114 research outputs found
FENOLOGIA E GERMINAÇÃO DE SEMENTES DE AGUAI, Chrysophyllum gonocarpum (Mart. & Eichl.) Engl.
- Publication venue
- 'Universidade Federal do Parana'
- Publication date
- 30/06/2008
- Field of study
Basic information on Chrysophyllum gonocarpum, Sapotaceae, still is incipient, therefore, this study intends to contribute with phenology, morphologic and germination registers. Comments and collection of botanical material had been carried out in the Region of the High Medium Uruguay and Missions (RS), from September/2004 to November/2005, as well as the physical and germination tests in laboratory. The species iniates flowers and blooms from September to December and the fruits from May to November. The inflorescence is constituted by groups of small flowers white-greenish with imbricate prebudding, being the metachlamydae, actinomorphic, pentamerous flower, with, upper syncarpus gymnoecium, anthers extrorse, distinct usuably dithecal opening by longitudinal slits, dorsifixix and axillary placentation. The fruit is a quadrangular berry of yellow colour, smooth surface, fleshy mesocarp and endocarp; from 1 to 5 seeds, luniformin moon form half with tegument of brown colour, bright thin pulp, with visible linear scar. The embryo posses two great large foliaceous cotyledons, hipocotylilo short and thick, endosperm uniform, surrounding the embryo. The germination is epigeal and the and seedling is phanerocotylar. The weight of 1,000 seeds is 381g with 2,625 units per kg, with humidity of 47.16%. The results pointed out that the germination is slow desuniforme and therefore there is need for more studies to accelerate, uniform or even establish the germination.Informações básicas sobre Chrysophyllum gonocarpum (Mart. & Eichl.) Engl., Sapotaceae, ainda são incipientes. Assim, pretende-se contribuir com dados fenológicos, morfológicos e germinativos sobre essa espécie. As observações e a coleta de material botânico foram realizadas na região do Médio Alto Uruguai e das Missões (RS), de setembro de 2004 a novembro de 2005, e os testes físicos e germinativos em laboratório. A espécie floresce de setembro a dezembro, e frutifica de maio a novembro. A inflorescência é constituída por grupos de pequenas flores branco-esverdeadas com prefloração imbricada, sendo a flor metaclamídea, actinomorfa, pentâmera, com gineceu sincárpico, súpero, anteras extrorsas, rimosas, dorsifixas e placentação axilar. O fruto é uma baga quadrangular, com epicarpo liso, de cor amarela, de mesocarpo e endocarpo carnoso macio, ovário com 1 a 5 sementes em forma de meia lua, tegumento lustroso, de cor castanha, com cicatriz linear visível. O embrião possui dois cotilédones grandes, foliáceos, hipocótilo curto e espesso, endosperma uniforme, circundando o embrião. A germinação é epígea e a plântula é caracterizada como fanerocotiledonar. Na análise física, o peso de 1000 sementes foi de 381 g, contabilizando 2.625 unidades por quilo, com umidade de 47,16%. Quanto à germinação, os resultados obtidos apontaram para um processo lento e desuniforme, demonstrando, portanto, a necessidade de maiores estudos para acelerar, uniformizar ou até mesmo estabelecer a germinação
Histopathological study on biopsy track in malignant musculoskeletal tumors
- Author
- Publication venue
- Atha Comunicação & Editora
- Publication date
- 01/01/2009
- Field of study
OBJETIVO: Verificar se havia risco de contaminação por células neoplásicas no trajeto da biópsia e estudar as alterações histológicas locais. MÉTODOS: Realizou-se um estudo prospectivo com trajetos de biópsias de pacientes operados por tumores musculoesqueléticos malignos no Instituto de Ortopedia e Traumatologia da Faculdade de Medicina da Universidade de São Paulo no período de abril de 2006 a abril de 2007. Foram estudados por histopatologia 25 casos. RESULTADOS: Houve implante de células neoplásicas em 32% dos trajetos. As alterações histológicas mais comuns nos casos positivos foram classificadas como: fibrose acentuada, componente inflamatório leve e neovascularização acentuada. CONCLUSÃO: Sugerimos a ressecção tradicional oncológica do trajeto junto com a peça.OBJECTIVE: To investigate whether there is any risk of seeding by neoplasic cells along biopsy tracks and to study local histological abnormalities. METHODS: This was a prospective study on biopsy tracks in patients who underwent operations due to malignant musculoskeletal tumors between April 2006 and April 2007. RESULTS: Neoplasic cell implantation occurred in 32% of the tracks. The most common histological abnormalities in positive cases were classified as severe fibrosis, mild inflammatory component and severe neovascularization. CONCLUSION: We suggest that traditional oncological resection of the track should be carried out together with excision of the specimen
Expression profiles of eNOS, iNOS and microRNA-27b in the corpus cavernosum of rats submitted to chronic alcoholism and Diabetes mellitus
- Author
- Andersson KE
- Ayta IA
- Braun M
- Burnett AL
- Burnett AL
- Burnett AL
- Burnett AL
- Camila Albuquerque Mello de Carvalho
- Carlos Augusto Fernandes Molina
- Cirino G
- Daniela Gattas
- Daniela Pretti da Cunha Tirapelli
- Derogatis LR
- Fermino Sanches Lizarte Neto
- Holmquist F
- Joao Paulo da Cunha
- Kim N
- Lizarte FS
- Lizarte FS
- Luis Fernando Tirapelli
- Martin-Morales A
- Mersdorf A
- Michal V
- Paulo Cezar Novais
- Saito M
- Selvin E
- Silvio Tucci Junior
- Staszel T
- Sáenz de Tejada I
- Tirapelli CR
- Trigo-Rocha F
- Troncale JA
- Urbich C
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
Estudo histopatológico do trajeto de biópsia de tumores musculoesqueléticos malignos
- Author
- André Mathias Baptista
- Camargo OP
- Carlos Fernando Saito
- Chojniak R
- Cláudia Regina G.C.M. de Oliveira
- David A
- Davies NM
- De Santos LA
- Enneking WF
- Ginaldi S
- Gonçalves JC
- Jesus-Garcia R
- Mankin HJ
- Marcelo Barbosa Ribeiro
- Marcelo Tadeu Caiero
- Olavo Pires de Camargo
- Pollock RC
- Renée Zon Filippi
- Schwartz HS
- Simon MA
- Stoker DJ
- Sérgio Antonio Barbosa do Nascimento
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- 01/01/2009
- Field of study
A correlação entre exames de imagem, características anatomopatológicas e imunoistoquímicas num caso de tumor de céculas gigantes e agressivo do osso, com localização em coluna
- Author
- Carlos Fernando Saito
- Chakravarti A
- Claudia Regina Gomes Cardim Mendes de Oliveira
- Denise A. A. Mello Lula
- DeSouza PE
- Ghert MA
- Jaffe HL
- Komiya S
- Levine AJ
- Maria Claudia Nogueira Zerbini
- Masui F
- Mc Donald DJ
- Mousses S
- Olavo Pires de Camargo
- Present D
- Renée Zon Filippi
- Roberto Basile
- Sanjay BK
- Shikata J
- Sovini R
- Sérgio Antonio Barbosa do Nascimento
- Unni HK
- Wulling M
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- 01/01/2006
- Field of study
Impact of COVID-19 on cardiovascular testing in the United States versus the rest of the world
- Author
- Abad Pedro
- Abbara Suhny
- Abbasi Taimur
- Abbott Brian
- Abdel Aziz Islam Shawky
- Abdulla Jawdat
- Abikhzer Gad
- Abohashem Shady
- Abougabal Mahasen
- Abramson Sandra
- Abrihan Paz
- Acuña Arturo Romero
- Affandi Erwin
- Afzal Muhammad Shehzad
- Agolti Mariela
- Agranovich Svetlana
- Aguadé-Bruix Santiago
- Aguero Roberto Nicolas
- Ahmed Hassan Mohamed Ismail
- Ahmed Taghreed
- Akhter Afroza
- Al Dhuhli Humoud
- Al Kindi Faiza
- Al-Abboud Tarek
- Al-Bulushi Naeema
- Al-Mallah Mouaz
- Alak Maria del Carmen
- Alam Edison
- Alaoui Nadia Ismaili
- Alasnag Mirvat
- Albadr Amjed
- Albalooshi Batool
- Albano Domenico
- Alberguina Lucia Graciela
- Albernaz Siqueira Maria Helena
- Alexanderson-Rosas Erick
- Alfaro Ana
- Ali Mohamed Mandour
- Alkadhi Hatem
- Alkandari Faridah
- Allam Adel
- Allarakha Mohammad Aaftaab
- Almeida Augusto
- Almousalli Omar
- Alongi Pierpaolo
- Alonso Omar
- Alves Togni Paulo Henrique
- Alves Wilson Furlan
- Ananthasubramaniam Karthikeyan
- Anderson Jill
- Andrade Jose Henrique
- Andrade Luciana
- Angelidis George
- Anselmi Carlos
- Ansheles Alexey
- Araújo Roberta
- Archontaki Aikaterini
- Arnone Gaspare
- Arnous Samer
- Arnson Yoav
- Arroñada Guillermo
- Arturo Harold
- Asano Hiroshi
- Ascani Sebastian Perez
- Asfour Ahmed
- Askew Jeffrey
- Assadi Majid
- Astesiano Alfredo
- Astesiano Andrea
- Attanasio Lea
- Atyani Said
- Ayala Sandra
- Ayetey Harold
- Ayodele Tolulope
- Azevedo Guilherme
- Bagatin Elisa
- Bailly Matthieu
- Baldari Sergio
- Balmer-Swain Mallory
- Bang Ji-In
- Banthia Nilesh
- Bar-Shalom Rachel
- Barette Rene
- Baric Ana
- Barneveld Peter
- Barragan Adriana Puente
- Barragan Erika
- Barroso Asela
- Basavaraj Ashok Gangasandra
- Batinic Tonci
- Batista Juan Felipe
- Batyrkhanov Daultai
- Bauckneht Matteo
- Baugh Dainia
- Bayer Richard R.
