1,457 research outputs found
Protecting an Ecosystem Service: Approaches to Understanding and Mitigating Threats to Wild Insect Pollinators
- Author
- Publication venue
- 'Elsevier BV'
- Publication date
- 08/01/2016
- Field of study
MARK4 controls ischaemic heart failure through microtubule detyrosination.
- Author
- A Ramkumar
- A Szyk
- B Goldstein
- B Trinczek
- C Aillaud
- C Zhou
- CA Arce
- CJ Murray
- CY Chen
- CY Chen
- EH Kellogg
- F Bottanelli
- F Li
- G Drewes
- H Doerflinger
- H Shigematsu
- J Nieuwenhuis
- JL Anderson
- JN Cohn
- JR Teerlink
- M Ackers-Johnson
- M Baldrighi
- M Barisic
- M Clement
- M Packer
- M Schuldt
- N Wang
- P Chinnakkannu
- P Robison
- S Illenberger
- S Kuhns
- S Toldo
- VR Pell
- X Li
- Y Zouggari
- Publication venue
- Nature
- Publication date
- 26/05/2021
- Field of study
Myocardial infarction is a major cause of premature death in adults. Compromised cardiac function after myocardial infarction leads to chronic heart failure with systemic health complications and a high mortality rate1. Effective therapeutic strategies are needed to improve the recovery of cardiac function after myocardial infarction. More specifically, there is a major unmet need for a new class of drugs that can improve cardiomyocyte contractility, because inotropic therapies that are currently available have been associated with high morbidity and mortality in patients with systolic heart failure2,3 or have shown a very modest reduction of risk of heart failure4. Microtubule detyrosination is emerging as an important mechanism for the regulation of cardiomyocyte contractility5. Here we show that deficiency of microtubule-affinity regulating kinase 4 (MARK4) substantially limits the reduction in the left ventricular ejection fraction after acute myocardial infarction in mice, without affecting infarct size or cardiac remodelling. Mechanistically, we provide evidence that MARK4 regulates cardiomyocyte contractility by promoting phosphorylation of microtubule-associated protein 4 (MAP4), which facilitates the access of vasohibin 2 (VASH2)-a tubulin carboxypeptidase-to microtubules for the detyrosination of α-tubulin. Our results show how the detyrosination of microtubules in cardiomyocytes is finely tuned by MARK4 to regulate cardiac inotropy, and identify MARK4 as a promising therapeutic target for improving cardiac function after myocardial infarction.BHF fellowship grant (FS/14/28/30713), Issac Newton Trust Grant (18.40u), and Cambridge BHF Centre of Research Excellence grants (RE/13/6/30180 and RE/18/1/34212)
Stroke prevalence among the Spanish elderly: an analysis based on screening surveys
- Author
- A Bergareche
- A Di Carlo
- A Di Carlo
- A Reggio
- Alberto Bergareche
- AM Thorsen
- Ana de Arce
- Antonio Lobo
- BS Schoenberg
- C Paschalis
- C Paschalis
- DC Bergen
- DF Stroup
- E Levy
- F Bermejo-Pareja
- F Levi
- F Meneghini
- FJ Carod-Artal
- FĂ©lix Bermejo-Pareja
- G Orlandi
- J Bamford
- J Matias-Guiu
- Jaime DĂaz-GuzmĂĄn
- JesĂșs de Pedro-Cuesta
- JL del Barrio
- JL Marti-Vilalta
- JM Morales
- Jordi GascĂłn
- José Luis del Barrio
- JosĂ© MarĂa Manubens
- M Caicoya
- M Jimenez Muro
- M Prencipe
- MJ Barrado-Lanzarote
- MJ Medrano
- MJ Medrano Albero
- MJ Muro
- Pedro Saz
- Per Thorvaldsen
- R Bonita
- R Gabriel
- R Grieve
- Ramón Reñé
- Raquel Boix
- S Hatano
- S LĂłpez-Pousa
- WHO Monica Project
- WHO Monica Project
- Publication venue
- BioMed Central
- Publication date
- 01/01/2006
- Field of study
BACKGROUND: This study sought to describe stroke prevalence in Spanish elderly populations and compare it against that of other European countries. METHODS: We identified screening surveys -both published and unpublished- in Spanish populations, which fulfilled specific quality requirements and targeted prevalence of stroke in populations aged 70 years and over. Surveys covering seven geographically different populations with prevalence years in the period 1991â2002 were selected, and the respective authors were then asked to provide descriptions of the methodology and raw age-specific data by completing a questionnaire. In addition, five reported screening surveys