Evaluation of Early Maturing Sorghum and Cowpea Varieties Intercropping for Animal Nutritive Value and in vitro Dry Matter Digestibility in Fedis District, Eastern Ethiopia

The shortage of arable land and shortage of livestock feed are major constraints in East Hararghe Zone. Thus, a field study was conducted to evaluate an early maturing sorghum varieties and cowpea genotypes intercropping for both food and feed production at Fedis Agricultural Research Center, eastern Ethiopia in 2018 cropping season. Two cowpea genotypes(lines) (9333 and 9334) were intercropped with three varieties of early maturing sorghum (Teshale, Birhan and Melkam) and compared with sole cropping of all the varieties, which were laid out in a randomized complete block design with three replications. The analyzed result showed the NDF content was significantly different (p < 0.05) among intercropped and sole sorghum the maximum NDF was recorded from sole sorghum Teshale (69.56%) and the minimum sorghum Birhan + cowpea (9333)(57.75%) and the Intercropping sorghum improved the CP of sorghum stover mean from sole (5.31%) to intercropped (6.03%). the . Cropping systems and cowpea genotypes were significantly affected (p < 0.05) the content of CP and NDF. The maximum CP obtained from cowpea (9334) + sorghum Teshale 29.19%), and the minimum CP obtained from sole cowpea (9333) (24.38%).Generally, the results of this study showed that intercropping of sorghum-cowpea were increased the productivity of grain yields and biomass yields of sorghum varieties and it increased nutritional quality of cowpea and sorghum stover. Based on the results of this study, it could be concluded that intercropping sorghum with forage cowpea; preferably sorghum Melkam + cowpea (9333) to be appropriate to increase quality of sorghum stover in the study area. Keywords: Chemical composition, Digestibility and Forage legumes DOI: 10.7176/FSQM/107-01 Publication date: April 30th 202

Performance Evaluation of Improved Forage Trees (Sesbania sesban) Cultivars for Animal feed and Nutritional Quality in Highlands of East Hararghe Zone, Oromia, Ethiopia

The experiment was conducted to evaluate the biomass yield and adaptability of five accession with one local check of Sesbania (Sesbania sesban) at Highland of Eastern Hararghe Zone in 2017/18 and 2018/19 G.C cropping season consecutive years on-FTC in Burka Jalala PA. The treatments evaluated were S.sesban 15019, S.sesban 10865, S.sesban 15036, S.sesban 10885, S.sesban 1238 and local check in a Randomized Complete Block Design (RCBD) with three replications. The biomass yield, plant height, stem weight, leaf to stem ratio (LSR) were taken at Annual. The analysis result indicated in Table (1) showed that there was significant (P < 0.05) variation among the accession in fresh leaf weight, fresh stem weight and percent of leaf to stem ratio. The results indicated that the maximum fresh leaf biomass yield of the accession S.sesban 1238 (7.91 ton ha-1), flowed by accessions S.sesban 10885 (7.23 ton ha-1). The results showed that the maximum leaf to stem ratio were recorded under accession S.sesban 10865(28.67%), S.sesban 15019(27.66%) and S.sesban 1238(31.33%). A significant variation (p < 0.05) among the content of total ash and Acid detergent lignin. The maximum Acid detergent lignin obtained from S.sesban 15036(22.746%), and the minimum Acid detergent lignin obtained from S.sesban 1238(14.875%) and S.sesban 10885(14.874%). It was concluded that the accessions S.sesban 1238 and S.sesban 10885 were found promising to be demonstrated under in the study areas and same agro-climatic conditions similar to study area. Keywords: Forage Trees, Quality forage, Sesbania Sesban, Tree legumes DOI: 10.7176/FSQM/106-02 Publication date:March 31st 202

Antiparasitic Activity of Tea Tree Oil (TTO) and Its Components against Medically Important Ectoparasites: A Systematic Review

Ectoparasites are pathogens that can infect the skin and cause immense pain, discomfort, and disease. They are typically managed with insecticides. However, the fast-emerging antimicrobial resistance and the slow rate of development of new bio-actives combined with environmental and health concerns over the continued use of neurotoxic insecticides warrant newer and alternative methods of control. Tea tree oil (TTO), as an alternative agent, has shown remarkable promise against ectoparasites in recent studies. To our knowledge, this is the first systematic review to assess preclinical and clinical studies exploring the antiparasitic activity of TTO and its components against clinically significant ectoparasites, such as Demodex mites, scabies mites, house dust mites, lice, fleas, chiggers, and bed bugs. We systematically searched databases, including PubMed, MEDLINE (EBSCOhost), Embase (Scopus), CENTRAL, Cochrane Library, CINAHL, ScienceDirect, Web of Science, SciELO, and LILACS in any language from inception to 4 April 2022. Studies exploring the therapeutic activity of TTO and its components against the ectoparasites were eligible. We used the ToxRTool (Toxicological data reliability assessment) tool, the Joanna Briggs Institute (JBI) critical appraisal tools, and the Jadad scale to assess the methodological qualities of preclinical (in vitro and in vivo) studies, non-randomised controlled trials (including cohort, case series, and case studies), and randomised controlled trials, respectively. Of 497 identified records, 71 studies were included in this systematic review, and most (66%) had high methodological quality. The findings of this review revealed the promising efficacy of TTO and its components against ectoparasites of medical importance. Most importantly, the compelling in vitro activity of TTO against ectoparasites noted in this review seems to have translated well into the clinical environment. The promising outcomes observed in clinical studies provide enough evidence to justify the use of TTO in the pharmacotherapy of ectoparasitic infections