- Bedi Punit
- Bejai Shereen
- Ben-Rais Nozha
- Benedek Imre
- Benedek Theodora
- Benitez Luis
- Benlabgaa Rabie
- Bennie George
- Benteo Pablo
- Beretta Mario
- Berman Daniel S.
- Bernheim Adam
- Bertelli Paolo
- Bester Ria
- Bettencourt Nuno
- Better Nathan
- Better Nathan
- Beuzeville Scott
- Bezerra Sabbrina
- Bhagat Jinendra Kumar
- Bhargava Rishi
- Bhat Vivek
- Bhatia Mona
- Bhatti Sabha
- Biancardi Rodrigo
- Bianco Francesco
- Bieging Erik
- Biggans Thomas
- Bittencourt Marcio Sommer
- Blanco Isabel
- Blanco Juan
- Blankstein Ron
- Blankstein Ron
- Bloom Stephen
- Blue Sean
- Bluemke David
- Bluemke David A.
- Boktor Raef
- Bom Henry
- Bonelli Juan Manuel
- Bonfiglioli Rachele
- Boni Roberto
- Borges Andressa
- Bouyoucef Salah
- Branch Kelley
- Brandão Simone
- Bravo Paco
- Brothers Jessica
- Bruno Andrea
- Bruno Isabella
- Bråten Anders Tjellaug
- Budoff Matthew
- Buechel Ronny Ralf
- Buga Klara
- Bularga Anda
- Bull Russell
- Bullock-Palmer Renée
- Burandt Angela
- Burg Samuel
- Burger Peter
- Burgul Rajesh
- Burke Floyd W.
- Bush Kelvin
- Busnardo Elena
- Bustos Jose Javier
- Butler Patrick
- Byrne Angela
- Bøttcher Morten
- Cabada Manuel
- Cabeda Estevan Vieira
- Cabrejas Raul
- Cabrera Antonio
- Cachero Jorge
- Cadena Alberto
- Caicedo Carlos
- Calcott Jennifer
- Califaretti Elena
- Camarero Alicia
- Camoni Luca
- Campisi Roxana
- Canal Maria Pedrera
- Candela Candace
- Canderoli Alejandro
- Canessa Jose
- Cantinho Guilhermina
- Cao Dianbo
- Capasso Elizabeth
- Carames Silvia
- Carnevale Aldo
- Carpenter John-Paul
- Carr Loretta
- Carrascosa Patrícia
- Carreira Lara
- Carvajal-Juarez Isabel
- Casoni Roberta
- Castro Bruno
- Castro Gabriel
- Castro Ricardo
- Casáns-Tormo Irene
- Cavalcante Joao
- Cavallo Armando Ugo
- Cavenaghi Giorgio
- Cendoya Oscar
- Cerci Rodrigo
- Cerci Rodrigo J.
- Ceriani Luca
- Chambers Duane
- Chan Virgil
- Chang Donald
- Chang Tien
- Chao Charles
- Chatterjee Saurav
- Chatziioannou Sofia
- Chatzizisis Yiannis
- Cheezum Michael
- Chen Jennifer
- Chen Marcus
- Chen Tiffany
- Cheung Stephen
- Chierichetti Franca
- Chimura Chimura Misato
- Chiocchi Marcello
- Cho Sang-Geon
- Choi Andrew
- Choi Andrew
- Choi Andrew D.
- Chong Woon
- Choudhury Partha
- Chow Benjamin
- Chowdekar Vijay Sai
- Christensen Mette
- Cittanti Corrado
- Clarcq James
- Cognigni Luciano Martin
- Cohen Yosef
- Cohen Yosef A.
- Coie Tchoyoson Lim
- Coles Duncan
- Collaud Carlos
- Collaud Carlos
- Colletta Mauro
- Concha Carmen
- Conti Umberto
- Cordero Ayreen
- Cortes Claudia
- Cortés Filiberto
- Cortés Violeta
- Cossu Alberto
- Courtis Javier
- Cragnolino Daniel
- Crim Matthew
- Cruz Eric
- Cuadra Teresa
- Cuellar-Calabria Hug
- Cunali Fernando
- Cuocolo Alberto
- Cury Roberto
- Cusack David
- Cuzzocrea Marco
- Dabreo Dominique
- Dai Xu
- Daicz Mariana
- Danciu Sorin
- Dantas Roberto
- Dariy Olga
- Datseris Ioannis
- Dautov Tairkhan
- de Amorim Fernandes Fernando
- De Boeck Bart
- De Carvalho Filipe Penna
- De La Peña Erasmo
- De La Vega Alejandro
- De Lorenzo Andrea
- De Macedo Filho Robson
- De Maria Silvia Teresa
- De Rimini Maria Luisa
- De Souza Thiago Ferreira
- De Vincentis Giuseppe
- Decter Bruce
- Del Giudice Eleonora
- Del Riego Horacio
- Del Torto Alberico
- Della Tommasina Veronica
- Deshpande Aparna
- Dettori Fernando
- Deux Jean-François
- Deviggiano Alejandro
- Dhruva Nimish
- Diaz Javier Lopez
- Djuraev Omoa
- Dobson Mark
- Doherty Neil
- Dondi Maurizio
- Dondi Maurizio
- Dorbala Sharmila
- Dorbala Sharmila
- Dougan John
- Doukky Rami
- Downie D'Arne
- Dragonetti Laura
- Drozdova Olga
- Dunbar Anjori
- Durmo Rexhep
- Duvall William
- Dwivedi Girish
- Edmond John
- Edwards Rachael
- Efros-Monsen Elen
- Einstein Andrew J.
- Einstein Andrew J.
- Elison Barry
- Ellis Chris
- Emami Farshad
- Embon Mario
- Engela Jean
- Engelbrecht Gerrit
- Engelmann Vaclav
- Enriquez Ruben Emilio
- Ensinas Jorge
- Erba Paola Anna
- Erthal Fernanda
- Escobar Manuel Valencia
- Escorza Velez Giovanni Alejandro
- Espeche Maria del Huerto Velazquez
- Esquitin Kerry
- Evangelista Laura
- Evbuomwan Osayande
- Faccio Fernando
- Facello Adolfo
- Fairbairn Timothy
- Faletti Riccardo
- Faragasso Evelina
- Faraggi Marc
- Farah Husam
- Farrugia Alexia
- Farsad Mohsen
- Fatima Shazia
- Fentanes Emilio
- Ferencik Maros
- Ferencik Maros
- Fernandes Fabio
- Fernandes Fabio
- Fernandes Juliano
- Ferrando Rodolfo
- Ferreira Antonio
- Ferro Paola
- Feuchtner Gudrun
- Fisher Daniel
- Fitzpatrick Daniel
- Flores Ana Camila
- Florimonte Luigia
- Flotats Albert
- Forsdahl Signe Helene
- Foster Cameron
- Fragkaki Christina
- Franceschi Maja
- Francis Roslyn
- Frantellizzi Viviana
- Frenkel Alex
- Friedrich Matthias
- Fringuelli Fabio Massimo
- Fuentes Cañamero Maria Eugenia
- Fuisz Tony
- Fujimoto Shinichiro
- Fujisue Koichiro
- Fukunaga Tomohisa
- Fukushima Yoshimitsu
- Fukuyama Kae
- Gagarina Nina
- Gaikwad Anand
- Gama-Moreno Manlio
- Gamboa Isabel Berrocal
- Gannon Michael
- Garai Ildiko
- Garashi Masoud
- Garcheva-Tsacheva Marina
- García María Elia
- Garg Ria
- Garofalo Diego
- Gastner Lori
- Gatti Marco
- Gaudiano Angela
- Georgoulias Panagiotis
- Geronazzo Ricardo
- Gerson Myron
- Gheysens Olivier
- Ghimire Ram Kumar
- Ghini Bruno
- Ghoshhajra Brian
- Gimelli Alessia
- Girijanandan Mahapatra Prof Dr
- Giubbini Raffaele
- Giuffrida Francesca
- Glaudemans Andor
- Gleeson Tadhg
- Goda Artan
- Goebel Benjamin
- Goebel Benjamin
- Goldberg Alan
- Goldner Brian
- Gomez Marie Rhiamar
- Gomez Sharon
- Goncalves Luiz
- Gong Lianggeng
- Gongxeka Harlem
- Gonza Natalia
- Gonzalez Carla
- Gonzalez Jorge
- González Luis
- González Ulises
- González-Montecinos Alejandro Becerril
- Goodwin Bruce
- Gopalan Deepa
- Gore Rosco
- Gormsen Lars Christian
- Gottlieb Ilan
- Gracia-López Sandra
- Greenough Robert
- Grossman Gabriel Blacher
- Gräni Christoph
- Gulyaev Vsevolod Milyevich
- Gummow Alistair
- Gunawan Gani
- Gutierrez Villamil Claudia T.
