1,193 research outputs found
Structural and Spectroscopic Analysis of the Kinase Inhibitor Bosutinib and an Isomer of Bosutinib Binding to the Abl Tyrosine Kinase Domain
- Author
- A Vultur
- AGW Leslie
- B Nagar
- B Nagar
- BJ Druker
- CH Yun
- CH Yun
- CL Sawyers
- DH Boschelli
- DH Boschelli
- GD Demetri
- H Yamaguchi
- HM Kantarjian
- IT Suydam
- IT Suydam
- J Cools
- J Cortes
- J Stamos
- JE Cortes
- JM Golas
- JS Tokarski
- LJ Webb
- LM Toledo
- M Campone
- M Puttini
- M Talpaz
- MA Seeliger
- MA Seeliger
- MA Seeliger
- MA Young
- ME Gorre
- MW Karaman
- Nicholas M. Levinson
- NM Levinson
- NP Shah
- NP Shah
- P Emsley
- P le Coutre
- PD Adams
- Ramani Ramchandran
- S Redaelli
- S Roumiantsev
- SA Wells Jr
- SR Hubbard
- SS Andrews
- SS Andrews
- Steven G. Boxer
- T Schindler
- W Pao
- W Wang
- XJ Yin
- Y Shan
- Z Dauter
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2011
- Field of study
Chronic myeloid leukemia (CML) is caused by the kinase activity of the BCR-Abl fusion protein. The Abl inhibitors imatinib, nilotinib and dasatinib are currently used to treat CML, but resistance to these inhibitors is a significant clinical problem. The kinase inhibitor bosutinib has shown efficacy in clinical trials for imatinib-resistant CML, but its binding mode is unknown. We present the 2.4 Å structure of bosutinib bound to the kinase domain of Abl, which explains the inhibitor's activity against several imatinib-resistant mutants, and reveals that similar inhibitors that lack a nitrile moiety could be effective against the common T315I mutant. We also report that two distinct chemical compounds are currently being sold under the name “bosutinib”, and report spectroscopic and structural characterizations of both. We show that the fluorescence properties of these compounds allow inhibitor binding to be measured quantitatively, and that the infrared absorption of the nitrile group reveals a different electrostatic environment in the conserved ATP-binding sites of Abl and Src kinases. Exploiting such differences could lead to inhibitors with improved selectivity
Introduction to the Conceptualisation of Environmental Citizenship for Twenty-First-Century Education
- Author
- A Dobson
- A Dobson
- B Cao
- C Melo-Escrihuela
- D Ockwell
- E Hazelkorn
- E Wenger
- E Wenger
- E Wenger
- EA Kyza
- Environmental Evidence Australia
- J Barry
- J Huckle
- J Lave
- JA Du Pisani
- KG Tidball
- L Chawla
- L Johnson
- M Carlsson
- N Gunningham
- N Roczen
- OECD
- OECD Publishing
- PC Stern
- PD Sherer
- R Levinson
- R Schild
- S Gough
- SC Jagers
- T Dietz
- TM Schusler
- U Beck
- V Corral-Verdugo
- W Schulz
- WM Roth
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2020
- Field of study
The EU’s growth strategy (Europe 2020) and the European vision for green, circular and low-carbon economy in line with the EU 2050 (EU-roadmap 2050) give par- ticular attention to citizens’ participation and engagement and therefore to Environmental Citizenship. Environmental Citizenship has been an influential con- cept in many different arenas such as economy, policy, philosophy, corporation management and marketing, which could also be better exploited and established in the field of education. Environmental Citizenship is recognized as an important aspect in addressing global environmental problems such as climate change (Stern 2011; Ockwell et al. 2009) whilst providing support to pro-environmental organisa- tions and individuals, contributing also to public pressure for political action (sign- ing petitions, writing to politicians and newspapers). Many varied definitions of Environmental Citizenship can be found within the literature. Some of them are quite similar, and important overlaps can be observed; however, others can be quite different with contradictions in their philosophy and approach. According to Dobson (2010), Environmental Citizenship refers to pro-environmental behaviour, in public and in private, driven by a belief in fairness of the distribution of environmental goods, in participation and in the co-creation of sustainability policy. It is about the active participation of citizens in moving towards sustainability. Education and especially environmental discourses in science education have a lot to contribute in adopting and promoting Environmental Citizenship. However, the conceptualisation of Environmental Citizenship in educational context remains an imperative need. The under-explored (until now) potential for pro-environmental behaviour change through Environmental Citizenship should be further emphasised (Dobson 2010) and can contribute greatly to a more sustainable world.info:eu-repo/semantics/publishedVersio
