60 research outputs found
Measurement of the inclusive and dijet cross-sections of b-jets in pp collisions at sqrt(s) = 7 TeV with the ATLAS detector
- Author
- Aad G
- Abbott B
- Abdallah J
- Abdelalim AA
- Abdesselam A
- Abdinov O
- Abi B
- Abolins M
- Abramowicz H
- Abreu H
- Acerbi E
- Acharya BS
- Ackers M
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- Adelman J
- Aderholz M
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- Aguilar-Saavedra JA
- Aharrouche M
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- Valladolid Gallego E
- Vallecorsa S
- Valls Ferrer JA
- van der Graaf H
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- van der Poel E
- van der Ster D
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- van Eldik N
- van Gemmeren P
- van Kesteren Z
- van Vulpen I
- Vandelli W
- Vandoni G
- Vaniachine A
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- Vannucci F
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- Varnes EW
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- Vartapetian A
- Varvell KE
- Vassilakopoulos VI
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- Vermeulen JC
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- Vichou I
- Vickey T
- Viegas FJTA
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- Villa M
- Villaplana Perez M
- Vilucchi E
- Vincter MG
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- Vives Vaque F
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- Vogel A
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- Volpini G
- von der Schmitt H
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- von Radziewski H
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- Vorobel V
- Vorobiev AP
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- Vos M
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- Vossebeld JH
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- Vuillermet R
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- Wagner W
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- Waller P
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- Weber MS
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- Weidberg AR
- Weingarten J
- Weiser C
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- Wells PS
- Wen M
- Wenaus T
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- Weng Z
- Wengler T
- Wenig S
- Wermes N
- Werner M
- Werner P
- Werth M
- Wessels M
- Whalen K
- Wheeler-Ellis SJ
- Whitaker SP
- White A
- White MJ
- White S
- Whitehead SR
- Whiteson D
- Whittington D
- Wicek F
- Wicke D
- Wickens FJ
- Wiedenmann W
- Wielers M
- Wienemann P
- Wiglesworth C
- Wiik LAM
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- Wildt MA
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- Wilkens HG
- Will JZ
- Williams E
- Williams HH
- Willis W
- Willocq S
- Wilson A
- Wilson JA
- Wilson MG
- Wingerter-Seez I
- Winkelmann S
- Winklmeier F
- Wittgen M
- Wolter MW
- Wolters H
- Wooden G
- Wosiek BK
- Wotschack J
- Woudstra MJ
- Wraight K
- Wright C
- Wrona B
- Wu SL
- Wu X
- Wu Y
- Wulf E
- Wunstorf R
- Wynne BM
- Xaplanteris L
- Xella S
- Xie S
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- Xu C
- Xu D
- Xu G
- Yabsley B
- Yagci KD
- Yamada M
- Yamamoto A
- Yamamoto K
- Yamamoto S
- Yamamura T
- Yamaoka J
- Yamazaki T
- Yamazaki Y
- Yan Z
- Yang H
- Yang S
- Yang UK
- Yang Y
- Yang Y
- Yang Z
- Yanush S
- Yao W-M
- Yao Y
- Yasu Y
- Ye J
- Ye S
- Yildiz HD
- Yilmaz M
- Yoosoofmiya R
- Yorita K
- Yoshida R
- Young C
- Youssef S
- Yu D
- Yu J
- Yu J
- Yuan L
- Yurkewicz A
- Zaets VG
- Zaidan R
- Zaitsev AM
- Zajacova Z
- Zalite YK
- Zanello L
- Zarzhitsky P
- Zaytsev A
- Zdrazil M
- Zeitnitz C
- Zeller M
- Zema PF
- Zemla A
- Zendler C
- Zenin AV
- Zenin O
- Zenis T
- Zenonos Z
- Zenz S
- Zerwas D
- Zhan Z
- Zhang D
- Zhang H
- Zhang J
- Zhang X
- Zhang Z
- Zhao L
- Zhao T
- Zhao Z
- Zhemchugov A
- Zheng S
- Zhong J
- Zhou B
- Zhou N
- Zhou Y
- Zhu CG
- Zhu H
- Zhu Y
- Zhuang X
- Zhuravlov V
- Zieminska D
- Zilka B
- Zimmermann R
- Zimmermann S
- Zimmermann S
- Ziolkowski M
- Zitoun R
- Zivkovic L
- Zmouchko VV
- Zobernig G
- Zoccoli A
- Zolnierowski Y
- Zsenei A
- zur Nedden M
- Zutshi V
- Zwalinski L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 31/12/2010
- Field of study
The inclusive and dijet production cross-sections have been measured for jets
containing b-hadrons (b-jets) in proton-proton collisions at a centre-of-mass
energy of sqrt(s) = 7 TeV, using the ATLAS detector at the LHC. The
measurements use data corresponding to an integrated luminosity of 34 pb^-1.
The b-jets are identified using either a lifetime-based method, where secondary
decay vertices of b-hadrons in jets are reconstructed using information from
the tracking detectors, or a muon-based method where the presence of a muon is
used to identify semileptonic decays of b-hadrons inside jets. The inclusive
b-jet cross-section is measured as a function of transverse momentum in the
range 20 < pT < 400 GeV and rapidity in the range |y| < 2.1. The bbbar-dijet
cross-section is measured as a function of the dijet invariant mass in the
range 110 < m_jj < 760 GeV, the azimuthal angle difference between the two jets
and the angular variable chi in two dijet mass regions. The results are
compared with next-to-leading-order QCD predictions. Good agreement is observed
between the measured cross-sections and the predictions obtained using POWHEG +
Pythia. MC@NLO + Herwig shows good agreement with the measured bbbar-dijet
cross-section. However, it does not reproduce the measured inclusive
cross-section well, particularly for central b-jets with large transverse
momenta.Comment: 10 pages plus author list (21 pages total), 8 figures, 1 table, final
version published in European Physical Journal
Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008
- Author
- A Bidani
- A Bufalari
- A Djillali
- A El-Nawawy
- A Esteban
- A Esteban
- A Evans
- A Kortgen
- A Kumar
- A Liberati
- A O'Brien
- A Pesenti
- A Quartin
- AB Nathens
- AD Brook
- AD Oxman
- AF Connors Jr
- AF Shorr
- AG Pittas
- AG Turpie
- AJ Pollard
- American Society of Anaesthesiologists Task Force on Blood Component Therapy
- American Thoracic Society
- AP Goldman
- AP Wheeler
- B Allolio
- B Gardlund
- B Goldstein
- B Jonghe De
- B Krafte-Jacobs
- B Levy
- B Misset
- B Regnier
- B. Taylor Thompson
- BA Shapiro
- BA Wills
- BE Kreger
- BL Warren
- BM Patel
- BP Markovitz
- BT Thompson
- C Guerin
- C Guerin
- C Martin
- C Martin
- C Richard
- C Ronco
- C Strange
- C Vinsonneau
- CA Lindsay
- CA Nieuwenhoven van
- Canadian Critical Care Trials Group and the Canadian Critical Care Society
- CF Pizarro
