Reliability Study of c-Si PV Module Mounted on a Concrete Slab by Thermal Cycling Using Electroluminescence Scanning: Application in Future Solar Roadways

Several tests were conducted to ratify the reliability and durability of the solar photovoltaic (PV) devices before deployment in the real field (non-ideal conditions). In the real field, the temperature of the PV modules was varied during the day and night. Nowadays, people have been bearing in mind the deployment of PV modules on concrete roads to make use of the space accessible on roads. In this regard, a comparative study on the failure and degradation behaviors of crystalline Si PV modules with and without a concrete slab was executed via a thermal cycling stress test. The impact of the concrete slab on the performance degradation of PV modules was evaluated. Electroluminescence (EL) results showed that the defect due to thermal cycling (TC) stress was reduced in the PV module with a concrete slab. The power loss due to the thermal cycling was reduced by approximately 1% using a concrete slab for 200 cycles. The Rsh value was reduced to approximately 91% and 71% after thermal cycling of 200 cycles for reference PV modules, respectively. The value of I0 was increased to approximately 3.1 and 2.9 times the initial value for the PV modules without and with concrete, respectively. © 2020 by the authors.1

Water Distribution System Computer-Aided Design by Agent Swarm Optimization

Optimal design of water distribution systems (WDS), including the sizing of components, quality control, reliability, renewal and rehabilitation strategies, etc., is a complex problem in water engineering that requires robust methods of optimization. Classical methods of optimization are not well suited for analyzing highly-dimensional, multimodal, non-linear problems, especially given inaccurate, noisy, discrete and complex data. Agent Swarm Optimization (ASO) is a novel paradigm that exploits swarm intelligence and borrows some ideas from multiagent based systems. It is aimed at supporting decisionmaking processes by solving multi-objective optimization problems. ASO offers robustness through a framework where various population-based algorithms co-exist. The ASO framework is described and used to solve the optimal design of WDS. The approach allows engineers to work in parallel with the computational algorithms to force the recruitment of new searching elements, thus contributing to the solution process with expert-based proposals.This work has been developed with the support of the project IDAWAS, DPI2009-11591, of the Spanish Ministry of Education and Science, and ACOMP/2010/146 of the education department of the Generalitat Valenciana. The use of English was revised by John Rawlins.Montalvo Arango, I.; Izquierdo Sebastián, J.; Pérez García, R.; Herrera Fernández, AM. (2014). Water Distribution System Computer-Aided Design by Agent Swarm Optimization. Computer-Aided Civil and Infrastructure Engineering. 29(6):433-448. https://doi.org/10.1111/mice.12062S433448296Adeli, H., & Kumar, S. (1995). Distributed Genetic Algorithm for Structural Optimization. Journal of Aerospace Engineering, 8(3), 156-163. doi:10.1061/(asce)0893-1321(1995)8:3(156)Afshar, M. H., Akbari, M., & Mariño, M. A. (2005). 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(2011). Reliability and Tolerance Comparison in Water Supply Networks. Water Resources Management, 25(5), 1437-1448. doi:10.1007/s11269-010-9753-2Montalvo Arango, I. (s. f.). Diseño óptimo de sistemas de distribución de agua mediante Agent Swarm Optimization. doi:10.4995/thesis/10251/14858Montalvo, I., Izquierdo, J., Pérez-García, R., & Herrera, M. (2010). Improved performance of PSO with self-adaptive parameters for computing the optimal design of Water Supply Systems. Engineering Applications of Artificial Intelligence, 23(5), 727-735. doi:10.1016/j.engappai.2010.01.015Montalvo, I., Izquierdo, J., Pérez, R., & Iglesias, P. L. (2008). A diversity-enriched variant of discrete PSO applied to the design of water distribution networks. Engineering Optimization, 40(7), 655-668. doi:10.1080/03052150802010607Montalvo, I., Izquierdo, J., Pérez, R., & Tung, M. M. (2008). Particle Swarm Optimization applied to the design of water supply systems. 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Evaluation of Bone Marrow Adipose Tissue and Bone Mineralization on Broiler Chickens Affected by Wooden Breast Myopathy

In humans, alterations in bone metabolism have been associated with myopathies. We postulate the hypothesis that perhaps similar pathologies can also be associated in modern chickens. Hence, this study aimed to assess the fat infiltration in bone marrow and its repercussion on broiler chicken affected by Wooden Breast (WB) myopathy. Ten Cobb 500 live birds with extreme rigidity of the Pectoralis major (PM) muscle were selected as WB affected chickens by physical examination of the muscle at 49 days of age, whereas ten chickens healthy with no physical signs of hardness in the breast muscle were considered to be unaffected. Macroscopic lesions in affected chickens included areas of firm and inflamed muscle with pale appearance, hemorrhaging, and viscous exudate on the surface. Bone marrow and sections of the PM muscle were collected and analyzed for light microscopy. Additionally, transmission electron microscopy was conducted in affected or unaffected muscle. Chickens affected with WB showed significant reductions (P < 0.05) in femur diameter, calcium, and phosphorous percentage but increased breast weight, compression force and filet thickness when compared with non-affected chickens. Interestingly, bone marrow from WB chicken had subjectively, more abundant infiltration of adipose tissue, when compared with non-affected chickens. Histology of the Pectoralis major of birds with WB showed abundant infiltration of adipose tissue, muscle fibers degeneration with necrosis and infiltration of heterophils and mononuclear cells, connective tissue proliferation, and vasculitis. Ultrastructural changes of WB muscle revealed lack definition of bands in muscle tissue, or any normal ultrastructural anatomy such as myofibrils. The endomysium components were necrotic, and in some areas, the endomysium was notable only as a string of necrotic tissue between degraded myofibrils. The fascia appeared hypertrophied, with large areas of necrosis and myofiber without structural identity with degraded mitochondria adjacent to the disrupted muscle tissue. As far as we know, this is the first study that describes a subjective increase in adipose tissue in the bone marrow of chickens affected with WB when compared with non-affected chickens, and reduced bone mineralization

