205 research outputs found
Familization risks, defamilization risks and older women
© 2019, © 2019 Taylor & Francis. This article is about the familization and defamilization risks faced by older women. Such risks are generated by the lack of one or both of two conditions: the freedom to choose whether or not to perform certain family roles; and the capacity to maintain a reasonable standard of living. Examples are drawn from findings of a qualitative study in Hong Kong, in which 40 older women aged 65 or above were interviewed to discuss their experiences of issues relating to the risks and their diverse preferences of how these issues should be handled
The CIPAZ study protocol: an open label randomised controlled trial of azithromycin versus ciprofloxacin for the treatment of children hospitalised with dysentery in Ho Chi Minh City, Vietnam
Background: Diarrhoeal disease remains a common cause of illness and death in children <5 years of age. Faecal-oral infection by Shigella spp. causing bacillary dysentery is a leading cause of moderate-to-severe diarrhoea, particularly in low and middle-income countries. In Southeast Asia, S. sonnei predominates and infections are frequently resistant to first-line treatment with the fluoroquinolone, ciprofloxacin. While resistance to all antimicrobials is increasing, there may be theoretical and clinical benefits to prioritizing treatment of bacillary dysentery with the azalide, azithromycin. In this study we aim to measure the efficacy of treatment with azithromycin compared with ciprofloxacin, the current standard of care, for the treatment of children with bacillary dysentery.
Methods and analysis: We will perform a multicentre, open-label, randomized controlled trial of two therapeutic options for the antimicrobial treatment of children hospitalised with dysentery. Children (6â60 months of age) presenting with symptoms and signs of dysentery at Childrenâs Hospital 2 in Ho Chi Minh City will be randomised (1:1) to treatment with either oral ciprofloxacin (15mg/kg/twice daily for 3 days, standard-of-care) or oral azithromycin (10mg/kg/daily for 3 days). The primary endpoint will be the proportion of treatment failure (defined by clinical and microbiological parameters) by day 28 (+3 days) and will be compared between study arms by logistic regression modelling using treatment allocation as the main variable.
Ethics and dissemination: The study protocol (version 1.2 dated 27th December 2018) has been approved by the Oxford Tropical Research Ethics Committee (47â18) and the ethical review boards of Children's Hospital 2 (1341/NÄ2-CÄT). The study has also been approved by the Vietnamese Ministry of Health (5044/QÄ-BYT).
Trial registration: Clinicaltrials.gov: NCT03854929 (February 26th 2019)
Pseudo-unitary symmetry and the Gaussian pseudo-unitary ensemble of random matrices
Employing the currently discussed notion of pseudo-Hermiticity, we define a
pseudo-unitary group. Further, we develop a random matrix theory which is
invariant under such a group and call this ensemble of pseudo-Hermitian random
matrices as the pseudo-unitary ensemble. We obtain exact results for the
nearest-neighbour level spacing distribution for (2 X 2) PT-symmetric
Hamiltonian matrices which has a novel form, s log (1/s) near zero spacing.
This shows a level repulsion in marked distinction with an algebraic form in
the Wigner surmise. We believe that this paves way for a description of varied
phenomena in two-dimensional statistical mechanics, quantum chromodynamics, and
so on.Comment: 9 pages, 2 figures, LaTeX, submitted to the Physical Review Letters
on August 20, 200
Recent glitches detected in the Crab pulsar
From 2000 to 2010, monitoring of radio emission from the Crab pulsar at
Xinjiang Observatory detected a total of nine glitches. The occurrence of
glitches appears to be a random process as described by previous researches. A
persistent change in pulse frequency and pulse frequency derivative after each
glitch was found. There is no obvious correlation between glitch sizes and the
time since last glitch. For these glitches and
span two orders of magnitude. The pulsar suffered the
largest frequency jump ever seen on MJD 53067.1. The size of the glitch is
6.8 Hz, 3.5 times that of the glitch occured in
1989 glitch, with a very large permanent changes in frequency and pulse
frequency derivative and followed by a decay with time constant 21 days.