- Christian Brun-Buisson
- CJ Fernandes Jr
- CJ Friedman
- CJ Wiedermann
- CL Holmes
- CL Holmes
- CL Sprung
- CL Sprung
- CM Pierce
- CMJ Vandenbroucke-Grauls
- College of American Pathologists
- CS Bouman
- CS King
- CW Colwell Jr
- D Annane
- D Backer De
- D Backer De
- D Cook
- D Cook
- D Keh
- D Lacomis
- D LeDoux
- D Mathieu
- D Osman
- D Schuller
- DC Angus
- DE Uehlinger
- Derek C. Angus
- DJ Cook
- DJ Cook
- DJ Cook
- DJ Cooper
- DK Heyland
- DK Heyland
- DL Sackett
- DM Meyer
- DN Hager
- DP Schuster
- DR Hirsch
- DW Landry
- E Abraham
- E Cerda
- E Jonge De
- E Jonge De
- E Rivers
- ED Kleijn De
- ED Kleijn de
- EF Bommel van
- EH Ibrahim
- EJ Giamarellos-Bourboulis
- EV Faustino
- EW Ely
- EW Ely
- F Blot
- F Fraisse
- F Gauvin
- F Lauzier
- F Schortgen
- F Sebat
- FA Riordan
- FC Tenover
- FM Brunkhorst
- G Berghe van den
- G Bertolini
- G Ceneviva
- G den Berghe Van
- G Guyatt
- G Guyatt
- G Schierhout
- German Hip Arthroplasty Trial Group (GHAT)
- GR Bernard
- GRADE working group
- Graham Ramsay
- GS Martin
- GS Martin
- GU Meduri
- GW Amsden
- H Frankel
- H Halkin
- H Kierdorf
- H Schiffl
- HB Nguyen
- Herwig Gerlach
- HJ Schünemann
- HL Corwin
- HL Corwin
- HP Wiedemann
- HT Klessig
- I Cinel
- J Attia
- J Boldt
- J Briegel
- J Briegel
- J Garnacho-Montero
- J Kellum
- J Klastersky
- J Lacroix
- J Mancebo
- J Mier
- J Villar
- JA Carcillo
- JA Carcillo
- JA Foland
- JA Hazelzet
- JA Kellum
- JA Lorente
- Janice L. Zimmerman
- JC Hurley
- JC Stothert Jr
- JD Sandham
- JE Irazuzta
- Jean M. Carlet
- Jean-Francois Dhainaut
- Jean-Louis Vincent
- Jeffrey S. Vender
- JF Cade
- JH Hansen-Flaschen
- JH Nichols
- JJ Augustine
- JJ Belch
- JJ Marini
- JJ Marini
- JL Gooch
- JL Moran
- JL Vincent
- JL Vincent
- JM Hammond
- JM Hyatt
- JM Kahn
- JMJ Hammond
- John J. Marini
- John Marshall
- Jonathan Sevransky
- JP Kress
- JP Kress
- JP Mitchell
- JR Curtis
- JR Curtis
- JS Gregory
- JS Krinsley
- JS Krinsley
- Julian Bion
- JW Devlin
- K Bendjelid
- K Bendjelid
- K Kruczinski
- K Reinhart
- KC Meyer
- KG Hickling
- Konrad Reinhart
- KP Steinberg
- KR Powell
- L Brochard
- L Brochard
- L Cronin
- L Gattinoni
- L Gattinoni
- L Gattinoni
- L Gattinoni
- L Gattinoni
- L Leibovici
- L Silvestri
- L Silvestri
- L Silvestri
- LA Mermel
- LB Ware
- M Antonelli
- M Buwalda
- M Chaïbou
- M Confalonieri
- M den Brinker
- M Egi
- M Ferrer
- M Kollef
- M Morrell
- M Oppert
- M Paul
- M Reincke
- M Tonelli
- M Varpula
- M Wilson
- MA Cal de la
- MA Hayes
- Marco Ranieri
- Margaret M. Parker
- Maurene Harvey
- MB Amato
- MB Amato
- MB Drakulovic
- MB Malay
- MF Jimenez
- MH Kollef
- MH Poleski
- MI Rudis
- Mitchell M. Levy
- MJ Levy
- MJ Murray
- MJ Tobin
- ML Malbrain
- MM Levy
- MM Levy
- MM Samama
- MP Weinstein
- MR Pinsky
- MR Shah
- MW Dunser
- MW Dunser
- MZ Ali
- N Basso
- N Safdar
- N Safdar
- ND Ferguson
- NI Shapiro
- NM Dung
- NP Day
- NP O'Grady
- NP O'Grady
- NT Ngo
- O Agu
- O Yildiz
- OI Abdel-Wahab
- P Barton
- P Jolliet
- P Saudan
- PC Cam
- PC Hebert
- PE Bollaert
- PE Bollaert
- PE Marik
- PG Pappas
- PQ Eichacker
- PR Hastings
- PTL Choi
- R Bellomo
- R Bellomo
- R Bellomo
- R Booy
- R D'Amico
- R Dahan
- R Hatala
- R MacLaren
- R Redman
- R Stocker
- R. Phillip Dellinger
- RC Bone
- RC Bone
- RC Freebairn
- RG Branco
- RG Brower
- RH Bartlett
- RH Kallet
- Richard Beale
- RK Kanter
- RL Mehta
- RL Moss
- Roman Jaeschke
- RP Dellinger
- RP Dellinger
- RP Dellinger
- RS Bresalier
- RS Watson
- S Finfer
- S Harvey
- S John
- S Kanji
- S Kanji
- S Magder
- S Masutani
- S Nadel
- S Ranjit
- S Trzeciak
- S Trzeciak
- Sean Townsend
- Selective Decontamination of the Digestive Tract Trialists' Collaborative Group
- SJ Finney
- SJ Mackenzie
- SK Pingleton
- SM Hollenberg
- SR Keeley
- ST Micek
- SX Zhou
- T Al-Kharrat
- T Sharshar
- T Weber
- T Yamazaki
- TE Stewart
- The Acute Respiratory Distress Syndrome Network
- The National Heart Lung, and Blood Institute ARDS Clinical Trials Network
- The Veterans Administration Systemic Sepsis Cooperative Study Group
- Thierry Calandra
- TJ Iberti
- TJ Parke
- UK Misra
- V Gasparovic
- VW Vanek
- VY Dombrovskiy
- W Geerts
- W Mauritz
- WH Geerts
- WH Marx
- WJ Lamm
- WJ Sibbald
- WR McCabe
- WT Linde-Zwirble
- Y Kupfer
- Y Sakr
- Y Tulzo Le
- YY Han
- Publication venue
- Springer-Verlag
- Publication date
- 01/01/2007
- Field of study
SCOPUS: ar.jinfo:eu-repo/semantics/publishe
The Early Data Release of the Dark Energy Spectroscopic Instrument
- Author
- Adame AG
- Aguilar J
- Ahlen S
- Alam S
- Aldering G
- Alexander DM
- Alfarsy R
- Allende Prieto C
- Alvarez M
- Alves O
- Anand A
- Andrade-Oliveira F
- Armengaud E
- Asorey J
- Avila S
- Aviles A
- Bailey S
- Balaguera-Antolinez A
- Ballester O
- Baltay C
- Bault A
- Bautista J
- Behera J
- Beltran SF
- BenZvi S
- Beraldo e Silva L
- Bermejo-Climent JR
- Berti A
- Besuner R
- Beutler F
- Bianchi D
- Blake C
- Blum R
- Bolton AS
- Brieden S
- Brodzeller A
- Brooks D
- Brown Z
- Buckley-Geer E
- Burtin E
- Cabayol-Garcia L
- Cai Z
- Canning R
- Cardiel-Sas L
- Carnero Rosell A
- Castander FJ
- Cervantes-Cota JL
- Chabanier S
- Chaussidon E
- Chaves-Montero J
- Chen S
- Chen X
- Chuang C
- Claybaugh T
- Cole S
- Cooper AP
- Cuceu A
- Davis TM
- Dawson K
- de Belsunce R
- de la Cruz R
- de la Macorra A
- de Mattia A
- Della Costa J
- Demina R
- Demirbozan U
- DeRose J
- Dey A
- Dey B
- Dhungana G
- Ding J
- Ding Z
- Doel P
- Doshi R
- Douglass K
- Edge A
- Eftekharzadeh S
- Eisenstein DJ
- Elliott A
- Ereza J
- Escoffier S
- Fagrelius P
- Fan X
- Fanning K
- Fawcett VA
- Ferraro S
- Flaugher B
- Font-Ribera A
- Forero-Romero JE
- Forero-Sanchez D
- Frenk CS
- Gansicke BT
- Garcia LA
- Garcia-Bellido J
- Garcia-Quintero C
- Garrison LH
- Gil-Marin H
- Golden-Marx J
- Gontcho Gontcho SA
- Gonzalez-Morales AX
- Gonzalez-Perez V
- Gordon C
- Graur O
- Green D
- Gruen D
- Guy J
- Hadzhiyska B
- Hahn C
- Han JJ
- Hanif MMS
- Herrera-Alcantar HK
- Honscheid K
- Hou J
- Howlett C
- Huterer D
- Irsic V
- Ishak M
- Jacques A
- Jana A
- Jiang L
- Jimenez J
- Jing YP
- Joudaki S
- Joyce R
- Jullo E
- Juneau S
- Karacayli NG
- Karim T
- Kehoe R
- Kent S
- Khederlarian A
- Kim S
- Kirkby D
- Kisner T
- Kitaura F
- Kizhuprakkat N
- Kneib J
- Koposov SE
- Kovacs A
- Kremin A
- Krolewski A
- L'Huillier B
- Lahav O
- Lambert A
- Lamman C
- Lan T-W
- Landriau M
- Lang D
- Lange JU
- Lasker J
- Le Guillou L
- Leauthaud A
- Levi ME
- Li TS
- Linder E
- Lyons A
- Magneville C
- Manera M
- Manser CJ
- Margala D
- Martini P
- McDonald P
- Medina GE
- Medina-Varela L
- Meisner A
- Mena-Fernandez J
- Meneses-Rizo J
- Mezcua M
- Miquel R
- Montero-Camacho P
- Moon J
- Moore S
- Moustakas J
