515 research outputs found
First narrow-band search for continuous gravitational waves from known pulsars in advanced detector data
Spinning neutron stars asymmetric with respect to their rotation axis are potential sources of
continuous gravitational waves for ground-based interferometric detectors. In the case of known pulsars a
fully coherent search, based on matched filtering, which uses the position and rotational parameters
obtained from electromagnetic observations, can be carried out. Matched filtering maximizes the signalto-
noise (SNR) ratio, but a large sensitivity loss is expected in case of even a very small mismatch
between the assumed and the true signal parameters. For this reason, narrow-band analysis methods have
been developed, allowing a fully coherent search for gravitational waves from known pulsars over a
fraction of a hertz and several spin-down values. In this paper we describe a narrow-band search of
11 pulsars using data from Advanced LIGO’s first observing run. Although we have found several initial
outliers, further studies show no significant evidence for the presence of a gravitational wave signal.
Finally, we have placed upper limits on the signal strain amplitude lower than the spin-down limit for 5 of
the 11 targets over the bands searched; in the case of J1813-1749 the spin-down limit has been beaten for
the first time. For an additional 3 targets, the median upper limit across the search bands is below the
spin-down limit. This is the most sensitive narrow-band search for continuous gravitational waves carried
out so far
The Mice at play in the CALIFA survey: A case study of a gas-rich major merger between first passage and coalescence
We present optical integral field spectroscopy (IFS) observations of the
Mice, a major merger between two massive (>10^11Msol) gas-rich spirals NGC4676A
and B, observed between first passage and final coalescence. The spectra
provide stellar and gas kinematics, ionised gas properties and stellar
population diagnostics, over the full optical extent of both galaxies. The Mice
provide a perfect case study highlighting the importance of IFS data for
improving our understanding of local galaxies. The impact of first passage on
the kinematics of the stars and gas has been significant, with strong bars
likely induced in both galaxies. The barred spiral NGC4676B exhibits a strong
twist in both its stellar and ionised gas disk. On the other hand, the impact
of the merger on the stellar populations has been minimal thus far: star
formation induced by the recent close passage has not contributed significantly
to the global star formation rate or stellar mass of the galaxies. Both
galaxies show bicones of high ionisation gas extending along their minor axes.
In NGC4676A the high gas velocity dispersion and Seyfert-like line ratios at
large scaleheight indicate a powerful outflow. Fast shocks extend to ~6.6kpc
above the disk plane. The measured ram pressure and mass outflow rate
(~8-20Msol/yr) are similar to superwinds from local ULIRGs, although NGC4676A
has only a moderate infrared luminosity of 3x10^10Lsol. Energy beyond that
provided by the mechanical energy of the starburst appears to be required to
drive the outflow. We compare the observations to mock kinematic and stellar
population maps from a merger simulation. The models show little enhancement in
star formation during and following first passage, in agreement with the
observations. We highlight areas where IFS data could help further constrain
the models.Comment: 23 pages, 13 figures, accepted to A&A. A version with a complete set
of high resolution figures is available here:
http://www-star.st-and.ac.uk/~vw8/resources/mice_v8_astroph.pd
Association of nutritional status and serum albumin levels with development of toxicity in patients with advanced non-small cell lung cancer treated with paclitaxel-cisplatin chemotherapy: a prospective study
<p>Abstract</p> <p>Background</p> <p>A frequent manifestation of advanced NSCLC is malnutrition, even though there are many studies which relate it with a poor survival, its relation with toxicity has not yet been consistently reported. The aim of this study was to associate malnutrition and albumin serum levels with the occurrence of chemotherapy-induced toxicity in cisplatin plus paclitaxel chemotherapy-treated NSCLC.</p> <p>Methods</p> <p>We prospectively evaluated 100 stage IV NSCLC patients treated with paclitaxel (175 mg/m<sup>2</sup>) and cisplatin (80 mg/m<sup>2</sup>). Malnutrition was assessed using SGA prior treatment. Neutrophil Lymphocyte Ratio (NLR) and the Platelet Lymphocyte Ratio (PLR) were used to determine the presence of systemic inflammatory response (SIR) and were related to the development of toxicity. Toxicity was graded according to NCI CTCAE version 3.0 after two chemotherapy cycles.