- Gutierrez Goleat
- Gutierrez Lucas
- Gutierrez Yamile Marcos
- Gutierrez Yamile Marcos
- Guzzo Miguel Angel
- Guzzo Miguel Angel
- Gómez Lauchy Juan Manuel
- Habets Jesse
- Habouzit Vincent
- Hadlich Marcelo
- Hafez Mohammed Nassoh
- Hage Fadi
- Haidar Mohamad
- Haider Agha
- Haider Sofia
- Hamilton Mark
- Hamilton-Craig Christian
- Hamirani Yasmin
- Han Dan
- Hapkido Habusari
- Harbinson Mark
- Hartley Thomas
- Hasbak Philip
- Hasbani Victor
- Hashimoto Jun
- Hassan Alia
- Hassan Mona
- Hassen Karen
- Hatfield Mallory
- Hawkins Carolyn
- Hawthorne Katie
- Heath Nicholas
- Hendel Robert
- Hernandez Phillip
- Hernández Gertrudis Sabatel
- Herrera Yariela
- Hess Søren
- Hidalgo Pablo
- Hidayat Basuki
- Hildre Dimmen Jenni-Mari
- Hill Gregory
- Hinterleitner Gerd
- Hirschfeld Cole B.
- Hirschfeld Cole B.
- Holdgaard Paw
- Homans Filip
- Hong Chae Moon
- Horgan Stephen
- Hou Yang
- Houshmand Golnaz
- Hsieh Victar
- Hua Shaw
- Huda Aulia
- Hudson Benjamin
- Huerin Melina
- Huffman Jeff
- Hurwitz Lynne
- Hyafil Fabien
- Ialuna Salvatore
- Ibrahim Ahmed
- Ichikawa Yasutaka
- Iguchi Nobuo
- Iii George Kinzfogl
- Ilic Srdja
- Imai Masamichi
- Inaki Anri
- Irodi Aparna
- Ishimura Hayato
- Iskandrian Ami
- Isobe Satoshi
- Issoufou Djibrillou Moussa
- Itskovich Irina
- Jaimes Claudia
- Jain Shashank
- Janardhanan Rajesh
- Jang Su Jin
- Jason See Jia Hao
- Jawa Zabah
- Jellis Christine
- Jeong Yong Hyu
- Jerome Scott
- Jimenez-Heffernan Amelia
- Jiménez-Santos Moisés
- Johansen Allan
- Johnson Chris
- Johnson Kerryanne
- Joseph Elizabeth
- Joshi Nikhil
- Joshi Subodh
- Juillet de Saint Lager Lucas Alix
- Jukic Mladen
- Junior José Soares
- Jäger Victor
- Jørgensen Arve
- Kadokami Toshiaki
- Kaffas Sameh
- Kalinin Artem
- Kalnina Marika
- Kalra Dinesh
- Kamani Christel H.
- Kameoka Vinícius
- Kaminek Milan
- Kandeel Ahmed
- Kang Won Jun
- Kapitan Miguel
- Kaplan Mitchell
- Karalkin Anatoly
- Karim Noor Khairiah A.
- Kato Takao
- Kaviratne Summanther
- Kawel-Boehm Nadine
- Kay Fernando
- Kay Michael
- Keenan Ross
- Kelion Andrew
- Kelly Faith
- Keng Felix
- Kerins David
- Khalique Omar
- Khiewvan Benjapa
- Khokhar Azhar
- Khushica Purbhoo
- Kiess Marla
- Kim Ji-Young
- Kincl Vladimír
- Kinkhabwala Mona
- Kir Kemal Metin
- Kircher Jacqueline
- Kirkbride Rachael
- Kitt Jamie
- Kmetyuk Yaroslav
- Knafo Galit
- Knuuti Juhani
- Kokkonen Velipekka
- Kokov Alexander
- Komiagiene Renata
- Kontos Michael
- Koopmans Klaas Pieter
- Korol Pavlo
- Kostadinova Irena
- Kostkiewicz Magdalena
- Kottam Anupama
- Koukouraki Sophia
- Koutelou Maria
- Krepp Joseph
- Krohn Isabel
- Kudo Takashi
- Kudo Takashi
- Kumar Mohan Ashok
- Kumar Sukriti
- Kumita Shinichiro
- Kunikowska Jolanta
- Kviecinskiene Giedre
- Kyhl Kasper
- Kyrozi Eleni
- Lahey Ryan
- Lairez Olivier
- Lakhi Hoosen
- Lang Otto
- Larikka Martti
- Laudicella Riccardo
- Layer Jay
- Le Ngoc Ha
- Leccisotti Lucia
- Lederer Karin
- Lee Jaetae
- Lee Joseph
- Lee Ken
- Lee Kenneth
- Lee Steven H.
- Leipsic Jonathon
- Lenturut-Katal Dora
- Leppo Jeffrey
- Lesser John
- Leta Rubén
- Leung Eugene
- Leung Steve
- Leva Lucia
- Lewin Howard
- Lewkowicz Julio Manuel
- Li Caiying
- Li Dong
- Li Sijin
- Li Tao
- Liga Riccardo
- Liguori Carlo
- Lima Adna
- Lima Ronaldo
- Litmanovich Diana
- Liu Hui
- Liu Jinkang
- Liu Yiyan
- Londoño Blair Juan Luis
- Londoño Juan
- Longo Giampiero
- Lopes Rafael Willain
- Lopez-Mattei Juan
- Lopez-Mattei Juan
- Lopez-Mattei Juan
- Lotti Jose Maria
- Louw Lizette
- Lovera Cesar
- Low Chen
- Lu Bin
- Lu Bin
- Lu Yao
- Lugassi Rachel
- Luis Rodrigues Jonathan Carl
- Lumbreras Luis
- Luna Hiram Rivera
- Løvhaugen Pål
- Machado e Silva Ricardo
- Madu Chibuzo
- Madu Ernest
- Maffione Margherita
- Magalhães Tiago
- Magboo Vincent Peter
- Magnussen John
- Magurany Kathleen
- Mai Nghi
- Mai Son Hong
- Majstorov Venjamin
- Mak Sze Mun
- Makhdomi Khalid
- Malan Nico
- Maldonado Alejandro
- Maleki Majid
- Malkovskiy Eli
- Malkovskiy Eli
- Mancini Maria Elisabetta
- Mander Gordon
- Manders Jeroen
- Manka Robert
- Mansy Ahmad
- Maor Moalem Israel Shlomo
- Marcassa Claudio
- Markowitz Jeremy
- Marn Amanda
- Marousa Ntouskou
- Maroz-Vadalazhskaya Natallia
- Marquez Alejandra
- Marquez-Cabeza Juan Javier
- Martin Francisco
- Martin Jon
- Martinez de Alegria Anxo
- Maruno Hirotaka
- Masoli Osvaldo
- Masoli Osvaldo Horacio
- Massardo Teresa
- Mastrocola Luiz Eduardo
- Mastrovito Edgardo
- Mataciunas Mindaugas
- Mataki Hiroyuki
- Matis Stephen E.
- Matos Luis
- Matushita Cristina Sebastião
- Maurice Hany
- Maurovich-Horvat Pál
- Maurovich-Horvat Pál
- Mayoraz Matias
- Mcalindon Elisa
- Mckenna Michael
- Mcrae Tony
- Medakovic Petar
- Medeiros Fábio
- Medina Francisco
- Medina John Michael
- Medjahedi Abdelkader
- Meehan Conor
- Melado Graciela Eva
- Mele Anibal
- Mendoza Fernando
- Meneghetti José Claudio
- Menezes de Siqueira Maria Eduarda
- Menezes Leon
- Menéndez Rayner
- Merani Maria Fernanda
- Meretta Alejandro Horacio
- Merhige Michael
- Mesquita Cláudio Tinoco
- Migunova Ekaterina
- Milan Elisa
- Miller Robert
- Milos Katarina
- Min David
- Mirzaei Siroos
- Mititelu Raluca
- Mitra Deepanjan
- Mittal Bhagwant Rai
- Miyagawa Masao
- Modiselle Moshe
- Moffitt Chanan
- Molteni Susana
- Moncayo Antonio Calderón
- Moncayo Antonio Calderón
- Moncher Karen
- Monroy Edgar
- Monte Guilherme Urpia
- Montecinos Marcos
- Moore Warren
- Mor Maya
- Morayati Shamil
- More Stuart
- Morelos Martha
- Moreno-Reyes Rodrigo
- Morgan-Hughes Gareth
- Morimoto Ryota
- Moroi Masao
- Morozova Olga
- Morris Michael
- Moss Alastair
- Mossa-Basha Mahmud
- Mrsic Zorana
- Mukti Anggoro Praja
- Murphy David
- Murphy Mark
- Murray Anthony
- Murray John
- Murthy Venkatesh
- Murton Fiona
- Muskal Noam
- Mut Fernando
- Muyinda Zerida
- Muñoz Gabriel Castro
- Mykhalchenko Olena
- Myo Khin Pa
- Nabil Sherif
- Nagamachi Shigeki
- Nagpal Prashant
- Naidoo Mathava
- Nailli Qais
- Nakajima Kenichi
- Nakata Tomoaki
- Nakazato Ryo
- Namgung Chang Kyeong
- Nanasato Mamoru
- Nanayakkara Damayanthi
- Nandurkar Dee
- Naojee Ambedhkar Shantaram
- Napier Kyle
- Nardi Barbara
- Narula Jagat
- Narula Jagat
- Naseer Hamid
- Nasery Mohammad Nawaz
- Naue Vania
- Naves Danilo
- Naya Masanao
- Neill Johanne
- Nelson Katarina
- Ng Ming Yen
- Nguyen Xuan Canh
- Nicol Edward
- Nieves A López De Munaín Maria
- Nijjar Prabhjot
- Nogueira Ramos Rodrigo Rizzo
- Noguera Eduardo
- Nolasco Roberto
- Nomura Cesar
- Norgaard Bjarne Linde
- Norikane Takashi
- Norton Carolina Bas
- Novoa Carlos
- Nunura Felix
- Nørgaard Bjarne Linde
- O'Brien Julie
- O'Rourke Edward
- O'Sullivan Patricia
- Obaldo Jerry
- Occleshaw Christopher
- Ohta Yasutoshi
- Oikonomou Anastasia
- Okarvi Subhani
- Okayama Satoshi
- Okizaki Atsutaka
- Oliveira Joao Bruno
- Ombati Kevin
- Onimode Yetunde
- Ornelas Mario
- Ortellado José
- Ortga Ramirez Jose Alberto
- Osman Medhat
- Otomi Yoichi
- Otsuka Hideki
- Ozair Ahmad
- Paar Maja Hrabak
- Pabon Luz
- Pacella Sara
- Padma Savenadia
- Paez Diana
- Paez Diana
- Paixao Eduardo
- Panagidis Christoforos
- Pandos George
- Parwani Purvi
- Parwani Purvi
- Parwani Purvi
- Pascual Thomas N. B.
