493 research outputs found
Conserved metabolite regulation of stress granule assembly via AdoMet
- Publication venue
- 'Rockefeller University Press'
- Publication date
- 01/07/2020
- Field of study
© The Author(s), 2020. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Begovich, K., Vu, A. Q., Yeo, G., & Wilhelm, J. E. Conserved metabolite regulation of stress granule assembly via AdoMet. Journal of Cell Biology, 219(8), (2020): e201904141, doi:10.1083/jcb.201904141.Stress granules (SGs) are evolutionarily conserved condensates of ribonucleoproteins that assemble in response to metabolic stresses. Because aberrant SG formation is associated with amyotrophic lateral sclerosis (ALS), understanding the connection between metabolic activity and SG composition can provide therapeutic insights into neurodegeneration. Here, we identify 17 metabolic enzymes recruited to yeast SGs in response to physiological growth stress. Furthermore, the product of one of these enzymes, AdoMet, is a regulator of SG assembly and composition. Decreases in AdoMet levels increase SG formation, while chronic elevation of AdoMet produces SG remnants lacking proteins associated with the 5′ end of transcripts. Interestingly, acute elevation of AdoMet blocks SG formation in yeast and motor neurons. Treatment of ALS-derived motor neurons with AdoMet also suppresses the formation of TDP-43–positive SGs, a hallmark of ALS. Together, these results argue that AdoMet is an evolutionarily conserved regulator of SG composition and assembly with therapeutic potential in neurodegeneration.Work from the Wilhelm laboratory was supported by a grant to J.E. Wilhelm from the Collaborative Innovation Awards program of Howard Hughes Medical Institute and the James Wilhelm Memorial Fund. K. Begovich is a Howard Hughes Medical Institute Gilliam Fellow. Work from the Yeo laboratory was supported by grants to G. Yeo from the National Institutes of Health (HG004659), Target ALS (20193440), and the ALS Association (272 and 438)
Transcriptome-pathology correlation identifies interplay between TDP-43 and the expression of its kinase CK1E in sporadic ALS.
- Author
- Publication venue
- eScholarship, University of California
- Publication date
- 07/06/2018
- Field of study
Sporadic amyotrophic lateral sclerosis (sALS) is the most common form of ALS, however, the molecular mechanisms underlying cellular damage and motor neuron degeneration remain elusive. To identify molecular signatures of sALS we performed genome-wide expression profiling in laser capture microdissection-enriched surviving motor neurons (MNs) from lumbar spinal cords of sALS patients with rostral onset and caudal progression. After correcting for immunological background, we discover a highly specific gene expression signature for sALS that is associated with phosphorylated TDP-43 (pTDP-43) pathology. Transcriptome-pathology correlation identified casein kinase 1ε (CSNK1E) mRNA as tightly correlated to levels of pTDP-43 in sALS patients. Enhanced crosslinking and immunoprecipitation in human sALS patient- and healthy control-derived frontal cortex, revealed that TDP-43 binds directly to and regulates the expression of CSNK1E mRNA. Additionally, we were able to show that pTDP-43 itself binds RNA. CK1E, the protein product of CSNK1E, in turn interacts with TDP-43 and promotes cytoplasmic accumulation of pTDP-43 in human stem-cell-derived MNs. Pathological TDP-43 phosphorylation is therefore, reciprocally regulated by CK1E activity and TDP-43 RNA binding. Our framework of transcriptome-pathology correlations identifies candidate genes with relevance to novel mechanisms of neurodegeneration
Distinct and shared functions of ALS-associated proteins TDP-43, FUS and TAF15 revealed by multisystem analyses
- Author
- Ares Jr. Manuel
- Batra Ranjan
- Burge Christopher B
- Cambi Franca
- Chang Jeremy
- Chun Seung J.
- Donohue John P.
- Freese Peter Dale
- Hoon Shawn
- Huelga Stephanie C.
- Hutt Kasey R.
- Kapeli Katannya
- Kasarskis Edward
- Lambert Nicole
- Liang Tiffany Y.
- Martinez Fernando J.
- Pratt Gabriel A.
- Ravits John
- Rigo Frank
- Shiue Lily
- Sundararaman Balaji
- Vu Anthony Q.
- Yeo Gene W.
- Zhang Jiayu
- Zhu Haining
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/09/2015
- Field of study
The RNA-binding protein (RBP) TAF15 is implicated in amyotrophic lateral sclerosis (ALS). To compare TAF15 function to that of two ALS-associated RBPs, FUS and TDP-43, we integrate CLIP-seq and RNA Bind-N-Seq technologies, and show that TAF15 binds to ∼4,900 RNAs enriched for GGUA motifs in adult mouse brains. TAF15 and FUS exhibit similar binding patterns in introns, are enriched in 3′ untranslated regions and alter genes distinct from TDP-43. However, unlike FUS and TDP-43, TAF15 has a minimal role in alternative splicing. In human neural progenitors, TAF15 and FUS affect turnover of their RNA targets. In human stem cell-derived motor neurons, the RNA profile associated with concomitant loss of both TAF15 and FUS resembles that observed in the presence of the ALS-associated mutation FUS R521G, but contrasts with late-stage sporadic ALS patients. Taken together, our findings reveal convergent and divergent roles for FUS, TAF15 and TDP-43 in RNA metabolism.National Institutes of Health (U.S.) (Grant HG007005
Novel facultative Methylocella strains are active methane consumers at terrestrial natural gas seeps
- Author
- A Crombie
- A Ho
- A Kallistova
- A Klindworth
- A Pol
- A Putkinen
- A Schimmelmann
- A Smirnova
- A Vorobev
- AA DiSpirito
- AM Eren
- AT Crombie
- AT Crombie
- B Han
- B Langmead
- B Vekeman
- BL Dubbels
- BL Dubbels
- Bram Vekeman
- C Baciu
- C Baciu
- C Knief
- C Lyell
- CM Reddy
- DH Parks
- DN Miller
- EL Johnson
- F Chu
- F Chu
- F Reith
- F Tassi
- G Etiope
- G Etiope
- G Etiope
- G Etiope
- HN Vu
- I Tamas
- J Fiebig
- J Hall
- J Macauley
- Jan T. Keltjens
- JD Semrau
- JD Semrau
- JL Shennan
- JO Sharp
- KA Capone
- KF Kroeger
- KM Meyer
- KMW Anthony
- KS Swanson
- L Chistoserdova
- L Chistoserdova
- L Chistoserdova
- L Chistoserdova
- M Cappelletti
- M Ghashghavi
- M Rubin-Blum
- M Saunois
- Marina G. Kalyuzhnaya
- MC Redmond
- MC Redmond
- MG Dumont
- MK Sluis
- MO Ross
- MT Rahman
- Muhammad Farhan Ul Haque
- Muhammad Farhan Ul Haque
- N Hamamura
- N Picone
- NV Coleman
- NV Coleman
- P Mardina
- P. F. Dunfield
- PF Dunfield
- PJ Bottomley
- PL Tavormina
- PL Tavormina
- Q Wang
