1,661 research outputs found
Creencias de estudiantes de educación física para enseñanza del deporte
The objective of this study was to analyze the beliefs of undergraduates about the strategies for teaching sports at the beginning of their Bachelors degree in Physical Education at a public university in Southern Brazil. A qualitative, descriptive and interpretive research approach was adopted through multiple case studies. Eight bachelor students in Physical Education participated in the study. To collect the data, we used a combination of structured and semi-structured interview procedures, systematic observation, and memory stimulation. Content analysis was used from categories determined a priori. The results indicated that the students have beliefs that favor strategies focused on analytical learning tasks, verbal management interventions, prescriptive pedagogical feedbacks, and positive evaluations. These beliefs were developed mainly through personal practical experiences in competitive sports as well as through observation of coaches or teachers and verbal orientations received from coaches and peers. The undergraduates’ beliefs about teaching strategies represent a particular conceptual model, with structures similar to directive teaching models. Thus, we conclude that the prolonged contact of the undergraduates with various learning situations in sports contributed to the memorization of concepts, values, and teaching behaviors, which enabled and conditioned the construction of one own model of teaching sports.El objetivo de este estudio fue analizar las creencias de los estudiantes de Educación Física de una universidad pública brasileña, acerca de las estrategias para la enseñanza de los deportes. Se realizó una investigación cualitativa, descriptiva e interpretativa con procedimientos de estudio de casos múltiplos de ocho estudiantes de licenciatura en Educación Física. Los datos fueron obtenidos por medio de la combinación de procedimientos de entrevista, observación sistemática y estimulación de la memoria. Para el análisis de contenido se utilizó categorías determinadas a priori. Los resultados indicaron que los estudiantes presentaron creencias que favorecen estrategias enfocadas en tareas analíticas de aprendizaje, intervenciones verbales de manejo de clase, feedbacks pedagógicos prescriptivos y evaluativos positivos. Estas creencias se desarrollaron a través de experiencias prácticas personales en deportes competitivos, la observación de entrenadores o maestros, y en las orientaciones verbales recibidas de entrenadores y compañeros. Las creencias de los estudiantes retratan un modelo conceptual particular, con estructuras similares a los modelos de enseñanza directiva. Se concluyó que el contacto prolongado de los estudiantes en situaciones de aprendizaje en los deportes contribuyó a la memorización de conceptos, valores y comportamientos de enseñanza, condicionando la construcción de su modelo personal de enseñanza de los deportes.Facultad de Humanidades y Ciencias de la Educació
Creencias de estudiantes de educación física para enseñanza del deporte
The objective of this study was to analyze the beliefs of undergraduates about the strategies for teaching sports at the beginning of their Bachelors degree in Physical Education at a public university in Southern Brazil. A qualitative, descriptive and interpretive research approach was adopted through multiple case studies. Eight bachelor students in Physical Education participated in the study. To collect the data, we used a combination of structured and semi-structured interview procedures, systematic observation, and memory stimulation. Content analysis was used from categories determined a priori. The results indicated that the students have beliefs that favor strategies focused on analytical learning tasks, verbal management interventions, prescriptive pedagogical feedbacks, and positive evaluations. These beliefs were developed mainly through personal practical experiences in competitive sports as well as through observation of coaches or teachers and verbal orientations received from coaches and peers. The undergraduates’ beliefs about teaching strategies represent a particular conceptual model, with structures similar to directive teaching models. Thus, we conclude that the prolonged contact of the undergraduates with various learning situations in sports contributed to the memorization of concepts, values, and teaching behaviors, which enabled and conditioned the construction of one own model of teaching sports.El objetivo de este estudio fue analizar las creencias de los estudiantes de Educación Física de una universidad pública brasileña, acerca de las estrategias para la enseñanza de los deportes. Se realizó una investigación cualitativa, descriptiva e interpretativa con procedimientos de estudio de casos múltiplos de ocho estudiantes de licenciatura en Educación Física. Los datos fueron obtenidos por medio de la combinación de procedimientos de entrevista, observación sistemática y estimulación de la memoria. Para el análisis de contenido se utilizó categorías determinadas a priori. Los resultados indicaron que los estudiantes presentaron creencias que favorecen estrategias enfocadas en tareas analíticas de aprendizaje, intervenciones verbales de manejo de clase, feedbacks pedagógicos prescriptivos y evaluativos positivos. Estas creencias se desarrollaron a través de experiencias prácticas personales en deportes competitivos, la observación de entrenadores o maestros, y en las orientaciones verbales recibidas de entrenadores y compañeros. Las creencias de los estudiantes retratan un modelo conceptual particular, con estructuras similares a los modelos de enseñanza directiva. Se concluyó que el contacto prolongado de los estudiantes en situaciones de aprendizaje en los deportes contribuyó a la memorización de conceptos, valores y comportamientos de enseñanza, condicionando la construcción de su modelo personal de enseñanza de los deportes.Facultad de Humanidades y Ciencias de la Educació
