Fragility functions for a reinforced concrete structure subjected to earthquake and tsunami in sequence

Many coastal regions lying on subduction zones are likely to experience the catastrophic effects of cascading earthquake and tsunami observed in recent events, e.g., 2011 Tohoku Earthquake and Tsunami. The influence of earthquake on the response of the structure to tsunami is difficult to quantify through damage observations from past events, since they only provide information on the combined effects of both perils. Hence, the use of analytical methodologies is fundamental. This paper investigates the response of a reinforced concrete frame subjected to realistic ground motion and tsunami inundation time histories that have been simulated considering a seismic source representative of the M9 2011 Tohoku earthquake event. The structure is analysed via nonlinear time-history analyses under (a) tsunami inundation only and (b) earthquake ground motion and tsunami inundation in sequence. Comparison of these analyses shows that there is a small impact of the preceding earthquake ground shaking on the tsunami fragility. The fragility curves constructed for the cascading hazards show less than 15% reduction in the median estimate of tsunami capacity compared to the fragility functions for tsunami only. This outcome reflects the fundamentally different response of the structure to the two perils: while the ground motion response of the structure is governed by its strength, ductility and stiffness, the tsunami performance of the structure is dominated by its strength. It is found that the ground shaking influences the tsunami displacement response of the considered structure due to the stiffness degradation induced in the ground motion cyclic response, but this effect decreases with increasing tsunami force

The ``Outside-In'' Outburst of HT Cassiopeiae

We present results from photometric observations of the dwarf nova system HT Cas during the eruption of November 1995. The data include the first two--colour observations of an eclipse on the rise to outburst. They show that during the rise to outburst the disc deviates significantly from steady state models, but the inclusion of an inner-disc truncation radius of about 4 $R_{wd}$ and a ``flared'' disc of semi-opening angle of $10^{\circ}$ produces acceptable fits. The disc is found to have expanded at the start of the outburst to about $0.41R_{L1}$, as compared to quiescent measurements. The accretion disc then gradually decreases in radius reaching $<0.32R_{L1}$ during the last stages of the eruption. Quiescent eclipses were also observed prior to and after the eruption and a revised ephemeris is calculated.Comment: 9 pages, 11 figures, to appear in MNRA

An Irradiation Effect in Nova DN Gem 1912 and the Significance of the Period Gap for Classical Novae

Continuous CCD photometry of the classical nova DN Gem during 52 nights in the years 1992-98 reveals a modulation with a period 0.127844 d. The semi-amplitude is about 0.03 mag. The stability of the variation suggests that it is the orbital period of the binary system. This interpretation makes DN Gem the fourth nova inside the cataclysmic variable (CV) period gap, as defined by Diaz and Bruch (1997), and it bolsters the idea that there is no period gap for classical novae. However, the number of known nova periods is still too small to establish this idea statistically. We eliminate several possible mechanisms for the variation, and propose that the modulation is driven by an irradiation effect. We find that model light curves of an irradiated secondary star, fit the data well. The inclination angle of the system is restricted by this model to 10 deg < i < 65 deg. We also refine a previous estimate of the distance to the binary system, and find d=1.6+/-0.6 kpc.Comment: 7 pages, Latex file, 2 .ps files and 3 .eps files. accepted for publication in MNRAS. also available at: ftp://ftp.astro.keele.ac.uk/pub/preprints/preprints.htm

Pharmacological screening using an FXN-EGFP cellular genomic reporter assay for the therapy of Friedreich ataxia

Copyright @ 2013 Li et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.Friedreich ataxia (FRDA) is an autosomal recessive disorder characterized by neurodegeneration and cardiomyopathy. The presence of a GAA trinucleotide repeat expansion in the first intron of the FXN gene results in the inhibition of gene expression and an insufficiency of the mitochondrial protein frataxin. There is a correlation between expansion length, the amount of residual frataxin and the severity of disease. As the coding sequence is unaltered, pharmacological up-regulation of FXN expression may restore frataxin to therapeutic levels. To facilitate screening of compounds that modulate FXN expression in a physiologically relevant manner, we established a cellular genomic reporter assay consisting of a stable human cell line containing an FXN-EGFP fusion construct, in which the EGFP gene is fused in-frame with the entire normal human FXN gene present on a BAC clone. The cell line was used to establish a fluorometric cellular assay for use in high throughput screening (HTS) procedures. A small chemical library containing FDA-approved compounds and natural extracts was screened and analyzed. Compound hits identified by HTS were further evaluated by flow cytometry in the cellular genomic reporter assay. The effects on FXN mRNA and frataxin protein levels were measured in lymphoblast and fibroblast cell lines derived from individuals with FRDA and in a humanized GAA repeat expansion mouse model of FRDA. Compounds that were established to increase FXN gene expression and frataxin levels included several anti-cancer agents, the iron-chelator deferiprone and the phytoalexin resveratrol.Muscular Dystrophy Association (USA), the National Health and Medical Research Council (Australia), the Friedreich’s Ataxia Research Alliance (USA), the Brockhoff Foundation (Australia), the Friedreich Ataxia Research Association (Australasia), Seek A Miracle (USA) and the Victorian Government’s Operational Infrastructure Support Program

