272 research outputs found
BUILDING LASTING BONDS: EXPLORING EFFECTIVE EMPLOYEE RETENTION TECHNIQUES IN CONTEMPORARY ORGANIZATIONS
In the context of modern workplace contexts, employee retention is a crucial topic that is explored in this research study. Fostering strong relationships with employees has become essential in firms' quest to keep their competitive advantages. The goal of this study is to identify and evaluate a variety of employee retention tactics that work well in contemporary organizations. This research identifies essential strategies covering professional development, work-life balance, inclusive organizational culture, recognition programs, and flexible benefits through thoroughly examining existing literature and empirical investigation. The results give corporate executives, human resource professionals, and academics useful information that they can use to create complete strategies that will improve employee retention, job satisfaction, and overall organizational performance. Article visualizations
THE IMPACT OF REMOTE WORK ON HR PRACTICES: NAVIGATING CHALLENGES, EMBRACING OPPORTUNITIES
The COVID-19 pandemic has enhanced the rise of remote work, revolutionized organizational operations, and significantly impacted human resources (HR) practices. This paper explores the profound effects of remote work on HR functions, addressing both challenges and opportunities in this new paradigm. The shift to remote work has increased flexibility for the workforce and opened access to a global talent pool. However, it has not been without its challenges for HR professionals. They now face hurdles in engaging employees, managing performance effectively, and promoting team collaboration. Ensuring a unified organizational culture and cultivating a solid connection among remote workers have become pressing concerns. This research emphasizes the significance of HR departments adapting to the realities of remote work. It proposes a need for redefining talent acquisition, training, performance evaluation, and employee engagement strategies. By analyzing real-world case studies and expert insights, this study offers valuable guidance to HR leaders and practitioners in effectively navigating challenges and optimizing remote work arrangements. Embracing remote work provides clear advantages for organizations that enhance resilience and attract top talent. In this regard, HR professionals must proactively adopt technology and acquire new skill sets to optimize remote work environments. As organizations navigate the challenges of remote work, the HR function plays a fundamental role in shaping work's future and nurturing a thriving workforce. This study offers valuable insights, empowering HR practitioners to position their organizations for success amid this evolving landscape. Article visualizations
Inferring high-resolution human mixing patterns for disease modeling
Mathematical and computational modeling approaches are increasingly used as
quantitative tools in the analysis and forecasting of infectious disease
epidemics. The growing need for realism in addressing complex public health
questions is however calling for accurate models of the human contact patterns
that govern the disease transmission processes. Here we present a data-driven
approach to generate effective descriptions of population-level contact
patterns by using highly detailed macro (census) and micro (survey) data on key
socio-demographic features. We produce age-stratified contact matrices for 277
sub-national administrative regions of countries covering approximately 3.5
billion people and reflecting the high degree of cultural and societal
diversity of the focus countries. We use the derived contact matrices to model
the spread of airborne infectious diseases and show that sub-national
heterogeneities in human mixing patterns have a marked impact on epidemic
indicators such as the reproduction number and overall attack rate of epidemics
of the same etiology. The contact patterns derived here are made publicly
available as a modeling tool to study the impact of socio-economic differences
and demographic heterogeneities across populations on the epidemiology of
infectious diseases.Comment: 18 pages, 7 figure
Globally prevalent PfMDR1 mutations modulate Plasmodium falciparum susceptibility to artemisinin-based combination therapies
Antimalarial chemotherapy, globally reliant on artemisinin-based combination therapies (ACTs), is threatened by the spread of drug resistance in Plasmodium falciparum parasites. Here we use zinc-finger nucleases to genetically modify the multidrug resistance-1 transporter PfMDR1 at amino acids 86 and 184, and demonstrate that the widely prevalent N86Y mutation augments resistance to the ACT partner drug amodiaquine and the former first-line agent chloroquine. In contrast, N86Y increases parasite susceptibility to the partner drugs lumefantrine and mefloquine, and the active artemisinin metabolite dihydroartemisinin. The PfMDR1 N86 plus Y184F isoform moderately reduces piperaquine potency in strains expressing an Asian/African variant of the chloroquine resistance transporter PfCRT. Mutations in both digestive vacuole-resident transporters are thought to differentially regulate ACT drug interactions with host haem, a product of parasite-mediated haemoglobin degradation. Global mapping of these mutations illustrates where the different ACTs could be selectively deployed to optimize treatment based on regional differences in PfMDR1 haplotypes.This work was funded in part by the National Institutes of Health (R01 AI50234, AI124678 and AI109023) and a Burroughs Wellcome Fund Investigator in Pathogenesis of Infectious Diseases award to D.A.F. This research also received funding from the Portuguese Fundacao para a Ciencia e Tecnologia (FCT), cofunded by Programa Operacional Regional do Norte (ON.2-O Novo Norte); from the Quadro de Referencia Estrategico Nacional (QREN) through the Fundo Europeu de Desenvolvimento Regional (FEDER) and from the Projeto Estrategico - LA 26 - 2013-2014 (PEst-C/SAU/LA0026/2013). M.I.V. is the recipient of a postdoctoral fellowship from FCT/Ministerio da Ciencia e Ensino Superior, Portugal-MCES (SFRH/BPD/76614/2011). A.M.L. was supported by an Australian National Health and Medical Research Council (NHMRC) Overseas Biomedical Fellowship (585519). R.E.M. was supported by an NHMRC RD Wright Biomedical Fellowship (1053082). A.C.U. was supported by an Irving scholarship from Columbia University. We thank Dr Andrea Ecker for her help with plasmid design and Pedro Ferreira for his expert help with Fig. 6.info:eu-repo/semantics/publishedVersio
