10 research outputs found
UK National Ecosystem Assessment Follow-on Work Package Report 10: Tools – Applications, Benefi ts and Linkages for Ecosystem Science (TABLES)
Computational design of faster rotating second-generation light-driven molecular motors by control of steric effects
Battling on the Home Front: Posttraumatic Stress Disorder and Conflict Behavior Among Military Couples
Relationship Distress in Partners of Combat Veterans: The Role of Partners’ Perceptions of Posttraumatic Stress Symptoms
Comparing the predictive capacity of observed in-session resistance to self-reported motivation in cognitive behavioral therapy
Adding a motivational interviewing pretreatment to cognitive behavioral therapy for generalized anxiety disorder: A preliminary randomized controlled trial
Temperature Dependence of Interactions between Stable Piperidine-1-yloxyl Derivatives and an Ionic Liquid
The indispensable roles of microglia and astrocytes during brain development
Glia are essential for brain functioning during development and in the adult brain. Here, we discuss the various roles of both microglia and astrocytes, and their interactions during brain development. Although both cells are fundamentally different in origin and function, they often affect the same developmental processes such as neuro-/gliogenesis, angiogenesis, axonal outgrowth, synaptogenesis and synaptic pruning. Due to their important instructive roles in these processes, dysfunction of microglia or astrocytes during brain development could contribute to neurodevelopmental disorders and potentially even late-onset neuropathology. A better understanding of the origin, differentiation process and developmental functions of microglia and astrocytes will help to fully appreciate their role both in the developing as well as in the adult brain, in health and disease