24 research outputs found
Sociomateriality Implications of Software As a Service Adoption on IT-workers’ Roles and Changes in Organizational Routines of IT Systems Support
This paper aims to deepen our understanding on how sociomateriality practices influence IT
workers’ roles and skill set requirements and changes to the organizational routines of IT systems support,
when an organization migrates an on-premise IT system to a software as a service (SaaS) model. This
conceptual paper is part of an ongoing study investigating organizations that migrated on-premise IT email
systems to SaaS business models, such as Google Apps for Education (GAE) and Microsoft Office 365
systems, in New Zealand tertiary institutions. We present initial findings from interpretive case studies. The
findings are, firstly, technological artifacts are entangled in sociomaterial practices, which change the way
humans respond to the performative aspects of the organizational routines. Human and material agencies are
interwoven in ways that reinforce or change existing routines. Secondly, materiality, virtual realm and spirit
of the technology provide elementary levels at which human and material agencies entangle. Lastly, the
elementary levels at which human and material entangle depends on the capabilities or skills set of an
individual
Multi-messenger observations of a binary neutron star merger
On 2017 August 17 a binary neutron star coalescence candidate (later designated GW170817) with merger time 12:41:04 UTC was observed through gravitational waves by the Advanced LIGO and Advanced Virgo detectors. The Fermi Gamma-ray Burst Monitor independently detected a gamma-ray burst (GRB 170817A) with a time delay of ~1.7 s with respect to the merger time. From the gravitational-wave signal, the source was initially localized to a sky region of 31 deg2 at a luminosity distance of 40+8-8 Mpc and with component masses consistent with neutron stars. The component masses were later measured to be in the range 0.86 to 2.26 Mo. An extensive observing campaign was launched across the electromagnetic spectrum leading to the discovery of a bright optical transient (SSS17a, now with the IAU identification of AT 2017gfo) in NGC 4993 (at ~40 Mpc) less than 11 hours after the merger by the One- Meter, Two Hemisphere (1M2H) team using the 1 m Swope Telescope. The optical transient was independently detected by multiple teams within an hour. Subsequent observations targeted the object and its environment. Early ultraviolet observations revealed a blue transient that faded within 48 hours. Optical and infrared observations showed a redward evolution over ~10 days. Following early non-detections, X-ray and radio emission were discovered at the transient’s position ~9 and ~16 days, respectively, after the merger. Both the X-ray and radio emission likely arise from a physical process that is distinct from the one that generates the UV/optical/near-infrared emission. No ultra-high-energy gamma-rays and no neutrino candidates consistent with the source were found in follow-up searches. These observations support the hypothesis that GW170817 was produced by the merger of two neutron stars in NGC4993 followed by a short gamma-ray burst (GRB 170817A) and a kilonova/macronova powered by the radioactive decay of r-process nuclei synthesized in the ejecta
Racing the E-Bomb: How the Internet is Redefining Information Systems Development Methodology
Multiparasitism of Piezodorus guildinii eggs by Telenomus podisi and Trissolcus urichi
Multiparasitism involves competition between larvae inside the host. Telenomus podisi (Ashmead) and Trissolcus urichi (Crawford) (Hymenoptera: Platygastridae) are solitary egg parasitoids of Piezodorus guildinii Westwood (Hemiptera: Pentatomidae), an important soybean pest. Egg masses partially parasitized by one species were offered to females of the other species. Both species attacked randomly unparasitized and parasitized hosts. Emergence from multiparasitized eggs was greater for T. urichi than for T. podisi, although it was lower than emergence from eggs parasitized by T. urichi alone. Emergence of each species was independent of the order in which they parasitized and of time elapsed between ovipositions. Progeny sex ratio obtained from multiparasitized and from parasitized eggs were similar for both parasitoids. Our results suggest that T. urichi is a better intrinsic competitor than T. podisi for P. guildinii eggs. In the field, however, T. podisi was the dominant species, and T. urichi could be using other pentatomid eggs as resource.Fil: Cingolani, Maria Fernanda. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico la Plata. Centro de Estudios Parasitológicos y de Vectores (i); Argentina. Universidad Nacional de La Plata; ArgentinaFil: Greco, Nancy Mabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico la Plata. Centro de Estudios Parasitológicos y de Vectores (i); Argentina. Universidad Nacional de La Plata; ArgentinaFil: Liljesthrom, Gerardo Gustavo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico la Plata. Centro de Estudios Parasitológicos y de Vectores (i); Argentina. Universidad Nacional de La Plata; Argentin
Patients’ perceptions of 70-gene signature testing: commonly changing the initial inclination to undergo or forego chemotherapy and reducing decisional conflict
Influence of intraocular lens material on the development of acute endophthalmitis after cataract surgery?
Management and Computer Science Synergies: A Theoretical Framework for Context Sensitive Simulation Environment
In the light of contemporary management trends and on the basis of the theory of “open innovation”, derives the concept of “crossfertilization”. Crossfertilization, i.e. profitable inter-group knowledge exchange facilitates the fusion of input from different disciplinary communities. In such a scenario, the study highlights the opportunities deriving from the cross-fertilization between management and computer science domains, and yields in terms of cognitive synergies results that exceeds by far the individual outputs of the parties involved. The approach we propose is a full mode generation of knowledge starting from the hypothetical assumptions relative to simulation using context data. A general workflow complementary Structural Equation Modeling (SEM) is defining being the most appropriate mathematical technique for testing causal relationships between latent variables with Fuzzy Data Analysis techniques in order to tailor Decision Support System (DSS) to the context of application. The main contribution of our study is the definition of a theoretical framework to address contextual decision making concerning relations between commitment, loyalty and customer satisfaction
Using a gene expression signature when controversy exists regarding the indication for adjuvant systemic treatment reduces the proportion of patients receiving adjuvant chemotherapy : a nationwide study
PURPOSE: The Dutch national guideline advises use of gene-expression signatures, such as the 70-gene signature (70-GS), in case of ambivalence regarding the benefit of adjuvant chemotherapy (CT). In this nationwide study, the impact of 70-GS use on the administration of CT in early breast cancer patients with a dubious indication for CT is assessed. METHODS: Patients within a national guideline directed indication area for 70-GS use who were surgically treated between November 2011 and April 2013 were selected from the Netherlands Cancer Registry database. The effect of 70-GS use on the administration of CT was evaluated in guideline- and age-delineated subgroups addressing potential effect of bias by linear mixed-effect modeling and instrumental variable (IV) analyses. RESULTS: A total of 2,043 patients within the indicated area for 70-GS use were included, of whom 298 received a 70-GS. Without use of the 70-GS, 45% of patients received CT. The 70-GS use was associated with a 9.5% decrease in CT administration (95% confidence interval (CI): -15.7 to -3.3%) in linear mixed-effect model analyses and IV analyses showed similar results (-9.9%; 95% CI: -19.3 to -0.4). CONCLUSION: In patients in whom the Dutch national guidelines suggest the use of a gene-expression profile, 70-GS use is associated with a 10% decrease in the administration of adjuvant CT.Genet Med 18 7, 720-726.Genetics in Medicine (2016); 18 7, 720-726. doi:10.1038/gim.2015.152