Xiamen University Institutional Repository

    基于CHAID算法的病毒性肝炎患者DRGs分组研究

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    目的了解影响患者住院医疗费用的因素,建立drgS病例分组并对各组医疗费用进行分析评价。方法以厦门地区病毒性肝炎患者为研究对象,首先利用单因素和多因素方法分析患者住院医疗费用的影响因素,然后以患者住院医疗费用作为目标变量,通过CHAId模型进行drgS病例分组,最后采用rIV、CV等评价指标分析和评价分组结果。结果对可能影响住院医疗费用的变量进行单因素分析显示,年龄、付费方式、入院情况和是否手术4个因素具有统计学意义,通过多因素分析显示年龄、费用支付方式、入院情况是厦门地区肝炎患者住院费用的主要影响因素;进一步使用决策树CHAId模型分组得到3组该疾病的drgS病例组合,第一组为自费方式的患者,第二组为具有医疗保险且入院情况为一般的患者,第三组为具有医疗保险且入院情况为紧急的患者。经非参数kruSkAl-WAllIS H检验、rIV值、变异系数评价,该病例组合方案具有较好的可靠性和合理性。各病例分组的标准费用分别为1984.73元、1359.23元与1874.68元。分析每个分组的费用门坎值,发现线外病人比例为6.47%~7.65%,却消耗了23.07%-30.09%的医疗费用。结论通过drgS分组计算患者住院费用标准值可提供医疗保险机构的偿付参考值,自费病人的标准费用最高,其次是具有医疗保险且入院情况为紧急的患者,线外病人及其医疗消费应作为住院医疗费用总量控制重点。国家自然科学基金青年项目(71403229); 教育部人文社会科学研究项目资助(12YJA790030); 福建省自然科学基金资助项目(2013J05108

    Corrosion environment evaluation and durability design requirements of coastal concrete bridge

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    依据JTg/T b07—01—2006《公路工程混凝土结构防腐技术规范》和gb/T 50476—2008《混凝土结构耐久性设计规范》,结合海南一个沿海混凝土大桥的具体环境条件和工程结构情况,对大桥所处腐蚀环境评价中环境分区、环境作用分级以及耐久性设计要求等问题进行了研究。大桥的环境作用分为一般环境、土中环境、海洋环境和滨海环境四个区域。一般环境处于海南东北部沿海腐蚀偏高范围,腐蚀性较高,分级提高加以考虑。土中环境主要由于砖红壤地质腐蚀加重的影响,在工程详细勘探和耐久性设计时给于关注。海洋环境由于海南炎热地区水温高、盐度高会加重腐蚀,耐久性设计中给于考虑。滨海环境主要考虑海洋大气影响范围扩大、影响程度增高、海水入侵和盐渍化影响会不断扩大范围和程度等,对滨海大气和滨海土壤环境的耐久性加以重视。在大桥的设计、施工的不同阶段贯彻和实施规范的技术措施是保证耐久性的关键,对特殊形式和部位的构件和结构耐久性要给于专门措施。According to JTG/T B07—01—2006"Specification for deterioration prevention of highway concrete structures"and GB/T 50476—2008"Code for durability design of concrete structures",The corrosion environmental classification,environmental action grade and durability design requirements of a coastal concrete bridge in Hainan province are researched combining the bridge environment condition and engineering structure.The environment condition of the bridge is divided into four districts:the general environment,soil environment,ocean environment and coastal environment.The general environment is placed in northeast coast of Hainan and belongs to higher corrosion scope.The corrosion is higher so the grade is exalted.The influence in soil environment mainly is the Latosols geology corrosion.at the detailed investigation and design this must pay attention.because of in the south blazing hot region,the water temperature is high and the salt degree is high so the ocean environment will aggravate corrosion,the durability design must considered.The coastal environment mainly considers the ocean atmosphere spread,increasing corrosion degree,the sea water invading and salinization.The durability of the coastal atmosphere and coastal soil environment should be attached importance to.At the different stage of bridge design and construction the specialized technique measure is the key that promises durability.The special form and the part of bridge must carry out the specialized measure

    The influence of the electrical boundary condition on domain structures and electrocaloric effect of PbTiO3 nanostructures

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    本文在基于金兹堡—朗道—德文希尔唯象理论的相场法理论下,应用有限差分方法及四阶龙格—库塔法数值求解,研究不同电学边界条件对铁电纳米点畴结构演化和热电温度效应的影响。本文所用的中间电学边界条件,可以用来表示表面电极与纳米点之间的黏合情况及电极对表面电荷的补偿情况,进而说明退极化电场和退极化电能对系统自由能的影响,不同以往的对退极化能进行权重处理,具有实际的物理意义。 当电学参数λ0为0时,中间电学边界可以退化为开路电学边界条件;当λ0趋向无穷大时,对应于短路电学边界条件,即表面电荷可充分补偿。λ0的值越大,表明表面电荷部分补偿的程度越大,退极化电场能减小得越多。数值计算纳米PbTiO3(PTO...Phase field method based on Ginzburg-Landau-Devonshire theory is applied to study the evolution of domain structures and electrocaloric effect (ECE) of ferroelectric nanoparticles. The phase field equations are numerically solved by finite difference method and four-order Runge-Kutta method. Two-dimensional simulations of PbTiO3 (PTO) nanostructures are performed under the intermediate (IM) electr...学位:工学硕士院系专业:材料学院_材料学学号:2072013115006