Chinese and white Canadian satisfaction and compliance with physicians
- Author
- AR Green
- D Kurpas
- DA Taira
- E Krupat
- E Krupat
- EH Lin
- GB Hickson
- H Quan
- H Quan
- H Vuori
- HT Stelfox
- Hude Quan
- JL Campbell
- JL Hargraves
- JL Murray-Garcia
- JW Lee
- K Fiscella
- KC Tang
- KE Lasser
- L Shi
- Lawrence So
- M Seid
- MD Wong
- ME Jimenez-Corona
- MG Haviland
- MG Haviland
- NL Keating
- PD Cleary
- Q Ngo-Metzger
- Q Ngo-Metzger
- Richard Liu
- S Saha
- S Saha
- SA Flocke
- TP Lam
- W Levinson
- Publication venue
- BioMed Central
- Publication date
- 01/01/2007
- Field of study
BACKGROUND: Patient satisfaction has become an important indicator of primary care and healthcare system performance. Ethnic disparities in patient satisfaction and compliance with physician care have been studied in several countries. However, this issue has not received significant attention in Canada. The unique characteristics of the Canadian healthcare system and ethnic population make it worthwhile to examine this issue in this population. Therefore, we conducted a survey among Chinese and Whites in a Canadian city to determine their reported satisfaction, and perceptions of physicians. METHODS: The survey was conducted in English, Mandarin and Cantonese in 2005 among Chinese and White Canadians, 18 years of age or older, who had visited at least one physician in Canada. RESULTS: We analyzed 746 Chinese and 711 Whites in the general practitioner (GP) visit group and 485 Chinese and 637 Whites in the specialist visit group. A lower proportion of Chinese compared to Whites reported that they were very satisfied or satisfied with GP (73.7% vs. 92.8%) and specialist care (75.5% vs. 85.6%) and the differences between the two groups remained after adjustment for demographic variables and chronic conditions (risk adjusted OR: 0.70, 95%CI: 0.42–1.18 for the GP visit group and OR: 0.77, 95%CI: 0.48–1.23 for the specialist visit group). A similar proportion of Chinese and Whites reported that they always followed a physician's advice (59.4% vs. 59.6% for the GP visit group and 67.2% vs. 62.8% for the specialist visit group). Non-English speaking Chinese and recent arrivals in Canada were less likely to be satisfied with GPs than Chinese born in Canada [risk adjusted OR: 0.5, 95%CI: 0.3–0.9, 0.2 and 0.1–0.7, respectively]. CONCLUSION: Chinese Canadians reported lower satisfaction with physicians and perceived physicians slightly more negatively than White Canadians. Particularly, Chinese with limited English and short length of stay in Canada were less satisfied than Canadian born Chinese
Cross-national epidemiology of DSM-IV major depressive episode
- Author
- Aimee N Karam
- C Benjet
- Chiyi Hu
- CJ Murray
- D Kebede
- D Levinson
- Daphna Levinson
- David R Williams
- EJ Bromet
- Evelyn Bromet
- GE Simon
- Giovanni de Girolamo
- Herbert Matschinger
- HS Koplewicz
- Irving Hwang
- J Harkness
- J Spijker
- Jagdish Kaur
- JC Riley
- JE Wells
- Jean-Pierre Lépine
- JM Haro
- Jordi Alonso
- Jose Posada-Villa
- K Demyttenaere
- KM Wolter
- Koen Demyttenaere
- L Andrade
- Laura Helena Andrade
- LN Robins
- M Tomlinson
- M Von Korff
- Maria Carmen Viana
- Maria Elena Medina Mora
- Mark Oakley Browne
- MM Weissman
- Nancy A Sampson
- Noboru Iwata
- O Gureje
- O Gureje
- PD Ellis
- RC Kessler
- RC Kessler
- RC Kessler
- RC Kessler
- RC Kessler
- Research Triangle Institute
- RG Wilkinson
- Ron de Graaf
- Ronald C Kessler
- S Lee
- S Moussavi
- S Van de Velde
- SB Patten
- SM Chang
- Stanislav Kostyuchenko
- TB Üstün
- Publication venue
- BioMed Central
- Publication date
- 01/01/2011
- Field of study
Background: Major depression is one of the leading causes of disability worldwide, yet epidemiologic data are not available for many countries, particularly low- to middle-income countries. In this paper, we present data on the prevalence, impairment and demographic correlates of depression from 18 high and low-to middle-income countries in the World Mental Health Survey Initiative. Methods: Major depressive episodes (MDE) as defined by the Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DMS-IV) were evaluated in face-to-face interviews using the World Health Organization Composite International Diagnostic Interview (CIDI). Data from 18 countries were analyzed in this report (n = 89,037). All countries surveyed representative, population-based samples of adults. Results: The average lifetime and 12-month prevalence estimates of DSM-IV MDE were 14.6% and 5.5% in the ten high-income and 11.1% and 5.9% in the eight low- to