- Pascual Thomas N. B.
- Pasquet Agnès
- Passen Edward
- Pastrana Davidson
- Patel Amit
- Patel Chetan
- Patel Dilip
- Patel Ravi
- Patel Shivani
- Patel Tapan
- Pathmaraj Kunthi
- Patil Pravin
- Paul Ryan
- Pawhay Christian Michael
- Pedras Felipe Villela
- Peebles Charles
- Peiro Virginia
- Peix Amalia
- Pepe Giovanna
- Perez Alfredo
- Perez Ricardo Ruano
- Persic Viktor
- Petrou Ioannis
- Phillips Lawrence
- Pianta Diego Bromfman
- Picard Christian
- Pineda Mauricio
- Pinto Ibraim
- Pitman Alexander
- Pliatsek Volodymyr
- Poksi Anne
- Pollono Pablo
- Polsani Venkateshwar
- Poludasu Rajaram
- Pomerantz Brian
- Pontone Gianluca
- Pool Stefan
- Porter Thomas
- Pospelov Viktor
- Possetti Priscila
- Poulter Rohan
- Prawiro Djoko
- Preciado-Anaya Andrés
- Preciado-Gutiérrez Óscar Ulises
- Premaratne Manuja
- Premprabha Teerapon
- Prentice Ryan
- Prior David
- Prior John O.
- Probst Stephan
- Proffit Franck
- Prpic Marina
- Pubul-Nuñez Virginia
- Pugliese Francesca
- Pujol Maria Paula
- Pulizzi Sabina
- Punda Ante
- Pursnani Amit
- Pynda Yaroslav
- Pynda Yaroslav
- Quartuccio Natale
- Quinon Alvin
- Quinta Mayra
- Rabbat Mark
- Radzinschi Alejandro
- Raggi Paolo
- Raggi Paolo
- Raimondi Gustavo
- Rajbanshi Bijoy
- Rajvong Sonexay
- Ramamurti Suresh
- Ramkumar Prasad Guntur
- Rampin Lucia
- Ramírez Nelsy Gonzalez
- Randazzo Michael
- Randazzo Michael J.
- Ranser Sara
- Rawashdeh Mohammad
- Rayo Madrid Juan Ignacio
- Redruello Marcela
- Regaieg Hamza
- Reichmuth Luise
- Repasos Evangelos
- Rey Cristina Rodríguez
- Riaz Musab
- Ricci Fabrizio
- Rich Florence
- Ridley Lloyd
- Robinson Austin
- Robles Kim
- Rocha Ricardo
- Rochela Luis
- Rodrigues Alfredo
- Rodrigues Carlos
- Rodriguez Daniel Calderon
- Rodríguez Cesar
- Rodríguez Marina
- Rodríguez Matías
- Roelants Veronique
- Rofe Christopher
- Roifman Idan
- Rojas Juan Carlos
- Romantini Leila
- Romero Romina Lorena
- Rominger Axel
- Roque Vanegas Hector Bladimir
- Rorie Mark
- Rosales Uvera Sandra Graciela
- Rossini Pierluigi
- Rostami Maryam Tajik
- Rovaletti Federico
- Rozikhodjaeva Gulnora
- Rubini Giuseppe
- Ruiz Diego
- Ruiz Joaquín
- Rumberger John
- Russell Raymond
- Russo Vincenzo
- Rutherford Natalie
- Ryzhkova Daria
- Ríos Raúl Araujo
- Rønnow Sand Niels Peter
- Saadullah Mohammad
- Sabharwal Nikant
- Sabra Philip
- Sacchetti Gian Mauro
- Sadler Diego
- Saifullina Guzaliya
- Saito Masaki
- Sakanyan Mari
- Sakata Sakata Yasushi
- Salehi Hamid
- Salobir Barbara Gužic
- Sambuceti Gianmario
- Samuel Anthony
- San Miguel Lucas
- Sanches Adelina
- Sandoval Sigelinda
- Santana Sara
- Sara da Silva Leonardo
- Sarai Masayoshi
- Saranovic Dragana Sobic
- Sarda-Mantel Laure
- Sasse Alexander
- Sato Daisuke
- Satyr Maryna
- Saunders Connor
- Saxena Sudhir
- Sayman Haluk
- Sazonova Svetlana
- Scarano Massimo
- Scarlett Luke
- Schemmer Mary
- Schmidt Erzsébet
- Schneider Roman P.
- Schoepf U. Joseph
- Schofield Rebecca
- Scholte Arthur
- Scholtens Asbjørn
- Scholtz Leonie
- Schvartzman Paulo
- Sciagrà Roberto
- Sebikali Mugisha Julius
- Sekar Ramkumar
- Sellem Ali
- Semple Thomas
- Seneviratne Sujith
- Sengupta Shantanu
- Senra Tiago
- Sereegotov Erdenechimeg
- Sergienko Vladimir
- Sergienko Vladimir
- Sevilla Ana
- Shaaban Mahmoud
- Shah Nishant
- Shah Nishant R.
- Shah Samir
- Shalev Aryeh
- Shanbhag Sujata
- Sharma Gaurav
- Sharma Naveen
- Shaw Leslee J.
- Shaw Leslee J.
- Shayani Steven
- Shetty Deepa
- Shiozaki Afonso
- Shiraishi Shinya
- Shirani Jamshid
- Shirka Ervina
- Shivaram Pushpa
- Shrestha Ganesh
- Shulman Jonathan
- Shurupova Irina
- Sierra-Galan Lilia M.
- Sierra-Galan Lilia M.
- Sigman Steven
- Silva Fábio Martins
- Simanek Milan
- Simon Mitch
- Simonsson Magnus
- Singh Bhanupriya
- Singh Santosh
- Sinitsyn Valentin
- Siqueira Cristiano
- Siu Silvia
- Slart Riemer
- Slim Ahmad
- Small Gary
- Smanio Paola
- Smith Alexandra
- Smith David
- So Young
- Soares Carlos Eduardo
- Soeriadi Erwin Affandi
- Solanki Vijay
- Solari Lucrecia
- Soldat-Stankovic Valentina
- Soli Idrissa Adamou
- Soman Prem
- Sood Aditya
- Sood Ashwani
- Sperandio Massimiliano
- Spiro Bernardo
- Srichai-Parsia Monvadi Barbara
- Stan Claudiu Adrian
- Stankovic Sinisa
- Stanton Tony
- Stavrou Petros
- Stefanelli Antonella
- Steffensen Rolf
- Strada Bruno
- Streeter James
- Strouhal Peter
- Stuart Murch
- Stubbs Michael
- Subedi Deepak
- Sueldo Claudio Pereyra
- Sun Kai
- Suwa Yoshinobu
- Swainson Ian
- Syawaluddin Hilman
- Syed Ghulam
- Szilveszter Balint
- T Albert
- Tacher Vania
- Tag Naima
- Takanami Kentaro
- Takehana Kazuya
- Taki Junichi
- Taleb Sara
- Tamaki Nagara
- Tandon Vikas
- Tang Gongshun
- Tang Jeanelle Margareth
- Taniguchi Yasuyo
- Taubman Kim
- Tawakol Ahmed
- Taylor Andrew
- Tecson Bettina
- Teragawa Hiroki
- Theng Youdaline
- Thientunyakit Tanyaluck
- Thimister Paul
- Thomas Dustin
- Thomas Paul
- Thomassen Anders
- Thompson Randall
- Thu Phyo Si
- To Andrew
- Tomas Miguel Santaularia
- Tomizawa Nobuo
- Topping William
- Torbet Tara
- Torreao Jorge
- Torres Rafael
- Traverso Sonia
- Traverzo Sonia Simona
- Trifonova Tatjana
- Trinidad Desiree
- Trivedi Adwait
- Tsujita Kenichi
- Tweed Katharine
- Udugama Chandraguptha
- Uellendahl Marly
- Ullery Shawn
- Umeji Kyoko
- Unger Steven
- Unzek Samuel
- Upton Anthony
- Uretsky Seth
- Uson Kristine Joy
- Ussov Wladimir Yurievich
- Uusitalo Valtteri
- Uy Mila
- Vajauskas Donatas
- Vakhromeeva Margarita
- Valiullina Nailya
- Vallejo Enrique
- Valles Mario
- Vallurupalli Srikanth
- Vallée Jean-Paul
- Valsamaki Pipitsa
- Vamadevan Shankar
- Van Asperen Erik-Jan
- Van De Heyning Caroline M.
- Van Gaal William
- Van Pelt Niels
- Vangu Mboyo
- Vargas Luis Salazar
- Vasquez Andres
- Vavlukis Marija
- Velez Mayra Sanchez
- Veltman Niels
- Ventroni Guido
- Vergel Damiana
- Verjans Johan
- Verma Atul
- Verma Vikas
- Verschure Derk
- Veríssimo Otávia
- Villines Todd C.
- Villines Todd C.
