Black Hole Production from High Energy Scattering in AdS/CFT

In this article we show how to set up initial states in ${\cal N} =4$ SYM theory that correspond to high energy graviton collisions, leading to black hole formation in $AdS_5\times S^5$. For this purpose, we study states in the gauge theory that are dual to graviton wavepackets localized at the center of $AdS_5$, and carrying large angular momentum along the $S^5$. These states are created by exciting only the s-wave mode of one of the complex adjoint scalars of SYM. For a single graviton, the state is 1/2 BPS and one can show that it is dual to a linearized 1/2 BPS geometry in the bulk. Exploiting this dictionary, we show how to localize the particle's wavefunciton so that the dual linearized metric has the form of a Aichelburg-Sexl shock wave. One can then put two such shock waves into a head-on collision, which is known to produce a trapped surface. Finally, we discuss the prospect of studying graviton scattering directly at strong coupling in the gauge theory using a reduced model of matrix quantum mechanics.Comment: 11 pages, revtex format, no figure

Emergent Classical Strings from Matrix Model

Generalizing the idea of hep-th/0509015 by Berenstein, Correa, and Vazquez, we study many-magnon states in an SU(2) sector of a reduced matrix quantum mechanics obtained from N=4 SU(N) super Yang-Mills on R x S^3. Generic Q-magnon states are described as a chain of ``string-bits'' joining Q+1 eigenvalues of background matrices which form a 1/2 BPS circular droplet in the large N limit. We will concentrate on infinitely long states whose first and last eigenvalues localize at the edge of the droplet. Each constituent string-bit has a complex quasi-momentum in general, while the total quasi-momentum P of the state is real. For given Q and P, the minimum energy of the chain of string-bits is realized when the Q+1 eigenvalues are equally spaced on one and the same line segment joining the two outmost eigenvalues localized on the edge with angular difference P. Such configuration of bound string-bits precisely reproduces the dispersion relation for dyonic giant magnons in classical string theory. We also show the emergence of two-spin folded/circular strings in special infinite spin limit as particular configurations of closed chains of string-bits.Comment: 1+23 pages, 3 figure

Strings on conifolds from strong coupling dynamics, part I

A method to solve various aspects of the strong coupling expansion of the superconformal field theory duals of AdS_5 x X geometries from first principles is proposed. The main idea is that at strong coupling the configurations that dominate the low energy dynamics of the field theory compactified on a three sphere are given by certain non-trivial semi-classical configurations in the moduli space of vacua. We show that this approach is self-consistent and permits one to express most of the dynamics in terms of an effective N=4 SYM dynamics. This has the advantage that some degrees of freedom that move the configurations away from moduli space can be treated perturbatively, unifying the essential low energy dynamics of all of these theories. We show that with this formalism one can compute the energies of strings in the BMN limit in the Klebanov-Witten theory from field theory considerations, matching the functional form of results found using AdS geometry. This paper also presents various other technical results for the semiclassical treatment of superconformal field theories.Comment: 52 pages, JHEP3 styl

Gravitational Lensing by Black Holes

We review the theoretical aspects of gravitational lensing by black holes, and discuss the perspectives for realistic observations. We will first treat lensing by spherically symmetric black holes, in which the formation of infinite sequences of higher order images emerges in the clearest way. We will then consider the effects of the spin of the black hole, with the formation of giant higher order caustics and multiple images. Finally, we will consider the perspectives for observations of black hole lensing, from the detection of secondary images of stellar sources and spots on the accretion disk to the interpretation of iron K-lines and direct imaging of the shadow of the black hole.Comment: Invited article for the GRG special issue on lensing (P. Jetzer, Y. Mellier and V. Perlick Eds.). 31 pages, 12 figure

Search for direct production of charginos and neutralinos in events with three leptons and missing transverse momentum in √s = 7 TeV pp collisions with the ATLAS detector

A search for the direct production of charginos and neutralinos in final states with three electrons or muons and missing transverse momentum is presented. The analysis is based on 4.7 fb−1 of proton–proton collision data delivered by the Large Hadron Collider and recorded with the ATLAS detector. Observations are consistent with Standard Model expectations in three signal regions that are either depleted or enriched in Z-boson decays. Upper limits at 95% confidence level are set in R-parity conserving phenomenological minimal supersymmetric models and in simplified models, significantly extending previous results

Jet size dependence of single jet suppression in lead-lead collisions at sqrt(s(NN)) = 2.76 TeV with the ATLAS detector at the LHC