Reciclagem de materiais: estudo das propriedades mecânicas de policarbonato reciclado de discos compactos
Creencias de estudiantes de educación física para enseñanza del deporte
The objective of this study was to analyze the beliefs of undergraduates about the strategies for teaching sports at the beginning of their Bachelors degree in Physical Education at a public university in Southern Brazil. A qualitative, descriptive and interpretive research approach was adopted through multiple case studies. Eight bachelor students in Physical Education participated in the study. To collect the data, we used a combination of structured and semi-structured interview procedures, systematic observation, and memory stimulation. Content analysis was used from categories determined a priori. The results indicated that the students have beliefs that favor strategies focused on analytical learning tasks, verbal management interventions, prescriptive pedagogical feedbacks, and positive evaluations. These beliefs were developed mainly through personal practical experiences in competitive sports as well as through observation of coaches or teachers and verbal orientations received from coaches and peers. The undergraduates’ beliefs about teaching strategies represent a particular conceptual model, with structures similar to directive teaching models. Thus, we conclude that the prolonged contact of the undergraduates with various learning situations in sports contributed to the memorization of concepts, values, and teaching behaviors, which enabled and conditioned the construction of one own model of teaching sports.El objetivo de este estudio fue analizar las creencias de los estudiantes de Educación Física de una universidad pública brasileña, acerca de las estrategias para la enseñanza de los deportes. Se realizó una investigación cualitativa, descriptiva e interpretativa con procedimientos de estudio de casos múltiplos de ocho estudiantes de licenciatura en Educación Física. Los datos fueron obtenidos por medio de la combinación de procedimientos de entrevista, observación sistemática y estimulación de la memoria. Para el análisis de contenido se utilizó categorías determinadas a priori. Los resultados indicaron que los estudiantes presentaron creencias que favorecen estrategias enfocadas en tareas analíticas de aprendizaje, intervenciones verbales de manejo de clase, feedbacks pedagógicos prescriptivos y evaluativos positivos. Estas creencias se desarrollaron a través de experiencias prácticas personales en deportes competitivos, la observación de entrenadores o maestros, y en las orientaciones verbales recibidas de entrenadores y compañeros. Las creencias de los estudiantes retratan un modelo conceptual particular, con estructuras similares a los modelos de enseñanza directiva. Se concluyó que el contacto prolongado de los estudiantes en situaciones de aprendizaje en los deportes contribuyó a la memorización de conceptos, valores y comportamientos de enseñanza, condicionando la construcción de su modelo personal de enseñanza de los deportes.Facultad de Humanidades y Ciencias de la Educació
Rare germline variants in DNA repair genes and the angiogenesis pathway predispose prostate cancer patients to develop metastatic disease
Background
Prostate cancer (PrCa) demonstrates a heterogeneous clinical presentation ranging from largely indolent to lethal. We sought to identify a signature of rare inherited variants that distinguishes between these two extreme phenotypes.
Methods
We sequenced germline whole exomes from 139 aggressive (metastatic, age of diagnosis < 60) and 141 non-aggressive (low clinical grade, age of diagnosis ≥60) PrCa cases. We conducted rare variant association analyses at gene and gene set levels using SKAT and Bayesian risk index techniques. GO term enrichment analysis was performed for genes with the highest differential burden of rare disruptive variants.
Results
Protein truncating variants (PTVs) in specific DNA repair genes were significantly overrepresented among patients with the aggressive phenotype, with BRCA2, ATM and NBN the most frequently mutated genes. Differential burden of rare variants was identified between metastatic and non-aggressive cases for several genes implicated in angiogenesis, conferring both deleterious and protective effects.
Conclusions
Inherited PTVs in several DNA repair genes distinguish aggressive from non-aggressive PrCa cases. Furthermore, inherited variants in genes with roles in angiogenesis may be potential predictors for risk of metastases. If validated in a larger dataset, these findings have potential for future clinical application
First narrow-band search for continuous gravitational waves from known pulsars in advanced detector data
Spinning neutron stars asymmetric with respect to their rotation axis are potential sources of
continuous gravitational waves for ground-based interferometric detectors. In the case of known pulsars a
fully coherent search, based on matched filtering, which uses the position and rotational parameters
obtained from electromagnetic observations, can be carried out. Matched filtering maximizes the signalto-
noise (SNR) ratio, but a large sensitivity loss is expected in case of even a very small mismatch
between the assumed and the true signal parameters. For this reason, narrow-band analysis methods have
been developed, allowing a fully coherent search for gravitational waves from known pulsars over a
fraction of a hertz and several spin-down values. In this paper we describe a narrow-band search of
11 pulsars using data from Advanced LIGO’s first observing run. Although we have found several initial
outliers, further studies show no significant evidence for the presence of a gravitational wave signal.
