Divergence-Free Adaptive Mesh Refinement for Magnetohydrodynamics

In this paper we present a full-fledged scheme for the second order accurate, divergence-free evolution of vector fields on an adaptive mesh refinement (AMR) hierarchy. We focus here on adaptive mesh MHD. The scheme is based on making a significant advance in the divergence-free reconstruction of vector fields. In that sense, it complements the earlier work of Balsara and Spicer (1999) where we discussed the divergence-free time-update of vector fields which satisfy Stoke's law type evolution equations. Our advance in divergence-free reconstruction of vector fields is such that it reduces to the total variation diminishing (TVD) property for one-dimensional evolution and yet goes beyond it in multiple dimensions. Divergence-free restriction is also discussed. An electric field correction strategy is presented for use on AMR meshes. The electric field correction strategy helps preserve the divergence-free evolution of the magnetic field even when the time steps are sub-cycled on refined meshes. The above-mentioned innovations have been implemented in Balsara's RIEMANN framework for parallel, self-adaptive computational astrophysics which supports both non-relativistic and relativistic MHD. Several rigorous, three dimensional AMR-MHD test problems with strong discontinuities have been run with the RIEMANN framework showing that the strategy works very well.Comment: J.C.P., figures of reduced qualit

Cavalier King Charles Spaniels with Chiari-like malformation and Syringomyelia have increased variability of spatio-temporal gait characteristics

Abstract Background Chiari-like malformation in the Cavalier King Charles Spaniel is a herniation of the cerebellum and brainstem into or through the foramen magnum. This condition predisposes to Syringomyelia; fluid filled syrinxes within the spinal cord. The resulting pathology in spinal cord and cerebellum create neuropathic pain and changes in gait. This study aims to quantify the changes in gait for Cavalier King Charles Spaniel with Chiari-like malformation and Syringomyelia. Methods We compared Cavalier King Charles Spaniel with Chiari-like malformation with (n = 9) and without (n = 8) Syringomyelia to Border Terriers (n = 8). Two video cameras and manual tracking was used to quantify gait parameters. Results and conclusions We found a significant increase in coefficient of variation for the spatio-temporal characteristics and ipsilateral distance between paws and a wider base of support in the thoracic limbs but not in the pelvic limbs for Cavalier King Charles Spaniels compared with the border terrier

Risk of Hospitalization for Chronic Hemodialysis Patients

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/98235/1/j.1547-5069.1992.tb00230.x.pd

Early alterations in the electrophysiological properties of rat spinal motoneurones following neonatal axotomy

Early in development, motoneurones are critically dependent on their target muscles for survival and differentiation. Previous studies have shown that neonatal axotomy causes massive motoneurone death and abnormal function in the surviving motoneurones. We have investigated the electrophysiological and morphological properties of motoneurones innervating the flexor tibialis anterior (TA) muscle during the first week after a neonatal axotomy, at a time when the motoneurones would be either in the process of degeneration or attempting to reinnervate their target muscles. We found that a large number (∼75%) of TA motoneurones died within 3 weeks after neonatal axotomy. Intracellular recordings revealed a marked increase in motoneurone excitability, as indicated by changes in passive and active membrane electrical properties. These changes were associated with a shift in the motoneurone firing pattern from a predominantly phasic pattern to a tonic pattern. Morphologically, the dendritic tree of the physiologically characterized axotomized cells was significantly reduced compared with age-matched normal motoneurones. These data demonstrate that motoneurone electrical properties are profoundly altered shortly after neonatal axotomy. In a subpopulation of the axotomized cells, abnormally high motoneurone excitability (input resistance significantly higher compared with control cells) was associated with a severe truncation of the dendritic arbor, suggesting that this excitability may represent an early electrophysiological correlate of motoneurone degeneration

Archaeomagnetic and rock magnetic study of six kilns from North Africa (Tunisia and Morocco)

