1,185 research outputs found
Expanding the clinical phenotype in patients with disease causing variants associated with atypical Usher syndrome
- Author
- Publication venue
- TAYLOR & FRANCIS INC
- Publication date
- 01/01/2021
- Field of study
Atypical Usher syndrome (USH) is poorly defined with a broad clinical spectrum. Here, we characterize the clinical phenotype of disease caused by variants in CEP78, CEP250, ARSG, and ABHD12.
Chart review evaluating demographic, clinical, imaging, and genetic findings of 19 patients from 18 families with a clinical diagnosis of retinal disease and confirmed disease-causing variants in CEP78, CEP250, ARSG, or ABHD12.
CEP78-related disease included sensorineural hearing loss (SNHL) in 6/7 patients and demonstrated a broad phenotypic spectrum including: vascular attenuation, pallor of the optic disc, intraretinal pigment, retinal pigment epithelium mottling, areas of mid-peripheral hypo-autofluorescence, outer retinal atrophy, mild pigmentary changes in the macula, foveal hypo-autofluorescence, and granularity of the ellipsoid zone. Nonsense and frameshift variants in CEP250 showed mild retinal disease with progressive, non-congenital SNHL. ARSG variants resulted in a characteristic pericentral pattern of hypo-autofluorescence with one patient reporting non-congenital SNHL. ABHD12-related disease showed rod-cone dystrophy with macular involvement, early and severe decreased best corrected visual acuity, and non-congenital SNHL ranging from unreported to severe.
This study serves to expand the clinical phenotypes of atypical USH. Given the variable findings, atypical USH should be considered in patients with peripheral and macular retinal disease even without the typical RP phenotype especially when SNHL is noted. Additionally, genetic screening may be useful in patients who have clinical symptoms and retinal findings even in the absence of known SNHL given the variability of atypical USH
Directing cell therapy to anatomic target sites in vivo with magnetic resonance targeting
- Author
- A Chanu
- A Sorensen
- AS Arbab
- B Burke
- BA Syed
- BB Yellen
- BG Kim
- D Surder
- DA Beauregard
- E Garbayo
- ES Nakasone
- J Bartholeyns
- J Bartoleyns
- J Magga
- J Riegler
- J Riegler
- K Setsompop
- KC Biju
- L Engell-Noerregaard
- LE Kandalaft
- M De Palma
- M Muthana
- M Muthana
- M Muthana
- M Studeny
- MH Kershaw
- MM Pike
- N Landazuri
- PG Kyrtatos
- RD Leek
- RT Branca
- S Martel
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 18/08/2015
- Field of study
Cell-based therapy exploits modified human cells to treat diseases but its targeted application
in specific tissues, particularly those lying deep in the body where direct injection is not
possible, has been problematic. Here we use a magnetic resonance imaging (MRI) system to
direct macrophages carrying an oncolytic virus, Seprehvir, into primary and metastatic tumour
sites in mice. To achieve this, we magnetically label macrophages with super-paramagnetic
iron oxide nanoparticles and apply pulsed magnetic field gradients in the direction of the
tumour sites. Magnetic resonance targeting guides macrophages from the bloodstream into
tumours, resulting in increased tumour macrophage infiltration and reduction in tumour
burden and metastasis. Our study indicates that clinical MRI scanners can not only track the
location of magnetically labelled cells but also have the potential to steer them into one or
more target tissues
Formyl Peptide Receptor as a Novel Therapeutic Target for Anxiety-Related Disorders
- Author
- A Alam
- A Strohle
- AC Carpenter
- AK Sato
- AL Stenfeldt
- BA Babbin
- C Gemperle
- C Marquez
- C Touma
- CA Janeway Jr
- CC Wentworth
- CC Wentworth
- CK Derian
- D El Kebir
- D Yang
- D Yang
- DA Christakis
- DE Ganella
- E Krump
- Elisabetta Panza
- F Cattaneo
- F Miceli
- F Sallusto
- FA Costa-Pinto
- FN Gavins
- FN Gavins
- Fulvio D'Acquisto
- G De Palma
- G Taglialatela
- Giuseppa Piras
- GT Condo
- H Lim
- H Mou
- IA Olsson
- IJ Santos-Soto
- Irene Gallo