- Mueller E
- Mundet J
- Munoz-Gutierrez A
- Myers AD
- Nadathur S
- Napolitano L
- Neveux R
- Newman JA
- Nie J
- Nikutta R
- Niz G
- Norberg P
- Noriega HE
- Paillas E
- Palanque-Delabrouille N
- Palmese A
- Pan Z
- Parkinson D
- Penmetsa S
- Percival WJ
- Perez-Fernandez A
- Perez-Rafols I
- Pieri M
- Poppett C
- Porredon A
- Pothier S
- Prada F
- Pucha R
- Raichoor A
- Ramirez-Perez C
- Ramirez-Solano S
- Rashkovetskyi M
- Ravoux C
- Rocher A
- Rockosi C
- Ross AJ
- Rossi G
- Ruggeri R
- Ruhlmann-Kleider V
- Sabiu CG
- Said K
- Saintonge A
- Samushia L
- Sanchez E
- Saulder C
- Schaan E
- Schlafly EF
- Schlegel D
- Scholte D
- Schubnell M
- Seo H
- Shafieloo A
- Sharples R
- Sheu W
- Silber J
- Sinigaglia F
- Siudek M
- Slepian Z
- Smith A
- Soumagnac MT
- Sprayberry D
- Stephey L
- Suarez-Perez J
- Sun Z
- Tan T
- Tarle G
- Tojeiro R
- Urena-Lopez LA
- Vaisakh R
- Valcin D
- Valdes F
- Valluri M
- Vargas-Magana M
- Variu A
- Verde L
- Walther M
- Wang B
- Wang MS
- Weaver BA
- Weaverdyck N
- Wechsler RH
- White M
- Xie Y
- Yang J
- Yeche C
- Yu J
- Yuan S
- Zhang H
- Zhang Z
- Zhao C
- Zheng Z
- Zhou R
- Zhou Z
- Zou H
- Zou S
- Zu Y
- Publication venue
- 'American Astronomical Society'
- Publication date
- 01/08/2024
- Field of study
\ua9 2024. The Author(s). Published by the American Astronomical Society. The Dark Energy Spectroscopic Instrument (DESI) completed its 5 month Survey Validation in 2021 May. Spectra of stellar and extragalactic targets from Survey Validation constitute the first major data sample from the DESI survey. This paper describes the public release of those spectra, the catalogs of derived properties, and the intermediate data products. In total, the public release includes good-quality spectral information from 466,447 objects targeted as part of the Milky Way Survey, 428,758 as part of the Bright Galaxy Survey, 227,318 as part of the Luminous Red Galaxy sample, 437,664 as part of the Emission Line Galaxy sample, and 76,079 as part of the Quasar sample. In addition, the release includes spectral information from 137,148 objects that expand the scope beyond the primary samples as part of a series of secondary programs. Here, we describe the spectral data, data quality, data products, Large-Scale Structure science catalogs, access to the data, and references that provide relevant background to using these spectra
Biased-corrected richness estimates for the Amazonian tree flora
- Author
- Ahuite Reategui MA
- Albuquerque BW
- Alexiades MN
- Alonso A
- Amaral IL
- Andrade A
- Araujo-Murakami A
- Arroyo L
- Assis RL
- Aymard C. GA
- Baider C
- Baker TR
- Balslev H
- Baraloto C
- Barbosa EM
- Barbosa FR
- Barlow J
- Berenguer E
- Brienen R
- Bánki OS
- Camargo JL
- Cano A
- Carrero Márquez YA
- Carvalho FA
- Casas LF
- Castaño Arboleda N
- Castellanos H
- Castilho CV
- Casula KR
- Cerón C
- Chave J
- Cintra BBL
- Comiskey JA
- Cornejo Valverde F
- Correa DF
- Costa FRC
- Costa JBP
- Cárdenas López D
- Cárdenas S
- da Silva Guimarães JR
- Dallmeier F
- Daly D
- Damasco G
- de Aguiar DPP
- de Andrade Lima Filho D
- de Andrade Miranda IP
- de Jesus Rodrigues D
- de Jesus Veiga Carim M
- de Leão Novo EMM
- de Lima RAF
- de Matos Bonates LC
- de Medeiros MB
- de Oliveira EA
- de Queiroz HL
- de Sousa Farias E
- de Souza Coelho L
- de Souza FC
- de Sá Carpanedo R
- de Toledo JJ
- Demarchi LO
- Dexter KG
- Di Fiore A
- Dionízia de Almeida Matos F
- do Amaral DD
- Doza HPD
- Draper F
- Duivenvoorden JF
- Duque A
- Dávila N
- Engel J
- Farfan-Rios W
- Farfan-Rios W
- Feeley KJ
- Feitosa YO
- Feldpausch TR
- Ferreira C
- Ferreira J
- Ferreira LV
- Fine PVA
- Flores BM
- Fonty É
- Fuentes A
- Galbraith D
- Gamarra LV
- Garcia-Cabrera K
- García-Villacorta R
- Gomes VHF
- Gonzales GPG
- Gonzales T
- Gribel R
- Guedes MC
- Guevara JE
- Gómez RZ
- Henkel TW
- Hernandez L
- Hilário RR
- Hoffman B
- Holmgren M
- Honorio Coronado EN
- Huamantupa-Chuquimaco I
- Irume MV
- Jimenez EM
- Junqueira AB
- Kalamandeen M
- Killeen TJ
- Klitgaard B
- Laurance SGW
- Laurance WF
- Levesley A
- Licona JC
- Linares-Palomino R
- Lloyd J
- Lopes A
- Lopes MA
- Lozada JR
- Luize BG
- Maas P
- Magalhães JLL
- Magnusson WE
- Malhi Y
- Manzatto AG
- Marimon BS
- Marimon-Junior BH
- Melgaço K
- Mendoza C
- Mesones I
- Milliken W
- Mogollón HF
- Molino J-F
- Monteagudo Mendoza A
- Montero JC
- Mostacedo B
- Nascimento HEM
- Nascimento MT
- Neill D
- Noronha JC
- Núñez Vargas P
- Oliveira AA
- Palacios Cuenca W
- Pansini S
- Pansonato MP
- Paredes MR
- Pauletto D
- Pena JLM
- Pennington T
- Peres CA
- Petronelli P
- Peñuela Mora MC
- Phillips JF
- Phillips OL
- Pickavance G
- Piedade MTF
- Pinto LFM
- Pires Martins M
- Pitman NCA
- Pos E
- Prado PI
- Prieto A
- Quaresma A
- Ramirez Arevalo F
- Ramirez-Angulo H
- Ramos JF
- Reis NFC
- Revilla JDC
- Rincón LM
- Rivas-Torres G
- Rocha M
- Rudas A
- Ruschel AR
- Sabatier D
- Salomão RP
- Sampaio AF
- Schietti J
- Schöngart J
- Scudeller VV
- Sierra R
- Silman MR
- Silva N
- Silva TSF
- Silveira M
- Simon MF
- Sousa TR
- Stevenson PR
- Stropp J
- Tello JS
- ter Steege H
- Terborgh J
- Thomas R
- Tirado M
- Torres-Lezama A
- Umaña MN
- Urrego Giraldo LE
- Valderrama Sandoval EH
- van Andel TR
- van der Heijden G
- Vasquez R
- Vela CIA
- Venticinque EM
- Vicentini A
- Vieira ICG
- Vilanova Torre E
- Villa B
- Villarroel D
- von Hildebrand P
- Vos VA
- Vriesendorp C
- Wang O
- Wittmann F
- Young KR
- Zagt R
- Zartman CE
- Zent EL
- Zent S
- Publication venue
- Nature Research
- Publication date
- 01/01/2020
- Field of study
Amazonian forests are extraordinarily diverse, but the estimated species richness is very much debated. Here, we apply an ensemble of parametric estimators and a novel technique that includes conspecific spatial aggregation to an extended database of forest plots with up-to-date taxonomy. We show that the species abundance distribution of Amazonia is best approximated by a logseries with aggregated individuals, where aggregation increases with rarity. By averaging several methods to estimate total richness, we confirm that over 15,000 tree species are expected to occur in Amazonia. We also show that using ten times the number of plots would result in an increase to just ~50% of those 15,000 estimated species. To get a more complete sample of all tree species, rigorous field campaigns may be needed but the number of trees in Amazonia will remain an estimate for years to come
A922 Sequential measurement of 1 hour creatinine clearance (1-CRCL) in critically ill patients at risk of acute kidney injury (AKI)
- Author
- Abbott TE
- Abdallah RI
- Abdel-Aal IR
- Abdelmonem SA
- Abdo WF
- Abellan AN
- Abellán AN
