Pd(NHC)(μ-Cl)Cl]2: Versatile and Highly Reactive Complexes for Cross-Coupling Reactions that Avoid Formation of Inactive Pd(I) Off-Cycle Products

Data related to the figures, diagrams and tables of the published article in iScience, 2020, 23 (8), p.101377. The archives correspond on the one hand, to a document with the complementary information of the transparent methods of figures S1-S113, schemes S1-S8 and tables S1 and S2 of the article published in iScience, 2020, 23 (8), p.101377 and on the other hand, a file with cartesian coordinate data and energies related to Figure 4. DFT-Optimized Pathway (Relative Energies to Pd (0) in kcal / mol) for the Activation of Catalysts 6, 11), and 12 6 = IPr, 11 = SIPr, 12 = IPr *, [Pd (NHC) (m-Cl) Cl] 2 from the same published article mentioned abov

Responses of microbial activity in hyporheic pore water to biogeochemical changes in a drying headwater stream

1. Microbial heterotrophic activity is a major driver of nutrient and organic matter processing in the hyporheic zone of headwater streams. Additionally, the hyporheic zone might provide refuge for microbes when surface flow ceases during drought events. 2. We investigated chemical (organic and inorganic nutrients) and microbiological parameters (bacterial cell concentration, live–dead ratios, and extracellular enzyme activities) of surface and interstitial pore water in a period of progressive surface‐hyporheic disconnection due to summer drying. The special situation of the chosen study reach, where groundwater mixing is impeded by the bedrock forming a natural channel filled with sediment, allowed as to study the transformation of these parameters along hyporheic flow paths. 3. The chemical composition of the hyporheic pore water reflected the connectivity with the surface water, as expressed in the availability of nitrate and oxygen. Conversely, microbiological parameters in all hyporheic locations were different from the surface waters, suggesting that the microbial activity in the water changes rapidly once the water enters the hyporheic zone. This feature was principally manifested in higher live–dead ratios and lower leucine aminopeptidase (an activity related to nitrogen acquisition) in the hyporheic pore waters. 4. Overall, bacterial cell concentration and extracellular enzyme activities increased along hyporheic flow paths, with a congruent decrease in inorganic nutrients and dissolved organic matter quantity and apparent molecular size. 5. Our findings show two important functions of the hyporheic zone during drought: (1) deeper (−50 cm) water‐saturated layers can act as a refuge for microbial activity; and (2) the hyporheic zone shows high rates of carbon and nitrogen turnover when water residence times are longer during drought. These rates might be even enhanced by an increase in living microbes in the remaining moist locations of the hyporheic zone.© 2019 The Author

Database: Tidal Marsh Soil Organic Carbon (MarSOC) Dataset

The repository is formatted in the following structure: - README.md: markdown file with repository description - MarSOC-Dataset.Rproj: R project file - useful when using RStudio - Maxwell_MarSOC_dataset.csv: .csv file containing the final dataset. The data structure is described in the metadata file. It contains 17,454 records distributed amongst 29 countries. - Maxwell_MarSOC_dataset_metadata.csv: .csv file containing the main data file metadata (equivalent to Table 1). - data_paper/: folder containing the list of studies included in the dataset, as well as figures for this data paper (generated from the following R script: ‘reports/04_data_process/scripts/04_data-paper_data_clean.R’). - reports/01_litsearchr/: folder containing .bib files with references from the original naive search, a .Rmd document describing the litsearchr analysis using nodes to go from the naive search to the final search string, and the .bib files from this final search, which were then imported into sysrev for abstract screening. - reports/02_sysrev/: folder with .csv files exported from sysrev after abstract screening. These files contain the included studies with their various labels. - reports/03_data_format/: folder containing all original data, associated scripts, and exported data. - reports/04_data_process/: folder containing data processing scripts to bind and clean the exported data, as well as a script testing the different models for predicting soil organic carbon from organic matter and finalising the equation using all available data. A script testing and removing outliers is also included

Male breast cancer in BRCA1 and BRCA2 mutation carriers: pathology data from the Consortium of Investigators of Modifiers of BRCA1/2

