101 research outputs found
Hadronic Parity Violation and Inelastic Electron-Deuteron Scattering
We compute contributions to the parity-violating (PV) inelastic
electron-deuteron scattering asymmetry arising from hadronic PV. While hadronic
PV effects can be relatively important in PV threshold electro- disintegration,
we find that they are highly suppressed at quasielastic kinematics. The
interpretation of the PV quasielastic asymmetry is, thus, largely unaffected by
hadronic PV.Comment: 27 pages, 13 figures, uses REVTeX and BibTe
Effective Field Theory Dimensional Regularization
A Lorentz-covariant regularization scheme for effective field theories with
an arbitrary number of propagating heavy and light particles is given. This
regularization scheme leaves the low-energy analytic structure of Greens
functions intact and preserves all the symmetries of the underlying Lagrangian.
The power divergences of regularized loop integrals are controlled by the
low-energy kinematic variables. Simple diagrammatic rules are derived for the
regularization of arbitrary one-loop graphs and the generalization to higher
loops is discussed.Comment: 22 pages, 11 figures and 1 tabl
Development of subtype-selective photoswitchable positive allosteric modulators for mGlu receptors
Positive allosteric modulators (PAMs) for metabotropic glutamate receptors have been
postulated to treat neuropsychiatric diseases. Besides, obtaining a reversible and efficient
spatiotemporal control of mGlu activity would be therapeutically advantageous.
Photopharmacology may provide a solution on this topic, since it is based on the use of light and
photoswitchable ligands to modulate a protein activity. This approach offers new perspectives
for drug discovery and promises a better drug action control reducing side effects to unattained
levels.Peer reviewe
Planck 2013 results. XXII. Constraints on inflation
We analyse the implications of the Planck data for cosmic inflation. The Planck nominal mission temperature anisotropy measurements, combined with the WMAP large-angle polarization, constrain the scalar spectral index to be ns = 0:9603 _ 0:0073, ruling out exact scale invariance at over 5_: Planck establishes an upper bound on the tensor-to-scalar ratio of r < 0:11 (95% CL). The Planck data thus shrink the space of allowed standard inflationary models, preferring potentials with V00 < 0. Exponential potential models, the simplest hybrid inflationary models, and monomial potential models of degree n _ 2 do not provide a good fit to the data. Planck does not find statistically significant running of the scalar spectral index, obtaining dns=dln k = 0:0134 _ 0:0090. We verify these conclusions through a numerical analysis, which makes no slowroll approximation, and carry out a Bayesian parameter estimation and model-selection analysis for a number of inflationary models including monomial, natural, and hilltop potentials. For each model, we present the Planck constraints on the parameters of the potential and explore several possibilities for the post-inflationary entropy generation epoch, thus obtaining nontrivial data-driven constraints. We also present a direct reconstruction of the observable range of the inflaton potential. Unless a quartic term is allowed in the potential, we find results consistent with second-order slow-roll predictions. We also investigate whether the primordial power spectrum contains any features. We find that models with a parameterized oscillatory feature improve the fit by __2 e_ _ 10; however, Bayesian evidence does not prefer these models. We constrain several single-field inflation models with generalized Lagrangians by combining power spectrum data with Planck bounds on fNL. Planck constrains with unprecedented accuracy the amplitude and possible correlation (with the adiabatic mode) of non-decaying isocurvature fluctuations. The fractional primordial contributions of cold dark matter (CDM) isocurvature modes of the types expected in the curvaton and axion scenarios have upper bounds of 0.25% and 3.9% (95% CL), respectively. In models with arbitrarily correlated CDM or neutrino isocurvature modes, an anticorrelated isocurvature component can improve the _2 e_ by approximately 4 as a result of slightly lowering the theoretical prediction for the ` <_ 40 multipoles relative to the higher multipoles. Nonetheless, the data are consistent with adiabatic initial conditions
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