- Abellán AN
- Abellán AN
- Abrams ST
- Ackerley C
- Acuña M
- Adda M
- Adhikari NK
- Adriano G
- Adrie C
- Affatato R
- Affatato R
- Afonso-Rivero D
- Agarossi A
- Agarwal LK
- Ageeva T
- Agrawal R
- Aguayo-DeHoyos E
- Aguilar AL
- Aguilar-Alonso E
- Aguilar-Alonso E
- Aguilar-Alonso E
- Aguirregabyria M
- Ahmadnia E
- Ahn C
- Ahn JY
- Ahn JY
- Ahn MY
- Ahn MY
- Aitken LM
- Akalaev R
- Akbarzadeh A
- Akcan-Arikan A
- Akhlagh SH
- Akhtar N
- AKI Research Group
- Akiduki N
- Akin S
- Akizuki N
- Akkoc T
- Ala-Kokko T
- Alanio A
- Albaiceta GM
- Albaladejo P
- Alberto F
- Albuisson E
- Alcala MA
- Alcázar L
- Aldabo-Pallas T
- Aldana NN
- Aldecoa C
- Alegría L
- Alejandro R
- Alejo GC
- Alejos RM
- Alexandrova E
- Algarte R
- Algarte R
- Algieri I
- Algora-Weber A
- Alhamdi Y
- Aliaga FA
- Aliberti S
- Alkan A
- Almudena PM
- Almudevar PM
- Almudevar PM
- Almudévar PM
- Altıntas ND
- Alvarez J
- Alves SC
- Alzola LM
- Amargianitakis V
- Amaro R
- Amato MB
- Ambler M
- Amerongen MP
- Amininejad T
- Amor LL
- Amorim V
- Anand RK
- Andersen LW
- Andersson S
- Andoh K
- Andrade AH
- Andrade AH
- Andrade AH
- Andrade G
- Andreis DT
- Andreis DT
- Annane D
- Antonelli M
- Antoniadou A
- Antonio C
- Antonucci E
- Antón DG
- Anzueto A
- Appiani F
- Aquevedo A
- Aragon C
- Araujo NJ
- Araujo VF
- ARIAM registry of adult cardiac surgery
- ARIAM-ANDALUCIA
- Arias CC
- Arias N
- Arias-Verdu MD
- Arias-Verdu MD
- Arias-Verdu MD
- Armaganidis A
- Arora MK
- Arora N
- Arrigo M
- Arslantas MK
- Artiguenave M
- Aslanian P
- Aspide R
- Asyralyyeva G
- Ataman S
- Ataman S
- Atchade E
- Atchade E
- Atchasiri S
- Athapattu P
- Atkins G
- Aublanc M
- Aublanc M
- Augustin P
- Augustin P
- Auquier P
- Avilés-Jurado FX
- Avramidis V
- Ayala LY
- Aydin M
- Azevedo JC
- Azevedo JR
- Aznar GP
- Babalis D
- Babini G
- Bachli EB
- Bader A
- Bader A
- Baena J
- Baidya DK
- Baikova VN
- Bakker J
- Balcázar LC
- Balcázar LC
- Baldassarri R
- Baldwin CE
- Balik M
- Ball I
- Ballin A
- Balsera B
- Banderas-Bravo ME
- Banderas-Bravo ME
- Bandert A
- Bangstad IL
- Baptista N
- Baquero JD
- Barbadillo S
- Barberet G
- Barberet G
- Barberet G
- Barbier J
- Barcenilla F
- Barea-Mendoza JA
- Barinas OD
- Baron AV
- Barrachina LG
- Barral M
- Basile-Filho A
- Bassi GL
- Bates D
- Battistini M
- Bauer M
- Bauer PR
- Baumstarck K
- Baumstarck K
- Bawin M
- Bazan N
- Bañeras J
- Beane A
- Beduneau G
- Beduneau G
- Beduneau G
- Beeharry SD
- Beerepoot M
- Begzjav T
- Beishuizen A
- Bell C
- Belletti A
- Bellissimo-Rodrigues F
- Belloli A
- Bellomo R
- Bellver BQ
- Belmonte R
- Ben-Hamouda N
- Bendel S
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- Bernal FF
- Berric A
- Berrutti D
- Berthelsen RE
- Bertini P
- Bertini P
- Berto MB
- Besevli SG
- Bestle MH
- Bettex D
- Bettex DA
- Beunders R
- Bhasin D
- Bhattal MK
- Bhide S
- Bianchi I
- Bianchi I
- Bianzina S
- Bianzina S
- Bianzina S
- Bishop J
- Bissenova N
- Bisso MC
- Blans MJ
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- Bloomer MJ
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- Blot S
- Blot S
- Boa F
- Bobi Q
- Bodingbauer M
- Bodí M
- Boer C
- Bogossian E
- Bonet S
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- Borges FK
- Bouadma L
- Boucekine M
- Bougouin W
- Bourenne J
- Boyd JG
- Boyd JG
- Bozbay S
- Bozza F
- Bradac O
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- Braschi A
- Brasseur A
- Brasseur A
- Brasseur A
- Braune S
- Brazzi L
- Breitkreutz R
- Brianti R
- Brioni M
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- Brochard L
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- Brody DL
- Brook R
- Brousseau C
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- Brusasco C
- Brusasco C
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- Cairus C
- Cakin O
- Caliskan K
- Calpe P
- Calvo CP
- Calvo SA
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- Cambronero JA
- Cameron C
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- CAPCRI Study
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- Cardellino S
- Cardenas CL
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- Cariou A
- Carlesso E
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- Carmona SA
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- Carratalá A
- Carreira MM
- Carrero-Gómez F
- Carreño ER
- Carreño R
- Carvalho JP
- Carvalho KV
- Casals XN
- Casals XN
- Cassina T
- Castañeda DP
- Castellana D
- Castellanos A
- Castellanos A
- Castillo-Lorente E
- Castillo-Lorente E
- Catalan M
- Catalán RM
- Catena E
- Catena E
- Cauwenberghs H
- Cavalcanti D
- Cavalheiro AM
- Cavalier E
- Cavicchi FZ
- Cavicchi FZ
- Cengiz M
- Ceriani R
- Cermelli S
- Cerović O
- Cha YS
- Chabanne R
- Chacon-Alves S
- Champigneulle B
- Champigneulle B
- Chan KC
- Chan KK
- Chan WS
- Chang CH
- Chang WY
- Chao A
- Chao A
- Chao AS
- Chao HC
- Chaouat M
- Charitidou E
- Charpentier C
- Charpentier J
- Charron C
- Chatelon J
- Chaudhari HK
- Chaussard M
- Chavanon O
- Chaves S
- Chelly J
- Chemam S
- Chen CM
- Chen CM
- Chen CW
- Chen CW
- Chen GQ
- Chen L
- Chen YS
- Chen YS
- Chen YS
- Cheng CC
- Cheng CC
- Cheng CC
- Cheng CC
- Cheng KC
- Cheng YJ
- Chernyshuk S
- Chevret S
- Chhor V
- Chiang CC
- Chiang CH
- Chiang CH
- Chiang CH
- Chiappa C
- Chiou KR
- Chiou KR
- Chiou KR
- Chiu LC
- Chiumello D
- Chiurazzi C
- Chiurazzi C
- Cho Y
- Cho YJ
- Cho YJ
- Choi JY
- Choi JY
- Choi KS
- Choi S
- Choi YJ
- Choi YY
- Chok L
- Cholkraisuwat J
- Cholley B
- Chondropoulos S
- Chou W
- Chouris I
- Chouvarda I
- Christopher KB
- Chrétien JM
- Chrétien JM
- Chrétien JM
- Chumaev A
- Chung CR
- Churchill K
- Chytas A
- Cinel I
- Cinnella G
- Citerio G
- Citerio G
- Clavel M
- Clemente EA
- Clermont G
- Cleyet M
- Cohen Y
- Colaprico A
- Colino L
- Collange O
- Colombo A
- Colombo A
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- Combes A
- Concha P
- Connolly B
- Constan A
- Constan A
- Constan A
- Conte V
- Conti G
- Conti G
- Contreras KM
- Contreras MR
- Cook DJ
- Coombs M
- Cordeiro CP
- Cordero M
- Cordolcini V
- Cordovilla-Guardia S
- Cordón J
- Corona A
- Corona A
- Corradi F
- Corradi F
- Corradi F
- Correa-Chamorro E
- Corte FD
- Cortes ML
- Corzo L
- Coss-Bu JA
- Coss-Bu JA
- Costa MI
- Costa RC
- Costa RC
- Costa RC
- Costanzo E
- Cotoia A
- Cottini SR
- Cottle D
- Cotton H
- Cotton H
- Courant P
- Cowan R
- Creagh-Brown B
- Cressoni M
- Creteur J
- Creteur J
- Creteur J
- Creteur J
- Creteur J
- Creteur J
- Creteur J
- Creteur J
- Crimella F
- Cron N
- Cuellar AI
- Cui N
- Cunha MM
- Curiel-Balsera E
- Curiel-Balsera E
- Curinga M
- Curtis A
- Cuthbertson BH
- Cutuli SL
- Câmara M
- D'Arsigny C
- da Silva SL
- da Silva VZ