- Vitola Joao V.
- Vitola Joao V.
- Vondrak Andrej
- Voutnis Demetrius
- Vuuren Magritha Jv
- Várady Edit
- Vázquez Manuel Castillo
- Wagenaar Nils
- Wakabayashi Yasushi
- Waller Alfonso
- Waltrick Roberto
- Wang Ellen
- Wang Jian
- Wang Ximing
- Wang Yifan
- Wang Yining
- Wang Zhao-Qian
- Ward Parker
- Wayne Victor
- Weihmuller Juan Sebastian
- Weir-Mccall Jonathan
- Weiss Konrad
- Weissman Gaby
- Wesbey George
- White James
- White Kelly
- Williams Michelle C.
- Williams Michelle C.
- Wilson Peter
- Winchester David
- Winchester David
- Wolcan Juan
- Wolinsky David
- Won Kyoung Sook
- Wong David
- Wong Kirby
- Wu Jiang
- Wu Zhifang
- Xia Liming
- Xiao Jiangxi
- Xu Lei
- Xu Zhuoran
- Yamada Shinichiro
- Yamazaki Shinya
- Yang Youyou
- Yew Min Sen
- Yin Wu
- Yoneyama Tatsuya
- Yost Sandra
- Young Calum
- Younger John
- Younis Muhammad Numair
- Yu Jianqun
- Yuan Li
- Zaid Eed Abu
- Zakavi Seyed Rasoul
- Zapparoli Marcello
- Zavadovsky Konstantin
- Zeffiro Susana
- Zeidán Nahla
- Zerahn Bo
- Zgaljardic Michael
- Zhang Longjiang
- Zhang Tong
- Zhang Xiaoli
- Zhang Yong-Gao
- Zhu Li
- Zhuravlev Kirill
- Zoboli Stefania
- Zukotynski Katherine
- Zuluaga Alejandro
- Øvrehus Kristian Altern
- Štalc Monika
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2021
- Field of study
Objectives: This study sought to quantify and compare the decline in volumes of cardiovascular procedures between the United States and non-US institutions during the early phase of the coronavirus disease-2019 (COVID-19) pandemic.
Background: The COVID-19 pandemic has disrupted the care of many non-COVID-19 illnesses. Reductions in diagnostic cardiovascular testing around the world have led to concerns over the implications of reduced testing for cardiovascular disease (CVD) morbidity and mortality.
Methods: Data were submitted to the INCAPS-COVID (International Atomic Energy Agency Non-Invasive Cardiology Protocols Study of COVID-19), a multinational registry comprising 909 institutions in 108 countries (including 155 facilities in 40 U.S. states), assessing the impact of the COVID-19 pandemic on volumes of diagnostic cardiovascular procedures. Data were obtained for April 2020 and compared with volumes of baseline procedures from March 2019. We compared laboratory characteristics, practices, and procedure volumes between U.S. and non-U.S. facilities and between U.S. geographic regions and identified factors associated with volume reduction in the United States.
Results: Reductions in the volumes of procedures in the United States were similar to those in non-U.S. facilities (68% vs. 63%, respectively; p = 0.237), although U.S. facilities reported greater reductions in invasive coronary angiography (69% vs. 53%, respectively; p < 0.001). Significantly more U.S. facilities reported increased use of telehealth and patient screening measures than non-U.S. facilities, such as temperature checks, symptom screenings, and COVID-19 testing. Reductions in volumes of procedures differed between U.S. regions, with larger declines observed in the Northeast (76%) and Midwest (74%) than in the South (62%) and West (44%). Prevalence of COVID-19, staff redeployments, outpatient centers, and urban centers were associated with greater reductions in volume in U.S. facilities in a multivariable analysis.
Conclusions: We observed marked reductions in U.S. cardiovascular testing in the early phase of the pandemic and significant variability between U.S. regions. The association between reductions of volumes and COVID-19 prevalence in the United States highlighted the need for proactive efforts to maintain access to cardiovascular testing in areas most affected by outbreaks of COVID-19 infection
Possible interpretations of the joint observations of UHECR arrival directions using data recorded at the Telescope Array and the Pierre Auger Observatory
- Author
- Abbasi Rasha
- Abdul Halim Adila
- Abreu Pedro
- Abu-Zayyad Tareq
- Aglietta Marco
- Allekotte Ingomar
- Allen Monica
- Almeida Cheminant Kévin
- Almeida Rogerio M. De
- Almela Alejandro
- Aloisio Roberto
- Alvarez-Muniz Jaime
- Ammerman Yebra Juan
- Anastasi Gioacchino Alex
- Anchordoqui Luis A.
- Andrada Belén
- Andringa Sofia
- Anjos Joao Dos
- Anjos Rita Cassia Dos
- Arai Yuto
- Aramo Carla
- Araújo Ferreira Paulo Ricardo
- Arimura Ryuhei
- Arnone Enrico
- Arteaga Velazquez Juan Carlos
- Asorey Hernán Gonzalo
- Assis Pedro
- Avila Gualberto
- Avocone Emanuele
- Badescu Alina Mihaela
- Bakalova Alena
- Balaceanu Alexandru
- Barbato Felicia
- Barcikowski Elliott
- Bartz Mocellin Adriel
- Bellido Jose A.
- Belz John
- Berat Corinne
- Bergman Douglas
- Bertaina Mario Edoardo
- Bhatta Gopal
- Bianciotto Marta
- Biermann Peter L.
- Binet Virginia
- Bismark Kathrin
- Bister Teresa
- Biteau Jonathan
- Blake Samuel
- Blazek Jiri
- Bleve Carla
- Blümer Johannes
- Bohacova Martina
- Boncioli Denise
- Bonifazi Carla
- Bonneau Arbeletche Luan
- Borodai Nataliia
- Brack Jeffrey
- Brichetto Orchera P. Gabriel
- Briechle Florian Lukas
- Bueno Antonio
- Buitink Stijn
- Buscemi Mario
- Bwembya Anthony
- Büsken Max
- Caballero-Mora Karen S.
- Cabana-Freire Sergio
- Caccianiga Lorenzo
- Cady Robert
- Caracas Ioana
- Caruso Rossella
- Castellina Antonella
- Catalani Fernando
- Cataldi Gabriella
- Cazon Lorenzo
- Cerda Marcos
- Cermenati Alessandro
- Cheon ByongGu
- Chiba Jyunsei
- Chikawa Michiyuki
- Chinellato Jose Augusto
- Chudoba Jiří
- Chytka Ladislav
- Clay Roger W.
- Cobos Cerutti Agustín
- Colalillo Roberta
- Coleman Alan
- Coluccia Maria Rita
- Conceição Rúben
- Condorelli Antonio
- Consolati Giovanni
- Conte Matteo
- Convenga Fabio
- Correia dos Santos Diego
- Costa Pedro J.
- Covault Corbin
- Cristinziani Markus
- Cruz Sanchez Carlo Salvattore
- D\u27Olivo Juan Carlos
- Dasso Sergio
- Daumiller Kai
- Dawson Bruce R.
- Deligny Olivier
- Denner Nikolas
- Deval Luca
- Dobre Madalina
- Dobrigkeit Carola
- Domingues Mendes Luis Miguel
- Ebr Jan
- Ellwanger Fiona H.
- Emam Mohamed
- Engel Ralph
- Epicoco Italo
- Erdmann Martin
- Etchegoyen Alberto
- Evoli Carmelo
- Falcke Heino
- Farmer John
- Farrar Glennys R.
- Fauth Anderson
- Fazzini Norberto
- Feldbusch Fridtjof
- Fenu Francesco
- Fernandes Alexandra
- Fick Brian
- Figueira Juan Manuel
- Filipcic Andrej
- Fitoussi Thomas
- Flaggs Benjamin
- Fodran Tomáš
- Fujii Toshihiro
- Fujisue Kozo
- Fujita Keitaro
- Fujiwara Ryota
- Fukushima Masaki
- Fukushima Ryota
- Furlich Greg
- Fuster Alan
- Galea Cristina
- Galelli Claudio
- García Beatriz
- Gaudu Chloé
- Gemmeke Hartmut
- Gesualdi Flavia
- Gherghel-Lascu Alexandru
- Ghia Piera Luisa
- Giaccari Ugo
- Giammarchi Marco
- Glombitza Jonas
- Gobbi Fabian
- Gollan Fernando
- Golup Geraldina
- Gongora Juan Pablo
- Gonzalez Nicolas Martin
- Gonzalez Ricardo
- González Juan Manuel
- Goos Isabel
- Gora Dariusz
- Gorgi Alessio
- Gottowik Marvin
- Grubb Trent D.
- Guarino Fausto
- Guedes Germano
- Guido Eleonora
- Gómez Berisso Mariano
- Gómez Vitale Primo F.
- Hahn Steffen Traugott
- Hamal Petr
- Hampel Matías Rolf
- Hanlon William
- Hansen Patricia María
- Harari Diego
- Harvey Violet M.
- Haungs Andreas
- Hayashi Motoki
- Hayashida Naoaki
- Hebbeker Thomas
- Hibino Kinya
- Higuchi Ryo
- Hojvat Carlos
- Honda Ken
- Horvath Pavel
- Hrabovsky Miroslav
- Huege Tim
- Hörandel Jörg R.
- Ikeda Daisuke
- Inadomi Taichi
- Inoue Naoya
- Insolia Antonio
- Isar Paula Gina
- Ishii Takaaki
- Ito Hirotaka
- Ivanov Dmitri
- Iwakura Hirokazu
- Iwasaki Aoi
- Janecek Petr
- Jeong Hyoming
- Jeong Soomin
- Jesus Joaquin De
- Johnsen Jeffrey A.
