504 research outputs found
Paraphysical Jurisprudent Massacre Mediation
It is possible and thereby feasible to develop and implement a pragmatic methodology for a
preemptive evidentiary system of âParaphysical Jurisprudenceâ for mediating the occurrence of
massacres. A required comprehensive completion and formalizing of the tools of epistemology
(theory of knowledge) already exists and has been tested both ecumenically and scientifically. The
evolution of epistemology has followed the historical progression from myth and superstition to
logic and reason to empiricism and now finally to the utility of âtranscendenceâ as a tool in
knowledge acquisition. An inspiring example from popular culture is illustrated in the 2002
Hollywood film noir âMinority Reportâ designed by its director to present a âplausible future
worldâ for the year 2054 wherein an elaborate âPrecrime Unitâ is tested to prevent murder by
utilizing a trio of âprecogsâ bathed in a âphotonic milkâ able to presciently predetermine impending
occurrences of homicide for which the Precrime Police Unit then intervenes to prevent. Disdain
for a putative so-called scientific metaphysics by natural philosophers is deeply rooted in modern
pragmatic societies; perhaps rightly so as consistency, credibility and lack of a comprehensive
theory has been heretofore emphatically lacking. In addition to the major problem of repeatability
is the perceived distinction between domains of the physical and so-called âspiritualâ as mutually
exclusive. In this work a strong case is made for the rigorous viability and near term putative
implementation of a system of paraphysical jurisprudence drawing on the utility of a panoply of
concepts. The remaining question is when does feasible become practical in the face of a steady
increase in the heinous massacre of innocents
Application of double-cusp catastrophe theory to the physical evolution of qualia: Implications for paradigm shift in medicine and psychology
Seminal work intended to found a new field of integrative Noetic Science is summarized. Until now the
philosophy of Biological Mechanism has ruled medicine and psychology. Penrose claims, AA scientific world-view which
does not profoundly come to terms with the problem of conscious mind can have no serious pretensions of completeness@.
A noetic action principle synonymous with the historic concept of Ă©lan vital is introduced as the basis of a Continuous
State Conscious Universe (CSCU). The least unit of CSCU superspace defines Awareness as a fundamental physical
quantity like charge in electrodynamics. This cosmological context reveals the origin of complexity in self-organized
living-systems wherein the physical basis of qualia is formalized. The dynamics of this teleological action principle,
mediated by a unitary noetic field pervading all biochemical species, optimizes the state of well-being through
homeostasis and provides the fundamental basis for developing a Moral Psychology
Effective fisheries management instrumental in improving fish stock status
Marine fish stocks are an important part of the world food system and are particularly important for many of the poorest people of the world. Most existing analyses suggest overfishing is increasing, and there is widespread concern that fish stocks are decreasing throughout most of the world. We assembled trends in abundance and harvest rate of stocks that are scientifically assessed, constituting half of the reported globalmarine fish catch. For these stocks, on average, abundance is increasing and is at proposed target levels. Compared with regions that are intensively managed, regions with less-developed fisheries management have, on average, 3-fold greater harvest rates and half the abundance as assessed stocks. Available evidence suggests that the regions without assessments of abundance have little fisheries management, and stocks are in poor shape. Increased application of area-appropriate fisheries science recommendations and management tools are still needed for sustaining fisheries in places where they are lacking.Fil: Hilborn, Ray. University of Washington; Estados UnidosFil: Amoroso, Ricardo Oscar. University of Washington; Estados UnidosFil: Anderson, Christopher M.. University of Washington; Estados UnidosFil: Baum, Julia K.. University of Victoria; CanadĂĄFil: Branch, Trevor A.. University of Washington; Estados UnidosFil: Costello, Christopher. University of California at Santa Barbara; Estados UnidosFil: de Moor, Carryn L.. University of Cape Town; SudĂĄfricaFil: Faraj, Abdelmalek. Einstitut National de Recherche Halieutique; MarruecosFil: Hively, Daniel. University of Washington; Estados UnidosFil: Jensen, Olaf P.. Rutgers University; Estados UnidosFil: Kurota, Hiroyuki. Japan Fisheries Research and Education Agency; JapĂłnFil: Little, L. Richard. Csiro Oceans and Atmosphere; AustraliaFil: Mace, Pamela. Ministry for Primary Industries; Nueva ZelandaFil: McClanahan, Tim. Wildlife Conservation Society; Estados UnidosFil: Melnychuk, Michael C.. University of Washington; Estados UnidosFil: Minto, CĂłilĂn. Galway-Mayo Institute of Technology; IrlandaFil: Osio, Giacomo Chato. Joint Research Centre (JRC); Italia. DG Maritime Affairs and Fisheries, European Commission; BĂ©lgicaFil: Pons, Maite. University of Washington; Estados UnidosFil: Parma, Ana MarĂa. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro CientĂfico TecnolĂłgico Conicet - Centro Nacional PatagĂłnico. Centro para el Estudio de Sistemas Marinos; ArgentinaFil: Segurado, Susana. Sustainable Fisheries Partnership; Estados UnidosFil: Szuwalski, Cody S.. University of California at Santa Barbara; Estados UnidosFil: Wilson, Jono R.. University of California at Santa Barbara; Estados Unidos. The Nature Conservancy; Estados UnidosFil: Ye, Yimin. Food and Agriculture Organization of the United Nations; Itali
Preventive evidence into practice (PEP) study: implementation of guidelines to prevent primary vascular disease in general practice protocol for a cluster randomised controlled trial
There are significant gaps in the implementation and uptake of evidence-based guideline recommendations for cardiovascular disease (CVD) and diabetes in Australian general practice. This study protocol describes the methodology for a cluster randomised trial to evaluate the effectiveness of a model that aims to improve the implementation of these guidelines in Australian general practice developed by a collaboration between researchers, non-government organisations, and the profession.This study is funded by an Australian National Health and Medical Research
Council (NHMRC) Partnership grant (ID 568978) together with the Australian
National Heart Foundation, Royal Australian College of General Practitioners,
and the BUPA Foundation. MH is supported by a NHMRC Senior Principle
Research Fellowship
Fructose-driven glycolysis supports anoxia resistance in the naked mole-rat
The African naked mole-ratâs () social and subterranean lifestyle generates a hypoxic niche. Under experimental conditions, naked mole-rats tolerate hours of extreme hypoxia and survive 18 minutes of total oxygen deprivation (anoxia) without apparent injury. During anoxia, the naked mole-rat switches to anaerobic metabolism fueled by fructose, which is actively accumulated and metabolized to lactate in the brain. Global expression of the GLUT5 fructose transporter and high levels of ketohexokinase were identified as molecular signatures of fructose metabolism. Fructose-driven glycolytic respiration in naked mole-rat tissues avoids feedback inhibition of glycolysis via phosphofructokinase, supporting viability. The metabolic rewiring of glycolysis can circumvent the normally lethal effects of oxygen deprivation, a mechanism that could be harnessed to minimize hypoxic damage in human disease.Work was supported aEuropean Research Council (294678), the Deutsche Forschungsgemeinschaft SFB 665 and Go865/9-1, NSF (grant #0744979 ), NIH (grants HL71626 and HL606
Measurement of the W-boson mass in pp collisions at âs=7 TeV with the ATLAS detector
A measurement of the mass of the W boson is presented based on protonâproton collision data recorded in 2011 at a centre-of-mass energy of 7 TeV with the ATLAS detector at the LHC, and corresponding to 4.6 fbâ1 of integrated luminosity. The selected data sample consists of 7.8Ă106 candidates in the WâΌΜ channel and 5.9Ă106 candidates in the WâeÎœ channel. The W-boson mass is obtained from template fits to the reconstructed distributions of the charged lepton transverse momentum and of the W boson transverse mass in the electron and muon decay channels, yielding
mW=80370±7 (stat.)±11(exp. syst.)