- JA Foster
- Jeffrey W. Dalley
- JF Cryan
- JF Cryan
- JL Barr
- JL Gao
- JL Leasure
- JP Onnela
- JW Jahng
- K Chen
- K Chen
- KL McIlwain
- KM Neufeld
- L Spurr
- LM Sutton
- Lorenza Rattazzi
- M Antunes
- M Aoki
- M Bourin
- M Bourin
- M Keitoku
- M Perretti
- M Saigo
- MA Panaro
- Mauro Perretti
- MG Gareau
- MJ Molloy
- MJ Rane
- MM van Gaalen
- N Benaroya-Milshtein
- N Dufton
- N Dufton
- P Anton
- Q Wang
- Q Zhang
- R Diaz Heijtz
- R Luisi
- R Medzhitov
- RD Ye
- RM Deacon
- RM Deacon
- RM Deacon
- RN Walsh
- RS Kasai
- S Fediuc
- S Ihara
- S Kedia
- S Park
- S Pellow
- S Riviere
- SB Su
- SC Heo
- SD Liberles
- SD Munger
- SN Cooray
- T Sato
- Thomas Gobbetti
- Tiziana Rubino
- TJ Schoenfeld
- V Marashi
- Y De
- YH Cui
- YH Cui
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- 17/12/2014
- Field of study
Formyl peptide receptors (FPR) belong to a family of sensors of the immune system that detect microbe-associated molecules and inform various cellular and sensorial mechanisms to the presence of pathogens in the host. Here we demonstrate that Fpr2/3-deficient mice show a distinct profile of behaviour characterised by reduced anxiety in the marble burying and light-dark box paradigms, increased exploratory behaviour in an open-field, together with superior performance on a novel object recognition test. Pharmacological blockade with a formyl peptide receptor antagonist, Boc2, in wild type mice reproduced most of the behavioural changes observed in the Fpr2/3(-/-) mice, including a significant improvement in novel object discrimination and reduced anxiety in a light/dark shuttle test. These effects were associated with reduced FPR signalling in the gut as shown by the significant reduction in the levels of p-p38. Collectively, these findings suggest that homeostatic FPR signalling exerts a modulatory effect on anxiety-like behaviours. These findings thus suggest that therapies targeting FPRs may be a novel approach to ameliorate behavioural abnormalities present in neuropsychiatric disorders at the cognitive-emotional interface
Optimization of Ti/Ta2O5âSnO2 electrodes and reaction parameters for electrocatalytic oxidation of methylene blue
- Author
- A El-Ghenymy
- A Ghonim
- B Adams
- BK Gu
- C Cameselle
- C Comninellis
- C Comninellis
- C MartĂnez-Hutile
- D Pletcher
- D Rajkumar
- D Shao
- EP Rivero
- H Toyosaki
- J Fan
- J Kim
- J Kong
- JM Aquino
- John Graves
- L Andrade
- L Andrade
- L GarcĂa-Cruz
- L Silva Da
- L Xu
- L Yue
- M Beck
- M El-Shahawi
- M Shestakova
- M Shestakova
- M Zhou
- Maciek Sitarz
- Marina Shestakova
- Mika Sillanpää
- MM Barsan
- N Greenwood
- R KĂśtz
- RE Palma-Goyes
- S Menolasina
- S Stucki
- S Trasatti
- T Gan
- U Pagga
- V LĂłpez-Grimau
- Y Wang
- Y Yavuz
- Y Zhao
- ZO Ameur
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/03/2016
- Field of study
X-ray emission from the Sombrero galaxy: discrete sources
- Author
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullin S
- Acosta D
- Acosta JG
- Acosta MV
- Adam N
- Adam W
- Adams MR
- Adams T
- Adiguzel A
- Adler V
- Adzic P
- Agostino L
- Agram JL
- Aguilar-Benitez M
- Aguilo E
- Ahmad M
- Ahmad WH
- Ahmed I
- Ahuja S
- Akchurin N
- Akgun B
- Akgun U
- Akin IV
- Alagoz E
- Albajar C
- Albayrak EA
- Albergo S
- Albrow M
- Alexander J
- Aliev T
- Allfrey P
- Almeida N
- Alver B
- Alverson G
- Alves GA
- Amapane N
- Amsler C
- Anagnostou G
- Anastassov A
- Anderson J
- Anderson M
- Andrea J
- Andreev V
- Andreev V
- Andreev Y
- Andrews W
- Anghel IM
- Antonelli L
- Antunes JR
- Antunovic Z
- Apanasevich L
- Apollinari G
- Appelt E
- Aranyi A
- Arce P
- Arcidiacono R
- Arenton MW
- Arfaei H
- Argiro S
- Arisaka K
- Arneodo M
- Asaadi J
- Asghar MI
- Askew A
- Ata M
- Atac M
- Atramentov O
- Attikis A
- Auffray E
- Autermann C
- Auzinger G
- Avery P
- Avetisyan A
- Awad A
- Azarkin M
- Azhgirey I
- Aziz T
- Azzi P
- Azzolini V
- Azzurri P
- Baarmand MM
- Babb J
- Bacchetta N
- Bachtis M
- Baden A
- Baesso P
- Baffioni S
- Bagliesi G
- Bai Y
- Baillon P
- Bainbridge R