- R Kietavainen
- RB Jackson
- RC Dalal
- RC Edgar
- RS Oremland
- RW Howarth
- S Jensen
- S Kawagucci
- S Kolb
- S Liebner
- S Radajewski
- S Venturi
- SA Morris
- SB Dalsøren
- SE Belova
- SE Belova
- SE Dowd
- SE Dowd
- SG Osborn
- SN Dedysh
- SN Dedysh
- SN Dedysh
- SN Dedysh
- SN Dedysh
- SN Dedysh
- T Kotani
- T Nakagawa
- W Ashraf
- WS Reeburgh
- Y Chen
- Y Chen
- Y He
- Y-J Shiau
- Yoshihisa Hibi
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 04/10/2019
- Field of study
Natural gas seeps contribute to global climate change by releasing substantial amounts of the potent greenhouse gas methane and other climate-active gases including ethane and propane to the atmosphere. However, methanotrophs, bacteria capable of utilising methane as the sole source of carbon and energy, play a significant role in reducing the emissions of methane from many environments. Methylocella-like facultative methanotrophs are a unique group of bacteria that grow on other components of natural gas (i.e. ethane and propane) in addition to methane but a little is known about the distribution and activity of Methylocella in the environment. The purposes of this study were to identify bacteria involved in cycling methane emitted from natural gas seeps and, most importantly, to investigate if Methylocella-like facultative methanotrophs were active utilisers of natural gas at seep sites
Adolescent transport and unintentional injuries: a systematic analysis using the Global Burden of Disease Study 2019
- Author
- Abadi Kidanemariam Berhe
- Abbas Mosapour
- Abdallah M Samy
- Abdelrahman I Abushouk
- Abdiwahab Hashi
- Abdollah Mohammadian-Hafshejani
- Abdullah A Mamun
- Abdullah T Khoja
- Abhay Motiramji Gaidhane
- Abiy H Sinke
- Adam E Berman
- Adnan Kisa
- Adrian Otoiu
- Adrian Pana
- Afshin Maleki
- Agus Sudaryanto
- Ahamarshan Jayaraman Nagarajan
- Ahmad Ghashghaee
- Ahmad Zarei
- Ahmed I Hasaballah
- Ahmed Omar Bali
- Ai Koyanagi
- Ai-Min Wu
- Aidin Abedi
- Aisha Elsharkawy
- Akram Pourshams
- Akshaya Srikanth Bhagavathula
- Alberto Ortiz
- Alberto Raggi
- Alexander C Tsai
- Ali A Asadi-Pooya
- Ali Bijani
- Ali H Mokdad
- Ali Kabir
- Ali Koolivand
- Alireza Didarloo
- Amanda J Mason-Jones
- Amin Mousavi Khaneghah
- Amin Soheili
- Amir Abdoli
- Amir Almasi-Hashiani
- Amir Jalali
- Amir Radfar
- Amir Taherkhani
- Amira A Shaheen
- Amirhossein Sahebkar
- Amr Hassan
- Amy E Peden
- Anamika Pandey
- Anders O Larsson
- Andre Faro
- Andre M N Renzaho
- Andre Rodrigues Duraes
- Andreea Mirica
- Andrew T Olagunju
- André Karch
- Animut Tagele Tamiru
- Antonio Biondi
- Anurag Agrawal
- Anwar E Ahmed
- Arash Sarveazad
- Archith Boloor
- Arianna Maever L Amit
- Arielle Wilder Bell
- Aristidis Tsatsakis
- Artem Alekseevich Fomenkov
- Arvin Haj-Mirzaian
- Arya Aminorroaya
- Arya Haj-Mirzaian
- Asif Hanif
- Aso Mohammad Darwesh
- Assefa Ayalew Gebreslassie
- Assefa Desalew
- Ata Rafiee
- Atte Meretoja
- Ayesha Humayun
- Azeem Majeed
- Aziz Sheikh
- Azmeraw T Amare
- B Suresh Kumar Shetty
- Babak Eshrati
- Babak Moazen
- Bach Xuan Tran
- Bartosz Miazgowski
- Basema Saddik
- Beatriz Paulina Ayala Quintanilla
- Ben Lacey
- Bernhard T Baune
- Bhaskaran Unnikrishnan
- Biagio Simonetti
- Bing-Fang Hwang
- Bingyu Li
- Biresaw Wassihun Alemu
- Blessing Akombi-Inyang
- Bolajoko Olubukunola Olusanya
- Borhan Mansouri
- Boris Bikbov
- Brian J Hall
- Brigid Unim
- Budi Aji
- Carl Abelardo T Antonio
- Carlo Irwin Able Panelo
- Carlo La Vecchia
- Carlos A Castañeda-Orjuela
- Catalina Liliana Andrei
- Chandrashekhar T Sreeramareddy
- Chenkai Wu
- Chhabi Lal Ranabhat
- Chirag P Doshi
- Christian Kieling
- Christoph Nowak
- Christopher J L Murray
- Chuanhua Yu
- Chukwudi A Nnaji
- Claudio Alberto Dávila-Cervantes
- Claudiu Herteliu
- Cong Zhu
- Corina Benjet
- Dan J Stein
- Daniel Diaz
- Dara K Mohammad
- David C Schwebel
- David Edvardsson
- David Laith Rawaf
- Davide Sattin
- Davood Anvari
- Davoud Adham
- Deanna Anderlini
- Deborah Carvalho Malta
- Deepak Saxena
- Dejana Braithwaite
- Demelash Woldeyohannes Handiso
- Deniz Yuce
- Devasahayam J Christopher
- Dharmesh Kumar Lal
- Dian Kusuma
- Diana Dias da Silva
- Dickson A Amugsi
- Diego Augusto Santos Silva
- Diego De Leo
- Diep Ngoc Nguyen
- Dina Nur Anggraini Ningrum
- Dinh-Toi Chu
- Eduarda Fernandes
- Ehsan Sadeghi
- Elena V Gnedovskaya
- Elisabetta Pupillo
- Elvis Korku Avenyo
- Eman Abu-Gharbieh
- Emma U R Smith
- Emmanuel K Peprah
- Endalkachew Worku Mengesha
- Enrico Rubagotti
- Ensiyeh Jenabi
- Era Upadhyay
- Erkin M Mirrakhimov
- Ester Cerin
- Ettore Beghi
- Eugene Sobngwi
- Eun-Kee Park
- Fahad Mashhour Alanezi
- Faheem Hyder Pottoo
- Fakher Rahim
- Falk Schwendicke
- Farahnaz Joukar
- Fares Alahdab
- Farhad Ghamari
- Fariba Dorostkar
- Farshad Farzadfar
- Fatemeh Heydarpour
- Felix Akpojene Ogbo
- Felix Carvalho
- Feng Sha
- Fereshteh Ansari
- Fereshteh Mehri
- Fernando Pio De la Hoz
- Ferrán Catalá-López
- Firooz Esmaeilzadeh
- Flavia M Cicuttini
- Florentino Luciano Caetano Dos Santos
- Florian Fischer
- Foad Abd-Allah
- Francesco S Violante
- Francisco Rogerlândio Martins-Melo
- G Anil Kumar
- G K Mini
- Gabriel Martinez
- Gabrielle B Britton
- Gbenga A Kayode
- Gebreamlak Gebremedhn Gebremeskel
- George C Patton
- Georges Nguefack-Tsague
- Getinet Ayano
- Ghobad Moradi
- Gianfranco Alicandro
- Giang Thu Vu
- Giovanni Damiani
- Giulia Carreras
- Giulio Castelpietra
- Giuseppe Gorini
- Godfrey M Rwegerera
- Govinda Prasad Dhungana
- Graeme J Hankey
- Gregory A Roth
- Habibolah Khazaie
- Hadi Hassankhani
- Hadi Pourjafar
- Hadi Zarafshan
- Hai Quang Pham
- Haijiang Dai
- Hailay Abrha Gesesew
- Hamed Mirzaei
- Hamideh Salimzadeh
- Hamidreza Haririan
- Harish Chander Gugnani
- Hassan Abolhassani
- Helen Slater
- Henok Biresaw Netsere
- Hermann Brenner
- Hesham M Al-Mekhlafi
- Hiroyasu Iso
- Hsing-Yi Chang
- Hung Chak Ho
- Huong Lan Thi Nguyen
- Iman Ansari
- In-Hwan Oh
- Inga Dora Sigfusdottir
- Ionut Negoi
- Irena M Ilic
- Ireneous N Soyiri
- Irina Filip
- Irmina Maria Michalek
- Isabela M Bensenor
- Islam Y Elgendy
- Ismael R Campos-Nonato
- Ivo Iavicoli
- Iván Landires
- Iyad Sultan
- Jacek Jerzy Jozwiak
- Jacob Olusegun Olusanya
- Jacqueline Elizabeth Alcalde-Rabanal
- Jae Il Shin
- Jagadish Rao Padubidri
- Jalal Arabloo
- James L Fisher
- James Leigh
- Janni Leung
- Jasvinder A Singh
- Javad Nazari
- Jaykaran Charan
- Jean Jacques Noubiap
- Jee-Young Jasmine Choi
- Jeevan Pereira
- Jennifer Rickard
- Jing Nie
