64 research outputs found
Influence of HAART on Alternative Reading Frame Immune Responses over the Course of HIV-1 Infection
- Author
- A Bansal
- A Masemola
- A Samri
- Aaron M. Hasenkrug
- AC Karlsson
- AG Bruce
- Christopher D. Pilcher
- CT Berger
- D Rimoldi
- DA Meiklejohn
- Douglas F. Nixon
- Esper G. Kallas
- Fredrick M. Hecht
- Gerald E. Spotts
- H Gatanaga
- Hansi Dean
- I Saeterdal
- J Liu
- Jacob C. Miller
- JE Schmitz
- Jeffrey N. Martin
- John L. Lehman
- JV Fetten
- KE Garrison
- Keith E. Garrison
- L Mahnke
- LB Ludwig
- M Altfeld
- M John
- M Probst-Kepper
- M Schmitt
- Marisa Ailin Hong
- MJ McElrath
- MM Addo
- MM Addo
- MR Betts
- Nicholas J. Maness
- NJ Maness
- NJ Maness
- NJ Maness
- NL Michael
- O Ho
- P Borrow
- P Kiepiela
- PA Goepfert
- Paul A. Goepfert
- RB Weiss
- RD Mason
- RF Wang
- Rui André Saraiva Raposo
- S Cardinaud
- S Landry
- S Malarkannan
- S McBratney
- Sean E. Purtell
- SM Mayrand
- SM Mueller
- SM Mueller
- SR Schwab
- Stephane Champiat
- Steven G. Deeks
- TC Friedrich
- TN Bullock
- TN Bullock
- V Novitsky
- Wayne C. Koff
- X Jin
- X Saulquin
- XG Yu
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2012
- Field of study
Background: Translational errors can result in bypassing of the main viral protein reading frames and the production of alternate reading frame (ARF) or cryptic peptides. Within HIV, there are many such ARFs in both sense and the antisense directions of transcription. These ARFs have the potential to generate immunogenic peptides called cryptic epitopes (CE). Both antiretroviral drug therapy and the immune system exert a mutational pressure on HIV-1. Immune pressure exerted by ARF CD8(+) T cells on the virus has already been observed in vitro. HAART has also been described to select HIV-1 variants for drug escape mutations. Since the mutational pressure exerted on one location of the HIV-1 genome can potentially affect the 3 reading frames, we hypothesized that ARF responses would be affected by this drug pressure in vivo. Methodology/Principal findings: In this study we identified new ARFs derived from sense and antisense transcription of HIV-1. Many of these ARFs are detectable in circulating viral proteins. They are predominantly found in the HIV-1 env nucleotide region. We measured T cell responses to 199 HIV-1 CE encoded within 13 sense and 34 antisense HIV-1 ARFs. We were able to observe that these ARF responses are more frequent and of greater magnitude in chronically infected individuals compared to acutely infected patients, and in patients on HAART, the breadth of ARF responses increased. Conclusions/Significance: These results have implications for vaccine design and unveil the existence of potential new epitopes that could be included as vaccine targets.International AIDS Vaccine Initiative (IAVI
Early Detection and Monitoring of Cancer with the Anti-Malignin Antibody Test "
- Author
- /
- A H Liebentritt
- David Marsden
- Elenore S Bogoch
- Ernest E Goins
- Gary Goodfried
- Gary Kimel
- Herbert J Dardik
- James L Mccabe
- Jerry Thornthwaite
- John Imperio
- Karl T Bednarek
- Kenneth Orten
- M Killackey &apos
- M Menasha
- Mark Pasmantier
- Martin B Abrams
- P T Pillai
- Richard A Herrman
- Richard Dowden
- Richard E Layton
- Robert T Whitloc
- Samuel Bogoch
- Stanley Smith
- Stephen C Fox
- Stephen Keuer
- V B Pillai
- Wayne Probst
- William J Turner
- William Jackson
- William Reimer
- Publication venue
- Publication date
- 01/01/1994
- Field of study
ABSTRACT: The serum anti-malignin antibody (AMA) test determines the antibody to malignin. a IO,OOO-Da peptide present in patients with a wide variety of cancers.l~ A total of 3315 double-blind tests demonstrated that AMA is a general transformation antibody, elevated in active no.nterminal cancer, regardless of the site or tissue type, with sensitivity and specificity of95% on the flTst determination and >99% on repeat determinations. - 9 Data have not however been published yet that indicate whether, in daily clinical practice, the AMA test provides accurate prospective and predictive information. Fony-two physicians from II states, who ordered the AMA test, performed blind, report here on their results on 208 determinations in the first consecutive 181 patients and controls. Used in monitoring treatment in 56 patients, the test predicted or agreed 94.1 % overall with the clinical status. Used in early detection in 125 patients and controls, of which 118 now have confirmed diagnoses. AMA was elevated in 21, all of whom were proven to have cancer; AMA was normal in 97, none of whom had cancer. Transient elevated AMA occurred in 3%, followed by normal values. Seven patients with still uncertain diagnosis who have had elevated AMA on repeated tests for I year or longer include six who are symptomatic, and three whose families have a high frequency of cancer. The conditions of these 7 may include undetected cancer because of the 118 with now certain diagnosis the AMA test predicted all correctly. From our experience, the AMA test should be used together with other routine procedures whenever signs and symptoms suggest cancer to facilitate early detection
New genetic loci link adipose and insulin biology to body fat distribution.
- Author
- Aalto Ville
- Aasarød Knut
- Abecasis Goncalo R
- Abecasis Gonçalo
- Absher Devin
- Adair Linda S
- Adam Martin
- Adeyemo Adebowale
- Ahlqvist Emma
- Ahmadi Kourosh R
- Ahola Aila
- Ainali Chrysanthi
- Akylbekova Ermeg
- Ala-Korpela Mika
- Alavere Helen
- Albagha Omar M E
- Albrecht Eva
- Alen Markku
- Alexander Myriam
- Alhenc-Gelas François
- Alizadeh Behrooz Z
- Allison Matthew A
- Alonso Nerea
- Altshuler David
- Ambite Jose Luis
- Amin Najaf
- Amouyel Philippe
- An Ping
- Anderson Carl A
- Anderson Denise
- Anderson Garnet
- Andrews Jeanette S
- Antonella Mulas
- Antti Jula
- Aragaki Aaron K
- Arking Dan E
- Arnold Alice
- Arnold Alice M
- Arora Pankaj
- Arscott Gillian M
- Artigas Maria Soler
- Arveiler Dominique
- Asiki Gershim
- Aspelund Thor
- Assimes Themistocles L
- Atalay Mustafa
- Atkinson Elizabeth J
- Aulchenko Yurii
- Avery Christy
- Bain Stephen C
- Bakker Stephan J L
- Balcells Susana
- Balkau Beverley
- Ballantyne Christie M
- Balmforth Anthony J
- Bandinelli Stefania
- Barbalic Maja
- Barrett Amy
- Barroso Ines
- Barroso Inês
- Basart Hanneke
- Basart Hanneke V
- Bataille Veronique
- Baumert Jens
- Beckmann Jacques S
- Beekman Marian
- Been Latonya F
- Beilby John
- Beilby John P
- Bell Jordana T
- Bellis Claire
- Bennett Amanda J
- Bennett Franklyn
- Berenson Gerald S
- Bergman Richard N
- Bergmann Sven
- Berndt Sonja I
- Berne Christian
- Bidulescu Aurelian
- Bielak Lawrence F
- Bierut Laura J
- Biffar Reiner
- Bis Joshua C
- Blackburn Hannah
- Blangero John
- Blankenberg Stefan S
- Blüher Matthias
- Boban Mladen
- Bochud Murielle
- Boehm Bernhard O
- Boehnke Michael
- Boerwinkle Eric
- Boezen H Marike
- Bolton Jennifer L
- Bolton Judith A Hoffman
- Bonnet Fabrice
- Bonnycastle Lori L
- Boomsma Dorret I
- Borecki Ingrid
- Boright Andrew P
- Borja Judith B
- Bornstein Stefan R
- Boston Jonathan
- Bots Michiel L
- Bouatia-Naji Nabila
- Bouchard Claude
- Bovet Pascal
- Boyd Heather A
- Bragg-Gresham Jennifer L
- Brambilla Paolo
- Brand Eva
- Brand Stefan-Martin
- Brandi Maria Luisa
- Braund Peter S
- Brennan Eoin P
- Brismar Kerstin
- Brody Jennifer
- Broekmans Frank J
- Broer Linda
- Brown Matthew A
- Brown Morris J
- Brown-Gentry Kristin
- Bruinenberg Marcel
- Buchkovich Martin L
- Buckley Brendan M
- Buil Alfonso
- Bull Shelley B
- Burgdorf Christof
- Buring Julie E
- Burnett Mary S
- Burnier Michel
- Burri Andrea
- Burton Paul R
- Bush William S
- Busonero Fabio
- Buxbaum Sarah G
- Buyske Steve
- Buzkova Petra
- Byrne Enda M
- Böger Carsten A
- Böhringer Stefan
- Böttcher Yvonne
- Cambien Francois
- Campbell Harry
- Campbell Susan
- Carba Delia B
- Carlson Chris
- Carlson Olga D
- Carty Cara
- Casas Juan P
- Caspersen Ida H
- Castano-Betancourt Martha
- Cauchi Stéphane
- Cauley Jane A
- Caulfield Mark
- Cavalieri Margherita
- Cazier Jean-Baptiste
- Center Jacqueline R
- Cesana Giancarlo
- Chakravarti Aravinda
- Chambers John
- Chandak Giriraj R
- Chang Hsing-Yi
- Chang Yen-Pei C
- Chanock Stephen J
- Charchar Fadi J
- Chasman Dan
- Chaturvedi Nish
- Chen Constance
- Chen Han
- Chen Ida
- Chen Jin
- Chen Ming-Huei
- Chen Wei
- Chen Yii-Der Ida
- Cheng Iona
- Cheng Sulin
- Chines Peter S
- Cho Yoon Shin
- Choi Murim