The braking index presents significant changes. We attribute this variation to
a varying particle wind strength which may be caused by glitch activities. We
discuss the properties of detected glitches in Crab pulsar and compare them
with glitches in the Vela pulsar.Comment: Accepted for publication in Astrophysics & Space Scienc
Scoping review : intergenerational resource transfer and possible enabling factors
We explore the intergenerational pattern of resource transfer and possible associated factors. A scoping review was conducted of quantitative, peer-reviewed, English-language studies related to intergenerational transfer or interaction. We searched AgeLine, PsycINFO, Social Work Abstracts, and Sociological Abstracts for articles published between Jane 2008 and December 2018. Seventy-five studies from 25 countries met the inclusion criteria. The scoping review categorised resource transfers into three types: financial, instrumental, and emotional support. Using an intergenerational solidarity framework, factors associated with intergenerational transfer were placed in four categories: (1) demographic factors (e.g., age, gender, marital status, education, and ethno-cultural background); (2) needs and opportunities factors, including health, financial resources, and employment status; (3) family structures, namely, family composition, family relationship, and earlier family events; and (4) cultural-contextual structures, including state policies and social norms. Those factors were connected to the direction of resource transfer between generations. Downward transfers from senior to junior generations occur more frequently than upward transfers in many developed countries. Women dominate instrumental transfers, perhaps influenced by traditional gender roles. Overall, the pattern of resource transfer between generations is shown, and the impact of social norms and social policy on intergenerational transfers is highlighted. Policymakers should recognise the complicated interplay of each factor with different cultural contexts. The findings could inform policies that strengthen intergenerational solidarity and support.</jats:p
What Drives Fitness Apps Usage? An Empirical Evaluation
Part 3: Creating Value through ApplicationsInternational audienceThe increased health problems associated with lack of physical activity is of great concern around the world. Mobile phone based fitness applications appear to be a cost effective promising solution for this problem. The aim of this study is to develop a research model that can broaden understanding of the factors that influence the user acceptance of mobile fitness apps. Drawing from Unified Theory of Acceptance and Use of Technology (UTAUT) and Elaboration Likelihood Model (ELM), we conceptualize the antecedents and moderating factors of fitness app use. We validate our model using field survey. Implications for research and practice are discussed
Event reconstruction for KM3NeT/ORCA using convolutional neural networks
The authors acknowledge the financial support of the funding agencies: Agence Nationale de la Recherche (contract ANR-15-CE31-0020), Centre National de la Recherche Scientifique (CNRS), Commission Europeenne (FEDER fund and Marie Curie Program), Institut Universitaire de France (IUF), LabEx UnivEarthS (ANR-10-LABX-0023 and ANR-18-IDEX-0001), Paris Ile-de-France Region, France; Shota Rustaveli National Science Foundation of Georgia (SRNSFG, FR-18-1268), Georgia; Deutsche Forschungsgemeinschaft (DFG), Germany; The General Secretariat of Research and Technology (GSRT), Greece; Istituto Nazionale di Fisica Nucleare (INFN), Ministero dell'Universita e della Ricerca (MUR), PRIN 2017 program (Grant NAT-NET 2017W4HA7S) Italy; Ministry of Higher Education, Scientific Research and Professional Training, Morocco; Nederlandse organisatie voor Wetenschappelijk Onderzoek (NWO), the Netherlands; The National Science Centre, Poland (2015/18/E/ST2/00758); National Authority for Scientific Research (ANCS), Romania; Ministerio de Ciencia, Innovacion, Investigacion y Universidades (MCIU): Programa Estatal de Generacion de Conocimiento (refs. PGC2018-096663-B-C41, -A-C42, -B-C43, -B-C44) (MCIU/FEDER), Severo Ochoa Centre of Excellence and MultiDark Consolider (MCIU), Junta de Andalucia (ref. SOMM17/6104/UGR), Generalitat Valenciana: Grisolia (ref. GRISOLIA/2018/119) and GenT (ref. CIDEGENT/2018/034) programs, La Caixa Foundation (ref. LCF/BQ/IN17/11620019), EU: MSC program (ref. 713673), Spain.The KM3NeT research infrastructure is currently under construction at two locations in the Mediterranean Sea. The KM3NeT/ORCA water-Cherenkov neutrino detector off the French coast will instrument several megatons of seawater with photosensors. Its main objective is the determination of the neutrino mass ordering. This work aims at demonstrating the general applicability of deep convolutional neural networks to neutrino telescopes, using simulated datasets for the KM3NeT/ORCA detector as an example. To this end, the networks are employed to achieve reconstruction and classification tasks that constitute an alternative to the analysis pipeline presented for KM3NeT/ORCA in the KM3NeT Letter of Intent. They are used to infer event reconstruction estimates for the energy, the direction, and the interaction point of incident neutrinos. The spatial distribution of Cherenkov light generated by charged particles induced in neutrino interactions is classified as shower- or track-like, and the main background processes associated with the detection of atmospheric neutrinos are recognized. Performance comparisons to machine-learning classification and maximum-likelihood reconstruction algorithms previously developed for KM3NeT/ORCA are provided. It is shown that this application of deep convolutional neural networks to simulated datasets for a large-volume neutrino telescope yields competitive reconstruction results and performance improvements with respect to classical approaches.French National Research Agency (ANR)
ANR-15-CE31-0020Centre National de la Recherche Scientifique (CNRS), Commission Europeenne (FEDER fund)European Union (EU)Institut Universitaire de France (IUF)LabEx UnivEarthS
ANR-10-LABX-0023
ANR-18-IDEX-0001Shota Rustaveli National Science Foundation of Georgia
FR-18-1268German Research Foundation (DFG)Greek Ministry of Development-GSRTIstituto Nazionale di Fisica Nucleare (INFN)Ministry of Education, Universities and Research (MIUR)
Research Projects of National Relevance (PRIN)Ministry of Higher Education, Scientific Research and Professional Training, MoroccoNetherlands Organization for Scientific Research (NWO)National Science Centre, Poland
2015/18/E/ST2/00758National Authority for Scientific Research (ANCS), RomaniaMinisterio de Ciencia, Innovacion, Investigacion y Universidades
PGC2018-096663-B-C41
A-C42
B-C43
B-C44Severo Ochoa Centre of ExcellenceJunta de Andalucia
SOMM17/6104/UGRGeneralitat Valenciana: Grisolia
GRISOLIA/2018/119
CIDEGENT/2018/034La Caixa Foundation
LCF/BQ/IN17/11620019EU: MSC program
71367
gSeaGen: The KM3NeT GENIE-based code for neutrino telescopes
Program summary
Program Title: gSeaGen
CPC Library link to program files: http://dx.doi.org/10.17632/ymgxvy2br4.1
Licensing provisions: GPLv3
Programming language: C++
External routines/libraries: GENIE [1] and its external dependencies. Linkable to MUSIC [2] and PROPOSAL
[3].
