159 research outputs found
Alternative mRNA Editing in Trypanosomes Is Extensive and May Contribute to Mitochondrial Protein Diversity
- Author
- B Liu
- CJ Decker
- DJ Koslowsky
- DJ Koslowsky
- EO Ogbadoyi
- GR Riley
- J Edqvist
- J Fang
- J Lukes
- JE Feagin
- JL Kabat
- JM Abraham
- KD Stuart
- KJ Chang
- KR Matthews
- L Simpson
- LF Landweber
- LK Read
- M Chaudhuri
- Michael Cipriano
- Michael Gray
- NR Sturm
- P Rice
- R Benne
- RA Corell
- S Madison-Antenucci
- S Stamm
- SM Aldritt
- Stephen L. Hajduk
- T Maniatis
- T Ochsenreiter
- T Ochsenreiter
- T Ochsenreiter
- Torsten Ochsenreiter
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2007
- Field of study
The editing of trypanosome mitochondrial mRNAs produces transcripts necessary for mitochondrial functions including electron transport and oxidative phosphorylation. Precursor-mRNAs are often extensively edited by specific uridine insertion or deletion that is directed by small guide RNAs (gRNAs). Recently, it has been shown that cytochrome c oxidase subunit III (COXIII) mRNAs can be alternatively edited to encode a novel mitochondrial membrane protein composed of a unique hydrophilic N-terminal sequence of unknown function and the C-terminal hydrophobic segment of COXIII. To extend the analysis of alternative editing in Trypanosoma brucei we have constructed libraries with over 1100 full-length mitochondrial cDNAs and the sequences of over 1200 gRNA genes. Using this data, we show that alternative editing of COXIII, ATPase subunit 6 (A6), and NADH dehydrogenase subunits 7, 8 and 9 (ND7, 8, 9) mRNAs can produce novel open reading frames (ORFs). Several gRNAs potentially responsible for the alternative editing of these mRNAs were also identified. These findings show that alternative editing of mitochondrial mRNAs is common in T. brucei and expands the diversity of mitochondrial proteins in these organisms
Analysis of cell wall proteins regulated in stem of susceptible and resistant tomato species after inoculation with Ralstonia solanacearum: a proteomic approach
- Author
- Andreas Pich
- AR Park
- B Wilkinson
- BS Watson
- CH Foyer
- CM Nicolet
- CP Soh
- D Dahal
- Diwakar Dahal
- DJ Bradley
- DJ Cipriano
- DJ Cosgrove
- DL Jao
- E Jamet
- E Jamet
- F Brunner
- F Passardi
- GI Cassab
- H Harrak
- H Koiwa
- H Schagger
- Hans Peter Braun
- J Grenier
- J Raymond
- JC Pennycooke
- JE Thompson
- JI Ibeas
- K Lehto
- K Wydra
- Kerstin Wydra
- L Tang
- LF Brisson
- M Curto
- M Hopkins
- MH Hsieh
- MÁ Castillejo
- N Carpita
- N Entelis
- RA Dixon
- RS Chowdhuri
- S Echevarría-Zomeño
- S Yan
- SC Fry
- SD Copley
- SJ Lee
- TP Denny
- U Ryser
- V Neuhoff
- V Neuhoff
- VS Asirvatham
- WH Werhahn
- Z Minic
- Publication venue
- Springer Netherlands
- Publication date
- 01/01/2010
- Field of study
Proteomics approach was used to elucidate the molecular interactions taking place at the stem cell wall level when tomato species were inoculated with Ralstonia solanacearum, a causative agent of bacterial wilt. Cell wall proteins from both resistant and susceptible plants before and after the bacterial inoculation were extracted from purified cell wall with salt buffers and separated with 2-D IEF/SDS–PAGE and with 3-D IEF/SDS/SDS–PAGE for basic proteins. The gels stained with colloidal Coomassie revealed varied abundance of protein spots between two species (eight proteins in higher abundance in resistant and six other in susceptible). Moreover, proteins were regulated differentially in response to bacterial inoculation in resistant (seven proteins increased and eight other decreased) as well as in susceptible plants (five proteins elevated and eight other suppressed). Combination of MALDI-TOF/TOF MS and LC-ESI-IonTrap MS/MS lead to the identification of those proteins. Plants responded to pathogen inoculation by elevating the expression of pathogenesis related, other defense related and glycolytic proteins in both species. However, cell wall metabolic proteins in susceptible, and antioxidant, stress related as well as energy metabolism proteins in resistant lines were suppressed. Most of the proteins of the comparative analysis and other randomly picked spots were predicted to have secretion signals except some classical cytosolic proteins
