Riesgo cardiometabólico en estudiantes de la carrera de nutrición y dietética

The cardiometabolic risk describes the probabilities of a person to suffer a heart or blood vessels damages. Hence the relevance of determining this type of risk in the students of the Nutrition and Dietetics career of the Technical University of Babahoyo. For this purpose, indicators such as waist circumference, waist/height formula, sex, body mass index, waist-height index ICE, physical activity and inductive-deductive method were measured in a population of 100 students. It was found that the predominant nutritional status in female students is overweight and obesity. This indicates that 29% of female students have an increased cardiovascular risk. With regard to cardiometabolic risk, it was determined that female students had a rate of 36%, compared with male students with 11%. Keywords: cardiometabolic risk factors, overweight, obesity. References [1]Organización Mundial de la Salud, «www.who.int. Non communicable diseases,» 2018. [Online]. Available: https://www.who.int/es/news-room/fact-sheets/detail/non-communicable-diseases. [Last access: August 25, 2021]. [2]J. Maldonado, C. Carranza, M. Ortiz, C. Gómez and N.Cortés, «Prevalencia de factores de riesgo caardiometabólico en estudiantes de la Universidad de la región centroocidental en la Universidad Michoacana San Nicolás de Hidalgo. México,» SCIELO, vol. 24, nº 2, pp. 78-86, 2013. [3]M. Morales, «Influence of phisical activity and nutritional habits on the risk of metabolic syndrome,» SCIELO, vol. 6, 2016. [4]G. Morales, T. Castillo, S. Muñoz, C. Belma, A. Soto, I. Schifferli and F. Guillén, «Asociación entre factores de riesgo cardiometabólicos, actividad física y sedentarismo, » Nutrición Hospitalaria, vol. 34, nº 6, pp. 1345-1352, 2017. [5]Organización Mundial de la Salud, «Obesidad y sobrepeso,» 2021. [Online]. Available: https://www.who.int/es/news-room/fact-sheets/detail/obesity-and-overweight. [Last access: August 29, 2021]. [6]G. Bray, G. Fruhbeck, D. Ryan and J. Wilding, «Management of obesity,» Lancet, vol. 387, nº 7, pp. 1847-1956, 2016. [7]A. Caicedo Paliz, A. León Fierro and K. Zambrano Llaguno, Protocolo de diagnóstico y manejo multidisciplinario de pacientes con sobrepeso y obesidad en la consulta ambulatoria, Quito: Universidad San Francisco de Quito, 2021. [8]INEC, «Encuesta Nacional de Salud y Nutrición (ENSANUT),» INEC, Quito, 2018. [9]N. Britto Núñez and R. Alcázar Carett, «Obesidad y riesgo cardiometabólico. Revisión.,» CIMEL, vol. 16, nº 2, pp. 106-113, 2011. [10]J. Vandervelde, H. Savelberg, N. Schaper and A. Koster, «Moderate activity and fitness not sedentary time are independently associated with cardiometabolic risks in US adults aged 18-49,» Environ Resident Public Health, vol. 12, pp. 2330-2343, 2015. [11]V. Carson and I. Janssen, «Volume, patterns and types of sedentary behavior and cardiometabolic health children and adolescents: a cross sectional study,» BMC Public Health, vol. 186, pp. 186-195, 2011. [12] T. Rendo Urteaga, A. De Moraes, T. Callesse y T. Marrios, «The combined effect of physical activity and sedentary behaviors on a clustered cardiometabolic risks score. The Helena Study,» Internal Cardiology, vol. 186, pp. 186-195, 2015. [13]R. Monroy Torres, C. Aguiklera Juarez and J. Nares, «Riesgo cardiometabólico en adolescentes con y sin obesidad: variables metabólicas, nutricionales y consumo de refresco,» revista Mexicana de trastornos Alimentarios, vol. 9, nº 1, pp. 24-33, 2018. [14]OMS, «estrategia Mundial sobre el régimen alimentario, actividad física y salud,» 2017. [Online]. Available: https://www.who.int/diethysicactivity/pa/es.