- Bakhshiansohi H
- Bakirci MN
- Bakken JA
- Balazs M
- Ball AH
- Ball G
- Ballin J
- Ban Y
- Bandurin D
- Banerjee S
- Banerjee S
- Bansal S
- Banzuzi K
- Barbagli G
- Barberis E
- Barbone L
- Barge D
- Baringer P
- Barker A
- Barnes VE
- Barnett BA
- Barney D
- Barone L
- Barrett M
- Bartalini P
- Barth C
- Basegmez S
- Basso L
- Battilana C
- Baty C
- Bauer G
- Bauer J
- Bauerdick LAT
- Baumgartel D
- Baur U
- Bazterra VE
- Bean A
- Beauceron S
- Beaudette F
- Beaupere N
- Bedjidian M
- Bedoya CF
- Behrenhoff W
- Behrens U
- Belforte S
- Beliy N
- Bell AJ
- Bell KW
- Bell P
- Bellan P
- Bellan R
- Bellinger JN
- Belotelov I
- Belyaev A
- Benaglia A
- Bencze G
- Bendavid J
- Bender W
- Benedetti D
- Benelli G
- Beni N
- Benucci L
- Benussi L
- Benvenuti AC
- Beretvas A
- Bergauer T
- Bergholz M
- Beri SB
- Bernardini J
- Bernet C
- Berry D
- Berry E
- Berryhill J
- Bertl W
- Berzano U
- Besancon M
- Besson A
- Betchart B
- Betts RR
- Beuselinck R
- Bhat PC
- Bhatnagar V
- Bhattacharya S
- Bhattacharya S
- Bhatti A
- Bialas W
- Bian JG
- Bianchini L
- Bianco S
- Biasini M
- Biino C
- Bilei GM
- Bilinskas MJ
- Bilki B
- Bilmis S
- Biselli A
- Bisello D
- Bitioukov S
- Blekman F
- Bloch D
- Bloch I
- Bloch P
- Bloom K
- Bluj M
- Blumenfeld B
- Blyweert S
- Bobrovskyi S
- Boccali T
- Bocci A
- Bochenek J
- Bodek A
- Bodin D
- Boeriu O
- Boldizsar L
- Bolla G
- Bolognesi S
- Bolton T
- Bonacorsi D
- Bonato A
- Bondar N
- Bondu O
- Bontenackels M
- Boos E
- Borcherding F
- Borgia MA
- Bornheim A
- Borras K
- Borrello L
- Bortignon P
- Bortoletto D
- Bose S
- Bose T
- Bostock F
- Botta C
- Boucerneur M
- Boudoul G
- Boulahouache C
- Boumediene D
- Bourilkov D
- Boutle S
- Braibant-Giacomelli S
- Branca A
- Branson JG
- Breedon R
- Breuker H
- Brew C
- Brigliadori L
- Brigljevic V
- Broccolo G
- Brom JM
- Brona G
- Brooke JJ
- Broutin C
- Brown RM
- Brownson E
- Brun H
- Bruno G
- Bryer AG
- Buchmuller O
- Buege V
- Buehler M
- Bunin P
- Bunkowski K
- Bunn J
- Buontempo S
- Burelo ED
- Burkett K
- Busson P
- Busza W
- Butler JN
- Butler PH
- Butt J
- Butz E
- Bylsma B
- Caballero IG
- Cabrera A
- Cabrillo IJ
- Caebergs T
- Cakir A
- Calabria C
- Calderon A
- Cali IA
- Callner J
- Calvo E
- Camanzi B
- Caminada L
- Campagnari C
- Campbell A
- Campderros JD
- Camporesi T
- Cankocak K
- Cano E
- Capiluppi P
- Caponeri B
- Cappello G
- Cardaci M
- Carlin R
- Carlsmith D
- Carroll R
- Cartiglia N
- Carvalho W
- Castaldi R
- Castello R
- Castro A
- Castro E
- Caudron J
- Cavallari F
- Cavallo FR
- Cavanaugh R
- Ceard L
- Ceballos GG
- Cebra D
- Cepeda M
- Cerati GB
- Cerci S
- Cerizza G
- Cerminara G
- Cerny K
- Ceron C
- Cerrada M
- Chabert EC
- Chadwick M
- Chakaberia I
- Chan M
- Chang P
- Chang S
- Chang YH
- Chang YH
- Chang YW
- Chanon N
- Chao Y
- Charaf O
- Charlot C
- Chasco M
- Chatterjee A
- Chauhan S
- Checchia P
- Chen GM
- Chen HS
- Chen J
- Chen KF
- Chen KH
- Chen M
- Chen WT
- Chen Y
- Chen Z
- Cheng TL
- Chertok M
- Chetluru V
- Cheung HWK
- Chierici R
- Chiochia V
- Chiorboli M
- Chlebana F
- Choi M
- Choi S
- Choi Y
- Choi YK
- Chou JP
- Choudhary BC
- Choudhury RK
- Choudhury S
- Christiansen T
- Chuang SH
- Chung J
- Chung YS
- Chwalek T
- Ciesielski R
- Cifuentes JAB
- Cihangir S
- Cimmino A
- Cirino G
- Cittolin S
- Ciulli V
- Civinini C
- Claes DR
- Clare R
- Clarida W
- Clement E
- Clerbaux B
- Cline D
- CMS Collaboration
- Cockerill DJA
- Codispoti G
- Colafranceschi S
- Colaleo A
- Cole JE
- Cole P
- Colino N
- Collard C
- Colling D
- Conetti S
- Contardo D
- Conte E
- Conte E
- Conway J
- Cooper SI
- Cortabitarte RV
- Cossutti F
- Costa M
- Costa S
- Costantini S
- Coughlan JA
- Cousins R
- Covarelli R
- Cox B
- Cox PT
- Creanza D
- Cremaldi LM
- Cripps N
- Cuevas J
- Cuffiani M
- Cumalat JP
- Cuplov V
- Cure B
- Cushman P
- Cussans D
- Cutajar M
- Cutts D
- Cwiok M
- Czellar S
- D'Agnolo RT
- D'Alessandro R
- D'Alfonso M
- D'Enterria D
- D'Hondt J
- Da Costa EM
- Da Silva WLP
- Dahmes B
- Dahms T
- Dallavalle GM
- Damgov J
- Damiao DD
- Dammann D