- Joao Mauricio Castaldelli-Maia
- Johan Ärnlöv
- John J McGrath
- John S Ji
- John S Santelli
- Joht Singh Chandan
- Jordi Alonso
- Jose Martinez-Raga
- Josep Maria Haro
- Joseph L Ward
- Jost B Jonas
- João Pedro Silva
- Juan J Carrero
- Juan Sanabria
- Juanita A Haagsma
- Julio Cesar Campuzano Rincon
- Jung-Chen Chang
- Kairat Davletov
- Kanaan Hamagharib Abdullah
- Kate Louise Francis
- Kavumpurathu Raman Thankappan
- Kazumasa Yamagishi
- Keivan Ahmadi
- Kelly M Jones
- Kerem Shuval
- Kerrie E Doyle
- Keshab Deuba
- Ketema Bizuwork Gebremedhin
- Kewal Krishan
- Keyghobad Ghadiri
- Keyvan Pakshir
- Khaled Khatab
- Khalid A Altirkawi
- Khashayar Afshari
- Khezar Hayat
- Khurshid Alam
- Kiana Ramezanzadeh
- Kidanemaryam Berhe
- Kiomars Sharafi
- Konrad Pesudovs
- Krittika Bhattacharyya
- Lal Rawal
- Lalit Dandona
- Leake Gebremeskel
- Lee-Ling Lim
- Leeberk Raja Inbaraj
- Leila Doshmangir
- Leila R Kalankesh
- Leonardo Roever
- Leticia Avila-Burgos
- Lorainne Tudor Car
- Lorenzo Monasta
- Luca Ronfani
- Lucas Guimarães Abreu
- Luis Alberto Cámera
- M Mofizul Islam
- Maarten J Postma
- Maciej Banach
- Maha El Tantawi
- Maha Moh'd Wahbi Atout
- Mahalaqua Nazli Khatib
- Mahaveer Golechha
- Mahesh P A
- Malke Asaad
- Man Mohan Mehndiratta
- Manasi Kumar
- Mansour Ghafourifard
- Manthan Dilipkumar Janodia
- Manu Raj Mathur
- Marcel Ausloos
- Marcello Tonelli
- Marco Vacante
- Marcos Roberto Tovani-Palone
- Mariya Vladimirovna Titova
- Mark A Stokes
- Marwa Rashad Salem
- Maryam Khayamzadeh
- Maryam Mirzaei
- Maryam Zamanian
- Maseer Khan
- Masood Ali Shaikh
- Masoud Foroutan
- Matilde Leonardi
- Mayowa O Owolabi
- Maziar Moradi-Lakeh
- Md Ismail Tareque
- Md Nuruzzaman Khan
- Meghdad Pirsaheb
- Mehdi Hosseinzadeh
- Mehdi Naderi
- Mehran Alijanzadeh
- Mehran Asadi-Aliabadi
- Michael A Piradov
- Michael K Hole
- Michael R M Abrigo
- Michael R Phillips
- Michael T Chung
- Michal Grivna
- Michelle L Bell
- Miguel A Barboza
- Mihaela Hostiuc
- Mihajlo Jakovljevic
- Mika Kivimäki
- Mika Shigematsu
- Mikhail Sergeevich Zastrozhin
- Mikk Jürisson
- Milena D Ilic
- Milena M Santric-Milicevic
- Ming-Chieh Li
- Miriam Levi
- Mohamed Hsairi
- Mohamed M Gad
- Mohammad Abdollahi
- Mohammad Ali Jahani
- Mohammad Ali Mansournia
- Mohammad Ali Sahraian
- Mohammad Ebrahimi Kalan
- Mohammad Hasan Rabiee
- Mohammad Hifz Ur Rahman
- Mohammad Hossein Bakhshaei
- Mohammad Khammarnia
- Mohammad Reza Sobhiyeh
- Mohammad Sadegh Rezai
- Mohammad Zamani
- MohammadBagher Shamsi
- Mohammed Ibrahim Mohialdeen Gubari
- Mohammed Shannawaz
- Mohiuddin Ahsanul Kabir Chowdhury
- Mohsen Bayati
- Mohsen Naghavi
- Mokhtar Mahdavi Mahdavi
- Mona M Khater
- Morenike Oluwatoyin Folayan
- Morteza Arab-Zozani
- Morteza Mahmoudi
- Morteza Oladnabi
- Moses K Muriithi
- Mostafa Dianatinasab
- Mostafa Hosseini
- Mowafa Househ
- Muhammad Aziz Rahman
- Mukhammad David Naimzada
- Muktar Omer Omer
- Muluken Bekele Sorrie
- Mustafa Z Younis
- Myron Anthony Godinho
- Naohiro Yonemoto
- Narayanaswamy Venketasubramanian
- Naser Kamyari
- Nataliya A Foigt
- Nauman Khalid
- Navid Rabiee
- Nazir Fattahi
- Neeraj Bedi
- Negar Rezaei
- Nelson Alvis-Guzman
- Nicholas J K Breitborde
- Nicholas J Kassebaum
- Nicola Luigi Bragazzi
- Nihad A Almasri
- Nihal Thomas
- Nikha Bhardwaj
- Nikita Otstavnov
- Nikolaos Dervenis
- Nima Hafezi-Nejad
- Nima Rezaei
- Nirun Intarut
- Nithin Kumar
- Nizal Sarrafzadegan
- Noushin Mohammadifard
- Nuwan Darshana Wickramasinghe
- Nuworza Kugbey
- Obinna E Onwujekwe
- Oladimeji M Adebayo
- Olayinka Stephen Ilesanmi
- Oluwaseyi Dolapo Somefun
- Om P Kurmi
- Omid Shafaat
- Onome Bright Oghenetega
- Palash Chandra Banik
- Pallab K Maulik
- Pankaj Bhardwaj
- Panniyammakal Jeemon
- Paolo Lauriola
- Parnaz Daneshpajouhnejad
- Pascual R Valdez
- Paul H Lee
- Paul J Villeneuve
- Paul Yip
- Paula Moraga
- Paulo A Lotufo
- Peilin Shi
- Perminder S Sachdev
- Peter Njenga Keiyoro
- Peter S Azzopardi
- Peter T N Memiah
- Petur B Juliusson
- Phetole Walter Mahasha
- Philimon N Gona
- Pietro Ferrara
- Prateek Rastogi
- Praveen Hoogar
- Priya Rathi
- Qing Lan
- Raaj Kishore Biswas
- Rabia Hussain
- Rafael Alves Guimarães
- Rafael Tabarés-Seisdedos
- Raffaele Palladino
- Rahman Shiri
- Rahmatollah Moradzadeh
- Raimundas Lunevicius
- Rajaa M Al-Raddadi
- Rajeev Gupta
- Rajesh Sagar
- Rakhi Dandona
- Ralph Maddison
- Ramesh Holla
- Randah R Hamadeh
- Rannveig Sigurvinsdottir
- Ratilal Lalloo
- Ravensara S Travillian
- Ravi Prakash Jha
- Rawlance Ndejjo
- Razique Anwer
- Rebecca Q Ivers
- Rekha Thapar
- Reza Heidari-Soureshjani
- Reza Malekzadeh
- Reza Mohammadpourhodki
- Reza Rawassizadeh
- Riaz Uddin
- Richard A Burns
- Richard G Wamai
- Ritesh G Menezes
- Robert Ancuceanu
- Robert Kaba Alhassan
- Rohan Borschmann
- Rohollah Kalhor
- Ronny Westerman
- Rosario Cárdenas
- Rupak Desai
- Russell M Viner
- Ruth W Kimokoti
- Ruxandra Irina Negoi
- S Mohammad Sajadi
- Saad M A Dahlawi
- Sadaf Esteghamati
- Sadaf G Sepanlou
- Saeed Amini
- Saeed Shahabi
- Saeed Shakiba
- Sahar Saeedi Moghaddam
- Sahel Valadan Tahbaz
- Salah Eddin Karimi
- Salman Rawaf
- Samad Azari
- Saman Esmaeilnejad
- Samar Al-Hajj
- Samath Dhamminda Dharmaratne
- Sameer Vali Gopalani
- Samer Hamidi
- Sanam Ebtehaj
- Sanjay Basu
- Sanni Yaya
- Santosh Kumar Tadakamadla
- Santosh Varughese
- Saqib Ali
- Sara Sheikhbahaei
- Saravanan Muthupandian
- Sarika Chaturvedi
- Savita Lasrado
- Scott B Patten
- Segun Emmanuel Ibitoye
- Seok-Jun Yoon
- Sergio I Prada
- Seth Christopher Yaw Appiah
- Seyed Hossein Yahyazadeh Jabbari
- Seyed Mohammad Riahi
- Seyed Sina Naghibi Irvani
- Seyed-Mohammad Fereshtehnejad
- Seyedeh Zahra Masoumi
- Sezer Kisa
- Shadieh Mohammadi
- Shafiu Mohammed
- Shailesh M Advani
- Shaimaa I El-Jaafary
- Shane Douglas Morrison
- Shankar M Bakkannavar
- Shanshan Li
- Sharareh Eskandarieh
- Sharath Burugina Nagaraja
- Shaun Wen Huey Lee
- Sheikh Mohammed Shariful Islam
- Sheng-Chia Chung
- Shirin Djalalinia
- Shuhei Nomura
- Siamak Sabour
- Silvano Gallus
- Silvia Schiavolin
- Simon I Hay
- Simon Øverland
- Sivan Yegnanarayana Iyer Saraswathy
- Soewarta Kosen
- Sofia Androudi
- Soheil Hassanipour
- Sojib Bin Zaman
- Somayeh Bohlouli
- Songhomitra Panda-Jonas
- Sonia Lewycka
- Sonia Saxena
- Soraya Siabani
- Sorin Hostiuc
- Soufiane Boufous
- Sowmya J Rao
- Srinivas Goli
- Srinivasa Rao Bolla
- Stanislav S Otstavnov
- Stefan Lorkowski
- Stephen S Lim
- Subramanian Senthilkumaran
- Supreet Kaur
- Suraj Bhattarai