Compressed representation of a partially defined integer function over multiple arguments
- Author
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdelalim AA
- Abdullin S
- Abdulsalam A
- Acosta D
- Acosta MV
- Adair A
- Adam W
- Adams MR
- Adams T
- Adiguzel A
- Adler V
- Adzic P
- Agram J-L
- Aguilar-Benitez M
- Ahmad M
- Ahmad WH
- Ahuja S
- Akchurin N
- Akgun B
- Akgun U
- Akin IV
- Alagoz E
- Albajar C
- Albayrak EA
- Albergo S
- Albrow M
- Alcaraz Maestre J
- Alda Junior WL
- Alderweireldt S
- Alexander J
- Aliev T
- Alimena J
- Almeida N
- Alverson G
- Alves GA
- Amapane N
- Amsler C
- Anagnostou G
- Anastassov A
- Anderson J
- Andrea J
- Andreev V
- Andreev V
- Andreev Y
- Andrews W
- Androsov K
- Antonelli L
- Antunovic Z
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- Apollinari G
- Appelt E
- Apresyan A
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- Arcidiacono R
- Arenton MW
- Arfaei H
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- Arneodo M
- Arora S
- Asavapibhop B
- Asawatangtrakuldee C
- Asghar MI
- Asin I
- Askew A
- Aslanoglou X
- Assran Y
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- Avetisyan A
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- Azhgirey I
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- Beirao Da Cruz E Silva C
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- Publication venue
- Publication date
- 01/01/2013
- Field of study
In OLAP (OnLine Analitical Processing) data are analysed in an n-dimensional cube. The cube may be represented as a partially defined function over n arguments. Considering that often the function is not defined everywhere, we ask: is there a known way of representing the function or the points in which it is defined, in a more compact manner than the trivial one
Construção e validação de vídeo educativo para orientação de pais de crianças em cateterismo intermitente limpo
- Author
- Alexandre NMC
- Alligood MR
- Andrade MR
- Barbosa DC
- Bruni DS
- Campos CVS
- Cipriano MAB
- Cogo ALP
- Cristiana Brasil de Almeida Rebouças
- De Jong TPVM
- Gomes LF
- Karino CA
- Lobiondo-Wood G
- Lynn MR
- Maria Aneuma Bastos Cipriano
- Maria Vera Lúcia Moreira Leitão Cardoso
- Marília Brito de Lima
- Masters K
- Moraes AF
- Nascimento LFC
- Ostherr K
- Pasquali L
- Paulo César de Almeida
- Pestana MH
- Polit DF
- Razera APR
- Roy C
- Régia Christina Moura Barbosa Castro
- Salvador PTC
- Teixeira MM
- Ulsenheimer MMM
- Zombini EV
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- 01/12/2017
- Field of study
RESUMO Objetivo: Construir e validar vídeo educativo para orientação de pais de crianças em cateterismo intermitente limpo. Método: Estudo metodológico, desenvolvido em duas etapas: construção e validação de vídeo com juízes expertises no período de março a dezembro de 2016. A construção da tecnologia teve como referencial teórico a Teoria de Adaptação. Para análise dos dados utilizou-se do índice de correlação intraclasse. Resultados: A primeira versão do vídeo foi composta por 12 minutos, a validação indicou a substituição de termos técnicos por linguagem coloquial, dinamismo nos diálogos e menção à lavagem das mãos antes de reunir o material. No que se refere à confiabilidade total, o coeficiente de correlação intraclasse para todas as categorias avaliadas obteve o valor de 0,768, considerado razoável. Na avaliação de clareza de linguagem, pertinência à prática e relevância teórica, os resultados foram 0,745, 0,771 e 0,777, respectivamente, considerados razoáveis, com p<0,0001. Conclusão: O vídeo educativo mostrou-se válido quanto à aparência e ao conteúdo, com potencial para mediar práticas educativas em contexto hospitalar e ambulatorial
Career perspective: Ralph F. Goldman—military ergonomics
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Observation of the diphoton decay of the Higgs boson and measurement of its properties
- Author
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullin S
- Abdulsalam A
- Acosta D
- Acosta JG
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- Publication venue
- Publication date
- 01/01/2014
- Field of study
Peer reviewe