Model reference adaptive control of a nonsmooth dynamical system

In this paper a modified model reference adaptive control (MRAC) technique is presented which can be used to control systems with nonsmooth characteristics. Using unmodified MRAC on (noisy) nonsmooth systems leads to destabilization of the controller. A localized analysis is presented which shows that the mechanism behind this behavior is the presence of a time invariant zero eigenvalue in the system. The modified algorithm is designed to eliminate this zero eigenvalue, making all the system eigenvalues stable. Both the modified and unmodified strategies are applied to an experimental system with a nonsmooth deadzone characteristic. As expected the unmodified algorithm cannot control the system, whereas the modified algorithm gives stable robust control, which has significantly improved performance over linear fixed gain control

Influence of fly ash blending on hydration and physical behavior of Belite-Alite-Ye'elimite cements

A cement powder, composed of belite, alite and ye’elimite, was blended with 0, 15 and 30 wt% of fly ash and the resulting lended cements were further characterized. During hydration, the presence of fly ash caused the partial inhibition of both AFt degradation and belite reactivity, even after 180 days. The compressive strength of the corresponding mortars increased by increasing the fly ash content (68, 73 and 82 MPa for mortars with 0, 15 and 30 wt% of fly ash, respectively, at 180 curing days), mainly due to the diminishing porosity and pore size values. Although pozzolanic reaction has not been directly proved there are indirect evidences.This work is part of the Ph.D. of D. Londono-Zuluaga funded by Beca Colciencias 646—Doctorado en el exterior and Enlaza Mundos 2013 program grant. Cement and Building materials group (CEMATCO) from National University of Colombia is acknowledged for providing the calorimetric measurements. Funding from Spanish MINECO BIA2017-82391-R and I3 (IEDI-2016-0079) grants, co-funded by FEDER, are acknowledged

Observation of associated near-side and away-side long-range correlations in √sNN=5.02 TeV proton-lead collisions with the ATLAS detector

Two-particle correlations in relative azimuthal angle (Δϕ) and pseudorapidity (Δη) are measured in √sNN=5.02  TeV p+Pb collisions using the ATLAS detector at the LHC. The measurements are performed using approximately 1  μb-1 of data as a function of transverse momentum (pT) and the transverse energy (ΣETPb) summed over 3.1<η<4.9 in the direction of the Pb beam. The correlation function, constructed from charged particles, exhibits a long-range (2<|Δη|<5) “near-side” (Δϕ∼0) correlation that grows rapidly with increasing ΣETPb. A long-range “away-side” (Δϕ∼π) correlation, obtained by subtracting the expected contributions from recoiling dijets and other sources estimated using events with small ΣETPb, is found to match the near-side correlation in magnitude, shape (in Δη and Δϕ) and ΣETPb dependence. The resultant Δϕ correlation is approximately symmetric about π/2, and is consistent with a dominant cos⁡2Δϕ modulation for all ΣETPb ranges and particle pT

Search for the neutral Higgs bosons of the minimal supersymmetric standard model in pp collisions at root s=7 TeV with the ATLAS detector

A search for neutral Higgs bosons of the Minimal Supersymmetric Standard Model (MSSM) is reported. The analysis is based on a sample of proton-proton collisions at a centre-of-mass energy of 7TeV recorded with the ATLAS detector at the Large Hadron Collider. The data were recorded in 2011 and correspond to an integrated luminosity of 4.7 fb-1 to 4.8 fb-1. Higgs boson decays into oppositely-charged muon or τ lepton pairs are considered for final states requiring either the presence or absence of b-jets. No statistically significant excess over the expected background is observed and exclusion limits at the 95% confidence level are derived. The exclusion limits are for the production cross-section of a generic neutral Higgs boson, φ, as a function of the Higgs boson mass and for h/A/H production in the MSSM as a function of the parameters mA and tan β in the mhmax scenario for mA in the range of 90GeV to 500 GeV. Copyright CERN

Measurement of the cross-section of high transverse momentum vector bosons reconstructed as single jets and studies of jet substructure in pp collisions at √s = 7 TeV with the ATLAS detector

This paper presents a measurement of the cross-section for high transverse momentum W and Z bosons produced in pp collisions and decaying to all-hadronic final states. The data used in the analysis were recorded by the ATLAS detector at the CERN Large Hadron Collider at a centre-of-mass energy of √s = 7 TeV;{\rm Te}{\rm V}$and correspond to an integrated luminosity of$4.6\;{\rm f}{{{\rm b}}^{-1}}$. The measurement is performed by reconstructing the boosted W or Z bosons in single jets. The reconstructed jet mass is used to identify the W and Z bosons, and a jet substructure method based on energy cluster information in the jet centre-of-mass frame is used to suppress the large multi-jet background. The cross-section for events with a hadronically decaying W or Z boson, with transverse momentum${{p}_{{\rm T}}}\gt 320\;{\rm Ge}{\rm V}$and pseudorapidity$|\eta |\lt 1.9$, is measured to be${{\sigma }_{W+Z}}=8.5\pm 1.7$ pb and is compared to next-to-leading-order calculations. The selected events are further used to study jet grooming techniques