[Last access: August 30, 2021]. [15]A. Alvarado Sánchez, A. González Yebra and M. Macías, «Correlaciones de factores de riesgo cardiometabólicio e hipoactividad con indice corporal y circunferencia de cintura en trabajadores del sector cuero y calzado de la ciudad de León,» Jóvenes en la ciencia, vol. 3, nº 2, pp. 1-5, 2017. [16]SEEDO, «Consenso SEEDO para la evaluación del sobrepeso y la obesidad. Revista Española de Obesidad, » 2007. [Online]. Available: https://www.seedo.es/images/site/documentacionConsenso/Consenso_SEEDO_2007 pdf. [Last access: August 21, 2021].El riesgo cardiometabólico describe las probabilidades de que una persona sufra un daño en el corazón o en los vasos sanguíneos. De allí la relevancia de determinar este tipo de riesgo en los estudiantes de la carrera de Nutrición y Dietética de la Universidad Técnica de Babahoyo. Para ello, se midieron indicadores como el perímetro de cintura, la fórmula cintura / talla, sexo, índice de masa corporal, índice cintura-estatura ICE, la actividad física y el método inductivo-deductivo, en una población de 100 estudiantes. Se encontró que el estado nutricional predominante en las estudiantes femeninas es el sobrepeso y la obesidad. Esto indica que un 29% de estudiantes femeninas tienen un riesgo cardiovascular aumentado. Con respecto al riesgo cardiometabólico, se determinó que las estudiantes femeninas tienen un índice de 36%, a diferencia de los estudiantes masculinos con un 11%. Palabras clave: factores de riesgo cardiometabólico, sobrepeso, obesidad. Referencias [1]Organización Mundial de la Salud, «www.who.int. Non communicable diseases,» 2018. [En línea]. Disponible en: https://www.who.int/es/news-room/fact-sheets/detail/non-communicable-diseases. [Último acceso: 25 agosto 2021]. [2]J. Maldonado, C. Carranza, M. Ortiz, C. Gómez y N.Cortés, «Prevalencia de factores de riesgo caardiometabólico en estudiantes de la Universidad de la regióncentroocidental en la Universidad Michoacana San Nicolás de Hidalgo. México,» SCIELO, vol. 24, nº 2, pp. 78-86, 2013. [3]M. Morales, «Influence of phisical activity and nutritional habits on the risk of metabolic syndrome,» SCIELO, vol. 6, 2016. [4]G. Morales, T. Castillo, S. Muñoz, C. Belma, A. Soto, I. Schifferli y F. Guillén, «Asociación entre factores de riesgo cardiometabólicos, actividad física y sedentarismo, » Nutrición Hospitalaria, vol. 34, nº 6, pp. 1345-1352, 2017. [5]Organización Mundial de la Salud, «Obesidad y sobrepeso,» 2021. [En línea]. Disponible en: https://www.who.int/es/news-room/fact-sheets/detail/obesity-and-overweight. [Último acceso: 29 agosto 2021]. [6]G. Bray, G. Fruhbeck, D. Ryan y J. Wilding, «Management of obesity,» Lancet, vol. 387, nº 7, pp. 1847-1956, 2016. [7]A. Caicedo Paliz, A. León Fierro y K. e. a. Zambrano Llaguno, Protocolo de diagnóstico y manejo multidisciplinario de pacientes con sobrepeso y obesidad en la consulta ambulatoria, Quito: Universidad San Francisco de Quito, 2021. [8]INEC, «Encuesta Nacional de Salud y Nutrición (ENSANUT),» INEC, Quito, 2018. [9]N. Britto Núñez y R. Alcázar Carett, «Obesidad y riesgo cardiometabólico. Revisión.,» CIMEL, vol. 16, nº 2, pp. 106-113, 2011. [10]J. Vandervelde, H. Savelberg, N. Schaper y A. Koster, «Moderate activity and fitness not sedentary time are independently associated with cardiometabolic risks in US adults aged 18-49,» Environ Resident Public Health, vol. 12, pp. 2330-2343, 2015. [11]V. carson y I. Janssen, «Volume, patterns and types of sedentary behavior and cardiometabolic health children and adolescents: a cross sectional study,» BMC Public Health, vol. 186, pp. 186-195, 2011. [12] T. rendo Urteaga, A. De Moraes, T. Callesse y T. e. a. Marrios, «The combined effect of physical activity and sedentary behaviors on a clustered cardiometabolic risks score. The Helena Study,» Internal Cardiology, vol. 186, pp. 186-195, 2015. [13]R. Monroy Torres, C. Aguiklera Juarez y J. Nares, «Riesgo cardiometabólico en adolescentes con y sin obesidad: variables metabólicas, nutricionales y consumo de refresco,» revista Mexicana de trastornos Alimentarios, vol. 9, nº 1, pp. 24-33, 2018. [14]OMS, «estrategia Mundial sobre el régimen alimentario, actividad física y salud,» 2017. [En línea]. Disponible en: https://www.who.int/diethysicactivity/pa/es.[Último acceso: 30 agosto 2021]. [15]A. Alvarado Sánchez, A. González Yebra y M. e. a. Macías, «Correlaciones de factores de riesgo cardiometabólicio e hipoactividad con indice corporal y circunferencia de cintura en trabajadores del sector cuero y calzado de la ciudad de León,» Jóvenes en la ciencia, vol. 3, nº 2, pp. 1-5, 2017. [16]SEEDO, «Consenso SEEDO para la evaluación del sobrepeso y la obesidad. Revista Española de Obesidad, » 2007. [En línea]. Disponible en: https://www.seedo.es/images/site/documentacionConsenso/Consenso_SEEDO_2007 pdf. [Último acceso: 21 agosto 2021]