</p> <p>Results</p> <p>Median age was 58 ± 10 years, 51% of patients were malnourished, 50% had albumin ≤3.0 mg/mL. NLR ≥ 5 was associated with basal hypoalbuminemia (mean ranks, 55.7 vs. 39 p = 0.006), ECOG = 2 (47.2 vs. 55.4 p = 0.026) and PLR ≥ 150 were significantly related with a basal body mass index ≤20 (56.6 vs. 43.5; p = 0.02) and hypoalbuminemia (58.9 vs. 41.3; p = 0.02). Main toxicities observed after 2 cycles of chemotherapy were alopecia (84%), nausea (49%), neuropathy (46%), anemia (33%), lymphopenia (31%), and leukopenia (30%). Patients malnourished and with hypoalbuminemia developed more chemotherapy-induced toxicity overall when compared with those without malnutrition (31 vs 22; <it>p </it>= 0.02) and normal albumin (mean ranks, 62 vs 43; <it>p </it>= 0.002), respectively. Hypoalbuminemia was associated with anemia (56 vs 47; <it>p </it>= 0.05), fatigue (58 vs 46; <it>p </it>= 0.01), and appetite loss (57.1 vs 46.7; <it>p </it>= 0.004) compared with normal albumin. PLR ≥ 150 was related with the development of toxicity grade III/IV (59.27 vs. 47.03 p = 0.008) and anemia (37.9 vs 53.8 p = 0.004).</p> <p>Conclusion</p> <p>SIR parameters were associated with malnutrition, weight loss and hypoalbuminemia. Chemotherapy-induced toxicity in NSCLC patients treated with paclitaxel and cisplatin was associated with malnutrition and hypoalbuminemia. Early nutritional assessment and support might confer beneficial effects.</p
Virgo Detector Characterization and Data Quality during the O3 run
The Advanced Virgo detector has contributed with its data to the rapid growth
of the number of detected gravitational-wave signals in the past few years,
alongside the two LIGO instruments. First, during the last month of the
Observation Run 2 (O2) in August 2017 (with, most notably, the compact binary
mergers GW170814 and GW170817) and then during the full Observation Run 3 (O3):
an 11 months data taking period, between April 2019 and March 2020, that led to
the addition of about 80 events to the catalog of transient gravitational-wave
sources maintained by LIGO, Virgo and KAGRA. These discoveries and the manifold
exploitation of the detected waveforms require an accurate characterization of
the quality of the data, such as continuous study and monitoring of the
detector noise. These activities, collectively named {\em detector
characterization} or {\em DetChar}, span the whole workflow of the Virgo data,
from the instrument front-end to the final analysis. They are described in
details in the following article, with a focus on the associated tools, the
results achieved by the Virgo DetChar group during the O3 run and the main
prospects for future data-taking periods with an improved detector.Comment: 86 pages, 33 figures. This paper has been divided into two articles
which supercede it and have been posted to arXiv on October 2022. Please use
these new preprints as references: arXiv:2210.15634 (tools and methods) and
arXiv:2210.15633 (results from the O3 run
Virgo Detector Characterization and Data Quality: results from the O3 run
The Advanced Virgo detector has contributed with its data to the rapid growth
of the number of detected gravitational-wave (GW) signals in the past few
years, alongside the two Advanced LIGO instruments. First during the last month
of the Observation Run 2 (O2) in August 2017 (with, most notably, the compact
binary mergers GW170814 and GW170817), and then during the full Observation Run
3 (O3): an 11-months data taking period, between April 2019 and March 2020,
that led to the addition of about 80 events to the catalog of transient GW
sources maintained by LIGO, Virgo and now KAGRA. These discoveries and the
manifold exploitation of the detected waveforms require an accurate
characterization of the quality of the data, such as continuous study and
monitoring of the detector noise sources. These activities, collectively named
{\em detector characterization and data quality} or {\em DetChar}, span the
whole workflow of the Virgo data, from the instrument front-end hardware to the
final analyses. They are described in details in the following article, with a
focus on the results achieved by the Virgo DetChar group during the O3 run.
Concurrently, a companion article describes the tools that have been used by
the Virgo DetChar group to perform this work.Comment: 57 pages, 18 figures. To be submitted to Class. and Quantum Grav.
This is the "Results" part of preprint arXiv:2205.01555 [gr-qc] which has
been split into two companion articles: one about the tools and methods, the
other about the analyses of the O3 Virgo dat
Virgo Detector Characterization and Data Quality: tools
Detector characterization and data quality studies -- collectively referred
to as {\em DetChar} activities in this article -- are paramount to the
scientific exploitation of the joint dataset collected by the LIGO-Virgo-KAGRA
global network of ground-based gravitational-wave (GW) detectors. They take
place during each phase of the operation of the instruments (upgrade, tuning
and optimization, data taking), are required at all steps of the dataflow (from
data acquisition to the final list of GW events) and operate at various
latencies (from near real-time to vet the public alerts to offline analyses).
