436 research outputs found
Effects of inhomogeneous broadening on reflection spectra of Bragg multiple quantum well structures with a defect
The reflection spectrum of a multiple quantum well structure with an inserted
defect well is considered. The defect is characterized by the exciton frequency
different from that of the host's wells. It is shown that for relatively short
structures, the defect produces significant modifications of the reflection
spectrum, which can be useful for optoelectronic applications. Inhomogeneous
broadening is shown to affect the spectrum in a non-trivial way, which cannot
be described by the standard linear dispersion theory. A method of measuring
parameters of both homogeneous and inhomogeneous broadenings of the defect well
from a single CW reflection spectrum is suggested.Comment: 27 pages, 6 eps figures; RevTe
Strategies to acquire and use phosphorus in phosphorus-impoverished and fire-prone environments
Published online: 19 May 2022Background Unveiling the diversity of plant strategies to acquire and use phosphorus (P) is crucial to understand factors promoting their coexistence in hyperdiverse P-impoverished communities within fire-prone landscapes such as in cerrado (South America), fynbos (South Africa) and kwongan (Australia). Scope We explore the diversity of P-acquisition strategies, highlighting one that has received little attention: acquisition of P following fires that temporarily enrich soil with P. This strategy is expressed by fire ephemerals as well as fast-resprouting perennial shrubs. A plant’s leaf manganese concentration ([Mn]) provides significant clues on P-acquisition strategies. High leaf [Mn] indicates carboxylatereleasing P-acquisition strategies, but other exudates may play the same role as carboxylates in P acquisition. Intermediate leaf [Mn] suggests facilitation of P acquisition by P-mobilising neighbours, through release of carboxylates or functionally similar compounds. Very low leaf [Mn] indicates that carboxylates play no immediate role in P acquisition. Release of phosphatases also represents a P-mining strategy, mobilising organic P. Some species may express multiple strategies, depending on time since germination or since fire, or on position in the landscape. In severely P-impoverished landscapes, photosynthetic P-use efficiency converges among species. Efficient species exhibit rapid rates of photosynthesis at low leaf P concentrations. A high P-remobilisation efficiency from senescing organs is another way to use P efficiently, as is extended longevity of plant organs. Conclusions Many P-acquisition strategies coexist in P-impoverished landscapes, but P-use strategies tend to converge. Common strategies of which we know little are those expressed by ephemeral or perennial species that are the first to respond after a fire. We surmise that carboxylate-releasing P-mobilising strategies are far more widespread than envisaged so far, and likely expressed by species that accumulate metals, exemplified by Mn, metalloids, such as selenium, fluorine, in the form of fluoroacetate, or silicon. Some carboxylate-releasing strategies are likely important to consider when restoring sites in biodiverse regions as well as in cropping systems on P-impoverished or strongly P-sorbing soils, because some species may only be able to establish themselves next to neighbours that mobilise P.Hans Lambers, Patrícia de Britto Costa, Gregory R. Cawthray, Matthew D. Denton, Patrick M. Finnegan, Patrick E. Hayes, Rafael S. Oliveira, Simon C. Power, Kosala Ranathunge, Qi Shen, Xiao Wang, Hongtao Zhon
Common variants near MC4R are associated with fat mass, weight and risk of obesity.
To identify common variants influencing body mass index (BMI), we analyzed genome-wide association data from 16,876 individuals of European descent. After previously reported variants in FTO, the strongest association signal (rs17782313, P = 2.9 x 10(-6)) mapped 188 kb downstream of MC4R (melanocortin-4 receptor), mutations of which are the leading cause of monogenic severe childhood-onset obesity. We confirmed the BMI association in 60,352 adults (per-allele effect = 0.05 Z-score units; P = 2.8 x 10(-15)) and 5,988 children aged 7-11 (0.13 Z-score units; P = 1.5 x 10(-8)). In case-control analyses (n = 10,583), the odds for severe childhood obesity reached 1.30 (P = 8.0 x 10(-11)). Furthermore, we observed overtransmission of the risk allele to obese offspring in 660 families (P (pedigree disequilibrium test average; PDT-avg) = 2.4 x 10(-4)). The SNP location and patterns of phenotypic associations are consistent with effects mediated through altered MC4R function. Our findings establish that common variants near MC4R influence fat mass, weight and obesity risk at the population level and reinforce the need for large-scale data integration to identify variants influencing continuous biomedical traits
Search for Lepton Flavor Violating tau Decays into Three Leptons
We search for lepton-flavor-violating tau decays into three leptons (electron
or muon) using 535 fb-1 of data collected with the Belle detector at the KEKB
asymmetric-energy e+e- collider. No evidence for these decays is observed, and
we set 90% confidence level upper limits on the branching fractions of
(2.0-4.1)x10^-8. These results improve upon our previously published upper
limits by factors of 4.9 to 10.Comment: 11 pages, 4 figures, submitted to Phys. Lett.