- Daga-Ruiz D
- Dalhuisen A
- Dalorzo M
- Damas P
- Dambrosio M
- Damås JK
- Das Neves A
- David H
- Davis C
- Davis P
- Day A
- de Abreu MG
- De Backer A
- De Brito-Ashurst I
- De Cassai A
- De Freitas FF
- De Gasperi A
- de Hoyos EA
- De la Calle-Pedrosa N
- de la Fuente MV
- De La Fuente-Martos C
- De La Fuente-Martos C
- De La Rica AS
- De la Torre MA
- De Maglie M
- De Maglie M
- de Molina FJ
- De Morton N
- de Oca Sandoval MA
- De Pascale G
- De Rosa S
- De Sanctis F
- De Silva AP
- De Sousa I
- de Vera AP
- de Wilde W
- De Zani D
- Deblier I
- DeBrunnar R
- Del Arco A
- Del Moral OL
- Del Olmo R
- Del Rosario CG
- Del Sorbo L
- Delgado CP
- Delgado MJ
- Delgado-Amaya M
- Demirkiran O
- Demoule A
- Denehy L
- Der Kinderen EP
- Descotte E
- Deshpande K
- Desmard M
- Desmard M
- Deveugele M
- Deye N
- Di Bello F
- Di Giancamillo M
- Di Gravio V
- Di Gregorio A
- Di Mussi R
- Di Rosso R
- Diaz DD
- Diaz P
- Dilek M
- Dilly MP
- Dima E
- Dimitroulakis K
- Dimitrov BD
- Dimitrov BD
- Dimopoulou IK
- Dinh A
- Divatia JV
- Dixon J
- Doganci M
- Doglia JA
- Doherty P
- Dolset RA
- Dominguez JP
- Domínguez JP
- Donald CL
- Donnino M
- Doorduin J
- Dorent R
- Dos Reis Miranda D
- Dos Santos HP
- Dougall PC
- Doyle J
- Doyle J
- Drover J
- Duarte R
- Dubois EA
- Dubrawski A
- Dubó S
- Dudas G
- Dudoignon E
- Dumas F
- Dunthorne E
- Duran N
- Durand M
- Durovray JD
- Durrant J
- Duzgun M
- Díaz E
- Díaz JJ
- Díaz M
- Díaz PV
- Dünser MW
- E Silva ZC
- E YY
- Ebeling G
- Echeverri JE
- Echeverría JG
- Ediboglu O
- Ediboglu O
- Egea-Guerero JJ
- Egginton JS
- Egi M
- El Adawy AS
- El Hamid MA
- El Hossainy R
- El Sayed E
- El Sayed F
- El Sayed I
- El-Hamamsy M
- El-Keraie A
- Eladawy S
- Elbers PW
- Elgendy M
- Eliet J
- Emmanuel J
- Emmerich M
- Encina B
- Endacott R
- Endacott R
- Engelberts D
- ENVIN-HELICS Study Group
- Erb J
- Erdogan M
- Eroles AA
- Escalada SH
- Escalada SH
- Escoval A
- Escribá A
- Escórcio S
- Eslami S
- Espinasse F
- Espinel E
- Estagnasie P
- Esteban A
- Estella A
- Estenssoro E
- Evelein-Brugman S
- Facchin F
- Faivre V
- Fang M
- Fanzaghi P
- Farias P
- Faulds MC
- Fave G
- Feehan A
- Feijoo AM
- Feliot E
- Ferez MA
- Fernandes MJ
- Fernandes N
- Fernandez NG
- Fernandez R
- Fernandez-Zamora MD
- Fernández IF
- Fernández L
- Fernández MV
- Fernández PA
- Fernández-Barat L
- Fernández-Mondéjar E
- Fernández-Ortega JF
- Ferraz AB
- Ferrero-Calleja J
- Ferri F
- Ferry A
- Ferré A
- Ferrón FR
- Ferrón FR
- Fiks T
- Fiks T
- Fileković S
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- Filho CA
- Filho CA
- Filipe E
- FINNRESUSCI Study Group
- Fischer G
- Fleischmann E
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- Floccard B
- Flowers E
- Follin A
- Follin A
- Fong KY
- Fontaiña LP
- Fontana V
- Fontenot T
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- Forni L
- Forni LG
- Forni LG
- Forni LG
- Fournel E
- Fox B
- Franchi P
- Francioni JE
- Francioni JE
- Franco JF
- Frantzeskaki F
- Frantzeskaki F
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- Frat JP
- Frat JP
- Freile MT
- Frenzel T
- Frigeni B
- Frithiof R
- Fritz C
- FROG ICU Investigators
- Fromentin M
- Frontera PR
- Fuentes M
- Fumagalli F
- Fumagalli F
- Fumis RR
- Fushimi K
- Gabán-Díez Á
- Gadgil S
- Gaide-Chevronnay L
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- Gaizauskas E
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- Gallego-Corpa AI
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- Garcia IP
- Garcia M
- Garcia PK
- Garcia-Alvarez JM
- Garcia-Alvarez JM
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- García MF
- García-Martínez MV
- García-Olivares P
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- Gavrychenko D
- Gayat E
- Geantot MA
- Gemmell L
- Gemmell LK
- Genc D
- Genève C
- Georgopoulos D
- Geri G
- GETGAG Working Group
- GETGAG/SEMICYUC
- Ghabina S
- Ghazal S
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- Ghosh S
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- Giannopoulos A
- Giesinger RE
- Gigorro RG
- Gil EM
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- Gommers D
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- Gonzalez-Engroba R
- González AS
- González BS
- González JC
- González-Jiménez AI
- Gonçalves B
- Goodwin S
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- Gordon M
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- Gouveia J
- Gracia RM
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- Grossestreuer A
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- Gupta D
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- Hayakawa M
- Hayakawa M
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- Hernandis V
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- Herrera AN
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- Hravnak M
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- Jardim JJ
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- Jonas M
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- Jovaisa T
- JSEPTIC (Japanese Society of Education for Physicians and Trainees in Intensive Care) Clinical Trial Group
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- Kleinpell R
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- St George’s University of London
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- Álvarez JT
- Álvarez-Lerma F
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2016
- Field of study
Meeting abstrac
Spontaneous Breathing in Early Acute Respiratory Distress Syndrome: Insights From the Large Observational Study to UNderstand the Global Impact of Severe Acute Respiratory FailurE Study
- Author
- Abad RD
- Abe T
- Abroug F
- Adams JC
- Adamsson RO
- Adolfsson A
- Aguilar RZ
- Aguirre JS
- Aguirre-Bermeo H
- Aisa TM
- Aisiku I
- Ajetunmobi OO
- Aker M
- Akyol OO
- Al Dorzi HM
- Al Jabbary AS
- Albaiceta GM
- Albarrak MM
- Albiero D
- Alda RS
- Alejandro RV
- Alexander P
- Algaba Á
- Aliaga FA
- Alisasis AU
- Allan RM
- Allue RM
- Almekhlaf G
- Alonso JG
- Altaf W
- Alvarez AM
- Alvarez J
- Amin P
- Amir F
- Amor M
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- Andersen FH
- Andoh K
- Andruszkiewicz P
- Aneman A
- Antonelli MM
- Antônio ACP
- Aoki N
- Appelberg H
- Arabi Y
- Arabi YM
- Araujo AM
- Arizmendi A
- Arnal JM
- Artiga MJD
- Artigas A
- Ascoli A
- Au SM
- Avila LE
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- Bailey IM
- Bailey MB
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- Banner-Goodspeed VM
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- Beck O
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- Beegle SH
- Beitler JR
- Bellani G
- Bellani G.