Density and Seasoning Characteristics of Pinus caribaea Lumber Grown at Suba Forest, Oromia, Ethiopia

Determination of the seasoning characteristics, physical and mechanical properties of lumber species is helpful in identifying the main factors affecting the quality, suitability and overall performance of wood and wood-based products. The Pinus caribaea has been considered as industrial lumber species and there is a little study conducted in identifying the physical characteristics which on turn affects the quality of product derived from the lumber. Therefore, this study aimed at evaluating the density and seasoning characteristics of P. caribaea lumber. Sample trees were harvested from Suba Forest Oromia, Ethiopia. The experiments were carried out using air and kiln seasoning methods. To measure the initial moisture content, seasoning rate, shrinkage, wood density, and seasoning defects, six replicates of samples from each tree portions were prepared when green and promptly weighed. Analysis of variance (ANOVA) has been employed in interpreting the experimental results. The obtained results have shown that the mean initial moisture content for air stacks was 78.2% while for the kiln seasoning stacks 82.9%. Seasoning time for sawn boards of 3 cm thick to reach 17% moisture continent (MC) required 61 days, while for kiln seasoning took 4.3 days to reach 14.62% MC. This showed that kiln seasoning was about 14 times faster than air seasoning. In air seasoning the MC (%) of the lumber from 78.2% to 16.9%; and, the obtained mean values of shrinkages were tangential (3.6%), radial (1.9%) and volumetric (5.4%). The initial moisture content (IMC) and green density (GD) of the lumber were significant difference along the tree height at a 95% probability level. The seasoning rate % and final MC (%) along the tree height were significant difference at 95% probability level, while the seasoning rate % and final MC were significant difference between seasoning methods at 99% probability level. Seasoning defects such as cup, bow, twist, and crook were observed on kiln seasoned. In addition, end checks and splits were observed on air seasoned boards. Therefore, the experimental factors should be monitored and optimized properly to obtain the lumber with good quality and utilize it for different purposes, including construction and industrial applications

How Do We Combat Bogus Medicines in the Age of the COVID-19 Pandemic?

The COVID-19 pandemic has brought concurrent challenges. The increased incidence of fake and falsified product distribution is one of these problems with tremendous impact, especially in low- and middle-income countries. Up to a tenth of medicines including antibiotics and antimalarial drugs in the African market are considered falsified. Pandemics make this worse by creating an ecosystem of confusion, distraction, and vulnerability stemming from the pandemic as health systems become more stressed and the workload of individuals increased. These environments create opportunities for substandard and falsified medicines to be more easily introduced into the marketplace by unscrupulous operators. In this work, we discussed some of the challenges with fake or falsified product distribution in the context of COVID-19 and proposed strategies to best manage this problem

Psychosocial factors in patients with kidney failure and role for social worker : a secondary data audit

Background: People with kidney failure face a multitude of psychosocial stressors that affect disease trajectory and health outcomes. Objectives: To investigate psychosocial factors affecting people with kidney failure before or at start of kidney replacement therapy (KRT) and kidney supportive and palliative care (KSPC) phases of illness and to explore role of social worker during the illness trajectory. Methods: We conducted a secondary data audit of patients either before or at start of KRT (Phase 1) and at the KSPC (Phase 2) of illness and had psychosocial assessments between March 2012 and March 2020 in an Australian setting. Results: Seventy-nine individuals, aged 70 ± 12 years, had at least two psychosocial assessments, one in each of the two phases of illness. The median time between social worker evaluations in Phase 1 and Phase 2 was 522 (116−943) days. Adjustment to illness and treatment (90%) was the most prevalent psychosocial issue identified in Phase 1, which declined to 39% in Phase 2. Need for aged care assistance (7.6%−63%; p < 0.001) and carer support (7.6%−42%; p < 0.001) increased significantly from Phase 1 to Phase 2. There was a significant increase in psychosocial interventions by the social worker in Phase 2, including supportive counselling (53%−73%; p < 0.05), provision of education and information (43%−65%; p < 0.01), and referrals (28%−62%; p < 0.01). Conclusion: Adults nearing or at the start of KRT experience immense psychosocial burden and adaptive demands that recognisably change during the course of illness. The positive role played by the nephrology social worker warrants further investigation