This work requires a wide set of tools which have been developed over the years
to fulfill the requirements of the various DetChar studies: data access and
bookkeeping; global monitoring of the instruments and of the different steps of
the data processing; studies of the global properties of the noise at the
detector outputs; identification and follow-up of noise peculiar features
(whether they be transient or continuously present in the data); quick
processing of the public alerts. The present article reviews all the tools used
by the Virgo DetChar group during the third LIGO-Virgo Observation Run (O3,
from April 2019 to March 2020), mainly to analyse the Virgo data acquired at
EGO. Concurrently, a companion article focuses on the results achieved by the
DetChar group during the O3 run using these tools.Comment: 44 pages, 16 figures. To be submitted to Class. and Quantum Grav.
This is the "Tools" part of preprint arXiv:2205.01555 [gr-qc] which has been
split into two companion articles: one about the tools and methods, the other
about the analyses of the O3 Virgo dat
First measurement of the Hubble Constant from a Dark Standard Siren using the Dark Energy Survey Galaxies and the LIGO/Virgo Binary–Black-hole Merger GW170814
International audienceWe present a multi-messenger measurement of the Hubble constant H 0 using the binary–black-hole merger GW170814 as a standard siren, combined with a photometric redshift catalog from the Dark Energy Survey (DES). The luminosity distance is obtained from the gravitational wave signal detected by the Laser Interferometer Gravitational-Wave Observatory (LIGO)/Virgo Collaboration (LVC) on 2017 August 14, and the redshift information is provided by the DES Year 3 data. Black hole mergers such as GW170814 are expected to lack bright electromagnetic emission to uniquely identify their host galaxies and build an object-by-object Hubble diagram. However, they are suitable for a statistical measurement, provided that a galaxy catalog of adequate depth and redshift completion is available. Here we present the first Hubble parameter measurement using a black hole merger. Our analysis results in , which is consistent with both SN Ia and cosmic microwave background measurements of the Hubble constant. The quoted 68% credible region comprises 60% of the uniform prior range [20, 140] km s−1 Mpc−1, and it depends on the assumed prior range. If we take a broader prior of [10, 220] km s−1 Mpc−1, we find (57% of the prior range). Although a weak constraint on the Hubble constant from a single event is expected using the dark siren method, a multifold increase in the LVC event rate is anticipated in the coming years and combinations of many sirens will lead to improved constraints on H 0
A search of the Orion spur for continuous gravitational waves using a "loosely coherent" algorithm on data from LIGO interferometers
We report results of a wideband search for periodic gravitational waves from
isolated neutron stars within the Orion spur towards both the inner and outer
regions of our Galaxy. As gravitational waves interact very weakly with matter,
the search is unimpeded by dust and concentrations of stars. One search disk
(A) is in diameter and centered on
, and the other
(B) is in diameter and centered on
. We explored the
frequency range of 50-1500 Hz and frequency derivative from to Hz/s. A multi-stage, loosely coherent search program allowed probing
more deeply than before in these two regions, while increasing coherence length
with every stage.
Rigorous followup parameters have winnowed initial coincidence set to only 70
candidates, to be examined manually. None of those 70 candidates proved to be
consistent with an isolated gravitational wave emitter, and 95% confidence
level upper limits were placed on continuous-wave strain amplitudes. Near
Hz we achieve our lowest 95% CL upper limit on worst-case linearly polarized
strain amplitude of , while at the high end of our
frequency range we achieve a worst-case upper limit of for
all polarizations and sky locations.Comment: Fixed minor typo - duplicate name in the author lis
Search of the Orion spur for continuous gravitational waves using a loosely coherent algorithm on data from LIGO interferometers
We report results of a wideband search for periodic gravitational waves from isolated neutron stars within the Orion spur towards both the inner and outer regions of our Galaxy. As gravitational waves interact very weakly with matter, the search is unimpeded by dust and concentrations of stars. One search disk (A) is 6.87° in diameter and centered on 20h10m54.71s+33°33′25.29′′, and the other (B) is 7.45° in diameter and centered on 8h35m20.61s-46°49′25.151′′. We explored the frequency range of 50-1500 Hz and frequency derivative from 0 to -5×10-9 Hz/s. A multistage, loosely coherent search program allowed probing more deeply than before in these two regions, while increasing coherence length with every stage. Rigorous follow-up parameters have winnowed the initial coincidence set to only 70 candidates, to be examined manually. None of those 70 candidates proved to be consistent with an isolated gravitational-wave emitter, and 95% confidence level upper limits were placed on continuous-wave strain amplitudes. Near 169 Hz we achieve our lowest 95% C.L. upper limit on the worst-case linearly polarized strain amplitude h0 of 6.3×10-25, while at the high end of our frequency range we achieve a worst-case upper limit of 3.4×10-24 for all polarizations and sky locations. © 2016 American Physical Society
- …