    Photogenerated Cathodic Protection Properties Based on Micro-nano ZnO/TiO2 Composite Films

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    金属腐蚀问题给人们生活带来不便,且造成巨大的经济损失。传统金属防腐蚀方法均存在一定的缺陷。因此开发低能耗、环境友好型的金属防腐蚀技术具有重要的科研及应用意义。基于微纳米ZnO、TiO2优异光电化学性能的新型防腐技术--光生阴极保护技术已引起人们的广泛关注。但ZnO、TiO2只能吸收紫外光,光生载流子易复合,且暗态下难以持续对金属进行阴极保护。因此,本文采用工艺操作简便、常压低温条件下的湿化学方法制备ZnO阵列及对其进行TiO2、Fe-TiO2复合薄膜修饰耦合,并通过光电化学测试技术研究微纳结构复合阵列薄膜光阳极对304不锈钢的光生阴极保护性能。主要研究内容及结果如下: 1. 采用电化学沉积技...Metal corrosion problems bring inconvenience to people's life, and also can cause huge economic losses. All the traditional methods of anti-corrosion for metal have some defects. Therefore, the development of low energy consumption, environment-friendly anti-corrosion technology for metals has important scientific and practical application significance. Based on the excellent photoelectric chemica...学位:工学博士院系专业:材料学院_材料物理与化学学号:2072011015348

    Study on Preparation and Application of Adhesive for Polyolefin Film

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    由于具有较高的机械强度、良好的化学稳定性、较好的电绝缘性、优良的加工性等优势,聚烯烃塑料广泛应用于社会生活中。在众多的聚烯烃塑料制品中,最为常见的产品是薄膜制品,包括聚乙烯薄膜、聚丙烯薄膜、多层共挤聚烯烃薄膜等。为了获得更优异的性能,实际应用中一般将聚烯烃薄膜与自身或者其他薄膜(如铝箔、聚酰胺薄膜、聚酯薄膜等)进行复合使用。目前,在复合过程中常用的聚烯烃薄膜粘结剂存在以下两个问题:1、环保问题:目前国内广泛使用的酯溶型聚氨酯粘结剂可能含有异氰酸酯单体的残留,而水性粘结剂由于干燥速度慢、粘结强度低等先天缺陷,适用面较为狭窄。2、粘结强度不高:目前在市面上出售的聚烯烃粘结剂提供的T型剥离强度大多在...Because of the advantages of high mechanical strength, good chemical stability, strong electrical insulation, excellent processability, polyolefin plastics are widely used in many aspects of social life. In numerous polyolefin plastic products, the most common product is film, such as polyethylene film, polypropylene film, multi-layer co-extrusion polyolefin film etc. In order to achieve more exce...学位:工程硕士院系专业:材料学院_工程硕士(材料工程)学号:X201219303

    Modified Epoxy Resins by POSS-Based Copolymers Containing Phosphorus

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    高度交联的固化网络结构使得环氧树脂制品的质地较脆;与大多数高分子材料一样,环氧树脂主要组成元素为C、H、O,属于可燃材料。韧性和阻燃性能的不足限制了它更为广阔的用途。POSS是单纳米尺度的有机/无机杂化分子,它能够纳米增强基体树脂,无机的Si—O—Si结构可提高基体的热性能。磷、硅协同阻燃因高效、无卤、环保而备受研究者重视。本文合成了POSS基含磷无规共聚物P(MAiBuPOSS-co-HEP-co-HEMA),并用于改性环氧树脂;合成了POSS基含磷嵌段共聚物PMAiBuPOSS-b-PHEPO,并用于纳米构筑环氧树脂。 1.通过调节单体的投料比合成了不同Si、P元素含量的三元无规共聚物P...Epoxy resins (EP) which has excellent performances is one of the most widely used thermoset polymers. However, as a consequence of highly cross-linked network structure, its products have the drawback of brittleness; the same as most polymer materials, epoxy resins which consists mainly of carbon, hydrogen and oxygen atoms possess high flammable. The more extended applications of EP is limited by ...学位:工程硕士院系专业:材料学院_工程硕士(材料工程)学号:2072013115009

    Preparation, Properties and Applications of Bi2O3-Rich Lead-Free Sealing Glass Ceramics