- Susan Fred Rumisha
- Susan M Sawyer
- Suzanne Lyn Barker-Collo
- Syed Amir Gilani
- Syed Mohamed Aljunid
- Syed Saoud Zaidi
- Tahereh Javaheri
- Takahiro Tabuchi
- Takeshi Fukumoto
- Tanuj Kanchan
- Tanvir M Huda
- Taraneh Yousefinezhadi
- Tariku Tesfaye Bekuma
- Tauseef Ahmad
- Ted R Miller
- Teklehaimanot Gereziher Haile
- Tesega Tesega Mengistu Birhanu
- Teshome Gebre
- Theo Vos
- Thirunavukkarasu Sathish
- Till Winfried Bärnighausen
- Tomas Y Ferede
- Tomasz Miazgowski
- Tomislav Mestrovic
- Tommi Juhani Vasankari
- Traian Vasile Constantin
- Tuomo J Meretoja
- Turki M Alanzi
- Ulrich Otto Mueller
- Usman Iqbal
- Vafa Rahimi-Movaghar
- Vahid Rashedi
- Vahid Yazdi-Feyzabadi
- Valentin Yurievich Skryabin
- Valery L Feigin
- Van Charles Lansingh
- Vasily Vlassov
- Vegard Skirbekk
- Veincent Christian Filipino Pepito
- Vera Marisa Costa
- Victor Adekanmbi
- Vijay Kumar Chattu
- Vinay Nangia
- Vinod C Nayak
- Virendra Singh
- Virginia Nuñez-Samudio
- Vivekanand Jha
- Walter Mendoza
- Xiaochen Dai
- Xiu-Ju George Zhao
- Xuefeng Liu
- Yafeng Wang
- Yanzhong Wang
- Yared Asmare Aynalem
- Yasir Waheed
- Yong Yu
- Yordanos Gizachew Yeshitila
- Young-Eun Kim
- Yuan-Pang Wang
- Yuichiro Yano
- Yuming Guo
- Yun Jin Kim
- Yunquan Zhang
- Zahid A Butt
- Zahiruddin Quazi Syed
- Zelalem Nigussie Azene
- Zhi-Jiang Zhang
- Ziyad Al-Aly
- Zohra S Lassi
- Zubair Kabir
- Zulfiqar A Bhutta
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2022
- Field of study
Background: Globally, transport and unintentional injuries persist as leading preventable causes of mortality and morbidity for adolescents. We sought to report comprehensive trends in injury-related mortality and morbidity for adolescents aged 10–24 years during the past three decades. Methods: Using the Global Burden of Disease, Injuries, and Risk Factors 2019 Study, we analysed mortality and disability-adjusted life-years (DALYs) attributed to transport and unintentional injuries for adolescents in 204 countries. Burden is reported in absolute numbers and age-standardised rates per 100 000 population by sex, age group (10–14, 15–19, and 20–24 years), and sociodemographic index (SDI) with 95% uncertainty intervals (UIs). We report percentage changes in deaths and DALYs between 1990 and 2019. Findings: In 2019, 369 061 deaths (of which 214 337 [58%] were transport related) and 31·1 million DALYs (of which 16·2 million [52%] were transport related) among adolescents aged 10–24 years were caused by transport and unintentional injuries combined. If compared with other causes, transport and unintentional injuries combined accounted for 25% of deaths and 14% of DALYs in 2019, and showed little improvement from 1990 when such injuries accounted for 26% of adolescent deaths and 17% of adolescent DALYs. Throughout adolescence, transport and unintentional injury fatality rates increased by age group. The unintentional injury burden was higher among males than females for all injury types, except for injuries related to fire, heat, and hot substances, or to adverse effects of medical treatment. From 1990 to 2019, global mortality rates declined by 34·4% (from 17·5 to 11·5 per 100 000) for transport injuries, and by 47·7% (from 15·9 to 8·3 per 100 000) for unintentional injuries. However, in low-SDI nations the absolute number of deaths increased (by 80·5% to 42 774 for transport injuries and by 39·4% to 31 961 for unintentional injuries). In the high-SDI quintile in 2010–19, the rate per 100 000 of transport injury DALYs was reduced by 16·7%, from 838 in 2010 to 699 in 2019. This was a substantially slower pace of reduction compared with the 48·5% reduction between 1990 and 2010, from 1626 per 100 000 in 1990 to 838 per 100 000 in 2010. Between 2010 and 2019, the rate of unintentional injury DALYs per 100 000 also remained largely unchanged in high-SDI countries (555 in 2010 vs 554 in 2019; 0·2% reduction). The number and rate of adolescent deaths and DALYs owing to environmental heat and cold exposure increased for the high-SDI quintile during 2010–19. Interpretation: As other causes of mortality are addressed, inadequate progress in reducing transport and unintentional injury mortality as a proportion of adolescent deaths becomes apparent. The relative shift in the burden of injury from high-SDI countries to low and low–middle-SDI countries necessitates focused action, including global donor, government, and industry investment in injury prevention. The persisting burden of DALYs related to transport and unintentional injuries indicates a need to prioritise innovative measures for the primary prevention of adolescent injury. Funding: Bill & Melinda Gates Foundation
Search for Nearly Mass-Degenerate Higgsinos Using Low-Momentum Mildly Displaced Tracks in pp Collisions at sqrt(s)=13 TeV with the ATLAS Detector
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- Zhang X.
- Zhang X.
- Zhang Y.
- Zhang Y.
- Zhang Y.
- Zhang Z.
- Zhang Z.
- Zhao H.
- Zhao T.
- Zhao Y.
- Zhao Z.
- Zhao Z.
- Zhemchugov A.
- Zheng J.
- Zheng K.
- Zheng X.
- Zheng Z.
- Zhong D.
- Zhou B.
- Zhou H.
- Zhou N.
- Zhou Y.
- Zhou Y.
- Zhu C. G.
- Zhu J.
- Zhu Y.
- Zhu Y.
- Zhuang X.
- Zhukov K.
- Zimine N. I.
- Zinsser J.
- Ziolkowski M.
- Zoccoli A.
- Zoch K.
- Zorbas T. G.
- Zormpa O.
- Zou W.
- Zwalinski L.
- Ženiš T.
- Živković L.
- Publication venue
- American Physical Society
- Publication date
- 01/01/2024
- Field of study
Alignment of the ATLAS Inner Detector in Run 2
- Author
- Aad G.
- Abbott B.
- Abbott D. C.
- Abeling K.
- Abhayasinghe D. K.
- Abidi S. H.
- AbouZeid O. S.
- Abraham N. L.
- Abramowicz H.
- Abreu H.
- Abud A. Abed
- Abulaiti Y.
- Acharya B. S.
- Achkar B.
- Adam L.
- Adamczyk L.
- Adamek L.
- Adelman J.
- Adersberger M.
- Adiguzel A.
- Adorni S.
- Adye T.
- Affolder A. A.
- Afik Y.
- Agapopoulou C.
- Agaras M. N.
- Aggarwal A.
- Agheorghiesei C.
- Aguilar-Saavedra J. A.
- Ahmad A.
- Ahmadov F.
- Ahmed W. S.
- Ai X.
- Aielli G.
- Akatsuka S.
- Akbiyik M.
- Akesson T. P. A.
- Akilli E.
- Akimov A.
- Al Khoury K.
- Alberghi G. L.
- Albert J.
- Alderweireldt S.
- Aleksa M.
- Aleksandrov I. N.
- Alexa C.
- Alexopoulos T.
- Alfonsi A.
- Alfonsi F.
- Alhroob M.
- Ali B.
- Ali S.
- Aliev M.
- Alimonti G.
- Allaire C.
- Allbrooke B. M. M.
- Allen B. W.
- Allport P. P.
- Aloisio A.
- Alonso F.
- Alpigiani C.
- Alves F. L. Lucio
- Alviggi M. G.
- Ambler A.
- Ambroz L.
- Amelung C.
- Amidei D.