Chemical sensors based on polymer composites with carbon nanotubes and graphene: the role of the polymer
Inclusive and multiplicity dependent production of electrons from heavy-flavour hadron decays in pp and p-Pb collisions
Measurements of the production of electrons from heavy-flavour hadron decays in pp collisions at root s = 13 TeV at midrapidity with the ALICE detector are presented down to a transverse momentum (p(T)) of 0.2 GeV/c and up to p(T) = 35 GeV/c, which is the largest momentum range probed for inclusive electron measurements in ALICE. In p-Pb collisions, the production cross section and the nuclear modification factor of electrons from heavy-flavour hadron decays are measured in the p(T) range 0.5 < p(T) < 26 GeV/c at root s(NN) = 8.16 TeV. The nuclear modification factor is found to be consistent with unity within the statistical and systematic uncertainties. In both collision systems, first measurements of the yields of electrons from heavy-flavour hadron decays in different multiplicity intervals normalised to the multiplicity-integrated yield (self-normalised yield) at midrapidity are reported as a function of the self-normalised charged-particle multiplicity estimated at midrapidity. The self-normalised yields in pp and p-Pb collisions grow faster than linear with the self-normalised multiplicity. A strong p(T) dependence is observed in pp collisions, where the yield of high-p(T) electrons increases faster as a function of multiplicity than the one of low-p(T) electrons. The measurement in p-Pb collisions shows no p(T) dependence within uncertainties. The self-normalised yields in pp and p-Pb collisions are compared with measurements of other heavy-flavour, light-flavour, and strange particles, and with Monte Carlo simulations
First measurement of the |t|-dependence of coherent J/Ï photonuclear production
The first measurement of the cross section for coherent J/Ï photoproduction as a function of |t|, the square of the momentum transferred between the incoming and outgoing target nucleus, is presented. The data were measured with the ALICE detector in ultra-peripheral PbâPb collisions at a centre-of-mass energy per nucleon pair sNN=5.02TeV with the J/Ï produced in the central rapidity region |y|<0.8, which corresponds to the small Bjorken-x range (0.3â1.4)Ă10â3.
The measured |t|-dependence is not described by computations based only on the Pb nuclear form factor, while the photonuclear cross section is better reproduced by models including shadowing according to the leading-twist approximation, or gluon-saturation effects from the impact-parameter dependent BalitskyâKovchegov equation. These new results are therefore a valid tool to constrain the relevant model parameters and to investigate the transverse gluonic structure at very low Bjorken-x.publishedVersio
First measurement of coherent Ï0 photoproduction in ultra-peripheral XeâXe collisions at âsNN = 5.44 TeV
The first measurement of the coherent photoproduction of Ï0 vector mesons in ultra-peripheral XeâXe collisions at sNN=5.44 TeV is presented. This result, together with previous HERA Îłp data and ÎłâPb measurements from ALICE, describes the atomic number (A) dependence of this process, which is particularly sensitive to nuclear shadowing effects and to the approach to the black-disc limit of QCD at a semi-hard scale. The cross section of the Xe+XeâÏ0+Xe+Xe process, measured at midrapidity through the decay channel Ï0âÏ+Ïâ, is found to be dÏ/dy=131.5±5.6(stat.)â16.9+17.5(syst.) mb. The ratio of the continuum to resonant contributions for the production of pion pairs is also measured. In addition, the fraction of events accompanied by electromagnetic dissociation of either one or both colliding nuclei is reported. The dependence on A of cross section for the coherent Ï0 photoproduction at a centre-of-mass energy per nucleon of the ÎłA system of WÎłA,n=65 GeV is found to be consistent with a power-law behaviour Ï(ÎłAâÏ0A)âAα with a slope α=0.96±0.02(syst.). This slope signals important shadowing effects, but it is still far from the behaviour expected in the black-disc limit.publishedVersio
Hypertriton Production in p-Pb Collisions at âsNN = 5.02 TeV
The study of nuclei and antinuclei production has proven to be a powerful
tool to investigate the formation mechanism of loosely bound states in
high-energy hadronic collisions. The first measurement of the production of
in p-Pb collisions at = 5.02
TeV is presented in this Letter. Its production yield measured in the rapidity
interval -1 < y < 0 for the 40% highest multiplicity p-Pb collisions is . The measurement is compared with the expectations of statistical
hadronisation and coalescence models, which describe the nucleosynthesis in
hadronic collisions. These two models predict very different yields of the
hypertriton in small collision systems such as p-Pb and therefore the
measurement of is crucial to distinguish between them.
The precision of this measurement leads to the exclusion with a significance
larger than 6 of some configurations of the statistical hadronisation,
thus constraining the production mechanism of loosely bound states
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