- Danielson T
- Darmenov N
- Das S
- Daskalakis G
- Dasu S
- Daubie E
- David A
- Davids M
- Davies G
- De Araujo FTD
- de Barbaro P
- De Benedetti A
- De Boer W
- de Cassagnac RG
- De Cosa A
- de Fatis TT
- De Filippis N
- De Gruttola M
- De Guio F
- De Jeneret JD
- De La Cruz B
- De Lentdecker G
- De Mattia M
- de Monchenault GH
- De Palma M
- De Roeck A
- De Souza SF
- de Troconiz JF
- De Visscher S
- De Wolf EA
- Debreczeni G
- Deisher A
- Deiters K
- Dejardin M
- del Arbol PMR
- Del Re D
- Delaere C
- Deliomeroglu M
- Dell'Orso R
- Della Negra M
- Della Ricca G
- Demaria N
- Demarteau M
- Demin P
- Demina R
- Demir D
- Demir Z
- Demortier L
- Denegri D
- Deniz M
- Depasse P
- Dero V
- Devroede O
- Dhingra N
- Di Giovanni GP
- Di Guida S
- Di Marco E
- Di Matteo L
- Diamond B
- Dias FA
- Dias MAF
- Diemoz M
- Dierlamm A
- Dimitrov A
- Dimitrov L
- Dinardo ME
- Dirkes G
- Dissertori G
- Dittmar M
- Djordjevic M
- Do Amaral SMS
- Dobrzynski L
- Dobur D
- Doesburg R
- Dolen J
- Dominguez A
- Dominik W
- Dorigo T
- Dorney B
- Doroba K
- Dosselli U
- Dozen C
- Draeger J
- Dragicevic M
- Dragoiu C
- Drell BR
- Dremin I
- Drouhin F
- Drozdetskiy A
- Dubinin M
- Duda M
- Dudero PR
- Dudko L
- Dugad S
- Duggan D
- Dumanoglu I
- Duric S
- Duris J
- Durkin LS
- Duru F
- Dusinberre E
- Dutta D
- Dutta S
- Dutta V
- Dyulendarova M
- Dzelalija M
- Eads M
- Eartly DP
- Eckerlin G
- Ecklund KM
- Eckstein D
- Edelhoff M
- Edelmaier CJ
- Eerola P
- Efron J
- Eggert N
- El Mamouni H
- Elliott-Peisert A
- Ellison J
- Elmer P
- Elvira VD
- Enderle H
- Engh D
- Eno SC
- Epshteyn V
- Erbacher R
- Erdmann M
- Erdmann W
- Erhan S
- Ero J
- Ershov A
- Esen S
- Eshaq Y
- Eskew C
- Eskut E
- Etesami SM
- Eugster J
- Eusebi R
- Evangelou I
- Evans D
- Everaerts P
- Everett A
- Fabbri F
- Fabbri F
- Fabbricatore P
- Fabbro B
- Fabjan C
- Fabozzi F
- Faccioli P
- Fahim A
- Falkiewicz A
- Fanfani A
- Fano L
- Fantasia C
- Fanzago F
- Farrell C
- Fasanella D
- Fassi F
- Faure JL
- Favaro C
- Favart D
- Fay J
- Fehling D
- Feindt M
- Felcini M
- Feld L
- Ferapontov A
- Ferencek D
- Ferguson T
- Fernandez M
- Ferrando A
- Ferri F
- Ferro C
- Field RD
- Fields LJ
- Finger M
- Finger M
- Fiore L
- Fiori F
- Fisher M
- Fisk I
- Flacher H
- Flix J
- Florez C
- Flossdorf A
- Flowers K
- Flucke G
- Flugge G
- Foa L
- Focardi E
- Folgueras S
- Fontaine JC
- Ford WT
- Foudas C
- Fouz MC
- Franci D
- Francis B
- Frangenheim J
- Franzoni G
- Frazier R
- Freeman J
- Freudenreich K
- Friedl M
- Friis E
- Frisch B
- Frosali S
- Frueboes T
- Fruhwirth R
- Fu Y
- Fulcher J
- Funk W
- Furic IK
- Futyan D
- Gabathuler K
- Gabella W
- Gaddi A
- Galanti M
- Gallinaro M
- Gallo E
- Gamsizkan H
- Ganjour S
- Gao Y
- Garcia JMV
- Garcia-Abia R
- Garcia-Bellido A
- Garcia-Solis EJ
- Garfinkel AF
- Garrido RGR
- Gartner J
- Gary JW
- Gascon S
- Gasparini F
- Gasparini U
- Gataullin M
- Gaultney V
- Gauthier L
- Gavrilov V
- Gay APR
- Gaz A
- Gebbert U
- Gecse Z
- Geenen H
- Geffert P
- Geiser A
- Gele D
- Genchev V
- Gennai S
- Gentit FX
- Georgiou G
- Geralis T
- Gerbaudo D
- Gerber CE
- Gershtein Y
- Gerwig H
- Geurts FJM
- Ghete VM
- Ghezzi A
- Giacomelli P
- Giammanco A
- Giassi A
- Gibbons LK
- Giffels M
- Gigi D
- Gill K
- Gilmore J
- Giordano D
- Giordano F
- Girgis S
- Giubilato P
- Giunta M
- Giurgiu G
- Givernaud A
- Glege F
- Gleyzer SV
- Glushkov I
- Gninenko S
- Go A
- Gobbo B
- Godang R
- Godinovic N
- Godshalk A
- Goerlach U
- Goh J
- Gokbulut G
- Gokieli R
- Goldberg S
- Goldenzweig P
- Goldstein J
- Golf F
- Gollapinni S
- Golovtsov V
- Golubev N
- Golutvin I
- Gomez G
- Gomez JA
- Gomez JP
- Goncharov M
- Gonzalez JS
- Gonzi S
- Gorski M
- Gotra Y
- Gottschalk E
- Goulianos K
- Gouskos L
- Gouzevitch M
- Govoni P
- Gowdy S
- Grab C
- Grachov O
- Grandi C
- Gras P
- Grassi M
- Gray L
- Gray R
- Graziano A
- Greder S
- Green D
- Gregoire G
- Gregores EM
- Gresele A
- Gribushin A
- Grigelionis I
- Grimes M
- Grishin V
- Gritsan AV
- Grogg KS
- Gronberg J
- Grothe M
- Grunewald M
- Gruschke J
- Gu J
- Guchait M