Finally, we have placed upper limits on the signal strain amplitude lower than the spin-down limit for 5 of
the 11 targets over the bands searched; in the case of J1813-1749 the spin-down limit has been beaten for
the first time. For an additional 3 targets, the median upper limit across the search bands is below the
spin-down limit. This is the most sensitive narrow-band search for continuous gravitational waves carried
out so far
Measurement of χ c1 and χ c2 production with s√ = 7 TeV pp collisions at ATLAS
The prompt and non-prompt production cross-sections for the χ c1 and χ c2 charmonium states are measured in pp collisions at s√ = 7 TeV with the ATLAS detector at the LHC using 4.5 fb−1 of integrated luminosity. The χ c states are reconstructed through the radiative decay χ c → J/ψγ (with J/ψ → μ + μ −) where photons are reconstructed from γ → e + e − conversions. The production rate of the χ c2 state relative to the χ c1 state is measured for prompt and non-prompt χ c as a function of J/ψ transverse momentum. The prompt χ c cross-sections are combined with existing measurements of prompt J/ψ production to derive the fraction of prompt J/ψ produced in feed-down from χ c decays. The fractions of χ c1 and χ c2 produced in b-hadron decays are also measured
Measurements of fiducial and differential cross sections for Higgs boson production in the diphoton decay channel at s√=8 TeV with ATLAS
Measurements of fiducial and differential cross sections are presented for Higgs boson production in proton-proton collisions at a centre-of-mass energy of s√=8 TeV. The analysis is performed in the H → γγ decay channel using 20.3 fb−1 of data recorded by the ATLAS experiment at the CERN Large Hadron Collider. The signal is extracted using a fit to the diphoton invariant mass spectrum assuming that the width of the resonance is much smaller than the experimental resolution. The signal yields are corrected for the effects of detector inefficiency and resolution. The pp → H → γγ fiducial cross section is measured to be 43.2 ±9.4(stat.) − 2.9 + 3.2 (syst.) ±1.2(lumi)fb for a Higgs boson of mass 125.4GeV decaying to two isolated photons that have transverse momentum greater than 35% and 25% of the diphoton invariant mass and each with absolute pseudorapidity less than 2.37. Four additional fiducial cross sections and two cross-section limits are presented in phase space regions that test the theoretical modelling of different Higgs boson production mechanisms, or are sensitive to physics beyond the Standard Model. Differential cross sections are also presented, as a function of variables related to the diphoton kinematics and the jet activity produced in the Higgs boson events. The observed spectra are statistically limited but broadly in line with the theoretical expectations
Search for squarks and gluinos in events with isolated leptons, jets and missing transverse momentum at s√=8 TeV with the ATLAS detector
The results of a search for supersymmetry in final states containing at least one isolated lepton (electron or muon), jets and large missing transverse momentum with the ATLAS detector at the Large Hadron Collider are reported. The search is based on proton-proton collision data at a centre-of-mass energy s√=8 TeV collected in 2012, corresponding to an integrated luminosity of 20 fb−1. No significant excess above the Standard Model expectation is observed. Limits are set on supersymmetric particle masses for various supersymmetric models. Depending on the model, the search excludes gluino masses up to 1.32 TeV and squark masses up to 840 GeV. Limits are also set on the parameters of a minimal universal extra dimension model, excluding a compactification radius of 1/R c = 950 GeV for a cut-off scale times radius (ΛR c) of approximately 30
Measurement of the production of a W boson in association with a charm quark in pp collisions at √s = 7 TeV with the ATLAS detector
The production of a W boson in association with a single charm quark is studied using 4.6 fb−1 of pp collision data at s√ = 7 TeV collected with the ATLAS detector at the Large Hadron Collider. In events in which a W boson decays to an electron or muon, the charm quark is tagged either by its semileptonic decay to a muon or by the presence of a charmed meson. The integrated and differential cross sections as a function of the pseudorapidity of the lepton from the W-boson decay are measured. Results are compared to the predictions of next-to-leading-order QCD calculations obtained from various parton distribution function parameterisations. The ratio of the strange-to-down sea-quark distributions is determined to be 0.96+0.26−0.30 at Q 2 = 1.9 GeV2, which supports the hypothesis of an SU(3)-symmetric composition of the light-quark sea. Additionally, the cross-section ratio σ(W + +c¯¯)/σ(W − + c) is compared to the predictions obtained using parton distribution function parameterisations with different assumptions about the s−s¯¯¯ quark asymmetry
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