A practitioner concept of contemporary creativity

This article reviews conceptualisations from three academic areas: the sociology of art, the psychology of creativity, and research on the cultural and creative industries. These are compared with findings from a critical discursive study with UK practitioners. The meanings and associations these ‘maker artists’ attach to creativity are discussed as a ‘practitioner concept’. For the practitioners, the association of creativity with art carries a promise of transcendence and escape from ordinary life, but also a potential challenge to their own entitlement and claims to a creative status. The article shows, first, that the academic areas utilise different and conflicting conceptualisations and, second, that the practitioner concept is not consistent with any one of these. The article argues that the contemporary celebration of creativity is based on different meanings and unacknowledged conflicts. The article proposes that future social psychological research on creativity requires a more critical approach to the concept

The Public Health Response and Epidemiologic Investigation Related to the Opening of a Bacillus anthracis–Containing Envelope, Capitol Hill, Washington, D.C.

On October 15, 2001, a U.S. Senate staff member opened an envelope containing Bacillus anthracis spores. Chemoprophylaxis was promptly initiated and nasal swabs obtained for all persons in the immediate area. An epidemiologic investigation was conducted to define exposure areas and identify persons who should receive prolonged chemoprophylaxis, based on their exposure risk. Persons immediately exposed to B. anthracis spores were interviewed; records were reviewed to identify additional persons in this area. Persons with positive nasal swabs had repeat swabs and serial serologic evaluation to measure antibodies to B. anthracis protective antigen (anti-PA). A total of 625 persons were identified as requiring prolonged chemoprophylaxis; 28 had positive nasal swabs. Repeat nasal swabs were negative at 7 days; none had developed anti-PA antibodies by 42 days after exposure. Early nasal swab testing is a useful epidemiologic tool to assess risk of exposure to aerosolized B. anthracis. Early, wide chemoprophylaxis may have averted an outbreak of anthrax in this population

Special issue conclusion : The GLES Open Science Challenge 2021 in hindsight: experiences gained and lessons learned

Die GLES Open Science Challenge 2021 ist ein Pilotprojekt, das zeigt, dass Registered Reports ein geeignetes und gewinnbringendes Publikationsformat in der quantitativen Politikwissenschaft sind, die dazu beitragen können, die Transparenz und Replizierbarkeit im Forschungsprozess zu erhöhen und somit substanzielle und relevante Beiträge für unsere Disziplin zu liefern. Das Ergebnis ist die Veröffentlichung dieses Sonderheftes mit sieben Registered Reports, die auf Daten der German Longitudinal Election Study (GLES) basieren, die im Rahmen der Bundestagswahl 2021 erhoben wurden. Dieser abschließende Artikel des Sonderheftes bringt die Perspektiven von Autor*innen, Gutachter*innen, Organisator*innen und Herausgeber*innen zusammen, um eine Bilanz der verschiedenen Erfahrungen und Lehren zu ziehen, die im Laufe dieses Projektes gewonnen wurden

