplified model where the lightest supersymmetric particle is the top squark, Ì
t
~
, which decays promptly into two quarks through R-parity-violating couplings. Top squarks with masses in the range 100 GeV<Ì<410
100
GeV
<
m
t
~
<
410
GeV
GeV
are excluded at 95% confidence level. If the decay is into a b-quark and a light quark, a dedicated selection requiring two b-tags is used to exclude masses in the ranges 100 GeV<Ì<470
100
GeV
<
m
t
~
<
470
GeV
GeV
and 480 GeV<Ì<610
480
GeV
<
m
t
~
<
610
GeV
GeV
. Additional limits are set on the pair-production of massive colour-octet resonances
- âŠ