middle-income countries. The average age of onset ascertained retrospectively was 25.7 in the high-income and 24.0 in low- to middle-income countries. Functional impairment was associated with recency of MDE. The female: male ratio was about 2: 1. In high-income countries, younger age was associated with higher 12-month prevalence; by contrast, in several low-to middle-income countries, older age was associated with greater likelihood of MDE. The strongest demographic correlate in high-income countries was being separated from a partner, and in low- to middle-income countries, was being divorced or widowed. Conclusions: MDE is a significant public-health concern across all regions of the world and is strongly linked to social conditions. Future research is needed to investigate the combination of demographic risk factors that are most strongly associated with MDE in the specific countries included in the WMH.(NIH/NIMH) United States National Institute of Mental Health[R01MH070884]John D. and Catherine T. MacArthur FoundationPfizer FoundationUSA Public Health Service[R13-MH066849]USA Public Health Service[R01-MH069864]USA Public Health Service[R01 DA016558](NIH) Fogarty International Center[FIRCA R03-TW006481]PAHO Pan American Health OrganizationEli Lilly & Company FoundationOrtho-McNeil Pharmaceutical, Inc.GlaxoSmithKlineSanofi-AventisBristol-Myers SquibbState of Brazil Research Foundation (FAPESP)[03/00204-3]Ministry of Social ProtectionEuropean Commission[QLG5-1999-01042]European Commission[SANCO 2004123]Piedmont Region (Italy)Fondo de Investigacion Sanitaria, Instituto de Salud Carlos III, Spain[FIS 00/0028]Spanish Ministerio de Ciencia y Tecnologia[SAF 2000-158-CE]Departament de Salut, Generalitat de Catalunya, SpainInstituto de Salud Carlos III[CIBER CB06/02/0046]Instituto de Salud Carlos III[RETICS RD06/0011 REM-TAP]Government of IndiaWHOMinistry of HealthIsrael National Institute for Health Policy and Health Services ResearchNational Insurance Institute of IsraelJapan Ministry of Health, Labour and Welfare[H13-Shogai-023]Japan Ministry of Health, Labour and Welfare[H14-Tokubetsu-026]Japan Ministry of Health, Labour and Welfare[H16-Kokoro-013]Lebanese Ministry of Public HealthWHO (Lebanon)(NIH) Fogarty International, anonymous private donations to IDRAAC, LebanonJanssen CilagEli LillyRocheNovartisNational Institute of Psychiatry Ramon de la Fuente[INPRFMDIES 4280]CNPq National Council on Science and Technology[CONACyT-G30544-H]PanAmerican Health Organization (PAHO)New Zealand Ministry of Health, Alcohol Advisory CouncilHealth Research Council(NIH/NIMH) USA National Institute of Mental Health[R01-MH059575](NIH/NIMH) USA National Institute of Mental Health[RO1-MH61905]National Institute of Drug AbuseSouth African Department of HealthUniversity of MichiganNational Institute of Mental Health (NIH/NIMH)[U01-MH60220]National Institute of Drug Abuse (NIDA)Substance Abuse and Mental Health Services Administration (SAMHSA)Robert Wood Johnson Foundation (RWJF)[044708]John W. Alden TrustsAnalysis Group Inc.Eli Lilly CompanyEPI-QJohnson & Johnson PharmaceuticalsOrtho-McNeil Janssen Scientific AffairsPfizer Inc.Shire USA, Inc
Search for the standard model Higgs boson at LEP
- Author
- Abbaneo D
- Abbaneo D
- Abbiendi G
- Abbiendi G
- Abdallah J
- Abreu P
- Achard P
- Adam W
- Adriani O
- Adzic P
- Affholderbach K
- Aguilar-Benitez M
- Ainsley C
- Akesson PF
- Albrecht T
- Alcaraz J
- Alderweireld T
- Alemanni G
- Alemany-Fernandez R
- Alexander G
- Allaby J
- Allison J
- Allmendinger T
- Allport PP
- Aloisio A
- Alviggi MG
- Amaldi U
- Amapane N
- Amaral P
- Amato S
- Anagnostou G
- Anashkin E
- Anderhub H
- Anderson KJ
- Andreazza A
- Andreev VP
- Andringa S
- Anjos N
- Anselmo F
- Antilogus P
- Antonelli A
- Antonelli M
- Apel WD
- Arcelli S
- Arefiev A
- Armstrong SR
- Arnoud Y
- Asai S
- Ask S
- Asman B
- Augustin JE
- Augustinus A
- Awunor O
- Axen D
- Azemoon T
- Aziz T
- Azuelos G
- Azzurri P
- Baarmand M
- Badaud F
- Bagliesi G
- Bagnaia P
- Bailey I
- Baillon P
- Bajo A
- Baksay G
- Baksay L
- Baldew SV
- Ballestrero A
- Bambade P
- Banerjee S
- Banerjee S
- Barate R
- Barate R
- Barberio E
- Barbier R
- Barczyk A
- Bardin D
- Barillere R
- Barker G
- Barklow T
- Barlow RJ
- Baroncelli A
- Bartalini P
- Basile M
- Batalova N
- Batley RJ
- Battaglia M
- Battiston R
- Baubillier M
- Bay A
- Becattini F
- Bechtle P
- Becker U
- Becks KH
- Begalli M
- Behner F
- Behnke T
- Behrmann A
- Bell KW
- Bell PJ
- Bella G
- Bellerive A
- Bellucci L
- Ben-Haim E
- Bencivenni G
- Benekos N
- Benelli G
- Benvenuti A
- Berat C
- Berbeco R
- Berdugo J
- Berges P
- Berggren M
