Tumores óseos del pie

El manejo de los tumores óseos es difícil, debido a sus diferentes formas y comportamientos y a su baja incidencia. El pie no escapa a este axioma, ya que los tumores en esta región anatómica son particularmente infrecuentes y pueden mostrar un comportamiento clínico y radiológico diferente del que evidencian en otras regiones del esqueleto. Los autores revisan, en primer lugar, los aspectos generales de los tumores óseos del pie, considerando su epidemiología, el proceder diagnóstico y pronóstico y las opciones terapéuticas, para luego pasar a examinar las particularidades regionales e histológicas de estas neoplasias en relación con su tratamiento.The management of bone tumours is difficult, both because of their varying forms and behaviours and because of their low incidence. The foot is no exception to this axiom, as tumours in this particular anatomic region are particularly infrequent and may exhibit a clinical and radiological behaviour completely at variance to that in other skeletal regions. The authors first review the general aspects of the bobe tumours of the foot, considering their epidemiology, the diagnostic procedure and prognosis and the therapeutic options, and then examine the regional and histologic peculiaritiesof these neoplasms as related to their therapeutic management

EFFECT OF NEUROMUSCULAR RESISTANCE TRAINING ON THE PERFORMANCE OF 5-KM RUNNERS

The study aimed to identify the effect of a neuromuscular resistance training protocol (NRTP) on the performance of 5-km distance runners. This study included 18 male runners (age=29.3±3.2 years, fat percentage=11.3±2.6%, body height=1.77±.04 m, body mass=73.4±4.4 kg, time in 5 km=20.6±2.4 min, training years=4.3±0.7 years). First, volunteers were anthropometrically evaluated, and they performed one-repetition maximum (1RM) 45o leg press (LP) strength test. Second, they performed an incremental protocol in the 45o LP to acquire the electromyographic threshold. Third, they completed a 5-km time trial run (5 km basal). In the fourth session, they performed NRTP in LP. And fifth, the 5-km time trial run was performed at 30 min, 48 h, 96 h, and 144 h post the NRTP intervention. A significant decrease (p≤.05) was observed when baseline values were compared with post 30 min and post 48 h (p=.02 and p=.04, respectively). However, there were significant positive differences in performance (p=.04 for time) when baseline values and post 144 h were analyzed. Therefore, it is concluded that the NRTP can be used by 5-km distance runners to improve their performance with a break of one week between the intervention and test

Leishmania infection in bats from a non-endemic region of Leishmaniasis in Brazil

Leishmaniasis is a complex of zoonotic diseases caused by parasites of the genus Leishmania, which can develop in domestic as well as wild animals and humans throughout the world. Currently, this disease is spreading in rural and urban areas of non-endemic regions in Brazil. Recently, bats have gained epidemiological significance in leishmaniasis due to its close relationship with human settlements. In this study, we investigated the presence of Leishmania spp. DNA in blood samples from 448 bats belonging to four families representing 20 species that were captured in the Triangulo Mineiro and Alto Paranaiba areas of Minas Gerais State (non-endemic areas for leishmaniasis), Brazil. Leishmania spp. DNA was detected in 8.0% of the blood samples, 41.6% of which were Leishmania infantum, 38.9% Leishmania amazonensis and 19.4% Leishmania braziliensis. No positive correlation was found between Leishmania spp. and bat food source. The species with more infection rates were the insectivorous bats Eumops perotis; 22.2% (4/18) of which tested positive for Leishmania DNA. The presence of Leishmania in the bat blood samples, as observed in this study, represents epidemiological importance due to the absence of Leishmaniasis cases in the region. © Cambridge University Press 2017

Tratamiento de regeneración endodóntica en pulpa vital y necrótica, utilizando fibrina rica en plaquetas y Biodentine: reporte de caso

