Cyclometallated Platinum(II) Complexes Featuring an Unusual, C^N‐Coordinating Pyridyl‐pyridylidene Ligand and L X Coligands: Synthesis, Structures and Dual Luminescence Behavior

Thanks to an unusual protodemethylation reaction, a series of luminescent cyclometallated platinum(II) complexes can be prepared, which incorporate a rare NC-chelating, pyridyl-pyridylidene ligand, in combination with OO-coordinating acetylacetonate (acac) or NO-coordinating 2-picolinate (pic) or 8-hydroxyquinolate. The acac and pic complexes show unusual dual emission in a frozen glass.A series of cyclometallated platinum(II) complexes incorporating a rare, N^C-chelating, pyridyl-pyridylidene ligand are described, in which the coordination sphere is completed by two chlorides or an L X co-ligand, namely O O-coordinating acetylacetonate (acac), or N^O-coordinating 2-picolinate (pic) or 8-hydroxyquinolinate. The acac and pic complexes have been structurally characterized in the solid state by single-crystal X-ray diffraction. These two complexes display red phosphorescence in the solid state at room temperature. In a frozen glass at 77 K, all four complexes show two broad emission bands that span much of the visible spectrum, apparently from two unequilibrated excited states

موقف القرآن من تمكين المرأة = The Qur’an’s position on empowering women

مِنَ النّادر أن نجد قضية اختلفت فيها وجهات النظر بمثل ما اختلفت وتعدّدت في قضية استقواء المرأة (Women Empowerment)، فقضية المرأة وتأهيلها وتمكينها هي قضية المجتمع البشري كله، ولهذا فإن هذه القضية التي تعدّدت فيها التشريعات ووجهات نظر المفكرين والفلاسفة ودُعَاة الإصلاح على مرّ العصور، حتى وصل التعدد إلى مستوى التناقض والاختلاف الجذري الذي لا إمكان معه للقاء أو اتفاق أو تقارب. فهناك تيار متشدد أصابه الغلو والرضوخ لمنظومة فكرية دينية منغلقة، وهناك تيار ليبيرالي علماني يتماشى مع المنظومة الغربية المنحلة. ويأتي هذا البحث ليناقش هذه القضية بأسلوب علمي منهجي، حيث يعتمد على المنهج الاستقرائي ليتتبع الآراء من بطون كتب التفسير والكتب العلمية الحديثة ثم المنهج التحليلي حيث تتم المناقشة والدراسة لجميع الآراء والوصول إلى نتائج علمية صحيحة، ومن هذه النتائج ما يأتي: أن المقصود القرآني بتمكين المرأة هو: غرس وعي وإدراك لإحياء مسألة إجرائية تعالج حقاً إنسانياً وشأناً تنموياً للمرأة. وكلما أخذ العنصر النسائي فرصته في البناء والتنمية والثقافة من أجل سعادة أكبر للأسرة والمجتمع والدولة. ************************************************************************************ It is rare to find a case in which the views differed in the same way as in the issue of women's Empowerment. The issue of women, their rehabilitation, and empowerment is the issue of the entire human community. Hence, this issue in which legislation and the viewpoints of thinkers, philosophers, and advocates of reform have multiplied throughout the ages until the multiplicity has reached the level of contradiction and radical disagreement with which there is no possibility of meeting, agreement, or convergence. This research comes to discuss this issue in a systematic scientific manner, as it relies on the inductive approach to trace opinions from the stomachs of tafsir books and modern scientific books, then the analytical method, where discussion and study of all opinions and access to valid scientific results are done, and among these results are the following: The greatest purpose of Islam is the aim of justice and equality, and that it came to achieve equality among people in the matter of rights and duties, and it did not present gender over gender or race over race. The Qur’ān never meant by empowering women to overcome men because they control the nature of the relationship between them, and therefore there must be a revolution against religion, language, culture, customs, traditions, and history. The intention is to make her happy by taking her rights and fulfilling her legitimate duties towards herself, her husband, and her parents, and she participates in building the society in which she lives in constructive and civilized participation that preserves her value and position that God has given her