Nature of problem: Development of a code to generate detectable events in neutrino telescopes, using
modern and maintained neutrino interaction simulation libraries which include the state-of-the-art
physics models. The default application is the simulation of neutrino interactions within KM3NeT [4].
Solution method: Neutrino interactions are simulated using GENIE, a modern framework for Monte
Carlo event generators. The GENIE framework, used by nearly all modern neutrino experiments, is
considered as a reference code within the neutrino community.
Additional comments including restrictions and unusual features: The code was tested with GENIE version
2.12.10 and it is linkable with release series 3. Presently valid up to 5 TeV. This limitation is not intrinsic
to the code but due to the present GENIE valid energy range.
References:
[1] C. Andreopoulos at al., Nucl. Instrum. Meth. A614 (2010) 87.
[2] P. Antonioli et al., Astropart. Phys. 7 (1997) 357.
[3] J. H. Koehne et al., Comput. Phys. Commun. 184 (2013) 2070.
[4] S. AdriĂĄn-MartĂnez et al., J. Phys. G: Nucl. Part. Phys. 43 (2016) 084001.The gSeaGen code is a GENIE-based application developed to efficiently generate high statistics samples
of events, induced by neutrino interactions, detectable in a neutrino telescope. The gSeaGen code is able
to generate events induced by all neutrino flavours, considering topological differences between tracktype
and shower-like events. Neutrino interactions are simulated taking into account the density and
the composition of the media surrounding the detector. The main features of gSeaGen are presented
together with some examples of its application within the KM3NeT project.French National Research Agency (ANR)
ANR-15-CE31-0020Centre National de la Recherche Scientifique (CNRS)European Union (EU)Institut Universitaire de France (IUF), FranceIdEx program, FranceUnivEarthS Labex program at Sorbonne Paris Cite
ANR-10-LABX-0023
ANR-11-IDEX-000502Paris Ile-de-France Region, FranceShota Rustaveli National Science Foundation of Georgia (SRNSFG), Georgia
FR-18-1268German Research Foundation (DFG)Greek Ministry of Development-GSRTIstituto Nazionale di Fisica Nucleare (INFN)Ministry of Education, Universities and Research (MIUR)PRIN 2017 program Italy
NAT-NET 2017W4HA7SMinistry of Higher Education, Scientific Research and Professional Training, MoroccoNetherlands Organization for Scientific Research (NWO)
Netherlands GovernmentNational Science Centre, Poland
2015/18/E/ST2/00758National Authority for Scientific Research (ANCS), RomaniaMinisterio de Ciencia, Innovacion, Investigacion y Universidades (MCIU): Programa Estatal de Generacion de Conocimiento, Spain (MCIU/FEDER)
PGC2018-096663-B-C41
PGC2018-096663-A-C42
PGC2018-096663-BC43
PGC2018-096663-B-C44Severo Ochoa Centre of Excellence and MultiDark Consolider (MCIU), Junta de Andalucia, Spain
SOMM17/6104/UGRGeneralitat Valenciana: Grisolia, Spain
GRISOLIA/2018/119GenT, Spain
CIDEGENT/2018/034La Caixa Foundation
LCF/BQ/IN17/11620019EU: MSC program, Spain
71367
Measurement of the cross section of high transverse momentum ZâbbÌ production in protonâproton collisions at âs = 8 TeV with the ATLAS detector
This Letter reports the observation of a high transverse momentum ZâbbÌ signal in protonâproton collisions at âs=8 TeV and the measurement of its production cross section. The data analysed were collected in 2012 with the ATLAS detector at the LHC and correspond to an integrated luminosity of 19.5 fbâÂč. The ZâbbÌ decay is reconstructed from a pair of b -tagged jets, clustered with the anti-ktkt jet algorithm with R=0.4R=0.4, that have low angular separation and form a dijet with pT>200 GeVpT>200 GeV. The signal yield is extracted from a fit to the dijet invariant mass distribution, with the dominant, multi-jet background mass shape estimated by employing a fully data-driven technique that reduces the dependence of the analysis on simulation. The fiducial cross section is determined to be
ÏZâbbÂŻfid=2.02±0.20 (stat.) ±0.25 (syst.)±0.06 (lumi.) pb=2.02±0.33 pb,
in good agreement with next-to-leading-order theoretical predictions
- âŠ