in European populations furnished useful data for comparison purposes. Prevalence data were combined, using direct adjustment and logistic regression. RESULTS: The overall study population, resident in central and north-eastern Spain, totalled 10,647 persons and yielded 715 cases. Age-adjusted prevalences, using the European standard population, were 7.3% for men, 5.6% for women, and 6.4% for both sexes. Prevalence was significantly lower in women, OR 0.79 95% CI 0.68â0.93, increased with age, particularly among women, and displayed a threefold spatial variation with statistically significant differences. Prevalences were highest, 8.7%, in suburban, and lowest, 3.8%, in rural populations. Compared to pooled Spanish populations, statistically significant differences were seen in eight Italian populations, OR 1.39 95%CI (1.18â1.64), and in Kungsholmen, Sweden, OR 0.40 95%CI (0.27â0.58). CONCLUSION: Prevalence in central and north-eastern Spain is higher in males and in suburban areas, and displays a threefold geographic variation, with women constituting the majority of elderly stroke sufferers. Compared to reported European data, stroke prevalence in Spain can be said to be medium and presents similar age- and sex-specific traits
Expressions of Multiple Neuronal Dynamics during Sensorimotor Learning in the Motor Cortex of Behaving Monkeys
- Author
- A Aboukhalil
- A Karni
- AAG Mattar
- AP Georgopoulos
- C Ghez
- CH Shea
- CS Li
- DA Simon
- E Salinas
- E Todorov
- E Todorov
- Eilon Vaadia
- EJ Hwang
- EM Robertson
- F Arce
- F Arce
- F Gandolfo
- F Gandolfo
- G Caithness
- G Wulf
- Georges Chapouthier
- H Imamizu
- HA Cunningham
- Itai Novick
- J Francis
- J Izawa
- JL Emken
- JR Lackner
- JW Krakauer
- JW Krakauer
- JW Krakauer
- KA Thoroughman
- KA Thoroughman
- KA Thoroughman
- KM Goedert
- KM Newell
- KM Newell
- LA Pascual
- MA Smith
- N Malfait
- O Bock
- O Donchin
- O Donchin
- PM Bays
- R Paz
- R Paz
- R Shadmehr
- R Shadmehr
- R Shadmehr
- RA Scheidt
- RJ Nudo
- RL Sainburg
- S Commins
- S Fusi
- S Monsell
- SE Criscimagna-Hemminger
- SJ Goodbody
- T Brashers-Krug
- T Brashers-Krug
- T Poggio
- T Savion-Lemieux
- VS Huang
- VS Huang
- Y Mandelblat-Cerf
- Y Tamashita
- Yael Mandelblat-Cerf
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- 01/01/2011
- Field of study
Previous studies support the notion that sensorimotor learning involves multiple processes. We investigated the neuronal basis of these processes by recording single-unit activity in motor cortex of non-human primates (Macaca fascicularis), during adaptation to force-field perturbations. Perturbed trials (reaching to one direction) were practiced along with unperturbed trials (to other directions). The number of perturbed trials relative to the unperturbed ones was either low or high, in two separate practice schedules. Unsurprisingly, practice under high-rate resulted in faster learning with more pronounced generalization, as compared to the low-rate practice. However, generalization and retention of behavioral and neuronal effects following practice in high-rate were less stable; namely, the faster learning was forgotten faster. We examined two subgroups of cells and showed that, during learning, the changes in firing-rate in one subgroup depended on the number of practiced trials, but not on time. In contrast, changes in the second subgroup depended on time and practice; the changes in firing-rate, following the same number of perturbed trials, were larger under high-rate than low-rate learning. After learning, the neuronal changes gradually decayed. In the first subgroup, the decay pace did not depend on the practice rate, whereas in the second subgroup, the decay pace was greater following high-rate practice. This group shows neuronal representation that mirrors the behavioral performance, evolving faster but also decaying faster at learning under high-rate, as compared to low-rate. The results suggest that the stability of a new learned skill and its neuronal representation are affected by the acquisition schedule.United States-Israel Binational Science FoundationIsrael Science FoundationIda Baruch FundRosetrees Trus