- Amoroso S.
- Amrouche C. S.
- An F.
- Anastopoulos C.
- Andari N.
- Andeen T.
- Anders J. K.
- Andrean S. Y.
- Andreazza A.
- Andrei V
- Anelli C. R.
- Angelidakis S.
- Angerami A.
- Anisenkov A.
- Annovi A.
- Antel C.
- Anthony M. T.
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- Zivkovic L.
- Zobernig G.
- Zoccoli A.
- Zoch K.
- Zorbas T. G.
- Zou R.
- Zwalinski L.
- Publication venue
- place:NEW YORK
- Publication date
- 01/01/2009
- Field of study
The performance of the ATLAS Inner Detector alignment has been studied using pp collision data at v s = 13 TeV collected by the ATLAS experiment during Run 2 (2015-2018) of the Large Hadron Collider (LHC). The goal of the detector alignment is to determine the detector geometry as accurately as possible and correct for time-dependent movements. The Inner Detector alignment is based on the minimization of track-hit residuals in a sequence of hierarchical levels, from global mechanical assembly structures to local sensors. Subsequent levels have increasing numbers of degrees of freedom; in total there are almost 750,000. The alignment determines detector geometry on both short and long timescales, where short timescales describe movementswithin anLHCfill. The performance and possible track parameter biases originating from systematic detector deformations are evaluated. Momentum biases are studied using resonances decaying to muons or to electrons. The residual sagitta bias and momentum scale bias after alignment are reduced to less than similar to 0.1 TeV-1 and 0.9 x 10(-3), respectively. Impact parameter biases are also evaluated using tracks within jets
Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019
- Author
- Abbafati Cristiana
- Abbas Kaja M.
- Abbasi Mohammad
- Abbasi-Kangevari Mohsen
- Abbasifard Mitra
- Abbastabar Hedayat
- Abd El Razek Hassan Magdy
- Abd El Razek Muhammed Magdy
- Abd-Allah Foad
- Abdelalim Ahmed
- Abdollahi Mohammad
- Abdollahpour Ibrahim
- Abdulkader Rizwan Suliankatchi
- Abdullah Kanaan Hamagharib
- Abedi Aidin
- Abedi Parisa
- Abegaz Kedir Hussein
- Abolhassani Hassan
- Abosetugn Akine Eshete
- Aboyans Victor
- Abrams Elissa M.
- Abreu Lucas Guimaraes
- Abrigo Michael R. M.
- Abu Haimed Abdulaziz Khalid
- Abu-Gharbieh Eman
- Abu-Raddad Laith Jamal
- Abualhasan Ahmed
- Abushouk Abdelrahman I.
- Acebedo Alyssa
- Ackerman Ilana N.
- Adabi Maryam
- Adair Tim
- Adamu Abdu A.
- Adebayo Oladimeji M.
- Adedeji Isaac Akinkunmi
- Adekanmbi Victor
- Adelson Jaimie D.
- Adeoye Abiodun Moshood
- Adetokunboh Olatunji O.
- Adham Davoud
- Advani Shailesh M.
- Afarideh Mohsen
- Afshari Mahdi
- Afshin Ashkan
- Agardh Emilie E.
- Agarwal Gina
- Agasthi Pradyumna
- Agesa Kareha M.
- Aghaali Mohammad
- Aghamir Seyed Mohammad Kazem
- Agrawal Anurag
- Ahmad Tauseef
- Ahmadi Alireza
- Ahmadi Keivan
- Ahmadi Mehdi
- Ahmadieh Hamid
- Ahmadpour Ehsan
- Ahmed Muktar Beshir
- Aji Budi
- Akalu Temesgen Yihunie
- Akinyemi Rufus Olusola
- Akinyemiju Tomi
- Akombi Blessing
- Akunna Chisom Joyqueenet
- Al-Aly Ziyad
- Al-Mekhlafi Hesham M.
- Al-Raddadi Rajaa M.
- Alahdab Fares
- Alam Khurshid
- Alam Noore
- Alam Samiah
- Alam Tahiya
- Alanezi Fahad Mashhour
- Alanzi Turki M.
- Albertson Samuel B.
- Alcalde-Rabanal Jacqueline Elizabeth
- Alema Niguse Meles
- Alemu Biresaw Wassihun
- Alemu Yihun Mulugeta
- Alhabib Khalid F.
- Alhassan Robert Kaba
- Ali Muhammad
- Ali Saqib
- Alicandro Gianfranco
- Alijanzadeh Mehran
- Alinia Cyrus
- Alipour Vahid
- Alizade Hesam
- Aljunid Syed Mohamed
- Alla Francois
- Allebeck Peter
- Almadi Majid Abdulrahman Hamad
- Almasi Ali
- Almasi-Hashiani Amir
- Almasri Nihad A.
- Almulhim Abdulaziz M.
- Alonso Jordi
- Altirkawi Khalid A.
- Alumran Arwa Khalid
- Alvis-Guzman Nelson
- Alvis-Zakzuk Nelson J.
- Amare Azmeraw T.
- Amare Bekalu
- Amini Saeed
- Amini-Rarani Mostafa
- Aminorroaya Arya
- Amiri Fatemeh
- Amit Arianna Maever L.
- Amugsi Dickson A.
- Amul Gianna Gayle Herrera
- Anbesu Etsay Woldu
- Ancuceanu Robert
- Anderlini Deanna
- Anderson Jason A.
- Andrei Catalina Liliana
- Andrei Tudorel
- Androudi Sofia
- Angus Colin
- Anjomshoa Mina
- Ansari Fereshteh
- Ansari Iman
- Ansari-Moghaddam Alireza
- Antonazzo Ippazio Cosimo
- Antonio Carl Abelardo T.
- Antony Catherine M.
- Antriyandarti Ernoiz
- Anvari Davood
- Anwer Razique
- Appiah Seth Christopher Yaw
- Arab-Zozani Morteza
- Arabloo Jalal
- Aravkin Aleksandr Y.
- Arba Aseb Arba Kinfe
- Aremu Olatunde
- Ariani Filippo
- Aripov Timur
- Armoon Bahram
- Arnlov Johan
- Arowosegbe Oluwaseyi Olalekan
- Aryal Krishna K.
- Arzani Afsaneh
- Asaad Malke
- Asadi-Aliabadi Mehran
- Asadi-Pooya Ali A.
- Asgari Samaneh
- Asghari Babak
- Ashbaugh Charlie
- Assmus Michael
- Atafar Zahra
- Athari Seyyed Shamsadin
- Atnafu Desta Debalkie
- Atout Maha Moh'd Wahbi
- Atre Sachin R.
- Atteraya Madhu Sudhan
- Ausloos Floriane
- Ausloos Marcel
- Avila-Burgos Leticia
- Avokpaho Euripide Frinel Gbenato Arthur
- Ayano Getinet
- Ayanore Martin Amogre
- Aynalem Getie Lake
- Aynalem Yared Asmare
- Ayza Muluken Altaye
- Azari Samad
- Azarian Ghasem
- Azene Zelalem Nigussie
- Azhar Gulrez
- Azzopardi Peter S.
- Babaee Ebrahim
- Badawi Alaa
- Badiye Ashish D.
- Bagherzadeh Mojtaba
- Bagli Eleni
- Bahrami Mohammad Amin
- Baig Atif Amin
- Bairwa Mohan
- Bakhshaei Mohammad Hossein
- Bakhtiari Ahad
- Bakkannavar Shankar M.
- Balachandran Arun
- Balakrishnan Senthilkumar
- Balalla Shivanthi
- Balassyano Shelly
- Baldasseroni Alberto
- Bali Ahmed Omar
- Ball Kylie
- Ballew Shoshana H.
- Balzi Daniela
- Banach Maciej
- Bandpei Mohammad A. Mohseni
- Banerjee Srikanta K.
- Banik Palash Chandra
- Bannick Marlena S.
- Bante Agegnehu Bante
- Bante Simachew Animen
- Baraki Adhanom Gebreegziabher
- Barboza Miguel A.
- Barker-Collo Suzanne Lyn
- Barnighausen Till Winfried
- Barrero Lope H.
- Barthelemy Celine M.
- Barua Lingkan
- Barzegar Akbar
- Basaleem Huda
- Bassat Quique
- Basu Sanjay
- Baune Bernhard T.
- Bayati Mohsen
- Baye Bayisa Abdissa
- Bazmandegan Gholamreza
- Becker Jacob S.
- Bedi Neeraj
- Beghi Ettore
- Behzadifar Masoud
- Bejot Yannick
- Bekuma Tariku Tesfaye Tesfaye
- Bell Michelle L.