الضوابط النقلية لفهم سور القرآن الكريم = Agreed rules for understanding the Holy Quran

يهدف هذا البحث إلى الكشف عن الضوابط النقلية المعينة على معرفة مقصد السور القرآنية ذات الموضوعات المتعددة والتي ظاهرها التعارض، ويوضح البحث الضوابط النقلية التي يمكن أن تكون منهجا يمكن الاعتماد عليه في التفسير الموضوعي. كما حاول البحث تطبيق هذه القواعد على ثلاث سور من القرآن الكريم وهي الأنعام ويونس والأحزاب. واستخدم البحث المنهج الاستقرائي بتتبع كل ما يتعلق بالتفسير الموضوعي للسورة في كتب التفسير بمختلف مناهجها، والأحاديث النبوية، والآثار ذات الصلة بالموضوع، وكذلك كتب التفسير بالرأي على أنواعها؛ كما استخدم المنهج التحليلي وذلك بدراسة الظاهرة ونقد الأطروحات غير الواضحة مع استنباط ضوابط منهجية معينة على فهم السور القرآنية. وقد توصل البحث إلى عدد من النتائج، من أهمها أن السورة القرآنية لها وحدة موضوعية ومقصد رئيس تنتظم تحته القصص والأمثال والأحكام الشرعية الواردة في السورة. كما توصل البحث إلى ضرورة الاستفادة من المخزون العلمي الذي تركه المفسرون وتوظيف ذلك في خدمة البحث الموضوعي عن مقصد السور القرآنية. كم أثبت البحث أن الاعتناء بالكتابة في ضوابط التفسير الموضوعي وتكوين مرجعية للباحثين في مقاصد السور له من الأهمية ما للضوابط الفقهية والأصولية التي سبقت الضوابط التفسيرية وتم تأصيلها وتأطيرها بشكل واضح، ذكل أن كتابة تفاسير تقوم على أساس مقصدي محدد بضوابط منهجية للسور القرآنية يكون له أبلغ الأثر على من يرغب في فهمها من خلال الوقوف على الترابط المحكم فيها. ******************************************************************************* This research aims to reveal the specific controls on knowing the purpose of the Qur'anic surahs with multiple topics, which are apparent contradictions. On the other hand, the research applied the rules laid down on three chapters of the Holy Qur’an, which are Al Anam, Younis, and Al Ahzab. The research used the inductive method to track everything related to the objective interpretation of the Surah in the books of interpretation in its various curricula, the hadiths of the Prophet, and the effects related to the topic, as well as books of interpretation of opinion on various types; also the analytical method was used by studying the phenomenon and criticizing unclear theses with devising certain methodological controls on understanding the Quranic Surahs. The research also reached a number of results, the most important of which is that the Qur'an surah has an objective unity and a main purpose under which the stories, proverbs and legal rulings mentioned in the surah are organized. The research also reached the necessity of making use of the scientific repository left by the interpreters and employing this in the service of objective research on the purpose of the Qur'anic surahs. How much research proved that caring for writing in the controls of objective interpretation and forming a reference for researchers in the purposes of the fence has important importance for the doctrinal and fundamentalist controls that preceded the explanatory controls and were clearly rooted and framed, as writing interpretations based on a specific purpose with systematic controls of the Quranic fence has the most impact. It is upon those who wish to understand it by identifying the tight linkages therein

Antimicrobial resistance among migrants in Europe: a systematic review and meta-analysis