Performance of CMS muon reconstruction in pp collision events at sqrt(s) = 7 TeV
- Author
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullin S
- Acosta D
- Acosta JG
- Acosta MV
- Adair A
- Adam N
- Adam W
- Adams MR
- Adams T
- Adiguzel A
- Adler V
- Adzic P
- Agostino L
- Agram JL
- Aguilar-Benitez M
- Aguilo E
- Ahmad M
- Ahmad WH
- Ahuja S
- Akchurin N
- Akgun B
- Akgun U
- Akin IV
- Alagoz E
- Albajar C
- Albayrak EA
- Albergo S
- Albrow M
- Alda Junior WL
- Alexander J
- Aliev T
- Almeida N
- Alver B
- Alverson G
- Alves GA
- Amapane N
- Amsler C
- Anagnostou G
- Anastassov A
- Anderson J
- Anderson M
- Andrea J
- Andreev V
- Andreev V
- Andreev Y
- Andrews W
- Anghel IM
- Anjos TS
- Antonelli L
- Antunes JR
- Antunovic Z
- Apanasevich L
- Apollinari G
- Appelt E
- Apresyan A
- Aranyi A
- Arce P
- Arcidiacono R
- Arenton MW
- Arfaei H
- Argiro S
- Arisaka K
- Arneodo M
- Arora S
- Asawatangtrakuldee C
- Asghar MI
- Askew A
- Assran Y
- Ata M
- Atac M
- Atramentov O
- Attikis A
- Auffray E
- Autermann C
- Auzinger G
- Avdeeva E
- Avery P
- Avetisyan A
- Azarkin M
- Azhgirey I
- Aziz T
- Azzi P
- Azzolini V
- Azzurri P
- Baarmand MM
- Babb J
- Bacchetta N
- Bachtis M
- Baden A
- Baeni L
- Baesso P
- Baffioni S
- Bagliesi G
- Bai Y
- Baillon P
- Bainbridge R
- Bakhshiansohi H
- Bakirci MN
- Bakken JA
- Balazs M
- Ball AH
- Ball G
- Ban Y
- Banerjee S
- Banerjee S
- Bansal S
- Banzuzi K
- Barbagli G
- Barberis E
- Barbone L
- Bardak C
- Barfuss AF
- Bargassa P
- Barge D
- Baringer P
- Barker A
- Barnes VE
- Barnett BA
- Barney D
- Barone L
- Barrett M
- Bartalini P
- Barth C
- Basegmez S
- Basso L
- Battilana C
- Baty C
- Bauer G
- Bauerdick LAT
- Baumgartel D
- Baur U
- Bayshev I
- Bazterra VE
- Bean A
- Beauceron S
- Beaudette F
- Beaupere N
- Bedjidian M
- Beernaert K
- Behrenhoff W
- Behrens U
- Belforte S
- Beliy N
- Belknap D
- Bell AJ
- Bell KW
- Bellan P
- Bellan R
- Bellato M
- Bellinger JN
- Belotelov I
- Belyaev A
- Belyaev A
- Benaglia A
- Bencze G
- Bendavid J
- Benedetti D
- Benelli G
- Benhabib L
- Beni N
- Benucci L
- Benussi L
- Benvenuti AC
- Beranek S
- Beretvas A
- Bergauer T
- Berger J
- Bergholz M
- Beri SB
- Bernardes CA
- Bernardini J
- Bernet C
- Berry D
- Berry E
- Berryhill J
- Bertl W
- Berzano U
- Besancon M
- Betchart B
- Bethani A
- Betts RR
- Beuselinck R
- Bhat PC
- Bhatnagar V
- Bhattacharya S
- Bhattacharya S
- Bhatti A
- Bialas W
- Bialkowska H
- Bian JG
- Bianchi G
- Bianchini L
- Bianco S
- Biasini M
- Biino C
- Bilei GM
- Bilin B
- Bilinskas MJ
- Bilki B
- Bilmis S
- Biselli A
- Bisello D
- Bitioukov S
- Blekman F
- Blobel V
- Bloch D
- Bloch I
- Bloch P
- Bloom K
- Bluj M
- Blumenfeld B
- Blyweert S
- Bobrovskyi S
- Boccali T
- Bocci A
- Bochenek J
- Bodek A
- Bodin D
- Boimska B
- Boldizsar L
- Bolla G
- Bolognesi S
- Bolton T
- Bonacorsi D
- Bonato A
- Bondu O
- Bontenackels M
- Boos E
- Bornheim A
- Borras K
- Borrello L
- Bortignon P
- Bortoletto D
- Bose S
- Bose T
- Bostock F
- Botta C
- Boudoul G
- Boulahouache C
- Boumediene D
- Bourilkov D
- Boutemeur M
- Boutle S
- Braibant-Giacomelli S
- Branca A
- Branson JG
- Breedon R
- Breto G
- Breuker H
- Brew C
- Brigliadori L
- Brigljevic V
- Brinkerhoff A
- Broccolo G
- Brochero Cifuentes JA
- Brom JM
- Brona G
- Brooke JJ
- Broutin C
- Brown RM
- Brownson E
- Brun H
- Bruno G
- Bryer AG
- Buchmann MA
- Buchmuller O
- Bunkowski K
- Bunn J
- Buontempo S
- Burgmeier A
- Burkett K
- Busson P
- Busza W
- Butler JN
- Butler PH
- Butt J
- Butz E
- Bylsma B
- Cabrera A
- Cabrillo IJ
- Caebergs T
- Cakir A
- Calabria C
- Calderon De La Barca Sanchez M
- Calderon A
- Cali IA
- Calligaris L
- Callner J
- Calvert B
- Calvo E
- Campagnari C
- Campbell A
- Camporesi T
- Capiluppi P
- Caponeri B
- Cappello G
- Cardaci M
- Carlin R
- Carlsmith D
- Carrillo Moreno S
- Carroll R
- Cartiglia N
- Carvalho W
- Casal B
- Casimiro Linares E
- Castaldi R
- Castello R
- Castilla-Valdez H
- Castro A
- Castro E
- Caudron J
- Caulfield M
- Cavallari F
- Cavallo FR
- Cavallo N
- Cavanaugh R
- Ceard L
- Ceballos GG
- Cepeda M
- Cerati GB
- Cerci DS
- Cerci S
- Cerizza G
- Cerminara G
- Cerrada M