- Guiducci L
- Guler AM
- Guler Y
- Gulmez E
- Gunthoti K
- Guo S
- Guo Y
- Guo ZJ
- Gupta P
- Gupta R
- Guragain S
- Gurpinar E
- Gurrola A
- Gurtu A
- Gutay L
- Gutsche O
- Haas J
- Hackstein C
- Hadjiiska R
- Hadley NJ
- Hagopian S
- Hagopian V
- Haguenauer M
- Hahn A
- Hahn KA
- Hajdu C
- Halkiadakis E
- Hall G
- Hall-Wilton R
- Halu A
- Halyo V
- Hammad GH
- Hammer J
- Han J
- Hanlon J
- Hansel S
- Hansen M
- Hansen N
- Hanson G
- Harder K
- Harel A
- Harkonen J
- Harper S
- Harr R
- Harris P
- Harris RM
- Hartl C
- Hartley D
- Hartmann F
- Harvey J
- Hashemi M
- Hatakeyama K
- Hatherell Z
- Hauk J
- Haupt J
- Hauser J
- Hays J
- Heath GP
- Heath HF
- Hebbeker T
- Hebda P
- Hegeman J
- Hegner B
- Heikkinen A
- Heindl SM
- Heinrich M
- Heintz U
- Heister A
- Hektor A
- Held H
- Heltsley B
- Henderson C
- Heo SG
- Heracleous N
- Hernandez AS
- Hernandez JM
- Herndon M
- Herve A
- Hesketh G
- Heyburn B
- Heydhausen D
- Hidas D
- Hildreth M
- Hill C
- Hindrichs O
- Hintz W
- Hinzmann A
- Hirosky R
- Hirschauer J
- Hits D
- Hobson PR
- Hoch M
- Hoepfner K
- Hof C
- Hoffmann HF
- Hoffmann KH
- Hofman DJ
- Hohlmann M
- Hollar J
- Hollingsworth M
- Holzner A
- Honc S
- Hong B
- Honma A
- Hooberman B
- Hoorani HR
- Hopkins W
- Horisberger R
- Hormann N
- Horvath D
- Hos I
- Hou WS
- Hreus T
- Hrubec J
- Hsiung Y
- Hu G
- Hu Z
- Huang XT
- Huckvale B
- Hunt A
- Iaselli G
- Iashvili I
- Iaydjiev P
- Ibarguen HAS
- Iglesias LL
- Ignatenko M
- Iiyama Y
- Iles G
- Ille B
- Incandela J
- Ingram Q
- Innocente V
- Iorio AOM
- Isildak B
- Ivanov A
- Ivanov Y
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- Yu SS
- Yumiceva F
- Yun JC
- Zabel J
- Zabi A
- Zablocki J
- Zaganidis N
- Zakaria M
- Zalewski P
- Zanetti M
- Zang J
- Zang SL
- Zarubin A
- Zatserklyaniy A
- Zeinali M
- Zeise M
- Zeuner WD
- Zeyrek M
- Zhang J
- Zhang L
- Zhang Z
- Zheng Y
- Zhokin A
- Zhu B
- Zhu RY
- Zhukov V
- Zhukova V
- Ziebarth EB
- Ziegler J
- Zielinski M
- Zito G
- Zoeller MH
- Zorbilmez C
- Zotto P
- Zou W
- Zumerle G
- Zuranski A
- Publication venue
- 'IOP Publishing'
- Publication date
- 01/01/2010
- Field of study
We present a study of discrete X-ray sources in and around the
bulge-dominated, massive Sa galaxy, Sombrero (M104), based on new and archival
Chandra observations with a total exposure of ~200 ks. With a detection limit
of L_X = 1E37 erg/s and a field of view covering a galactocentric radius of ~30
kpc (11.5 arcminute), 383 sources are detected. Cross-correlation with Spitler
et al.'s catalogue of Sombrero globular clusters (GCs) identified from HST/ACS
observations reveals 41 X-rays sources in GCs, presumably low-mass X-ray
binaries (LMXBs). We quantify the differential luminosity functions (LFs) for
both the detected GC and field LMXBs, whose power-low indices (~1.1 for the
GC-LF and ~1.6 for field-LF) are consistent with previous studies for
elliptical galaxies. With precise sky positions of the GCs without a detected
X-ray source, we further quantify, through a fluctuation analysis, the GC LF at
fainter luminosities down to 1E35 erg/s. The derived index rules out a
faint-end slope flatter than 1.1 at a 2 sigma significance, contrary to recent
findings in several elliptical galaxies and the bulge of M31. On the other
hand, the 2-6 keV unresolved emission places a tight constraint on the field
LF, implying a flattened index of ~1.0 below 1E37 erg/s. We also detect 101
sources in the halo of Sombrero. The presence of these sources cannot be
interpreted as galactic LMXBs whose spatial distribution empirically follows
the starlight. Their number is also higher than the expected number of cosmic
AGNs (52+/-11 [1 sigma]) whose surface density is constrained by deep X-ray
surveys. We suggest that either the cosmic X-ray background is unusually high
in the direction of Sombrero, or a distinct population of X-ray sources is
present in the halo of Sombrero.Comment: 11 figures, 5 tables, ApJ in pres
Jet energy measurement with the ATLAS detector in proton-proton collisions at root s=7 TeV