BACKGROUND: Rates of antimicrobial resistance (AMR) are rising globally and there is concern that increased migration is contributing to the burden of antibiotic resistance in Europe. However, the effect of migration on the burden of AMR in Europe has not yet been comprehensively examined. Therefore, we did a systematic review and meta-analysis to identify and synthesise data for AMR carriage or infection in migrants to Europe to examine differences in patterns of AMR across migrant groups and in different settings. METHODS: For this systematic review and meta-analysis, we searched MEDLINE, Embase, PubMed, and Scopus with no language restrictions from Jan 1, 2000, to Jan 18, 2017, for primary data from observational studies reporting antibacterial resistance in common bacterial pathogens among migrants to 21 European Union-15 and European Economic Area countries. To be eligible for inclusion, studies had to report data on carriage or infection with laboratory-confirmed antibiotic-resistant organisms in migrant populations. We extracted data from eligible studies and assessed quality using piloted, standardised forms. We did not examine drug resistance in tuberculosis and excluded articles solely reporting on this parameter. We also excluded articles in which migrant status was determined by ethnicity, country of birth of participants' parents, or was not defined, and articles in which data were not disaggregated by migrant status. Outcomes were carriage of or infection with antibiotic-resistant organisms. We used random-effects models to calculate the pooled prevalence of each outcome. The study protocol is registered with PROSPERO, number CRD42016043681. FINDINGS: We identified 2274 articles, of which 23 observational studies reporting on antibiotic resistance in 2319 migrants were included. The pooled prevalence of any AMR carriage or AMR infection in migrants was 25·4% (95% CI 19·1-31·8; I2 =98%), including meticillin-resistant Staphylococcus aureus (7·8%, 4·8-10·7; I2 =92%) and antibiotic-resistant Gram-negative bacteria (27·2%, 17·6-36·8; I2 =94%). The pooled prevalence of any AMR carriage or infection was higher in refugees and asylum seekers (33·0%, 18·3-47·6; I2 =98%) than in other migrant groups (6·6%, 1·8-11·3; I2 =92%). The pooled prevalence of antibiotic-resistant organisms was slightly higher in high-migrant community settings (33·1%, 11·1-55·1; I2 =96%) than in migrants in hospitals (24·3%, 16·1-32·6; I2 =98%). We did not find evidence of high rates of transmission of AMR from migrant to host populations. INTERPRETATION: Migrants are exposed to conditions favouring the emergence of drug resistance during transit and in host countries in Europe. Increased antibiotic resistance among refugees and asylum seekers and in high-migrant community settings (such as refugee camps and detention facilities) highlights the need for improved living conditions, access to health care, and initiatives to facilitate detection of and appropriate high-quality treatment for antibiotic-resistant infections during transit and in host countries. Protocols for the prevention and control of infection and for antibiotic surveillance need to be integrated in all aspects of health care, which should be accessible for all migrant groups, and should target determinants of AMR before, during, and after migration. FUNDING: UK National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare Charity, the Wellcome Trust, and UK National Institute for Health Research Health Protection Research Unit in Healthcare-associated Infections and Antimictobial Resistance at Imperial College London

A ternary PEDOT-TiO2-reduced graphene oxide nanocomposite for supercapacitor applications

A ternary composite of PEDOT was prepared with TiO2 via emulsion polymerization method adjusting various weight ratios of TiO2 to PEDOT and synthesized rGO was then blended with this composite. The FTIR, UV–Vis and XRD analysis displayed characteristic features of PEDOT and TiO2. The morphology of the nano-hybrid structure was additionally investigated by SEM analysis. Pore size and surface area analysis of particles were characterized by BET method. The electrochemical analysis showed that the specific capacitance (Csp) for PEDOT-TiO2-15-rGO was 18.9 F.cm-2 at 0.1 mA g-1 current density

Surgical site infection after gastrointestinal surgery in high-income, middle-income, and low-income countries: a prospective, international, multicentre cohort study