- Chouraki Vincent
- Christiansen Claus
- Chu Audrey Y
- Cimponeriu Dan
- Ciullo Marina
- Clark Graeme R
- Clarke Robert
- Claudi-Boehm Simone
- Coassin Stefan
- Cochran Barbara
- Cole Shelley
- Colhoun Helen
- Colhoun Helen M
- Collins Francis S
- Collins Rory
- Connell John M
- Cooper Cyrus
- Cooper Jackie A
- Cooper Matthew N
- Cooper Richard S
- Coresh Josef
- Cornelis Marilyn C
- Corre Tanguy
- Corsi Anna Maria
- Couper David
- Cousminer Diana L
- Coviello Andrea D
- Cox David
- Crawford Dana
- Crisponi Laura
- Croteau-Chonka Damien C
- Cucca Francesco
- Cummings Steven R
- Cupples Adrienne L
- Cupples L Adrienne
- Curhan Gary
- d'Adamo Pio
- Dahgam Santosh
- Dailiana Zoe
- Danesh John
- Danoy Patrick
- Dastani Zari
- Davies Gail
- Daw E Warwick
- Day Felix R
- Day Ian N M
- de Andrade Mariza
- de Boer Ian H
- de Boer Rudolf A
- de Faire Ulf
- de Geus Eco J C
- Deary Ian J
- Dedoussis George
- Dedoussis George V
- Dedoussis George V Z
- Deelen Joris
- Deelman Ewa
- Dehghan Abbas
- Delgado Graciela
- Deloukas Panagiotis
- Deloukas Panos
- Demerath Ellen W
- Demirkan Ayse
- Demirkan Ayşe
- Den Hertog Heleen M
- Denniff Matthew
- Dennison Elaine M
- Dermitzakis Emmanouil T
- Deshmukh Harshal
- Deshmukh Harshal A
- Devuyst Olivier
- di Meglio Paola
- Diemert Patrick
- Dimas Antigone S
- Dimitriou Maria
- Ding Jingzhong
- Do Ron
- Dominiczak Anna F
- Doney Alex
- Dong Yanbin
- Donnelly Louise A
- Doumatey Ayo
- Dreisbach Albert W
- Drong Alexander W
- Duggan David
- Dumitrescu Logan
- Duncan Bruce B
- Duncan Emma L
- Dupuis Josee
- Dupuis Josée
- Durbin Richard
- Durda Peter
- Döring Angela
- Dörr Marcus
- Eastell Richard
- Easton Douglas F
- Ebrahim Shah
- Econs Michael J
- Edkins Sarah
- Egan Josephine
- Ehret Georg
- Eiriksdottir Gudny
- Eisman John A
- Eklund Niina
- El Mokhtari NourEddine
- Elks Cathy E
- Ellinghaus David
- Elliott Paul
- Elosua Roberto
- Emilsson Valur
- Endlich Karlhans
- Epstein Stephen E
- Erbel Raimund
- Erdmann Jeanette
- Erdos Michael R
- Eriksson Joel
- Eriksson Johan
- Eriksson Niclas
- Eriksson Per
- Ernst Florian
- Esko Tonu
- Esko Tõnu
- Esko Tönu
- Estrada Karol
- Eury Elodie
- Evangelou Evangelos
- Evans Alun
- Evans David M
- Eyheramendy Susana
- Eyjolfsson Gudmundur Ingi
- Fagerholm Emma
- Falhammar Henrik
- Fall Tove
- Farrall Martin
- Fauser Bart C J M
- Fava Cristiano
- Feenstra Bjarke
- Fehrmann Rudolf
- Feitosa Mary
- Feranil Alan B
- Ferrannini Ele
- Ferrario Marco M
- Ferreira Teresa
- Ferreli Liana
- Ferrières Jean
- Ferrucci Luigi
- Fischer Krista
- Florez Jose C
- Folkersen Lasse
- Folsom Aaron R
- Fontanillas Pierre
- Ford Ian
- Fornage Myriam
- Foroud Tatiana
- Forouhi Nita G
- Forrester Terrence
- Forsblom Carol
- Foster Meredith C
- Fowke Jay
- Fowkes F Gerald R
- Fowkes Gerard R
- Fox Caroline S
- Fox Ervin R
- Franceschini Nora
- Franco Oscar H
- Franco-Cereceda Anders
- Franke Andre
- Franke Lude
- Franks Paul W
- Frants Rune
- Fraser Ross M
- Frayling Timothy M
- Freedman Barry I
- Freimer Nelson B
- Freitag Daniel F
- Friedrich Nele
- Froguel Philippe
- Frost Morten
- Fuchsberger Christian
- Galan Pilar
- Ganesh Santhi K
- Ganna Andrea
- Gansevoort Ron T
- Gao Xiaoyi
- Garcia Melissa
- Garcia-Giralt Natàlia
- Garnaas Maija
- Gasparini Paolo
- Gauguier Dominique
- Gaunt Tom R
- Gautvik Kaare M
- Geller Frank
- Gharavi Ali G
- Giedraitis Vilmantas
- Gieger Christian
- Gierman Hinco J
- Gigante Bruna
- Gill Geoffrey V
- Giroux Sylvie
- Giulianini Franco
- Glass Daniel
- Glazer Nicole
- Glazer Nicole L
- Glenn Kim
- Glorioso Nicola
- Go Alan S
- Go Min Jin
- Godson Catherine
- Goel Anuj
- Goessling Wolfram
- Golay Alain
- Goldstein Benjamin A
- Goltzman David
- Gong Jian
- González-Macías Jesús
- Goodall Alison H
- Goodarzi Mark O
- Goodloe Robert
- Gordin Daniel
- Gordon Scott D
- Gorski Mathias
- Grabe Hans-Jörgen
- Graff Misa
- Grallert Harald
- Grammer Tanja B
- Gravito Martha L
- Greenwood Celia M T
- Grewal Jagvir
- Grimsby Jonna
- Grobbee Diederick E
- Groop Leif
- Groop Per-Henrik
- Gross Myron
- Groves Christopher J
- Grundberg Elin
- Grässler Jürgen
- Gräßler Jürgen
- Gu Harvest F
- Gu Tianwei
- Guarrera Simonetta
- Gudbjartsson Daniel F
- Gudnason Villi
- Gudnason Vilmundur
- Guiducci Candace
- Guo Qun
- Guo Xiuqing
- Gurdasani Deepti
- Gustafsson Stefan
- Gyllensten Ulf
- Gyllensten Ulf B
- Hadjadj Samy
- Hadley David
- Haessler Jeff
- Hager Jörg
- Haiman Christopher
- Haines Jonathan
- Hall Alistair S
- Hall Per
- Hallan Stein
- Haller Toomas
- Hallmans Goran
- Hallmans Göran
- Hamsten Anders
- Han Bok-Ghee
- Hankinson Susan E
- Hanson Robert L
- Hardy Rebecca
- Haritunians Talin
- Harjutsalo Valma
- Harris Tamara
- Hartikainen Anna-Liisa
- Hartman Catharina A
- Hass Merli
- Hassanali Neelam
- Hassinen Maija
- Hastie Nicholas D
- Hastie Nick
- Hattersley Andrew T
- Haun Margot
- Havulinna Aki S
- Hayward Caroline
- Hazen Stanley L
- He Bing
- He Chunyan
- Heard-Costa Nancy L
- Heath Andrew C
- Heath Simon
- Heckbert Susan R
- Hedblad Bo
- Hedman Åsa K
- Heid Iris M
- Heikkilä Kauko
- Heikkilä Outi
- Heiss Gerardo
- Heliövaara Markku
- Helmer Catherine
- Helmer Quinta
- Henders Anjali K
- Henderson Brian
- Hengstenberg Christian
- Henneman Peter
- Hercberg Serge
- Herder Christian
- Hernandez Dena
- Hernandez Dena G
- Herrera Lizbeth
- Herzig Karl-Heinz
- Hicks Andrew A
- Hietala Kustaa
- Higashio Julia
- Hillege Hans L
- Hilton Gina
- Hindorff Lucia
- Hingorani Aroon
- Hirschhorn Joel N
- Hivert Marie-France
- Ho Weang K
- Hocking Lynne J
- Hoffmann Wolfgang
- Hofman Albert
- Holliday Elizabeth G
- Holm Hilma
- Holmen Oddgeir
- Homuth Georg
- Hopewell Jemma C
- Horikoshi Momoko
- Hosseini Mohsen
- Hottenga Jouke-Jan
- Hovingh G Kees
- Howard Philip
- Hsiung Chao Agnes
- Hsu Yi-Hsiang
- Hu Frank B
- Huang Huateng
- Huang Jinyan
- Hui Jennie
- Humphries Steve E
- Hundertmark Claudia
- Hung Yi-Jen
- Hunt Sarah E
- Hunt Steven C
- Hunter David J
- Husted Lise Bjerre
- Hveem Kristian
- Hwang Shih-Jen
- Hyppönen Elina
- Igl Wilmar
- Ikram M Arfan
- Illig Thomas
- Imboden Medea
- Ingelsson Erik
- Ingle Catherine
- Ingvarsson Thorvaldur
- Ioannidis John P A
- Iribarren Carlos
- Isaacs Aaron
- Isakova Tamara
- Islam Muhammad
- Ittermann Till
- Iwai Naoharu
- Jackson Anne U
- Jackson Rebecca
- Jacobs Gunnar
- Jafar Tazeen H
- James Alan L
- Jameson Karen A
- Jang Yangsoo
- Janipalli Charles S
- Jansen Hanneke
- Janssens A Cecile J W
- Jarvelin Marjo-Riitta
- Jeff Janina
- Jenny Nancy
- Johannsdottir Hrefna
- Johansen Berit
- Johansson Ingegerd
- Johansson Åsa
- Johnson Andrew
- Johnson Louise
- Johnson Paul C D
- Johnson Toby
- Jones Graeme
- Jones Michelle R
- Jousilahti Pekka
- Ju Sung Yun
- Jukema J Wouter
- Jula Antti
- Juliusdottir Thorhildur
- Justice Anne E
- Järvelin Marjo-Riitta
- Jöckel Karl-Heinz
- Kaakinen Marika
- Kahali Bratati
- Kalafati Ioanna-Panagiota
- Kaleebu Pontiano
- Kammerer Candace M
- Kanaya Alka
- Kang Hyun M
- Kang Hyun Min
- Kangas Antti J
- Kanoni Stavroula
- Kao Linda
- Kao W H L
- Kao Wen Hong Linda
- Kaplan Robert C
- Kaprio Jaakko
- Kaptoge Stephen K
- Kapur Karen A
- Karasik David
- Kardia Sharon L
- Karjalainen Juha
- Karlsson Magnus
- Karpe Fredrik
- Kastelein John J P
- Kathiresan Sekar
- Katsareli Efi
- Kedenko Lyudmyla
- Kee Frank
- Keildson Sarah
- Keinanen-Kiukaanniemi Sirkka M
- Keller Benjamin J
- Kemp John P
- Kennedy Stephen H
- Kessler Thorsten
- Kestenbaum Bryan
- Kesäniemi Antero
- Ketkar Shamika
- Kettunen Johannes
- Keyzer Jules
- Khaw Kay-Tee
- Khusainova Rita
- Khusnutdinova Elza
- Kiel Douglas P
- Kiess Wieland
- Kilpeläinen Tuomas O
- Kim Eric
- Kim Ghi Su
- Kim Hyo-Soo
- Kim Hyung-Lae
- Kim Stuart K
- Kinnunen Leena
- Kinra Sanjay
- Kiryluk Krzysztof
- Kita Yoshikuni
- Kivimaki Mika
- Kizer Jorge R
- Klaric Irena Martinovic
- Kleber Marcus E
- Klopp Norman
- Kloppenburg Margreet
- Knowles David
- Knowles Joshua W
- Kocarnik Jonathan
- Koenig Wolfgang
- Koh Jung-Min
- Kolcic Ivana
- Koller Daniel L
- Kollerits Barbara
- Kollia Panagoula
- Kolonel Laurence
- Kolovou Genovefa
- Komulainen Pirjo
- Kong Augustine
- Kooner Ishminder K
- Kooner Jaspal
- Kooperberg Charles
- Koromila Theodora
- Koudstaal Peter J
- Kovacs Peter
- Kraft Peter
- Kraja Aldi T
- Kramer Holly
- Kratzer Wolfgang
- Krauss Ronald M
- Krestyaninova Maria
- Kretzler Matthias
- Kristiansson Kati
- Kroemer Heyo K
- Kronenberg Florian
- Kruk Marcin
- Krämer Bernhard K
- Kuh Diana
- Kulkarni Smita R
- Kuller Lew