- Chabert EC
- Chadwick M
- Chakaberia I
- Chamizo Llatas M
- Chan M
- Chang P
- Chang S
- Chang YH
- Chang YH
- Chang YW
- Chanon N
- Chao Y
- Charaf O
- Charlot C
- Chasco M
- Chasserat J
- Chatrchyan S
- Chatterjee A
- Chauhan S
- Checchia P
- Chen GM
- Chen HS
- Chen J
- Chen KF
- Chen KH
- Chen M
- Chen Y
- Chen Z
- Cherepanov V
- Chertok M
- Chetluru V
- Cheung HWK
- Chhibra SS
- Chierici R
- Chiochia V
- Chiorboli M
- Chlebana F
- Cho Y
- Choi M
- Choi S
- Choi Y
- Choi YK
- Chou JP
- Choudhary BC
- Choudhury RK
- Choudhury S
- Christiansen T
- Chuang SH
- Chung J
- Chung YS
- Chwalek T
- Ciesielski R
- Cihangir S
- Cimmino A
- Cipriano PMR
- Cirino G
- Cittolin S
- Ciulli V
- Civinini C
- Claes DR
- Clare R
- Clarida W
- Clement E
- Clerbaux B
- Cline D
- CMS Collaboration
- Cockerill DJA
- Codispoti G
- Colafranceschi S
- Colaleo A
- Cole JE
- Colino N
- Collard C
- Colling D
- Conetti S
- Contardo D
- Conte E
- Contreras-Campana C
- Contreras-Campana E
- Conway J
- Conway R
- Cooper SI
- Cooper W
- Cornelis T
- Correa Martins Junior M
- Cortezon EP
- Cossutti F
- Costa M
- Costa S
- Costantini S
- Coughlan JA
- Cousins R
- Covarelli R
- Cox B
- Cox PT
- Creanza D
- Cremaldi LM
- Cripps N
- Cuevas J
- Cuffiani M
- Cumalat JP
- Cuplov V
- Cure B
- Cushman P
- Cussans D
- Custodio A
- Cutajar M
- Cutts D
- Cwiok M
- Czellar S
- D'Agnolo RT
- D'Alessandro R
- D'Alfonso M
- D'Enterria D
- D'Hondt J
- Da Costa EM
- Daci N
- Dahmes B
- Dahms T
- Dallavalle GM
- Damgov J
- Damiao DD
- Dammann D
- Danielson T
- Das S
- Daskalakis G
- Dasu S
- Daubie E
- Dauncey P
- David A
- Davids M
- Davies G
- de Barbaro P
- De Benedetti A
- De Boer W
- de Cassagnac RG
- De Cosa A
- de Fatis TT
- De Filippis N
- De Gruttola M
- De Guio F
- De Jeneret JD
- De La Cruz B
- De La Cruz-Burelo E
- De Lentdecker G
- De Mattia M
- de Monchenault GH
- De Oliveira Martins C
- De Palma M
- De Roeck A
- de Troconiz JF
- De Visscher S
- De Wolf EA
- Deisher A
- Deiters K
- Dejardin M
- del Arbol PMR
- Del Re D
- Delaere C
- Delgado Peris A
- Deliomeroglu M
- Dell'Orso R
- Della Negra M
- Della Ricca G
- Demaria N
- Demina R
- Demortier L
- Denegri D
- Deniz M
- Depasse P
- Dermenev A
- Dero V
- Dhingra N
- Di Giovanni GP
- Di Guida S
- Di Marco E
- Di Matteo L
- Diamond B
- Dias FA
- Diemoz M
- Dierlamm A
- Dietz C
- Dietz-Laursonn E
- Diez Pardos C
- Dimitrov A
- Dinardo ME
- Dirkes G
- Dissertori G
- Dittmar M
- Djordjevic M
- Dobrzynski L
- Dobson M
- Dobur D
- Doesburg R
- Dogangun O
- Dolen J
- Dominguez Vazquez D
- Dominguez A
- Dominik W
- Don CKK
- Dorigo T
- Dorney B
- Doroba K
- Dozen C
- Draeger J
- Dragicevic M
- Dragoiu C
- Drell BR
- Dremin I
- Drouhin F
- Drozdetskiy A
- du Pree T
- Duarte Campderros J
- Duarte J
- Dubinin M
- Dudero PR
- Dudko L
- Duenser M
- Dugad S
- Duggan D
- Dumanoglu I
- Dupont-Sagorin N
- Duric S
- Duris J
- Durkin LS
- Duru F
- Dutta D
- Dutta S
- Dutta V
- Dzelalija M
- Eads M
- Eartly DP
- Eckerlin G
- Ecklund KM
- Eckstein D
- Edelhoff M
- Edelmaier CJ
- Eerola P
- Efron J
- Eggert N
- Ekmedzic M
- El Mamouni H
- Elgammal S
- Elliott-Peisert A
- Ellison J
- Elmer P
- Elvira VD
- Enderle H
- Engh D
- Eno SC
- Epshteyn V
- Erbacher R
- Erdmann M
- Erdmann W
- Erfle J
- Erhan S
- Ero J
- Erofeeva M
- Ershov A
- Esen S
- Eshaq Y
- Eskut E
- Etesami SM
- Eugster J
- Eusebi R
- Evangelou I
- Evans D
- Everaerts P
- Everett A
- Evstyukhin S
- Fabbri F
- Fabbri F
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- Fabozzi F
- Faccioli P
- Fahim A
- Falkiewicz A
- Fanelli C
- Fanfani A
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- Fantasia C
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- Fasanella D
- Fassi F
- Faure JL
- Favaro C
- Favart D
- Fay J
- Fedi G
- Fehling D
- Feindt M
- Felcini M
- Feld L
- Ferapontov A
- Ferencek D
- Ferguson T
- Ferguson W
- Fernandez Bedoya C
- Fernandez Menendez J
- Fernandez Perez Tomei TR
- Fernandez Ramos JP
- Fernandez M
- Ferrando A
- Ferri F
- Ferro C
- Field RD
- Finger M
- Finger M
- Fiore L
- Fiorendi S
- Fiori F
- Fisher M
- Fisk I
- Flacher H
- Flanagan W
- Flix J
- Florez C
- Flossdorf A
- Flowers K
- Flucke G