- Jong Sijbrand J. De
- Jui Charlie
- Jurysek Jakub
- Kadota Kenichi
- Kakimoto Fumio
- Kalashev Oleg
- Kampert Karl-Heinz
- Kasahara Katsuaki
- Kasami Saori
- Kawai Hideyuki
- Kawakami Saburo
- Kawana Shingo
- Kawata Katsumasa
- Keilhauer Bianca
- Khakurdikar Abha
- Kharuk Ivan
- Kido Eiji
- Kim HangBae
- Kim Jihee
- Kim Jihyun
- Kim Min Hyo
- Kim Sang Woo
- Kimura Yusuke
- Kishigami Shoichi
- Kizakke Covilakam Varada Varma
- Klages Hans
- Kleifges Matthias
- Knapp Felix
- Kubota Yuto
- Kunka Norbert
- Kurisu Shinnosuke
- Kuzmin Vladim
- Kuznetsov Mikhail
- Kwon Youngjoon
- Kääpä Alex
- Lago Bruno L.
- Langner Niklas
- Lee Kwangho
- Leigui de Oliveira Marcelo Augusto
- Lema-Capeans Yago
- Lenok Vladimir
- Letessier-Selvon Antoine
- Lhenry-Yvon Isabelle
- Lo Presti Domenico
- Lopes Luis
- Lu Lu
- Lubsandorzhiev BayarJon Paul
- Luce Quentin
- Lundquist Jon Paul
- Machado Payeras Allan
- Machida Kazuhiro
- Majercakova Margita
- Mandat Dusan
- Manning Bradley C.
- Mantsch Paul
- Marafico Sullivan
- Mariani Federico Maria
- Mariazzi Analisa
- Maris Ioana Codrina
- Marsella Giovanni
- Martello Daniele
- Martinelli Sara
- Martins Miguel A.
- Martínez Bravo Oscar
- Mastrodicasa Massimo
- Mathes Hermann-Josef
- Matsumiya Hiroyuki
- Matsuyama Toshio
- Matteo Armando Di
- Matthews James
- Matthews John
- Matthiae Giorgio
- Mayotte Eric William
- Mayotte Sonja
- Mayta Rosa
- Mazur Peter
- Medina-Tanco Gustavo
- Meinert Janning
- Mello Neto João De
- Melo Diego
- Menshikov Alexander
- Merx Carmen
- Michal Stanislav
- Micheletti Maria Isabel
- Minamino Mayuko
- Miramonti Lino
- Mitri Ivan De
- Mollerach Silvia
- Montanet François
- Morejon Leonel
- Morello Carlo
- Mukai Keijiro
- Mulrey Katharine
- Mussa Roberto
- Muzio Marco Stein
- Myers Isaac
- Müller Ana L.
- Nagataki Shigehiro
- Nakai Kei
- Nakamura Ryo
- Nakamura Tomoyuki
- Nakamura Toru
- Nakamura Yuya
- Nakazawa Arata
- Namasaka Wilson M.
- Negi Shefali
- Nellen Lukas
- Nguyen Khoa
- Nicora Gabriela
- Niculescu-Oglinzanu Mihai
- Niechciol Marcus
- Nishio Eiji
- Nitz Dave
- Nonaka Toshiyuki
- Nosek Dalibor
- Novotný Vladimír
- Nozka Libor
- Nucita Achille
- Nunez Luis A.
- Oda Hiroyuki
- Ogio Shoichi
- Ohnishi Munehiro
- Ohoka Hideyuki
- Oku Yuya
- Okuda Takeshi
- Oliveira Franco Danelise De
- Oliveira Cainã
- Oliveira Jaime De
- Omura Yugo
- Ono Masaomi
- Onogi Ryota
- Oshima Akitoshi
- OZAWA Shunsuke
- Palatka Miroslav
- Pallotta Juan
- Palma Francesco De
- Panja Shayoni
- Parente Gonzalo
- Park Il Hung
- Paulsen Therese
- Pawlowsky Jannis
- Pech Miroslav
- Pelayo Rodrigo
- Pereira Martins Edyvania Emily
- Pereira Luiz Augusto
- Perez Armand Johnnier
- Perrone Lorenzo
- Petrera Sergio
- Petrucci Camilla
- Pierog Tanguy
- Pierre Auger Collaboration
- Pimenta Mário
- Platino Manuel
- Pont Bjarni
- Popolo Antonino Del
- Pothast Mart
- Potts Matt
- Pourmohammad Shahvar Mohsen
- Privitera Paolo
- Prouza Michael
- Pshirkov Maxim
- Puyleart Andrew
- Pérez Bertolli Carmina
- Pękala Jan
- Querchfeld Sven
- Rautenberg Julian
- Ravignani Diego
- Reininghaus Maximilian
- Remington Jackson
- Ridky Jan
- Riehn Felix
- Risse Markus
- Rizi Vincenzo
- Rodrigues Carvalho Washington De
- Rodriguez Rojo Jorge Rubén
- Rodriguez Doug
- Rodriguez Ezequiel
- Roncoroni Matías J.
- Rossoni Simone
- Roth Markus
- Roulet Esteban
- Rovero Adrian
- Rubtsov Grigory
- Ruehl Philip
- Ryu Dongsu
- Saftoiu Alexandra
- Sagawa Hiroyuki
- Sahara Ryosuke
- Saharan Mohit
- Saito Yasunori
- Sakaki Naoto
- Sako Takashi
- Sakurai Nobuyuki
- Salamida Francesco
- Salazar Humberto Ibarguen
- Salina Gaetano
- Sanabria Gomez Jose
- Sano Kengo
- Santos Edivaldo Moura
- Santos Eva
- Sarazin Fred
- Sarmento Raul
- Sato Koki
- Sato Ricardo
- Savina Pierpaolo
- Scherini Viviana
- Schieler Harald
- Schimassek Martin
- Schimp Michael
- Schlüter Felix
- Schmidt David
- Scholten Olaf
- Schoorlemmer Harm
- Schovanek Petr
- Schröder Frank G.
- Schulte Josina
- Schulz Tobias
- Schäfer Christoph M.
- Sciutto Sergio J.
- Scornavacche Marina
- Segreto Alberto
- Sehgal Srijan
- Seki Terutsugu
- Sekino Koichi
- Shah Priti
- Shibasaki Yuma
- Shibata Fumiya
- Shibata Norimichi
- Shibata Tatsunobu
- Shimodaira Hideaki
- Shin Bokkyun
- Shin Heungsu
- Shinto Daiki
- Shivashankara Shima Ujjani
- Sigl Guenter
- Silli Gaia
- Sima Octavian
- Simon Frank
- Smau Raluca
- Smida Radomir
- Smith Jeremy
- Sokolsky Pierre
- Sommers Paul
- Sone Naohiro
- Soriano Jorge F.
- Souza Vitor De
- Squartini Ruben
- Stadelmaier Maximilian
- Stanca Denis
- Stanič Samo
- Stasielak Jaroslaw
- Stassi Patrick
- Stokes Ben
- Straub Maximilian
- Stroman Tom
- Strähnz Simon
- Suomijarvi Tiina
- Supanitsky A. Daniel
- Suárez-Durán Mauricio
- Svozilikova Zuzana
- Szadkowski Zbigniew
- Sánchez Federico Andrés
- Takagi Yoshinori
- Takahashi Yuichi
- Takamura Mai
- Takeda Masahiro
- Takeishi Ryuji
- Taketa Akimichi
- Takita Masato
- Tameda Yuichiro
- Tanaka Hideki
- Tanaka Koichi
- Tanaka Manobu
- Tanoue Yuta
- Tapia Alex
- Taricco Carla
- Telescope Array
- Thomas Stanton
- Thomson Gordon
- Timmermans Charles
- Tinyakov Petr
- Tkachenko Olena
- Tkachev Igor
- Tobiska Petr
- Todero Peixoto Carlos J.
- Tokuno Hisono
- Tomida Taka
- Tomé Bernardo
- Torrès Zoé
- Travaini Andres
- Travnicek Petr
- Trimarelli Caterina
- Troitsky Sergey
- Tsuda Ryosuke
- Tsunesada Yoshiki
- Tueros Matias Jorge
- Uchihori Yukio
- Udo Shigeharu
- Uehama Takafumi
- Unger Michael
- Urban Federico
- Vaclavek Lukáš
- Vacula Martin
- Valdés Galicia Jose F.
- Valore Laura
- Varela Enrique
- Veberic Darko
- Ventura Cynthia
- Vergara Quispe Indira D.