International audienceNew full-vector archaeomagnetic data for North Africa recovered from the study of six kilns, five from Tunisia and one from Morocco, are presented. Archaeological and historical considerations, along with three radiocarbon dates, indicate that the age of the kilns ranges between the 9th and 15th centuries AD. Rock magnetic analyses showed that the principal magnetic carriers are magnetite and low Ti titanomagnetite, along with variable contributions of thermally stable maghemite and a high coercivity phase with low unblocking temperatures. The magnetic mineralogy of the studied material is thermally stable and behaves ideally during archaeointensity experiments. Stepwise alternating field demagnetization isolated a single, stable, characteristic remanence component with very well defined directions at both specimen and structure levels. Mean archaeointensities have been obtained from successful classical Thellier experiments conducted on between five and eight independent samples per kiln. Thermoremanent magnetization (TRM) anisotropy and cooling rate effects upon TRM intensity have been investigated. The results showed that these effects are low for four of the six studied kilns, with differences between the uncorrected and corrected means of less than 3 per cent. For the other two structures differences between the uncorrected and corrected mean site intensities are 4.4 per cent and 5.8 per cent. These results highlight the necessity for TRM anisotropy and cooling rate corrections in archaeomagnetic studies if accurate archaeointensities are to be obtained. The new results suggest that high intensities occurred in Northwest Africa during the 9th century. Although more data are clearly needed to define this period of high intensity, the results are in agreement with the available European archaeointensity data. Acomparison between the newdata, other available archaeomagnetic determinations in nearby locations, and palaeosecular variation (PSV) curves derived from the regional SCHA.DIF.3k and global ARCH3K.1 geomagnetic field models shows good agreement between the new data and directional results derived from the models. However, some differences are observed between geomagnetic field models intensity results and available archaeointensity data for the studied regions. This highlights the need for new data for unexplored regions such as North Africa. The new data presented here better constrains the evolution of the geomagnetic field during historical times in this region. They represent a new step towards the construction of a reference PSV curve for Northwest Africa. Once established, this curve will represent a new dating method for this region

Magnetic particle characterization in the Seine river system: Implications for the determination of natural versus anthropogenic input

International audience[1] This study presents an innovative application of well-established environmental magnetic proxy parameters on fluvial sediments, with the aim to trace geological and human-induced processes in the complex Seine river drainage system in northern France. We seek to identify environmental fingerprints of mechanical and chemical weathering processes, the regional distribution of the suspended material, and changes in the balance of natural input versus anthropogenic pollution. In order to reach these goals, we applied a combination of rock magnetic and advanced scanning electron microscopic techniques on a large number of sediment trap samples. Generally, we observe an increase in magnetic concentration coupled with a coarsening in magnetic grain size downstream of the Seine river system. Furthermore, the dominant magnetomineralogy changes from high-coercivity minerals upstream in more rural areas to magnetite-dominated assemblages downstream. Each river (segment) shows its specific trend line depending on regional initial input, weathering conditions, drainage area, and potential pollution sources. One major outcome of this study is the observed significant correlation between anthropogenic antimony-rich iron oxide particles and the magnetic concentration. This shows the potential of magnetic remanence measurements as proxy parameters for specific heavy metal pollution concentrations. Hence, the environmental magnetic study presented herein serves to identify major trends as well as local particularities and leads to quantitative analyses of the contributions of individual tributaries in the Seine river system. Components: 9513 words, 9 figures, 4 tables

Comparative mortality of hemodialysis patients at for-profit and not-for-profit dialysis facilities in the United States, 1998 to 2003: A retrospective analysis

<p>Abstract</p> <p>Background</p> <p>Concern lingers that dialysis therapy at for-profit (versus not-for-profit) hemodialysis facilities in the United States may be associated with higher mortality, even though 4 of every 5 contemporary dialysis patients receive therapy in such a setting.</p> <p>Methods</p> <p>Our primary objective was to compare the mortality hazards of patients initiating hemodialysis at for-profit and not-for-profit centers in the United States between 1998 and 2003. For-profit status of dialysis facilities was determined after subjects received 6 months of dialysis therapy, and mean follow-up was 1.7 years.</p> <p>Results</p> <p>Of the study population (<it>N </it>= 205,076), 79.9% were dialyzed in for-profit facilities after 6 months of dialysis therapy. Dialysis at for-profit facilities was associated with higher urea reduction ratios, hemoglobin levels (including levels above 12 and 13 g/dL [120 and 130 g/L]), epoetin doses, and use of intravenous iron, and less use of blood transfusions and lower proportions of patients on the transplant waiting-list (<it>P </it>< 0.05). Patients dialyzed at for-profit and at not-for-profit facilities had similar mortality risks (adjusted hazards ratio 1.02, 95% CI 0.99–1.06, <it>P </it>= 0.143).</p> <p>Conclusion</p> <p>While hemodialysis treatment at for-profit and not-for-profit dialysis facilities is associated with different patterns of clinical benchmark achievement, mortality rates are similar.</p

