Abelian varieties isogenous to a power of an elliptic curve

Let $E$ be an elliptic curve over a field $k$. Let $R:= \text{End}\, E$. There is a functor $\mathscr{H}\!\!\mathit{om}_R(-,E)$ from the category of finitely presented torsion-free left $R$-modules to the category of abelian varieties isogenous to a power of $E$, and a functor $\text{Hom}(-,E)$ in the opposite direction. We prove necessary and sufficient conditions on $E$ for these functors to be equivalences of categories.Comment: 21 pages, comments welcom

Clinician perspectives on what constitutes good practice in community services for people with complex emotional needs: A qualitative thematic meta-synthesis

INTRODUCTION: The need to improve the quality of community mental health services for people with Complex Emotional Needs (CEN) (who may have a diagnosis of 'personality disorder') is recognised internationally and has become a renewed policy priority in England. Such improvement requires positive engagement from clinicians across the service system, and their perspectives on achieving good practice need to be understood. AIM: To synthesise qualitative evidence on clinician perspectives on what constitutes good practice, and what helps or prevents it being achieved, in community mental health services for people with CEN. METHODS: Six bibliographic databases were searched for studies published since 2003 and supplementary citation tracking was conducted. Studies that used any recognised qualitative method and reported clinician experiences and perspectives on community-based mental health services for adults with CEN were eligible for this review, including generic and specialist settings. Meta-synthesis was used to generate and synthesise over-arching themes across included studies. RESULTS: Twenty-nine papers were eligible for inclusion, most with samples given a 'personality disorder' diagnosis. Six over-arching themes were identified: 1. The use and misuse of diagnosis; 2. The patient journey into services: nowhere to go; 3. Therapeutic relationships: connection and distance; 4. The nature of treatment: not doing too much or too little; 5. Managing safety issues and crises: being measured and proactive; 6. Clinician and wider service needs: whose needs are they anyway? The overall quality of the evidence was moderate. DISCUSSION: Through summarising the literature on clinician perspectives on good practice for people with CEN, over-arching priorities were identified on which there appears to be substantial consensus. In their focus on needs such as for a long-term perspective on treatment journeys, high quality and consistent therapeutic relationships, and a balanced approach to safety, clinician priorities are mainly congruent with those found in studies on service user views. They also identify clinician needs that should be met for good care to be provided, including for supervision, joint working and organisational support

Superior Cathode of Sodium-Ion Batteries: Orthorhombic V₂O₅ Nanoparticles Generated in Nanoporous Carbon by Ambient Hydrolysis Deposition

We, for the first time, demonstrate that orthorhombic V₂O₅ can exhibit superior electrochemical performance in sodium ion batteries when uniformly coated inside nanoporous carbon. The encapsulated V₂O₅ shows a specific capacity as high as 276 mAh/g, while the whole nanocomposite exhibits a capacity of 170 mAh/g. The V₂O₅/C composite was fabricated by a novel ambient hydrolysis deposition that features sequential water vapor adsorption in nanoporous carbon, followed by a hydrolysis reaction, exclusively inside the nanopores. The unique structure of the nanocomposite significantly enhances the capacity as well as the rate performance of orthorhombic V₂O₅ where the composite retains a capacity of over 90 mAh/g at a current rate of 640 mA/g. Furthermore, by calculating, we also revealed that a large portion of the sodium-ion storage, particularly at high current rates, is due to the V₂O₅ pseudocapacitance.Keywords: Pseudocapacitance, Sodium-Ion Batteries, Orthorhombic V₂O₅, Ambient Hydrolysis Depositio

Implementation, adoption and perceptions of telemental health during the COVID-19 pandemic: a systematic review