- Flugge G
- Foa L
- Focardi E
- Folgueras S
- Fonseca De Souza S
- Fontaine J-C
- Ford WT
- Forthomme L
- Foudas C
- Fouz MC
- Franci D
- Francis B
- Franzoni G
- Frazier R
- Freeman J
- Freudenreich K
- Friedl M
- Friis E
- Frisch B
- Frosali S
- Frueboes T
- Fruhwirth R
- Fu Y
- Fulcher J
- Funk W
- Furic IK
- Futyan D
- Gabathuler K
- Gabella W
- Gabusi M
- Gaddi A
- Galanti M
- Gallinaro M
- Gallo E
- Gamsizkan H
- Ganguly S
- Ganjour S
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- Garcia G
- Garcia-Abia P
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- Garrido RGR
- Gartner J
- Gary JW
- Gascon S
- Gasparini F
- Gataullin M
- Gaultney V
- Gauthier L
- Gavrilov V
- Gay APR
- Gaz A
- Gebbert U
- Geenen H
- Geffert P
- Geiser A
- Geisler M
- Gele D
- Genchev V
- Gennai S
- Georgiou G
- Geralis T
- Gerbaudo D
- Gerber CE
- Gershtein Y
- Gerwig H
- Geurts FJM
- Ghete VM
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- Giacomelli P
- Giammanco A
- Giassi A
- Gibbons LK
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- Godshalk A
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- Gokbulut G
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- Goldberg S
- Goldenzweig P
- Goldstein J
- Golf F
- Gollapinni S
- Golovtsov V
- Golubev N
- Golunov A
- Golutvin I
- Gomber B
- Gomez Moreno B
- Gomez G
- Gomez JA
- Goncharov M
- Gonzalez Caballero I
- Gonzalez Lopez O
- Gonzalez Sanchez J
- Gonzalez JS
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- Goodell J
- Gorbounov N
- Gorski M
- Gotra Y
- Gottschalk E
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- Gouskos L
- Gouzevitch M
- Govoni P
- Gowdy S
- Goy Lopez S
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- Gramenitski I
- Grandi C
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- Gregoire G
- Gregores EM
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- Grigelionis I
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- Grishin V
- Gritsan AV
- Grogg KS
- Gronberg J
- Grothe M
- Grundler U
- Grunewald M
- Gruschke J
- Guchait M
- Gude A
- Gueth A
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- Guiducci L
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- Gulmez E
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- Guo Y
- Guo ZJ
- Gupta R
- Guragain S
- Gurrola A
- Gurtu A
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- Gutsche O
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- Hackstein C
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- Hadley NJ
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- Haguenauer M
- Hahn KA
- Hajdu C
- Halkiadakis E
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- Hall-Wilton R
- Halyo V
- Hammad GH
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- Han J
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- Hanson G
- Harder K
- Harel A
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- Hatakeyama K
- Hatherell Z
- Hauk J
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- Xiao H
- Xie S
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- Yang F
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- Yang Y
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- Yazgan E
- Yelton J
- Yetkin T
- Yi K
- Yildirim E
- Yilmaz Y
- Yohay R
- Yoo HD
- Yoo J
- Yoon AS
- York A
- Yu I
- Yu SS
- Yumiceva F
- Yun JC
- Zabel J
- Zabi A
- Zablocki J
- Zaganidis N
- Zakaria M
- Zalewski P
- Zanetti M
- Zang J
- Zang SL
- Zarubin A
- Zatserklyaniy A
- Zeinali M
- Zeise M
- Zeuner WD
- Zeyrek M
- Zhang J
- Zhang Z
- Zheng Y
- Zhokin A
- Zhu B
- Zhu RY
- Zhukov V
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- Ziebarth EB
- Ziegler J
- Zielinski M
- Zito G
- Zoeller MH
- Zotto P
- Zou W
- Zumerle G
- Zuranski A
- Publication venue
- 'IOP Publishing'
- Publication date
- 01/01/2012
- Field of study
The performance of muon reconstruction, identification, and triggering in CMS
has been studied using 40 inverse picobarns of data collected in pp collisions
at sqrt(s) = 7 TeV at the LHC in 2010. A few benchmark sets of selection
criteria covering a wide range of physics analysis needs have been examined.