Long-term evolution of an Oligocene/Miocene maar lake from Otago, New Zealand

Foulden Maar is a highly resolved maar lake deposit from the South Island of New Zealand comprising laminated diatomite punctuated by numerous diatomaceous turbidites. Basaltic clasts found in debris flow deposits near the base of the cored sedimentary sequence yielded two new ⁴⁰Ar/³⁹Ar dates of 24.51 ± 0.24 and 23.38 ± 0.24 Ma (2σ). The younger date agrees within error with a previously published ⁴⁰Ar/³⁹Ar date of 23.17 ± 0.19 Ma from a basaltic dyke adjacent to the maar crater. The diatomite is inferred to have been deposited over several tens of thousands of years in the latest Oligocene/earliest Miocene, and may have been coeval with the period of rapid glaciation and subsequent deglaciation of Antarctica known as the Mi-1 event. Sediment magnetic properties and SEM measurements indicate that the magnetic signal is dominated by pseudo-single domain pyrrhotite. The most likely source of detrital pyrrhotite is schist country rock fragments from the inferred tephra ring created by the phreatomagmatic eruption that formed the maar. Variations in magnetic mineral concentration indicate a decrease in erosional input throughout the depositional period, suggesting long-term (tens of thousands of years) environmental change in New Zealand in the latest Oligocene/earliest Miocene

Source of oceanic magnetic anomalies and the geomagnetic polarity time scale

Marine magnetic anomalies provide the framework for the geomagnetic polarity timescale for the Late Jurassic to Recent (since 160 Ma). Magnetostratigraphic records confirm that the polarity reversal sequence interpreted from magnetic anomalies is complete to a resolution of better than 30 ky. In addition to this record of polarity reversals, magnetic anomalies also appear to preserve information on geomagnetic intensity fluctuations. The correspondence of coherent near-bottom anomaly variations with independent estimates of field intensity provides strong evidence that geomagnetic intensity modulates the magnetization of the ocean crust. Indeed, many short wavelength anomaly variations in sea-surface magnetic profiles over fast-spreading ridges are likely attributable to geomagnetic intensity variations. Although longer-term geomagnetic field behavior may also be reflected in anomaly amplitudes, documenting such a signal requires a better understanding of time-dependent changes in the magnetic source (e.g., from low-temperature alteration) that may also affect magnetic anomalies. The extrusive layer, with an average remanence of ∼ 5 A m−1, is the largest contributor to magnetic anomalies. However, enhanced sampling of oceanic gabbros (average remanence ∼ 1 A m−1) and, to a lesser extent, dikes (average remanence ∼ 2 A m−1) reveals that these deeper (and thicker) layers likely generate anomalies comparable to those from the lavas. Lava accumulation at intermediate- and fast-spreading ridges typically occurs over a narrow (1–3 km) region and dike emplacement is even more narrowly confined, resulting in a relatively high fidelity record of geomagnetic field behavior. The slow cooling of the gabbroic layer, however, results in gently dipping polarity boundaries that significantly affect the skewness of the resulting anomalies, which is also a sensitive measure of net rotations of the source layer(s). The magnetizations of the dikes and gabbros are characterized by high stability and are not expected to significantly change with time, although there are insufficient data to confirm this. The lavas, however, typically show evidence of low-temperature alteration, which has been long regarded as a process that progressively reduces the magnetization (and degrades the geomagnetic signal) in the extrusive layer and reduces the amplitude of magnetic anomalies. Sufficient data have become available to examine this conventional wisdom. There is a substantial (∼ 4x) reduction in magnetization from on-axis samples to immediately off-axis drillsites (∼ 0.5 My), but little further change in half-dozen or so deep crustal sites to ∼ 160 Ma. High paleointensity that characterizes the last few thousand years may contribute significantly to the high on-axis magnetization. The task of evaluating changes in remanence of the extrusive layer is made more difficult by substantial cooling-rate-dependent changes in magnetic properties and the systematic variation in remanence with iron content (magnetic telechemistry). The commonly cited magnetic anomaly amplitude envelope is in fact not systematically observed – the Central Anomaly is elevated at slow-spreading ridges but is not as prominent at faster spreading rates. Nonetheless, magnetic anomaly amplitudes are consistent with magnetization change is poorly constrained. Direct determinations of the degree of low-temperature oxidation reveal the presence of highly oxidized titanomagnetite in samples less than 1 My old, suggesting a short (∼ 105 years) time constant though the effects of low-temperature oxidation are quite heterogeneous. While low-temperature oxidation does have some affect on lava magnetization and anomaly amplitudes, there is increasing evidence that marine magnetic anomalies are capable of recording a broad spectrum of geomagnetic field behavior, ranging from millennial-scale paleointensity variations to polarity reversals to apparent polar wander to, more speculatively, long-term changes in average field strength. Several emerging tools and approaches – autonomous vehicles, oriented samples, absolute paleointensity of near-ridge lavas, and measurements of the vector anomalous field – are therefore likely to significantly advance our understanding of the geomagnetic signal recorded in the oceanic crust, as well as our ability to utilize this information in addressing outstanding problems in crustal accretion processes