Soluciones para mitigar los riesgos psicosociales del área administrativa de la empresa opción temporal y CÍA. S.A.S

Proponer soluciones efectivas que den desarrollo a las dimensiones de los riesgos psicosociales en la compañía Opción Temporal.Según el gerente de la compañía Opción temporal, poseen en el área administrativa un deterioro en la realización de las actividades laborales, por parte de los colaboradores que pueden estar asociados a los riesgos psicosociales, los cuales no han sido evaluados ni valorados dentro de la organización. Partiendo de lo anterior la investigación se encamina en buscar soluciones que mitiguen los riesgos psicosociales del área administrativa de la organización, por medio de la clasificación de los factores, medir los niveles e identificar el riesgo más alto en el área, y posterior a esto plantear herramientas por cada factor de riesgo clasificado e identificado, con el fin de disminuir el impacto negativo de los mismos. Esta investigación se realizó a través del enfoque mixto; esto hace descripciones de situaciones, personas e interacciones; como también se obtuvo información de datos concretos en porcentajes, por medio de un cuestionario estructurado, dando un alcance descriptivo que enmarca el estado del área administrativa de la empresa. Se clasificaron los tres factores de riesgo intra- laboral, extra-laboral y estrés por medio de la batería de riesgo psicosocial, se identificaron los niveles de los riesgos psicosociales propuestos por el cuestionario en donde se encontró que el riesgo de inseguridad contractual; tiene un nivel más alto que los demás. Por último, se diseñó un plan de acción con programas y actividades enfocadas a la disminución de cada uno de los factores de riesgo identificados en este proyecto. El análisis, realizado por cuatro especialistas en gerencia en SGSST en formación, concluyó en soluciones sobre en un plan de acción. En el desarrollo obtenido de la gestión, fue evidente que, para futuras investigaciones, será pertinente evaluar diferentes tipos de instrumentos y forma de recolección de información, y 11 tener en cuenta el resto de las áreas y personal de la compañía; así, de esta manera, tenemos datos más exactos y precisos para diseñar un plan de acción que sea aplicable a todos los niveles de la organización. Actualizar el SVE de acuerdo con las necesidades de los riesgos psicosociales y el seguimiento individual para prevenir y detectar futuras enfermedades laborales asociados a los riesgos psicosociales. Se definen los riesgos psicosociales son aspectos derivados de la interacción e influencia recíproca entre una organización, el ambiente y las personas, constituyéndose en agentes potencialmente nocivos para la salud mental y el desempeño de los trabajadores si no son controlados adecuadamente, por lo tanto, su existencia puede ser considerada como causa para la insatisfacción con el ambiente laboral, la organización del trabajo, la motivación y el bienestar integral, llegándose a establecer una relación cercana entre la percepción de los trabajadores hacia la empresa, la satisfacción laboral y los riesgos psicosociales.According to the manager of Temporary Option company, they have in to area administrative a deterioration in the performance of work activities, by employees who may be associated with psychosocial risks, with have not been evaluated or valued in the organization. In based on the foregoing, the investigation is aimed at finding solutions that mitigate the psychosocial risks of the administrative area of the organization, by middle of the classification of factors, measuring levels and identifying the highest risk in the area, after this, raise tools for each classified and identified risk factor, with order to reduce the negative impact. This research was carried out through the mixed approach; this makes descriptions of situations, people, and interactions; whit information was also obtained from specific data in percentages, by meddle of a structured questionnaire, giving a descriptive scope that frames the state of the company's administrative area. The three factors of intra-work, extra-work and stress risk were classified by means of the psychosocial risk battery. The levels of psychosocial risks proposed by the questionnaire were identified, where it was found that the risk of contractual insecurity; It has a higher level than the others. For last, an action plan was designed with programs and activities focused on reducing each of the risk factors identified in this project. The analysis, was carried out by four specialists in manager SGSST in formation, was concluded in solutions on an action plan. In the development obtained from the manage, it was evident that, for future investigations, it will be pertinent to assess different types of instruments and form of information collection, and as take into account the rest of the areas and the company's personnel; thus in this way have a more exact and precise data, in order to design an action plan that is applicable to all levels of the organization. Update the EVS according to the needs of psychosocial risks and the monitoring individually in order to prevent and detect future occupational diseases associated in the psychosocial risks. Psychosocial risks are defined as aspects derived from the interaction and reciprocal influence between an organization, the environment and people, becoming potentially harmful agents for mental health and the performance of workers if they are not adequately controlled, therefore, their existence can be considered as a cause for dissatisfaction with the work environment, work organization, motivation and comprehensive well-being, establishing a close relationship between the perception of workers towards the company, job satisfaction and psychosocial risks. Knowing the psychosocial risks in an organization allows determining the state of the same in terms of internal policies, work environment, organizational culture, mood and similar factors that can influence mental health and the performance of employees. This is important for a particular organization or process in determining whether its organizational management policies, strategies, and plans are truly effective