±14(mod. syst.) MeV
=80370±19MeV,
where the first uncertainty is statistical, the second corresponds to the experimental systematic uncertainty, and the third to the physics-modelling systematic uncertainty. A measurement of the mass difference between the W+ and Wâbosons yields mW+âmWâ=â29±28 MeV
Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility
Report from Working Group 3: Beyond the standard model physics at the HL-LHC and HE-LHC
This is the third out of five chapters of the final report [1] of the Workshop on Physics at HL-LHC, and perspectives on HE-LHC [2]. It is devoted to the study of the potential, in the search for Beyond the Standard Model (BSM) physics, of the High Luminosity (HL) phase of the LHC, defined as ab of data taken at a centre-of-mass energy of 14 TeV, and of a possible future upgrade, the High Energy (HE) LHC, defined as ab of data at a centre-of-mass energy of 27 TeV. We consider a large variety of new physics models, both in a simplified model fashion and in a more model-dependent one. A long list of contributions from the theory and experimental (ATLAS, CMS, LHCb) communities have been collected and merged together to give a complete, wide, and consistent view of future prospects for BSM physics at the considered colliders. On top of the usual standard candles, such as supersymmetric simplified models and resonances, considered for the evaluation of future collider potentials, this report contains results on dark matter and dark sectors, long lived particles, leptoquarks, sterile neutrinos, axion-like particles, heavy scalars, vector-like quarks, and more. Particular attention is placed, especially in the study of the HL-LHC prospects, to the detector upgrades, the assessment of the future systematic uncertainties, and new experimental techniques. The general conclusion is that the HL-LHC, on top of allowing to extend the present LHC mass and coupling reach by on most new physics scenarios, will also be able to constrain, and potentially discover, new physics that is presently unconstrained. Moreover, compared to the HL-LHC, the reach in most observables will, generally more than double at the HE-LHC, which may represent a good candidate future facility for a final test of TeV-scale new physics
Study of doubly strange systems using stored antiprotons
Bound nuclear systems with two units of strangeness are still poorly known despite their importance for many strong interaction phenomena. Stored antiprotons beams in the GeV range represent an unparalleled factory for various hyperon-antihyperon pairs. Their outstanding large production probability in antiproton collisions will open the floodgates for a series of new studies of systems which contain two or even more units of strangeness at the PâŸANDA experiment at FAIR. For the first time, high resolution Îł-spectroscopy of doubly strange ÎÎ-hypernuclei will be performed, thus complementing measurements of ground state decays of ÎÎ-hypernuclei at J-PARC or possible decays of particle unstable hypernuclei in heavy ion reactions. High resolution spectroscopy of multistrange Îâ-atoms will be feasible and even the production of Ωâ-atoms will be within reach. The latter might open the door to the |S|=3 world in strangeness nuclear physics, by the study of the hadronic Ωâ-nucleus interaction. For the first time it will be possible to study the behavior of ÎâŸ+ in nuclear systems under well controlled conditions
TRY plant trait database â enhanced coverage and open access
Plant traits - the morphological, anatomical, physiological, biochemical and phenological characteristics of plants - determine how plants respond to environmental factors, affect other trophic levels, and influence ecosystem properties and their benefits and detriments to people. Plant trait data thus represent the basis for a vast area of research spanning from evolutionary biology, community and functional ecology, to biodiversity conservation, ecosystem and landscape management, restoration, biogeography and earth system modelling. Since its foundation in 2007, the TRY database of plant traits has grown continuously. It now provides unprecedented data coverage under an open access data policy and is the main plant trait database used by the research community worldwide. Increasingly, the TRY database also supports new frontiers of traitâbased plant research, including the identification of data gaps and the subsequent mobilization or measurement of new data. To support this development, in this article we evaluate the extent of the trait data compiled in TRY and analyse emerging patterns of data coverage and representativeness. Best species coverage is achieved for categorical traits - almost complete coverage for âplant growth formâ. However, most traits relevant for ecology and vegetation modelling are characterized by continuous intraspecific variation and traitâenvironmental relationships. These traits have to be measured on individual plants in their respective environment. Despite unprecedented data coverage, we observe a humbling lack of completeness and representativeness of these continuous traits in many aspects. We, therefore, conclude that reducing data gaps and biases in the TRY database remains a key challenge and requires a coordinated approach to data mobilization and trait measurements. This can only be achieved in collaboration with other initiatives
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