Healthcare Access and Quality Index based on mortality from causes amenable to personal health care in 195 countries and territories, 1990-2015 : a novel analysis from the Global Burden of Disease Study 2015

Background National levels of personal health-care access and quality can be approximated by measuring mortality rates from causes that should not be fatal in the presence of effective medical care (ie, amenable mortality). Previous analyses of mortality amenable to health care only focused on high-income countries and faced several methodological challenges. In the present analysis, we use the highly standardised cause of death and risk factor estimates generated through the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) to improve and expand the quantification of personal health-care access and quality for 195 countries and territories from 1990 to 2015. Methods We mapped the most widely used list of causes amenable to personal health care developed by Nolte and McKee to 32 GBD causes. We accounted for variations in cause of death certification and misclassifications through the extensive data standardisation processes and redistribution algorithms developed for GBD. To isolate the effects of personal health-care access and quality, we risk-standardised cause-specific mortality rates for each geography-year by removing the joint effects of local environmental and behavioural risks, and adding back the global levels of risk exposure as estimated for GBD 2015. We employed principal component analysis to create a single, interpretable summary measure-the Healthcare Quality and Access (HAQ) Index-on a scale of 0 to 100. The HAQ Index showed strong convergence validity as compared with other health-system indicators, including health expenditure per capita (r= 0.88), an index of 11 universal health coverage interventions (r= 0.83), and human resources for health per 1000 (r= 0.77). We used free disposal hull analysis with bootstrapping to produce a frontier based on the relationship between the HAQ Index and the Socio-demographic Index (SDI), a measure of overall development consisting of income per capita, average years of education, and total fertility rates. This frontier allowed us to better quantify the maximum levels of personal health-care access and quality achieved across the development spectrum, and pinpoint geographies where gaps between observed and potential levels have narrowed or widened over time. Findings Between 1990 and 2015, nearly all countries and territories saw their HAQ Index values improve; nonetheless, the difference between the highest and lowest observed HAQ Index was larger in 2015 than in 1990, ranging from 28.6 to 94.6. Of 195 geographies, 167 had statistically significant increases in HAQ Index levels since 1990, with South Korea, Turkey, Peru, China, and the Maldives recording among the largest gains by 2015. Performance on the HAQ Index and individual causes showed distinct patterns by region and level of development, yet substantial heterogeneities emerged for several causes, including cancers in highest-SDI countries; chronic kidney disease, diabetes, diarrhoeal diseases, and lower respiratory infections among middle-SDI countries; and measles and tetanus among lowest-SDI countries. While the global HAQ Index average rose from 40.7 (95% uncertainty interval, 39.0-42.8) in 1990 to 53.7 (52.2-55.4) in 2015, far less progress occurred in narrowing the gap between observed HAQ Index values and maximum levels achieved; at the global level, the difference between the observed and frontier HAQ Index only decreased from 21.2 in 1990 to 20.1 in 2015. If every country and territory had achieved the highest observed HAQ Index by their corresponding level of SDI, the global average would have been 73.8 in 2015. Several countries, particularly in eastern and western sub-Saharan Africa, reached HAQ Index values similar to or beyond their development levels, whereas others, namely in southern sub-Saharan Africa, the Middle East, and south Asia, lagged behind what geographies of similar development attained between 1990 and 2015. Interpretation This novel extension of the GBD Study shows the untapped potential for personal health-care access and quality improvement across the development spectrum. Amid substantive advances in personal health care at the national level, heterogeneous patterns for individual causes in given countries or territories suggest that few places have consistently achieved optimal health-care access and quality across health-system functions and therapeutic areas. This is especially evident in middle-SDI countries, many of which have recently undergone or are currently experiencing epidemiological transitions. The HAQ Index, if paired with other measures of health-systemcharacteristics such as intervention coverage, could provide a robust avenue for tracking progress on universal health coverage and identifying local priorities for strengthening personal health-care quality and access throughout the world. Copyright (C) The Author(s). Published by Elsevier Ltd.Peer reviewe

Self-reported medication adherence measurement tools: Some options to avoid a legal minefield

What is known and objective: Self-report questionnaires are used to measure medication adherence, often times both clinically and for research purposes. Despite thepresence of several published tools, some may have prohibitive licensure and fee requirements, which researchers should be aware of prior to using them. This paperpresents a summary of selected self-report measures, which have been developedand validated in various health conditions and can be used free of cost.Comment: Our review identified self-report tools that are valid to measure medication adherence in different chronic health conditions. Most of these tools measureboth intentional and unintentional non-adherence and have shown good correlationwith relevant clinical outcomes.What is new and conclusion: Given the potential copyright risks associated with usingsome of the self-report measures of adherence, an improved awareness and understanding of the available self-report questionnaires will better facilitate the decisionby researchers to select appropriate tools relevant to their studies