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    本研究对富含Bi2O3无铅微晶封接玻璃的制备、性能和应用进行了研究;分别利用傅立叶转变红外分析测试仪(FTIR)、拉曼光谱分析仪、X-射线衍射分析仪(XRD)、示差扫描量热分析仪(DSC)、热膨胀系数仪(DIL)和超高电阻测试仪等分别对该封接玻璃的结构、析晶、玻璃化转变温度(Tg)、玻璃软化温度(Tf)、热膨胀系数(α)和电阻率(ρ)等进行研究。 本文理论研究方面,包含下述3项内容。其中,在第(二)项和第(三)项中特别研究了采用“模压成型—热处理方法”制备的样品过程中,热处理温度对其Tg、Tf、α和ρ等的影响。 (一)研究了B2O3在ZnO—Bi2O3—B2O3系统无铅微晶封接玻璃(ZBB...The preparation, properties and applications of Bi2O3-rich lead-free sealing glass-ceramics has been deeply discussed in this investigation. Fourier transform infrared spectroscopy (FTIR), Raman spectroscopy, differential scanning calorimetry (DSC), X-ray diffraction (XRD), dilatometer (DIL) and resistance measuring devices are used to study the performance of the sealing glass. The performance in...学位:工学硕士院系专业:材料学院_材料物理与化学学号:2072009115002

    Controllable Synthesis and Application of the Nickel-based Multi-element Nanocomposites for Lithium-ion Batteries

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    针对日渐匮乏的不可再生资源,科研工作者们致力于开发和探索洁净、环保的可再生资源,并也开始寻求提高能源转换和存储的有效方法。作为具有能量密度高、循环寿命长、安全性能好等诸多优点的新型储能器件,锂离子电池从一出现就受到了使用者的追捧。由于资源丰富、环境友好、理论容量高等优点,过渡金属氧化物被认为是最具有发展潜力的新一代锂离子电池电极材料之一。金属有机框架(MOFs)是一种拥有高的比表面积和孔隙率,且形态和结构可调控的优良材料,被认为是合成负极材料的理想前驱体。本论文采用金属有机框架作为前驱体,成功合成了ZnO/Ni3ZnC0.7/C和NiO/NiCo2O4两种纳米复合材料体系,并对其形貌、微结构以...In the face of increasingly scarce non-renewable resources, scientific researchers are committed to exploring the clean and environment friendly renewable energy. At the same time, they also began to seek the effective methods to improve energy conversion and storage. As one new kind of energy storage devices with many superiorities (such as high energy density, long cycle life, good safety perfor...学位:工学硕士院系专业:材料学院_工程硕士(材料工程)学号:2072013115011

    Methotrexate Nanoparticles: Synthesis, Characterization, and in Vitro and in Vivo Antitumoral Activity

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    癌症纳米疗法的迅速发展,解决了传统药物递送系统的选择性低、毒性大和耐药性等问题。研究高效的纳米靶向制剂是解决这些问题的关键课题,已受到生物医学及材料科学研究者的极大关注和兴趣。而肿瘤生长分子机制的揭示,发现肿瘤细胞与正常细胞的结构差异性,使得肿瘤细胞特有的分子靶点成为抗肿瘤药物研究和开发的热点。 本论文以提高药物的靶向性和延长其在血液中的循环时间为研究目的,制备了以壳聚糖(Chitosan,CS)和甲氧基聚乙二醇(Methoxypolyethyleneglycol,mPEG)为载体的甲氨蝶呤(Methotrexate,MTX))纳米靶向缓释系统,并研究其在体内外抗肿瘤作用。首先,对该MTX纳...Cancer nanotherapeutics are rapidly progressing and being put in place to solve several limitations of conventional drug delivery systems. With the rapid development of materials science, cell biology and molecular biology, targeted agents have grown up to be an important research content on the field of biomedical. Furthermore, as the revealing of the molecular mechanism of tumor growth, which th...学位:工学博士院系专业:材料学院_材料物理与化学学号:2072012015330

    Construction of Controlled Drug Release System based on Photothermal Conversion Property of Polypyrrole

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    聚吡咯(PPy)是一种有机导电聚合物,利用其优异的导电性、生物相容性以及较强的机械性能,可用作药物载体,并用电控制药物释放。此外,聚吡咯还具有较强的近红外吸收和理想的光热转换能力,聚吡咯纳米粒子(PPyNPs)的光热转化效率可达44.7%。结合这些优异性能,可实现聚吡咯材料在药物输送、生物传感及光热治疗等多个领域的应用。 本论文利用聚吡咯的光热转换性质,构建了两类基于近红外激光触发释药的药物释放体系: (1)月桂酸和聚乳酸复合的药物载体点阵,点阵中每一个点由两部分组成,包括内层药物核心和外部保护层。保护层由月桂酸、聚乳酸和聚吡咯纳米粒子构成。聚吡咯纳米粒子具有优异的光热转换能力,近红外光照...Polypyrrole (PPy) as an organic conductive polymer, due to excellent electrical conductivity, biocompatibility and strong mechanical properties, PPy can be used as drug carrier, and controlled drug release by electrical stimulation. In addition, PPy also has strong near-infrared absorption and ideal photothermal conversion capability, the photothermal conversion efficiency of PPy nanoparticles up ...学位:理学硕士院系专业:材料学院_生物医学工程学号:3142013115013
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