BACKGROUND: Early in 2020, mental health services had to rapidly shift from face-to-face models of care to delivering the majority of treatments remotely (by video or phone call or occasionally messaging) due to the COVID-19 pandemic. This resulted in several challenges for staff and patients, but also in benefits such as convenience or increased access for people with impaired mobility or in rural areas. There is a need to understand the extent and impacts of telemental health implementation, and barriers and facilitators to its effective and acceptable use. This is relevant both to future emergency adoption of telemental health, and to debates on its future use in routine mental health care. OBJECTIVE: To investigate the adoption and impacts of telemental health approaches during the COVID-19 Pandemic, and facilitators and barriers to optimal implementation. METHODS: Four databases (PubMed, PsycINFO, CINAHL and Web of Science) were searched for primary research relating to remote working, mental health care, and the COVID-19 pandemic. Preprint servers were also searched. Results of studies were synthesised using framework synthesis. RESULTS: A total of 77 papers met our inclusion criteria. In most studies, the majority of contacts could be transferred to a remote form during the pandemic, and good acceptability to service users and clinicians tended to be reported, at least where the alternative to remote contacts was interrupting care. However, a range of impediments to dealing optimal care by this means were also identified. CONCLUSIONS: Implementation of telemental health allowed some continuing support to the majority of service users during the COVID-19 pandemic and has value in an emergency situation. However, not all service users can be reached by this means, and better evidence is now needed on long-term impacts on therapeutic relationships and quality of care, and on impacts on groups at risk of digital exclusion and how to mitigate these. CLINICALTRIAL

Implementation, Adoption, and Perceptions of Telemental Health During the COVID-19 Pandemic: Systematic Review

BACKGROUND: Early in 2020, mental health services had to rapidly shift from face-to-face models of care to delivering the majority of treatments remotely (by video or phone call or occasionally messaging) due to the COVID-19 pandemic. This resulted in several challenges for staff and patients, but also in benefits such as convenience or increased access for people with impaired mobility or in rural areas. There is a need to understand the extent and impacts of telemental health implementation, and barriers and facilitators to its effective and acceptable use. This is relevant both to future emergency adoption of telemental health and to debates on its future use in routine mental health care. OBJECTIVE: To investigate the adoption and impacts of telemental health approaches during the COVID-19 pandemic, and facilitators and barriers to optimal implementation. METHODS: Four databases (PubMed, PsycINFO, CINAHL, and Web of Science) were searched for primary research relating to remote working, mental health care, and the COVID-19 pandemic. Preprint servers were also searched. Results of studies were synthesized using framework synthesis. RESULTS: A total of 77 papers met our inclusion criteria. In most studies, the majority of contacts could be transferred to a remote form during the pandemic, and good acceptability to service users and clinicians tended to be reported, at least where the alternative to remote contacts was interrupting care. However, a range of impediments to dealing optimal care by this means were also identified. CONCLUSIONS: Implementation of telemental health allowed some continuing support to the majority of service users during the COVID-19 pandemic and has value in an emergency situation. However, not all service users can be reached by this means, and better evidence is now needed on long-term impacts on therapeutic relationships and quality of care, and on impacts on groups at risk of digital exclusion and how to mitigate these. TRIAL REGISTRATION: PROSPERO International prospective register of systematic reviews CRD42021211025; https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021211025

Advances in the treatment of prolactinomas

Prolactinomas account for approximately 40% of all pituitary adenomas and are an important cause of hypogonadism and infertility. The ultimate goal of therapy for prolactinomas is restoration or achievement of eugonadism through the normalization of hyperprolactinemia and control of tumor mass. Medical therapy with dopamine agonists is highly effective in the majority of cases and represents the mainstay of therapy. Recent data indicating successful withdrawal of these agents in a subset of patients challenge the previously held concept that medical therapy is a lifelong requirement. Complicated situations, such as those encountered in resistance to dopamine agonists, pregnancy, and giant or malignant prolactinomas, may require multimodal therapy involving surgery, radiotherapy, or both. Progress in elucidating the mechanisms underlying the pathogenesis of prolactinomas may enable future development of novel molecular therapies for treatment-resistant cases. This review provides a critical analysis of the efficacy and safety of the various modes of therapy available for the treatment of patients with prolactinomas with an emphasis on challenging situations, a discussion of the data regarding withdrawal of medical therapy, and a foreshadowing of novel approaches to therapy that may become available in the future

Superior cathode of sodium-ion batteries: orthorhombic V₂O₅ nanoparticles generated in nanoporous carbon by ambient hydrolysis deposition.