- Berkelman K
- Berntzon L
- Bertrand D
- Bertucci B
- Besancon M
- Besson N
- Betev BL
- Bethke S
- Beuselinck R
- Biasini M
- Biebell O
- Biglietti M
- Biland A
- Binnie DM
- Blair GA
- Blaising JJ
- Bloch D
- Bloch-Devaux B
- Blom M
- Blondel A
- Bloodworth IJ
- Bluj M
- Blumenschein U
- Blyth SC
- Bobbink GJ
- Boccali T
- Bock P
- Boeriun O
- Bohm A
- Bohrer A
- Boix G
- Boldizsar L
- Bologna G
- Bonacorsi D
- Bonesini M
- Bonissent A
- Boonekamp M
- Booth CN
- Booth PSL
- Borean C
- Borgia B
- Borisov G
- Bossi F
- Botner O
- Boucrot J
- Bouhova-Thacker E
- Boumediene D
- Bouquet B
- Bourilkov D
- Bourquin M
- Boutemeur M
- Bowcock TJV
- Bowdery CK
- Boyko I
- Braccini S
- Bracko M
- Braibant S
- Brandt S
- Branson JG
- Bravo S
- Brenner R
- Brient JC
- Brigliadori L
- Brochu F
- Brodet E
- Brown RM
- Bruckman P
- Bruneliere R
- Brunet JM
- Buchmuller O
- Buesser K
- Bugge L
- Buijs A
- Burckhart HJ
- Burger JD
- Burger WJ
- Buschmann P
- Cai XD
- Callot O
- Calvi M
- Cameron W
- Campana R
- Campana S
- Camporesi T
- Canale V
- Capell M
- Capon G
- Carena F
- Carlino G
- Carnegie RK
- Caron B
- Carr J
- Cartacci A
- Carter AA
- Carter JR
- Cartwright S
- Casado MP
- Casaus J
- Castro N
- Cattaneo A
- Cavallari F
- Cavallo F
- Cavallo N
- Cavanaugh R
- Cecchi C
- Cerrada M
- Cerutti F
- Chamizo M
- Chang CY
- Chang YH
- Chapkin M
- Charlton DG
- Charpentier P
- Checchia P
- Chemarin M
- Chen A
- Chen G
- Chen GM
- Chen HF
- Chen HS
- Chiarella V
- Chiefari G
- Chierici R
- Chiliapnikov P
- Chmeissani M
- Chudoba J
- Chung SU
- Cieslik K
- Cifarelli L
- Cindolo F
- Ciulli V
- Clare I
- Clare R
- Clarke DP
- Clerbaux B
- Clifft RW
- Coignet G
- Colaleo A
- Colas P
- Coles J
- Colino N
- Collins P
- Combley F
- Contri R
- Cosme G
- Cossutti F
- Costa MJ
- Costantini S
- Cowan G
- Coyle P
- Cranmer K
- Crawley B
- Creanza D
- Crennell D
- Crespo JM
- Csilling A
- Cucciarelli S
- Cuevas J
- Cuffiani M
- Curtil C
- D'Hondt J
- da Silva T
- Da Silva W
- Dado S
- Dai TS
- Dallavalle GM
- Dallison S
- Dalmau J
- David A
- Davier M
- Davies G
- De Angelis A
- de Asmundis R
- De Boer W
- De Bonis I
- De Clercq C
- De Filippis N
- de Guevara PL
- de Jong R
- de la Cruz B
- De Lotto B
- De Maria N
- De Min A
- de Palma M
- de Paula L
- De Roeck A
- De Salvo A
- De Vivie de Regie JB
- De Wolf EA
- Debreczeni J
- Decamp D
- Deglon P
- Degre A
- Deiters K
- Della Ricca G
- della Volpe D
- Delmeire E
- Denes P
- DeNotaristefani F
- Desch K
- Dessagne S
- Dhamotharan S
- Di Ciaccio L
- Di Simone A
- Diemoz M
- Dienes B
- Dierckxsens M
- Dietl H
- Dionisi C
- Dissertori G
- Dittmar M
- Donkers M
- Doria A
- Dornan PJ
- Doroba K
- Dova MT
- Drees J
- Drevermann H
- Dris M
- Dubbert J
- Duchesneau D
- Duchovni E
- Duckeck G
- Duerdoth IP
- Duflot L
- Duinker P
- Ealet A
- Echenard B
- Edgecock TR
- Eigen G
- Ekelof T
- El Mamouni H
- Elfgren E
- Eline A
- Ellert M
- Ellis G
- Elsing M
- Engler A
- Eppling FJ
- Etzion E
- Ewers A
- Extermann P
- Fabbri F
- Fabbro B
- Falagan MA
- Falciano S
- Falvard A
- Fanourakis G
- Fassouliotis D
- Favara A
- Fay J
- Fayolle D
- Fedin O
- Feindt M
- Felcini M
- Feld L
- Ferguson DPS
- Ferguson T
- Fernandez E
- Fernandez J
- Fernandez-Bosman M
- Ferrari P
- Ferrer A
- Ferro F
- Fesefeldt H
- Fiandrini E
- Fiedler F
- Field JH
- Filthaut F
- Finch AJ
- Fisher PH
- Fisher W
- Fisk I
- Flagmeyer U
- Fleck I
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- Foeth H
- Fokitis E
- Forconi G
- Ford M
- Forty RW
- Foster F
- Fouchez D
- Frank M
- Freudenreich K
- Frey A
- Fulda-Quenzer F
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- Gagnon P
- Galaktionov Y
- Gandelman M
- Ganguli SN
- Ganis G
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- Garcia C
- Garcia-Abia P
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- Gary JW
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- Geweniger C
- Ghete VM
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- Giammanco A
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- Gokieli R
- Goldberg J
- Golob B
- Gomez-Ceballos G
- Goncalves P
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- Green MG
- Greening TC
- Grenier G
- Grimm O
- Grivaz JF
- Grosdidier G
- Gross E
- Gruenewald MW
- Grunhaus J
- Grupen C
- Gruwe M
- Grzelak K
- Guida M
- Gunther PO
- Gupta A
- Gupta VK
- Gurtu A
- Gutay LJ
- Guy J
- Haag C
- Haas D
- Hajdu C
- Hallgren A
- Hamacher K
- Hamann M
- Hamilton K
- Hanke P
- Hansen J
- Hansen JB
- Hansen JD
- Hansen JR
- Hansen PH
- Hanson GG
- Harder K
- Harel A
- Harin-Dirac M
- Harvey J
- Hatzifotiadou D
- Haug S
- Hauler F
- Hauschild M
- Hauschildt J