For all considered selections, the efficiency to reconstruct and identify a
muon with a transverse momentum pT larger than a few GeV is above 95% over the
whole region of pseudorapidity covered by the CMS muon system, abs(eta) < 2.4,
while the probability to misidentify a hadron as a muon is well below 1%. The
efficiency to trigger on single muons with pT above a few GeV is higher than
90% over the full eta range, and typically substantially better. The overall
momentum scale is measured to a precision of 0.2% with muons from Z decays. The
transverse momentum resolution varies from 1% to 6% depending on pseudorapidity
for muons with pT below 100 GeV and, using cosmic rays, it is shown to be
better than 10% in the central region up to pT = 1 TeV. Observed distributions
of all quantities are well reproduced by the Monte Carlo simulation.Comment: Replaced with published version. Added journal reference and DO
Search for new phenomena in final states with an energetic jet and large missing transverse momentum in pp collisions at â s = 8 TeV with the ATLAS detector
- Author
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- Abbott B
- Abbott DC
- Abeling K
- Abhayasinghe DK
- Abidi SH
- AbouZeid OS
- Abraham NL
- Abramowicz H
- Abreu H
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- Abulaiti Y
- Acharya BS
- Achkar B
- Adachi S
- Adam L
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- Zhulanov V
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- Zinonos Z
- Ziolkowski M
- Zivkovic L
- Zobernig G
- Zoccoli A
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- Zorbas TG
- Zou R
- Zu Theenhausen HM
- Zwalinski L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2015
- Field of study
Results of a search for new phenomena in final states with an energetic jet and large missing transverse momentum are reported. The search uses 20.3 fbâ1 of â s = 8 TeV data collected in 2012 with the ATLAS detector at the LHC. Events are required to have at least one jet with pT > 120 GeV and no leptons. Nine signal regions are considered with increasing missing transverse momentum requirements between Emiss T > 150 GeV and Emiss T > 700 GeV. Good agreement is observed between the number of events in data and Standard Model expectations. The results are translated into exclusion limits on models with either large extra spatial dimensions, pair production of weakly interacting dark matter candidates, or production of very light gravitinos in a gauge-mediated supersymmetric model. In addition, limits on the production of an invisibly decaying Higgs-like boson leading to similar topologies in the final state are presente
Optimization of fixation methods for observation of bacterial cell morphology and surface ultrastructures by atomic force microscopy
- Author
- A Roosjen
- A Touhami
- AD Meade
- AE Pelling
- AM Lomonosov
- AV Bolshakova
- AV Bolshakova
- C Suthipintawong
- D Alsteens
- F Gaboriaud
- FA Samatey
- FT Arce
- G Andre
- GD McEwen
- H Handa
- ID Auerbach
- J St-Laurent
- JA Kiernan
- JL Telford
- JWAM Celie
- K Namba
- K Sahu
- K Vekemans
- KD Young
- L Paavilainen
- LS Dorobantu
- M Jaschke
- M Micic
- M Moloney
- O Stukalov
- RW Dapson
- RWM Hoetelmans
- S Maki-Yonekura
- T Schmid
- TA Camesano
- TK Korhonen
- Tong Zhang
- Y Harada
- YG Kuznetsov
- Yuanqing Chao
- Publication venue
- Springer-Verlag
- Publication date
- 01/01/2011
- Field of study
Fixation ability of five common fixation solutions, including 2.5% glutaraldehyde, 10% formalin, 4% paraformaldehyde, methanol/acetone (1:1), and ethanol/acetic acid (3:1) were evaluated by using atomic force microscopy in the present study. Three model bacteria, i.e., Escherichia coli, Pseudomonas putida, and Bacillus subtilis were applied to observe the above fixation methods for the morphology preservation of bacterial cells and surface ultrastructures. All the fixation methods could effectively preserve cell morphology. However, for preserving bacterial surface ultrastructures, the methods applying aldehyde fixations performed much better than those using alcohols, since the alcohols could detach the surface filaments (i.e., flagella and pili) significantly. Based on the quantitative and qualitative assessments, the 2.5% glutaraldehyde was proposed as a promising fixation solution both for observing morphology of both bacterial cell and surface ultrastructures, while the methonal/acetone mixture was the worst fixation solution which may obtain unreliable results
Jet energy measurement with the ATLAS detector in proton-proton collisions at root s=7 TeV
- Author
- Aad G
- Abbott B
- Abdallah J
- Abdelalim AA
- Abdesselam A
- Abdinov O
- Abi B
- Abolins M
- Abramowicz H
- Abreu H
- Acerbi E
- Acharya BS
- Adams DL
- Addy TN
- Adelman J
- Aderholz M
- Adomeit S
- Adragna P
- Adye T
- Aefsky S
- Aguilar-Saavedra JA
- Aharrouche M
- Ahlen SP
- Ahles F
- Ahmad A
- Ahsan M
- Aielli G