- Beloncle F
- Ben Souissi A
- Benslama A
- Beraldo DO
- Berghe C
- Berkelmans F
- Besset SL
- Bettini LR
- Beuret P
- Bezzi MG
- Bhardwaj VK
- Bhowmick K
- Biehler J
- Bigot C
- Bihari S
- Biondi RS
- Biscione RR
- Bisso MC
- Black CS
- Blakeman TC
- Blanco J
- Bolon S
- Borello SA
- Borotto EE
- Botteri M
- Bouchoucha S
- Boukhazna M
- Bouw MJ
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- Brochard L.
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- Bugedo G
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- Bumbasirevic V
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- Béduneau G
- Camsooksai J
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- Ceylan I
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- Eugenio Luis PS
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- Gazenkampf AA
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- Ghazi M
- Gianinetto H
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- Girgin NK
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- Goldgran-Toledano D
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- Gomaa D
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- Gomes RM
- Gomez PE
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- Gonzalez DR
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- González-Salamanca Á
- Gonçalves CH
- Goodson JC
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- Guttormsen AB
- Guérin C
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- Hunt A
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- Iglesias Moles S
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- Imai H
- Imma VP
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- Jimenez AG
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- Judy C
- Jurado MT
- Kadaba V
- Kajtor I
- Kakar V
- Kalaitzis E
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- Kraßler J
- Krstevski A
- Kulkarni S
- Kumar A
- Kurahashi K
- Kusumoto K
- Laake JH
- Laake JH
- Labarca EF
- Laffey J
- Laffey J.
- Laffey JG
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- Lanspa MJ
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- Larsson A
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- Le Moal C
- Lebbinck H
- Lee J
- Leemann-Refondini C
- Lemiale V
- Lemus JS
- Leon Yoshido HH
- Li B
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- Liew KY
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- Ñamendys-Silva SA
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- Publication venue
- 'Ovid Technologies (Wolters Kluwer Health)'
- Publication date
- 01/01/2019
- Field of study
OBJECTIVES: To describe the characteristics and outcomes of patients with acute respiratory distress syndrome with or without spontaneous breathing and to investigate whether the effects of spontaneous breathing on outcome depend on acute respiratory distress syndrome severity. DESIGN: Planned secondary analysis of a prospective, observational, multicentre cohort study. SETTING: International sample of 459 ICUs from 50 countries. PATIENTS: Patients with acute respiratory distress syndrome and at least 2 days of invasive mechanical ventilation and available data for the mode of mechanical ventilation and respiratory rate for the 2 first days. INTERVENTIONS: Analysis of patients with and without spontaneous breathing, defined by the mode of mechanical ventilation and by actual respiratory rate compared with set respiratory rate during the first 48 hours of mechanical ventilation. MEASUREMENTS AND MAIN RESULTS: Spontaneous breathing was present in 67% of patients with mild acute respiratory distress syndrome, 58% of patients with moderate acute respiratory distress syndrome, and 46% of patients with severe acute respiratory distress syndrome. Patients with spontaneous breathing were older and had lower acute respiratory distress syndrome severity, Sequential Organ Failure Assessment scores, ICU and hospital mortality, and were less likely to be diagnosed with acute respiratory distress syndrome by clinicians. In adjusted analysis, spontaneous breathing during the first 2 days was not associated with an effect on ICU or hospital mortality (33% vs 37%; odds ratio, 1.18 [0.92-1.51]; p = 0.19 and 37% vs 41%; odds ratio, 1.18 [0.93-1.50]; p = 0.196, respectively ). Spontaneous breathing was associated with increased ventilator-free days (13 [0-22] vs 8 [0-20]; p = 0.014) and shorter duration of ICU stay (11 [6-20] vs 12 [7-22]; p = 0.04). CONCLUSIONS: Spontaneous breathing is common in patients with acute respiratory distress syndrome during the first 48 hours of mechanical ventilation. Spontaneous breathing is not associated with worse outcomes and may hasten liberation from the ventilator and from ICU. Although these results support the use of spontaneous breathing in patients with acute respiratory distress syndrome independent of acute respiratory distress syndrome severity, the use of controlled ventilation indicates a bias toward use in patients with higher disease severity. In addition, because the lack of reliable data on inspiratory effort in our study, prospective studies incorporating the magnitude of inspiratory effort and adjusting for all potential severity confounders are required
Identifying associations between diabetes and acute respiratory distress syndrome in patients with acute hypoxemic respiratory failure: an analysis of the LUNG SAFE database
- Author
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- Shindhe S
- Shinn Iii Jo
- Shiozaki K
- Silesky Jimenez Ji
- Silesky J
- Sim M
- Simon P
- Simonis Fd
- Sivashanmugavel M
- Sjøbø Bå
- Sklienka P
- Smith Mj
- Smith O
- Soler Ja
- Solis-Quesada Je
- Sottiaux T
- Souissi Ab
- Spadaro S
- Srinivasa L
- Stamou Ee
- Staudinger T
- Stephenson L
- Stewart R
- Stigler W
- Strauch U
- Sula H
- Sun R
- Surbatovic M
- Suzuki H
- Symmonds S
- Synclair J
- Szakmany T
- Sánchez Rm
- Sánchez-Ballesteros J
- Søreide E
- Tabhan E
- Tabhan Ee
- Tainter C
- Takaba A
- Takada T
- Takagi S
- Tallet Alfonso Aa
- Tan Bc
- Tanaka H
- Tang R
- Tapponnier R
- Tarantino F
- Temprano S
- Terzi N
- Thibault S
- Thompson B. Taylor
- Thompson Mm
- Tibblin Ao
- Tinnirello A
- Tiribelli N
- Todeschini M
- Tomescu Dr
- Toribio Dp
- Toth-Tarsoly P
- Treanor N
- Trinidad Oa
- Tulaimat A
- Twohey L
- Uchiyama A
- Ueda T
- Ueno K
- Umbrello M
- Unnikrishnan R
- Uppalapati A
- Van Haren F
- Van Wezel Hm
- Vargas Mp
- Vascotto Er
- Vasquez Dn
- Vega Ld
- Veljovic M.
- Venti A
- Vercueil A
- Vermassen J
- Verstraete R
- Villagomez A
- Villagomez Aj
- Villamagua Bg
- Villar V
- Virgilio Cg
- Vitale Mn
- Volta Ca
- Wang C
- Wang Hx
- Wang Sh
- Wang W
- Warren J
- Watanabe E
- Watt P
- Welters Id
- Wenham T
- Wessbergh J
- Whitehead C
- Willett El
- Williams Aj
- Williams Ke
- Wise Mp
- Wittebole X
- Wong Hs
- Woods Pw
- Wrathall Dw
- Wrigge H
- Wu Yq
- Xin-Hua Q
- Xu Y
- Yamaguchi O
- Yamaji Y
- Yao Q
- Ye Zl
- Yeatts Dj
- Yu R
- Yu T
- Yu W
- Yumha Js
- Yuste Lj
- Zacharas Ga
- Zacharowski Kd
- Zani G
- Zantua Ks
- Zazu A
- Zeggwagh Aa
- Zeggwagh Aa
- Zein So
- Zender Ho
- Zhai Z
- Zhang F
- Zhang Xy
- Zhao H
- Zhao J
- Zhao Xy
- Zheng R
- Zhou Fc
- Zhou S
- Zhu Bh
- Zhu Wh
- Zogheib Eh
- Ñamendys-Silva Sa
- Ünal N
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2018
- Field of study
Background: Diabetes mellitus is a common co-existing disease in the critically ill. Diabetes mellitus may reduce the risk of acute respiratory distress syndrome (ARDS), but data from previous studies are conflicting. The objective of this study was to evaluate associations between pre-existing diabetes mellitus and ARDS in critically ill patients with acute hypoxemic respiratory failure (AHRF). Methods: An ancillary analysis of a global, multi-centre prospective observational study (LUNG SAFE) was undertaken. LUNG SAFE evaluated all patients admitted to an intensive care unit (ICU) over a 4-week period, that required mechanical ventilation and met AHRF criteria. Patients who had their AHRF fully explained by cardiac failure were excluded. Important clinical characteristics were included in a stepwise selection approach (forward and backward selection combined with a significance level of 0.05) to identify a set of independent variables associated with having ARDS at any time, developing ARDS (defined as ARDS occurring after day 2 from meeting AHRF criteria) and with hospital mortality. Furthermore, propensity score analysis was undertaken to account for the differences in baseline characteristics between patients with and without diabetes mellitus, and the association between diabetes mellitus and outcomes of interest was assessed on matched samples. Results: Of the 4107 patients with AHRF included in this study, 3022 (73.6%) patients fulfilled ARDS criteria at admission or developed ARDS during their ICU stay. Diabetes mellitus was a pre-existing co-morbidity in 913 patients (22.2% of patients with AHRF). In multivariable analysis, there was no association between diabetes mellitus and having ARDS (OR 0.93 (0.78-1.11); p = 0.39), developing ARDS late (OR 0.79 (0.54-1.15); p = 0.22), or hospital mortality in patients with ARDS (1.15 (0.93-1.42); p = 0.19). In a matched sample of patients, there was no association between diabetes mellitus and outcomes of interest. Conclusions: In a large, global observational study of patients with AHRF, no association was found between diabetes mellitus and having ARDS, developing ARDS, or outcomes from ARDS. Trial registration: NCT02010073. Registered on 12 December 2013
Epidemiology and patterns of tracheostomy practice in patients with acute respiratory distress syndrome in ICUs across 50 countries
- Author
- Abad RD
- Abe T
- Abe T.
