132 research outputs found
From Text to Thought: How Analyzing Language Can Advance Psychological Science
Humans have been using language for millennia but have only just begun to scratch the surface of what natural language can reveal about the mind. Here we propose that language offers a unique window into psychology. After briefly summarizing the legacy of language analyses in psychological science, we show how methodological advances have made these analyses more feasible and insightful than ever before. In particular, we describe how two forms of language analysis?natural-language processing and comparative linguistics?are contributing to how we understand topics as diverse as emotion, creativity, and religion and overcoming obstacles related to statistical power and culturally diverse samples. We summarize resources for learning both of these methods and highlight the best way to combine language analysis with more traditional psychological paradigms. Applying language analysis to large-scale and cross-cultural datasets promises to provide major breakthroughs in psychological science
IMMUNOPATHOLOGICAL STUDIES OF ORTHOTOPIC HUMAN LIVER ALLOGRAFTS
Twenty-six specimens obtained from twenty human orthotopic liver allografts 10-968 days after transplantation were studied by light microscopy, electron microscopy, and immunofluorescence. The main lesions consisted of mononuclear-cell infiltration around the portal tracts, centrilobular cholestasis, liver-cell atrophy and reticulin collapse, obliterative intimal thickening of hepatic arteries, and fibrosis. Moderate amounts of IgG and/or IgM and complement (ÎČ1C/ÎČ1A globulin or C'lq) were observed in four of the liver samples and smaller deposits were present in another five. A further three specimens contained IgG without complement. IgA was detected in only one of the samples. The immunoglobulins were found in the walls of the portal and central veins and of the sinusoids in all thirteen positive liver samples, in the walls of branches of the hepatic artery in three, and in the cytoplasm of some of the mononuclear cells infiltrating the portal tracts in nine of the specimens. Fibrinogen was seen in eight of the samples, usually in the spaces of Disse. Accumulations of immunoglobulins and complement were less frequent in liver than in kidney and heart allografts. These findings suggest that in the failure of human liver allografts cell-mediated immunity and non-immunological factors may be more important than humoral antibody. © 1972
Signatures of Relativistic Neutrinos in CMB Anisotropy and Matter Clustering
We present a detailed analytical study of ultra-relativistic neutrinos in
cosmological perturbation theory and of the observable signatures of
inhomogeneities in the cosmic neutrino background. We note that a modification
of perturbation variables that removes all the time derivatives of scalar
gravitational potentials from the dynamical equations simplifies their solution
notably. The used perturbations of particle number per coordinate, not proper,
volume are generally constant on superhorizon scales. In real space an
analytical analysis can be extended beyond fluids to neutrinos.
The faster cosmological expansion due to the neutrino background changes the
acoustic and damping angular scales of the cosmic microwave background (CMB).
But we find that equivalent changes can be produced by varying other standard
parameters, including the primordial helium abundance. The low-l integrated
Sachs-Wolfe effect is also not sensitive to neutrinos. However, the gravity of
neutrino perturbations suppresses the CMB acoustic peaks for the multipoles
with l>~200 while it enhances the amplitude of matter fluctuations on these
scales. In addition, the perturbations of relativistic neutrinos generate a
*unique phase shift* of the CMB acoustic oscillations that for adiabatic
initial conditions cannot be caused by any other standard physics. The origin
of the shift is traced to neutrino free-streaming velocity exceeding the sound
speed of the photon-baryon plasma. We find that from a high resolution, low
noise instrument such as CMBPOL the effective number of light neutrino species
can be determined with an accuracy of sigma(N_nu) = 0.05 to 0.09, depending on
the constraints on the helium abundance.Comment: 38 pages, 7 figures. Version accepted for publication in PR
Detector Description and Performance for the First Coincidence Observations between LIGO and GEO
For 17 days in August and September 2002, the LIGO and GEO interferometer
gravitational wave detectors were operated in coincidence to produce their
first data for scientific analysis. Although the detectors were still far from
their design sensitivity levels, the data can be used to place better upper
limits on the flux of gravitational waves incident on the earth than previous
direct measurements. This paper describes the instruments and the data in some
detail, as a companion to analysis papers based on the first data.Comment: 41 pages, 9 figures 17 Sept 03: author list amended, minor editorial
change
Search for Gravitational Waves from Primordial Black Hole Binary Coalescences in the Galactic Halo
We use data from the second science run of the LIGO gravitational-wave
detectors to search for the gravitational waves from primordial black hole
(PBH) binary coalescence with component masses in the range 0.2--.