- Kumar M J Kranthi
- Kumari Meena
- Kung Annie Wai Chee
- Kutalik Zoltan
- Kutalik Zoltán
- Kuulasmaa Kari
- Kuusisto Johanna
- Kuznetsova Tatiana
- Kwan Tony
- Kytö Janne
- Kyvik Kirsten O
- Kähönen Mika
- König Inke R
- Körner Antje
- Köttgen Anna
- Laakso Markku
- Laaksonen Marika
- Laaksonen Reijo
- Laan Maris
- LaCroix Andrea
- Lacroix Andrea Z
- Ladenvall Claes
- Ladouceur Martin
- Lagou Vasiliki
- Lahermo Päivi
- Lahti Jari
- Lai Sandra
- Laisk Triin
- Laitinen Jaana
- Lajer Maria
- Lakatta Edward G
- Lakka Timo A
- Lambert Ann
- Lamina Claudia
- Langdahl Bente Lomholt
- Langefeld Carl D
- Langenberg Claudia
- Langford Cordelia
- Larson Martin
- Larson Martin G
- Lathrop Mark
- Lauc Lovorka Barac
- Launer Lenore
- Laven Joop S E
- Lawlor Debbie A
- Lawrence Robert W
- Le Marchand Loic
- Le Marchand Loïc
- Leak Tennille S
- Leander Karin
- Lecoeur Cecile
- Lee Ji-Young
- Lee Jong-Young
- Lee Nanette R
- Lee Sang Hong
- Lee Seung Hun
- Lefebvre Pierre
- Lehtimäki Terho
- Lehto Markku
- Leo Paul J
- Leslie William D
- Leung Ping C
- Levy Daniel
- Lewis Joshua R
- Li Guo
- Li Man
- Li Rui
- Li Shengxu
- Li Xiaohui
- Li Yali
- Liang Liming
- Lichtner Peter
- Lifton Richard P
- Lim Unhee
- Lin Danyu
- Lin Peng
- Lin Shih-Yi
- Lin Yi
- Lind Lars
- Lindgren Cecilia M
- Lindström Jaana
- Lips Paul
- Liu Ching-Ti
- Liu Jianjun
- Liu Yongmei
- Ljunggren Östen
- Lobbens Stéphane
- Locke Adam E
- Lohman Kurt
- Lohman Kurt K
- Lokki Marja-Liisa
- Longstreth W T
- Loo Britt-Marie
- Loos Ruth J F
- Lopez Lorna M
- Lorenc Roman S
- Lorentzon Mattias
- Louwers Yvonne V
- Lowe Christopher E
- Lu Xiaoning
- Luan Jian'an
- Luben Robert
- Lucas Gavin
- Ludwig Barbara
- Lumley Thomas
- Lundmark Anders
- Lundmark Per
- Lunetta Kathryn L
- Lyssenko Valeriya
- Lyytikainen Leo-Pekka
- Lyytikäinen Leo-Pekka
- Ma Baoshan
- MacCluer Jean
- Macgregor Stuart
- Mach François
- Maerz Winfried
- Maestroni Anna
- Maestroni Silvia
- Magnusson Patrik K E
- Mahajan Anubha
- Malinowski Jennifer
- Mangino Massimo
- Mani K Radha
- Manning Alisa K
- Manolio Teri
- Maouche Seraya
- Marc Janja
- Marette André
- Marmot Michael G
- Marongiu Mara
- Marre Michel
- Martin Finian
- Martin Nicholas G
- Marullo Letizia
- Masciullo Corrado
- Masi Laura
- Mateo Leach Irene
- Matise Tara
- Mattace-Raso Francesco U S
- Matullo Giuseppe
- Maxwell Alexander P
- McArdle Patick F
- McArdle Patrick F
- McArdle Wendy L
- McCarthy Mark I
- McCloskey Eugene
- McKay Gareth J
- McKenzie Colin A
- McKnight Amy J
- McKnight Amy Jayne
- McKnight Barbara
- McPherson Ruth
- Medina-Gomez Carolina
- Medina-Gómez Carolina
- Medland Sarah E
- Meduri Eshwar
- Meigs James B
- Meisinger Christa
- Meitinger Thomas
- Melander Olle
- Melbye Mads
- Mellström Dan
- Melzer David
- Mencej-Bedrac Simona
- Meneton Pierre
- Menni Cristina
- Merger Sigrun
- Meschia James F
- Metspalu Andres
- Metzger Marie
- Meulenbelt Ingrid
- Mihai Ioana
- Mihailov Evelin
- Miki Tetsuro
- Milaneschi Yuri
- Milani Lili
- Miljkovic Iva
- Mills Rebecca
- Min Josine L
- Minelli Cosetta
- Minster Ryan L
- Mirel Daniel B
- Missmer Stacey A
- Mitchell Braxton D
- Mitchell Paul
- Mitchell Sabrina L
- Moayyeri Alireza
- Moffatt Miriam F
- Mohlke Karen L
- Moilanen Leena
- Monda Keri L
- Monroe Kristine
- Montasser May E
- Montgomery Grant W
- Montgomery Stephen B
- Mooijaart Simon P
- Mooser Vincent
- Mora Samia
- Morken Mario A
- Morris Andrew D
- Morris Andrew P
- Morris Richard W
- Morrison Alanna C
- Mosley Thomas H
- Mota Eugen
- Mota Maria
- Mulas Antonella
- Munroe Patricia
- Murabito Joanne M
- Murdock Deborah
- Murgia Federico
- Murray Anna
- Murray Jeffrey C
- Murray Sarah S
- Musani Solomon
- Musk Arthur W
- Mychaleckyj Josyf C
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- Wilson Scott G
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- Witteman Jacqueline C
- Witteman Jacqueline C M
- Wojczynski Mary K
- Wolffenbuttel Bruce H R
- Wong Andrew
- Wong Tien Y
- Woo Jean
- Wood Andrew R
- Wood Andy
- Workalemahu Tsegaselassie
- Wright Alan F
- Wu Chunyuan
- Wu Joseph M W
- Wu Ying
- Würtz Peter
- Xiao Su-Mei
- Yajnik Chittaranjan S
- Yang Jian
- Yang Qiong
- Yang Tsun-Po
- Yao Jie
- Yengo Loïc
- Yerges-Armstrong Laura M
- Young Alicia
- Young Elizabeth H
- Young J H
- Young Lauren
- Yuan Xin
- Zaboli Ghazal
- Zalloua Pierre A
- Zarrabeitia María T
- Zelenika Diana
- Zemunik Tatijana
- Zerbini Gianpaolo
- Zgaga Lina
- Zhai Guangju
- Zhang Feng
- Zhang Qunyuan
- Zhang Weihua
- Zhao Jing Hua
- Zhao Wei
- Zheng Hou-Feng
- Zheng Wei
- Zhou Yanhua
- Zhu Haidong
- Zhu Kun
- Zhu Xiaofeng
- Zhuang Wei V
- Zhuang Wei Vivian
- Ziegler Andreas
- Zillikens M Carola
- Zimmermann Martina E
- Zitting Paavo
- Zondervan Krina T
- Zukowska-Szczechowska Ewa
- Zygmunt Marek
- Ärnlöv Johan
- Österholm Anne-May
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2015
- Field of study
Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic outcomes, independent of overall adiposity. To increase our understanding of the genetic basis of body fat distribution and its molecular links to cardiometabolic traits, here we conduct genome-wide association meta-analyses of traits related to waist and hip circumferences in up to 224,459 individuals. We identify 49 loci (33 new) associated with waist-to-hip ratio adjusted for body mass index (BMI), and an additional 19 loci newly associated with related waist and hip circumference measures (P < 5 × 10(-8)). In total, 20 of the 49 waist-to-hip ratio adjusted for BMI loci show significant sexual dimorphism, 19 of which display a stronger effect in women. The identified loci were enriched for genes expressed in adipose tissue and for putative regulatory elements in adipocytes. Pathway analyses implicated adipogenesis, angiogenesis, transcriptional regulation and insulin resistance as processes affecting fat distribution, providing insight into potential pathophysiological mechanisms
Impact of COVID-19 on cardiovascular testing in the United States versus the rest of the world
- Author
- Abad Pedro
- Abbara Suhny
- Abbasi Taimur
- Abbott Brian
- Abdel Aziz Islam Shawky
- Abdulla Jawdat
- Abikhzer Gad
- Abohashem Shady
- Abougabal Mahasen
- Abramson Sandra
- Abrihan Paz
- Acuña Arturo Romero
- Affandi Erwin
- Afzal Muhammad Shehzad
- Agolti Mariela
- Agranovich Svetlana
- Aguadé-Bruix Santiago
- Aguero Roberto Nicolas
- Ahmed Hassan Mohamed Ismail
- Ahmed Taghreed
- Akhter Afroza
- Al Dhuhli Humoud
- Al Kindi Faiza
- Al-Abboud Tarek
- Al-Bulushi Naeema
- Al-Mallah Mouaz
- Alak Maria del Carmen
- Alam Edison
- Alaoui Nadia Ismaili
- Alasnag Mirvat
- Albadr Amjed
- Albalooshi Batool
- Albano Domenico
- Alberguina Lucia Graciela
- Albernaz Siqueira Maria Helena
- Alexanderson-Rosas Erick
- Alfaro Ana
- Ali Mohamed Mandour
- Alkadhi Hatem
- Alkandari Faridah
- Allam Adel
- Allarakha Mohammad Aaftaab
- Almeida Augusto
- Almousalli Omar
- Alongi Pierpaolo
- Alonso Omar
- Alves Togni Paulo Henrique
- Alves Wilson Furlan
- Ananthasubramaniam Karthikeyan
- Anderson Jill
- Andrade Jose Henrique
- Andrade Luciana
- Angelidis George
- Anselmi Carlos
- Ansheles Alexey
- Araújo Roberta
- Archontaki Aikaterini
- Arnone Gaspare
- Arnous Samer
- Arnson Yoav
- Arroñada Guillermo
- Arturo Harold
- Asano Hiroshi
- Ascani Sebastian Perez
- Asfour Ahmed
- Askew Jeffrey
- Assadi Majid
- Astesiano Alfredo
- Astesiano Andrea
- Attanasio Lea
- Atyani Said
- Ayala Sandra
- Ayetey Harold
- Ayodele Tolulope
- Azevedo Guilherme
- Bagatin Elisa
- Bailly Matthieu
- Baldari Sergio
- Balmer-Swain Mallory
- Bang Ji-In
- Banthia Nilesh
- Bar-Shalom Rachel
- Barette Rene
- Baric Ana
- Barneveld Peter
- Barragan Adriana Puente
- Barragan Erika
- Barroso Asela
- Basavaraj Ashok Gangasandra
- Batinic Tonci
- Batista Juan Felipe
- Batyrkhanov Daultai
- Bauckneht Matteo
- Baugh Dainia
- Bayer Richard R.
- Bedi Punit
- Bejai Shereen
- Ben-Rais Nozha
- Benedek Imre
- Benedek Theodora
- Benitez Luis
- Benlabgaa Rabie
- Bennie George
- Benteo Pablo
- Beretta Mario
- Berman Daniel S.
- Bernheim Adam
- Bertelli Paolo
- Bester Ria
- Bettencourt Nuno
- Better Nathan
- Better Nathan
- Beuzeville Scott
- Bezerra Sabbrina
- Bhagat Jinendra Kumar
- Bhargava Rishi
- Bhat Vivek
- Bhatia Mona
- Bhatti Sabha
- Biancardi Rodrigo
- Bianco Francesco
- Bieging Erik
- Biggans Thomas
- Bittencourt Marcio Sommer
- Blanco Isabel
- Blanco Juan
- Blankstein Ron
- Blankstein Ron
- Bloom Stephen
- Blue Sean
- Bluemke David
- Bluemke David A.