For the first time, we demonstrate that orthorhombic V2O5 can exhibit superior electrochemical performance in sodium ion batteries when uniformly coated inside nanoporous carbon. The encapsulated V2O5 shows a specific capacity as high as 276 mAh/g, while the whole nanocomposite exhibits a capacity of 170 mAh/g. The V2O5/C composite was fabricated by a novel ambient hydrolysis deposition that features sequential water vapor adsorption in nanoporous carbon, followed by a hydrolysis reaction, exclusively inside the nanopores. The unique structure of the nanocomposite significantly enhances the capacity as well as the rate performance of orthorhombic V2O5 where the composite retains a capacity of over 90 mAh/g at a current rate of 640 mA/g. Furthermore, by calculating, we also revealed that a large portion of the sodium-ion storage, particularly at high current rates, is due to the V2O5 pseudocapacitance

Superior cathode of sodium-ion batteries: orthorhombic V₂O₅ nanoparticles generated in nanoporous carbon by ambient hydrolysis deposition.

For the first time, we demonstrate that orthorhombic V2O5 can exhibit superior electrochemical performance in sodium ion batteries when uniformly coated inside nanoporous carbon. The encapsulated V2O5 shows a specific capacity as high as 276 mAh/g, while the whole nanocomposite exhibits a capacity of 170 mAh/g. The V2O5/C composite was fabricated by a novel ambient hydrolysis deposition that features sequential water vapor adsorption in nanoporous carbon, followed by a hydrolysis reaction, exclusively inside the nanopores. The unique structure of the nanocomposite significantly enhances the capacity as well as the rate performance of orthorhombic V2O5 where the composite retains a capacity of over 90 mAh/g at a current rate of 640 mA/g. Furthermore, by calculating, we also revealed that a large portion of the sodium-ion storage, particularly at high current rates, is due to the V2O5 pseudocapacitance

Implementation of telemental health services before COVID-19:Rapid umbrella review of systematic reviews

BACKGROUND: Telemental health care has been rapidly adopted for maintaining services during the COVID-19 pandemic, and a substantial interest is now being devoted in its future role. Service planning and policy making for recovery from the pandemic and beyond should draw on both COVID-19 experiences and the substantial research evidence accumulated before this pandemic. OBJECTIVE: We aim to conduct an umbrella review of systematic reviews available on the literature and evidence-based guidance on telemental health, including both qualitative and quantitative literature. METHODS: Three databases were searched between January 2010 and August 2020 for systematic reviews meeting the predefined criteria. The retrieved reviews were independently screened, and those meeting the inclusion criteria were synthesized and assessed for risk of bias. Narrative synthesis was used to report these findings. RESULTS: In total, 19 systematic reviews met the inclusion criteria. A total of 15 reviews examined clinical effectiveness, 8 reported on the aspects of telemental health implementation, 10 reported on acceptability to service users and clinicians, 2 reported on cost-effectiveness, and 1 reported on guidance. Most reviews were assessed to be of low quality. The findings suggested that video-based communication could be as effective and acceptable as face-to-face formats, at least in the short term. Evidence on the extent of digital exclusion and how it can be overcome and that on some significant contexts, such as children and young people’s services and inpatient settings, was found to be lacking. CONCLUSIONS: This umbrella review suggests that telemental health has the potential to be an effective and acceptable form of service delivery. However, we found limited evidence on the impact of its large-scale implementation across catchment areas. Combining previous evidence and COVID-19 experiences may allow realistic planning for the future implementation of telemental health