8 research outputs found

    Taxicab Geometry

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    Taxicab geometry was founded by a gentleman named Hermann Minkowski. Mr. Minkowski was one of the developers in “non-Euclidean” geometry, which led into Einstein’s theory of relativity. Minkowski and Einstein worked together a lot on this idea Mr. Minkowski wanted people to know that the side angle side axiom does not always hold true for all geometries. He wanted to prove this in the case that you can not always use the hypotenuse to find the shortest way from one spot to another. The best way to think of his idea is to think of a taxicab going from one place to another, thus the name taxicab geometry

    How to Better Prepare for Assessment and Create a More Technologically Advanced Classroom

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    In this action research study of my classroom of 8th grade mathematics, I investigated how to better prepare these students for quizzes and how technology can be used in the classroom. I discovered that there are many different ways to challenge students and help them prepare for assessments. There are also many ways to use technology in the classroom if one has the opportunities to use some of the tools, such as Power Point and Algebra Tiles. As a result of this research, I plan to increase the scores on state standards while also allowing the students to enjoy technology during this process

    Single- and Multi-channel Whistle Recognition with NAO Robots

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    We propose two real-time sound recognition approaches that are able to distinguish a predefined whistle sound on a NAO robot in various noisy environments. The approaches use one, two, and four microphone channels of a NAO robot. The first approach is based on a frequency/band-pass filter whereas the second approach is based on logistic regression. We conducted experiments in six different settings varying the noise level of both the surrounding environment and the robot itself. The results show that the robot will be able to identify the whistle reliability even in very noisy environments

    CpG preconditioning reduces accumulation of lysophosphatidylcholine in ischemic brain tissue after middle cerebral artery occlusion

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    Ischemic stroke is one of the major causes of death and permanent disability in the world. However, the molecular mechanisms surrounding tissue damage are complex and further studies are needed to gain insights necessary for development of treatment. Prophylactic treatment by administration of cytosine-guanine (CpG) oligodeoxynucleotides has been shown to provide neuroprotection against anticipated ischemic injury. CpG binds to Toll-like receptor 9 (TLR9) causing initialization of an inflammatory response that limits visible ischemic damages upon subsequent stroke. Here, we use nanospray desorption electrospray ionization (nano-DESI) mass spectrometry imaging (MSI) to characterize molecular effects of CpG preconditioning prior to middle cerebral artery occlusion (MCAO) and reperfusion. By doping the nano-DESI solvent with appropriate internal standards, we can study and compare distributions of phosphatidylcholine (PC) and lysophosphatidylcholine (LPC) in the ischemic hemisphere of the brain despite the large changes in alkali metal abundances. Our results show that CpG preconditioning not only reduces the infarct size but it also decreases the degradation of PC and accumulation of LPC species, which indicates reduced cell membrane breakdown and overall ischemic damage. Our findings show that molecular mechanisms of PC degradation are intact despite CpG preconditioning but that these are limited due to the initialized inflammatory response

    Current and Potential Drugs for Treatment of Obesity

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