Politik mit der Armut: Notizen zu Weimarer Perspektiven anläßlich bundesrepublikanischer Wirklichkeiten.

Das System der Sozialpolitik, verstanden als eine Pufferzone (Vobruba 1983: 65 ff.) zwischen Kapital und Lohnarbeit, hat nur insoweit eine gewisse Selbständigkeit, als sich auch in Krisenzeiten die in dieses System eingezogenen Mindestplafonds durchhalten lassen, und zwar kontrakonjunkturellwie kontrastrukturell. Auf andere Weise kann einem Sinken der Einkommenspyramide, der Pyramide von Lohn- und Sozialeinkommen also, kein Einhalt geboten werden. Das schwächste Glied bestimmt auch hier die Reißfestigkeit der Kette, eben des Systemsm der Sozialpolitik. Diese Pufferzonen konnten in der Weltwirtschaftskrise weder im Bereich der Arbeitslosenversicherung (Preller 1978: 418 ff.; Adamy/Steffen 1983, 1982) noch dem der Fürsorge (Leibfried 1981 a; Hansen u.a. 1982) gehalten werden. Auch in der heutigen Krise des Transfersystems, also des Systems der sozialen Sicherung (Schäfer 1983), sind sie, wenn auch in anderer Gewichtung, akut bedroht. Die sozialpolitische Trendwende, die in den 70er Jahren begann, hat sowohl in der Arbeitslosenversicherung (Hauser u.a. 1984) als auch in der Sozialhilfe (Adamy/Naegele 1983; Galperin 1984) tiefe Spuren hinterlassen

Growth response to 4-hydroxy-l-threonine of Escherichia coli mutants blocked in vitamin B6 biosynthesis

AbstractMutants of Escherichia coli (pdx B and pdx C) which are blocked in the biosynthesis of pyridoxol (vitamin B6) showed a growth response to 4-hydroxy-l-threonine. This observation constitutes the first direct evidence in support of the view that 4-hydroxy-l-threonine is implicated in the biosynthesis of vitamin B6. 1-Aminopropan-2,3-diol, the decarboxylation product of 4-hydroxy-l-threonine, does not support the growth of these mutants. Deuterium from deuterium-labelled 1-aminopropan-2,3-diol was not incorporated into pyridoxol

Parametric estimation of the driving L\'evy process of multivariate CARMA processes from discrete observations

We consider the parametric estimation of the driving L\'evy process of a multivariate continuous-time autoregressive moving average (MCARMA) process, which is observed on the discrete time grid $(0,h,2h,...)$. Beginning with a new state space representation, we develop a method to recover the driving L\'evy process exactly from a continuous record of the observed MCARMA process. We use tools from numerical analysis and the theory of infinitely divisible distributions to extend this result to allow for the approximate recovery of unit increments of the driving L\'evy process from discrete-time observations of the MCARMA process. We show that, if the sampling interval $h=h_N$ is chosen dependent on $N$, the length of the observation horizon, such that $N h_N$ converges to zero as $N$ tends to infinity, then any suitable generalized method of moments estimator based on this reconstructed sample of unit increments has the same asymptotic distribution as the one based on the true increments, and is, in particular, asymptotically normally distributed.Comment: 38 pages, four figures; to appear in Journal of Multivariate Analysi

Identification and characterisation of two high-affinity glucose transporters from the spoilage yeast Brettanomyces bruxellensis

The yeast Brettanomyces bruxellensis (syn. Dekkera bruxellensis) is an emerging and undesirable contaminant in industrial low-sugar ethanol fermentations that employ the yeast Saccharomyces cerevisiae. High-affinity glucose import in B. bruxellensis has been proposed to be the mechanism by which this yeast can outcompete S. cerevisiae. The present study describes the characterization of two B. bruxellensis genes (BHT1 and BHT3) believed to encode putative high-affinity glucose transporters. In vitro-generated transcripts of both genes as well as the S. cerevisiae HXT7 high-affinity glucose transporter were injected into Xenopus laevis oocytes and subsequent glucose uptake rates were assayed using 14C-labelled glucose. At 0.1 mM glucose, Bht1p was shown to transport glucose five times faster than Hxt7p. pH affected the rate of glucose transport by Bht1p and Bht3p, indicating an active glucose transport mechanism that involves proton symport. These results suggest a possible role for BHT1 and BHT3 in the competitive ability of B. bruxellensis