- Boktor Raef
- Bom Henry
- Bonelli Juan Manuel
- Bonfiglioli Rachele
- Boni Roberto
- Borges Andressa
- Bouyoucef Salah
- Branch Kelley
- Brandão Simone
- Bravo Paco
- Brothers Jessica
- Bruno Andrea
- Bruno Isabella
- Bråten Anders Tjellaug
- Budoff Matthew
- Buechel Ronny Ralf
- Buga Klara
- Bularga Anda
- Bull Russell
- Bullock-Palmer Renée
- Burandt Angela
- Burg Samuel
- Burger Peter
- Burgul Rajesh
- Burke Floyd W.
- Bush Kelvin
- Busnardo Elena
- Bustos Jose Javier
- Butler Patrick
- Byrne Angela
- Bøttcher Morten
- Cabada Manuel
- Cabeda Estevan Vieira
- Cabrejas Raul
- Cabrera Antonio
- Cachero Jorge
- Cadena Alberto
- Caicedo Carlos
- Calcott Jennifer
- Califaretti Elena
- Camarero Alicia
- Camoni Luca
- Campisi Roxana
- Canal Maria Pedrera
- Candela Candace
- Canderoli Alejandro
- Canessa Jose
- Cantinho Guilhermina
- Cao Dianbo
- Capasso Elizabeth
- Carames Silvia
- Carnevale Aldo
- Carpenter John-Paul
- Carr Loretta
- Carrascosa Patrícia
- Carreira Lara
- Carvajal-Juarez Isabel
- Casoni Roberta
- Castro Bruno
- Castro Gabriel
- Castro Ricardo
- Casáns-Tormo Irene
- Cavalcante Joao
- Cavallo Armando Ugo
- Cavenaghi Giorgio
- Cendoya Oscar
- Cerci Rodrigo
- Cerci Rodrigo J.
- Ceriani Luca
- Chambers Duane
- Chan Virgil
- Chang Donald
- Chang Tien
- Chao Charles
- Chatterjee Saurav
- Chatziioannou Sofia
- Chatzizisis Yiannis
- Cheezum Michael
- Chen Jennifer
- Chen Marcus
- Chen Tiffany
- Cheung Stephen
- Chierichetti Franca
- Chimura Chimura Misato
- Chiocchi Marcello
- Cho Sang-Geon
- Choi Andrew
- Choi Andrew
- Choi Andrew D.
- Chong Woon
- Choudhury Partha
- Chow Benjamin
- Chowdekar Vijay Sai
- Christensen Mette
- Cittanti Corrado
- Clarcq James
- Cognigni Luciano Martin
- Cohen Yosef
- Cohen Yosef A.
- Coie Tchoyoson Lim
- Coles Duncan
- Collaud Carlos
- Collaud Carlos
- Colletta Mauro
- Concha Carmen
- Conti Umberto
- Cordero Ayreen
- Cortes Claudia
- Cortés Filiberto
- Cortés Violeta
- Cossu Alberto
- Courtis Javier
- Cragnolino Daniel
- Crim Matthew
- Cruz Eric
- Cuadra Teresa
- Cuellar-Calabria Hug
- Cunali Fernando
- Cuocolo Alberto
- Cury Roberto
- Cusack David
- Cuzzocrea Marco
- Dabreo Dominique
- Dai Xu
- Daicz Mariana
- Danciu Sorin
- Dantas Roberto
- Dariy Olga
- Datseris Ioannis
- Dautov Tairkhan
- de Amorim Fernandes Fernando
- De Boeck Bart
- De Carvalho Filipe Penna
- De La Peña Erasmo
- De La Vega Alejandro
- De Lorenzo Andrea
- De Macedo Filho Robson
- De Maria Silvia Teresa
- De Rimini Maria Luisa
- De Souza Thiago Ferreira
- De Vincentis Giuseppe
- Decter Bruce
- Del Giudice Eleonora
- Del Riego Horacio
- Del Torto Alberico
- Della Tommasina Veronica
- Deshpande Aparna
- Dettori Fernando
- Deux Jean-François
- Deviggiano Alejandro
- Dhruva Nimish
- Diaz Javier Lopez
- Djuraev Omoa
- Dobson Mark
- Doherty Neil
- Dondi Maurizio
- Dondi Maurizio
- Dorbala Sharmila
- Dorbala Sharmila
- Dougan John
- Doukky Rami
- Downie D'Arne
- Dragonetti Laura
- Drozdova Olga
- Dunbar Anjori
- Durmo Rexhep
- Duvall William
- Dwivedi Girish
- Edmond John
- Edwards Rachael
- Efros-Monsen Elen
- Einstein Andrew J.
- Einstein Andrew J.
- Elison Barry
- Ellis Chris
- Emami Farshad
- Embon Mario
- Engela Jean
- Engelbrecht Gerrit
- Engelmann Vaclav
- Enriquez Ruben Emilio
- Ensinas Jorge
- Erba Paola Anna
- Erthal Fernanda
- Escobar Manuel Valencia
- Escorza Velez Giovanni Alejandro
- Espeche Maria del Huerto Velazquez
- Esquitin Kerry
- Evangelista Laura
- Evbuomwan Osayande
- Faccio Fernando
- Facello Adolfo
- Fairbairn Timothy
- Faletti Riccardo
- Faragasso Evelina
- Faraggi Marc
- Farah Husam
- Farrugia Alexia
- Farsad Mohsen
- Fatima Shazia
- Fentanes Emilio
- Ferencik Maros
- Ferencik Maros
- Fernandes Fabio
- Fernandes Fabio
- Fernandes Juliano
- Ferrando Rodolfo
- Ferreira Antonio
- Ferro Paola
- Feuchtner Gudrun
- Fisher Daniel
- Fitzpatrick Daniel
- Flores Ana Camila
- Florimonte Luigia
- Flotats Albert
- Forsdahl Signe Helene
- Foster Cameron
- Fragkaki Christina
- Franceschi Maja
- Francis Roslyn
- Frantellizzi Viviana
- Frenkel Alex
- Friedrich Matthias
- Fringuelli Fabio Massimo
- Fuentes Cañamero Maria Eugenia
- Fuisz Tony
- Fujimoto Shinichiro
- Fujisue Koichiro
- Fukunaga Tomohisa
- Fukushima Yoshimitsu
- Fukuyama Kae
- Gagarina Nina
- Gaikwad Anand
- Gama-Moreno Manlio
- Gamboa Isabel Berrocal
- Gannon Michael
- Garai Ildiko
- Garashi Masoud
- Garcheva-Tsacheva Marina
- García María Elia
- Garg Ria
- Garofalo Diego
- Gastner Lori
- Gatti Marco
- Gaudiano Angela
- Georgoulias Panagiotis
- Geronazzo Ricardo
- Gerson Myron
- Gheysens Olivier
- Ghimire Ram Kumar
- Ghini Bruno
- Ghoshhajra Brian
- Gimelli Alessia
- Girijanandan Mahapatra Prof Dr
- Giubbini Raffaele
- Giuffrida Francesca
- Glaudemans Andor
- Gleeson Tadhg
- Goda Artan
- Goebel Benjamin
- Goebel Benjamin
- Goldberg Alan
- Goldner Brian
- Gomez Marie Rhiamar
- Gomez Sharon
- Goncalves Luiz
- Gong Lianggeng
- Gongxeka Harlem
- Gonza Natalia
- Gonzalez Carla
- Gonzalez Jorge
- González Luis
- González Ulises
- González-Montecinos Alejandro Becerril
- Goodwin Bruce
- Gopalan Deepa
- Gore Rosco
- Gormsen Lars Christian
- Gottlieb Ilan
- Gracia-López Sandra
- Greenough Robert
- Grossman Gabriel Blacher
- Gräni Christoph
- Gulyaev Vsevolod Milyevich
- Gummow Alistair
- Gunawan Gani
- Gutierrez Villamil Claudia T.
- Gutierrez Goleat
- Gutierrez Lucas
- Gutierrez Yamile Marcos
- Gutierrez Yamile Marcos
- Guzzo Miguel Angel
- Guzzo Miguel Angel
- Gómez Lauchy Juan Manuel
- Habets Jesse
- Habouzit Vincent
- Hadlich Marcelo
- Hafez Mohammed Nassoh
- Hage Fadi
- Haidar Mohamad
- Haider Agha
- Haider Sofia
- Hamilton Mark
- Hamilton-Craig Christian
- Hamirani Yasmin
- Han Dan
- Hapkido Habusari
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- Hasbak Philip
- Hasbani Victor
- Hashimoto Jun
- Hassan Alia
- Hassan Mona
- Hassen Karen
- Hatfield Mallory
- Hawkins Carolyn
- Hawthorne Katie
- Heath Nicholas
- Hendel Robert
- Hernandez Phillip
- Hernández Gertrudis Sabatel
- Herrera Yariela
- Hess Søren
- Hidalgo Pablo
- Hidayat Basuki
- Hildre Dimmen Jenni-Mari
- Hill Gregory
- Hinterleitner Gerd
- Hirschfeld Cole B.
- Hirschfeld Cole B.
- Holdgaard Paw
- Homans Filip
- Hong Chae Moon
- Horgan Stephen
- Hou Yang
- Houshmand Golnaz
- Hsieh Victar
- Hua Shaw
- Huda Aulia
- Hudson Benjamin
- Huerin Melina
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- Ialuna Salvatore
- Ibrahim Ahmed
- Ichikawa Yasutaka
- Iguchi Nobuo
- Iii George Kinzfogl
- Ilic Srdja
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- Kaffas Sameh
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- Kalra Dinesh
- Kamani Christel H.
- Kameoka Vinícius
- Kaminek Milan
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- Kang Won Jun
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- Kaplan Mitchell
- Karalkin Anatoly
- Karim Noor Khairiah A.
- Kato Takao
- Kaviratne Summanther
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- Kay Michael
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- Kudo Takashi
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- Leipsic Jonathon
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- Leta Rubén
- Leung Eugene
- Leung Steve
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- Lewkowicz Julio Manuel
- Li Caiying
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- Liguori Carlo
- Lima Adna
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- Litmanovich Diana
- Liu Hui
- Liu Jinkang
- Liu Yiyan
- Londoño Blair Juan Luis
- Londoño Juan
- Longo Giampiero
- Lopes Rafael Willain
- Lopez-Mattei Juan
- Lopez-Mattei Juan
- Lopez-Mattei Juan
- Lotti Jose Maria
- Louw Lizette
- Lovera Cesar
- Low Chen
- Lu Bin
- Lu Bin
- Lu Yao
- Lugassi Rachel
- Luis Rodrigues Jonathan Carl
- Lumbreras Luis
- Luna Hiram Rivera
- Løvhaugen Pål
- Machado e Silva Ricardo
- Madu Chibuzo
- Madu Ernest
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- Magalhães Tiago
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- Magurany Kathleen
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- Mak Sze Mun
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- Malan Nico
- Maldonado Alejandro
- Maleki Majid
- Malkovskiy Eli
- Malkovskiy Eli
- Mancini Maria Elisabetta
- Mander Gordon
- Manders Jeroen
- Manka Robert
- Mansy Ahmad
- Maor Moalem Israel Shlomo
- Marcassa Claudio
- Markowitz Jeremy
- Marn Amanda
- Marousa Ntouskou
- Maroz-Vadalazhskaya Natallia
- Marquez Alejandra
- Marquez-Cabeza Juan Javier
- Martin Francisco
- Martin Jon
- Martinez de Alegria Anxo
- Maruno Hirotaka
- Masoli Osvaldo
- Masoli Osvaldo Horacio
- Massardo Teresa
- Mastrocola Luiz Eduardo
- Mastrovito Edgardo
- Mataciunas Mindaugas
- Mataki Hiroyuki
- Matis Stephen E.