Precise determination of the mass of the Higgs boson and tests of compatibility of its couplings with the standard model predictions using proton collisions at 7 and 8 TeV
- Author
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullin S
- Abdulsalam A
- Acosta D
- Acosta JG
- Adair A
- Adam W
- Adams JR
- Adams MR
- Adams T
- Adiguzel A
- Adler V
- Adzic P
- Afanasiev S
- Agapitos A
- Agram JL
- Ahmad A
- Ahmad M
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- Akin IV
- Albajar C
- Albayrak EA
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- Albrow M
- Alcaraz Maestre J
- Aldaya Martin M
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- Alexander J
- Alimena J
- Alverson G
- Alves GA
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- Amsler C
- Anagnostou G
- Anderson I
- Anderson J
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- Bagliesi G
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- Banerjee S
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- Publication venue
- Publication date
- 01/01/2014
- Field of study
Peer reviewe
Study of double parton scattering using W+2-jet events in proton-proton collisions at √s=7 TeV
- Author
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdelalim AA
- Abdullin S
- Abdulsalam A
- Acosta D
- Acosta JG
- Acosta MV
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- Publication venue
- Publication date
- 01/01/2013
- Field of study
Peer reviewe
Search for new physics in the multijet and missing transverse momentum final state in proton-proton collisions at √s=8 Tev
- Author
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdelalim AA
- Abdullin S
- Abdulsalam A
- Acosta D
- Acosta JG
- Acosta MV
- Adair A
- Adam W
- Adams MR
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- Publication venue
- Publication date
- 01/01/2014
- Field of study
Peer reviewe
Search for Dark Matter and Supersymmetry with a Compressed Mass Spectrum in the Vector Boson Fusion Topology in Proton-Proton Collisions at root s=8 TeV
- Author
- Aarrestad TK
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullin S
- Abdulsalam A
- Abu Zeid S
- Ackert A
- Acosta D
- Acosta JG
- Adair A
- Adam W
- Adams JR
- Adams MR
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- Adiguzel A
- Adzic P
- Agapitos A
- Aggleton R
- Agram J-L
- Ahmad A
- Ahmad M
- Ahmad M
- Ahmed I
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- Akchurin N
- Akgun B
- Al-bataineh A
- Albergo S
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- Alcaraz Maestre J
- Aldaya Martin M
- Alderweireldt S
- Aldá Júnior WL
- Aleksandrov A
- Alexander J
- Alimena J
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- Alunni Solestizi L
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- Anagnostou G
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- Andreev Yu
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- Wang R-J
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- Wang TW
- Wang Y
- Wang Z
- Wang Z
- Waqas M
- Wardle N
- Wasserbaech S
- Wayand S
- Wayne M
- Weber H
- Weber HA
- Weber M
- Weber M
- Wei H
- Weiler T
- Weinberg M
- Welke C
- Wendland L
- Weng Y
- Wertz S
- West C
- Wetzel J
- Whitbeck A
- Wickramage N
- Wilbur S
- Williams T
- Williamson S
- Wimpenny S
- Winer BL
- Winn D
- Wissing C
- Wittich P
- Wolf M
- Wolf R
- Wolfe E
- Wood D
- Wood J
- Woodard A
- Woods N
- Wright D
- Wu Z
- Wulsin HW
- Wulz C-E
- Wyslouch B
- Wöhrmann C
- Würthwein F
- Xia F
- Xiao M
- Xie S
- Xie W
- Xin Y
- Xu L
- Xu Q
- Xu Z
- Yagil A
- Yalvac M
- Yang M
- Yang UK
- Yang Y
- Yang YC
- Yates BR
- Yazgan E
- Yelton J
- Yetkin EA
- Yetkin T
- Yi K
- Yilmaz Y
- Yohay R
- Yonamine R
- Yoo HD
- Yoo J
- You C
- Yu GB
- Yu I
- Yu SS
- Yumiceva F
- Yusli MN
- Zabel J
- Zabi A
- Zaganidis N
- Zagozdzinska A
- Zakaria M
- Zalewski P
- Zanetti A
- Zanetti M
- Zarubin A
- Zeinali M
- Zenoni F
- Zenz SC
- Zeuner WD
- Zevi Della Porta G
- Zeyrek M
- Zghiche A
- Zhang F
- Zhang H
- Zhang J
- Zhao J
- Zhokin A
- Zhu RY
- Zhukov V
- Zhukova V
- Zolkapli Z
- Zorbilmez C
- Zotto P
- Zou D
- Zsigmond AJ
- Zucchetta A
- Zumerle G
- Zuranski A
- Publication venue
- Publication date
- 01/01/2016
- Field of study
Peer reviewe
- …