Soluciones para mitigar los riesgos psicosociales del área administrativa de la empresa opción temporal y CÍA. S.A.S

Proponer soluciones efectivas que den desarrollo a las dimensiones de los riesgos psicosociales en la compañía Opción Temporal.Según el gerente de la compañía Opción temporal, poseen en el área administrativa un deterioro en la realización de las actividades laborales, por parte de los colaboradores que pueden estar asociados a los riesgos psicosociales, los cuales no han sido evaluados ni valorados dentro de la organización. Partiendo de lo anterior la investigación se encamina en buscar soluciones que mitiguen los riesgos psicosociales del área administrativa de la organización, por medio de la clasificación de los factores, medir los niveles e identificar el riesgo más alto en el área, y posterior a esto plantear herramientas por cada factor de riesgo clasificado e identificado, con el fin de disminuir el impacto negativo de los mismos. Esta investigación se realizó a través del enfoque mixto; esto hace descripciones de situaciones, personas e interacciones; como también se obtuvo información de datos concretos en porcentajes, por medio de un cuestionario estructurado, dando un alcance descriptivo que enmarca el estado del área administrativa de la empresa. Se clasificaron los tres factores de riesgo intra- laboral, extra-laboral y estrés por medio de la batería de riesgo psicosocial, se identificaron los niveles de los riesgos psicosociales propuestos por el cuestionario en donde se encontró que el riesgo de inseguridad contractual; tiene un nivel más alto que los demás. Por último, se diseñó un plan de acción con programas y actividades enfocadas a la disminución de cada uno de los factores de riesgo identificados en este proyecto. El análisis, realizado por cuatro especialistas en gerencia en SGSST en formación, concluyó en soluciones sobre en un plan de acción. En el desarrollo obtenido de la gestión, fue evidente que, para futuras investigaciones, será pertinente evaluar diferentes tipos de instrumentos y forma de recolección de información, y 11 tener en cuenta el resto de las áreas y personal de la compañía; así, de esta manera, tenemos datos más exactos y precisos para diseñar un plan de acción que sea aplicable a todos los niveles de la organización. Actualizar el SVE de acuerdo con las necesidades de los riesgos psicosociales y el seguimiento individual para prevenir y detectar futuras enfermedades laborales asociados a los riesgos psicosociales. Se definen los riesgos psicosociales son aspectos derivados de la interacción e influencia recíproca entre una organización, el ambiente y las personas, constituyéndose en agentes potencialmente nocivos para la salud mental y el desempeño de los trabajadores si no son controlados adecuadamente, por lo tanto, su existencia puede ser considerada como causa para la insatisfacción con el ambiente laboral, la organización del trabajo, la motivación y el bienestar integral, llegándose a establecer una relación cercana entre la percepción de los trabajadores hacia la empresa, la satisfacción laboral y los riesgos psicosociales.According to the manager of Temporary Option company, they have in to area administrative a deterioration in the performance of work activities, by employees who may be associated with psychosocial risks, with have not been evaluated or valued in the organization. In based on the foregoing, the investigation is aimed at finding solutions that mitigate the psychosocial risks of the administrative area of the organization, by middle of the classification of factors, measuring levels and identifying the highest risk in the area, after this, raise tools for each classified and identified risk factor, with order to reduce the negative impact. This research was carried out through the mixed approach; this makes descriptions of situations, people, and interactions; whit information was also obtained from specific data in percentages, by meddle of a structured questionnaire, giving a descriptive scope that frames the state of the company's administrative area. The three factors of intra-work, extra-work and stress risk were classified by