- Author
- Aad G
- Abbott B
- Abdallah J
- Abdelalim AA
- Abdesselam A
- Abdinov O
- Abi B
- Abolins M
- Abramowicz H
- Abreu H
- Acerbi E
- Acharya BS
- Adams DL
- Addy TN
- Adelman J
- Aderholz M
- Adomeit S
- Adragna P
- Adye T
- Aefsky S
- Aguilar-Saavedra JA
- Aharrouche M
- Ahlen SP
- Ahles F
- Ahmad A
- Ahsan M
- Aielli G
- Akdogana T
- Akesson TPA
- Akimoto G
- Akimov AV
- Akiyama A
- Aktas A
- Alam MA
- Alam MS
- Albert J
- Albrand S
- Aleksa M
- Aleksandrov IN
- Alessandria F
- Alexa C
- Alexander G
- Alexandre G
- Alexopoulos T
- Alhroob M
- Aliev M
- Alimonti G
- Alison J
- Aliyev M
- Allport PP
- Allwood-Spiers SE
- Almenar CC
- Almond J
- Aloisio A
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- Alviggi MG
- Amako K
- Amaral P
- Amelung C
- Ammosov VV
- Amorim A
- Amoros G
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- Zhemchugov A
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- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/03/2013
- Field of study
The jet energy scale and its systematic uncertainty are determined for jets measured with the ATLAS detector at the LHC in proton-proton collision data at a centre-of-mass energy of âs = 7TeV corresponding to an integrated luminosity of 38 pb-1. Jets are reconstructed with the anti-kt algorithm with distance parameters R=0. 4 or R=0. 6. Jet energy and angle corrections are determined from Monte Carlo simulations to calibrate jets with transverse momenta pTâĽ20 GeV and pseudorapidities {pipe}Ρ{pipe}<4. 5. The jet energy systematic uncertainty is estimated using the single isolated hadron response measured in situ and in test-beams, exploiting the transverse momentum balance between central and forward jets in events with dijet topologies and studying systematic variations in Monte Carlo simulations. The jet energy uncertainty is less than 2. 5 % in the central calorimeter region ({pipe}Ρ{pipe}<0. 8) for jets with 60â¤pT<800 GeV, and is maximally 14 % for pT<30 GeV in the most forward region 3. 2â¤{pipe}Ρ{pipe}<4. 5. The jet energy is validated for jet transverse momenta up to 1 TeV to the level of a few percent using several in situ techniques by comparing a well-known reference such as the recoiling photon pT, the sum of the transverse momenta of tracks associated to the jet, or a system of low-pT jets recoiling against a high-pT jet. More sophisticated jet calibration schemes are presented based on calorimeter cell energy density weighting or hadronic properties of jets, aiming for an improved jet energy resolution and a reduced flavour dependence of the jet response. The systematic uncertainty of the jet energy determined from a combination of in situ techniques is consistent with the one derived from single hadron response measurements over a wide kinematic range. The nominal corrections and uncertainties are derived for isolated jets in an inclusive sample of high-pT jets. Special cases such as event topologies with close-by jets, or selections of samples with an enhanced content of jets originating from light quarks, heavy quarks or gluons are also discussed and the corresponding uncertainties are determined. Š 2013 CERN for the benefit of the ATLAS collaboration
Performance of CMS muon reconstruction in pp collision events at sqrt(s) = 7 TeV
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- Yilmaz Y
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- Yumiceva F
- Yun JC
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- Zalewski P
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- Zumerle G
- Zuranski A
- Publication venue
- 'IOP Publishing'
- Publication date
- 01/01/2012
- Field of study
The performance of muon reconstruction, identification, and triggering in CMS
has been studied using 40 inverse picobarns of data collected in pp collisions
at sqrt(s) = 7 TeV at the LHC in 2010. A few benchmark sets of selection
criteria covering a wide range of physics analysis needs have been examined.
For all considered selections, the efficiency to reconstruct and identify a