- Hawkes CM
- Hawkings R
- Hayes OJ
- He H
- Hebbeker T
- Hedberg V
- Heister A
- Hemingway RJ
- Henneche M
- Hensel C
- Hepp V
- Herr H
- Herten G
- Herve A
- Hess J
- Heuer RD
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- Hill JC
- Hill RD
- Hirschfelder J
- Hodgson PN
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- Holldorfer F
- Holmgren SO
- Holt PJ
- Holzner G
- Homer RJ
- Horvath D
- Hou SR
- Houlden MA
- Howard R
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- Huntemeyer P
- Hutchcroft DE
- Huttmann K
- Iaselli G
- Igo-Kemenes P
- Ishii K
- Jacholkowska A
- Jackson JN
- Jakobs K
- Janot P
- Jarlskog G
- Jarry P
- Jeans D
- Jeremie H
- Jezequel S
- Jin BN
- Jin S
- Johansson EK
- Johansson PD
- Jones LT
- Jones LW
- Jones RWL
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- Joram C
- Josa-Mutuberria I
- Jost B
- Jousset J
- Jovanovic P
- Jungermann L
- Junk TR
- Kachelhoffer T
- Kado M
- Kafer D
- Kanaya N
- Kanzaki J
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- Kellogg RG
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- Kittel W
- Kjaer NJ
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- Klier A
- Klimentov A
- Kluge EE
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- Kluth S
- Kneringer E
- Kobayashi T
- Kobel M
- Kokkinias P
- Komamiya S
- Konig AC
- Konstantinidis N
- Kopal M
- Kormos L
- Kourkoumelis C
- Koutsenko V
- Kouznetsov O
- Kowalewski RV
- Kraber M
- Kraemer RW
- Kramer T
- Krenz W
- Kress T
- Krieger P
- Krop D
- Kruger A
- Kruger K
- Krumstein Z
- Kucharczyk M
- Kuhn D
- Kunin A
- Kupper M
- Kyriakis A
- Lafferty GD
- Laktineh I
- Lamsa J
- Lancon E
- Landi G
- Landsman H
- Lanske D
- Laurelli P
- Layter JG
- Le Coultre P
- Le Goff JM
- Lebeau M
- Lebedev A
- Lebrun P
- Lecomte P
- Lecoq P
- Leder G
- Ledroit F
- Lee HJ
- Lees JP
- Lehto M
- Leibenguth G
- Leinonen L
- Leins A
- Leiste R
- Leitner R
- Lellouch D
- Lemaire MC
- Lemaitre V
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- Letts J
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- Levtchenko P
- Li C
- Liebig W
- Ligabue F
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- Liko D
- Lillich J
- Lin CH
- Lin J
- Lin WT
- Linde FL
- Lipniacka A
- Lista L
- Litke AM
- Liu ZA
- Lloyd SL
- Locci E
- Loebinger FK
- Lohmann W
- Longo E
- Loomis C
- Lopes JH
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- Lu J
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- Luci C
- Luckey D
- Ludwig J
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- Lustermann W
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- Lutz P
- Lynch JG
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- Ma WG
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- Macpherson A
- Mader W
- Maggi G
- Maggi M
- Malek A
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- Malgeri L
- Malinin A
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- Mana C
- Mandl F
- Mangeol D
- Manner W
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- Yamashita S
- Yang BZ
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- Yang HJ
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- Zachariadou K
- Zalewska A
- Zalewski P
- Zalite A
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- Zavrtanik D
- Zeitnitz C
- Zer-Zion D
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- Zhu GY
- Zhu RY
- Zhuang HL
- Zhuravlov V
- Zichichi A
- Ziegler T
- Zilizi G
- Zimin NI
- Zimmermann B
- Zintchenko A
- Zito G
- Zivkovic L
- Zobernig G
- Zoller M
- Zupan M
- Publication venue
- ELSEVIER SCIENCE BV
- Publication date
- 17/07/2003
- Field of study
Jet energy measurement with the ATLAS detector in proton-proton collisions at root s=7 TeV
- Author
- Aad G
- Abbott B
- Abdallah J
- Abdelalim AA
- Abdesselam A
- Abdinov O
- Abi B
- Abolins M
- Abramowicz H
- Abreu H
- Acerbi E
- Acharya BS
- Adams DL
- Addy TN
- Adelman J
- Aderholz M
- Adomeit S
- Adragna P
- Adye T
- Aefsky S
- Aguilar-Saavedra JA
- Aharrouche M
- Ahlen SP
- Ahles F
- Ahmad A
- Ahsan M
- Aielli G
- Akdogana T
- Akesson TPA
- Akimoto G
- Akimov AV
- Akiyama A
- Aktas A
- Alam MA
- Alam MS
- Albert J
- Albrand S
- Aleksa M
- Aleksandrov IN
- Alessandria F
- Alexa C
- Alexander G
- Alexandre G
- Alexopoulos T
- Alhroob M
- Aliev M
- Alimonti G
- Alison J
- Aliyev M
- Allport PP
- Allwood-Spiers SE
- Almenar CC
- Almond J
- Aloisio A
- Alon R
- Alonso A
- Alviggi MG
- Amako K
- Amaral P
- Amelung C
- Ammosov VV
- Amorim A
- Amoros G
- Amram N
- Anastopoulos C
- Ancu LS
- Andari N
- Andeen T
- Anders CF
- Anders G
- Anderson KJ
- Andreazza A
- Andrei V
- Andrieux M-L