- Abroug F
- Adams JC
- Adamsson RO
- Adolfsson A
- Aguilar RZ
- Aguirre JS
- Aguirre-Bermeo H
- Aisa TM
- Aisiku I
- Ajetunmobi OO
- Aker M
- Akyol OO
- Al Dorzi HM
- Al Jabbary AS
- Albaiceta GM
- Albarrak MM
- Albiero D
- Alda RS
- Alejandro RV
- Alexander P
- Algaba Á
- Aliaga FA
- Alisasis AU
- Allan RM
- Allue RM
- Almekhlafi G
- Alonso JG
- Altaf W
- Alvarez AM
- Alvarez J
- Amin P
- Amir F
- Amor M
- An Y
- Andersen FH
- Andoh K
- Andruszkiewicz P
- Aneman A
- Antonelli MM
- Antônio ACP
- Aoki N
- Appelberg H
- Arabi Y
- Arabi YM
- Arabim YM
- Araujo AM
- Arizmendi A
- Arnal JM
- Artiga MJD
- Artigas A
- Ascoli A
- Au SM
- Avila LE
- Azad R
- Azevedo LC
- Baboi L
- Badie JC
- Bailey IM
- Bailey MB
- Bajwa E
- Balkhi H
- Baltus T
- Banner-Goodspeed VM
- Barberet G
- Baron RM
- Baronia AK
- Barratt-Due A
- Barros FM
- Barros NC
- Batra H
- Battle CE
- Bauer PR
- Beck E
- Beck O
- Bedreag OH
- Beegle SH
- Beitler JR
- Bellani G
- Bellani G.
- Beloncle F
- Benslama A
- Beraldo DO
- Berghe C
- Berkelmans F
- Besset SL
- Bettini LR
- Beuret P
- Bezzi MG
- Bhardwaj VK
- Bhowmick K
- Biehler J
- Bigot C
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- Biondi RS
- Biscione RR
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- Borello SA
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- Stigler W
- Strauch U
- Sula H
- Sun R
- Surbatovic M
- Suzuki H
- Symmonds S
- Szakmany T
- Sánchez RM
- Sánchez-Ballesteros J
- Søreide E
- Tabhan E
- Tabhan EE
- Tainter C
- Takaba A
- Takada T
- Takagi S
- Tallet Alfonso AA
- Tamiya N.
- Tan Poland BC
- Tanaka H
- Tang R
- Tapponnier R
- Tarantino F
- Temprano S
- Terzi N
- Thibault S
- Thompson BT
- Thompson MM
- Tibblin AO
- Tinnirello A
- Tiribelli N
- Todeschini M
- Tomescu DR
- Toribio DP
- Toth-Tarsoly P
- Treanor N
- Trinidad OA
- Tulaimat A
- Twohey L
- Uchida M.
- Uchiyama A
- Ueda T
- Ueno K
- Umbrello M
- Unnikrishnan R
- Uppalapati A
- van Haren F
- Van Wezel HM
- Vargas MP
- Vascotto ER
- Vasquez DN
- Vega LD
- Veljovic M.
- Venti A
- Vercueil A
- Vermassen J
- Verstraete R
- Villagomez A
- Villagomez AJ
- Villamagua BG
- Villar V
- Vinzio M
- Virgilio CG
- Vitale MN
- Volta CA
- Wang C
- Wang HX
- Wang SH
- Wang W
- Warren J
- Watanabe E
- Watt P
- Welters ID
- Wenham T
- Wessbergh J
- Whitehead C
- Willett EL
- Williams AJ
- Williams KE
- Wise MP
- Wittebole X
- Wong HS
- Woods PW
- Wrathall DW
- Wrigge H
- Wu YQ
- Xin-Hua Q
- Xu Y
- Yamaguchi O
- Yamaji Y
- Yao Q
- Ye ZL
- Yeatts DJ
- Yu R
- Yu T
- Yu W
- Yumha JS
- Yuste LJ
- Zacharas GA
- Zacharowski KD
- Zani G
- Zantua KS
- Zazu A
- Zeggwagh AA
- Zein SO
- Zender HO
- Zhai Z
- Zhang F
- Zhang XY
- Zhao H
- Zhao J
- Zhao XY
- Zheng R
- Zhou FC
- Zhu BH
- Zhu WH
- Zogheib EH
- Ñamendys-Silva SA
- Ünal N
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2018
- Field of study
Background: To better understand the epidemiology and patterns of tracheostomy practice for patients with acute respiratory distress syndrome (ARDS), we investigated the current usage of tracheostomy in patients with ARDS recruited into the Large Observational Study to Understand the Global Impact of Severe Acute Respiratory Failure (LUNG-SAFE) study. Methods: This is a secondary analysis of LUNG-SAFE, an international, multicenter, prospective cohort study of patients receiving invasive or noninvasive ventilation in 50 countries spanning 5 continents. The study was carried out over 4 weeks consecutively in the winter of 2014, and 459 ICUs participated. We evaluated the clinical characteristics, management and outcomes of patients that received tracheostomy, in the cohort of patients that developed ARDS on day 1-2 of acute hypoxemic respiratory failure, and in a subsequent propensity-matched cohort. Results: Of the 2377 patients with ARDS that fulfilled the inclusion criteria, 309 (13.0%) underwent tracheostomy during their ICU stay. Patients from high-income European countries (n = 198/1263) more frequently underwent tracheostomy compared to patients from non-European high-income countries (n = 63/649) or patients from middle-income countries (n = 48/465). Only 86/309 (27.8%) underwent tracheostomy on or before day 7, while the median timing of tracheostomy was 14 (Q1-Q3, 7-21) days after onset of ARDS. In the subsample matched by propensity score, ICU and hospital stay were longer in patients with tracheostomy. While patients with tracheostomy had the highest survival probability, there was no difference in 60-day or 90-day mortality in either the patient subgroup that survived for at least 5 days in ICU, or in the propensity-matched subsample. Conclusions: Most patients that receive tracheostomy do so after the first week of critical illness. Tracheostomy may prolong patient survival but does not reduce 60-day or 90-day mortality. Trial registration: ClinicalTrials.gov, NCT02010073. Registered on 12 December 2013
Evaluation of MC1R high-throughput nucleotide sequencing data generated by the 1000 Genomes Project
- Author
- Aird D
- Aoki K
- Brandt DY
- Castelli EC
- Celso Teixeira Mendes-Junior
- Danecek P
- Erick da Cruz Castelli
- Ewens WJ
- Excoffier L
- Felipe VP
- Fu YX
- Ghiorzo P
- Gilissen C
- Harding RM
- Hider JL
- Hoffmann TJ
- Howie B
- Jablonski NG
- Jablonski NG
- Jimenez-Montero JA
- Khankhanian P
- Kumar S
- Leonardo Arduino Marano
- Letícia Marcorin
- Li H
- Matullo G
- Metzker ML
- Meynert AM
- Nagasaki H
- Nei M
- Nei M
- Nielsen R
- Nielsen R
- Pellegrini C
- Rees JL
- Rehm HL
- Robinson JT
- Savage SA
- Scheet P
- Slatkin M
- Sturm RA
- Sudmant PH
- Swope VB
- Tajima F
- Vigliar E
- Watterson GA
- Weigel KA
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease
- Author
- A Abbate
- A Abhyankar
- A Adams
- A Agafina
- A Akyea-Djamson
- A Alan
- A Alfieri
- A Alfrey
- A Alvarisqueta
- A Amos
- A Anadiotis
- A Anneveldt
- A Antolick
- A Arthur
- A Aslam
- Abaci F
- Abdullakutty J
- Abhaichand R
- Abib E Jr
- Aboufakher R
- Abrantes J
- Abreu M
- Abulencia K
- Acampora D
- Acampora M
- Accini Mendoza Jl
- Aceto L
- Acevedo B
- Acevedo L
- Acheatel R
- Actis Mv
- Adams M
- Adjic Nc
- Affaki Gs
- Agarwal Dk
- Aggarwal Rk
- Agosta Gf
- Aguilar M
- Aguilar M
- Ahire N
- Ahmad I
- Ahmed Sh
- Ahn Y
- Aish B
- Aiub F
- Aiub J
- Ajax K
- Ajioka M
- Akai Y
- Akatova E
- Akrap B
- Al Joundi T
- Al-Khalili F
- Albisu J
- Alcalde Jm
- Alcide P
- Alfonso T
- Allen J
- Alllison Dc
- Almaliky T
- Amerena J
- Andersen K
- Andor M
- Angelova I
- Angiolillo D
- Anita S
- Anker Sd
- Antalik L
- Antonicelli R
- Aparicio Cv
- Apel T
- Apostolovic S
- Ara M
- Aragorn L
- Arango Jl
- Araujo Fonseca M
- Ardissino D
- Arenas Leon Jl
- Arevalo S
- Argiolas G
- Arif I
- Armas E
- Aron G
- Arora S
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- Ashcom T
- Ashford M
- Ashino K
- Asim Oktay Ao
- Assarsson E
- Ata B
- Ather N
- Atieh M
- Aull L
- Avalos V
- Avdonina N
- Awasthi Ak
- Axthelm C
- Ayala M
- Ayasse D
- Ayasse M
- Azizad M
- Azize Gm
- B Becker
- Baar M
- Babu R
- Backer T
- Badea C
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- Bagi Es
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- Baldin Mg
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- Ballantyne C
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- Balode A
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- Banker D
- Banker K
- Baquero A
- Barbarash Ol
- Barbato E
- Barbosa E
- Barnett S
- Baron S
- Barreto M
- Barroso A
- Barroso W
- Bartkowiak A
- Bartosh L
- Bartuseviciene S
- Bashir K
- Baszak J