- Bello Aminu K.
- Bender Rose G.
- Bennett Derrick A.
- Bennitt Fiona B.
- Bensenor Isabela M.
- Benziger Catherine P.
- Berhe Kidanemaryam
- Berman Adam E.
- Bernabe Eduardo
- Bernstein Robert S.
- Bertolacci Gregory J.
- Bhagavathula Akshaya Srikanth
- Bhageerathy Reshmi
- Bhala Neeraj
- Bhandari Dinesh
- Bhardwaj Pankaj
- Bhat Anusha Ganapati
- Bhattacharyya Krittika
- Bhattarai Suraj
- Bhutta Zulfiqar A.
- Bibi Sadia
- Bicer Burcu Kucuk
- Biehl Molly H.
- Bijani Ali
- Bikbov Boris
- Bilano Ver
- Bin Sayeed Muhammad Shahdaat
- Bin Zaman Sojib
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- Bisanzio Donal
- Bisignano Catherine
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- Bitew Helen
- Bjorge Tone
- Bockarie Moses John
- Bohlouli Somayeh
- Bohluli Mehdi
- Bojia Hunduma Amensisa
- Bolla Srinivasa Rao
- Boloor Archith
- Boon-Dooley Alexandra S.
- Borges Guilherme
- Borzi Antonio Maria
- Borzouei Shiva
- Bose Dipan
- Bosetti Cristina
- Boston Sofia
- Boufous Soufiane
- Bourne Rupert
- Brady Oliver J.
- Braithwaite Dejana
- Brauer Michael
- Brayne Carol
- Breitborde Nicholas J. K.
- Breitner Susanne
- Brenner Hermann
- Breusov Alexey V.
- Briant Paul Svitil
- Briggs Andrew M.
- Briko Andrey Nikolaevich
- Briko Nikolay Ivanovich
- Britton Gabrielle B.
- Brugha Traolach
- Bryazka Dana
- Buchbinder Rachelle
- Bumgarner Blair R.
- Burkart Katrin
- Burnett Richard Thomas
- Busse Reinhard
- Butt Zahid A.
- Caetano dos Santos Florentino Luciano
- Cahill Leah E.
- Cahuana-Hurtado Lucero
- Cai Tianji
- Callender Charlton S. K. H.
- Camera Luis Alberto
- Campos-Nonato Ismael R.
- Cao Jackie
- Car Josip
- Car Lorainne Tudor
- Cardenas Rosario
- Carreras Giulia
- Carrero Juan J.
- Carvalho Felix
- Castaldelli-Maia Joao Mauricio
- Castaneda-Orjuela Carlos A.
- Castelpietra Giulio
- Castle Chris D.
- Castro Emma
- Castro Franz
- Catala-Lopez Ferran
- Causey Kate
- Cederroth Christopher R.
- Cercy Kelly M.
- Cerin Ester
- Chalek Julian
- Chandan Joht Singh
- Chang Alex R.
- Chang Angela Y.
- Chang Jung-Chen
- Chang Kai-Lan
- Charan Jaykaran
- Charlson Fiona J.
- Chattu Vijay Kumar
- Chaturvedi Sarika
- Cherbuin Nicolas
- Chimed-Ochir Odgerel
- Chin Ken Lee
- Chirinos-Caceres Jesus Lorenzo
- Cho Daniel Youngwhan
- Choi Jee-Young Jasmine
- Christensen Hanne
- Chu Dinh-Toi
- Chung Michael T.
- Chung Sheng-Chia
- Cicuttini Flavia M.
- Ciobanu Liliana G.
- Cirillo Massimo
- Cislaghi Beniamino
- Classen Thomas Khaled Dwayne
- Cohen Aaron J.
- Collins Emma L.
- Comfort Haley
- Compton Kelly
- Conti Sara
- Cooper Owen R.
- Corso Barbara
- Cortesi Paolo Angelo
- Costa Vera Marisa
- Cousin Ewerton
- Cowden Richard G.
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- Cromwell Elizabeth A.
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- Cross Di H.
- Cross Marita
- Crowe Christopher Stephen
- Cruz Jessica A.
- Cummins Steven
- Cunningham Matthew
- D'Amico Emanuele
- da Silva Diana Dias
- Dahlawi Saad M. A.
- Dai Haijiang
- Dai Hancheng
- Damasceno Albertino Antonio Moura
- Damiani Giovanni
- Dandona Lalit
- Dandona Rakhi
- Daneshpajouhnejad Parnaz
- Dangel William James
- Danielsson Anna-Karin
- Dargan Paul I.
- Darshan B. B.
- Darwesh Aso Mohammad
- Daryani Ahmad
- Das Gupta Rajat
- Das Neves Jose
- Das Jai K.
- Dash Aditya Prasad
- Davey Gail
- Davila-Cervantes Claudio Alberto
- Davis Adrian C.
- Davitoiu Dragos Virgil
- Davletov Kairat
- De Leo Diego
- De Neve Jan-Walter
- Dean Frances E.
- DeCleene Nicole K.
- Deen Amanda
- Defo Barthelemy Kuate
- Degenhardt Louisa
- DeLang Marissa
- Dellavalle Robert Paul
- Demeke Feleke Mekonnen
- Demoz Gebre Teklemariam
- Demsie Desalegn Getnet
- Denova-Gutierrez Edgar
- Dereje Nebiyu Dereje
- Deribe Kebede
- Dervenis Nikolaos
- Desai Rupak
- Desalew Assefa
- Dessie Getenet Ayalew
- Deuba Keshab
- Dharmaratne Samath Dhamminda
- Dhungana Govinda Prasad
- Dianatinasab Mostafa
- Diaz Daniel
- Dichgans Martin
- Didarloo Alireza
- Dingels Zachary V.
- Dippenaar Ilse N.
- Dirac M. Ashworth
- Djalalinia Shirin
- Do Hoa Thi
- Dokova Klara
- Doku David Teye
- Dolecek Christiane
- Dolgert Andrew J.
- Dorostkar Fariba
- Doshi Chirag P.
- Doshi Pratik P.
- Doshmangir Leila
- Douiri Abdel
- Doxey Matthew C.
- Doyle Kerrie E.
- Driscoll Tim Robert
- Dubljanin Eleonora
- Dunachie Susanna J.
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- Duraes Andre Rodrigues
- Eagan Arielle Wilder
- Ebrahimi Hedyeh
- Edvardsson David
- Effiong Andem
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- El Nahas Nevine
- El Sayed Iman
- El Tantawi Maha
- El-Jaafary Shaimaa I.
- Elbarazi Iffat
- Elgendy Islam Y.
- Elhabashy Hala Rashad
- Elsharkawy Aisha
- Elyazar Iqbal R. F.
- Emamian Mohammad Hassan
- Emmons-Bell Sophia
- Erskine Holly E.
- Eshrati Babak
- Eskandari Khalil
- Eskandarieh Sharareh
- Esmaeilnejad Saman
- Esmaeilzadeh Firooz
- Esteghamati Alireza
- Esteghamati Sadaf
- Estep Kara
- Etemadi Arash
- Etisso Atkilt Esaiyas
- Ezekannagha Oluchi
- Fanzo Jessica
- Farag Tamer
- Farahmand Mohammad
- Faraj Anwar
- Faraon Emerito Jose A.
- Fareed Mohammad
- Faridnia Roghiyeh
- Farinha Carla Sofia e Sa
- Farioli Andrea
- Faris Pawan Sirwan
- Faro Andre
- Faruque Mithila
- Farzadfar Farshad
- Fattahi Nazir
- Fazaeli Ali Akbar
- Fazlzadeh Mehdi
- Feigin Valery L.
- Feldman Rachel
- Fereshtehnejad Seyed-Mohammad
- Fernandes Eduarda
- Ferrara Giannina
- Ferrara Pietro
- Ferrari Alize J.
- Ferreira Manuela L.
- Feyissa Garumma Tolu
- Filip Irina
- Fischer Florian
- Fisher James L.
- Fitzgerald Ryan
- Flohr Carsten
- Flor Luisa Sorio
- Foigt Nataliya A.
- Folayan Morenike Oluwatoyin
- Fomenkov Artem Alekseevich
- Force Lisa M.
- Fornari Carla
- Forooshani Zahra Sadat Dibaji
- Foroutan Masoud
- Fox Jack T.
- Francis Joel Msafiri
- Frank Tahvi D.
- Franklin Richard Charles
- Freitas Marisa
- Fu Weijia
- Fukumoto Takeshi
- Fukutaki Kai
- Fuller John E.