- Anduaga XS
- Angerami A
- Anghinolfi F
- Anh TV
- Anjos N
- Annovi A
- Antonaki A
- Antonelli M
- Antonov A
- Antos J
- Anulli F
- Aoun S
- Apolle R
- Arabidze G
- Aracena I
- Arai Y
- Aranda CP
- Arce ATH
- Archambault JP
- Arfaoui S
- Arguin J-F
- Arik E
- Arik M
- Armbruster AJ
- Arnaez O
- Arnault C
- Artamonov A
- Artoni G
- Arutinov D
- Asai S
- Asfandiyarov R
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- Asman B
- Asner D
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- Assamagan K
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- Atoian G
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- Badescu E
- Bagnaia P
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- Bailey DC
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- Baker OK
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- Baroncelli A
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- Battistoni G
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- Beddall AJ
- Bedikian S
- Bednyakov VA
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- Bellina F
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- Benary O
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- Benchouk C
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- Benjamin DP
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- Boddy CR
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- Boldea V
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- Bona M
- Bondarenko VG
- Bondioli M
- Boonekamp M
- Boorman G
- Booth CN
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- Borer C
- Borisov A
- Borissov G
- Borjanovic I
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- Bos K
- Boscherini D
- Bosman M
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- Botterill D
- Bouchami J
- Boudreau J
- Bouhova-Thacker EV
- Bourdarios C
- Bousson N
- Boveia A
- Boyd J
- Boyko IR
- Bozhko NI
- Bozovic-Jelisavcic I
- Bracinik J
- Braem A
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- Brandenburg GW
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- Bratzler U
- Brau B
- Brau JE
- Braun HM
- Brelier B
- Bremer J
- Brenner R
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- Breton D
- Britton D
- Brochu FM
- Brock I
- Brock R
- Brodbeck TJ
- Brodet E
- Broggi F
- Bromberg C
- Brooijmans G
- Brooks WK
- Brown G
- Brown H
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- Bruneliere R
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- Bruni A
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- Bruschi M
- BScher V
- Buanes T
- Bucci F
- Buchanan J
- Buchanan NJ
- Buchholz P
- Buckingham RM
- Buckley AG
- Buda SI
- Budagov IA
- Budick B
- Bueso XP
- Bugge L
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- Bulekov O
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- Buttinger W
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- Caforio D
- Cakir IT
- Cakir O
- Calafiura P
- Calderini G
- Calfayan P
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- Caloba LP
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- Camilocci ES
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- Canepaa A
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- Capua M
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- Carter AA
- Carter JR
- Carvalho J
- Casadei D
- Casado MP
- Cascella M
- Caso C
- Castaneda-Miranda E
- Castanheira MTD
- Castillo LRF
- Castro NF
- Cataldi G
- Cataneo F
- Catinaccio A
- Catmore JR
- Cattai A
- Cattani G
- Caughron S
- Cauz D
- Cavalcanti TP
- Cavalleri P
- Cavalli D
- Cavalli-Sforza M
- Cavasinni V
- Ceradini F
- Cerqueira AS
- Cerri A
- Cerrito L
- Cerutti F
- Cetin SA
- Cevenini F
- Chafaq A
- Chakraborty D
- Chan K
- Chapleau B
- Chapman JD
- Chapman JW
- Chareyre E
- Charlton DG
- Chavda V
- Cheatham S
- Chekanov S
- Chekulaev SV
- Chelkov GA
- Chelstowska MA
- Chen C
- Chen H
- Chen S
- Chen T
- Chen X
- Cheng S
- Cheong ALF
- Cheplakov A
- Chepurnov VF
- Chernyatin V
- Cheu E
- Cheung SL
- Chevalier L
- Chiefari G
- Chikovani L
- Childers JT
- Chilingarov A
- Chiodini G
- Chizhov MV
- Choudalakis G
- Chouridou S
- Christidi IA
- Christov A
- Chromek-Burckhart D
- Chu ML
- Chudoba J
- Ciapetti G
- Ciba K
- Ciftci AK
- Ciftci R
- Cinca D
- Cindro V
- Ciobotaru MD
- Cioccaa C
- Ciocio A
- Cirilli M
- Citterio M
- Ciubancan M
- Clark A
- Clark PJ
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- Clement B
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- Clifft RW
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- Cobal M
- Coccaro A
- Cochran J
- Codina EP
- Coe P
- Cogan JG
- Coggeshall J
- Cogneras E