muon with a transverse momentum pT larger than a few GeV is above 95% over the
whole region of pseudorapidity covered by the CMS muon system, abs(eta) < 2.4,
while the probability to misidentify a hadron as a muon is well below 1%. The
efficiency to trigger on single muons with pT above a few GeV is higher than
90% over the full eta range, and typically substantially better. The overall
momentum scale is measured to a precision of 0.2% with muons from Z decays. The
transverse momentum resolution varies from 1% to 6% depending on pseudorapidity
for muons with pT below 100 GeV and, using cosmic rays, it is shown to be
better than 10% in the central region up to pT = 1 TeV. Observed distributions
of all quantities are well reproduced by the Monte Carlo simulation.Comment: Replaced with published version. Added journal reference and DO
Compressed representation of a partially defined integer function over multiple arguments
- Author
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- Abbiendi G
- Abbrescia M
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- Cuevas J
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- Czellar S
- D'Agnolo RT
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- Da Costa EM
- Dabrowski A
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- Publication venue
- Publication date
- 01/01/2013
- Field of study
In OLAP (OnLine Analitical Processing) data are analysed in an n-dimensional cube. The cube may be represented as a partially defined function over n arguments. Considering that often the function is not defined everywhere, we ask: is there a known way of representing the function or the points in which it is defined, in a more compact manner than the trivial one
Observation of associated near-side and away-side long-range correlations in âsNN=5.02ââTeV proton-lead collisions with the ATLAS detector
- Author
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- Yen AL
- Yilmaz M
- Yoosoofmiya R
- Yorita K
- Yoshida R
- Yoshihara K
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- Young CJ
- Youssef S
- Yu D
- Yu DR
- Yu J
- Yu J
- Yuan L
- Yurkewicz A
- Zabinski B
- Zaidan R
- Zaitsev AM
- Zambito S
- Zanello L
- Zanzi D
- Zaytsev A
- Zeitnitz C
- Zeman M
- Zemla A
- Zenin O
- ZeniĹĄ T
- Zerwas D
- Zevi Della Porta G
- Zhang D
- Zhang H
- Zhang J
- Zhang L
- Zhang X
- Zhang Z
- Zhao L
- Zhao Z
- Zhemchugov A
- Zhong J
- Zhou B
- Zhou N
- Zhou Y
- Zhu CG
- Zhu H
- Zhu J
- Zhu Y
- Zhuang X
- Zhuravlov V
- Zibell A
- Zieminska D
- Zimin NI
- Zimmermann R
- Zimmermann S
- Zimmermann S
- Zinonos Z
- Ziolkowski M
- Zitoun R
- ZivkoviÄ L
- Zmouchko VV
- Zobernig G
- Zoccoli A
- Zur Nedden M
- Zutshi V
- Zwalinski L
- Publication venue
- American Physical Society
- Publication date
- 01/01/2012
- Field of study
Two-particle correlations in relative azimuthal angle (ÎĎ) and pseudorapidity (ÎΡ) are measured in âsNN=5.02ââTeV p+Pb collisions using the ATLAS detector at the LHC. The measurements are performed using approximately 1ââÎźb-1 of data as a function of transverse momentum (pT) and the transverse energy (ÎŁETPb) summed over 3.1<Ρ<4.9 in the direction of the Pb beam. The correlation function, constructed from charged particles, exhibits a long-range (2<|ÎΡ|<5) ânear-sideâ (ÎĎâź0) correlation that grows rapidly with increasing ÎŁETPb. A long-range âaway-sideâ (ÎĎâźĎ) correlation, obtained by subtracting the expected contributions from recoiling dijets and other sources estimated using events with small ÎŁETPb, is found to match the near-side correlation in magnitude, shape (in ÎΡ and ÎĎ) and ÎŁETPb dependence. The resultant ÎĎ correlation is approximately symmetric about Ď/2, and is consistent with a dominant cosâĄ2ÎĎ modulation for all ÎŁETPb ranges and particle pT
Performance of CMS muon reconstruction in pp collision events at sqrt(s) = 7 TeV
- Author
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- Abbiendi G
- Abbrescia M
- Abdullin S
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- Acosta MV