Measurements of inclusive jet suppression in heavy ion collisions at the LHC provide direct sensitivity to the physics of jet quenching. In a sample of lead-lead collisions at sqrt(s) = 2.76 TeV corresponding to an integrated luminosity of approximately 7 inverse microbarns, ATLAS has measured jets with a calorimeter over the pseudorapidity interval |eta| < 2.1 and over the transverse momentum range 38 < pT < 210 GeV. Jets were reconstructed using the anti-kt algorithm with values for the distance parameter that determines the nominal jet radius of R = 0.2, 0.3, 0.4 and 0.5. The centrality dependence of the jet yield is characterized by the jet "central-to-peripheral ratio," Rcp. Jet production is found to be suppressed by approximately a factor of two in the 10% most central collisions relative to peripheral collisions. Rcp varies smoothly with centrality as characterized by the number of participating nucleons. The observed suppression is only weakly dependent on jet radius and transverse momentum. These results provide the first direct measurement of inclusive jet suppression in heavy ion collisions and complement previous measurements of dijet transverse energy imbalance at the LHC.Comment: 15 pages plus author list (30 pages total), 8 figures, 2 tables, submitted to Physics Letters B. All figures including auxiliary figures are available at http://atlas.web.cern.ch/Atlas/GROUPS/PHYSICS/PAPERS/HION-2011-02

The impact of the metabotropic glutamate receptor and other gene family interaction networks on autism

Although multiple reports show that defective genetic networks underlie the aetiology of autism, few have translated into pharmacotherapeutic opportunities. Since drugs compete with endogenous small molecules for protein binding, many successful drugs target large gene families with multiple drug binding sites. Here we search for defective gene family interaction networks (GFINs) in 6,742 patients with the ASDs relative to 12,544 neurologically normal controls, to find potentially druggable genetic targets. We find significant enrichment of structural defects (P≤2.40E-09, 1.8-fold enrichment) in the metabotropic glutamate receptor (GRM) GFIN, previously observed to impact attention deficit hyperactivity disorder (ADHD) and schizophrenia. Also, the MXD-MYC-MAX network of genes, previously implicated in cancer, is significantly enriched (P≤3.83E-23, 2.5-fold enrichment), as is the calmodulin 1 (CALM1) gene interaction network (P≤4.16E-04, 14.4-fold enrichment), which regulates voltage-independent calcium-activated action potentials at the neuronal synapse. We find that multiple defective gene family interactions underlie autism, presenting new translational opportunities to explore for therapeutic interventions

Autoantibodies against type I IFNs in patients with life-threatening COVID-19

Interindividual clinical variability in the course of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is vast. We report that at least 101 of 987 patients with life-threatening coronavirus disease 2019 (COVID-19) pneumonia had neutralizing immunoglobulin G (IgG) autoantibodies (auto-Abs) against interferon-w (IFN-w) (13 patients), against the 13 types of IFN-a (36), or against both (52) at the onset of critical disease; a few also had auto-Abs against the other three type I IFNs. The auto-Abs neutralize the ability of the corresponding type I IFNs to block SARS-CoV-2 infection in vitro. These auto-Abs were not found in 663 individuals with asymptomatic or mild SARS-CoV-2 infection and were present in only 4 of 1227 healthy individuals. Patients with auto-Abs were aged 25 to 87 years and 95 of the 101 were men. A B cell autoimmune phenocopy of inborn errors of type I IFN immunity accounts for life-threatening COVID-19 pneumonia in at least 2.6% of women and 12.5% of men

Measurement of prompt hadron production ratios in pppp collisions at s=\sqrt{s} = 0.9 and 7 TeV

The charged-particle production ratios $\bar{p}/p$, $K^-/K^+$, $\pi^-/\pi^+$, $(p + \bar{p})/(\pi^+ + \pi^-)$, $(K^+ + K^-)/(\pi^+ + \pi^-)$ and $(p + \bar{p})/(K^+ + K^-)$ are measured with the LHCb detector using $0.3 {\rm nb^{-1}}$ of $pp$ collisions delivered by the LHC at $\sqrt{s} = 0.9$ TeV and $1.8 {\rm nb^{-1}}$ at $\sqrt{s} = 7$ TeV. The measurements are performed as a function of transverse momentum $p_{\rm T}$ and pseudorapidity $\eta$. The production ratios are compared to the predictions of several Monte Carlo generator settings, none of which are able to describe adequately all observables. The ratio $\bar{p}/p$ is also considered as a function of rapidity loss, $\Delta y \equiv y_{\rm beam} - y$, and is used to constrain models of baryon transport.Comment: Incorrect entries in Table 2 corrected. No consequences for rest of pape