- Matos Luis
- Matushita Cristina Sebastião
- Maurice Hany
- Maurovich-Horvat Pál
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- Mayoraz Matias
- Mcalindon Elisa
- Mckenna Michael
- Mcrae Tony
- Medakovic Petar
- Medeiros Fábio
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- Meehan Conor
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- Mele Anibal
- Mendoza Fernando
- Meneghetti José Claudio
- Menezes de Siqueira Maria Eduarda
- Menezes Leon
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- Merani Maria Fernanda
- Meretta Alejandro Horacio
- Merhige Michael
- Mesquita Cláudio Tinoco
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- Min David
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- Modiselle Moshe
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- Moncayo Antonio Calderón
- Moncayo Antonio Calderón
- Moncher Karen
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- Mor Maya
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- More Stuart
- Morelos Martha
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- Morgan-Hughes Gareth
- Morimoto Ryota
- Moroi Masao
- Morozova Olga
- Morris Michael
- Moss Alastair
- Mossa-Basha Mahmud
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- Murphy Mark
- Murray Anthony
- Murray John
- Murthy Venkatesh
- Murton Fiona
- Muskal Noam
- Mut Fernando
- Muyinda Zerida
- Muñoz Gabriel Castro
- Mykhalchenko Olena
- Myo Khin Pa
- Nabil Sherif
- Nagamachi Shigeki
- Nagpal Prashant
- Naidoo Mathava
- Nailli Qais
- Nakajima Kenichi
- Nakata Tomoaki
- Nakazato Ryo
- Namgung Chang Kyeong
- Nanasato Mamoru
- Nanayakkara Damayanthi
- Nandurkar Dee
- Naojee Ambedhkar Shantaram
- Napier Kyle
- Nardi Barbara
- Narula Jagat
- Narula Jagat
- Naseer Hamid
- Nasery Mohammad Nawaz
- Naue Vania
- Naves Danilo
- Naya Masanao
- Neill Johanne
- Nelson Katarina
- Ng Ming Yen
- Nguyen Xuan Canh
- Nicol Edward
- Nieves A López De Munaín Maria
- Nijjar Prabhjot
- Nogueira Ramos Rodrigo Rizzo
- Noguera Eduardo
- Nolasco Roberto
- Nomura Cesar
- Norgaard Bjarne Linde
- Norikane Takashi
- Norton Carolina Bas
- Novoa Carlos
- Nunura Felix
- Nørgaard Bjarne Linde
- O'Brien Julie
- O'Rourke Edward
- O'Sullivan Patricia
- Obaldo Jerry
- Occleshaw Christopher
- Ohta Yasutoshi
- Oikonomou Anastasia
- Okarvi Subhani
- Okayama Satoshi
- Okizaki Atsutaka
- Oliveira Joao Bruno
- Ombati Kevin
- Onimode Yetunde
- Ornelas Mario
- Ortellado José
- Ortga Ramirez Jose Alberto
- Osman Medhat
- Otomi Yoichi
- Otsuka Hideki
- Ozair Ahmad
- Paar Maja Hrabak
- Pabon Luz
- Pacella Sara
- Padma Savenadia
- Paez Diana
- Paez Diana
- Paixao Eduardo
- Panagidis Christoforos
- Pandos George
- Parwani Purvi
- Parwani Purvi
- Parwani Purvi
- Pascual Thomas N. B.
- Pascual Thomas N. B.
- Pasquet Agnès
- Passen Edward
- Pastrana Davidson
- Patel Amit
- Patel Chetan
- Patel Dilip
- Patel Ravi
- Patel Shivani
- Patel Tapan
- Pathmaraj Kunthi
- Patil Pravin
- Paul Ryan
- Pawhay Christian Michael
- Pedras Felipe Villela
- Peebles Charles
- Peiro Virginia
- Peix Amalia
- Pepe Giovanna
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- Persic Viktor
- Petrou Ioannis
- Phillips Lawrence
- Pianta Diego Bromfman
- Picard Christian
- Pineda Mauricio
- Pinto Ibraim
- Pitman Alexander
- Pliatsek Volodymyr
- Poksi Anne
- Pollono Pablo
- Polsani Venkateshwar
- Poludasu Rajaram
- Pomerantz Brian
- Pontone Gianluca
- Pool Stefan
- Porter Thomas
- Pospelov Viktor
- Possetti Priscila
- Poulter Rohan
- Prawiro Djoko
- Preciado-Anaya Andrés
- Preciado-Gutiérrez Óscar Ulises
- Premaratne Manuja
- Premprabha Teerapon
- Prentice Ryan
- Prior David
- Prior John O.
- Probst Stephan
- Proffit Franck
- Prpic Marina
- Pubul-Nuñez Virginia
- Pugliese Francesca
- Pujol Maria Paula
- Pulizzi Sabina
- Punda Ante
- Pursnani Amit
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- Pynda Yaroslav
- Quartuccio Natale
- Quinon Alvin
- Quinta Mayra
- Rabbat Mark
- Radzinschi Alejandro
- Raggi Paolo
- Raggi Paolo
- Raimondi Gustavo
- Rajbanshi Bijoy
- Rajvong Sonexay
- Ramamurti Suresh
- Ramkumar Prasad Guntur
- Rampin Lucia
- Ramírez Nelsy Gonzalez
- Randazzo Michael
- Randazzo Michael J.
- Ranser Sara
- Rawashdeh Mohammad
- Rayo Madrid Juan Ignacio
- Redruello Marcela
- Regaieg Hamza
- Reichmuth Luise
- Repasos Evangelos
- Rey Cristina Rodríguez
- Riaz Musab
- Ricci Fabrizio
- Rich Florence
- Ridley Lloyd
- Robinson Austin
- Robles Kim
- Rocha Ricardo
- Rochela Luis
- Rodrigues Alfredo
- Rodrigues Carlos
- Rodriguez Daniel Calderon
- Rodríguez Cesar
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- Rodríguez Matías
- Roelants Veronique
- Rofe Christopher
- Roifman Idan
- Rojas Juan Carlos
- Romantini Leila
- Romero Romina Lorena
- Rominger Axel
- Roque Vanegas Hector Bladimir
- Rorie Mark
- Rosales Uvera Sandra Graciela
- Rossini Pierluigi
- Rostami Maryam Tajik
- Rovaletti Federico
- Rozikhodjaeva Gulnora
- Rubini Giuseppe
- Ruiz Diego
- Ruiz Joaquín
- Rumberger John
- Russell Raymond
- Russo Vincenzo
- Rutherford Natalie
- Ryzhkova Daria
- Ríos Raúl Araujo
- Rønnow Sand Niels Peter
- Saadullah Mohammad
- Sabharwal Nikant
- Sabra Philip
- Sacchetti Gian Mauro
- Sadler Diego
- Saifullina Guzaliya
- Saito Masaki
- Sakanyan Mari
- Sakata Sakata Yasushi
- Salehi Hamid
- Salobir Barbara Gužic
- Sambuceti Gianmario
- Samuel Anthony
- San Miguel Lucas
- Sanches Adelina
- Sandoval Sigelinda
- Santana Sara
- Sara da Silva Leonardo
- Sarai Masayoshi
- Saranovic Dragana Sobic
- Sarda-Mantel Laure
- Sasse Alexander
- Sato Daisuke
- Satyr Maryna
- Saunders Connor
- Saxena Sudhir
- Sayman Haluk
- Sazonova Svetlana
- Scarano Massimo
- Scarlett Luke
- Schemmer Mary
- Schmidt Erzsébet
- Schneider Roman P.
- Schoepf U. Joseph
- Schofield Rebecca
- Scholte Arthur
- Scholtens Asbjørn
- Scholtz Leonie
- Schvartzman Paulo
- Sciagrà Roberto
- Sebikali Mugisha Julius
- Sekar Ramkumar
- Sellem Ali
- Semple Thomas
- Seneviratne Sujith
- Sengupta Shantanu
- Senra Tiago
- Sereegotov Erdenechimeg
- Sergienko Vladimir
- Sergienko Vladimir
- Sevilla Ana
- Shaaban Mahmoud
- Shah Nishant
- Shah Nishant R.
- Shah Samir
- Shalev Aryeh
- Shanbhag Sujata
- Sharma Gaurav
- Sharma Naveen
- Shaw Leslee J.
- Shaw Leslee J.
- Shayani Steven
- Shetty Deepa
- Shiozaki Afonso
- Shiraishi Shinya
- Shirani Jamshid
- Shirka Ervina
- Shivaram Pushpa
- Shrestha Ganesh
- Shulman Jonathan
- Shurupova Irina
- Sierra-Galan Lilia M.
- Sierra-Galan Lilia M.
- Sigman Steven
- Silva Fábio Martins
- Simanek Milan
- Simon Mitch
- Simonsson Magnus
- Singh Bhanupriya
- Singh Santosh
- Sinitsyn Valentin
- Siqueira Cristiano
- Siu Silvia
- Slart Riemer
- Slim Ahmad
- Small Gary
- Smanio Paola
- Smith Alexandra
- Smith David
- So Young
- Soares Carlos Eduardo
- Soeriadi Erwin Affandi
- Solanki Vijay
- Solari Lucrecia
- Soldat-Stankovic Valentina
- Soli Idrissa Adamou
- Soman Prem
- Sood Aditya
- Sood Ashwani
- Sperandio Massimiliano
- Spiro Bernardo
- Srichai-Parsia Monvadi Barbara
- Stan Claudiu Adrian
- Stankovic Sinisa
- Stanton Tony
- Stavrou Petros
- Stefanelli Antonella
- Steffensen Rolf
- Strada Bruno
- Streeter James
- Strouhal Peter
- Stuart Murch
- Stubbs Michael
- Subedi Deepak
- Sueldo Claudio Pereyra
- Sun Kai
- Suwa Yoshinobu
- Swainson Ian
- Syawaluddin Hilman
- Syed Ghulam
- Szilveszter Balint
- T Albert
- Tacher Vania
- Tag Naima
- Takanami Kentaro
- Takehana Kazuya
- Taki Junichi
- Taleb Sara
- Tamaki Nagara
- Tandon Vikas
- Tang Gongshun
- Tang Jeanelle Margareth
- Taniguchi Yasuyo
- Taubman Kim
- Tawakol Ahmed
- Taylor Andrew
- Tecson Bettina
- Teragawa Hiroki
- Theng Youdaline
- Thientunyakit Tanyaluck
- Thimister Paul
- Thomas Dustin
- Thomas Paul
- Thomassen Anders
- Thompson Randall
- Thu Phyo Si
- To Andrew
- Tomas Miguel Santaularia
- Tomizawa Nobuo
- Topping William
- Torbet Tara
- Torreao Jorge
- Torres Rafael
- Traverso Sonia
- Traverzo Sonia Simona
- Trifonova Tatjana
- Trinidad Desiree
- Trivedi Adwait
- Tsujita Kenichi
- Tweed Katharine
- Udugama Chandraguptha
- Uellendahl Marly
- Ullery Shawn
- Umeji Kyoko
- Unger Steven
- Unzek Samuel
- Upton Anthony
- Uretsky Seth
- Uson Kristine Joy
- Ussov Wladimir Yurievich
- Uusitalo Valtteri
- Uy Mila
- Vajauskas Donatas
- Vakhromeeva Margarita
- Valiullina Nailya
- Vallejo Enrique
- Valles Mario
- Vallurupalli Srikanth
- Vallée Jean-Paul
- Valsamaki Pipitsa
- Vamadevan Shankar
- Van Asperen Erik-Jan
- Van De Heyning Caroline M.