means of the psychosocial risk battery. The levels of psychosocial risks proposed by the questionnaire were identified, where it was found that the risk of contractual insecurity; It has a higher level than the others. For last, an action plan was designed with programs and activities focused on reducing each of the risk factors identified in this project. The analysis, was carried out by four specialists in manager SGSST in formation, was concluded in solutions on an action plan. In the development obtained from the manage, it was evident that, for future investigations, it will be pertinent to assess different types of instruments and form of information collection, and as take into account the rest of the areas and the company's personnel; thus in this way have a more exact and precise data, in order to design an action plan that is applicable to all levels of the organization. Update the EVS according to the needs of psychosocial risks and the monitoring individually in order to prevent and detect future occupational diseases associated in the psychosocial risks. Psychosocial risks are defined as aspects derived from the interaction and reciprocal influence between an organization, the environment and people, becoming potentially harmful agents for mental health and the performance of workers if they are not adequately controlled, therefore, their existence can be considered as a cause for dissatisfaction with the work environment, work organization, motivation and comprehensive well-being, establishing a close relationship between the perception of workers towards the company, job satisfaction and psychosocial risks. Knowing the psychosocial risks in an organization allows determining the state of the same in terms of internal policies, work environment, organizational culture, mood and similar factors that can influence mental health and the performance of employees. This is important for a particular organization or process in determining whether its organizational management policies, strategies, and plans are truly effective

INCLUSIÓN SOCIAL Y MARCA INSTITUCIONAL DESDE EL DEPORTE EN LA POLICÍA NACIONAL DE COLOMBIA

The present study describes and analyzes the development of links between sport, promotion of integration and social inclusion, and corporate image of the police institution, in the context of sports events between police, armed forces, institutions of higher education, and citizenship in recent years in Colombia. A descriptive research with a longitudinal design was carried out, using semi-structured interviews and referencing visits, focused on the role and impact that the National Police has through the use of sport as an element of integration, and considering the brand and image of the Police. The study shows that the promotion of sports practice and the establishment of strategic alliances between different entities are significant tools to promote human and social development, for integration and inclusion, and suggest actions to strengthen the corporate image and the achievement of institutional objectives that are pursued within the current national reality.El presente estudio describe y analiza el desarrollo de vínculos entre deporte, fomento de la integración e inclusión social, e imagen corporativa de la institución policial, en el contexto de eventos deportivos entre policía, fuerzas armadas, instituciones de educación superior, y ciudadanía, durante años recientes en Colombia. Se realizó una investigación de tipo descriptivo con diseño longitudinal, utilizando entrevistas semi-estructuradas y visitas de referenciación, enfocadas en el papel e impacto que la Policía Nacional tiene mediante el uso del deporte como elemento de integración, y considerando la marca e imagen de la Policía. El estudio muestra que la promoción de la práctica deportiva y el establecimiento de alianzas estratégicas entre distintas entidades, son herramientas significativas para fomentar el desarrollo humano y social, para la integración e inclusión, y permiten sugerir acciones para fortalecer la imagen corporativa y el logro de los objetivos institucionales que se persiguen dentro de la realidad nacional actual