Plasma extracellular vesicle tau and TDP-43 as diagnostic biomarkers in FTD and ALS

Minimally invasive biomarkers are urgently needed to detect molecular pathology in frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS). Here, we show that plasma extracellular vesicles (EVs) contain quantifiable amounts of TDP-43 and full-length tau, which allow the quantification of 3-repeat (3R) and 4-repeat (4R) tau isoforms. Plasma EV TDP-43 levels and EV 3R/4R tau ratios were determined in a cohort of 704 patients, including 37 genetically and 31 neuropathologically proven cases. Diagnostic groups comprised patients with TDP-43 proteinopathy ALS, 4R tauopathy progressive supranuclear palsy, behavior variant FTD (bvFTD) as a group with either tau or TDP-43 pathology, and healthy controls. EV tau ratios were low in progressive supranuclear palsy and high in bvFTD with tau pathology. EV TDP-43 levels were high in ALS and in bvFTD with TDP-43 pathology. Both markers discriminated between the diagnostic groups with area under the curve values &gt;0.9, and between TDP-43 and tau pathology in bvFTD. Both markers strongly correlated with neurodegeneration, and clinical and neuropsychological markers of disease severity. Findings were replicated in an independent validation cohort of 292 patients including 34 genetically confirmed cases. Taken together, the combination of EV TDP-43 levels and EV 3R/4R tau ratios may aid the molecular diagnosis of FTD, FTD spectrum disorders and ALS, providing a potential biomarker to monitor disease progression and target engagement in clinical trials.</p

Search for dark matter produced in association with bottom or top quarks in √s = 13 TeV pp collisions with the ATLAS detector

A search for weakly interacting massive particle dark matter produced in association with bottom or top quarks is presented. Final states containing third-generation quarks and miss- ing transverse momentum are considered. The analysis uses 36.1 fb−1 of proton–proton collision data recorded by the ATLAS experiment at √s = 13 TeV in 2015 and 2016. No significant excess of events above the estimated backgrounds is observed. The results are in- terpreted in the framework of simplified models of spin-0 dark-matter mediators. For colour- neutral spin-0 mediators produced in association with top quarks and decaying into a pair of dark-matter particles, mediator masses below 50 GeV are excluded assuming a dark-matter candidate mass of 1 GeV and unitary couplings. For scalar and pseudoscalar mediators produced in association with bottom quarks, the search sets limits on the production cross- section of 300 times the predicted rate for mediators with masses between 10 and 50 GeV and assuming a dark-matter mass of 1 GeV and unitary coupling. Constraints on colour- charged scalar simplified models are also presented. Assuming a dark-matter particle mass of 35 GeV, mediator particles with mass below 1.1 TeV are excluded for couplings yielding a dark-matter relic density consistent with measurements

Research and Design of a Routing Protocol in Large-Scale Wireless Sensor Networks

无线传感器网络，作为全球未来十大技术之一，集成了传感器技术、嵌入式计算技术、分布式信息处理和自组织网技术，可实时感知、采集、处理、传输网络分布区域内的各种信息数据，在军事国防、生物医疗、环境监测、抢险救灾、防恐反恐、危险区域远程控制等领域具有十分广阔的应用前景。 本文研究分析了无线传感器网络的已有路由协议，并针对大规模的无线传感器网络设计了一种树状路由协议，它根据节点地址信息来形成路由，从而简化了复杂繁冗的路由表查找和维护，节省了不必要的开销，提高了路由效率，实现了快速有效的数据传输。 为支持此路由协议本文提出了一种自适应动态地址分配算——ADAR（AdaptiveDynamicAddre...As one of the ten high technologies in the future, wireless sensor network, which is the integration of micro-sensors, embedded computing, modern network and Ad Hoc technologies, can apperceive, collect, process and transmit various information data within the region. It can be used in military defense, biomedical, environmental monitoring, disaster relief, counter-terrorism, remote control of haz...学位：工学硕士院系专业：信息科学与技术学院通信工程系_通信与信息系统学号：2332007115216