- Cojocaru CD
- Colas J
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- Collaboration ATLAS
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- Collins NJ
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- Collot J
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- Conidi MC
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- Constantinescu S
- Conta C
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- Corradi M
- Correia AMH
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- Cortes-Gonzalez A
- Cortiana G
- Costa G
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- Costin T
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- Cowden C
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- Crupi R
- Cuciuc C-M
- Curatolo M
- Curtis CJ
- Curull XE
- Cwetanski P
- Czirr H
- Czyczula Z
- D'Auria S
- D'Onofrio M
- D'Orazio A
- Da Costa JBG
- Da Costa JGPF
- Da Silva PVM
- Da Via C
- Dabrowski W
- Dai T
- Dallapiccola C
- Daly CH
- Dam M
- Damazio DO
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- Damiani DS
- Danielsson HO
- Dannheim D
- Dao V
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- Daum C
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- Davey W
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- Davison AR
- Davygora Y
- Dawe E
- Dawson I
- Dawson JW
- Daya-Ishmukhametova RK
- de Asmundis R
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- De Cecco S
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- De Jong P
- De la Hoz SG
- De la Taille C
- De la Torre H
- De Lima JGR
- De Lotto B
- De Mora L
- De Nooij L
- De Pedis D
- De Regie JBDV
- De Renstrom PAB
- De Salvo A
- De Sanctis U
- De Santo A
- De K
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- Zsenei A
- Zutshi V
- Zwalinski L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/03/2013
- Field of study
The jet energy scale and its systematic uncertainty are determined for jets measured with the ATLAS detector at the LHC in proton-proton collision data at a centre-of-mass energy of √s = 7TeV corresponding to an integrated luminosity of 38 pb-1. Jets are reconstructed with the anti-kt algorithm with distance parameters R=0. 4 or R=0. 6. Jet energy and angle corrections are determined from Monte Carlo simulations to calibrate jets with transverse momenta pT≥20 GeV and pseudorapidities {pipe}η{pipe}<4. 5. The jet energy systematic uncertainty is estimated using the single isolated hadron response measured in situ and in test-beams, exploiting the transverse momentum balance between central and forward jets in events with dijet topologies and studying systematic variations in Monte Carlo simulations. The jet energy uncertainty is less than 2. 5 % in the central calorimeter region ({pipe}η{pipe}<0. 8) for jets with 60≤pT<800 GeV, and is maximally 14 % for pT<30 GeV in the most forward region 3. 2≤{pipe}η{pipe}<4. 5. The jet energy is validated for jet transverse momenta up to 1 TeV to the level of a few percent using several in situ techniques by comparing a well-known reference such as the recoiling photon pT, the sum of the transverse momenta of tracks associated to the jet, or a system of low-pT jets recoiling against a high-pT jet. More sophisticated jet calibration schemes are presented based on calorimeter cell energy density weighting or hadronic properties of jets, aiming for an improved jet energy resolution and a reduced flavour dependence of the jet response. The systematic uncertainty of the jet energy determined from a combination of in situ techniques is consistent with the one derived from single hadron response measurements over a wide kinematic range. The nominal corrections and uncertainties are derived for isolated jets in an inclusive sample of high-pT jets. Special cases such as event topologies with close-by jets, or selections of samples with an enhanced content of jets originating from light quarks, heavy quarks or gluons are also discussed and the corresponding uncertainties are determined. © 2013 CERN for the benefit of the ATLAS collaboration
Measurement of the inclusive and dijet cross-sections of b-jets in pp collisions at sqrt(s) = 7 TeV with the ATLAS detector
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- Zwalinski L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 31/12/2010
- Field of study
The inclusive and dijet production cross-sections have been measured for jets
containing b-hadrons (b-jets) in proton-proton collisions at a centre-of-mass
energy of sqrt(s) = 7 TeV, using the ATLAS detector at the LHC. The
measurements use data corresponding to an integrated luminosity of 34 pb^-1.
