Conformal and Nonconformal Symmetries in 2d Dilaton gravity

We study finite-dimensional extra symmetries of generic 2D dilaton gravity models. Using a non-linear sigma model formulation we show that the unique theories admitting an extra (conformal) symmetry are the models with an exponential potential $V \propto e^{\beta\phi}$ ($S ={1\over2\pi} \int d^2 x \sqrt{-g} [ R \phi + 4 \lambda^2 e^{\beta\phi} ]$), which include the CGHS model as a particular though limiting ($\beta=0$) case. These models give rise to black hole solutions with a mass-dependent temperature. The underlying extra symmetry can be maintained in a natural way in the one-loop effective action, thus implying the exact solubility of the semiclassical theory including back-reaction. Moreover, we also introduce three different classes of (non-conformal) transformations which are extra symmetries for generic 2D dilaton gravity models. Special linear combinations of these transformations turn out to be the (conformal) symmetries of the CGHS and $V \propto e^{\beta\phi}$ models. We show that one of the non-conformal extra symmetries can be converted into a conformal one by means of adequate field redefinitions involving the metric and the derivatives of the dilaton. Finally, by expressing the Polyakov-Liouville effective action in terms of an invariant metric, we are able to provide semiclassical models which are also invariant. This generalizes the solvable semiclassical model of Bose, Parker and Peleg (BPP) for a generic 2D dilaton gravity model.Comment: Latex, no figures. Revised version published i

Symmetries and solvable models for evaporating 2D black holes

We study the evaporation process of a 2D black hole in thermal equilibrium when the ingoing radiation is switched off suddenly. We also introduce global symmetries of generic 2D dilaton gravity models which generalize the extra symmetry of the CGHS model.Comment: 4 pages, Latex. Talk given at the Second Conference on Quantum Gravity and Constrained Dynamics. To appear in Proc. Supp. Nucl. Phys.

Weyl Invariance and Black Hole Evaporation

We consider the semiclassical dynamics of CGHS black holes with a Weyl-invariant effective action for conformal matter. The trace anomaly of Polyakov effective action is converted into the Virasoro anomaly thus leading to the same flux of Hawking radiation. The covariance of semiclassical equations can be restored through a non-local redefinition of the metric-dilaton fields. The resulting theory turns out to be equivalent to the RST model. This provides a mechanism to solve semiclassical equations of 2D dilaton gravity coupled to conformal matter for classically soluble models.Comment: LaTeX, needs amssymb, 8 pages. One reference adde

Production of entanglement in Raman three-level systems using feedback

We examine the theoretical limits of the generation of entanglement in a damped coupled ion-cavity system using jump-based feedback. Using Raman transitions to produce entanglement between ground states reduces the necessary feedback bandwidth, but does not improve the overall effect of the spontaneous emission on the final entanglement. We find that the fidelity of the resulting entanglement will be limited by the asymmetries produced by vibrations in the trap, but that the concurrence remains above 0.88 for realistic ion trap sizes.Comment: 8 pages, 8 figure

Electron/pion separation with an Emulsion Cloud Chamber by using a Neural Network

We have studied the performance of a new algorithm for electron/pion separation in an Emulsion Cloud Chamber (ECC) made of lead and nuclear emulsion films. The software for separation consists of two parts: a shower reconstruction algorithm and a Neural Network that assigns to each reconstructed shower the probability to be an electron or a pion. The performance has been studied for the ECC of the OPERA experiment [1]. The $e/\pi$ separation algorithm has been optimized by using a detailed Monte Carlo simulation of the ECC and tested on real data taken at CERN (pion beams) and at DESY (electron beams). The algorithm allows to achieve a 90% electron identification efficiency with a pion misidentification smaller than 1% for energies higher than 2 GeV

Scientific and regulatory evaluation of mechanistic in silico drug and disease models in drug development: building model credibility

The value of in silico methods in drug development and evaluation has been demonstrated repeatedly and convincingly. While their benefits are now unanimously recognized, international standards for their evaluation, accepted by all stakeholders involved, are still to be established. In this white paper, we propose a risk-informed evaluation framework for mechanistic model credibility evaluation. To properly frame the proposed verification and validation activities, concepts such as context of use, regulatory impact and risk-based analysis are discussed. To ensure common understanding between all stakeholders, an overview is provided of relevant in silico terminology used throughout this paper. To illustrate the feasibility of the proposed approach, we have applied it to three real case examples in the context of drug development, using a credibility matrix currently being tested as a quick-start tool by regulators. Altogether, this white paper provides a practical approach to model evaluation, applicable in both scientific and regulatory evaluation contexts

Descriptors of Posidonia oceanica meadows: Use and application

The conservation of the coastal marine environment requires the possession of information that enables the global quality of the environment to be evaluated reliably and relatively quickly. The use of biological indicators is often an appropriate method. Seagrasses in general, and Posidonia oceanica meadows in particular, are considered to be appropriate for biomonitoring because of their wide distribution, reasonable size, sedentary habit, easy collection and abundance and sensitivity to modifications of littoral zone. Reasoned management, on the scale of the whole Mediterranean basin, requires standardized methods of study, to be applied by both researchers and administrators, enabling comparable results to be obtained. This paper synthesises the existing methods applied to monitor P. oceanica meadows, identifies the most suitable techniques and suggests future research directions. From the results of a questionnaire, distributed to all the identified laboratories working on this topic, a list of the most commonly used descriptors was drawn up, together with the related research techniques (e.g. standardization, interest and limits, valuation of the results). It seems that the techniques used to study meadows are rather similar, but rarely identical, even though the various teams often refer to previously published works. This paper shows the interest of a practical guide that describes, in a standardized way, the most useful techniques enabling P. oceanica meadows to be used as an environmental descriptor. Indeed, it constitutes the first stage in the process. (c) 2005 Elsevier Ltd. All rights reserved.Peer reviewe

Need for speed: Examining protein behavior during cryoEM grid preparation at different timescales

A host of new technologies are under development to improve the quality and reproducibility of cryoelectron microscopy (cryoEM) grid preparation. Here we have systematically investigated the preparation of three macromolecular complexes using three different vitrification devices (Vitrobot, chameleon, and a time-resolved cryoEM device) on various timescales, including grids made within 6 ms (the fastest reported to date), to interrogate particle behavior at the air-water interface for different timepoints. Results demonstrate that different macromolecular complexes can respond to the thin-film environment formed during cryoEM sample preparation in highly variable ways, shedding light on why cryoEM sample preparation can be difficult to optimize. We demonstrate that reducing time between sample application and vitrification is just one tool to improve cryoEM grid quality, but that it is unlikely to be a generic “silver bullet” for improving the quality of every cryoEM sample preparation

Search for black holes and other new phenomena in high-multiplicity final states in proton-proton collisions at root s=13 TeV

Peer reviewe

Track A Basic Science

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/138319/1/jia218438.pd