Plasma and CSF biomarkers in a memory clinic: Head-to-head comparison of phosphorylated tau immunoassays

INTRODUCTION: Direct comparisons of the main blood phosphorylated tau immunoassays in memory clinic populations are needed to understand possible differences. METHODS: In the BIODEGMAR study, 197 participants presenting with cognitive complaints were classified into an Alzheimer's disease (AD) or a non-AD cerebrospinal fluid (CSF) profile group, according to their amyloid beta 42/ phosphorylated tau (Aβ42/p-tau) ratio. We performed a head-to-head comparison of nine plasma and nine CSF tau immunoassays and determined their accuracy to discriminate abnormal CSF Aβ42/p-tau ratio. RESULTS: All studied plasma tau biomarkers were significantly higher in the AD CSF profile group compared to the non-AD CSF profile group and significantly discriminated abnormal CSF Aβ42/p-tau ratio. For plasma p-tau biomarkers, the higher discrimination accuracy was shown by Janssen p-tau217 (r = 0.76; area under the curve [AUC] = 0.96), ADx p-tau181 (r = 0.73; AUC = 0.94), and Lilly p-tau217 (r = 0.73; AUC = 0.94). DISCUSSION: Several plasma p-tau biomarkers can be used in a specialized memory clinic as a stand-alone biomarker to detect biologically-defined AD. HIGHLIGHTS: Patients with an Alzheimer's disease cerebrospinal fluid (AD CSF) profile have higher plasma phosphorylated tau (p-tau) levels than the non-AD CSF profile group. All plasma p-tau biomarkers significantly discriminate patients with an AD CSF profile from the non-AD CSF profile group. Janssen p-tau217, ADx p-tau181, and Lilly p-tau217 in plasma show the highest accuracy to detect biologically defined AD. Janssen p-tau217, ADx p-tau181, Lilly p-tau217, Lilly p-tau181, and UGot p-tau231 in plasma show performances that are comparable to their CSF counterparts

Antimicrobial resistance among migrants in Europe: a systematic review and meta-analysis