- Van Gaal William
- Van Pelt Niels
- Vangu Mboyo
- Vargas Luis Salazar
- Vasquez Andres
- Vavlukis Marija
- Velez Mayra Sanchez
- Veltman Niels
- Ventroni Guido
- Vergel Damiana
- Verjans Johan
- Verma Atul
- Verma Vikas
- Verschure Derk
- Veríssimo Otávia
- Villines Todd C.
- Villines Todd C.
- Vitola Joao V.
- Vitola Joao V.
- Vondrak Andrej
- Voutnis Demetrius
- Vuuren Magritha Jv
- Várady Edit
- Vázquez Manuel Castillo
- Wagenaar Nils
- Wakabayashi Yasushi
- Waller Alfonso
- Waltrick Roberto
- Wang Ellen
- Wang Jian
- Wang Ximing
- Wang Yifan
- Wang Yining
- Wang Zhao-Qian
- Ward Parker
- Wayne Victor
- Weihmuller Juan Sebastian
- Weir-Mccall Jonathan
- Weiss Konrad
- Weissman Gaby
- Wesbey George
- White James
- White Kelly
- Williams Michelle C.
- Williams Michelle C.
- Wilson Peter
- Winchester David
- Winchester David
- Wolcan Juan
- Wolinsky David
- Won Kyoung Sook
- Wong David
- Wong Kirby
- Wu Jiang
- Wu Zhifang
- Xia Liming
- Xiao Jiangxi
- Xu Lei
- Xu Zhuoran
- Yamada Shinichiro
- Yamazaki Shinya
- Yang Youyou
- Yew Min Sen
- Yin Wu
- Yoneyama Tatsuya
- Yost Sandra
- Young Calum
- Younger John
- Younis Muhammad Numair
- Yu Jianqun
- Yuan Li
- Zaid Eed Abu
- Zakavi Seyed Rasoul
- Zapparoli Marcello
- Zavadovsky Konstantin
- Zeffiro Susana
- Zeidán Nahla
- Zerahn Bo
- Zgaljardic Michael
- Zhang Longjiang
- Zhang Tong
- Zhang Xiaoli
- Zhang Yong-Gao
- Zhu Li
- Zhuravlev Kirill
- Zoboli Stefania
- Zukotynski Katherine
- Zuluaga Alejandro
- Øvrehus Kristian Altern
- Štalc Monika
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2021
- Field of study
Objectives: This study sought to quantify and compare the decline in volumes of cardiovascular procedures between the United States and non-US institutions during the early phase of the coronavirus disease-2019 (COVID-19) pandemic.
Background: The COVID-19 pandemic has disrupted the care of many non-COVID-19 illnesses. Reductions in diagnostic cardiovascular testing around the world have led to concerns over the implications of reduced testing for cardiovascular disease (CVD) morbidity and mortality.
Methods: Data were submitted to the INCAPS-COVID (International Atomic Energy Agency Non-Invasive Cardiology Protocols Study of COVID-19), a multinational registry comprising 909 institutions in 108 countries (including 155 facilities in 40 U.S. states), assessing the impact of the COVID-19 pandemic on volumes of diagnostic cardiovascular procedures. Data were obtained for April 2020 and compared with volumes of baseline procedures from March 2019. We compared laboratory characteristics, practices, and procedure volumes between U.S. and non-U.S. facilities and between U.S. geographic regions and identified factors associated with volume reduction in the United States.
Results: Reductions in the volumes of procedures in the United States were similar to those in non-U.S. facilities (68% vs. 63%, respectively; p = 0.237), although U.S. facilities reported greater reductions in invasive coronary angiography (69% vs. 53%, respectively; p < 0.001). Significantly more U.S. facilities reported increased use of telehealth and patient screening measures than non-U.S. facilities, such as temperature checks, symptom screenings, and COVID-19 testing. Reductions in volumes of procedures differed between U.S. regions, with larger declines observed in the Northeast (76%) and Midwest (74%) than in the South (62%) and West (44%). Prevalence of COVID-19, staff redeployments, outpatient centers, and urban centers were associated with greater reductions in volume in U.S. facilities in a multivariable analysis.
Conclusions: We observed marked reductions in U.S. cardiovascular testing in the early phase of the pandemic and significant variability between U.S. regions. The association between reductions of volumes and COVID-19 prevalence in the United States highlighted the need for proactive efforts to maintain access to cardiovascular testing in areas most affected by outbreaks of COVID-19 infection
Finishing the euchromatic sequence of the human genome
- Author
- . Haifeng
- . Magner
- . Yin
- Abbott Scott
- Abbott-Ozersky Amanda
- Abdellah Zahra
- Abouelleil Amr
- Abrajano Anne
- Adachi Tamami
- Adam Catherine
- Adams Charles Q.
- Adamson Aaron
- Adekoya Emmanuel
- Adio-Oduola Babajide
- Aerts Andrea
- Aggarwal Arun
- Ahmadi Alireza
- Ahmed Shahana
- Aimable Matthew
- Ainscough Rachael
- Ait-Zahra Mostafa
- Aizu Tomoyuki
- Alcivare Dana
- Alegria Michelle
- Ali Alla
- Ali Johar
- Allegria-hartmann Michelle
- Alleman Jennifer
- Allen Carlana C.
- Allen Heather
- Allen Nicole R.
- Allen Susan
- Allen Thaddeus
- Almeida Jeff
- Almond Claire
- Alsbrooks Stephen L.
- Altherr Michael R.
- Amaratunge Harshinie C.
- Ambler Andrew
- Ambrose Karen
- Ambrose Kerrie
- Amemiya Chris
- Amico-Keller Gina
- Amin Amita G.
- Anderson Mechele
- Anderson Scott
- Anderson Scott
- Andora Janice
- Andredesz Carol
- Andrew Robert
- Andrews Dan
- Andrews Daniel
- Andrews Neil
- Andrews Stephanie
- Andriese Tim
- Anthouard Véronique
- Antonarakis Stylianos E.
- Anyalebechi Vivian
- Aoki Norie
- Apostolou Sinoula
- Apweiler Eva
- Arachchi Harindra
- Arai Rie
- Arbery Hazel
- Arcaina Marlon
- Arcaina Terisita
- Archer Beth
- Arellano Andre
- Arellano-Jones Perry
- Armbruster Jeff
- Armstrong Jon
- Arredondo Dilrukshi P.
- Arredondo Heather Hope
- Artiguenave François
- Asakawa Shuichi
- Asakawa Teruyo
- Ash Gareth
- Ashcroft Kevin
- Ashurst Jennifer
- Ashwell Robert
- Ashworth Linda K.
- Aslanidis Cara
- Asomugha Chinwe O.
- Asuncion Lawreen
- Atkin Deborah
- Atkinson Andrea
- Atkinson Barry
- Attix Cristina
- Attwood John
- Aubin Keith
- Auger Katherine
- Austin Shannon Michelle
- Avila Aaron
- Avis Terry
- Ayele Mulu
- Babayan Primo
- Babbage Anne
- Babbage Sarah
- Bach Phil
- Bachatsang Pasang
- Bacon Joanne
- Badri Hummy
- Baertsch Robert
- Bagguley Claire
- Bailey Jonathan
- Bajorek Eva
- Baker Andrew
- Baker Dan
- Baker M.
- Baker Richard
- Bakis Michele
- Baldwin Jennifer
- Banda Michael
- Banerjee Ruby
- Bao Jingyue
- Bao Qiyu
- Bao Weidong
- Bao Weidong
- Baptiste Pertrice
- Barbaria Joseph A.
- Barbe Valérie
- Bardill Simon
- Barker Daniel
- Barker Darren
- Barker Gary
- Barlow Karen
- Baron Laurent
- Barrett Anika
- Bartlett Rebecca
- Basham Victoria
- Bashman David
- Basu Suba
- Bateman Alex
- Bates Karen
- Battles John
- Batzer Mark
- Baumgart Cornelia
- Baumohl Jason
- Baynes Caroline
- Bayul Tashi
- Beall Keith
- Beard Lisa
- Beard Susan
- Beare David
- Beasley Alastair
- Beasley Helen
- Beasley Oliver
- Beaucham Leslie
- Beaudet Arthur
- Beck Alfred
- Beck Stephen
- Becker Michael
- Bell Emma
- Bell George I.
- Bellard Terell M.
- Bellerby Damian
- Bellerby Tristram
- Belter Edward A., Jr.
- Bemrose Richard
- Benard Michael Anthony
- BenKahla Alia
- Benke J
- Benner William
- Bennett James
- Bensasson Douda
- Bentley Andrew
- Bentley Dan
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- Lou Yunian
- Loulseged Hermela
- Loveland Jane
- Lovell Jamie
- Lovett Demetria A.
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- Lowry Stephen
- Lozado Ryan J.
- Lu Lingfeng
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- Lucier Raymond L.
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- MacLean Christine
- Madabhushi Ramki
- Madu Renita C.
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- Wu Kevin
- Wu Qingfa
- Wu Qingfa
- Wu Ruiming
- Wu Xiao
- Wu Xiaojing
- Wu Zaining
- Wyatt Julia
- Wycoff-Montenegro Melissa
- Wylie Kris
- Wyman Dudley
- Wyman Stacia
- Xi Yan
- Xi Yingying
- Xie Fei
- Xie Gary
- Xie Jane
- Xiong Hui
- Xiong Yuqing
- Xu Alex
- Xu Jing
- Xu Jing
- Xu Ruqin
- Xu Shuhua
- Xu Wei
- Xu Xinlai
- Xu Yan
- Xu Yuning
- Xu Zhihong
- Xu Zuyuan
- Xuan Yali
- Xuan Zhenyu
- Xue Rui
- Yada Tetsushi
- Yadav Shailendra
- Yakub Syed
- Yamamoto Lynn
- Yamamoto Noriko
- Yamamoto Yuko
- Yamashita Yasue
- Yamazaki Satoru
- Yang Hao
- Yang Huanming
- Yang Huanming
- Yang Joan
- Yang Shiaw-Pyng
- Yang Shudong
- Yang Xiaonan
- Yang Xiaonan
- Yang Xiaoping
- Yang Yongkui
- Yano Candance
- Yao Zhijian
- Yao Zhijian
- Yaspo Marie-Laure
- Ye Chen
- Yeager Shane
- Yeh Mimi
- Yen Jennifer
- Yeshitela Rahel Retta
- Yoakum Martin
- Yokobata Kathy
- Yokoyama Jennifer
- Yonezawa Miho
- Yoon Lillienne
- Yoon Vivienne
- Yoshida Satoru
- You Bo
- Young Geneva
- Young Louise
- Young Shelia
- Younger Ruth
- Yu Bing
- Yu Charles
- Yu Fuli
- Yu Jun
- Yu Jun
- Yu Jun
- Yuan Kaiwen
- Yuan Ye
- Yuan Yida
- Yue Shujie
- Yumae Brian
- Yun Rui
- Zainoun Joanne
- Zembeck Lisa
- Zeng Yixin
- Zhai Dong
- Zhan Guoping
- Zhang Bo
- Zhang Caimin
- Zhang Fengmei
- Zhang Guangyu
- Zhang Guohua
- Zhang Guohua
- Zhang Haiqing
- Zhang Haiqing
- Zhang Haiqing
- Zhang Hongbo
- Zhang Hongbo
- Zhang Jingjing
- Zhang Jingjing
- Zhang Jingkun
- Zhang Jiuchun
- Zhang Jiuchun
- Zhang Lanzhi
- Zhang Li
- Zhang Li
- Zhang Meihua
- Zhang Meng
- Zhang Ming
- Zhang Qing
- Zhang Ruhua
- Zhang Shaojie
- Zhang Tiezhen
- Zhang Wei
- Zhang Wei
- Zhang Xianglin
- Zhang Xianglin
- Zhang Xiaoliang
- Zhang Xiuqing
- Zhang Yan
- Zhang Yi
- Zhang Yilin
- Zhang Yilin
- Zhang Ying
- Zhang Yuansen
- Zhang Yuzhi
- Zhang Zhengdong
- Zhao Hongmei
- Zhao Lijian
- Zhao Shenru
- Zhao Zhijing
- Zhen Zhicheng
- Zheng Haibo
- Zhong Ming
- Zhou Carol
- Zhou Haixia
- Zhou Jianling
- Zhou Nannan
- Zhou Xinfeng
- Zhou Yan
- Zhou Yang
- Zhou Yi
- Zhu Bingying
- Zhu Bofeng
- Zhu Fenghua
- Zhu Genfeng
- Zhu Genfeng
- Zhu Miao
- Zhu Ning
- Zhu Yongge
- Zhu Zhen
- Zhuang Shitao
- Zierten Deborah
- Zimmer Andrew
- Zody Michael C.
