Review and Techno-Economic Analysis of Emerging Thermo-Mechanical Energy Storage Technologies

Thermo-mechanical energy storage can be a cost-effective solution to provide flexibility and balance highly renewable energy systems. Here, we present a concise review of emerging thermo-mechanical energy storage solutions focusing on their commercial development. Under a unified framework, we review technologies that have proven to work conceptually through project demonstration at a scale above 1 MW by describing the current state of commercial development, quantifying techno-economic parameters, outlining the challenges, and assessing each technology’s potential for commercial viability. The levelized cost of storage for thermo-mechanical energy storage at storage duration between 8 h and 1 week is cheaper than that of lithium-ion batteries and hydrogen storage; however, energy storage for such duration does not pay for itself at the current renewable penetration levels. For medium-term energy storage to be viable, at the realistic storage cost of 15 USD/kWh to 40 USD/kWh, the investment cost for power components should decrease to one-fifth of the current costs. Thermo-mechanical energy storage can be economically viable at the current investment costs in off-grid systems only when the marginal cost of alternative fuel exceeds 100 USD/MWh. We identified the cost ratio (charge power cost/discharge power cost) and the discharge efficiency as the critical technology-related performance parameters. Other external factors such as wind and solar fractions, demand, interconnections, sector coupling, and market structure play an important role in determining the economic feasibility of thermo-mechanical energy storage

Review and Techno-Economic Analysis of Emerging Thermo-Mechanical Energy Storage Technologies

Thermo-mechanical energy storage can be a cost-effective solution to provide flexibility and balance highly renewable energy systems. Here, we present a concise review of emerging thermo-mechanical energy storage solutions focusing on their commercial development. Under a unified framework, we review technologies that have proven to work conceptually through project demonstration at a scale above 1 MW by describing the current state of commercial development, quantifying techno-economic parameters, outlining the challenges, and assessing each technology’s potential for commercial viability. The levelized cost of storage for thermo-mechanical energy storage at storage duration between 8 h and 1 week is cheaper than that of lithium-ion batteries and hydrogen storage; however, energy storage for such duration does not pay for itself at the current renewable penetration levels. For medium-term energy storage to be viable, at the realistic storage cost of 15 USD/kWh to 40 USD/kWh, the investment cost for power components should decrease to one-fifth of the current costs. Thermo-mechanical energy storage can be economically viable at the current investment costs in off-grid systems only when the marginal cost of alternative fuel exceeds 100 USD/MWh. We identified the cost ratio (charge power cost/discharge power cost) and the discharge efficiency as the critical technology-related performance parameters. Other external factors such as wind and solar fractions, demand, interconnections, sector coupling, and market structure play an important role in determining the economic feasibility of thermo-mechanical energy storage

Heparanase powers a chronic inflammatory circuit that promotes colitis-associated tumorigenesis in mice

Ulcerative colitis (UC) is a chronic inflammatory bowel disease that is closely associated with colon cancer. Expression of the enzyme heparanase is clearly linked to colon carcinoma progression, but its role in UC is unknown. Here we demonstrate for what we believe to be the first time the importance of heparanase in sustaining the immune-epithelial crosstalk underlying colitis-associated tumorigenesis. Using histological specimens from UC patients and a mouse model of dextran sodium sulfate–induced colitis, we found that heparanase was constantly overexpressed and activated throughout the disease. We demonstrate, using heparanase-overexpressing transgenic mice, that heparanase overexpression markedly increased the incidence and severity of colitis-associated colonic tumors. We found that highly coordinated interactions between the epithelial compartment (contributing heparanase) and mucosal macrophages preserved chronic inflammatory conditions and created a tumor-promoting microenvironment characterized by enhanced NF-κB signaling and induction of STAT3. Our results indicate that heparanase generates a vicious cycle that powers colitis and the associated tumorigenesis: heparanase, acting synergistically with the intestinal flora, stimulates macrophage activation, while macrophages induce production (via TNF-α–dependent mechanisms) and activation (via secretion of cathepsin L) of heparanase contributed by the colon epithelium. Thus, disruption of the heparanase-driven chronic inflammatory circuit is highly relevant to the design of therapeutic interventions in colitis and the associated cancer

Kreislaufstillstand unter besonderen Umständen: Elektrolytstörungen, Vergiftungen, Ertrinken, Unter-kühlung, Hitzekrankheit, Asthma, Anaphylaxie, Herzchirurgie, Trauma, Schwangerschaft, Stromunfall

Soar J, Perkins GD, Abbas G, et al. European Resuscitation Council Guidelines for Resuscitation 2010 Section 8. Cardiac arrest in special circumstances: Electrolyte abnormalities, poisoning, drowning, accidental hypothermia, hyperthermia, asthma, anaphylaxis, cardiac surgery, trauma, pregnancy, electrocution. Resuscitation. 2010;81(10):1400-1433