BACKGROUND: Rates of antimicrobial resistance (AMR) are rising globally and there is concern that increased migration is contributing to the burden of antibiotic resistance in Europe. However, the effect of migration on the burden of AMR in Europe has not yet been comprehensively examined. Therefore, we did a systematic review and meta-analysis to identify and synthesise data for AMR carriage or infection in migrants to Europe to examine differences in patterns of AMR across migrant groups and in different settings. METHODS: For this systematic review and meta-analysis, we searched MEDLINE, Embase, PubMed, and Scopus with no language restrictions from Jan 1, 2000, to Jan 18, 2017, for primary data from observational studies reporting antibacterial resistance in common bacterial pathogens among migrants to 21 European Union-15 and European Economic Area countries. To be eligible for inclusion, studies had to report data on carriage or infection with laboratory-confirmed antibiotic-resistant organisms in migrant populations. We extracted data from eligible studies and assessed quality using piloted, standardised forms. We did not examine drug resistance in tuberculosis and excluded articles solely reporting on this parameter. We also excluded articles in which migrant status was determined by ethnicity, country of birth of participants' parents, or was not defined, and articles in which data were not disaggregated by migrant status. Outcomes were carriage of or infection with antibiotic-resistant organisms. We used random-effects models to calculate the pooled prevalence of each outcome. The study protocol is registered with PROSPERO, number CRD42016043681. FINDINGS: We identified 2274 articles, of which 23 observational studies reporting on antibiotic resistance in 2319 migrants were included. The pooled prevalence of any AMR carriage or AMR infection in migrants was 25·4% (95% CI 19·1-31·8; I2 =98%), including meticillin-resistant Staphylococcus aureus (7·8%, 4·8-10·7; I2 =92%) and antibiotic-resistant Gram-negative bacteria (27·2%, 17·6-36·8; I2 =94%). The pooled prevalence of any AMR carriage or infection was higher in refugees and asylum seekers (33·0%, 18·3-47·6; I2 =98%) than in other migrant groups (6·6%, 1·8-11·3; I2 =92%). The pooled prevalence of antibiotic-resistant organisms was slightly higher in high-migrant community settings (33·1%, 11·1-55·1; I2 =96%) than in migrants in hospitals (24·3%, 16·1-32·6; I2 =98%). We did not find evidence of high rates of transmission of AMR from migrant to host populations. INTERPRETATION: Migrants are exposed to conditions favouring the emergence of drug resistance during transit and in host countries in Europe. Increased antibiotic resistance among refugees and asylum seekers and in high-migrant community settings (such as refugee camps and detention facilities) highlights the need for improved living conditions, access to health care, and initiatives to facilitate detection of and appropriate high-quality treatment for antibiotic-resistant infections during transit and in host countries. Protocols for the prevention and control of infection and for antibiotic surveillance need to be integrated in all aspects of health care, which should be accessible for all migrant groups, and should target determinants of AMR before, during, and after migration. FUNDING: UK National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare Charity, the Wellcome Trust, and UK National Institute for Health Research Health Protection Research Unit in Healthcare-associated Infections and Antimictobial Resistance at Imperial College London

Search for new physics with same-sign isolated dilepton events with jets and missing transverse energy

A search for new physics is performed in events with two same-sign isolated leptons, hadronic jets, and missing transverse energy in the final state. The analysis is based on a data sample corresponding to an integrated luminosity of 4.98 inverse femtobarns produced in pp collisions at a center-of-mass energy of 7 TeV collected by the CMS experiment at the LHC. This constitutes a factor of 140 increase in integrated luminosity over previously published results. The observed yields agree with the standard model predictions and thus no evidence for new physics is found. The observations are used to set upper limits on possible new physics contributions and to constrain supersymmetric models. To facilitate the interpretation of the data in a broader range of new physics scenarios, information on the event selection, detector response, and efficiencies is provided.Comment: Published in Physical Review Letter

Search for a W' boson decaying to a bottom quark and a top quark in pp collisions at sqrt(s) = 7 TeV

Results are presented from a search for a W' boson using a dataset corresponding to 5.0 inverse femtobarns of integrated luminosity collected during 2011 by the CMS experiment at the LHC in pp collisions at sqrt(s)=7 TeV. The W' boson is modeled as a heavy W boson, but different scenarios for the couplings to fermions are considered, involving both left-handed and right-handed chiral projections of the fermions, as well as an arbitrary mixture of the two. The search is performed in the decay channel W' to t b, leading to a final state signature with a single lepton (e, mu), missing transverse energy, and jets, at least one of which is tagged as a b-jet. A W' boson that couples to fermions with the same coupling constant as the W, but to the right-handed rather than left-handed chiral projections, is excluded for masses below 1.85 TeV at the 95% confidence level. For the first time using LHC data, constraints on the W' gauge coupling for a set of left- and right-handed coupling combinations have been placed. These results represent a significant improvement over previously published limits.Comment: Submitted to Physics Letters B. Replaced with version publishe

Search for the standard model Higgs boson in the H to ZZ to 2l 2nu channel in pp collisions at sqrt(s) = 7 TeV

A search for the standard model Higgs boson in the H to ZZ to 2l 2nu decay channel, where l = e or mu, in pp collisions at a center-of-mass energy of 7 TeV is presented. The data were collected at the LHC, with the CMS detector, and correspond to an integrated luminosity of 4.6 inverse femtobarns. No significant excess is observed above the background expectation, and upper limits are set on the Higgs boson production cross section. The presence of the standard model Higgs boson with a mass in the 270-440 GeV range is excluded at 95% confidence level.Comment: Submitted to JHE