- Fullman Nancy
- Furtado Joao M.
- Gad Mohamed M.
- Gaidhane Abhay Motiramji
- Gakidou Emmanuela
- Galles Natalie C.
- Gallus Silvano
- Gamkrelidze Amiran
- Garcia-Basteiro Alberto L.
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- Geberemariyam Biniyam Sahiledengle
- Gebrehiwot Abiyu Mekonnen
- Gebremedhin Ketema Bizuwork
- Gebremeskel Gebreamlak Gebremedhn
- Gebremeskel Leake G.
- Gebresillassie Begashaw Melaku
- Gebreslassie Assefa Ayalew Ayalew Ayalew
- Gela Jiregna Darega
- Geramo Yilma Chisha Dea
- Geremew Abraham
- Gesesew Hailay Abrha
- Gething Peter W.
- Gezae Kebede Embaye
- Ghadimi Maryam
- Ghadiri Keyghobad
- Ghaffarifar Fatemeh
- Ghafourifard Mansour
- Ghajar Alireza
- Ghamari Farhad
- Ghashghaee Ahmad
- Ghiasvand Hesam
- Ghith Nermin
- Gholamian Asadollah
- Ghosh Rakesh
- Giampaoli Simona
- Gilani Syed Amir
- Gill Paramjit Singh
- Gill Tiffany K.
- Gillum Richard F.
- Ginawi Ibrahim Abdelmageed
- Ginindza Themba G.
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- Giussani Giorgia
- Glagn Mustefa
- Glushkova Ekaterina Vladimirovna
- Gnedovskaya Elena V.
- Godinho Myron Anthony
- Goharinezhad Salime
- Golechha Mahaveer
- Goli Srinivas
- Gomez Ricardo Santiago
- Gona Philimon N.
- Gopalani Sameer Vali
- Goren Emily
- Gorini Giuseppe
- Gorman Taren M.
- Gottlich Harrison Chase
- Goudarzi Houman
- Goudarzian Amir Hossein
- Goulart Alessandra C.
- Goulart Barbara Niegia Garcia
- Grada Ayman
- Greaves Felix
- Grivna Michal
- Grosso Giuseppe
- Gubari Mohammed Ibrahim Mohialdeen
- Gudi Nachiket
- Gugnani Harish Chander
- Guimaraes Andre Luiz Sena
- Guimaraes Rafael Alves
- Guled Rashid Abdi
- Gultie Teklemariam
- Guo Gaorui
- Guo Yuming
- Gupta Rahul
- Gupta Rajeev
- Gupta Tarun
- Haagsma Juanita A.
- Hachinski Vladimir
- Haddock Beatrix
- Hafezi-Nejad Nima
- Hafiz Abdul
- Hagins Hailey
- Haile Lydia M.
- Haile Teklehaimanot Gereziher
- Haj-Mirzaian Arvin
- Haj-Mirzaian Arya
- Hall Brian J.
- Halvaei Iman
- Hamadeh Randah R.
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- Hamidi Samer
- Hamilton Erin B.
- Hammer Melanie S.
- Han Chieh
- Han Hannah
- Handiso Demelash Woldeyohannes
- Hanif Asif
- Hankey Graeme J.
- Hanson Sarah Wulf
- Haririan Hamidreza
- Haro Josep Maria
- Harvey James D.
- Hasaballah Ahmed I.
- Hasan Md Mehedi
- Hasanpoor Edris
- Hasanzadeh Amir
- Hashemian Maryam
- Hashi Abdiwahab
- Hassan Amr
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- Hassankhani Hadi
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- Hawariat Feleke Gebremeskel W.
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- Hayat Khezar
- Hayoon Anna Gershberg
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- Heidari Behnam
- Heidari Golnaz
- Heidari-Soureshjani Reza
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- Henny Kiana
- Henok Andualem
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- Heydarpour Fatemeh
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- Hoek Hans W.
- Hole Michael K.
- Holla Ramesh
- Hollingsworth Bruce
- Hoogar Praveen
- Hopf Kathleen Pillsbury
- Horita Nobuyuki
- Hosgood H. Dean
- Hossain Naznin
- Hosseini Mostafa
- Hosseinzadeh Mehdi
- Hostiuc Mihaela
- Hostiuc Sorin
- Househ Mowafa
- Hoy Damian G.
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- Hsiao Thomas
- Hsieh Vivian Chia-Rong
- Hu Guoqing
- Hu Kejia
- Huda Tanvir M.
- Hugo Fernando N.
- Humayun Ayesha
- Hussain Rabia
- Huynh Chantal K.
- Hwang Bing-Fang
- Iannucci Vincent C.
- Iavicoli Ivo
- Ibeneme Charles Ugochukwu
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- Ikeda Nayu
- Ikuta Kevin S.
- Il Shin Jae
- Ilesanmi Olayinka Stephen
- Ilic Irena M.
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- Imani-Nasab Mohammad Hasan
- Inbaraj Leeberk Raja
- Ippolito Helen
- Iqbal Usman
- Irvani Seyed Sina Naghibi
- Irvine Caleb Mackay Salpeter
- Islam M. Mofizul
- Islam MdMohaimenul
- Islam Sheikh Mohammed Shariful
- Islami Farhad
- Iso Hiroyasu
- Ivers Rebecca Q.
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- Iwu Chinwe Juliana
- Iyamu Ihoghosa Osamuyi
- Jaafari Jalil
- Jabbari Seyed Hossein Yahyazadeh
- Jacobsen Kathryn H.
- Jadidi-Niaragh Farhad
- Jafarabadi Mohammad Asghari
- Jafari Hussain
- Jafarinia Morteza
- Jahagirdar Deepa
- Jahani Mohammad Ali
- Jahanmehr Nader
- Jakovljevic Mihajlo
- Jalali Amir
- Jalilian Farzad
- James Spencer L.
- Janjani Hosna
- Janodia Manthan Dilipkumar
- Javaheri Tahereh
- Javidnia Javad
- Jayatilleke Achala Upendra
- Jeemon Panniyammakal
- Jenabi Ensiyeh
- Jha Ravi Prakash
- Jha Vivekanand
- Ji John S.
- Jia Peng
- Johansson Lars
- John Oommen
- John-Akinola Yetunde O.
- Johnson Catherine Owens
- Johnson Sarah Charlotte
- Jonas Jost B.
- Joo Tamas
- Joshi Ankur
- Joukar Farahnaz
- Jozwiak Jacek Jerzy
- Jurisson Mikk
- Kabir Ali
- Kabir Zubair
- Kafil Hossein Samadi
- Kalan Mohammad Ebrahimi
- Kalani Hamed
- Kalani Rizwan
- Kalankesh Leila R.
- Kalhor Rohollah
- Kalhori Reza Pourmirza
- Kamath Aruna M.
- Kamiab Zahra
- Kanchan Tanuj
- Kapoor Neeti
- Karanikolos Marina
- Karch Andre
- Karim Mohd Anisul
- Karimi Salah Eddin
- Karimi Seyed Asaad
- Karimi Seyed M.
- Karyani Ali Kazemi
- Kasa Ayele Semachew
- Kassa Getachew Mullu
- Kassebaum Nicholas J.
- Katikireddi Srinivasa Vittal
- Kawakami Norito
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- Keddie Suzanne H.
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- Kereselidze Maia
- Khader Yousef Saleh
- Khafaie Morteza Abdullatif
- Khalid Nauman
- Khammarnia Mohammad
- Khan Ejaz Ahmad
- Khan Gulfaraz
- Khan Maseer
- Khaneghah Amin Mousavi
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- Khatab Khaled
- Khater Amir M.
- Khater Mona M.
- Khatib Mahalaqua Nazli
- Khayamzadeh Maryam
- Khazaei Salman
- Khazaie Habibolah
- Khodayari Mohammad Taghi
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- Khubchandani Jagdish
- Khundkar Roba
- Kianipour Neda
- Kieling Christian
- Kim Cho-Il
- Kim Daniel
- Kim Young-Eun
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- Kimokoti Ruth W.
- Kinfu Yohannes
- Kisa Adnan
- Kisa Sezer
- Kissimova-Skarbek Katarzyna
- Kissoon Niranjan
- Kivimaki Mika
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- Knight Megan
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- Kochhar Sonali
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- Kolola Tufa
- Komaki Hamidreza
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- Korotkova Anna V.
- Korshunov Vladimir Andreevich
- Kosen Soewarta
- Kotlo Anirudh
- Koul Parvaiz A.
- Koyanagi Ai
- Kraemer Moritz U. G.