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- Rahbaran B
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- Ranieri R
- Ranjan K
- Rappoccio S
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- Redondo I
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- Reyes-Santos MA
- Ribeiro PQ
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- Rikova MI
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- Roland C
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- Romanowska-Rybinska K
- Romeo F
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- Sengupta S
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- Seo E
- Seo H
- Serban AT
- Serin M
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- Sexton-Kennedy E
- Sfiligoi I
- Sguazzoni G
- Shah MA
- Sharma A
- Sharma A
- Sharma S
- Sharma V
- Sharma V
- Sharp P
- Sheldon P
- Shepherd-Themistocleous CH
- Shi X
- Shipkowski SP
- Shipsey I
- Shiu JG
- Shivpuri RK
- Shmatov S
- Shoaib M
- Shrestha S
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- Shukla P
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- Silverwood H
- Silvestre C
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- Simon M
- Simon S
- Simonetto F
- Simonis HJ
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- Singh G
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- Sirois Y
- Siroli G
- Sirunyan AM
- Skhirtladze N
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- Smirnov I
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- Snigirev A
- Snoek H
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- Snow GR
- Snowball M
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- Soares MS
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- Sobron Sanudo M
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- Wissing C
- Wittich P
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- Won S
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- Wood JS
- Worm SD
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- Wyslouch B
- Xiao H
- Xie S
- Xu M
- Yagil A
- Yalvac M
- Yang F
- Yang M
- Yang Y
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- Yazgan E
- Yelton J
- Yetkin T
- Yi K
- Yildirim E
- Yilmaz Y
- Yohay R
- Yoo HD
- Yoo J
- Yoon AS
- York A
- Yu I
- Yu SS
- Yumiceva F
- Yun JC
- Zabel J
- Zabi A
- Zablocki J
- Zaganidis N
- Zakaria M
- Zalewski P
- Zanetti M
- Zang J
- Zang SL
- Zarubin A
- Zatserklyaniy A
- Zeinali M
- Zeise M
- Zeuner WD
- Zeyrek M
- Zhang J
- Zhang Z
- Zheng Y
- Zhokin A
- Zhu B
- Zhu RY
- Zhukov V
- Zhukova V
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- Zoeller MH
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- Publication venue
- 'IOP Publishing'
- Publication date
- 01/01/2012
- Field of study
The performance of muon reconstruction, identification, and triggering in CMS
has been studied using 40 inverse picobarns of data collected in pp collisions
at sqrt(s) = 7 TeV at the LHC in 2010. A few benchmark sets of selection
criteria covering a wide range of physics analysis needs have been examined.
For all considered selections, the efficiency to reconstruct and identify a
muon with a transverse momentum pT larger than a few GeV is above 95% over the
whole region of pseudorapidity covered by the CMS muon system, abs(eta) < 2.4,
while the probability to misidentify a hadron as a muon is well below 1%. The
efficiency to trigger on single muons with pT above a few GeV is higher than
90% over the full eta range, and typically substantially better. The overall
momentum scale is measured to a precision of 0.2% with muons from Z decays. The
transverse momentum resolution varies from 1% to 6% depending on pseudorapidity
for muons with pT below 100 GeV and, using cosmic rays, it is shown to be
better than 10% in the central region up to pT = 1 TeV. Observed distributions
of all quantities are well reproduced by the Monte Carlo simulation.Comment: Replaced with published version. Added journal reference and DO
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