- Verzi Valerio
- Vicha Jakub
- Vink Jacco
- Vito Emanuele De
- Vlastimil Jilek
- Vorobiov Serguei
- Vásquez-Ramírez Adriana
- Watanabe Clara Keiko Oliveira
- Watson Alan
- Weindl Andreas
- Wiencke Lawrence
- Wilczyński Henryk
- Wittkowski David
- Wong Tiffany
- Wundheiler Brian
- Yada Kohei
- Yamamoto Mashu
- Yamazaki Katsuya
- Yang Jongmann
- Yashiro Kenta
- Yoshida Fugo
- Yoshioka Tsubasa
- Yue Babobiao
- Yushkov Alexey
- Zapparrata Orazio
- Zas Enrique
- Zavrtanik Danilo
- Zavrtanik Marko
- Zhezher Yana
- Zundel Zach
- Publication venue
- Scuola Internazionale Superiore di Studi Avanzati
- Publication date
- 24/10/2023
- Field of study
Search for dark matter produced in association with bottom or top quarks in √s = 13 TeV pp collisions with the ATLAS detector
- Author
- Aaboud Morad
- Aad Georges
- Abbott Brad
- Abdinov Ovsat
- Abeloos Baptiste
- Abidi Syed
- AbouZeid Ossama
- Abraham Nicola
- Abramowicz Halina
- Abreu Henso
- Abreu Ricardo
- Abulaiti Yiming
- Acharya Bobby
- Adachi Shunsuke
- Adamczyk Leszek
- Adelman Jahred
- Adersberger Michael
- Adye Tim
- Affolder Tony
- Afik Yoav
- Agatonovic-Jovin Tatjana
- Agheorghiesei Catalin
- Aguilar-Saavedra Juan
- Ahlen Steven
- Ahmadov Faig
- Aielli Giulio
- Akatsuka Shunichi
- Akerstedt Henrik
- Akilli Ece
- Akimov Andrei
- Alberghi Gian
- Albert Justin
- Albicocco Pietro
- Alconada Verzini Maria
- Alderweireldt Sara
- Aleksa Martin
- Aleksandrov Igor
- Alexa Calin
- Alexander Gideon
- Alexopoulos Theodoros
- Alhroob Muhammad
- Ali Babar
- Aliev Malik
- Alimonti Gianluca
- Alison John
- Alkire Steven
- Allbrooke Benedict
- Allen Benjamin
- Allport Phillip
- Aloisio Alberto
- Alonso Alejandro
- Alonso Francisco
- Alpigiani Cristiano
- Alshehri Azzah
- Alstaty Mahmoud
- Alvarez Gonzalez Barbara
- Alviggi Mariagrazia
- Amadio Brian
- Amaral Coutinho Yara
- Amelung Christoph
- Amidei Dante
- Amor Dos Santos Susana
- Amoroso Simone
- Anastopoulos Christos
- Ancu Lucian
- Andari Nansi
- Andeen Timothy
- Anders Christoph
- Anders John
- Anderson Kelby
- Andreazza Attilio
- Andrei George
- Angelidakis Stylianos
- Angelozzi Ivan
- Angerami Aaron
- Anisenkov Alexey
- Anjos Nuno
- Annovi Alberto
- Antel Claire
- Antonelli Mario
- Antonov Alexey
- Antrim Daniel
- Anulli Fabio
- Aoki Masato
- Aperio Bella Ludovica
- Arabidze Giorgi
- Arai Yasuo
- Araque Juan
- Araujo Ferraz Victor
- Arce Ayana
- Ardell Rose
- Arduh Francisco
- Arguin Jean-Francois
- Argyropoulos Spyridon
- Arik Metin
- Armbruster Aaron
- Armitage Lewis
- Arnaez Olivier
- Arnold Hannah
- Arratia Miguel
- Arslan Ozan
- Artamonov Andrei
- Artoni Giacomo
- Artz Sebastian
- Asai Shoji
- Asbah Nedaa
- Ashkenazi Adi
- Asquith Lily
- Assamagan Ketevi
- Astalos Robert
- Atkinson Markus
- Atlay Naim
- Augsten Kamil
- Avolio Giuseppe
- Axen Bradley
- Ayoub Mohamad
- Azuelos Georges
- Baas Alessandra
- Baca Matthew
- Bachacou Henri
- Bachas Konstantinos
- Backes Moritz
- Bagnaia Paolo
- Bahmani Marzieh
- Bahrasemani Sina
- Baines John
- Bajic Milena
- Baker Oliver
- Bakker Pepijn
- Baldin Evgenii
- Balek Petr
- Balli Fabrice
- Balunas William
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- Bandyopadhyay Anjishnu
- Banerjee Swagato
- Bannoura Arwa
- Barak Liron
- Barberio Elisabetta
- Barberis Dario
- Barbero Marlon
- Barillari Teresa
- Barisits Martin-Stefan
- Barkeloo Jason
- Barklow Timothy
- Barlow Nick
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- Barnett Michael
- Barnovska-Blenessy Zuzana
- Baroncelli Antonio
- Barone Gaetano
- Barr Alan
- Barranco Navarro Laura
- Barreiro Guimarães da Costa João
- Barreiro Fernando
- Barros Vale Maria
- Bartoldus Rainer
- Barton Adam
- Bartos Pavol
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- Beacham James
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- Beck Helge
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- Becker Maurice
- Becot Cyril
- Beddall Andrew
- Beddall Ayda
- Bednyakov Vadim
- Bedognetti Matteo
- Bee Christopher
- Beermann Thomas
- Begalli Marcia
- Begel Michael
- Behr Janna
- Bell Andrew
- Bella Gideon
- Bellagamba Lorenzo
- Bellerive Alain
- Bellomo Massimiliano
- Belotskiy Konstantin
- Beltramello Olga
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- Bertella Claudia
- Bertoli Gabriele
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- Bertsche Carolyn
- Besjes Geert-Jan
- Bessidskaia Bylund Olga
- Bessner Martin
- Besson Nathalie
- Bethani Agni
- Bethke Siegfried
- Betti Alessandra
- Bevan Adrian
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- Bianchi Riccardo-Maria
- Biebel Otmar
- Biedermann Dustin
- Bielski Rafal
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- Bobbink Gerjan
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- Bocci Andrea
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- Bohm Christian
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- Borissov Guennadi
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- Bosman Martine
- Bossio Sola Jonathan
- Boudreau Joseph
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- Christodoulou Valentinos
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- Cuhadar Donszelmann Tulay
- Cukierman Aviv
- Cummings Jane
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- Cúth Jakub
- D'amen Gabriele
- D'Auria Saverio
- D'Eramo Louis
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- Da Via Cinzia
- Dabrowski Wladyslaw
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- de Asmundis Riccardo
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- De Kaushik
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- Yamaguchi Yohei
- Yamamoto Akira
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- Yamanaka Takashi
- Yamane Fumiya
- Yamatani Masahiro
- Yamazaki Tomohiro
- Yamazaki Yuji
- Yan Zhen
- Yang Haijun
- Yang Hongtao
- Yang Yi
- Yang Zongchang
- Yao Weiming
- Yap Yee
- Yasu Yoshiji
- Yatsenko Elena
- Yau Wong Kaven
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- Ye Shuwei
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- Yigitbasi Efe
- Yildirim Eda
- Yorita Kohei
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- Young Christopher
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- Yu Jie
- Yuen Stephanie
- Yusuff Imran
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- Zacharis Georgios
- Zaidan Remi
- Zaitsev Alexander
- Zakharchuk Nataliia
- Zalieckas Justas
- Zaman Aungshuman
- Zambito Stefano
- Zanzi Daniele
- Zeitnitz Christian
- Zemaityte Gabija
- Zemla Andrzej
- Zeng Jian
- Zeng Qi
- Zenin Oleg
- Zerwas Dirk
- Zhang Dengfeng
- Zhang Dongliang
- Zhang Fangzhou
- Zhang Guangyi
- Zhang Huijun
- Zhang Jinlong
- Zhang Lei
- Zhang Liqing
- Zhang Matt
- Zhang Peng
- Zhang Rui
- Zhang Ruiqi
- Zhang Xueyao
- Zhang Yu
- Zhang Zhiqing
- Zhao Xiandong
- Zhao Yongke
- Zhao Zhengguo
- Zhemchugov Alexey
- Zhou Bing
- Zhou Chen
- Zhou Li
- Zhou Maosen
- Zhou Mingliang
- Zhou Ning
- Zhou You
- Zhu Cheng
- Zhu Hongbo
- Zhu Junjie
- Zhu Yingchun
- Zhuang Xuai
- Zhukov Konstantin
- Zibell Andre
- Zieminska Daria
- Zimine Nikolai
- Zimmermann Christoph
- Zimmermann Stephanie
- Zinonos Zinonas
- Zinser Markus
- Ziolkowski Michael
- Zobernig Georg
- Zoccoli Antonio
- Zou Rui
- zur Nedden Martin
- Zwalinski Lukasz
- Åkesson Torsten
- Šfiligoj Tina
- Ženiš Tibor
- Živković Lidija
- Άlvarez Piqueras Damián
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2017
- Field of study
A search for weakly interacting massive particle dark matter produced in association with bottom or top quarks is presented. Final states containing third-generation quarks and miss- ing transverse momentum are considered. The analysis uses 36.1 fb−1 of proton–proton collision data recorded by the ATLAS experiment at √s = 13 TeV in 2015 and 2016. No significant excess of events above the estimated backgrounds is observed. The results are in- terpreted in the framework of simplified models of spin-0 dark-matter mediators. For colour- neutral spin-0 mediators produced in association with top quarks and decaying into a pair of dark-matter particles, mediator masses below 50 GeV are excluded assuming a dark-matter candidate mass of 1 GeV and unitary couplings. For scalar and pseudoscalar mediators produced in association with bottom quarks, the search sets limits on the production cross- section of 300 times the predicted rate for mediators with masses between 10 and 50 GeV and assuming a dark-matter mass of 1 GeV and unitary coupling. Constraints on colour- charged scalar simplified models are also presented. Assuming a dark-matter particle mass of 35 GeV, mediator particles with mass below 1.1 TeV are excluded for couplings yielding a dark-matter relic density consistent with measurements
Hyperoxemia and excess oxygen use in early acute respiratory distress syndrome : Insights from the LUNG SAFE study
- Author
- Abad Ricardo Diaz
- Abe Toshikazu
- Abroug Fekri
- Adams John C.
- Adamsson Richard O.
- Adolfsson Anne
- Aguilar Ronald Zumaran
- Aguirre Janet S.
- Aguirre-Bermeo Hernan
- Aisa Tharwat M.
- Aisiku Imo
- Ajetunmobi Olaitan O.
- Aker Mustafa
- Akyol Onat O.
- Al Dorzi Hasan M.
- Al Jabbary Ahmed S.
- Albaiceta Guillermo M.