Endodontic regeneration is an inductive and reparative biological treatment indicated to replace cell damage at the level of the dentinopulp complex. The objective of this study is to report a case of Endodontic Regenerative Therapy, in young permanent first molars, in a 10-year-old patient, using platelet-rich fibrin and Biodentine, applying two different protocols for combined diagnoses of irreversible pulpitis and pulp necrosis. The patient attended consultation due to extensive carious lesions. Clinical and imaging evaluations (X-rays and Cone Beam) were performed. The protocol in the necrotic canal consisted of disinfection with a bi-antibiotic paste and placement of a second-generation autologous scaffold matrix, made of biodegradable platelet-rich fibrin which is also , biocompatible and therefore without risk of immune rejection. The protocol in the canals with irreversible pulpitis consisted in a complete pulpotomy and placement of Biodentine calcium silicate cement, a material considered as first choice for pulp-conserving treatments, with properties similar to dentin. Eight weeks after the end of the treatment, a clinical control was conducted revealing an asymptomatic chart and negative palpation without the presence of fistula or abscess. This result indicated regeneration of the pulp tissues and success of the applied protocols. Controls will be carried out at 6, 12 and 18 months. Conclusion: The application of endodontic regenerative treatments, as performed in this reported case, is a favorable and innovative option to preserve, restore or replace the dental pulp. In comparison with conventional treatments, this procedure allows to return pulp functionality, complete development of the root, thickening of the dentinal walls and closure of the apical foramen of young permanent teeth affected by pulp pathologies. It is important that regenerative therapies are publicized and applied by dental professionalsLa regeneración endodóntica es un tratamiento inductivo y reparativo con bases biológicas, indicado para reemplazar los daños celulares a nivel del complejo dentinopulpar. El objetivo de este estudio es reportar un caso de Terapia Regenerativa Endodóntica, en primeros molares permanentes jóvenes, en un paciente de 10 años, a través del uso de fibrina rica en plaquetas y Biodentine, se aplicaron dos protocolos diferentes por diagnósticos combinados de pulpitis irreversible y necrosis pulpar. El paciente acude a consulta por presentar lesiones cariosas extensas; se realizaron evaluaciones clínicas e imagenológicas (radiografías y Cone Beam), el protocolo en el conducto necrótico consistió en la desinfección con pasta biantibiótica y la colocación de una matriz de andamiaje autóloga de segunda generación, elaborada de fibrina rica en plaquetas que es biodegradable, biocompatible y no existe riesgo de rechazo inmunológico. El protocolo en los conductos con pulpitis irreversibles consistió en pulpotomía total y colocación de cemento de silicato de calcio Biodentine, el cual se considera el material de primera elección para los tratamientos conservadores de la pulpa, con propiedades similares a la dentina. A 8 semanas de finalizado el tratamiento se realizó control clínico y el paciente mostró un cuadro asintomático, palpación negativa sin presencia de fístula o absceso lo que podría indicar regeneración de los tejidos pulpares y éxito de los protocolos aplicados. Los siguientes controles se realizán a los 6, 12 y 18 meses. Conclusión: la aplicación de los tratamientos regenerativos endodónticos como se realizó en el caso reportado, es una opción favorable e innovadora para preservar, restaurar o sustituir la pulpa dental, que en comparación con los tratamientos convencionales nos permiten devolver la funcionalidad pulpar, finalizar el desarrollo radicular, engrosamiento de las paredes dentinales y cierre del foramen apical de dientes permanentes jóvenes que han sido afectados por patologías pulpares. Es importante que las terapias regenerativas sean divulgadas y aplicadas por los profesionale

Documento de consenso: importancia nutricional y metabólica de la leche

La leche de vaca es un alimento básico en la alimentación humana en todas las etapas de la vida. Su procesamiento industrial ha permitido el acceso generalizado a su consumo por parte de la población, lo que ha contribuido a mejorar notablemente su nivel de salud. Desde el punto de vista de su composición, la leche es un alimento completo y equilibrado, que proporciona un elevado contenido de nutrientes en relación con su contenido calórico, por lo que su consumo debe considerarse necesario desde la infancia a la tercera edad. Los beneficios de la leche de vaca no se limitan exclusivamente a su valor nutricional, sino que se extienden más allá y constituyen un factor de prevención en determinadas patologías afluentes como son la enfermedad cardiovascular, algunos tipos de cáncer, la hipertensión arterial o en patología ósea o dental. Puede contribuir también en la lucha frente al sobrepeso y la obesidad infantil. En los últimos años hemos asistido a un descenso preocupante en el consumo de leche entre la población española, condicionado al menos en parte por ideas equivocadas sobre su consumo y el de otros derivados lácteos. Este documento de consenso pretende revisar el estado actual de la cuestión en relación con los efectos del consumo de leche sobre la salud, al tiempo que hace una llamada a las instituciones y a las sociedades científicas para elaborar programas y campañas divulgativas sobre los beneficios del consumo de leche y derivados lácteos.Cow’s milk is a staple food for human consumption at all stages of life. Industrial processing has allowed widespread access to its consumption by the population, which has helped to significantly improve their health. From its composition point of view, milk is a complete and balanced food that provides high nutrient content in relation to its calorie content, so its consumption should be considered necessary from childhood to elderly. The benefits of cow’s milk are not limited to its nutritional value, but extend beyond and are a factor of prevention in certain non communicable pathologies as cardiovascular disease, some cancers, high blood pressure or bone or dental pathology. It can also help in the fight against childhood overweight and obesity. In recent years we have seen a worrying decline in milk consumption among the Spanish population, at least in part influenced by misconceptions about its consumption and of other dairy products. This consensus document aims to review the current state of the topic regarding the effects of milk consumption on health, while making a call to the institutions and scientific societies to develop programs and information campaigns about the benefits of milk and dairy products consumption

Search for direct production of charginos and neutralinos in events with three leptons and missing transverse momentum in √s = 7 TeV pp collisions with the ATLAS detector