- Zollo Massimo
- Zorrilla Sara E.
- Zuo Lin
- Publication venue
- LSU Digital Commons
- Publication date
- 21/10/2004
- Field of study
The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function.
- Author
- Aaron Folsom
- Aaron Isaacs
- Abbas Dehghan
- Adebowale Adeyemo
- Adrienne Tin
- Afshin Parsa
- Aida Karina Dieffenbach
- Alan B. Weder
- Alan B. Zonderman
- Alan F. Wright
- Alan Go
- Alan R. Shuldiner
- Alanna C. Morrison
- Albert Hofman
- Albert V. Smith
- Albert W. Dreisbach
- Alena Stancakova
- Alex N. Parker
- Alexander Teumer
- Alexandre F. R. Stewart
- Alistair Hall
- Amy J. Swift
- Anders Hamsten
- Andre Franke
- Andre G. Uitterlinden
- Andreas Meinitzer
- Andreas Tomaschitz
- Andreas Ziegler
- Andres Metspalu
- Andrew A. Hicks
- Andrew D. Johnson
- Andrew Plump
- Andrew Singleton
- Andrew Taylor
- Andrew Wong
- Angela Doering
- Angelo Scuteri
- Anika Grosshennig
- Anja Medack
- Anke Tonjes
- Anna F. Dominiczak
- Anna Köttgen
- Anna Maria Corsi
- Anna-Liisa Hartikainen
- Anne U. Jackson
- Annette Peters
- Annika Rosengren
- Anthony J. Balmforth
- Antonietta Robino
- Antonio Lupo
- Anuj Goel
- Aravinda Chakravarti
- Arne Schillert
- Arnika K. Wagner
- Aroon D. Hingorani
- Asif Rasheed
- Atsushi Takahashi
- Aude Saint-Pierre
- Audrey Y. Chu
- Augustine Kong
- Augusto D. Pichard
- Ayo Doumatey
- Ayse Demirkan
- Bamidele Tayo
- Barbara Kollerits
- Barbara Ludwig
- Barry I. Freedman
- Belen Ponte
- Ben A. Oostra
- Benedicte Stengel
- Benjamin F. Voight
- Benjamin J. Wright
- Bernhard K. Krämer
- Bernhard O. Böhm
- Bernhard Paulweber
- Bernhard R. Winkelmann
- Bo Hedblad
- Bok-Ghee Han
- Braxton D. Mitchell
- Brenda W. Penninx
- Brendan M. Buckley
- Bruce M. Psaty
- Bruno H. Stricker
- Candace Guiducci
- Carl D. Langefeld
- Carl G. P. Platou
- Carlos Iribarren
- Carmen A. Peralta
- Carole Proust
- Caroline Hayward
- Caroline S. Fox
- Carsten A. Böger
- Catherine Helmer
- Charles N. Rotimi
- Charles S. Janipalli
- Chien-Hsiun Chen
- Chittaranjan S. Yajnik
- Christa Meisinger
- Christian Fuchsberger
- Christian Gieger
- Christian Hengstenberg
- Christian M. Shaffer
- Christian Müller
- Christina Loley
- Christina Willenborg
- Christoph Bickel
- Christoph Sinning
- Christopher J. O’Donnell
- Christopher Newton-Cheh
- Christopher P. Nelson
- Christopher W. Knouff
- Cinzia Sala
- Claire Perret
- Colin A. McKenzie
- Cornelia M. van Duijn
- Cristian Pattaro
- Cristiano Fava
- Cuno S. P. M. Uiterwaal
- D. G. Vinay
- Dabeeru C. Rao
- Daehee Kang
- Dag S. Thelle
- Dan E. Arking
- Daniel Ackermann
- Daniel I. Chasman
- Daniel J. Rader
- Daniel Levy
- Daniel Shriner
- Daniel Taliun
- Daniela Ruggiero
- Daniela Toniolo
- Daniele Cusi
- Danish Saleheen
- Darina Czamara
- David Altshuler
- David Couper
- David Ellinghaus
- David Hadley
- David P. Strachan
- David S. Siscovick
- Dawn M. Waterworth
- Debbie A. Lawlor
- Dena Hernandez
- Devin Absher
- Diana Kuh
- Diana Zelenika
- Diederick E. Grobbee
- Dongfeng Gu
- Donna K. Arnett
- Dorairajan Prabhakaran
- Douglas Ruderfer
- E-Shyong Tai
- Edward G. Lakatta
- Elena Rochtchina
- Elin Org
- Elizabeth G. Holliday
- Elizabeth J. Atkinson
- Emelia Benjamin
- Eran Halperin
- Eric Boerwinkle
- Eric J. G. Sijbrands
- Erik Ingelsson
- Erika Salvi
- Erkki Vartiainen
- Ervin R. Fox
- Erwin P. Bottinger
- Eva Albrecht
- Eva Brand
- Ewa Zukowska-Szczechowska
- F. Gerald R. Fowkes
- Fadi J. Charchar
- Federico Murgia
- Feng Zhang
- Fernando Rivadeneira
- Florian Ernst
- Florian Kronenberg
- Francesco U. S. Mattace-Raso
- Francis S. Collins
- Francois Cambien
- Frank B. Hu
- Fredrik Nyberg
- Fulvio Ricceri
- Fumihiko Takeuchi
- Fuu-Jen Tsai
- Gang Shi
- Gary C. Curhan
- Gary F. Mitchell
- Gavin Lucas
- Georg Homuth
- George A. Wells
- George B. Ehret
- George Davey Smith
- Gerjan J. Navis
- Germaine C. Verwoert
- Gian-Andri Thun
- Gina Hilton
- Giorgio Pistis
- Giovanni Gambaro
- Giovanni Malerba
- Giriraj R. Chandak
- Giuseppe Matullo
- Goncalo R. Abecasis
- Grant W. Montgomery
- Guangju Zhai
- Gudmar Thorleifsson
- Gudmundur Thorgeirsson
- Gudny Eiriksdottir
- Gudrun Veldre
- Gunnar Jacobs
- Guo Li
- H-Erich Wichmann
- Haidong Zhu
- Hakon H. Hakonarson
- Halit Ongen
- Hans J. Rupprecht
- Hao Mei
- Harald Dobnig
- Harald Grallert
- Harold Snieder
- Harry Campbell
- Heather M. Stringham
- Helena Schmidt
- Henri Wallaschofski
- Henry Völzke
- Heribert Schunkert
- Hermann Brenner
- Heyo K. Kroemer
- Hilma Holm
- Hirotsugu Ueshima
- Holly Kramer
- Honghuang Lin
- Hua Tang
- Hubert Scharnagl
- Hugh Watkins
- Hyung-Lae Kim
- I. Mateo Leach
- Ian Ford
- Ian H. de Boer
- Ian N. M. Day
- Ida Yii-Der Chen
- Idris Guessous
- Iftikhar Kullo
- Igor Rudan
- Ilja M. Nolte
- Ines Barroso
- Inga Prokopenko
- Ingrid Borecki
- Inke R. König
- Ioanna Tzoulaki
- Iris M. Heid
- Ivana Kolcic
- Ivana Persico
- J. H. Young
- J. Wouter Jukema
- Jaakko Tuomilehto
- Jaana Laitinen
- Jaap W. Deckers
- Jackie A. Cooper
- Jacqueline C. M. Witteman
- Jacques S. Beckmann
- James E. Hixson
- James F. Meschia
- James F. Wilson
- James Scott
- James T. Willerson
- Jan A. Staessen
- Jan Stritzke
- Janine F. Felix
- Janja Nahrstedt
- Janos Terzic
- Jasmin Divers
- Jaspal S. Kooner
- Jayashri Aragam
- Jean-Charles Lambert
- Jean-Michel Gaspoz
- Jeanette Erdmann
- Jeanette M. Stafford
- Jeffrey R. Gulcher
- Jeffrey R. O’Connell
- Jemma C. Hopewell
- Jennifer A. Smith
- Jennifer L. Bragg-Gresham
- Jer-Yuarn Wu
- Jerome I. Rotter
- Jessica D. Faul
- Jiang He
- Jianjun Liu
- Jian’an Luan
- Jie Jin Wang
- Jie Yao
- Jing Hua Zhao
- Jingzhong Ding
- Joanne Murabito
- Joban S. Sehmi
- Joe Devaney
- Joel N. Hirschhorn
- Johanna Kuusisto
- Johanne Tremblay
- Johannes H. Smit
- Johannes Haerting
- John Attia
- John B. Whitfield
- John C. Chambers
- John Chalmers
- John Danesh
- John F. Peden
- John M. Connell
- John P. Beilby
- John R. Thompson
- John S. Gottdiener
- Jong-Young Lee
- Jorma Viikari
- Josef Coresh
- Joseph M. Lindsay
- Joshua C. Bis
- Joshua C. Denny
- Joshua Knowles
- Juan P. Casas
- Judith A Hoffman Bolton
- Juha Karjalainen
- Jutta Palmen
- Jyotika K. Fernandes
- Jürgen Grässler
- K. Radha Mani
- Karen L. Mohlke
- Kari Stefansson
- Karin Halina Greiser
- Karl Andersen
- Karl J. Lackner
- Karl Werdan
- Karl Winkler
- Karlhans Endlich
- Katalin Susztak
- Katja Butterbach
- Kay-Tee Khaw
- Kazuhiko Yamamoto
- Keith L. Keene
- Kelly Volcik
- Kenneth M. Kent
- Kenneth M. Rice
- Kent D. Taylor
- Kerri L. Wiggins
- Khanh-Dung Hoang Nguyen
- Kiran Musunuru
- Klaus Stark
- Kristian Hveem
- Kristin Marciante
- Kurt Lohman
- L. Adrienne Cupples
- Lars Lind
- Laura J. Scott
- Laura Portas
- Laura R. Loehr
- Laurence Tiret
- Leena Peltonen
- Leif Groop
- Lenore J. Launer
- Leo-Pekka Lyytikäinen
- Leslie J. Raffel
- Li Chen
- Li-Ching Chang
- Liming Qu
- Linda S. Adair
- Loic Yengo
- Lori L. Bonnycastle
- Louise V. Wain
- Lowell Satler
- Lude Franke
- Luigi Ferrucci
- Lyle J. Palmer
- Lynda M. Rose
- Lynne E. Wagenknecht
- Lyudmyla Kedenko
- M. Arfan Ikram
- M. J. Kranthi Kumar
- Maciej Tomaszewski
- Madhumathi Rao
- Maija Garnaas
- Maja Barbalic
- Maksim Struchalin
- Man Li
- Manuela Uda
- Marco Orru
- Marcus Dörr
- Marcus E. Kleber
- Marcus Fischer
- Margaret M. Redfield
- Margherita Cavalieri
- Margot Haun
- Margus Viigimaa
- Maria Blettner
- Maria Soler Artigas
- Marie Metzger
- Marilyn C. Cornelis
- Marina Ciullo
- Mario A. Morken
- Mario Pirastu
- Maris Laan
- Mariza de Andrade
- Marjo-Riitta Jarvelin
- Mark A. McEvoy
- Mark Hlatky
- Mark J. Caulfield
- Mark Lathrop