Source of oceanic magnetic anomalies and the geomagnetic polarity time scale

Marine magnetic anomalies provide the framework for the geomagnetic polarity timescale for the Late Jurassic to Recent (since 160 Ma). Magnetostratigraphic records confirm that the polarity reversal sequence interpreted from magnetic anomalies is complete to a resolution of better than 30 ky. In addition to this record of polarity reversals, magnetic anomalies also appear to preserve information on geomagnetic intensity fluctuations. The correspondence of coherent near-bottom anomaly variations with independent estimates of field intensity provides strong evidence that geomagnetic intensity modulates the magnetization of the ocean crust. Indeed, many short wavelength anomaly variations in sea-surface magnetic profiles over fast-spreading ridges are likely attributable to geomagnetic intensity variations. Although longer-term geomagnetic field behavior may also be reflected in anomaly amplitudes, documenting such a signal requires a better understanding of time-dependent changes in the magnetic source (e.g., from low-temperature alteration) that may also affect magnetic anomalies. The extrusive layer, with an average remanence of ∼ 5 A m−1, is the largest contributor to magnetic anomalies. However, enhanced sampling of oceanic gabbros (average remanence ∼ 1 A m−1) and, to a lesser extent, dikes (average remanence ∼ 2 A m−1) reveals that these deeper (and thicker) layers likely generate anomalies comparable to those from the lavas. Lava accumulation at intermediate- and fast-spreading ridges typically occurs over a narrow (1–3 km) region and dike emplacement is even more narrowly confined, resulting in a relatively high fidelity record of geomagnetic field behavior. The slow cooling of the gabbroic layer, however, results in gently dipping polarity boundaries that significantly affect the skewness of the resulting anomalies, which is also a sensitive measure of net rotations of the source layer(s). The magnetizations of the dikes and gabbros are characterized by high stability and are not expected to significantly change with time, although there are insufficient data to confirm this. The lavas, however, typically show evidence of low-temperature alteration, which has been long regarded as a process that progressively reduces the magnetization (and degrades the geomagnetic signal) in the extrusive layer and reduces the amplitude of magnetic anomalies. Sufficient data have become available to examine this conventional wisdom. There is a substantial (∼ 4x) reduction in magnetization from on-axis samples to immediately off-axis drillsites (∼ 0.5 My), but little further change in half-dozen or so deep crustal sites to ∼ 160 Ma. High paleointensity that characterizes the last few thousand years may contribute significantly to the high on-axis magnetization. The task of evaluating changes in remanence of the extrusive layer is made more difficult by substantial cooling-rate-dependent changes in magnetic properties and the systematic variation in remanence with iron content (magnetic telechemistry). The commonly cited magnetic anomaly amplitude envelope is in fact not systematically observed – the Central Anomaly is elevated at slow-spreading ridges but is not as prominent at faster spreading rates. Nonetheless, magnetic anomaly amplitudes are consistent with magnetization change is poorly constrained. Direct determinations of the degree of low-temperature oxidation reveal the presence of highly oxidized titanomagnetite in samples less than 1 My old, suggesting a short (∼ 105 years) time constant though the effects of low-temperature oxidation are quite heterogeneous. While low-temperature oxidation does have some affect on lava magnetization and anomaly amplitudes, there is increasing evidence that marine magnetic anomalies are capable of recording a broad spectrum of geomagnetic field behavior, ranging from millennial-scale paleointensity variations to polarity reversals to apparent polar wander to, more speculatively, long-term changes in average field strength. Several emerging tools and approaches – autonomous vehicles, oriented samples, absolute paleointensity of near-ridge lavas, and measurements of the vector anomalous field – are therefore likely to significantly advance our understanding of the geomagnetic signal recorded in the oceanic crust, as well as our ability to utilize this information in addressing outstanding problems in crustal accretion processes

Global, regional, and national burden of neurological disorders, 1990–2016 : a systematic analysis for the Global Burden of Disease Study 2016

Background: Neurological disorders are increasingly recognised as major causes of death and disability worldwide. The aim of this analysis from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2016 is to provide the most comprehensive and up-to-date estimates of the global, regional, and national burden from neurological disorders. Methods: We estimated prevalence, incidence, deaths, and disability-adjusted life-years (DALYs; the sum of years of life lost [YLLs] and years lived with disability [YLDs]) by age and sex for 15 neurological disorder categories (tetanus, meningitis, encephalitis, stroke, brain and other CNS cancers, traumatic brain injury, spinal cord injury, Alzheimer's disease and other dementias, Parkinson's disease, multiple sclerosis, motor neuron diseases, idiopathic epilepsy, migraine, tension-type headache, and a residual category for other less common neurological disorders) in 195 countries from 1990 to 2016. DisMod-MR 2.1, a Bayesian meta-regression tool, was the main method of estimation of prevalence and incidence, and the Cause of Death Ensemble model (CODEm) was used for mortality estimation. We quantified the contribution of 84 risks and combinations of risk to the disease estimates for the 15 neurological disorder categories using the GBD comparative risk assessment approach. Findings: Globally, in 2016, neurological disorders were the leading cause of DALYs (276 million [95% UI 247–308]) and second leading cause of deaths (9·0 million [8·8–9·4]). The absolute number of deaths and DALYs from all neurological disorders combined increased (deaths by 39% [34–44] and DALYs by 15% [9–21]) whereas their age-standardised rates decreased (deaths by 28% [26–30] and DALYs by 27% [24–31]) between 1990 and 2016. The only neurological disorders that had a decrease in rates and absolute numbers of deaths and DALYs were tetanus, meningitis, and encephalitis. The four largest contributors of neurological DALYs were stroke (42·2% [38·6–46·1]), migraine (16·3% [11·7–20·8]), Alzheimer's and other dementias (10·4% [9·0–12·1]), and meningitis (7·9% [6·6–10·4]). For the combined neurological disorders, age-standardised DALY rates were significantly higher in males than in females (male-to-female ratio 1·12 [1·05–1·20]), but migraine, multiple sclerosis, and tension-type headache were more common and caused more burden in females, with male-to-female ratios of less than 0·7. The 84 risks quantified in GBD explain less than 10% of neurological disorder DALY burdens, except stroke, for which 88·8% (86·5–90·9) of DALYs are attributable to risk factors, and to a lesser extent Alzheimer's disease and other dementias (22·3% [11·8–35·1] of DALYs are risk attributable) and idiopathic epilepsy (14·1% [10·8–17·5] of DALYs are risk attributable). Interpretation: Globally, the burden of neurological disorders, as measured by the absolute number of DALYs, continues to increase. As populations are growing and ageing, and the prevalence of major disabling neurological disorders steeply increases with age, governments will face increasing demand for treatment, rehabilitation, and support services for neurological disorders. The scarcity of established modifiable risks for most of the neurological burden demonstrates that new knowledge is required to develop effective prevention and treatment strategies. Funding: Bill & Melinda Gates Foundation

Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

Background: In an era of shifting global agendas and expanded emphasis on non-communicable diseases and injuries along with communicable diseases, sound evidence on trends by cause at the national level is essential. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) provides a systematic scientific assessment of published, publicly available, and contributed data on incidence, prevalence, and mortality for a mutually exclusive and collectively exhaustive list of diseases and injuries. Methods: GBD estimates incidence, prevalence, mortality, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life-years (DALYs) due to 369 diseases and injuries, for two sexes, and for 204 countries and territories. Input data were extracted from censuses, household surveys, civil registration and vital statistics, disease registries, health service use, air pollution monitors, satellite imaging, disease notifications, and other sources. Cause-specific death rates and cause fractions were calculated using the Cause of Death Ensemble model and spatiotemporal Gaussian process regression. Cause-specific deaths were adjusted to match the total all-cause deaths calculated as part of the GBD population, fertility, and mortality estimates. Deaths were multiplied by standard life expectancy at each age to calculate YLLs. A Bayesian meta-regression modelling tool, DisMod-MR 2.1, was used to ensure consistency between incidence, prevalence, remission, excess mortality, and cause-specific mortality for most causes. Prevalence estimates were multiplied by disability weights for mutually exclusive sequelae of diseases and injuries to calculate YLDs. We considered results in the context of the Socio-demographic Index (SDI), a composite indicator of income per capita, years of schooling, and fertility rate in females younger than 25 years. Uncertainty intervals (UIs) were generated for every metric using the 25th and 975th ordered 1000 draw values of the posterior distribution. Findings: Global health has steadily improved over the past 30 years as measured by age-standardised DALY rates. After taking into account population growth and ageing, the absolute number of DALYs has remained stable. Since 2010, the pace of decline in global age-standardised DALY rates has accelerated in age groups younger than 50 years compared with the 1990–2010 time period, with the greatest annualised rate of decline occurring in the 0–9-year age group. Six infectious diseases were among the top ten causes of DALYs in children younger than 10 years in 2019: lower respiratory infections (ranked second), diarrhoeal diseases (third), malaria (fifth), meningitis (sixth), whooping cough (ninth), and sexually transmitted infections (which, in this age group, is fully accounted for by congenital syphilis; ranked tenth). In adolescents aged 10–24 years, three injury causes were among the top causes of DALYs: road injuries (ranked first), self-harm (third), and interpersonal violence (fifth). Five of the causes that were in the top ten for ages 10–24 years were also in the top ten in the 25–49-year age group: road injuries (ranked first), HIV/AIDS (second), low back pain (fourth), headache disorders (fifth), and depressive disorders (sixth). In 2019, ischaemic heart disease and stroke were the top-ranked causes of DALYs in both the 50–74-year and 75-years-and-older age groups. Since 1990, there has been a marked shift towards a greater proportion of burden due to YLDs from non-communicable diseases and injuries. In 2019, there were 11 countries where non-communicable disease and injury YLDs constituted more than half of all disease burden. Decreases in age-standardised DALY rates have accelerated over the past decade in countries at the lower end of the SDI range, while improvements have started to stagnate or even reverse in countries with higher SDI. Interpretation: As disability becomes an increasingly large component of disease burden and a larger component of health expenditure, greater research and developm nt investment is needed to identify new, more effective intervention strategies. With a rapidly ageing global population, the demands on health services to deal with disabling outcomes, which increase with age, will require policy makers to anticipate these changes. The mix of universal and more geographically specific influences on health reinforces the need for regular reporting on population health in detail and by underlying cause to help decision makers to identify success stories of disease control to emulate, as well as opportunities to improve. Funding: Bill & Melinda Gates Foundation. © 2020 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 licens