Background: Surgical site infection (SSI) is one of the most common infections associated with health care, but its importance as a global health priority is not fully understood. We quantified the burden of SSI after gastrointestinal surgery in countries in all parts of the world. Methods: This international, prospective, multicentre cohort study included consecutive patients undergoing elective or emergency gastrointestinal resection within 2-week time periods at any health-care facility in any country. Countries with participating centres were stratified into high-income, middle-income, and low-income groups according to the UN's Human Development Index (HDI). Data variables from the GlobalSurg 1 study and other studies that have been found to affect the likelihood of SSI were entered into risk adjustment models. The primary outcome measure was the 30-day SSI incidence (defined by US Centers for Disease Control and Prevention criteria for superficial and deep incisional SSI). Relationships with explanatory variables were examined using Bayesian multilevel logistic regression models. This trial is registered with ClinicalTrials.gov, number NCT02662231. Findings: Between Jan 4, 2016, and July 31, 2016, 13 265 records were submitted for analysis. 12 539 patients from 343 hospitals in 66 countries were included. 7339 (58·5%) patient were from high-HDI countries (193 hospitals in 30 countries), 3918 (31·2%) patients were from middle-HDI countries (82 hospitals in 18 countries), and 1282 (10·2%) patients were from low-HDI countries (68 hospitals in 18 countries). In total, 1538 (12·3%) patients had SSI within 30 days of surgery. The incidence of SSI varied between countries with high (691 [9·4%] of 7339 patients), middle (549 [14·0%] of 3918 patients), and low (298 [23·2%] of 1282) HDI (p < 0·001). The highest SSI incidence in each HDI group was after dirty surgery (102 [17·8%] of 574 patients in high-HDI countries; 74 [31·4%] of 236 patients in middle-HDI countries; 72 [39·8%] of 181 patients in low-HDI countries). Following risk factor adjustment, patients in low-HDI countries were at greatest risk of SSI (adjusted odds ratio 1·60, 95% credible interval 1·05–2·37; p=0·030). 132 (21·6%) of 610 patients with an SSI and a microbiology culture result had an infection that was resistant to the prophylactic antibiotic used. Resistant infections were detected in 49 (16·6%) of 295 patients in high-HDI countries, in 37 (19·8%) of 187 patients in middle-HDI countries, and in 46 (35·9%) of 128 patients in low-HDI countries (p < 0·001). Interpretation: Countries with a low HDI carry a disproportionately greater burden of SSI than countries with a middle or high HDI and might have higher rates of antibiotic resistance. In view of WHO recommendations on SSI prevention that highlight the absence of high-quality interventional research, urgent, pragmatic, randomised trials based in LMICs are needed to assess measures aiming to reduce this preventable complication

MUSiC : a model-unspecific search for new physics in proton-proton collisions at root s=13TeV

Results of the Model Unspecific Search in CMS (MUSiC), using proton-proton collision data recorded at the LHC at a centre-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 35.9 fb(-1), are presented. The MUSiC analysis searches for anomalies that could be signatures of physics beyond the standard model. The analysis is based on the comparison of observed data with the standard model prediction, as determined from simulation, in several hundred final states and multiple kinematic distributions. Events containing at least one electron or muon are classified based on their final state topology, and an automated search algorithm surveys the observed data for deviations from the prediction. The sensitivity of the search is validated using multiple methods. No significant deviations from the predictions have been observed. For a wide range of final state topologies, agreement is found between the data and the standard model simulation. This analysis complements dedicated search analyses by significantly expanding the range of final states covered using a model independent approach with the largest data set to date to probe phase space regions beyond the reach of previous general searches.Peer reviewe

Measurement of prompt open-charm production cross sections in proton-proton collisions at root s=13 TeV

The production cross sections for prompt open-charm mesons in proton-proton collisions at a center-of-mass energy of 13TeV are reported. The measurement is performed using a data sample collected by the CMS experiment corresponding to an integrated luminosity of 29 nb(-1). The differential production cross sections of the D*(+/-), D-+/-, and D-0 ((D) over bar (0)) mesons are presented in ranges of transverse momentum and pseudorapidity 4 < p(T) < 100 GeV and vertical bar eta vertical bar < 2.1, respectively. The results are compared to several theoretical calculations and to previous measurements.Peer reviewe