6,594 research outputs found

    Mathematical models. Oral questions

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    Parabolic problems with general Wentzell boundary conditions and diffusion on the boundary

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    We show a result of maximal regularity in spaces of H\"older continuous function, concerning linear parabolic systems, with dynamic or Wentzell boundary conditions, with an elliptic diffusion term on the boundary

    Classical solutions to quasilinear parabolic problems with dynamic boundary conditions

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    We study linear nonautonomous parabolic systems with dynamic boundary conditions. Next, we apply these results to show a theorem of local existence and uniqueness of a classical solution to a second order quasilinear system with nonlinear dynamic boundary conditions

    Identification of a convolution kernel in a control problem for the heat equation with a boundary memory term

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    We consider the evolution of the temperature uu in a material with thermal memory characterized by a time-dependent convolution kernel hh. The material occupies a bounded region Ω\Omega with a feedback device controlling the external temperature located on the boundary Γ\Gamma. Assuming both uu and hh unknown, we formulate an inverse control problem for an integrodifferential equation with a nonlinear and nonlocal boundary condition. Existence and uniqueness results of a solution to the inverse problem are proved

    Techno-organizational change and skill formation: Evidence from Italian manufacturing firms

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    This paper emphasizes the role of labour demand as a determinant of working skill formation. In particular, we study the relationship between techno-organizational innovation and skill formation from a labour demand perspective. In this respect, we investigate if activities aimed at increasing the international commitment and the technological and organizational change do have an effect on both the propensity of firms to train and on the intensity of training. On this purpose, by relying on a job-competition-like framework about the operation of the labour market in allocating skills, we first estimate which factors do affect the propensity of firms to invest in work-based training activities, and, secondly, we estimate if the same factors do also play a role in determining the degree of intensity of such a training activity. Relying on a new dataset on Italian manufacturing firms active over the period 2001-2006, we first estimate a probit model on the probability for a firm to train; then we employ a Heckman two-stage selection model on the share of trainees with which we can control for selectivity bias. Our results point to a positive and significant effect of both firms’ characteristics, like size, specialization and capital intensity, and firms' techno-organisational activities on both training incidence and on training intensity. A particularly significant role, in this respect, is played by the combination of process innovation and the adoption of new organizational practices.human capital, international commitment, labour demand, organizational change, skill, technological innovation, work-based training

    Up to date on the use of triptans for child and adolescent migraine: “the state of the art”

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    The introduction of triptans, in the early 1990s, has improved the therapy for acute migraine attack, offering a new quality of life for those patients who suffer from this disabling neurological disorder. Epidemiological data point out that about 10% of school–age children suffer from migraine, with a progressive increase in incidence and prevalence up to the threshold of adulthood. The increase in extent and prevalence of migraine from the years of growth stresses the importance of the application and adjustment of ad hoc therapeutic (either pharmacological or not) and diagnostic measures. Indeed, the peculiar neurobiological and psychological aspects which are typical of an “evolving” organism preclude the use, by simple “transposition” or “proportion”, of the knowledge acquired from adult–targeted studies. That requires the implementation of studies to analyze the specific responses of children and adolescents to the triptans. To date, the studies on such issues are absolutely insufficient to draw definitive conclusions and indications for the use of triptans for child and adolescent migraineurs

    The effect of placebo and neurophysiological involvements

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    Placebo and placebo effect are important issues related to the drug therapy for clinical and scientific meanings. The rates of placebo may get as many as 50% for analgesic drugs in headache. The high answer to placebo brings questions on pathophysiology of headache. Answers may offer a new strategy in the implementation of trials and new insight in neurophysiology of headache. Current knowledge on placebo and placebo effect will be analysed and dicussed looking for new direction in headache field
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