The analysis requires a signal to be found in the data from both LIGO
observatories, according to a set of coincidence criteria. No inspiral signals
were found. Assuming a spherical halo with core radius 5 kpc extending to 50
kpc containing non-spinning black holes with masses in the range 0.2--, we place an observational upper limit on the rate of PBH coalescence
of 63 per year per Milky Way halo (MWH) with 90% confidence.Comment: 7 pages, 4 figures, to be submitted to Phys. Rev.
The Genomes of the Fungal Plant Pathogens Cladosporium fulvum and Dothistroma septosporum Reveal Adaptation to Different Hosts and Lifestyles But Also Signatures of Common Ancestry
We sequenced and compared the genomes of the Dothideomycete fungal plant pathogens Cladosporium fulvum (Cfu) (syn. Passalora fulva) and Dothistroma septosporum (Dse) that are closely related phylogenetically, but have different lifestyles and hosts. Although both fungi grow extracellularly in close contact with host mesophyll cells, Cfu is a biotroph infecting tomato, while Dse is a hemibiotroph infecting pine. The genomes of these fungi have a similar set of genes (70% of gene content in both genomes are homologs), but differ significantly in size (Cfu >61.1-Mb; Dse 31.2-Mb), which is mainly due to the difference in repeat content (47.2% in Cfu versus 3.2% in Dse). Recent adaptation to different lifestyles and hosts is suggested by diverged sets of genes. Cfu contains an a-tomatinase gene that we predict might be required for detoxification of tomatine, while this gene is absent in Dse. Many genes encoding secreted proteins are unique to each species and the repeat-rich areas in Cfu are enriched for these species-specific genes. In contrast, conserved genes suggest common host ancestry. Homologs of Cfu effector genes, including Ecp2 and Avr4, are present in Dse and induce a Cf-Ecp2- and Cf-4-mediated hypersensitive response, respectively. Strikingly, genes involved in production of the toxin dothistromin, a likely virulence factor for Dse, are conserved in Cfu, but their expression differs markedly with essentially no expression by Cfu in planta. Likewise, Cfu has a carbohydrate-degrading enzyme catalog that is more similar to that of necrotrophs or hemibiotrophs and a larger pectinolytic gene arsenal than Dse, but many of these genes are not expressed in planta or are pseudogenized. Overall, comparison of their genomes suggests that these closely related plant pathogens had a common ancestral host but since adapted to different hosts and lifestyles by a combination of differentiated gene content, pseudogenization, and gene regulatio
Measurement of the branching ratio Î(Îbâ° â Ï(2S)Î0)/Î(Îbâ° â J/ÏÎ0) with the ATLAS detector
An observation of the decay and
a comparison of its branching fraction with that of the decay has been made with the ATLAS detector in
proton--proton collisions at TeV at the LHC using an integrated
luminosity of fb. The and mesons are
reconstructed in their decays to a muon pair, while the decay is exploited for the baryon reconstruction. The
baryons are reconstructed with transverse momentum GeV and pseudorapidity . The measured branching ratio of
the and decays is , lower than the expectation from the
covariant quark model.Comment: 12 pages plus author list (28 pages total), 5 figures, 1 table,
published on Physics Letters B 751 (2015) 63-80. All figures are available at
https://atlas.web.cern.ch/Atlas/GROUPS/PHYSICS/PAPERS/BPHY-2013-08
Measurement of the View the tt production cross-section using eÎŒ events with b-tagged jets in pp collisions at âs = 13 TeV with the ATLAS detector
This paper describes a measurement of the inclusive top quark pair production cross-section (ÏttÂŻ) with a data sample of 3.2 fbâ1 of protonâproton collisions at a centre-of-mass energy of âs = 13 TeV, collected in 2015 by the ATLAS detector at the LHC. This measurement uses events with an opposite-charge electronâmuon pair in the final state. Jets containing b-quarks are tagged using an algorithm based on track impact parameters and reconstructed secondary vertices. The numbers of events with exactly one and exactly two b-tagged jets are counted and used to determine simultaneously ÏttÂŻ and the efficiency to reconstruct and b-tag a jet from a top quark decay, thereby minimising the associated systematic uncertainties. The cross-section is measured to be:
ÏttÂŻ = 818 ± 8 (stat) ± 27 (syst) ± 19 (lumi) ± 12 (beam) pb,
where the four uncertainties arise from data statistics, experimental and theoretical systematic effects, the integrated luminosity and the LHC beam energy, giving a total relative uncertainty of 4.4%. The result is consistent with theoretical QCD calculations at next-to-next-to-leading order. A fiducial measurement corresponding to the experimental acceptance of the leptons is also presented
- âŠ