16 research outputs found
Upper ocean carbon fluxes in the Atlantic Ocean: The importance of the POC:PIC ratio
The mean depth distribution of the POC:PIC ratio of sinking particles, measured with particle interceptor traps deployed in the Atlantic Ocean, is fitted by an exponential function (POC:PIC = 64.3Z−0.56; r2 = 0.69) The function is successfully evaluated by comparison with (a) estimates of the POC:PIC ratio of export production, computed from seasonal changes of nitrate and alkalinity and (b) estimates of the POC:PIC ratio of remineralization on shallow isopycnals. The basin mean POC:PIC ratio of export production is 4.2–4.37. The POC:PIC-depth function is combined with empirical relationships between the flux of particulate organic matter, primary production and depth, satellite derived primary production data sets, and the regional distribution of ψ (the ratio of released CO2:precipitated carbonate during CaCO3 formation) in order to estimate the effective carbon flux (Jeff) in the Atlantic Ocean. Remineralization of organic carbon above the winter mixed layer (11–17%) and CaCO3 sequestration from the winter mixed layer (13–16%), which is the balance between CaCO3 production and shallow dissolution, are the two main processes which control the difference between export production (0.9 and 2.9 GT C yr−1) and Jeff (0.64 and 2.2 GT C yr−1) on the basin scale (65°N to 65°S). CaCO3 sequestration is the dominant process modulating effective carbon export in the tropics, while shallow POC remineralization dominates in temperate and polar waters. Observed regional patterns like polarward increases of the POC:PIC export ratio and of ψ counteract each other largely when Jeff is computed
Ghrelin
This work was supported by grants from the NIH (DP2DK105570-01 and
2P30DK046200 to MLA, DK21397 to HJG, K01DK098319 to KMH, K01MH091222 to
LH, DK093848 to RJS, R01DK082590 to LS, R01DK097550 to JT, RO1 DK 076037 to
MOT, R01DA024680 and R01MH085298 to JMZ, R01AG019230 and R01AG029740
to RGS) The Wellcome Trust (MK), Science Foundation Ireland (12/YI/B2480 to CWL),
the Alexander von Humboldt Foundation (MHT), the Deutsches Zentrum für Diabetesforschung
(MHT), the Helmholtz Alliance ICEMED e Imaging and Curing
Environmental Metabolic Diseases, through the Initiative and Networking Fund of the
Helmholtz Association (MHT), and the Helmholtz cross-program topic “Metabolic
Dysfunction” (MHT). Allan Geliebter was sponsored by NIH grants R01DK80153;
R01DK074046; R03DK068603; P30DK26687
Algemene Inleiding op de Wet Bibob
De Wet Bibob is bedoeld als een van de instrumenten om dit probleem aan te pakken. In deze wet wordt gekozen voor een bestuursrechtelijke aanpak, naast het bestaande strafrechtelijke instrumentarium. Op grond van deze wet kan het bestuursorgaan beschikkingen weigeren of intrekken, indien gevaar bestaat dat deze worden gebruikt voor criminele activiteiten. In dit algemene deel wordt, als inleiding op de preadviezen, de aanleiding van deze wet en de wetsystematiek globaal beschreven. Deze beschrijving mondt uit in een aantal vragen en aandachtspunten, die in de preadviezen worden behandeld.
Het preadvies 'Instrumentele waarde van de Wet Bibob' is eveneens in de repository geplaatst.
Liver perfusion in dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI): comparison of enhancement in Gd-BT-DO3A and Gd-EOB-DTPA in normal liver parenchyma
The continuous infusion of acylated ghrelin enhances growth hormone secretion and worsens glucose metabolism in humans
Millennial-scale variability in Red Sea circulation in response to Holocene insolation forcing
In order to assess how insolation-driven climate change superimposed on sea level rise and millennial events influenced the Red Sea during the Holocene, we present new paleoceanographic records from two sediment cores to develop a comprehensive reconstruction of Holocene circulation dynamics in the basin. We show that the recovery of the planktonic foraminiferal fauna after the Younger Dryas was completed earlier in the northern than in the central Red Sea, implying significant changes in the hydrological balance of the northern Red Sea region during the deglaciation. In the early part of the Holocene, the environment of the Red Sea closely followed the development of the Indian summer monsoon and was dominated by a circulation mode similar to the current summer circulation, with low productivity throughout the central and northern Red Sea. The climatic signal during the late Holocene is dominated by a faunal transient event centered around 2.4 ka BP. Its timing corresponds to that of North Atlantic Bond event 2 and to a widespread regionally recorded dry period. This faunal transient is characterized by a more productive foraminiferal fauna and can be explained by an intensification of the winter circulation mode and high evaporation. The modern distribution pattern of planktonic foraminifera, reflecting the prevailing circulation system, was established after 1.7 ka BP