- Kravchenko Michael A.
- Krishan Kewal
- Krohn Kris J.
- Kromhout Hans
- Kugbey Nuworza
- Kulkarni Vaman
- Kumar G. Anil
- Kumar Manasi
- Kumar Nithin
- Kumar Pushpendra
- Kumar Vivek
- Kumaresh Girikumar
- Kurmi Om P.
- Kusuma Dian
- Kyu Hmwe Hmwe
- La Vecchia Carlo
- Lacey Ben
- Lal Dharmesh Kumar
- Lalloo Ratilal
- Lallukka Tea
- Lam Jennifer O.
- Lami Faris Hasan
- Lan Qing
- Landires Ivan
- Lang Justin J.
- Langan Sinead M.
- Lansingh Van Charles
- Lansky Sonia
- Larson Heidi Jane
- Larson Samantha Leigh
- Larsson Anders
- Lasrado Savita
- Lassi Zohra S.
- Lau Kathryn Mei-Ming
- Lauriola Paolo
- Lavados Pablo M.
- Lazarus Jeffrey V.
- Leal Lisiane F.
- Leasher Janet L.
- Lebni Javad Yoosefi
- Ledesma Jorge R.
- Lee Paul H.
- Lee Shaun Wen Huey
- Leever Andrew T.
- LeGrand Kate E.
- Leigh James
- Leonardi Matilde
- Lescinsky Haley
- Leung Janni
- Levi Miriam
- Lewington Sarah
- Li Bingyu
- Li Shanshan
- Lim Lee-Ling
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- Zheleva Bistra
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- Zhou Maigeng
- Zhu Cong
- Ziapour Arash
- Zimsen Stephanie R. M.
- Zlavog Bianca S.
- Zodpey Sanjay
- Publication venue
- Publication date
- 01/01/2020
- Field of study
Background: In an era of shifting global agendas and expanded emphasis on non-communicable diseases and injuries along with communicable diseases, sound evidence on trends by cause at the national level is essential. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) provides a systematic scientific assessment of published, publicly available, and contributed data on incidence, prevalence, and mortality for a mutually exclusive and collectively exhaustive list of diseases and injuries. Methods: GBD estimates incidence, prevalence, mortality, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life-years (DALYs) due to 369 diseases and injuries, for two sexes, and for 204 countries and territories. Input data were extracted from censuses, household surveys, civil registration and vital statistics, disease registries, health service use, air pollution monitors, satellite imaging, disease notifications, and other sources. Cause-specific death rates and cause fractions were calculated using the Cause of Death Ensemble model and spatiotemporal Gaussian process regression. Cause-specific deaths were adjusted to match the total all-cause deaths calculated as part of the GBD population, fertility, and mortality estimates. Deaths were multiplied by standard life expectancy at each age to calculate YLLs. A Bayesian meta-regression modelling tool, DisMod-MR 2.1, was used to ensure consistency between incidence, prevalence, remission, excess mortality, and cause-specific mortality for most causes. Prevalence estimates were multiplied by disability weights for mutually exclusive sequelae of diseases and injuries to calculate YLDs. We considered results in the context of the Socio-demographic Index (SDI), a composite indicator of income per capita, years of schooling, and fertility rate in females younger than 25 years. Uncertainty intervals (UIs) were generated for every metric using the 25th and 975th ordered 1000 draw values of the posterior distribution. Findings: Global health has steadily improved over the past 30 years as measured by age-standardised DALY rates. After taking into account population growth and ageing, the absolute number of DALYs has remained stable. Since 2010, the pace of decline in global age-standardised DALY rates has accelerated in age groups younger than 50 years compared with the 1990–2010 time period, with the greatest annualised rate of decline occurring in the 0–9-year age group. Six infectious diseases were among the top ten causes of DALYs in children younger than 10 years in 2019: lower respiratory infections (ranked second), diarrhoeal diseases (third), malaria (fifth), meningitis (sixth), whooping cough (ninth), and sexually transmitted infections (which, in this age group, is fully accounted for by congenital syphilis; ranked tenth). In adolescents aged 10–24 years, three injury causes were among the top causes of DALYs: road injuries (ranked first), self-harm (third), and interpersonal violence (fifth). Five of the causes that were in the top ten for ages 10–24 years were also in the top ten in the 25–49-year age group: road injuries (ranked first), HIV/AIDS (second), low back pain (fourth), headache disorders (fifth), and depressive disorders (sixth). In 2019, ischaemic heart disease and stroke were the top-ranked causes of DALYs in both the 50–74-year and 75-years-and-older age groups. Since 1990, there has been a marked shift towards a greater proportion of burden due to YLDs from non-communicable diseases and injuries. In 2019, there were 11 countries where non-communicable disease and injury YLDs constituted more than half of all disease burden. Decreases in age-standardised DALY rates have accelerated over the past decade in countries at the lower end of the SDI range, while improvements have started to stagnate or even reverse in countries with higher SDI. Interpretation: As disability becomes an increasingly large component of disease burden and a larger component of health expenditure, greater research and developm nt investment is needed to identify new, more effective intervention strategies. With a rapidly ageing global population, the demands on health services to deal with disabling outcomes, which increase with age, will require policy makers to anticipate these changes. The mix of universal and more geographically specific influences on health reinforces the need for regular reporting on population health in detail and by underlying cause to help decision makers to identify success stories of disease control to emulate, as well as opportunities to improve. Funding: Bill & Melinda Gates Foundation. © 2020 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 licens
Muon reconstruction and identification efficiency in ATLAS using the full Run 2 pp collision data set at \sqrt{s}=13 TeV
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- Zhemchugov A
- Zheng Z
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- Zorbas TG
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- Zwalinski L
- Publication venue
- 'Springer Fachmedien Wiesbaden GmbH'
- Publication date
- 01/01/2021
- Field of study
This article documents the muon reconstruction and identification efficiency obtained by the ATLAS experiment for 139 \hbox {fb}^{-1} of pp collision data at \sqrt{s}=13 TeV collected between 2015 and 2018 during Run 2 of the LHC. The increased instantaneous luminosity delivered by the LHC over this period required a reoptimisation of the criteria for the identification of prompt muons. Improved and newly developed algorithms were deployed to preserve high muon identification efficiency with a low misidentification rate and good momentum resolution. The availability of large samples of Z\rightarrow \mu \mu and J/\psi \rightarrow \mu \mu decays, and the minimisation of systematic uncertainties, allows the efficiencies of criteria for muon identification, primary vertex association, and isolation to be measured with an accuracy at the per-mille level in the bulk of the phase space, and up to the percent level in complex kinematic configurations. Excellent performance is achieved over a range of transverse momenta from 3 GeV to several hundred GeV, and across the full muon detector acceptance of |\eta |<2.7
Combination of searches for heavy spin-1 resonances using 139 fb−1 of proton-proton collision data at s = 13 TeV with the ATLAS detector
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- Zenin O
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- Zhang Z
- Zhao H
- Zhao T
- Zhao Y
- Zhao Z
- Zhao Z
- Zhemchugov A
- Zheng J
- Zheng K
- Zheng X
- Zheng Z
- Zhong D
- Zhou B
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- Zhukov K
- Zimine NI
- Zinsser J
- Ziolkowski M
- Zoccoli A
- Zoch K
- Zorbas TG
- Zormpa O
- Zou W
- Zwalinski L
- Åkesson TPA
- Öncel ÖO
- Ženiš T
- Živković L
- Publication venue
- Springer Nature
- Publication date
- 19/04/2024
- Field of study
A combination of searches for new heavy spin-1 resonances decaying into different pairings of W, Z, or Higgs bosons, as well as directly into leptons or quarks, is presented. The data sample used corresponds to 139 fb−1 of proton-proton collisions at
= 13 TeV collected during 2015–2018 with the ATLAS detector at the CERN Large Hadron Collider. Analyses selecting quark pairs (qq, bb,
, and tb) or third-generation leptons (τν and ττ) are included in this kind of combination for the first time. A simplified model predicting a spin-1 heavy vector-boson triplet is used. Cross-section limits are set at the 95% confidence level and are compared with predictions for the benchmark model. These limits are also expressed in terms of constraints on couplings of the heavy vector-boson triplet to quarks, leptons, and the Higgs boson. The complementarity of the various analyses increases the sensitivity to new physics, and the resulting constraints are stronger than those from any individual analysis considered. The data exclude a heavy vector-boson triplet with mass below 5.8 TeV in a weakly coupled scenario, below 4.4 TeV in a strongly coupled scenario, and up to 1.5 TeV in the case of production via vector-boson fusion
- …