Search for lepton flavor violating decays tau- -> l- pi0, l- eta, l- eta'
We have searched for lepton flavor violating semileptonic tau decays using a
data sample of 153.8/fb accumulated with the Belle detector at the KEKB e+e-
collider. For the six decay modes studied, the observed yield is compatible
with the estimated background and the following upper limits are set at the 90%
confidence level: B(tau- -> e- eta) mu- eta) < 1.5 x
10^-7, B(tau- -> e- pi0) mu- pi0) < 4.1 x 10^-7,
B(tau- -> e- eta') mu- eta') < 4.7 x 10^-7. These
results are 10 to 64 times more restrictive than previous limits.Comment: 14 pages, 13 figures, RevTex
Meta-analysis of type 2 Diabetes in African Americans Consortium
Type 2 diabetes (T2D) is more prevalent in African Americans than in Europeans. However, little is known about the genetic risk in African Americans despite the recent identification of more than 70 T2D loci primarily by genome-wide association studies (GWAS) in individuals of European ancestry. In order to investigate the genetic architecture of T2D in African Americans, the MEta-analysis of type 2 DIabetes in African Americans (MEDIA) Consortium examined 17 GWAS on T2D comprising 8,284 cases and 15,543 controls in African Americans in stage 1 analysis. Single nucleotide polymorphisms (SNPs) association analysis was conducted in each study under the additive model after adjustment for age, sex, study site, and principal components. Meta-analysis of approximately 2.6 million genotyped and imputed SNPs in all studies was conducted using an inverse variance-weighted fixed effect model. Replications were performed to follow up 21 loci in up to 6,061 cases and 5,483 controls in African Americans, and 8,130 cases and 38,987 controls of European ancestry. We identified three known loci (TCF7L2, HMGA2 and KCNQ1) and two novel loci (HLA-B and INS-IGF2) at genome-wide significance (4.15 × 10(-94)<P<5 × 10(-8), odds ratio (OR) = 1.09 to 1.36). Fine-mapping revealed that 88 of 158 previously identified T2D or glucose homeostasis loci demonstrated nominal to highly significant association (2.2 × 10(-23) < locus-wide P<0.05). These novel and previously identified loci yielded a sibling relative risk of 1.19, explaining 17.5% of the phenotypic variance of T2D on the liability scale in African Americans. Overall, this study identified two novel susceptibility loci for T2D in African Americans. A substantial number of previously reported loci are transferable to African Americans after accounting for linkage disequilibrium, enabling fine mapping of causal variants in trans-ethnic meta-analysis studies.Peer reviewe
Combination of searches for Higgs boson pairs in pp collisions at \sqrts = 13 TeV with the ATLAS detector
This letter presents a combination of searches for Higgs boson pair production using up to 36.1 fb(-1) of proton-proton collision data at a centre-of-mass energy root s = 13 TeV recorded with the ATLAS detector at the LHC. The combination is performed using six analyses searching for Higgs boson pairs decaying into the b (b) over barb (b) over bar, b (b) over barW(+)W(-), b (b) over bar tau(+)tau(-), W+W-W+W-, b (b) over bar gamma gamma and W+W-gamma gamma final states. Results are presented for non-resonant and resonant Higgs boson pair production modes. No statistically significant excess in data above the Standard Model predictions is found. The combined observed (expected) limit at 95% confidence level on the non-resonant Higgs boson pair production cross-section is 6.9 (10) times the predicted Standard Model cross-section. Limits are also set on the ratio (kappa(lambda)) of the Higgs boson self-coupling to its Standard Model value. This ratio is constrained at 95% confidence level in observation (expectation) to -5.0 < kappa(lambda) < 12.0 (-5.8 < kappa(lambda) < 12.0). In addition, limits are set on the production of narrow scalar resonances and spin-2 Kaluza-Klein Randall-Sundrum gravitons. Exclusion regions are also provided in the parameter space of the habemus Minimal Supersymmetric Standard Model and the Electroweak Singlet Model. For complete list of authors see http://dx.doi.org/10.1016/j.physletb.2019.135103</p
Searches for lepton-flavour-violating decays of the Higgs boson in TeV collisions with the ATLAS detector
This Letter presents direct searches for lepton flavour violation in Higgs boson decays, H → eτ and
H → μτ , performed with the ATLAS detector at the LHC. The searches are based on a data sample
of proton–proton collisions at a centre-of-mass energy √s = 13 TeV, corresponding to an integrated
luminosity of 36.1 fb−1. No significant excess is observed above the expected background from Standard
Model processes. The observed (median expected) 95% confidence-level upper limits on the leptonflavour-violating branching ratios are 0.47% (0.34+0.13−0.10%) and 0.28% (0.37+0.14−0.10%) for H → eτ and H → μτ , respectively.publishedVersio
- …