- Mark Seielstad
- Mark Woodward
- Marketa Sjögren
- Markku Laakso
- Markus Perola
- Martin Adam
- Martin D. Tobin
- Martin Farrall
- Martin G. Larson
- Mary F. Feitosa
- Mary Susan Burnett
- Masato Isono
- Massimiliano Cocca
- Massimo Mangino
- Mathias Gorski
- Matthew Denniff
- Matthew N. Cooper
- Matthias Nauck
- Matthias Olden
- Max C. Walker
- Medea Imboden
- Meena Kumari
- Megan E. Rudock
- Melanie Waldenberger
- Melissa Garcia
- Menno Pruijm
- Meredith Foster
- Michael Boehnke
- Michael G. Marmot
- Michael M. Hoffmann
- Michael Nalls
- Michael Preuss
- Michael Stumvoll
- Michele K. Evans
- Michele M. Sale
- Michiaki Kubo
- Michiel L. Bots
- Mika Kivimaki
- Mika Kähönen
- Min Jin Go
- Ming-Huei Chen
- Mingyao Li
- Mladen Boban
- Morris J. Brown
- Muhammad Islam
- Muredach P Reilly
- Murielle Bochud
- Myriam Alexander
- Myriam Rheinberger
- N. Charlotte Onland-Moret
- Nabila Bouatia-Naji
- Najaf Amin
- Nanette I. Steinle
- Nanette R. Lee
- Naoharu Iwai
- Naoyuki Kamatani
- Narisu Narisu
- Neil Risch
- Nele Friedrich
- Nicholas G. Martin
- Nicholas J. Wareham
- Nicholas L. Smith
- Nicholette D. Palmer
- Nick Hastie
- Nick R. G. Shrine
- Nicole L. Glazer
- Nicole Probst-Hensch
- Nicole Soranzo
- Niek Verweij
- Nilesh J. Samani
- Nish Chaturvedi
- Noel Burtt
- Norbert Watzinger
- Norihiro Kato
- Norman Klopp
- null null
- null null
- null null
- null null
- null null
- Olga Jarinova
- Olivier Devuyst
- Olle Melander
- Olli Raitakari
- Omri Gottesman
- Oscar H. Franco
- Ozren Polasek
- Paavo Zitting
- Pankaj Arora
- Pankaj Sharma
- Panos Deloukas
- Paolo Gasparini
- Paolo Vineis
- Patricia B. Munroe
- Patricia P. Chang
- Patrick Diemert
- Patrick Linsel-Nitschke
- Paul Elliott
- Paul F. O’Reilly
- Paul M. Ridker
- Paul Mitchell
- Paul Muntner
- Paul R. Burton
- Pavel Hamet
- Peng Chen
- Peter E. H. Schwarz
- Peter H. Whincup
- Peter J. van der Most
- Peter Kovacs
- Peter Nilsson
- Peter P. Pramstaller
- Peter S. Braund
- Peter Vollenweider
- Petra Bruse
- Philip Howard
- Philipp S. Wild
- Philippa J. Talmud
- Philippe Froguel
- Pierre Meneton
- Pilar Galan
- Pim van der Harst
- Pio d’Adamo
- Qiong Yang
- Rainer Rettig
- Ramachandran S. Vasan
- Rebecca Hardy
- Reedik Mägi
- Reijo Laaksonen
- Reiner Biffar
- Reinhold Schmidt
- Renate Schnabel
- Richard J. Rodeheffer
- Richard Myers
- Richard N. Bergman
- Richard S. Cooper
- Richard W. Morris
- RickTwee-Hee Ong
- Rita P. S. Middelberg
- Robert Clarke
- Robert J. Carroll
- Robert Roberts
- Robert W. Lawrence
- Robert Wilensky
- Robert Zweiker
- Roberto Elosua
- Rodney J. Scott
- Ron Waksman
- Ronit Katz
- Rory Collins
- Rossella Sorice
- Ruth J. F. Loos
- Ruth McPherson
- S. -J. Cathy Fann
- Samer Najjar
- Sanaz Sedaghat
- Sanjay Kinra
- Santhi K. Ganesh
- Santosh Dahgam
- Sarah H. Wild
- Satoshi Umemura
- Sekar Kathiresan
- Serge Hercberg
- Serkalem Demissie-Banjaw
- Sharon L. R. Kardia
- Sheila Ulivi
- Shih-Jen Hwang
- Shiro Maeda
- Shufeng Chen
- Siim Sõber
- Simon Heath
- Simonetta Guarrera
- Smita R. Kulkarni
- Solveig Gretarsdottir
- Sonny Dandona
- Stacey B. Gabriel
- Stefan Blankenberg
- Stefan Coassin
- Stefan Enroth
- Stefan Kloiber
- Stefan Pilz
- Stefan R. Bornstein
- Stefan Schreiber
- Stefan-Martin Brand
- Stefania Bandinelli
- Stella Trompet
- Stephan B. Felix
- Stephan J. L. Bakker
- Stephen E. Epstein
- Stephen Fortmann
- Stephen G. Ball
- Stephen J. Hancock
- Stephen T. Turner
- Steve E. Humphries
- Steven C. Hunt
- Steven M. Schwartz
- Steven Sidney
- Su-Chi Lim
- Sudha Seshadri
- Sue Shaw-Hawkins
- Susan R. Heckbert
- Susana Eyheramendy
- Sven Bergmann
- Sylvia E. Rosas
- Sylvia Stracke
- Takayoshi Ohkubo
- Talin Haritunians
- Tamara B. Harris
- Tanja B. Grammer
- Tanja Zeller
- Tatiana Kuznetsova
- Tatijana Zemunik
- Tatjana Stojakovic
- Tatsuhiko Tsunoda
- Tazeen H. Jafar
- Terho Lehtimäki
- Terrence Forrester
- Terri L. Young
- Tetsuro Miki
- Themistocles L. Assimes
- Thomas F. Münzel
- Thomas H. Mosley
- Thomas Illig
- Thomas J. Wang
- Thomas Lumley
- Thomas Meitinger
- Thomas Quertermous
- Thor Aspelund
- Thorsten Reffelmann
- Tien-Yin Wong
- Tiit Nikopensius
- Tim D. Spector
- Timothy M. Frayling
- Tin Aung
- Toby Johnson
- Tom R. Gaunt
- Tomohiro Katsuya
- Tomonori Okamura
- Tonu Esko
- Toshihiro Tanaka
- Toshiko Tanaka
- Toshio Ogihara
- Tunde Salako
- Tune H. Pers
- Ulf Gyllensten
- Unnur Thorsteinsdottir
- Uwe Völker
- Valur Emilsson
- Vasyl Pihur
- Veikko Salomaa
- Veronique Vitart
- Vikal Tripathy
- Ville Aalto
- Vilmundur Gudnason
- Vincent Chouraki
- Vincent Mooser
- Viviane Nicaud
- Vladan Mijatovic
- W. H. Linda Kao
- Walter Palmas
- Wayne D. Rosamond
- Wei-Min Chen
- Weihua Zhang
- Wendy L. McArdle
- Wiek H. van Gilst
- Wilfried Renner
- Will T. Longstreth
- William Matthai
- Wilmar Igl
- Winfried März
- Wolfgang Koenig
- Wolfgang Lieb
- Wolfram Goessling
- Xiaofeng Zhu
- Xiaoling Wang
- Xiuqing Guo
- Xueling Sim
- Yali Li
- Yan V. Sun
- Yanbin Dong
- Yasuharu Tabara
- Yen-Pei C. Chang
- Yi-An Ko
- Yik-Ying Teo
- Ying A. Wang
- Ying Wu
- Yingchang Lu
- Yong Li
- Yongmei Liu
- Yoon Shin Cho
- Yoshikuni Kita
- Young Jin Kim
- Yuan-Tsong Chen
- Yukinori Okada
- Yuri Milaneschi
- Yurii Aulchenko
- Yusuke Nakamura
- Yvonne T. van der Schouw
- Zouhair Aherrahrou
- Åsa Johansson
- Publication venue
- Springer Nature America, Inc
- Publication date
- 27/10/2015
- Field of study
Reduced glomerular filtration rate defines chronic kidney disease and is associated with cardiovascular and all-cause mortality. We conducted a meta-analysis of genome-wide association studies for estimated glomerular filtration rate (eGFR), combining data across 133,413 individuals with replication in up to 42,166 individuals. We identify 24 new and confirm 29 previously identified loci. Of these 53 loci, 19 associate with eGFR among individuals with diabetes. Using bioinformatics, we show that identified genes at eGFR loci are enriched for expression in kidney tissues and in pathways relevant for kidney development and transmembrane transporter activity, kidney structure, and regulation of glucose metabolism. Chromatin state mapping and DNase I hypersensitivity analyses across adult tissues demonstrate preferential mapping of associated variants to regulatory regions in kidney but not extra-renal tissues. These findings suggest that genetic determinants of eGFR are mediated largely through direct effects within the kidney and highlight important cell types and biological pathways
Use of TEOAE, ABR, and Acoustic Reflex Measures to Assess Auditory Function Patients With Acoustic Neuroma
- Author
- Publication venue
- 'American Speech Language Hearing Association'
- Publication date
- Field of study
Preemergence Activity of Dinitroaniline herbicides Used for Weed Control in Cool-Season Turfgrasses
- Author
- Publication venue
- 'Cambridge University Press (CUP)'
- Publication date
- Field of study
Regulation of hmp
- Author
- Andrews S. C.
- Boerman S. J.
- Cramm R.
- Crawford M. J.
- Crawford M. J.
- Dikshit K. L.
- Dikshit R. P.
- Favey S.
- Garbe T. R.
- Gardner P. R.
- Gilles-Gonzalez M. A.
- Hausladen A.
- Hu Y. M.
- Ioannidis N.
- Khosla C.
- Kochi A.
- Mangan J. A.
- Membrillo-Hernández J.
- Membrillo-Hernández J.
- Membrillo-Hernández J.
- Mulvey M. R.
- Poole R. K.
- Poole R. K.
- Probst I.
- Sanger F.
- Smith D. T.
- Sudre P.
- Vasudevan S. G.
- Wakabayashi S.
- Wayne L. G.
- Wayne L. G.
- Wayne L. G.
- Zhao X. J.
- Publication venue
- 'American Society for Microbiology'
- Publication date
- Field of study
- …