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- Bayram E
- Beall K
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- Bender D
- Benedetti G
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- Bevilacqua Mt
- Bhadade S
- Bilazarian S
- Bilodeau N
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- Bitzer V
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- Blazsek Z
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- Bluemel J
- Blumberg C
- Blumenthal R
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- Brath H
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- C Conradie
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- C Covert
- C Cuneo
- Caballero-Valiente B
- Cabau Jr
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- Campanale Eg
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- CANTOS Trial Group. Krum H
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- Chachalis G
- Chaggar S
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- Chamblee T
- Chang K
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- Chang Wh
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- Chattin W
- Chauhan D
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- Chaussé I
- Chavada J
- Chaverra I
- Chaware G
- Chee L
- Chella S
- Chen Cp
- Chen J
- Chen Mh
- Chen Y
- Chen Yc
- Chen Zc
- Cheng Jj
- Cheng S
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- Cherlin R
- Cheung D
- Chhabra A
- Chintala P
- Chiodi L
- Choi Aj
- Chou S
- Chouinard G
- Christensen L
- Christenson S
- Chung A
- Churina S
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- Cioffi A
- Cislowski D
- Cleveland T
- Clocotan M
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- Colfer H
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- Cornel Jh
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- Czerski T
- D'Amours Dg
- D Dash
- D Dattani
- D Denham
- D Desai
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- Da Silva A
- Da Silva D Jr
- Da Silva O Jr
- Dahlen G
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- Dawood Sy
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- Destro M
- Dettmer M
- Devasia T
- Deweerdt N
- Dhanak R
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- Di Biase M
- Diago M
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- Diller P
- Dimattia M
- Dimitrov G
- Diodati J
- Dobariya H
- Dobilas V
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- Doesborg L
- Doggett J
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- Dommerholt R
- Donahue K
- Donath M
- Donaubauer T
- Dong X
- Dormidontova G
- Dorogova I
- Dos Santos A
- Dos Santos F
- Dos Santos P
- Doughty A
- Doughty L
- Dovgalevskiy Y
- Dovgolis S
- Dragutksy B
- Dreese M
- Drost I
- Drouin K
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- Dwenger E
- Dzupina A
- Dékány Jn
- E Eleuteri
- E Englmann
- Earl J
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- Echeverria L
- Eder F
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- Einhorn D
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- Ellenbroek D
- Ellis M
- Emil B
- Endo T
- Engelen W
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- Fitilev S
- Fitz-Patrick D
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- Flaksa I
- Flather M
- Flezar M
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- Flores E
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- Foerster A
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- Fonseca A
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- Forgosh L
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- Frankenstein L
- Fratczak M
- Freitas E
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- Fruchter G
- Fu G
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- Fullerton D
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- Goette A
- Goff R
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- Gonsorcik J
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- Gordeev I
- Gorges R
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- Grigaraviciene I
- Grigorova V
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- Grover A
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- Gutmann J
- Guzman I
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- Gyorgyova E
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- H Hansen
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- Hagenow A
- Hagiwara Y
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- I Ivanov
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- Ichisawa M
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- Infusino F
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- Zineldine A.
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- Publication venue
- 'Massachusetts Medical Society'
- Publication date
- 01/01/2017
- Field of study
Background: Experimental and clinical data suggest that reducing inflammation without affecting lipid levels may reduce the risk of cardiovascular disease. Yet, the inflammatory hypothesis of atherothrombosis has remained unproved. Methods: We conducted a randomized, double-blind trial of canakinumab, a therapeutic monoclonal antibody targeting interleukin-1β, involving 10,061 patients with previous myocardial infarction and a high-sensitivity C-reactive protein level of 2 mg or more per liter. The trial compared three doses of canakinumab (50 mg, 150 mg, and 300 mg, administered subcutaneously every 3 months) with placebo. The primary efficacy end point was nonfatal myocardial infarction, nonfatal stroke, or cardiovascular death. RESULTS: At 48 months, the median reduction from baseline in the high-sensitivity C-reactive protein level was 26 percentage points greater in the group that received the 50-mg dose of canakinumab, 37 percentage points greater in the 150-mg group, and 41 percentage points greater in the 300-mg group than in the placebo group. Canakinumab did not reduce lipid levels from baseline. At a median follow-up of 3.7 years, the incidence rate for the primary end point was 4.50 events per 100 person-years in the placebo group, 4.11 events per 100 person-years in the 50-mg group, 3.86 events per 100 person-years in the 150-mg group, and 3.90 events per 100 person-years in the 300-mg group. The hazard ratios as compared with placebo were as follows: in the 50-mg group, 0.93 (95% confidence interval [CI], 0.80 to 1.07; P = 0.30); in the 150-mg group, 0.85 (95% CI, 0.74 to 0.98; P = 0.021); and in the 300-mg group, 0.86 (95% CI, 0.75 to 0.99; P = 0.031). The 150-mg dose, but not the other doses, met the prespecified multiplicity-adjusted threshold for statistical significance for the primary end point and the secondary end point that additionally included hospitalization for unstable angina that led to urgent revascularization (hazard ratio vs. placebo, 0.83; 95% CI, 0.73 to 0.95; P = 0.005). Canakinumab was associated with a higher incidence of fatal infection than was placebo. There was no significant difference in all-cause mortality (hazard ratio for all canakinumab doses vs. placebo, 0.94; 95% CI, 0.83 to 1.06; P = 0.31). Conclusions: Antiinflammatory therapy targeting the interleukin-1β innate immunity pathway with canakinumab at a dose of 150 mg every 3 months led to a significantly lower rate of recurrent cardiovascular events than placebo, independent of lipid-level lowering. (Funded by Novartis; CANTOS ClinicalTrials.gov number, NCT01327846.
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