- Akdogana T
- Akesson TPA
- Akimoto G
- Akimov AV
- Akiyama A
- Aktas A
- Alam MA
- Alam MS
- Albert J
- Albrand S
- Aleksa M
- Aleksandrov IN
- Alessandria F
- Alexa C
- Alexander G
- Alexandre G
- Alexopoulos T
- Alhroob M
- Aliev M
- Alimonti G
- Alison J
- Aliyev M
- Allport PP
- Allwood-Spiers SE
- Almenar CC
- Almond J
- Aloisio A
- Alon R
- Alonso A
- Alviggi MG
- Amako K
- Amaral P
- Amelung C
- Ammosov VV
- Amorim A
- Amoros G
- Amram N
- Anastopoulos C
- Ancu LS
- Andari N
- Andeen T
- Anders CF
- Anders G
- Anderson KJ
- Andreazza A
- Andrei V
- Andrieux M-L
- Anduaga XS
- Angerami A
- Anghinolfi F
- Anh TV
- Anjos N
- Annovi A
- Antonaki A
- Antonelli M
- Antonov A
- Antos J
- Anulli F
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- Apolle R
- Arabidze G
- Aracena I
- Arai Y
- Aranda CP
- Arce ATH
- Archambault JP
- Arfaoui S
- Arguin J-F
- Arik E
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- Arutinov D
- Asai S
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- Bai Y
- Bailey DC
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- Baker OK
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- Barisonzi M
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- Borisov A
- Borissov G
- Borjanovic I
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- Bos K
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- Boterenbrood H
- Botterill D
- Bouchami J
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- Bouhova-Thacker EV
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- Boyd J
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- Bozovic-Jelisavcic I
- Bracinik J
- Braem A
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- Brandenburg GW
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- Butin F
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- Butterworth JM
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- Camarri P
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- Camilocci ES
- Campana S
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- Canale V
- Canelli F
- Canepaa A
- Cantero J
- Capasso L
- Caprini I
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- Carter JR
- Carvalho J
- Casadei D
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- Castanheira MTD
- Castillo LRF
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- Zhemchugov A
- Zheng S
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- Zitoun R
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- Zwalinski L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/03/2013
- Field of study
The jet energy scale and its systematic uncertainty are determined for jets measured with the ATLAS detector at the LHC in proton-proton collision data at a centre-of-mass energy of âs = 7TeV corresponding to an integrated luminosity of 38 pb-1. Jets are reconstructed with the anti-kt algorithm with distance parameters R=0. 4 or R=0. 6. Jet energy and angle corrections are determined from Monte Carlo simulations to calibrate jets with transverse momenta pTâ„20 GeV and pseudorapidities {pipe}η{pipe}<4. 5. The jet energy systematic uncertainty is estimated using the single isolated hadron response measured in situ and in test-beams, exploiting the transverse momentum balance between central and forward jets in events with dijet topologies and studying systematic variations in Monte Carlo simulations. The jet energy uncertainty is less than 2. 5 % in the central calorimeter region ({pipe}η{pipe}<0. 8) for jets with 60â€pT<800 GeV, and is maximally 14 % for pT<30 GeV in the most forward region 3. 2â€{pipe}η{pipe}<4. 5. The jet energy is validated for jet transverse momenta up to 1 TeV to the level of a few percent using several in situ techniques by comparing a well-known reference such as the recoiling photon pT, the sum of the transverse momenta of tracks associated to the jet, or a system of low-pT jets recoiling against a high-pT jet. More sophisticated jet calibration schemes are presented based on calorimeter cell energy density weighting or hadronic properties of jets, aiming for an improved jet energy resolution and a reduced flavour dependence of the jet response. The systematic uncertainty of the jet energy determined from a combination of in situ techniques is consistent with the one derived from single hadron response measurements over a wide kinematic range. The nominal corrections and uncertainties are derived for isolated jets in an inclusive sample of high-pT jets. Special cases such as event topologies with close-by jets, or selections of samples with an enhanced content of jets originating from light quarks, heavy quarks or gluons are also discussed and the corresponding uncertainties are determined. © 2013 CERN for the benefit of the ATLAS collaboration
Performance of CMS muon reconstruction in pp collision events at sqrt(s) = 7 TeV
- Author
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- Weber H