Abstract Background BRCA1 and, more commonly, BRCA2 mutations are associated with increased risk of male breast cancer (MBC). However, only a paucity of data exists on the pathology of breast cancers (BCs) in men with BRCA1/2 mutations. Using the largest available dataset, we determined whether MBCs arising in BRCA1/2 mutation carriers display specific pathologic features and whether these features differ from those of BRCA1/2 female BCs (FBCs). Methods We characterised the pathologic features of 419 BRCA1/2 MBCs and, using logistic regression analysis, contrasted those with data from 9675 BRCA1/2 FBCs and with population-based data from 6351 MBCs in the Surveillance, Epidemiology, and End Results (SEER) database. Results Among BRCA2 MBCs, grade significantly decreased with increasing age at diagnosis (P = 0.005). Compared with BRCA2 FBCs, BRCA2 MBCs were of significantly higher stage (P for trend = 2 × 10−5) and higher grade (P for trend = 0.005) and were more likely to be oestrogen receptor–positive [odds ratio (OR) 10.59; 95 % confidence interval (CI) 5.15–21.80] and progesterone receptor–positive (OR 5.04; 95 % CI 3.17–8.04). With the exception of grade, similar patterns of associations emerged when we compared BRCA1 MBCs and FBCs. BRCA2 MBCs also presented with higher grade than MBCs from the SEER database (P for trend = 4 × 10−12). Conclusions On the basis of the largest series analysed to date, our results show that BRCA1/2 MBCs display distinct pathologic characteristics compared with BRCA1/2 FBCs, and we identified a specific BRCA2-associated MBC phenotype characterised by a variable suggesting greater biological aggressiveness (i.e., high histologic grade). These findings could lead to the development of gender-specific risk prediction models and guide clinical strategies appropriate for MBC management

Gaia DR2. Variable stars in CMD

VizieR online Data Catalogue associated with article published in journal Astronomy & Astrophysics with title 'Gaia Data Release 2. Variable stars in the colour-absolute magnitude diagram.' (bibcode: 2019A&A...623A.110G

Gaia DR1

VizieR Gaia DR1 Catalogue is the CDS version of data provided by the European Space Agency, 2016, Gaia DR1, Version 1.0. - https://doi.org/10.5270/esa-ogmeul

Gaia DR2

VizieR Gaia DR2 Catalogue is the CDS version of data provided by the European Space Agency, 2018, Gaia DR2, Version 1.0. https://doi.org/10.5270/esa-ycsawu7 Gaia Data Release 2. Summary of the contents and survey properties: We present the second Gaia data release, Gaia DR2, consisting of astrometry, photometry, radial velocities, and information on as- trophysical parameters and variability, for sources brighter than magnitude 21. In addition epoch astrometry and photometry are provided for a modest sample of minor planets in the solar system. A summary of the contents of Gaia DR2 is presented, accompanied by a discussion on the differences with respect to Gaia DR1 and an overview of the main limitations which are still present in the survey. Recommendations are made on the responsible use of Gaia DR2 results. Methods. The raw data collected with the Gaia instruments during the first 22 months of the mission have been processed by the Gaia Data Processing and Analysis Consortium (DPAC) and turned into this second data release, which represents a major advance with respect to Gaia DR1 in terms of completeness, performance, and richness of the data products. Gaia DR2 contains celestial positions and the apparent brightness in G for approximately 1.7 billion sources. For 1.3 billion of those sources, parallaxes and proper motions are in addition available. The sample of sources for which variability information is provided is expanded to 0.5 million stars. This data release contains four new elements: broad-band colour information in the form of the apparent brightness in the GBP (330-680nm) and GRP (630-1050nm) bands is available for 1.4 billion sources; median radial velocities for some 7 million sources are presented; for between 77 and 161 million sources estimates are provided of the stellar effective temperature, extinction, reddening, and radius and luminosity; and for a pre-selected list of 14000 minor planets in the solar system epoch astrometry and photometry are presented. Finally, Gaia DR2 also represents a new materialisation of the celestial reference frame in the optical, the Gaia-CRF2, which is the first optical reference frame based solely on extragalactic sources. There are notable changes in the photometric system and the catalogue source list with respect to Gaia DR1, and we stress the need to consider the two data releases as independent. Gaia DR2 represents a major achievement for the Gaia mission, delivering on the long standing promise to provide parallaxes and proper motions for over 1 billion stars, and representing a first step in the availability of complementary radial velocity and source astrophysical information for a sample of stars in the Gaia survey which covers a very substantial fraction of the volume of our galaxy. The catalogue of radial velocity standard stars (Soubiran et al., 2018A&A...616A...7S 2018A&A...616A...7S) The Radial Velocity Spectrometer (RVS) on board of Gaia having no calibration device, the zero point of radial velocities needs to be calibrated with stars proved to be stable at the level of 300m/s during the Gaia observations. A dataset of about 71000 ground-based radial velocity measurements from five high resolution spectrographs has been compiled. A catalogue of 4813 stars was built by combining these individual measurements. The zero point has been established using asteroids. The resulting catalogue has 7 observations per star on average on a typical time baseline of 6 years, with a median standard deviation of 15m/s. A subset of the most stable stars fulfilling the RVS requirements has been used to establish the zero point of the radial velocities provided in Gaia DR2. The stars not used for calibration are used for the RVS data validation