- Albarrak Mohamad M.
- Albiero Daniela
- Alda Rosa S.
- Alejandro Risso V.
- Alexander Peter
- Algaba Ángela
- Aliaga Felipe A.
- Alisasis Alain U.
- Allan Russell M.
- Allue Raquel Montoiro
- Almekhlafi Ghaleb
- Alonso Javier G.
- Altaf Wahid
- Alvarez António M.
- Alvarez Javier
- Amin Pravin
- Amir Fahd
- Amor Abdellatif Benslama Mourad
- An Youzhong
- Andersen Finn H.
- Andoh Kohkichi
- Andruszkiewicz Pawel
- Aneman Anders
- Antonelli Massimo M.
- Antônio Ana Carolina P.
- Aoki Nobumasa
- Appelberg Henrik
- Arabi Yaasen
- Arabi Yaseen M.
- Araujo Ana M.
- Arizmendi Alfons
- Arnal Jean-Michel
- Artiga Maria Jose D.
- Artigas Antonio
- Ascoli Aline
- Au Siu-Ming
- Avila Luis E.
- Azad Raman
- Azevedo Luciano Cesar
- Baboi Loredana
- Badie Julio C.
- Bailey Irene M.
- Bailey Mathew B.
- Bajwa Ed
- Balkhi Hicham
- Baltus Thomas
- Banner-Goodspeed Valerie M.
- Barberet Guillaume
- Baron Rebecca M.
- Baronia Arvind K.
- Barratt-Due Andreas
- Barros Filipa M.
- Barros Nelson C.
- Batra Hitesh
- Battle Ceri E.
- Bauer Philippe R.
- Beck Eduardo
- Beck Oliver
- Bedreag Ovidiu H.
- Beegle Scott H.
- Beitler Jeremy R.
- Bellani Giacomo
- Bellani Giacomo
- Beloncle Francois
- Beraldo Daniel O.
- Berghe Caroline
- Berkelmans Frantz
- Besset Sebastien L.
- Bettini Lisandro R.
- Beuret Pascal
- Bezzi Marco G.
- Bhardwaj Vallish K.
- Bhowmick Kaushik
- Biehler Jerome
- Bigot Charlene
- Bihari Shailesh
- Biondi Rodrigo S.
- Biscione Roberto R.
- Bisso Mariano Carboni
- Black Colin S.
- Blakeman Thomas C.
- Bolon Stefan
- Borello Silvina A.
- Borotto Erika E.
- Botteri Marco
- Bouchoucha Slaheddine
- Boukhazna Messabi
- Bouw Maria J.
- Boyd Owen
- Bramall Jon
- Braschi Antonio
- Brazzi Luca
- Breen Dorothy M.
- Briquet Anais
- Brito Vania A.
- Brizuela Matias
- Brochard Laurent
- Brochard Laurent
- Broman Lars M.
- Brown Samuel M.
- Browne Troy S.
- Bruhn Alejandro R.
- Brunettini Barbara
- Bruns Monique M.
- Buensuseso Juan A.
- Bugedo Guillermo
- Buise Marc P.
- Bulpa Pierre A.
- Bumbasierevic Vesna
- Bumbasirevic Vesna
- Burtenshaw Andrew J.
- Burtin Philippe
- Buzancais Gautier
- Béduneau Gaetan
- Camsooksai Julie
- Canestrini Sergio
- Cani Alma
- Carbayo-Gorriz Cecilia
- Cardonnet Luis P.
- Careless Jon P.
- Carpentier Dorothée
- Carreño Nicolás G.
- Carteaux Guillaume
- Casalena Paolo
- Casement Jonathan
- Castro Alejandro G.
- Castro Silvia
- Catorze Nuno T.
- Cazorla-Barranquero Francisca G.
- Ceniceros-Barros Alexandra
- Cereijo Enrique
- Cerny Vladimir
- Cerrato Valeria I.
- Cervantes Mavy Ramirez
- Cesar Palazon Sanchez
- Ceunen Helga
- Ceylan Ilkay
- Chabanne Russell
- Chapman Rhiannon
- Chau Simon K.
- Chelly Jonathan
- Chen Kai
- Chena Ariel
- Cheng Meisy Perez
- Chiche Jean-Daniel
- Chouchene Imed
- Choudry Shazia
- Christiansen Aage
- Cimic Nedim
- Cinnella Gilda
- Cirone Rob
- Citalán Johanna E.
- Claraco-Vega Luis M.
- Clarkson Kevin
- Clarkson Kevin P.
- Claverias Laura
- Cohen Jason E.
- Cole Jade M.
- Collins Daniel V.
- Collyer Thomas
- Colombo Riccardo
- Combaux Daniele M.
- Combes Alain
- Cooper Raphael
- Coppadoro Andrea
- Corneci Dan E.
- Cortegiani Andrea
- Cortez Cesar A.
- Coxo Cristina M.
- Cracchiolo Andrea N.
- Cranshaw Julius H.
- Crapelli Giulia
- Crouch Daniel R.
- Crova Philippe J.
- Csabi Peter
- Curley Gerard
- Curto Elena Gallego
- Daldin Julio
- Dangers Laurence
- Danin Pierre-Eric
- Daubin C. dric
- Daviaud Fabrice
- Davies Kyle G.
- Dawson Heidi
- de Cima-Iglesias Sara
- de Gordoa Laura Ortiz-Ruiz
- de Haro Candelaria
- de Pablo Raul
- de Prost Nicolas
- Dean Michael N.
- Declercq Pierre-Louis M.
- Dector Dulce
- Dector Dulce M.
- Deicas Alberto
- del Carmen Lorente Maria
- Dellamonica Jean
- Dellera Christian
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- Ünal Necmettin
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2020
- Field of study
Publisher Copyright: © 2020 The Author(s). Copyright: Copyright 2020 Elsevier B.V., All rights reserved.Background: Concerns exist regarding the prevalence and impact of unnecessary oxygen use in patients with acute respiratory distress syndrome (ARDS). We examined this issue in patients with ARDS enrolled in the Large observational study to UNderstand the Global impact of Severe Acute respiratory FailurE (LUNG SAFE) study. Methods: In this secondary analysis of the LUNG SAFE study, we wished to determine the prevalence and the outcomes associated with hyperoxemia on day 1, sustained hyperoxemia, and excessive oxygen use in patients with early ARDS. Patients who fulfilled criteria of ARDS on day 1 and day 2 of acute hypoxemic respiratory failure were categorized based on the presence of hyperoxemia (PaO2 > 100 mmHg) on day 1, sustained (i.e., present on day 1 and day 2) hyperoxemia, or excessive oxygen use (FIO2 ≥ 0.60 during hyperoxemia). Results: Of 2005 patients that met the inclusion criteria, 131 (6.5%) were hypoxemic (PaO2 < 55 mmHg), 607 (30%) had hyperoxemia on day 1, and 250 (12%) had sustained hyperoxemia. Excess FIO2 use occurred in 400 (66%) out of 607 patients with hyperoxemia. Excess FIO2 use decreased from day 1 to day 2 of ARDS, with most hyperoxemic patients on day 2 receiving relatively low FIO2. Multivariate analyses found no independent relationship between day 1 hyperoxemia, sustained hyperoxemia, or excess FIO2 use and adverse clinical outcomes. Mortality was 42% in patients with excess FIO2 use, compared to 39% in a propensity-matched sample of normoxemic (PaO2 55-100 mmHg) patients (P = 0.47). Conclusions: Hyperoxemia and excess oxygen use are both prevalent in early ARDS but are most often non-sustained. No relationship was found between hyperoxemia or excessive oxygen use and patient outcome in this cohort. Trial registration: LUNG-SAFE is registered with ClinicalTrials.gov, NCT02010073publishersversionPeer reviewe
Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors
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- Abramova Liliya
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- Zeggini Eleftheria
- Zerwas Stephanie
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- Zhao Hongyu
- Zhou Hang
- Zillich Lea
- Zillich Lea
- Zipfel Stephan
- Zwart John-Anker
- Świątkowska Beata
- Świątkowska Beata
- Świątkowska Beata
- Publication venue
- Publication date
- 01/01/2021
- Field of study
Background Suicide is a leading cause of death worldwide, and nonfatal suicide attempts, which occur far more frequently, are a major source of disability and social and economic burden. Both have substantial genetic etiology, which is partially shared and partially distinct from that of related psychiatric disorders. Methods We conducted a genome-wide association study (GWAS) of 29,782 suicide attempt (SA) cases and 519,961 controls in the International Suicide Genetics Consortium (ISGC). The GWAS of SA was conditioned on psychiatric disorders using GWAS summary statistics via multitrait-based conditional and joint analysis, to remove genetic effects on SA mediated by psychiatric disorders. We investigated the shared and divergent genetic architectures of SA, psychiatric disorders, and other known risk factors. Results Two loci reached genome-wide significance for SA: the major histocompatibility complex and an intergenic locus on chromosome 7, the latter of which remained associated with SA after conditioning on psychiatric disorders and replicated in an independent cohort from the Million Veteran Program. This locus has been implicated in risk-taking behavior, smoking, and insomnia. SA showed strong genetic correlation with psychiatric disorders, particularly major depression, and also with smoking, pain, risk-taking behavior, sleep disturbances, lower educational attainment, reproductive traits, lower socioeconomic status, and poorer general health. After conditioning on psychiatric disorders, the genetic correlations between SA and psychiatric disorders decreased, whereas those with nonpsychiatric traits remained largely unchanged. Conclusions Our results identify a risk locus that contributes more strongly to SA than other phenotypes and suggest a shared underlying biology between SA and known risk factors that is not mediated by psychiatric disorders.Peer reviewe
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