Gametogenesis in the Pacific Oyster Crassostrea gigas: A Microarrays-Based Analysis Identifies Sex and Stage Specific Genes

Background: The Pacific oyster Crassostrea gigas (Mollusca, Lophotrochozoa) is an alternative and irregular protandrous hermaphrodite: most individuals mature first as males and then change sex several times. Little is known about genetic and phenotypic basis of sex differentiation in oysters, and little more about the molecular pathways regulating reproduction. We have recently developed and validated a microarray containing 31,918 oligomers (Dheilly et al., 2011) representing the oyster transcriptome. The application of this microarray to the study of mollusk gametogenesis should provide a better understanding of the key factors involved in sex differentiation and the regulation of oyster reproduction. Methodology/Principal Findings: Gene expression was studied in gonads of oysters cultured over a yearly reproductive cycle. Principal component analysis and hierarchical clustering showed a significant divergence in gene expression patterns of males and females coinciding with the start of gonial mitosis. ANOVA analysis of the data revealed 2,482 genes differentially expressed during the course of males and/or females gametogenesis. The expression of 434 genes could be localized in either germ cells or somatic cells of the gonad by comparing the transcriptome of female gonads to the transcriptome of stripped oocytes and somatic tissues. Analysis of the annotated genes revealed conserved molecular mechanisms between mollusks and mammals: genes involved in chromatin condensation, DNA replication and repair, mitosis and meiosis regulation, transcription, translation and apoptosis were expressed in both male and female gonads. Most interestingly, early expressed male-specific genes included bindin and a dpy-30 homolog and female-specific genes included foxL2, nanos homolog 3, a pancreatic lipase related protein, cd63 and vitellogenin. Further functional analyses are now required in order to investigate their role in sex differentiation in oysters. Conclusions/Significance: This study allowed us to identify potential markers of early sex differentiation in the oyster C. gigas, an alternative hermaphrodite mollusk. We also provided new highly valuable information on genes specifically expressed by mature spermatozoids and mature oocytes

Redox modulation of muscle mass and function

Muscle mass and strength are very important for exercise performance. Training-induced musculoskeletal injuries usually require periods of complete immobilization to prevent any muscle contraction of the affected muscle groups. Disuse muscle wasting will likely affect every sport practitioner in his or her lifetime. Even short periods of disuse results in significant declines in muscle size, fiber cross sectional area, and strength. To understand the molecular signaling pathways involved in disuse muscle atrophy is of the utmost importance to develop more effective countermeasures in sport science research. We have divided our review in four different sections. In the first one we discuss the molecular mechanisms involved in muscle atrophy including the main protein synthesis and protein breakdown signaling pathways. In the second section of the review we deal with the main cellular, animal, and human atrophy models. The sources of reactive oxygen species in disuse muscle atrophy and the mechanism through which they regulate protein synthesis and proteolysis are reviewed in the third section of this review. The last section is devoted to the potential interventions to prevent muscle disuse atrophy with especial consideration to studies on which the levels of endogenous antioxidants enzymes or dietary antioxidants have been tested

A call for action to the biomaterial community to tackle antimicrobial resistance

The global surge of antimicrobial resistance (AMR) is a major concern for public health and proving to be a key challenge in modern disease treatment, requiring action plans at all levels. Microorganisms regularly and rapidly acquire resistance to antibiotic treatments and new drugs are continuously required. However, the inherent cost and risk to develop such molecules has resulted in a drying of the pipeline with very few compounds currently in development. Over the last two decades, efforts have been made to tackle the main sources of AMR. Nevertheless, these require the involvement of large governmental bodies, further increasing the complexity of the problem. As a group with a long innovation history, the biomaterials community is perfectly situated to push forward novel antimicrobial technologies to combat AMR. Although this involvement has been felt, it is necessary to ensure that the field offers a united front with special focus in areas that will facilitate the development and implementation of such systems. This paper reviews state of the art biomaterials strategies striving to limit AMR. Promising broad-spectrum antimicrobials and device modifications are showcased through two case studies for different applications, namely topical and implantables, demonstrating the potential for a highly efficacious physical and chemical approach. Finally, a critical review on barriers and limitations of these methods has been developed to provide a list of short and long-term focus areas in order to ensure the full potential of the biomaterials community is directed to helping tackle the AMR pandemic