- Weber HA
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- Weber M
- Wehrli L
- Weiler T
- Weinberg M
- Wendland L
- Weng J
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- Xiao H
- Xie S
- Xu M
- Yagil A
- Yalvac M
- Yang F
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- Yazgan E
- Yelton J
- Yetkin T
- Yi K
- Yildirim E
- Yilmaz Y
- Yohay R
- Yoo HD
- Yoo J
- Yoon AS
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- Yu I
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- Yumiceva F
- Yun JC
- Zabel J
- Zabi A
- Zablocki J
- Zaganidis N
- Zakaria M
- Zalewski P
- Zanetti M
- Zang J
- Zang SL
- Zarubin A
- Zatserklyaniy A
- Zeinali M
- Zeise M
- Zeuner WD
- Zeyrek M
- Zhang J
- Zhang Z
- Zheng Y
- Zhokin A
- Zhu B
- Zhu RY
- Zhukov V
- Zhukova V
- Ziebarth EB
- Ziegler J
- Zielinski M
- Zito G
- Zoeller MH
- Zotto P
- Zou W
- Zumerle G
- Zuranski A
- Publication venue
- 'IOP Publishing'
- Publication date
- 01/01/2012
- Field of study
The performance of muon reconstruction, identification, and triggering in CMS
has been studied using 40 inverse picobarns of data collected in pp collisions
at sqrt(s) = 7 TeV at the LHC in 2010. A few benchmark sets of selection
criteria covering a wide range of physics analysis needs have been examined.
For all considered selections, the efficiency to reconstruct and identify a
muon with a transverse momentum pT larger than a few GeV is above 95% over the
whole region of pseudorapidity covered by the CMS muon system, abs(eta) < 2.4,
while the probability to misidentify a hadron as a muon is well below 1%. The
efficiency to trigger on single muons with pT above a few GeV is higher than
90% over the full eta range, and typically substantially better. The overall
momentum scale is measured to a precision of 0.2% with muons from Z decays. The
transverse momentum resolution varies from 1% to 6% depending on pseudorapidity
for muons with pT below 100 GeV and, using cosmic rays, it is shown to be
better than 10% in the central region up to pT = 1 TeV. Observed distributions
of all quantities are well reproduced by the Monte Carlo simulation.Comment: Replaced with published version. Added journal reference and DO
Measurement of the inclusive and dijet cross-sections of b-jets in pp collisions at sqrt(s) = 7 TeV with the ATLAS detector
- Author
- Aad G
- Abbott B
- Abdallah J
- Abdelalim AA
- Abdesselam A
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- Abolins M
- Abramowicz H
- Abreu H
- Acerbi E
- Acharya BS
- Ackers M
- Adams DL
- Addy TN
- Adelman J
- Aderholz M
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- Aguilar-Saavedra JA
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- Ahlen SP
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- Alam MA
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- Aleksandrov IN
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- Alessandria F
- Alexa C
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- Alison J
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- Allport PP
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- Zieminska D
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- Ziolkowski M
- Zitoun R
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- Zwalinski L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 31/12/2010
- Field of study
The inclusive and dijet production cross-sections have been measured for jets
containing b-hadrons (b-jets) in proton-proton collisions at a centre-of-mass
energy of sqrt(s) = 7 TeV, using the ATLAS detector at the LHC. The
measurements use data corresponding to an integrated luminosity of 34 pb^-1.
The b-jets are identified using either a lifetime-based method, where secondary
decay vertices of b-hadrons in jets are reconstructed using information from
the tracking detectors, or a muon-based method where the presence of a muon is
used to identify semileptonic decays of b-hadrons inside jets. The inclusive
b-jet cross-section is measured as a function of transverse momentum in the
range 20 < pT < 400 GeV and rapidity in the range |y| < 2.1. The bbbar-dijet
cross-section is measured as a function of the dijet invariant mass in the
range 110 < m_jj < 760 GeV, the azimuthal angle difference between the two jets
and the angular variable chi in two dijet mass regions. The results are
compared with next-to-leading-order QCD predictions. Good agreement is observed
between the measured cross-sections and the predictions obtained using POWHEG +
Pythia. MC@NLO + Herwig shows good agreement with the measured bbbar-dijet
cross-section. However, it does not reproduce the measured inclusive
cross-section well, particularly for central b-jets with large transverse
momenta.Comment: 10 pages plus author list (21 pages total), 8 figures, 1 table, final
version published in European Physical Journal
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