The b-jets are identified using either a lifetime-based method, where secondary
decay vertices of b-hadrons in jets are reconstructed using information from
the tracking detectors, or a muon-based method where the presence of a muon is
used to identify semileptonic decays of b-hadrons inside jets. The inclusive
b-jet cross-section is measured as a function of transverse momentum in the
range 20 < pT < 400 GeV and rapidity in the range |y| < 2.1. The bbbar-dijet
cross-section is measured as a function of the dijet invariant mass in the
range 110 < m_jj < 760 GeV, the azimuthal angle difference between the two jets
and the angular variable chi in two dijet mass regions. The results are
compared with next-to-leading-order QCD predictions. Good agreement is observed
between the measured cross-sections and the predictions obtained using POWHEG +
Pythia. MC@NLO + Herwig shows good agreement with the measured bbbar-dijet
cross-section. However, it does not reproduce the measured inclusive
cross-section well, particularly for central b-jets with large transverse
momenta.Comment: 10 pages plus author list (21 pages total), 8 figures, 1 table, final
version published in European Physical Journal
Search for direct pair production of the top squark in all-hadronic final states in proton-proton collisions at s√=8 TeV with the ATLAS detector
- Author
- Aad G
- Abbott B
- Abdallah J
- Abdinov O
- Aben R
- Abi B
- Abolins M
- AbouZeid OS
- Abramowicz H
- Abreu H
- Abreu R
- Abulaiti Y
- Acharya BS
- Adamczyk L
- Adams DL
- Adelman J
- Adomeit S
- Adye T
- Agatonovic-Jovin T
- Aguilar-Saavedra JA
- Agustoni M
- Ahlen SP
- Ahmadov F
- Aielli G
- Akerstedt H
- Akesson TPA
- Akimoto G
- Akimov AV
- Alberghi GL
- Albert J
- Albrand S
- Alconada Verzini MJ
- Aleksa M
- Aleksandrov IN
- Alexa C
- Alexander G
- Alexandre G
- Alexopoulos T
- Alhroob M
- Alimonti G
- Alio L
- Alison J
- Allbrooke BMM
- Allison LJ
- Allport PP
- Almond J
- Aloisio A
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- Alonso F
- Alpigiani C
- Altheimer A
- Alviggi MG
- Amako K
- Amaral Coutinho Y
- Amelung C
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- Amor Dos Santos SP
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- Amram N
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- Zinonos Z
- Ziolkowski M
- Zobernig G
- Zoccoli A
- zur Nedden M
- Zurzolo G
- Zutshi V
- Zwalinski L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2014
- Field of study
The results of a search for direct pair production of the scalar partner to the top quark using an integrated luminosity of 20.1fb−1 of proton–proton collision data at √s = 8 TeV recorded with the ATLAS detector at the LHC are reported. The top squark is assumed to decay via t˜→tχ˜01 or t˜→ bχ˜±1 →bW(∗)χ˜01 , where χ˜01 (χ˜±1 ) denotes the lightest neutralino (chargino) in supersymmetric models. The search targets a fully-hadronic final state in events with four or more jets and large missing transverse momentum. No significant excess over the Standard Model background prediction is observed, and exclusion limits are reported in terms of the top squark and neutralino masses and as a function of the branching fraction of t˜ → tχ˜01 . For a branching fraction of 100%, top squark masses in the range 270–645 GeV are excluded for χ˜01 masses below 30 GeV. For a branching fraction of 50% to either t˜ → tχ˜01 or t˜ → bχ˜±1 , and assuming the χ˜±1 mass to be twice the χ˜01 mass, top squark masses in the range 250–550 GeV are excluded for χ˜01 masses below 60 GeV
Observation of associated near-side and away-side long-range correlations in √sNN=5.02 TeV proton-lead collisions with the ATLAS detector
- Author
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- Publication venue
- American Physical Society
- Publication date
- 01/01/2012
- Field of study
Two-particle correlations in relative azimuthal angle (Δϕ) and pseudorapidity (Δη) are measured in √sNN=5.02 TeV p+Pb collisions using the ATLAS detector at the LHC. The measurements are performed using approximately 1 μb-1 of data as a function of transverse momentum (pT) and the transverse energy (ΣETPb) summed over 3.1<η<4.9 in the direction of the Pb beam. The correlation function, constructed from charged particles, exhibits a long-range (2<|Δη|<5) “near-side” (Δϕ∼0) correlation that grows rapidly with increasing ΣETPb. A long-range “away-side” (Δϕ∼π) correlation, obtained by subtracting the expected contributions from recoiling dijets and other sources estimated using events with small ΣETPb, is found to match the near-side correlation in magnitude, shape (in Δη and Δϕ) and ΣETPb dependence. The resultant Δϕ correlation is approximately symmetric about π/2, and is consistent with a dominant cos2Δϕ modulation for all ΣETPb ranges and particle pT
Search for pair-produced long-lived neutral particles decaying to jets in the ATLAS hadronic calorimeter in ppcollisions at √s=8TeV
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- Youssef S
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- Zaidan R
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- Zanzi D
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- Zhemchugov A
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- Zibell A
- Zieminska D
- Zimine NI
- Zimmermann C
- Zimmermann R
- Zimmermann S
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- Zutshi V
- Zwalinski L
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2014
- Field of study
The ATLAS detector at the Large Hadron Collider at CERN is used to search for the decay of a scalar boson to a pair of long-lived particles, neutral under the Standard Model gauge group, in 20.3fb−1of data collected in proton–proton collisions at √s=8TeV. This search is sensitive to long-lived particles that decay to Standard Model particles producing jets at the outer edge of the ATLAS electromagnetic calorimeter or inside the hadronic calorimeter. No significant excess of events is observed. Limits are reported on the product of the scalar boson production cross section times branching ratio into long-lived neutral particles as a function of the proper lifetime of the particles. Limits are reported for boson masses from 100 GeVto 900 GeV, and a long-lived neutral particle mass from 10 GeVto 150 GeV
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