A search for the direct production of charginos and neutralinos in final states with three electrons or muons and missing transverse momentum is presented. The analysis is based on 4.7 fb−1 of proton–proton collision data delivered by the Large Hadron Collider and recorded with the ATLAS detector. Observations are consistent with Standard Model expectations in three signal regions that are either depleted or enriched in Z-boson decays. Upper limits at 95% confidence level are set in R-parity conserving phenomenological minimal supersymmetric models and in simplified models, significantly extending previous results

Jet size dependence of single jet suppression in lead-lead collisions at sqrt(s(NN)) = 2.76 TeV with the ATLAS detector at the LHC

Measurements of inclusive jet suppression in heavy ion collisions at the LHC provide direct sensitivity to the physics of jet quenching. In a sample of lead-lead collisions at sqrt(s) = 2.76 TeV corresponding to an integrated luminosity of approximately 7 inverse microbarns, ATLAS has measured jets with a calorimeter over the pseudorapidity interval |eta| < 2.1 and over the transverse momentum range 38 < pT < 210 GeV. Jets were reconstructed using the anti-kt algorithm with values for the distance parameter that determines the nominal jet radius of R = 0.2, 0.3, 0.4 and 0.5. The centrality dependence of the jet yield is characterized by the jet "central-to-peripheral ratio," Rcp. Jet production is found to be suppressed by approximately a factor of two in the 10% most central collisions relative to peripheral collisions. Rcp varies smoothly with centrality as characterized by the number of participating nucleons. The observed suppression is only weakly dependent on jet radius and transverse momentum. These results provide the first direct measurement of inclusive jet suppression in heavy ion collisions and complement previous measurements of dijet transverse energy imbalance at the LHC.Comment: 15 pages plus author list (30 pages total), 8 figures, 2 tables, submitted to Physics Letters B. All figures including auxiliary figures are available at http://atlas.web.cern.ch/Atlas/GROUPS/PHYSICS/PAPERS/HION-2011-02

J-PLUS: The javalambre photometric local universe survey

ABSTRACT: TheJavalambrePhotometric Local UniverseSurvey (J-PLUS )isanongoing 12-band photometricopticalsurvey, observingthousands of squaredegrees of theNorthernHemispherefromthededicated JAST/T80 telescope at the Observatorio Astrofísico de Javalambre (OAJ). The T80Cam is a camera with a field of view of 2 deg2 mountedon a telescopewith a diameter of 83 cm, and isequippedwith a uniquesystem of filtersspanningtheentireopticalrange (3500–10 000 Å). Thisfiltersystemis a combination of broad-, medium-, and narrow-band filters, optimallydesigned to extracttherest-framespectralfeatures (the 3700–4000 Å Balmer break region, Hδ, Ca H+K, the G band, and the Mg b and Ca triplets) that are key to characterizingstellartypes and delivering a low-resolutionphotospectrumforeach pixel of theobservedsky. With a typicaldepth of AB ∼21.25 mag per band, thisfilter set thusallowsforanunbiased and accuratecharacterization of thestellarpopulation in our Galaxy, itprovidesanunprecedented 2D photospectralinformationforall resolved galaxies in the local Universe, as well as accuratephoto-z estimates (at the δ z/(1 + z)∼0.005–0.03 precisionlevel) formoderatelybright (up to r ∼ 20 mag) extragalacticsources. Whilesomenarrow-band filters are designedforthestudy of particular emissionfeatures ([O II]/λ3727, Hα/λ6563) up to z < 0.017, theyalsoprovidewell-definedwindowsfortheanalysis of otheremissionlines at higherredshifts. As a result, J-PLUS has thepotential to contribute to a widerange of fields in Astrophysics, both in thenearbyUniverse (MilkyWaystructure, globular clusters, 2D IFU-likestudies, stellarpopulations of nearby and moderate-redshiftgalaxies, clusters of galaxies) and at highredshifts (emission-line galaxies at z ≈ 0.77, 2.2, and 4.4, quasi-stellarobjects, etc.). Withthispaper, wereleasethefirst∼1000 deg2 of J-PLUS data, containingabout 4.3 millionstars and 3.0 milliongalaxies at r <  21mag. With a goal of 8500 deg2 forthe total J-PLUS footprint, thesenumbers are expected to rise to about 35 millionstars and 24 milliongalaxiesbytheend of thesurvey.Funding for the J-PLUS Project has been provided by the Governments of Spain and Aragón through the Fondo de Inversiones de Teruel, the Spanish Ministry of Economy and Competitiveness (MINECO; under grants AYA2017-86274-P, AYA2016-77846-P, AYA2016-77237-C3-1-P, AYA2015-66211-C2-1-P, AYA2015-66211-C2-2, AYA2012-30789, AGAUR grant SGR-661/2017, and ICTS-2009-14), and European FEDER funding (FCDD10-4E-867, FCDD13-4E-2685